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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for AIRE

Z-value: 0.72

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Transcription factors associated with AIRE

Gene Symbol Gene ID Gene Info
AIRE
ENSG00000160224.17 AIRE

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
AIREhg38_v1_chr21_+_44285869_442858840.271.4e-01Click!

Activity profile of AIRE motif

Sorted Z-values of AIRE motif

Network of associatons between targets according to the STRING database.

First level regulatory network of AIRE

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr12_+_75480800 1.48 ENST00000456650.7
GLIPR1
GLI pathogenesis related 1
chr9_+_87497222 1.45 ENST00000358077.9
DAPK1
death associated protein kinase 1
chr20_+_59628609 1.23 ENST00000541461.5
PHACTR3
phosphatase and actin regulator 3
chr12_+_75481204 1.17 ENST00000550491.1
GLIPR1
GLI pathogenesis related 1
chr12_+_75480745 1.11 ENST00000266659.8
GLIPR1
GLI pathogenesis related 1
chr17_+_7306975 1.08 ENST00000336452.11
EIF5A
eukaryotic translation initiation factor 5A
chr18_+_63775369 0.89 ENST00000540675.5
SERPINB7
serpin family B member 7
chr10_-_100081854 0.87 ENST00000370418.8
CPN1
carboxypeptidase N subunit 1
chr19_+_55857437 0.81 ENST00000587891.5
NLRP4
NLR family pyrin domain containing 4
chr18_+_63775395 0.75 ENST00000398019.7
SERPINB7
serpin family B member 7
chr9_-_65285209 0.74 ENST00000377420.1
FOXD4L5
forkhead box D4 like 5
chr11_-_66907891 0.68 ENST00000393955.6
PC
pyruvate carboxylase
chr11_+_35189964 0.65 ENST00000524922.1
CD44
CD44 molecule (Indian blood group)
chr19_-_23687163 0.59 ENST00000601010.5
ENST00000601935.5
ENST00000600313.5
ENST00000596211.5
ENST00000359788.9
ENST00000599168.1
ZNF675
zinc finger protein 675
chr2_-_189179754 0.57 ENST00000374866.9
ENST00000618828.1
COL5A2
collagen type V alpha 2 chain
chr16_-_20697680 0.54 ENST00000520010.6
ACSM1
acyl-CoA synthetase medium chain family member 1
chr8_+_53851786 0.54 ENST00000297313.8
ENST00000344277.10
RGS20
regulator of G protein signaling 20
chr3_-_48089203 0.52 ENST00000468075.2
ENST00000360240.10
MAP4
microtubule associated protein 4
chr4_-_119322128 0.52 ENST00000274024.4
FABP2
fatty acid binding protein 2
chr6_-_39322968 0.52 ENST00000507712.5
KCNK16
potassium two pore domain channel subfamily K member 16
chr12_-_24949026 0.52 ENST00000539780.5
ENST00000546285.1
ENST00000342945.9
ENST00000261192.12
BCAT1
branched chain amino acid transaminase 1
chr2_-_237414127 0.51 ENST00000472056.5
COL6A3
collagen type VI alpha 3 chain
chrM_+_12329 0.49 ENST00000361567.2
MT-ND5
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5
chr8_+_127736046 0.46 ENST00000641036.1
ENST00000377970.6
MYC
MYC proto-oncogene, bHLH transcription factor
chr10_-_96359273 0.45 ENST00000393871.5
ENST00000419479.5
ENST00000393870.3
OPALIN
oligodendrocytic myelin paranodal and inner loop protein
chr4_+_94489030 0.45 ENST00000510099.5
PDLIM5
PDZ and LIM domain 5
chr4_-_87529460 0.45 ENST00000418378.5
SPARCL1
SPARC like 1
chr16_+_11345429 0.45 ENST00000576027.1
ENST00000312499.6
ENST00000648619.1
RMI2
RecQ mediated genome instability 2
chr2_-_208129824 0.44 ENST00000282141.4
CRYGC
crystallin gamma C
chr3_-_121749704 0.44 ENST00000393667.7
ENST00000340645.9
ENST00000614479.4
GOLGB1
golgin B1
chr5_-_78549151 0.44 ENST00000515007.6
LHFPL2
LHFPL tetraspan subfamily member 2
chr7_-_66995576 0.43 ENST00000246868.7
ENST00000617799.1
SBDS
SBDS ribosome maturation factor
chr20_+_56248732 0.43 ENST00000243911.2
MC3R
melanocortin 3 receptor
chr9_-_21482313 0.41 ENST00000448696.4
IFNE
interferon epsilon
chr14_-_81436447 0.40 ENST00000649389.1
ENST00000557055.5
STON2
stonin 2
chr2_-_224947030 0.40 ENST00000409592.7
DOCK10
dedicator of cytokinesis 10
chrX_+_154144242 0.39 ENST00000369951.9
OPN1LW
opsin 1, long wave sensitive
chr7_-_36724457 0.39 ENST00000617537.5
ENST00000435386.1
AOAH
acyloxyacyl hydrolase
chr11_-_71821548 0.38 ENST00000525199.1
ZNF705E
zinc finger protein 705E
chr6_-_137044269 0.38 ENST00000635289.1
ENST00000541547.5
IL20RA
interleukin 20 receptor subunit alpha
chr14_-_106511856 0.38 ENST00000390622.2
IGHV1-46
immunoglobulin heavy variable 1-46
chr7_-_36724543 0.38 ENST00000612871.4
AOAH
acyloxyacyl hydrolase
chr21_+_29130630 0.37 ENST00000399926.5
ENST00000399928.6
MAP3K7CL
MAP3K7 C-terminal like
chr5_+_122845488 0.37 ENST00000513881.5
SNX24
sorting nexin 24
chr15_-_99249523 0.37 ENST00000560235.1
ENST00000394132.7
ENST00000560860.5
ENST00000558078.5
ENST00000560772.5
TTC23
tetratricopeptide repeat domain 23
chr7_-_36724380 0.36 ENST00000617267.4
AOAH
acyloxyacyl hydrolase
chr8_-_7452365 0.34 ENST00000458665.5
ENST00000528168.3
SPAG11B
sperm associated antigen 11B
chr3_-_139480723 0.34 ENST00000511956.1
ENST00000506825.1
RBP2
retinol binding protein 2
chr14_-_100569780 0.33 ENST00000355173.7
BEGAIN
brain enriched guanylate kinase associated
chr12_+_20695553 0.33 ENST00000545102.1
SLCO1C1
solute carrier organic anion transporter family member 1C1
chr1_+_165895583 0.31 ENST00000470820.1
UCK2
uridine-cytidine kinase 2
chr8_+_103372388 0.31 ENST00000520337.1
CTHRC1
collagen triple helix repeat containing 1
chr21_+_38272291 0.31 ENST00000438657.5
KCNJ15
potassium inwardly rectifying channel subfamily J member 15
chr14_-_64942720 0.30 ENST00000557049.1
ENST00000389614.6
GPX2
glutathione peroxidase 2
chr10_+_89283685 0.30 ENST00000638108.1
IFIT2
interferon induced protein with tetratricopeptide repeats 2
chr20_+_46008900 0.30 ENST00000372330.3
MMP9
matrix metallopeptidase 9
chr19_-_10380454 0.29 ENST00000530829.1
ENST00000529370.5
TYK2
tyrosine kinase 2
chr15_+_22094522 0.29 ENST00000328795.5
OR4N4
olfactory receptor family 4 subfamily N member 4
chr19_+_44914833 0.29 ENST00000589078.1
ENST00000586638.5
APOC1
apolipoprotein C1
chr3_+_136819069 0.29 ENST00000393079.3
ENST00000446465.3
SLC35G2
solute carrier family 35 member G2
chr6_+_36871841 0.29 ENST00000359359.6
C6orf89
chromosome 6 open reading frame 89
chr17_+_3420568 0.28 ENST00000574571.4
OR3A3
olfactory receptor family 3 subfamily A member 3
chrM_-_14669 0.28 ENST00000361681.2
MT-ND6
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6
chr21_-_6467509 0.27 ENST00000624406.3
ENST00000398168.5
ENST00000624934.3
CBSL
cystathionine beta-synthase like
chrX_-_49184789 0.27 ENST00000453382.5
ENST00000432913.5
PRICKLE3
prickle planar cell polarity protein 3
chr4_-_174829212 0.27 ENST00000340217.5
ENST00000274093.8
GLRA3
glycine receptor alpha 3
chr1_+_111473972 0.26 ENST00000369718.4
C1orf162
chromosome 1 open reading frame 162
chr1_+_15153698 0.26 ENST00000400796.7
ENST00000376008.3
ENST00000434578.6
TMEM51
transmembrane protein 51
chr17_-_40994159 0.26 ENST00000391586.3
KRTAP3-3
keratin associated protein 3-3
chr2_-_165204042 0.26 ENST00000283254.12
ENST00000453007.1
SCN3A
sodium voltage-gated channel alpha subunit 3
chr12_-_64390727 0.26 ENST00000543942.7
C12orf56
chromosome 12 open reading frame 56
chr13_-_46182136 0.25 ENST00000323076.7
LCP1
lymphocyte cytosolic protein 1
chr14_-_24442765 0.25 ENST00000555365.5
ENST00000399395.8
ENST00000553930.5
SDR39U1
short chain dehydrogenase/reductase family 39U member 1
chr8_-_15238423 0.24 ENST00000382080.6
SGCZ
sarcoglycan zeta
chr17_+_47522931 0.24 ENST00000525007.5
ENST00000530173.6
NPEPPS
aminopeptidase puromycin sensitive
chr2_-_165953750 0.24 ENST00000243344.8
ENST00000679799.1
ENST00000679840.1
ENST00000681606.1
ENST00000680448.1
TTC21B
tetratricopeptide repeat domain 21B
chr19_-_43883964 0.24 ENST00000587539.2
ZNF404
zinc finger protein 404
chr16_+_3204247 0.23 ENST00000304646.2
OR1F1
olfactory receptor family 1 subfamily F member 1
chr15_+_21651844 0.23 ENST00000623441.1
OR4N4C
olfactory receptor family 4 subfamily N member 4C
chr6_-_26043704 0.23 ENST00000615966.2
H2BC3
H2B clustered histone 3
chr9_-_92536031 0.23 ENST00000344604.9
ENST00000375540.5
ECM2
extracellular matrix protein 2
chr19_-_3600581 0.22 ENST00000589966.1
TBXA2R
thromboxane A2 receptor
chr2_+_11534039 0.22 ENST00000381486.7
GREB1
growth regulating estrogen receptor binding 1
chr1_-_16431371 0.22 ENST00000612240.1
SPATA21
spermatogenesis associated 21
chr19_-_35228699 0.21 ENST00000324675.3
FAM187B
family with sequence similarity 187 member B
chr6_-_11044275 0.21 ENST00000354666.4
ELOVL2
ELOVL fatty acid elongase 2
chr5_-_64768619 0.21 ENST00000513458.9
SREK1IP1
SREK1 interacting protein 1
chr5_+_122845584 0.21 ENST00000395451.8
ENST00000261369.9
ENST00000506996.5
SNX24
sorting nexin 24
chr11_+_6926417 0.20 ENST00000610573.4
ENST00000278319.10
ZNF215
zinc finger protein 215
chr19_-_58573555 0.20 ENST00000599369.5
MZF1
myeloid zinc finger 1
chr2_+_29113989 0.19 ENST00000404424.5
CLIP4
CAP-Gly domain containing linker protein family member 4
chr13_+_52455429 0.19 ENST00000468284.1
ENST00000378034.7
ENST00000378037.9
ENST00000258607.10
CKAP2
cytoskeleton associated protein 2
chr17_+_79034185 0.18 ENST00000581774.5
C1QTNF1
C1q and TNF related 1
chr19_+_44914702 0.18 ENST00000592885.5
ENST00000589781.1
APOC1
apolipoprotein C1
chr20_-_35147285 0.18 ENST00000374491.3
ENST00000374492.8
EDEM2
ER degradation enhancing alpha-mannosidase like protein 2
chr19_-_46746421 0.18 ENST00000263280.11
STRN4
striatin 4
chr19_-_16496156 0.18 ENST00000269881.8
CALR3
calreticulin 3
chr14_-_24442662 0.18 ENST00000554698.5
SDR39U1
short chain dehydrogenase/reductase family 39U member 1
chr16_-_31135699 0.18 ENST00000317508.11
ENST00000568261.5
ENST00000567797.1
PRSS8
serine protease 8
chr3_-_33645433 0.17 ENST00000635664.1
ENST00000485378.6
ENST00000313350.10
ENST00000487200.5
CLASP2
cytoplasmic linker associated protein 2
chr19_+_44914588 0.17 ENST00000592535.6
APOC1
apolipoprotein C1
chr17_-_3398410 0.17 ENST00000322608.2
OR1E1
olfactory receptor family 1 subfamily E member 1
chr21_+_38272410 0.17 ENST00000398934.5
ENST00000398930.5
KCNJ15
potassium inwardly rectifying channel subfamily J member 15
chr1_-_243163310 0.17 ENST00000492145.1
ENST00000490813.5
ENST00000464936.5
CEP170
centrosomal protein 170
chr11_-_5324297 0.16 ENST00000624187.1
OR51B2
olfactory receptor family 51 subfamily B member 2
chr21_+_38272250 0.16 ENST00000398932.5
KCNJ15
potassium inwardly rectifying channel subfamily J member 15
chr14_+_22105305 0.16 ENST00000390453.1
TRAV24
T cell receptor alpha variable 24
chr1_+_207496147 0.16 ENST00000400960.7
ENST00000367049.9
CR1
complement C3b/C4b receptor 1 (Knops blood group)
chr3_-_88149815 0.15 ENST00000467332.1
ENST00000462901.5
CGGBP1
CGG triplet repeat binding protein 1
chr2_+_233778330 0.15 ENST00000389758.3
MROH2A
maestro heat like repeat family member 2A
chr2_-_135876382 0.15 ENST00000264156.3
MCM6
minichromosome maintenance complex component 6
chr17_-_40565459 0.15 ENST00000578085.1
ENST00000246657.2
CCR7
C-C motif chemokine receptor 7
chr17_+_56153458 0.15 ENST00000318698.6
ENST00000682825.1
ENST00000566473.6
ANKFN1
ankyrin repeat and fibronectin type III domain containing 1
chr2_-_240820945 0.14 ENST00000428768.2
ENST00000650053.1
ENST00000650130.1
KIF1A
kinesin family member 1A
chr1_-_51878799 0.14 ENST00000354831.11
ENST00000544028.5
NRDC
nardilysin convertase
chr19_+_13151975 0.13 ENST00000588173.1
IER2
immediate early response 2
chr2_-_222656067 0.13 ENST00000281828.8
FARSB
phenylalanyl-tRNA synthetase subunit beta
chr3_-_36739791 0.13 ENST00000416516.2
DCLK3
doublecortin like kinase 3
chr12_-_10986912 0.13 ENST00000506868.1
TAS2R50
taste 2 receptor member 50
chr8_+_90940517 0.12 ENST00000521366.1
NECAB1
N-terminal EF-hand calcium binding protein 1
chr1_+_162497805 0.11 ENST00000538489.5
ENST00000489294.2
UHMK1
U2AF homology motif kinase 1
chr1_+_241652275 0.11 ENST00000366552.6
ENST00000437684.7
WDR64
WD repeat domain 64
chr22_+_24806265 0.11 ENST00000400359.4
SGSM1
small G protein signaling modulator 1
chr11_-_73876674 0.11 ENST00000545127.1
ENST00000537289.1
ENST00000355693.5
COA4
cytochrome c oxidase assembly factor 4 homolog
chr6_+_167111789 0.11 ENST00000400926.5
CCR6
C-C motif chemokine receptor 6
chr11_-_85665077 0.11 ENST00000527447.2
CREBZF
CREB/ATF bZIP transcription factor
chr1_+_207496229 0.10 ENST00000367051.6
ENST00000367053.6
ENST00000367052.6
CR1
complement C3b/C4b receptor 1 (Knops blood group)
chr8_-_16186270 0.10 ENST00000445506.6
MSR1
macrophage scavenger receptor 1
chr12_-_75209701 0.10 ENST00000350228.6
ENST00000298972.5
KCNC2
potassium voltage-gated channel subfamily C member 2
chr1_-_51990679 0.09 ENST00000371655.4
RAB3B
RAB3B, member RAS oncogene family
chr7_+_149872955 0.09 ENST00000421974.7
ENST00000456496.7
ATP6V0E2
ATPase H+ transporting V0 subunit e2
chr12_-_6470643 0.09 ENST00000535180.5
ENST00000400911.7
VAMP1
vesicle associated membrane protein 1
chrM_+_4467 0.08 ENST00000361453.3
MT-ND2
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2
chr16_+_32066065 0.08 ENST00000354689.6
IGHV3OR16-9
immunoglobulin heavy variable 3/OR16-9 (non-functional)
chrX_+_71283577 0.08 ENST00000420903.6
ENST00000373856.8
ENST00000678437.1
ENST00000678830.1
ENST00000677879.1
ENST00000373841.5
ENST00000276079.13
ENST00000676797.1
ENST00000678660.1
ENST00000678231.1
ENST00000677612.1
ENST00000413858.5
ENST00000450092.6
NONO
non-POU domain containing octamer binding
chr1_+_209938207 0.08 ENST00000472886.5
SYT14
synaptotagmin 14
chr2_+_113437691 0.08 ENST00000259199.9
ENST00000416503.6
ENST00000433343.6
CBWD2
COBW domain containing 2
chr2_+_1413456 0.08 ENST00000539820.5
ENST00000382269.7
ENST00000345913.8
ENST00000329066.9
ENST00000382201.7
TPO
thyroid peroxidase
chr9_-_4666347 0.08 ENST00000381890.9
ENST00000682582.1
SPATA6L
spermatogenesis associated 6 like
chrX_-_49080066 0.08 ENST00000634944.1
ENST00000423215.3
ENST00000465382.6
WDR45
WD repeat domain 45
chr12_-_11269696 0.07 ENST00000381842.7
PRB3
proline rich protein BstNI subfamily 3
chr11_-_117098415 0.07 ENST00000445177.6
ENST00000375300.6
ENST00000446921.6
SIK3
SIK family kinase 3
chr15_+_51751587 0.07 ENST00000539962.6
ENST00000249700.9
TMOD2
tropomodulin 2
chr4_-_75724362 0.07 ENST00000677583.1
G3BP2
G3BP stress granule assembly factor 2
chr1_-_35031905 0.07 ENST00000317538.9
ENST00000357182.9
ZMYM6
zinc finger MYM-type containing 6
chr12_-_62192762 0.07 ENST00000416284.8
TAFA2
TAFA chemokine like family member 2
chr6_+_26538338 0.07 ENST00000377575.3
HMGN4
high mobility group nucleosomal binding domain 4
chr4_+_70721953 0.07 ENST00000381006.8
ENST00000226328.8
RUFY3
RUN and FYVE domain containing 3
chr9_+_105662457 0.07 ENST00000334077.6
TAL2
TAL bHLH transcription factor 2
chr9_-_110999458 0.06 ENST00000374430.6
LPAR1
lysophosphatidic acid receptor 1
chr16_+_50025217 0.06 ENST00000427478.7
CNEP1R1
CTD nuclear envelope phosphatase 1 regulatory subunit 1
chr10_-_45535346 0.06 ENST00000453424.7
ENST00000395769.6
MARCHF8
membrane associated ring-CH-type finger 8
chr1_+_209938169 0.06 ENST00000367019.5
ENST00000537238.5
ENST00000637265.1
SYT14
synaptotagmin 14
chr9_-_101435760 0.06 ENST00000647789.2
ENST00000616752.1
ALDOB
aldolase, fructose-bisphosphate B
chr1_-_85708382 0.05 ENST00000370574.4
ENST00000431532.6
ZNHIT6
zinc finger HIT-type containing 6
chr19_+_16496383 0.05 ENST00000594035.5
ENST00000221671.8
ENST00000599550.1
ENST00000594813.1
C19orf44
chromosome 19 open reading frame 44
chr17_+_38297023 0.05 ENST00000619548.1
ENST00000613675.5
MRPL45
mitochondrial ribosomal protein L45
chr7_+_20647343 0.05 ENST00000443026.6
ENST00000406935.5
ABCB5
ATP binding cassette subfamily B member 5
chr6_+_10694916 0.05 ENST00000379568.4
PAK1IP1
PAK1 interacting protein 1
chr8_+_103298433 0.05 ENST00000522566.5
FZD6
frizzled class receptor 6
chr7_-_105522264 0.05 ENST00000469408.6
PUS7
pseudouridine synthase 7
chr3_+_189789672 0.05 ENST00000434928.5
TP63
tumor protein p63
chr13_-_26221703 0.05 ENST00000381570.7
ENST00000346166.7
RNF6
ring finger protein 6
chr11_+_18172837 0.05 ENST00000314254.3
MRGPRX4
MAS related GPR family member X4
chr7_-_15561986 0.05 ENST00000342526.8
AGMO
alkylglycerol monooxygenase
chr13_-_48413105 0.04 ENST00000620633.5
LPAR6
lysophosphatidic acid receptor 6
chr6_-_39322688 0.04 ENST00000437525.3
KCNK16
potassium two pore domain channel subfamily K member 16
chr2_+_165294031 0.04 ENST00000283256.10
SCN2A
sodium voltage-gated channel alpha subunit 2
chr3_+_141262614 0.04 ENST00000504264.5
PXYLP1
2-phosphoxylose phosphatase 1
chr4_-_65670339 0.04 ENST00000273854.7
EPHA5
EPH receptor A5
chr6_-_170553216 0.03 ENST00000262193.7
PSMB1
proteasome 20S subunit beta 1
chr1_-_149861210 0.03 ENST00000579512.2
H4C15
H4 clustered histone 15
chr8_+_24384275 0.03 ENST00000256412.8
ADAMDEC1
ADAM like decysin 1
chr1_-_21783134 0.03 ENST00000308271.14
USP48
ubiquitin specific peptidase 48
chr1_-_51878711 0.03 ENST00000352171.12
NRDC
nardilysin convertase
chr4_-_65670478 0.02 ENST00000613740.5
ENST00000622150.4
ENST00000511294.1
EPHA5
EPH receptor A5
chr4_+_15339818 0.02 ENST00000397700.6
ENST00000295297.4
C1QTNF7
C1q and TNF related 7
chr17_+_63484840 0.02 ENST00000290863.10
ENST00000413513.7
ACE
angiotensin I converting enzyme
chrX_-_153926254 0.01 ENST00000393721.5
ENST00000370028.7
ENST00000350060.10
ARHGAP4
Rho GTPase activating protein 4
chr12_-_6470667 0.01 ENST00000361716.8
ENST00000396308.4
VAMP1
vesicle associated membrane protein 1
chr3_-_126558926 0.01 ENST00000318225.3
C3orf22
chromosome 3 open reading frame 22
chrX_-_140784366 0.01 ENST00000674533.1
CDR1
cerebellar degeneration related protein 1
chr1_-_11796536 0.01 ENST00000641820.1
MTHFR
methylenetetrahydrofolate reductase
chr11_+_65027402 0.01 ENST00000377244.8
ENST00000534637.5
ENST00000524831.5
SNX15
sorting nexin 15
chr4_-_47463649 0.00 ENST00000381571.6
COMMD8
COMM domain containing 8

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.2 0.6 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 0.5 GO:0018874 benzoate metabolic process(GO:0018874)
0.2 0.9 GO:0030070 insulin processing(GO:0030070)
0.2 0.7 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.2 0.6 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.1 1.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.5 GO:0090096 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.1 0.5 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.1 0.5 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.3 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.1 0.2 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.1 0.6 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 0.2 GO:0036510 trimming of terminal mannose on C branch(GO:0036510)
0.1 0.2 GO:2000547 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) regulation of dendritic cell dendrite assembly(GO:2000547)
0.1 0.7 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 1.4 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.4 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:0030451 regulation of complement activation, alternative pathway(GO:0030451) negative regulation of complement activation, alternative pathway(GO:0045957)
0.0 0.3 GO:0006535 cysteine biosynthetic process from serine(GO:0006535)
0.0 0.3 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.3 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.0 0.3 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.2 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.3 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.2 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.4 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.1 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.4 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:0051586 peptidyl-cysteine methylation(GO:0018125) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0 0.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.3 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.3 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.2 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.4 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:0048058 compound eye corneal lens development(GO:0048058)
0.0 0.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.1 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.0 0.1 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.0 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.0 0.2 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.4 GO:0000732 strand displacement(GO:0000732)
0.0 0.1 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.1 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.8 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.6 GO:0010107 potassium ion import(GO:0010107)
0.0 0.5 GO:0019433 triglyceride catabolic process(GO:0019433)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0005588 collagen type V trimer(GO:0005588)
0.1 1.1 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.7 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 3.9 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.5 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.6 GO:0042627 chylomicron(GO:0042627)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.1 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.1 0.4 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 0.5 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.4 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 0.2 GO:0070052 collagen V binding(GO:0070052)
0.1 0.2 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.1 0.6 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.1 0.7 GO:0004075 biotin carboxylase activity(GO:0004075)
0.1 0.5 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 0.3 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 1.1 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.1 GO:0001861 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
0.0 0.3 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.0 0.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.9 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 1.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.6 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.3 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 1.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.6 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.4 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.2 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.2 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0016918 retinal binding(GO:0016918) retinol binding(GO:0019841)
0.0 0.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 2.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.8 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 1.4 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.1 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.6 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.6 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.4 REACTOME OPSINS Genes involved in Opsins
0.0 0.7 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 1.1 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 3.7 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.1 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.7 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis