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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for ALX1_ARX

Z-value: 0.46

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Transcription factors associated with ALX1_ARX

Gene Symbol Gene ID Gene Info
ALX1
ENSG00000180318.4 ALX1
ARX
ENSG00000004848.8 ARX

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ARXhg38_v1_chrX_-_25015924_25016002-0.422.1e-02Click!
ALX1hg38_v1_chr12_+_85280199_852802370.019.6e-01Click!

Activity profile of ALX1_ARX motif

Sorted Z-values of ALX1_ARX motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ALX1_ARX

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr4_+_68447453 1.47 ENST00000305363.9
TMPRSS11E
transmembrane serine protease 11E
chr6_+_34236865 1.09 ENST00000674029.1
ENST00000447654.5
ENST00000347617.10
ENST00000401473.7
ENST00000311487.9
HMGA1
high mobility group AT-hook 1
chr6_-_65707214 0.94 ENST00000370621.7
ENST00000393380.6
ENST00000503581.6
EYS
eyes shut homolog
chr14_+_23630109 0.81 ENST00000432832.6
DHRS2
dehydrogenase/reductase 2
chr6_+_121437378 0.78 ENST00000650427.1
ENST00000647564.1
GJA1
gap junction protein alpha 1
chr9_+_72577939 0.77 ENST00000645773.1
TMC1
transmembrane channel like 1
chr2_-_31217511 0.76 ENST00000403897.4
CAPN14
calpain 14
chr1_+_84164962 0.75 ENST00000614872.4
ENST00000394839.6
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr8_-_90082871 0.69 ENST00000265431.7
CALB1
calbindin 1
chr3_+_172754457 0.69 ENST00000441497.6
ECT2
epithelial cell transforming 2
chr1_+_50103903 0.68 ENST00000371827.5
ELAVL4
ELAV like RNA binding protein 4
chr2_-_55334529 0.61 ENST00000645860.1
ENST00000642563.1
ENST00000647396.1
CCDC88A
coiled-coil domain containing 88A
chr5_-_39270623 0.55 ENST00000512138.1
ENST00000646045.2
FYB1
FYN binding protein 1
chr3_-_142029108 0.55 ENST00000497579.5
TFDP2
transcription factor Dp-2
chr9_+_121567057 0.55 ENST00000394340.7
ENST00000436835.5
ENST00000259371.6
DAB2IP
DAB2 interacting protein
chr4_+_168092530 0.54 ENST00000359299.8
ANXA10
annexin A10
chr1_-_93681829 0.51 ENST00000260502.11
BCAR3
BCAR3 adaptor protein, NSP family member
chr12_-_89352395 0.50 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chr17_-_62808339 0.49 ENST00000583600.5
MARCHF10
membrane associated ring-CH-type finger 10
chr17_-_62808299 0.48 ENST00000311269.10
MARCHF10
membrane associated ring-CH-type finger 10
chr2_+_227813834 0.47 ENST00000358813.5
ENST00000409189.7
CCL20
C-C motif chemokine ligand 20
chr12_-_89352487 0.47 ENST00000548755.1
ENST00000279488.8
DUSP6
dual specificity phosphatase 6
chr1_+_84181630 0.46 ENST00000610457.1
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr12_-_118359639 0.45 ENST00000541786.5
ENST00000419821.6
ENST00000541878.5
TAOK3
TAO kinase 3
chr12_+_59689337 0.44 ENST00000261187.8
SLC16A7
solute carrier family 16 member 7
chr9_+_72577369 0.43 ENST00000651183.1
TMC1
transmembrane channel like 1
chr7_-_111392915 0.43 ENST00000450877.5
IMMP2L
inner mitochondrial membrane peptidase subunit 2
chr1_+_154429315 0.42 ENST00000476006.5
IL6R
interleukin 6 receptor
chrX_+_108045050 0.39 ENST00000458383.1
ENST00000217957.10
VSIG1
V-set and immunoglobulin domain containing 1
chrX_+_108044967 0.39 ENST00000415430.7
VSIG1
V-set and immunoglobulin domain containing 1
chr9_+_72577788 0.37 ENST00000645208.2
TMC1
transmembrane channel like 1
chrX_+_11293411 0.36 ENST00000348912.4
ENST00000380714.7
ENST00000380712.7
AMELX
amelogenin X-linked
chr10_-_29634964 0.36 ENST00000375398.6
ENST00000355867.8
SVIL
supervillin
chr6_-_132659178 0.36 ENST00000275216.3
TAAR1
trace amine associated receptor 1
chr19_+_7030578 0.36 ENST00000329753.5
MBD3L5
methyl-CpG binding domain protein 3 like 5
chr19_-_7021431 0.35 ENST00000636986.2
ENST00000637800.1
MBD3L2B
methyl-CpG binding domain protein 3 like 2B
chr19_-_6393205 0.35 ENST00000595047.5
GTF2F1
general transcription factor IIF subunit 1
chr17_+_76467597 0.34 ENST00000392492.8
AANAT
aralkylamine N-acetyltransferase
chr15_+_41774459 0.32 ENST00000457542.7
ENST00000456763.6
MAPKBP1
mitogen-activated protein kinase binding protein 1
chr11_+_66011994 0.32 ENST00000312134.3
CST6
cystatin E/M
chr19_-_6393131 0.32 ENST00000394456.10
GTF2F1
general transcription factor IIF subunit 1
chr17_-_41118369 0.31 ENST00000391413.4
KRTAP4-11
keratin associated protein 4-11
chr18_+_616672 0.30 ENST00000338387.11
CLUL1
clusterin like 1
chr3_-_125055987 0.30 ENST00000311127.9
HEG1
heart development protein with EGF like domains 1
chr18_+_616711 0.30 ENST00000579494.1
CLUL1
clusterin like 1
chr6_+_26199509 0.29 ENST00000356530.5
H2BC7
H2B clustered histone 7
chr18_-_63644250 0.29 ENST00000341074.10
ENST00000436264.1
SERPINB4
serpin family B member 4
chr6_+_63521738 0.26 ENST00000648894.1
ENST00000639568.2
PTP4A1
protein tyrosine phosphatase 4A1
chr4_-_103019634 0.26 ENST00000510559.1
ENST00000296422.12
ENST00000394789.7
SLC9B1
solute carrier family 9 member B1
chr2_+_233691607 0.26 ENST00000373424.5
ENST00000441351.1
UGT1A6
UDP glucuronosyltransferase family 1 member A6
chr5_+_148312416 0.25 ENST00000274565.5
SPINK7
serine peptidase inhibitor Kazal type 7
chr14_-_94770102 0.25 ENST00000238558.5
GSC
goosecoid homeobox
chr19_-_43465596 0.25 ENST00000244333.4
LYPD3
LY6/PLAUR domain containing 3
chr4_+_118034480 0.24 ENST00000296499.6
NDST3
N-deacetylase and N-sulfotransferase 3
chr18_+_10471829 0.24 ENST00000584596.2
APCDD1
APC down-regulated 1
chr3_-_98523013 0.23 ENST00000394181.6
ENST00000508902.5
ENST00000394180.6
CLDND1
claudin domain containing 1
chrY_-_6874027 0.23 ENST00000215479.10
AMELY
amelogenin Y-linked
chr4_-_89029881 0.23 ENST00000506913.1
FAM13A
family with sequence similarity 13 member A
chr11_+_55811367 0.23 ENST00000625203.2
OR5L1
olfactory receptor family 5 subfamily L member 1
chr14_-_80959484 0.22 ENST00000555529.5
ENST00000556042.5
ENST00000556981.5
CEP128
centrosomal protein 128
chr9_-_27005659 0.21 ENST00000380055.6
LRRC19
leucine rich repeat containing 19
chr3_-_33645433 0.21 ENST00000635664.1
ENST00000485378.6
ENST00000313350.10
ENST00000487200.5
CLASP2
cytoplasmic linker associated protein 2
chr3_+_122055355 0.21 ENST00000330540.7
ENST00000469710.5
ENST00000493101.5
CD86
CD86 molecule
chrX_-_11265975 0.21 ENST00000303025.10
ENST00000657361.1
ARHGAP6
Rho GTPase activating protein 6
chr18_+_63775369 0.21 ENST00000540675.5
SERPINB7
serpin family B member 7
chr4_-_142305935 0.21 ENST00000511838.5
INPP4B
inositol polyphosphate-4-phosphatase type II B
chr8_-_61689768 0.19 ENST00000517847.6
ENST00000389204.8
ENST00000517661.5
ENST00000517903.5
ENST00000522603.5
ENST00000541428.5
ENST00000522349.5
ENST00000522835.5
ENST00000518306.5
ASPH
aspartate beta-hydroxylase
chr8_-_10655137 0.19 ENST00000382483.4
RP1L1
RP1 like 1
chr12_-_91153149 0.19 ENST00000550758.1
DCN
decorin
chr3_+_130850585 0.19 ENST00000505330.5
ENST00000504381.5
ENST00000507488.6
ATP2C1
ATPase secretory pathway Ca2+ transporting 1
chr1_-_110391041 0.18 ENST00000369781.8
ENST00000437429.6
ENST00000541986.5
SLC16A4
solute carrier family 16 member 4
chr1_-_21050952 0.18 ENST00000264211.12
EIF4G3
eukaryotic translation initiation factor 4 gamma 3
chr12_-_11134644 0.18 ENST00000539585.1
TAS2R30
taste 2 receptor member 30
chr1_+_15341744 0.18 ENST00000444385.5
FHAD1
forkhead associated phosphopeptide binding domain 1
chr5_+_36151989 0.17 ENST00000274254.9
SKP2
S-phase kinase associated protein 2
chr22_-_28306645 0.17 ENST00000612946.4
TTC28
tetratricopeptide repeat domain 28
chr7_+_107583919 0.17 ENST00000491150.5
BCAP29
B cell receptor associated protein 29
chr3_-_142028597 0.17 ENST00000467667.5
TFDP2
transcription factor Dp-2
chrX_+_120604199 0.17 ENST00000371315.3
MCTS1
MCTS1 re-initiation and release factor
chr2_+_54456311 0.17 ENST00000615901.4
ENST00000356805.9
SPTBN1
spectrin beta, non-erythrocytic 1
chr9_+_74615582 0.16 ENST00000396204.2
RORB
RAR related orphan receptor B
chr11_+_89924064 0.16 ENST00000623787.3
TRIM49D2
tripartite motif containing 49D2
chr12_-_68225806 0.16 ENST00000229134.5
IL26
interleukin 26
chr21_+_46635595 0.16 ENST00000451211.6
ENST00000458387.6
ENST00000397638.6
ENST00000291705.11
ENST00000397637.5
ENST00000334494.8
ENST00000397628.5
ENST00000355680.8
ENST00000440086.5
PRMT2
protein arginine methyltransferase 2
chr6_+_26087417 0.15 ENST00000357618.10
ENST00000309234.10
HFE
homeostatic iron regulator
chr12_-_66803980 0.15 ENST00000539540.5
ENST00000540433.5
ENST00000541947.1
ENST00000538373.1
GRIP1
glutamate receptor interacting protein 1
chr14_-_81427390 0.15 ENST00000555447.5
STON2
stonin 2
chr11_+_121102666 0.15 ENST00000264037.2
TECTA
tectorin alpha
chr1_-_178871060 0.15 ENST00000234816.7
ANGPTL1
angiopoietin like 1
chrX_+_120604084 0.14 ENST00000371317.10
MCTS1
MCTS1 re-initiation and release factor
chr12_+_18261511 0.14 ENST00000538779.6
ENST00000433979.6
PIK3C2G
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr7_-_14841267 0.14 ENST00000406247.7
ENST00000399322.7
DGKB
diacylglycerol kinase beta
chr5_+_36152077 0.14 ENST00000546211.6
ENST00000620197.5
ENST00000678270.1
ENST00000679015.1
ENST00000678580.1
ENST00000274255.11
ENST00000508514.5
SKP2
S-phase kinase associated protein 2
chr11_-_4288083 0.14 ENST00000638166.1
SSU72P4
SSU72 pseudogene 4
chr3_-_47892743 0.14 ENST00000420772.6
MAP4
microtubule associated protein 4
chr1_+_192158448 0.14 ENST00000367460.4
RGS18
regulator of G protein signaling 18
chr3_+_12287899 0.13 ENST00000643888.2
PPARG
peroxisome proliferator activated receptor gamma
chr5_+_146447304 0.13 ENST00000296702.9
ENST00000394421.7
ENST00000679501.2
TCERG1
transcription elongation regulator 1
chr12_-_10172117 0.13 ENST00000545927.5
ENST00000309539.8
ENST00000432556.6
ENST00000544577.5
OLR1
oxidized low density lipoprotein receptor 1
chr6_-_27867581 0.13 ENST00000331442.5
H1-5
H1.5 linker histone, cluster member
chr1_+_186828941 0.13 ENST00000367466.4
PLA2G4A
phospholipase A2 group IVA
chr17_-_41168219 0.13 ENST00000391356.4
KRTAP4-3
keratin associated protein 4-3
chr12_-_110499546 0.13 ENST00000552130.6
VPS29
VPS29 retromer complex component
chr10_-_110304894 0.13 ENST00000369603.10
SMNDC1
survival motor neuron domain containing 1
chr17_-_40867200 0.13 ENST00000647902.1
ENST00000251643.5
KRT12
keratin 12
chr13_-_101416441 0.12 ENST00000675332.1
ENST00000676315.1
ENST00000251127.11
NALCN
sodium leak channel, non-selective
chrX_-_41665766 0.12 ENST00000643043.2
ENST00000486402.1
ENST00000646087.2
CASK
calcium/calmodulin dependent serine protein kinase
chr4_+_87832917 0.12 ENST00000395102.8
ENST00000497649.6
ENST00000540395.1
ENST00000560249.5
ENST00000511670.5
ENST00000361056.3
MEPE
matrix extracellular phosphoglycoprotein
chr7_+_136868622 0.12 ENST00000680005.1
ENST00000445907.6
CHRM2
cholinergic receptor muscarinic 2
chr11_-_72244166 0.12 ENST00000298231.5
PHOX2A
paired like homeobox 2A
chr9_-_92536031 0.12 ENST00000344604.9
ENST00000375540.5
ECM2
extracellular matrix protein 2
chr4_+_108650644 0.12 ENST00000512478.2
OSTC
oligosaccharyltransferase complex non-catalytic subunit
chr12_-_6635938 0.11 ENST00000329858.9
LPAR5
lysophosphatidic acid receptor 5
chr6_-_99349647 0.11 ENST00000389677.6
FAXC
failed axon connections homolog, metaxin like GST domain containing
chr3_+_141262614 0.11 ENST00000504264.5
PXYLP1
2-phosphoxylose phosphatase 1
chr4_+_108650585 0.11 ENST00000613215.4
ENST00000361564.9
OSTC
oligosaccharyltransferase complex non-catalytic subunit
chr3_+_12287859 0.11 ENST00000309576.11
ENST00000397015.7
PPARG
peroxisome proliferator activated receptor gamma
chr3_-_196515315 0.11 ENST00000397537.3
SMCO1
single-pass membrane protein with coiled-coil domains 1
chrX_+_38352573 0.11 ENST00000039007.5
OTC
ornithine transcarbamylase
chr1_+_248095184 0.11 ENST00000358120.3
ENST00000641893.1
OR2L13
olfactory receptor family 2 subfamily L member 13
chr3_-_165078480 0.11 ENST00000264382.8
SI
sucrase-isomaltase
chr2_+_184598520 0.11 ENST00000302277.7
ZNF804A
zinc finger protein 804A
chr3_-_33718207 0.11 ENST00000359576.9
ENST00000682230.1
ENST00000399362.8
CLASP2
cytoplasmic linker associated protein 2
chr20_+_31547367 0.11 ENST00000394552.3
MCTS2P
MCTS family member 2, pseudogene
chr2_+_118942188 0.11 ENST00000327097.5
MARCO
macrophage receptor with collagenous structure
chr5_+_141338753 0.11 ENST00000528330.2
ENST00000394576.3
PCDHGA2
protocadherin gamma subfamily A, 2
chr11_-_4339244 0.10 ENST00000524542.2
SSU72P7
SSU72 pseudogene 7
chr3_+_69936629 0.10 ENST00000394348.2
ENST00000531774.1
MITF
melanocyte inducing transcription factor
chr3_-_87276462 0.10 ENST00000561167.5
ENST00000560656.1
POU1F1
POU class 1 homeobox 1
chr3_-_165196689 0.10 ENST00000241274.3
SLITRK3
SLIT and NTRK like family member 3
chr11_-_11353241 0.10 ENST00000528848.3
CSNK2A3
casein kinase 2 alpha 3
chr1_-_109613070 0.10 ENST00000351050.8
GNAT2
G protein subunit alpha transducin 2
chr9_-_28670285 0.10 ENST00000379992.6
ENST00000308675.5
ENST00000613945.3
LINGO2
leucine rich repeat and Ig domain containing 2
chr8_+_38820332 0.10 ENST00000518809.5
ENST00000520611.1
TACC1
transforming acidic coiled-coil containing protein 1
chr8_-_85341659 0.09 ENST00000522389.5
CA1
carbonic anhydrase 1
chr5_-_9630351 0.09 ENST00000382492.4
TAS2R1
taste 2 receptor member 1
chr18_-_5396265 0.09 ENST00000579951.2
EPB41L3
erythrocyte membrane protein band 4.1 like 3
chr2_+_161136901 0.09 ENST00000259075.6
ENST00000432002.5
TANK
TRAF family member associated NFKB activator
chr1_+_12857086 0.09 ENST00000240189.2
PRAMEF2
PRAME family member 2
chr4_+_155903688 0.09 ENST00000536354.3
TDO2
tryptophan 2,3-dioxygenase
chr12_-_111685720 0.08 ENST00000327551.6
BRAP
BRCA1 associated protein
chr1_-_178871022 0.08 ENST00000367629.1
ANGPTL1
angiopoietin like 1
chr12_-_118190510 0.08 ENST00000540561.5
ENST00000537952.1
ENST00000537822.1
TAOK3
TAO kinase 3
chr17_-_73232218 0.08 ENST00000583024.1
ENST00000403627.7
ENST00000405159.7
ENST00000581110.1
FAM104A
family with sequence similarity 104 member A
chr6_+_27824084 0.08 ENST00000355057.3
H4C11
H4 clustered histone 11
chr3_-_130746760 0.08 ENST00000356763.8
PIK3R4
phosphoinositide-3-kinase regulatory subunit 4
chr4_-_142305826 0.08 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase type II B
chr11_-_13496018 0.08 ENST00000529816.1
PTH
parathyroid hormone
chr11_+_18412292 0.08 ENST00000541669.6
ENST00000280704.8
LDHC
lactate dehydrogenase C
chr3_-_165196369 0.08 ENST00000475390.2
SLITRK3
SLIT and NTRK like family member 3
chr10_+_68106109 0.07 ENST00000540630.5
ENST00000354393.6
MYPN
myopalladin
chr2_-_55269038 0.07 ENST00000417363.5
ENST00000412530.1
ENST00000366137.6
ENST00000420637.5
MTIF2
mitochondrial translational initiation factor 2
chr1_+_186296267 0.07 ENST00000533951.5
ENST00000367482.8
ENST00000635041.1
ENST00000367483.8
ENST00000367485.4
ENST00000445192.7
PRG4
proteoglycan 4
chr3_-_39280021 0.07 ENST00000399220.3
CX3CR1
C-X3-C motif chemokine receptor 1
chr3_-_87276577 0.07 ENST00000344265.8
ENST00000350375.7
POU1F1
POU class 1 homeobox 1
chr5_+_141364153 0.07 ENST00000518069.2
PCDHGA5
protocadherin gamma subfamily A, 5
chr12_+_12725897 0.07 ENST00000326765.10
APOLD1
apolipoprotein L domain containing 1
chr5_+_40909490 0.07 ENST00000313164.10
C7
complement C7
chr5_+_141364231 0.07 ENST00000611914.1
PCDHGA5
protocadherin gamma subfamily A, 5
chr3_-_9249623 0.07 ENST00000383836.8
SRGAP3
SLIT-ROBO Rho GTPase activating protein 3
chr14_+_34993240 0.06 ENST00000677647.1
SRP54
signal recognition particle 54
chr18_-_13915531 0.06 ENST00000327606.4
MC2R
melanocortin 2 receptor
chr2_+_75646775 0.06 ENST00000393909.7
ENST00000358788.10
ENST00000409374.5
MRPL19
mitochondrial ribosomal protein L19
chr4_+_70195719 0.06 ENST00000683306.1
ODAM
odontogenic, ameloblast associated
chr3_+_160225409 0.06 ENST00000326474.5
C3orf80
chromosome 3 open reading frame 80
chr10_+_27532521 0.06 ENST00000683924.1
RAB18
RAB18, member RAS oncogene family
chr4_-_75724386 0.06 ENST00000677606.1
ENST00000678798.1
ENST00000677970.1
ENST00000677620.1
ENST00000679281.1
ENST00000677333.1
ENST00000676470.1
ENST00000499709.3
ENST00000511868.6
ENST00000678971.1
ENST00000677265.1
ENST00000677952.1
ENST00000678122.1
ENST00000678100.1
ENST00000678062.1
ENST00000676666.1
G3BP2
G3BP stress granule assembly factor 2
chr3_-_71360753 0.06 ENST00000648783.1
FOXP1
forkhead box P1
chr17_-_41098084 0.06 ENST00000318329.6
ENST00000333822.5
KRTAP4-8
keratin associated protein 4-8
chr1_+_177170916 0.06 ENST00000361539.5
BRINP2
BMP/retinoic acid inducible neural specific 2
chr5_+_173918216 0.05 ENST00000519467.1
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr3_+_111674654 0.05 ENST00000636933.1
ENST00000393934.7
ENST00000477665.2
PLCXD2
phosphatidylinositol specific phospholipase C X domain containing 2
chr6_+_132552693 0.05 ENST00000275200.1
TAAR8
trace amine associated receptor 8
chr12_-_57479552 0.05 ENST00000424809.6
ARHGAP9
Rho GTPase activating protein 9
chr18_+_68798065 0.05 ENST00000360242.9
CCDC102B
coiled-coil domain containing 102B
chr8_-_85341705 0.05 ENST00000517618.5
CA1
carbonic anhydrase 1
chr1_+_159008978 0.05 ENST00000447473.6
IFI16
interferon gamma inducible protein 16
chr1_+_247549002 0.05 ENST00000366488.5
GCSAML
germinal center associated signaling and motility like
chr2_+_36696790 0.05 ENST00000497382.5
ENST00000404084.5
ENST00000379241.7
ENST00000401530.5
VIT
vitrin
chr8_-_121641424 0.05 ENST00000303924.5
HAS2
hyaluronan synthase 2
chr10_-_49188380 0.05 ENST00000374153.7
ENST00000374148.1
ENST00000374151.7
TMEM273
transmembrane protein 273
chr4_+_154563003 0.05 ENST00000302068.9
ENST00000509493.1
FGB
fibrinogen beta chain
chr12_+_64497968 0.04 ENST00000676593.1
ENST00000677093.1
TBK1
ENSG00000288665.1
TANK binding kinase 1
novel transcript
chr6_+_30914329 0.04 ENST00000541562.6
VARS2
valyl-tRNA synthetase 2, mitochondrial
chr6_+_30914205 0.04 ENST00000672801.1
ENST00000321897.9
ENST00000625423.2
ENST00000676266.1
ENST00000428017.5
VARS2
valyl-tRNA synthetase 2, mitochondrial
chr4_+_94455245 0.04 ENST00000508216.5
ENST00000514743.5
PDLIM5
PDZ and LIM domain 5
chr3_-_142028617 0.04 ENST00000477292.5
ENST00000478006.5
ENST00000495310.5
ENST00000486111.5
TFDP2
transcription factor Dp-2
chr4_+_75724569 0.04 ENST00000514213.7
ENST00000264904.8
USO1
USO1 vesicle transport factor
chr12_-_7503744 0.04 ENST00000396620.7
ENST00000432237.3
CD163
CD163 molecule
chr5_+_137867868 0.04 ENST00000515645.1
MYOT
myotilin
chr4_+_87650277 0.04 ENST00000339673.11
ENST00000282479.8
DMP1
dentin matrix acidic phosphoprotein 1
chr2_-_182427014 0.04 ENST00000409365.5
ENST00000351439.9
PDE1A
phosphodiesterase 1A
chr11_+_85647958 0.04 ENST00000304511.7
ENST00000528105.5
TMEM126A
transmembrane protein 126A
chr12_-_57479848 0.04 ENST00000393791.8
ENST00000552249.1
ARHGAP9
Rho GTPase activating protein 9
chr11_+_95790459 0.03 ENST00000325486.9
ENST00000325542.10
ENST00000544522.5
ENST00000541365.5
CEP57
centrosomal protein 57
chr12_+_71686473 0.03 ENST00000549735.5
TMEM19
transmembrane protein 19
chr13_+_53028806 0.03 ENST00000219022.3
OLFM4
olfactomedin 4
chr4_-_82844418 0.03 ENST00000503937.5
SEC31A
SEC31 homolog A, COPII coat complex component
chr1_-_151175966 0.03 ENST00000441701.1
ENST00000295314.9
TMOD4
tropomodulin 4
chr5_+_141343818 0.03 ENST00000619750.1
ENST00000253812.8
PCDHGA3
protocadherin gamma subfamily A, 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.2 1.0 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.2 0.8 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.2 1.2 GO:0097338 response to clozapine(GO:0097338)
0.2 0.5 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.2 1.6 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.4 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.3 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1 0.4 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.6 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 0.3 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.3 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 0.5 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.1 0.7 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.1 0.2 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.1 0.3 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.2 GO:0043017 negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017)
0.1 0.4 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.1 0.1 GO:0021623 oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623)
0.1 0.4 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 0.3 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.1 0.2 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.2 GO:1900390 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.0 0.2 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.0 0.2 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.3 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.0 0.2 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.7 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.1 GO:0097272 ammonia homeostasis(GO:0097272)
0.0 1.0 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.2 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.8 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.7 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.8 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.1 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.0 0.2 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.3 GO:1900004 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.3 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.3 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.2 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.5 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.0 0.1 GO:0019249 lactate biosynthetic process(GO:0019249)
0.0 0.1 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.0 0.8 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.2 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.1 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.0 0.4 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.5 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.0 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.1 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.3 GO:0034505 tooth mineralization(GO:0034505)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 0.5 GO:1990032 parallel fiber(GO:1990032)
0.1 1.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.7 GO:0097149 centralspindlin complex(GO:0097149)
0.1 0.4 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 1.6 GO:0032426 stereocilium tip(GO:0032426)
0.1 0.4 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 1.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.2 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.4 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.8 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.2 GO:0032437 cuticular plate(GO:0032437)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.1 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.3 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.2 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.2 0.5 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.1 0.4 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.4 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.1 0.4 GO:0046848 hydroxyapatite binding(GO:0046848)
0.1 0.7 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.3 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.1 1.6 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 0.8 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.1 1.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.5 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 1.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 1.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.4 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.2 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.3 GO:0034597 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.7 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.2 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.2 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.6 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.1 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.1 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 0.7 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.1 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.2 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.4 ST STAT3 PATHWAY STAT3 Pathway
0.0 1.0 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.8 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.1 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.5 PID RAS PATHWAY Regulation of Ras family activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 1.0 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.8 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 1.2 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.7 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation