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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for ATF5

Z-value: 1.01

Motif logo

Transcription factors associated with ATF5

Gene Symbol Gene ID Gene Info
ENSG00000169136.12 ATF5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ATF5hg38_v1_chr19_+_49928702_49928769-0.319.6e-02Click!

Activity profile of ATF5 motif

Sorted Z-values of ATF5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ATF5

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr5_-_39219555 4.33 ENST00000512982.4
ENST00000351578.12
ENST00000509072.5
ENST00000504542.1
ENST00000506557.5
FYN binding protein 1
chr1_-_16978276 3.56 ENST00000375534.7
microfibril associated protein 2
chr21_-_26843012 3.46 ENST00000517777.6
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr21_-_26843063 3.39 ENST00000678221.1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr2_-_112784486 3.13 ENST00000263339.4
interleukin 1 alpha
chr6_-_30686624 2.99 ENST00000274853.8
protein phosphatase 1 regulatory subunit 18
chr12_-_24949026 2.64 ENST00000539780.5
ENST00000546285.1
ENST00000342945.9
ENST00000261192.12
branched chain amino acid transaminase 1
chr6_+_43770707 2.61 ENST00000324450.11
ENST00000417285.7
ENST00000413642.8
ENST00000372055.9
ENST00000482630.7
ENST00000425836.7
ENST00000372064.9
ENST00000372077.8
ENST00000519767.5
vascular endothelial growth factor A
chr1_+_209686173 2.07 ENST00000615289.4
ENST00000367028.6
ENST00000261465.5
hydroxysteroid 11-beta dehydrogenase 1
chr2_-_25982471 1.98 ENST00000264712.8
kinesin family member 3C
chr12_+_53098846 1.89 ENST00000650247.1
ENST00000549628.1
insulin like growth factor binding protein 6
chr5_+_155013755 1.82 ENST00000435029.6
kinesin family member 4B
chr1_+_15756659 1.64 ENST00000375771.5
filamin binding LIM protein 1
chr17_-_7205116 1.62 ENST00000649520.1
ENST00000649186.1
discs large MAGUK scaffold protein 4
chr19_-_43781249 1.61 ENST00000615047.4
potassium calcium-activated channel subfamily N member 4
chr15_+_80441229 1.60 ENST00000533983.5
ENST00000527771.5
ENST00000525103.1
aryl hydrocarbon receptor nuclear translocator 2
chr19_-_43780957 1.59 ENST00000648319.1
potassium calcium-activated channel subfamily N member 4
chr11_+_124865425 1.59 ENST00000397801.6
roundabout guidance receptor 3
chr17_+_35587478 1.38 ENST00000618940.4
adaptor related protein complex 2 subunit beta 1
chr8_-_42207557 1.37 ENST00000220809.9
ENST00000429089.6
ENST00000519510.5
ENST00000429710.6
ENST00000524009.5
plasminogen activator, tissue type
chr12_-_71663827 1.33 ENST00000378743.9
ENST00000552037.1
zinc finger C3H1-type containing
chrX_-_110318062 1.19 ENST00000372059.6
ENST00000262844.10
AMMECR nuclear protein 1
chr21_-_43058941 1.10 ENST00000451248.5
ENST00000458223.5
cystathionine beta-synthase
chr8_-_130016395 1.09 ENST00000523509.5
CYFIP related Rac1 interactor B
chr16_-_72093557 1.08 ENST00000562153.5
thioredoxin like 4B
chr8_-_130016622 1.03 ENST00000518283.5
ENST00000519110.5
CYFIP related Rac1 interactor B
chr8_-_130016414 1.02 ENST00000401979.6
ENST00000517654.5
ENST00000522361.1
ENST00000518167.5
CYFIP related Rac1 interactor B
chr1_+_42463221 1.01 ENST00000654683.1
ENST00000667205.1
ENST00000655164.1
ENST00000657597.1
ENST00000667947.1
ENST00000668663.1
ENST00000660083.1
ENST00000655845.1
ENST00000671281.1
ENST00000664805.1
ENST00000654604.1
ENST00000655447.1
ENST00000661864.1
ENST00000665176.1
ENST00000670982.1
ENST00000668036.1
coiled-coil domain containing 30
chr6_-_87702221 0.98 ENST00000257787.6
akirin 2
chr4_+_76251694 0.98 ENST00000510328.5
ENST00000424749.7
ENST00000502320.2
ENST00000515604.5
family with sequence similarity 47 member E
FAM47E-STBD1 readthrough
chrX_+_132023580 0.97 ENST00000496850.1
serine/threonine kinase 26
chr14_+_70452161 0.97 ENST00000603540.2
ADAM metallopeptidase domain 21
chr15_+_63189554 0.96 ENST00000559006.1
ENST00000321437.9
RAB8B, member RAS oncogene family
chr7_+_150991087 0.96 ENST00000461406.5
nitric oxide synthase 3
chr12_+_56521990 0.94 ENST00000550726.5
ENST00000542360.1
RNA binding motif single stranded interacting protein 2
chr12_+_56521951 0.92 ENST00000552247.6
RNA binding motif single stranded interacting protein 2
chr20_+_63861498 0.91 ENST00000369916.5
abhydrolase domain containing 16B
chr22_-_35840577 0.90 ENST00000405409.6
RNA binding fox-1 homolog 2
chr17_-_43125300 0.90 ENST00000497488.1
ENST00000354071.7
ENST00000489037.1
ENST00000470026.5
ENST00000644555.1
ENST00000586385.5
ENST00000591534.5
ENST00000591849.5
BRCA1 DNA repair associated
chr4_-_159035226 0.87 ENST00000434826.3
chromosome 4 open reading frame 45
chr7_-_3043838 0.83 ENST00000356408.3
ENST00000396946.9
caspase recruitment domain family member 11
chr5_+_137867852 0.83 ENST00000421631.6
ENST00000239926.9
myotilin
chr20_+_59604527 0.82 ENST00000371015.6
phosphatase and actin regulator 3
chr1_+_206406377 0.82 ENST00000605476.5
SLIT-ROBO Rho GTPase activating protein 2
chrX_+_119399286 0.81 ENST00000217909.8
solute carrier family 25 member 43
chr2_-_187554351 0.81 ENST00000437725.5
ENST00000409676.5
ENST00000233156.9
ENST00000339091.8
ENST00000420747.1
tissue factor pathway inhibitor
chr22_-_35961623 0.80 ENST00000408983.2
RNA binding fox-1 homolog 2
chr22_-_35840218 0.79 ENST00000414461.6
ENST00000416721.6
ENST00000449924.6
ENST00000262829.11
ENST00000397305.3
RNA binding fox-1 homolog 2
chr14_+_49598910 0.79 ENST00000298288.11
leucine rich repeat protein 1
chr7_+_43764191 0.77 ENST00000424330.1
biliverdin reductase A
chr2_+_233692881 0.77 ENST00000305139.11
UDP glucuronosyltransferase family 1 member A6
chr14_+_49598761 0.77 ENST00000318317.8
leucine rich repeat protein 1
chr3_-_99850976 0.76 ENST00000487087.5
filamin A interacting protein 1 like
chr2_-_190062721 0.75 ENST00000260950.5
myostatin
chr7_-_42152396 0.73 ENST00000642432.1
ENST00000647255.1
ENST00000677288.1
GLI family zinc finger 3
chr12_+_56521798 0.69 ENST00000262031.10
RNA binding motif single stranded interacting protein 2
chr15_-_75579248 0.68 ENST00000306726.6
ENST00000618819.5
protein tyrosine phosphatase non-receptor type 9
chr4_+_143336762 0.68 ENST00000262995.8
GRB2 associated binding protein 1
chr12_+_32502114 0.68 ENST00000682739.1
ENST00000427716.7
ENST00000583694.2
FYVE, RhoGEF and PH domain containing 4
chr7_-_42152444 0.68 ENST00000479210.1
GLI family zinc finger 3
chr17_+_35587239 0.67 ENST00000621914.4
ENST00000621668.4
ENST00000616681.4
ENST00000612035.4
ENST00000610402.5
ENST00000614600.4
ENST00000590432.5
ENST00000612116.5
adaptor related protein complex 2 subunit beta 1
chr8_+_38820332 0.66 ENST00000518809.5
ENST00000520611.1
transforming acidic coiled-coil containing protein 1
chr11_-_117232033 0.66 ENST00000524507.6
ENST00000320934.8
ENST00000532301.5
ENST00000676339.1
ENST00000540028.5
proprotein convertase subtilisin/kexin type 7
chr18_-_34224871 0.65 ENST00000261592.10
nucleolar protein 4
chr3_+_38165484 0.65 ENST00000446845.5
ENST00000311806.8
oxidative stress responsive kinase 1
chr6_+_113857333 0.64 ENST00000612661.2
myristoylated alanine rich protein kinase C substrate
chrX_+_123184153 0.63 ENST00000616590.4
glutamate ionotropic receptor AMPA type subunit 3
chr19_+_48465837 0.63 ENST00000595676.1
novel protein
chr12_+_9971402 0.62 ENST00000304361.9
ENST00000396507.7
ENST00000434319.6
C-type lectin domain family 12 member A
chr9_+_2621766 0.61 ENST00000382100.8
very low density lipoprotein receptor
chr7_+_128758947 0.61 ENST00000493278.1
calumenin
chrX_-_155071064 0.60 ENST00000369484.8
ENST00000369476.8
C-X9-C motif containing 4
mature T cell proliferation 1
chrX_+_123184260 0.60 ENST00000620443.2
ENST00000622768.5
ENST00000611689.4
glutamate ionotropic receptor AMPA type subunit 3
chr4_+_133149307 0.57 ENST00000618019.1
protocadherin 10
chr12_-_54384687 0.55 ENST00000550120.1
ENST00000547210.5
ENST00000394313.7
zinc finger protein 385A
chr2_+_172860038 0.54 ENST00000538974.5
ENST00000540783.5
Rap guanine nucleotide exchange factor 4
chr14_+_79280056 0.54 ENST00000676811.1
neurexin 3
chr12_-_52573816 0.52 ENST00000549343.5
ENST00000305620.3
keratin 74
chr12_-_56449377 0.52 ENST00000229201.4
ENST00000553532.6
timeless circadian regulator
chr16_+_72093771 0.52 ENST00000268482.8
DEAH-box helicase 38
chr17_-_43125353 0.49 ENST00000476777.5
ENST00000491747.6
ENST00000478531.5
ENST00000357654.9
ENST00000477152.5
ENST00000618469.1
ENST00000352993.7
ENST00000493795.5
ENST00000493919.5
BRCA1 DNA repair associated
chr1_+_151766655 0.49 ENST00000400999.7
ornithine decarboxylase antizyme 3
chrX_-_129523436 0.48 ENST00000371123.5
ENST00000371121.5
ENST00000371122.8
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr11_+_118606428 0.47 ENST00000361417.6
pleckstrin homology like domain family B member 1
chr8_-_673547 0.47 ENST00000522893.1
glutamate rich 1
chr17_-_75153826 0.47 ENST00000481647.5
ENST00000470924.5
Jupiter microtubule associated homolog 1
chr14_+_23376765 0.46 ENST00000649278.1
CKLF like MARVEL transmembrane domain containing 5
chr12_+_32107296 0.46 ENST00000551086.1
BICD cargo adaptor 1
chr2_-_208254232 0.45 ENST00000415913.5
ENST00000415282.5
ENST00000446179.5
isocitrate dehydrogenase (NADP(+)) 1
chr17_-_49210567 0.45 ENST00000507680.6
G protein subunit gamma transducin 2
chr14_+_79280263 0.45 ENST00000555387.1
neurexin 3
chr1_+_202122881 0.45 ENST00000683302.1
ENST00000683557.1
G protein-coupled receptor 37 like 1
chr2_-_208129824 0.44 ENST00000282141.4
crystallin gamma C
chr9_-_68540879 0.44 ENST00000377311.4
transmembrane protein 252
chrX_+_132023294 0.44 ENST00000481105.5
ENST00000354719.10
ENST00000394334.7
ENST00000394335.6
serine/threonine kinase 26
chr2_-_208255055 0.43 ENST00000345146.7
isocitrate dehydrogenase (NADP(+)) 1
chr5_+_137867868 0.43 ENST00000515645.1
myotilin
chr14_+_79279681 0.42 ENST00000679122.1
neurexin 3
chr14_+_23376786 0.41 ENST00000359320.7
CKLF like MARVEL transmembrane domain containing 5
chr4_+_158521872 0.41 ENST00000307765.10
relaxin family peptide receptor 1
chr7_+_133253064 0.41 ENST00000393161.6
ENST00000253861.5
exocyst complex component 4
chr20_+_56412112 0.41 ENST00000360314.7
Cas scaffold protein family member 4
chr8_-_94436926 0.41 ENST00000481490.3
fibrinogen silencer binding protein
chr9_-_23826231 0.40 ENST00000397312.7
ELAV like RNA binding protein 2
chr14_-_36519679 0.40 ENST00000498187.6
NK2 homeobox 1
chr9_+_2622053 0.40 ENST00000681306.1
ENST00000681618.1
very low density lipoprotein receptor
chr14_+_23377001 0.40 ENST00000342473.8
ENST00000397227.7
ENST00000339180.9
ENST00000555731.5
CKLF like MARVEL transmembrane domain containing 5
chr14_-_23578756 0.40 ENST00000397118.7
ENST00000356300.9
junctophilin 4
chr17_-_48615261 0.40 ENST00000239144.5
homeobox B8
chr6_+_101181254 0.39 ENST00000682090.1
ENST00000421544.6
glutamate ionotropic receptor kainate type subunit 2
chr1_+_1512137 0.38 ENST00000378756.8
ENST00000378755.9
ATPase family AAA domain containing 3A
chr20_+_56412249 0.37 ENST00000679887.1
ENST00000434344.2
Cas scaffold protein family member 4
chr4_+_158521714 0.37 ENST00000613319.4
ENST00000423548.5
ENST00000448688.6
relaxin family peptide receptor 1
chr19_+_15049469 0.36 ENST00000427043.4
caspase 14
chr7_-_102592444 0.36 ENST00000514917.3
novel protein
chr5_+_83471736 0.36 ENST00000265077.8
versican
chr1_+_66534082 0.36 ENST00000683257.1
ENST00000684083.1
ENST00000682938.1
ENST00000683581.1
ENST00000682293.1
SH3GL interacting endocytic adaptor 1
chr1_-_26960413 0.36 ENST00000320567.6
keratinocyte differentiation factor 1
chr8_+_20197369 0.35 ENST00000276390.7
ENST00000519667.1
ATPase H+ transporting V1 subunit B2
chr16_+_30064142 0.35 ENST00000562168.5
ENST00000569545.5
aldolase, fructose-bisphosphate A
chr22_+_19131271 0.35 ENST00000399635.4
testis specific serine kinase 2
chr1_+_66534107 0.35 ENST00000371037.9
ENST00000684651.1
SH3GL interacting endocytic adaptor 1
chr5_-_149063021 0.34 ENST00000515425.6
SH3 domain and tetratricopeptide repeats 2
chr5_+_83471668 0.34 ENST00000342785.8
ENST00000343200.9
versican
chr17_-_43125450 0.34 ENST00000494123.5
ENST00000468300.5
ENST00000471181.7
ENST00000652672.1
BRCA1 DNA repair associated
chr11_-_6440980 0.34 ENST00000265983.8
ENST00000615166.1
hemopexin
chr18_-_812516 0.34 ENST00000584307.5
YES proto-oncogene 1, Src family tyrosine kinase
chr11_+_62728642 0.34 ENST00000532583.1
tetratricopeptide repeat domain 9C
chr7_-_116030735 0.33 ENST00000393485.5
transcription factor EC
chr2_-_128027273 0.33 ENST00000259235.7
ENST00000357702.9
ENST00000424298.5
Sin3A associated protein 130
chr5_+_83471764 0.33 ENST00000512590.6
ENST00000513960.5
ENST00000513984.5
versican
chr7_-_116030750 0.32 ENST00000265440.12
ENST00000320239.11
transcription factor EC
chr8_+_22605018 0.32 ENST00000389279.7
cell cycle and apoptosis regulator 2
chr5_-_135452318 0.32 ENST00000537858.2
TIFA inhibitor
chr20_+_59163810 0.32 ENST00000371030.4
zinc finger protein 831
chr1_+_66534171 0.31 ENST00000682762.1
ENST00000424320.6
SH3GL interacting endocytic adaptor 1
chr18_-_3845292 0.31 ENST00000400145.6
DLG associated protein 1
chr16_-_72093598 0.30 ENST00000268483.8
thioredoxin like 4B
chr2_-_86790900 0.29 ENST00000283635.8
CD8a molecule
chr19_-_54360949 0.29 ENST00000622064.1
leukocyte associated immunoglobulin like receptor 1
chr18_-_812230 0.29 ENST00000314574.5
YES proto-oncogene 1, Src family tyrosine kinase
chr2_-_113241779 0.29 ENST00000497038.6
paired box 8
chr6_-_99568713 0.28 ENST00000520371.5
cyclin C
chr12_-_114683590 0.28 ENST00000257566.7
T-box transcription factor 3
chr17_+_42853232 0.28 ENST00000617500.4
amine oxidase copper containing 3
chr2_-_100142575 0.28 ENST00000317233.8
ENST00000672204.1
ENST00000416492.5
ENST00000672857.1
ENST00000672756.2
AF4/FMR2 family member 3
chr1_+_66534014 0.28 ENST00000684664.1
ENST00000682416.1
ENST00000683499.1
SH3GL interacting endocytic adaptor 1
chr12_-_114684151 0.28 ENST00000349155.7
T-box transcription factor 3
chr12_+_32107151 0.27 ENST00000548411.5
BICD cargo adaptor 1
chr12_-_16608183 0.27 ENST00000354662.5
ENST00000538051.5
LIM domain only 3
chr16_-_72094371 0.27 ENST00000426362.6
thioredoxin like 4B
chr5_+_83471925 0.27 ENST00000502527.2
versican
chr12_-_110502065 0.26 ENST00000447578.6
ENST00000546588.1
ENST00000360579.11
ENST00000549578.6
ENST00000549970.5
VPS29 retromer complex component
chr1_+_66533948 0.25 ENST00000684178.1
SH3GL interacting endocytic adaptor 1
chr20_+_56412393 0.25 ENST00000679529.1
Cas scaffold protein family member 4
chr8_-_13276491 0.25 ENST00000512044.6
DLC1 Rho GTPase activating protein
chr16_+_28931942 0.25 ENST00000324662.8
ENST00000538922.8
CD19 molecule
chr12_-_54258275 0.25 ENST00000552562.1
chromobox 5
chr3_+_98166696 0.24 ENST00000641450.1
olfactory receptor family 5 subfamily H member 15
chr1_+_206203541 0.24 ENST00000573034.8
SLIT-ROBO Rho GTPase activating protein 2
chrX_+_120604199 0.24 ENST00000371315.3
MCTS1 re-initiation and release factor
chr1_+_63322558 0.24 ENST00000371116.4
forkhead box D3
chr5_+_80319997 0.23 ENST00000296739.6
spermatogenic leucine zipper 1
chr10_-_73655984 0.23 ENST00000394810.3
synaptopodin 2 like
chr1_-_206970457 0.23 ENST00000324852.9
ENST00000450945.3
ENST00000400962.8
Fc fragment of IgA and IgM receptor
chr8_+_22604632 0.22 ENST00000308511.8
ENST00000523801.5
ENST00000521301.5
cell cycle and apoptosis regulator 2
chr3_+_19947074 0.22 ENST00000273047.9
RAB5A, member RAS oncogene family
chr11_+_62728465 0.22 ENST00000316461.9
tetratricopeptide repeat domain 9C
chr4_+_83455962 0.21 ENST00000507019.5
mitochondrial ribosomal protein S18C
chr11_+_92224801 0.20 ENST00000525166.6
FAT atypical cadherin 3
chr11_-_64166102 0.20 ENST00000255681.7
ENST00000675777.1
mono-ADP ribosylhydrolase 1
chr19_-_38426162 0.19 ENST00000587738.2
ENST00000586305.5
RAS guanyl releasing protein 4
chr3_+_19947316 0.19 ENST00000422242.1
RAB5A, member RAS oncogene family
chr12_-_16608073 0.18 ENST00000441439.6
LIM domain only 3
chr17_-_40364722 0.18 ENST00000578689.2
gap junction protein delta 3
chrX_+_154144242 0.18 ENST00000369951.9
opsin 1, long wave sensitive
chr11_+_63888515 0.18 ENST00000509502.6
ENST00000512060.1
microtubule affinity regulating kinase 2
chr5_+_132673983 0.17 ENST00000622422.1
ENST00000231449.7
ENST00000350025.2
interleukin 4
chr2_-_113241683 0.17 ENST00000468980.3
paired box 8
chr19_-_38426195 0.17 ENST00000615439.5
ENST00000614135.4
ENST00000622174.4
ENST00000587753.5
ENST00000454404.6
ENST00000617966.4
ENST00000618320.4
ENST00000293062.13
ENST00000433821.6
ENST00000426920.6
RAS guanyl releasing protein 4
chr14_+_92323154 0.17 ENST00000532405.6
ENST00000676001.1
ENST00000531433.5
solute carrier family 24 member 4
chrX_+_154219756 0.16 ENST00000369929.8
opsin 1, medium wave sensitive 2
chr19_+_42269219 0.16 ENST00000681038.1
capicua transcriptional repressor
chrX_-_47629845 0.16 ENST00000469388.1
ENST00000396992.8
ENST00000377005.6
complement factor properdin
chr14_-_44507269 0.16 ENST00000340446.5
fibrous sheath CABYR binding protein
chr10_+_101354083 0.15 ENST00000408038.6
ENST00000370187.8
beta-transducin repeat containing E3 ubiquitin protein ligase
chrX_+_123961696 0.15 ENST00000371145.8
ENST00000371157.7
ENST00000371144.7
stromal antigen 2
chr17_-_48614628 0.14 ENST00000576562.1
homeobox B8
chr10_+_101354028 0.14 ENST00000393441.8
beta-transducin repeat containing E3 ubiquitin protein ligase
chr1_-_156490599 0.14 ENST00000360595.7
myocyte enhancer factor 2D
chr12_-_120446372 0.13 ENST00000546954.2
TP53 regulated inhibitor of apoptosis 1
chr2_-_127884860 0.13 ENST00000393001.1
AMMECR1 like
chrX_-_44542833 0.13 ENST00000378045.5
FUN14 domain containing 1
chr3_-_183427977 0.13 ENST00000473233.5
MCF.2 cell line derived transforming sequence-like 2
chr2_+_188974364 0.12 ENST00000304636.9
ENST00000317840.9
collagen type III alpha 1 chain
chr1_-_11803383 0.12 ENST00000641407.1
ENST00000376583.7
ENST00000423400.7
methylenetetrahydrofolate reductase
chr17_+_35147807 0.12 ENST00000394570.7
ENST00000268876.9
unc-45 myosin chaperone B
chr18_-_3845321 0.12 ENST00000539435.5
ENST00000400147.6
DLG associated protein 1
chr17_+_18858068 0.12 ENST00000536323.5
ENST00000419284.6
ENST00000412418.5
ENST00000575228.5
ENST00000268835.7
ENST00000575102.5
phosphoribosyl pyrophosphate synthetase associated protein 2
chr12_+_78036248 0.11 ENST00000644176.1
neuron navigator 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.6 1.7 GO:0070512 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.5 2.6 GO:0009099 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.5 3.6 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.5 1.4 GO:0060367 subpallium cell proliferation in forebrain(GO:0022012) lateral ganglionic eminence cell proliferation(GO:0022018) lambdoid suture morphogenesis(GO:0060366) sagittal suture morphogenesis(GO:0060367) anterior semicircular canal development(GO:0060873) lateral semicircular canal development(GO:0060875)
0.4 3.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.4 7.8 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.4 2.0 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.4 1.1 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363)
0.3 0.9 GO:0006097 glyoxylate cycle(GO:0006097)
0.2 2.5 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.2 3.2 GO:0046541 saliva secretion(GO:0046541)
0.2 0.6 GO:0060932 sinoatrial node cell development(GO:0060931) His-Purkinje system cell differentiation(GO:0060932)
0.2 1.1 GO:0006535 cysteine biosynthetic process from serine(GO:0006535) cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) homocysteine catabolic process(GO:0043418) L-cysteine metabolic process(GO:0046439)
0.2 1.6 GO:0016199 axon midline choice point recognition(GO:0016199)
0.2 0.7 GO:1900276 regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.2 0.7 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.2 0.5 GO:0015847 putrescine transport(GO:0015847)
0.2 1.0 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
0.2 0.8 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.1 0.5 GO:1902164 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) platelet alpha granule organization(GO:0070889) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 1.0 GO:0034436 glycoprotein transport(GO:0034436)
0.1 1.6 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.5 GO:2000612 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.1 1.8 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 0.3 GO:0098583 mastication(GO:0071626) learned vocalization behavior(GO:0098583)
0.1 1.6 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.1 0.8 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 2.1 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.1 0.2 GO:0071288 cellular response to mercury ion(GO:0071288)
0.1 1.1 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 0.8 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 0.3 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.1 0.8 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1 0.3 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.1 0.5 GO:0072719 cellular response to cisplatin(GO:0072719)
0.1 0.5 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1 0.8 GO:0070970 interleukin-2 secretion(GO:0070970)
0.1 0.2 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.3 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 1.9 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 0.4 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0 1.3 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.4 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.4 GO:0021759 globus pallidus development(GO:0021759)
0.0 1.4 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.4 GO:0021940 positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.0 1.4 GO:0030033 microvillus assembly(GO:0030033)
0.0 0.4 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.5 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 1.3 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 2.0 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.5 GO:1901978 positive regulation of cell cycle checkpoint(GO:1901978)
0.0 1.6 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.3 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.6 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0 0.4 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.2 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.5 GO:1904261 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.7 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.5 GO:0007625 grooming behavior(GO:0007625)
0.0 0.6 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 0.2 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.2 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 1.0 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 1.7 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.2 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.7 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.1 GO:0007512 adult heart development(GO:0007512)
0.0 0.3 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.4 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.1 GO:2001140 regulation of phospholipid transport(GO:2001138) positive regulation of phospholipid transport(GO:2001140)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.2 0.6 GO:0001674 female germ cell nucleus(GO:0001674)
0.2 0.5 GO:0044609 DBIRD complex(GO:0044609)
0.2 0.7 GO:0072517 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.2 1.9 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 3.6 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 3.6 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 1.1 GO:0044327 dendritic spine head(GO:0044327)
0.1 1.6 GO:0098839 postsynaptic density membrane(GO:0098839)
0.1 1.0 GO:0051286 cell tip(GO:0051286)
0.1 0.4 GO:0030314 junctional membrane complex(GO:0030314)
0.1 0.6 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 3.4 GO:0097542 ciliary tip(GO:0097542)
0.1 1.7 GO:0005682 U5 snRNP(GO:0005682)
0.1 0.3 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 0.4 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.4 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.5 GO:0016589 NURF complex(GO:0016589)
0.0 6.9 GO:0005604 basement membrane(GO:0005604)
0.0 1.1 GO:0042101 T cell receptor complex(GO:0042101)
0.0 1.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 3.0 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.4 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 1.8 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.5 GO:0045180 basal cortex(GO:0045180)
0.0 1.0 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 1.6 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.0 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 2.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.4 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.3 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.2 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.3 GO:0070822 Sin3-type complex(GO:0070822)
0.0 1.4 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 0.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.3 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.9 GO:0045095 keratin filament(GO:0045095)
0.0 1.2 GO:0005901 caveola(GO:0005901)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.5 2.6 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.5 2.6 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.3 3.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.3 0.9 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450) (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.3 1.1 GO:0050421 oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
0.3 1.0 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.2 1.6 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.2 0.8 GO:0004074 biliverdin reductase activity(GO:0004074)
0.2 0.5 GO:0015489 polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
0.2 1.0 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.2 1.9 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 3.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.4 GO:0036505 prosaposin receptor activity(GO:0036505)
0.1 1.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 1.6 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 1.6 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.7 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.1 0.5 GO:1990254 keratin filament binding(GO:1990254)
0.1 2.0 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 1.0 GO:0030911 TPR domain binding(GO:0030911)
0.1 0.3 GO:0052595 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.1 1.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 1.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 1.6 GO:0031005 filamin binding(GO:0031005)
0.1 0.5 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.1 1.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.8 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.7 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 7.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.5 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.2 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.4 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.3 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 1.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.4 GO:0009881 photoreceptor activity(GO:0009881)
0.0 2.0 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.2 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.0 0.8 GO:0001972 retinoic acid binding(GO:0001972)
0.0 1.3 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 1.7 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.9 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.4 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.4 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.3 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.6 GO:0005080 protein kinase C binding(GO:0005080)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.6 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 3.1 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 2.4 PID AURORA A PATHWAY Aurora A signaling
0.0 1.0 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 2.0 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 3.9 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.6 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 7.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.0 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.8 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.1 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 1.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.7 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.5 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.4 PID INSULIN PATHWAY Insulin Pathway
0.0 0.4 PID RAS PATHWAY Regulation of Ras family activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 3.3 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 3.8 REACTOME KINESINS Genes involved in Kinesins
0.1 2.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.9 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.7 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 3.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 2.1 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.6 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 1.0 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 2.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.6 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.4 REACTOME OPSINS Genes involved in Opsins
0.0 1.1 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.8 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.8 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.9 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.7 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.8 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.8 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 3.3 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.5 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling