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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for BACH1_NFE2_NFE2L2

Z-value: 0.69

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Transcription factors associated with BACH1_NFE2_NFE2L2

Gene Symbol Gene ID Gene Info
ENSG00000156273.16 BACH1
ENSG00000123405.14 NFE2
ENSG00000116044.16 NFE2L2

Activity-expression correlation:

Activity profile of BACH1_NFE2_NFE2L2 motif

Sorted Z-values of BACH1_NFE2_NFE2L2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of BACH1_NFE2_NFE2L2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr10_+_132066003 2.06 ENST00000657318.1
ENST00000666210.1
Janus kinase and microtubule interacting protein 3
chr10_+_132065937 2.03 ENST00000658847.1
ENST00000666974.1
Janus kinase and microtubule interacting protein 3
chr12_+_55681647 1.93 ENST00000614691.1
methyltransferase like 7B
chr12_+_55681711 1.89 ENST00000394252.4
methyltransferase like 7B
chr22_+_19479457 1.40 ENST00000407835.6
ENST00000455750.6
cell division cycle 45
chr1_+_206770764 0.80 ENST00000656872.2
ENST00000659997.2
interleukin 19
chr10_+_133087883 0.68 ENST00000392607.8
adhesion G protein-coupled receptor A1
chr17_+_32444379 0.61 ENST00000578213.5
ENST00000649012.1
ENST00000457654.6
ENST00000579451.1
ENST00000261712.8
proteasome 26S subunit, non-ATPase 11
chr8_+_74339566 0.60 ENST00000675376.1
ganglioside induced differentiation associated protein 1
chr10_-_125816510 0.56 ENST00000650587.1
uroporphyrinogen III synthase
chr1_-_235588959 0.53 ENST00000484517.2
G protein subunit gamma 4
chr14_-_23155302 0.52 ENST00000529705.6
solute carrier family 7 member 8
chr2_+_10123171 0.52 ENST00000615152.5
ribonucleotide reductase regulatory subunit M2
chr14_-_64942783 0.50 ENST00000612794.1
glutathione peroxidase 2
chr12_-_70788914 0.49 ENST00000342084.8
protein tyrosine phosphatase receptor type R
chr10_-_125816596 0.49 ENST00000368786.5
uroporphyrinogen III synthase
chr14_-_64942720 0.49 ENST00000557049.1
ENST00000389614.6
glutathione peroxidase 2
chrX_+_154542194 0.47 ENST00000618670.4
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
chr19_+_46303599 0.47 ENST00000300862.7
hypoxia inducible factor 3 subunit alpha
chr19_+_55836532 0.46 ENST00000301295.11
NLR family pyrin domain containing 4
chr19_+_50203607 0.42 ENST00000642316.2
ENST00000425460.6
ENST00000440075.6
ENST00000376970.6
ENST00000599920.5
myosin heavy chain 14
chr16_+_89921851 0.41 ENST00000554444.5
ENST00000556565.5
tubulin beta 3 class III
chr2_-_210315160 0.40 ENST00000352451.4
myosin light chain 1
chr16_-_69726506 0.40 ENST00000561500.5
ENST00000320623.10
ENST00000439109.6
ENST00000564043.1
ENST00000379046.6
ENST00000379047.7
NAD(P)H quinone dehydrogenase 1
chr14_+_58244821 0.40 ENST00000216455.9
ENST00000412908.6
ENST00000557508.5
proteasome 20S subunit alpha 3
chr18_+_158513 0.39 ENST00000400266.7
ENST00000580410.5
ENST00000261601.8
ENST00000383589.6
ubiquitin specific peptidase 14
chr4_+_4387078 0.38 ENST00000504171.1
neuronal vesicle trafficking associated 1
chr6_-_83431038 0.38 ENST00000369705.4
malic enzyme 1
chr3_-_170870033 0.36 ENST00000466674.5
ENST00000295830.13
ENST00000463836.1
ribosomal protein L22 like 1
chr1_-_150235972 0.34 ENST00000534220.1
acidic nuclear phosphoprotein 32 family member E
chr3_-_48016400 0.33 ENST00000434267.5
ENST00000683076.1
ENST00000633710.1
microtubule associated protein 4
chr4_+_4387039 0.32 ENST00000621129.4
neuronal vesicle trafficking associated 1
chr22_+_44677077 0.32 ENST00000403581.5
proline rich 5
chrX_-_73214793 0.31 ENST00000373517.4
nucleosome assembly protein 1 like 2
chr22_+_44677044 0.31 ENST00000006251.11
proline rich 5
chr5_-_138575359 0.31 ENST00000297185.9
ENST00000678300.1
ENST00000677425.1
ENST00000677064.1
ENST00000507115.6
heat shock protein family A (Hsp70) member 9
chr19_-_15934521 0.30 ENST00000402119.9
cytochrome P450 family 4 subfamily F member 11
chr6_+_86937500 0.30 ENST00000305344.7
5-hydroxytryptamine receptor 1E
chr22_+_44676808 0.29 ENST00000624862.3
proline rich 5
chr17_-_75154534 0.29 ENST00000356033.8
Jupiter microtubule associated homolog 1
chr15_-_82647960 0.29 ENST00000615198.4
cytoplasmic polyadenylation element binding protein 1
chr16_+_83953232 0.29 ENST00000565123.5
ENST00000393306.6
oxidative stress induced growth inhibitor 1
chr1_-_93909329 0.29 ENST00000370238.8
ENST00000615724.1
glutamate-cysteine ligase modifier subunit
chr22_+_22697789 0.28 ENST00000390306.2
immunoglobulin lambda variable 2-23
chr9_+_72577939 0.28 ENST00000645773.1
transmembrane channel like 1
chr14_+_21990357 0.28 ENST00000390444.1
T cell receptor alpha variable 16
chr17_-_15566276 0.27 ENST00000630868.1
CMT1A duplicated region transcript 1
chr2_-_219254558 0.27 ENST00000392088.6
tubulin alpha 4a
chr7_-_1160144 0.26 ENST00000397083.6
ENST00000401903.5
ENST00000316495.8
zinc finger AN1-type containing 2A
chr16_-_30113528 0.26 ENST00000406256.8
glycerophosphodiester phosphodiesterase domain containing 3
chr10_-_50279715 0.26 ENST00000395526.9
N-acylsphingosine amidohydrolase 2
chr17_-_40703744 0.26 ENST00000264651.3
keratin 24
chr18_+_31318144 0.25 ENST00000257192.5
desmoglein 1
chr19_-_15934853 0.25 ENST00000620614.4
ENST00000248041.12
cytochrome P450 family 4 subfamily F member 11
chr11_+_6845683 0.25 ENST00000299454.5
olfactory receptor family 10 subfamily A member 5
chr1_-_201023694 0.24 ENST00000332129.6
ENST00000422435.2
ENST00000461742.7
kinesin family member 21B
chr8_+_86098901 0.24 ENST00000285393.4
ATPase H+ transporting V0 subunit d2
chr14_-_106088573 0.24 ENST00000632099.1
immunoglobulin heavy variable 3-64D
chr22_+_22327298 0.24 ENST00000390291.2
immunoglobulin lambda variable 1-50 (non-functional)
chr9_-_110256466 0.24 ENST00000374515.9
ENST00000374517.6
thioredoxin
chr22_+_22357739 0.24 ENST00000390294.2
immunoglobulin lambda variable 1-47
chr3_+_46163465 0.23 ENST00000357422.2
C-C motif chemokine receptor 3
chr15_-_82571803 0.23 ENST00000617462.4
ENST00000618449.4
cytoplasmic polyadenylation element binding protein 1
chr21_+_32298945 0.22 ENST00000339944.4
melanocortin 2 receptor accessory protein
chr10_-_97292625 0.21 ENST00000466484.1
ENST00000358531.9
ENST00000358308.7
Rho GTPase activating protein 19
chr18_+_63970029 0.21 ENST00000353706.6
ENST00000542677.5
ENST00000397985.7
ENST00000636430.1
ENST00000397988.7
ENST00000448851.5
serpin family B member 8
chr19_-_58511981 0.21 ENST00000263093.7
ENST00000601355.1
solute carrier family 27 member 5
chr2_+_89851723 0.20 ENST00000429992.2
immunoglobulin kappa variable 2D-40
chr6_-_105137147 0.20 ENST00000314641.10
blood vessel epicardial substance
chr3_+_184319677 0.20 ENST00000441154.5
eukaryotic translation initiation factor 4 gamma 1
chr19_-_49155130 0.20 ENST00000595625.1
histidine rich calcium binding protein
chr1_+_173868076 0.20 ENST00000367704.5
zinc finger and BTB domain containing 37
chr2_-_88992903 0.20 ENST00000495489.1
immunoglobulin kappa variable 1-8
chr17_-_41612757 0.20 ENST00000301653.9
ENST00000593067.1
keratin 16
chr3_+_184320283 0.20 ENST00000428387.5
ENST00000434061.6
eukaryotic translation initiation factor 4 gamma 1
chr14_+_21749163 0.20 ENST00000390427.3
T cell receptor alpha variable 5
chr19_-_49155384 0.19 ENST00000252825.9
histidine rich calcium binding protein
chr4_-_993376 0.19 ENST00000398520.6
ENST00000398516.3
solute carrier family 26 member 1
chr17_-_4545065 0.18 ENST00000572759.1
MYB binding protein 1a
chr11_+_123590939 0.18 ENST00000646146.1
GRAM domain containing 1B
chr2_-_42764116 0.18 ENST00000378661.3
oxoeicosanoid receptor 1
chr22_+_22734577 0.18 ENST00000390310.3
immunoglobulin lambda variable 2-18
chr7_+_141764097 0.18 ENST00000247879.2
taste 2 receptor member 3
chr2_-_169031317 0.18 ENST00000650372.1
ATP binding cassette subfamily B member 11
chr17_-_78925376 0.18 ENST00000262768.11
TIMP metallopeptidase inhibitor 2
chr1_-_162868761 0.18 ENST00000367910.5
ENST00000367912.6
coiled-coil domain containing 190
chr15_-_76012390 0.18 ENST00000394907.8
neuregulin 4
chr17_-_10838075 0.18 ENST00000580256.3
ENST00000643787.1
phosphoinositide interacting regulator of transient receptor potential channels
novel transcript
chr11_-_123885627 0.17 ENST00000528595.1
ENST00000375026.7
transmembrane protein 225
chr17_-_5234801 0.17 ENST00000571800.5
ENST00000574081.6
ENST00000399600.8
ENST00000574297.1
SLP adaptor and CSK interacting membrane protein
chr1_-_225428813 0.17 ENST00000338179.6
ENST00000425080.1
lamin B receptor
chr17_-_41620801 0.17 ENST00000648859.1
keratin 17
chr6_-_11807045 0.16 ENST00000379415.6
androgen dependent TFPI regulating protein
chr12_+_75480745 0.16 ENST00000266659.8
GLI pathogenesis related 1
chr14_-_24263162 0.16 ENST00000206765.11
ENST00000544573.5
transglutaminase 1
chr5_+_179820895 0.16 ENST00000504627.1
ENST00000389805.9
ENST00000510187.5
sequestosome 1
chr4_-_79408198 0.16 ENST00000358842.5
glycerol kinase 2
chr17_-_42181081 0.15 ENST00000607371.5
potassium voltage-gated channel subfamily H member 4
chr12_+_75480800 0.15 ENST00000456650.7
GLI pathogenesis related 1
chr20_-_653189 0.15 ENST00000381962.4
sulfiredoxin 1
chr6_+_47698538 0.15 ENST00000327753.7
adhesion G protein-coupled receptor F4
chr8_-_30727777 0.15 ENST00000537535.5
ENST00000541648.5
ENST00000546342.5
ENST00000221130.11
glutathione-disulfide reductase
chr16_+_57628684 0.15 ENST00000567397.5
ENST00000568979.5
ENST00000672974.1
adhesion G protein-coupled receptor G1
chr19_+_18588789 0.15 ENST00000450195.6
ENST00000358607.11
required for excision 1-B domain containing
chr1_+_84144260 0.15 ENST00000370685.7
protein kinase cAMP-activated catalytic subunit beta
chr6_+_47698574 0.15 ENST00000283303.3
adhesion G protein-coupled receptor F4
chr17_-_42181116 0.15 ENST00000264661.4
potassium voltage-gated channel subfamily H member 4
chr12_-_86838867 0.15 ENST00000621808.4
MGAT4 family member C
chr11_+_10456186 0.15 ENST00000528723.5
adenosine monophosphate deaminase 3
chr17_+_4950147 0.15 ENST00000522301.5
enolase 3
chr9_-_137188540 0.15 ENST00000323927.3
anaphase promoting complex subunit 2
chr2_-_186849164 0.15 ENST00000295131.3
zinc finger SWIM-type containing 2
chr22_+_22704265 0.14 ENST00000390307.2
immunoglobulin lambda variable 3-22
chr1_+_75786246 0.14 ENST00000319942.8
Rab geranylgeranyltransferase subunit beta
chr12_-_121016345 0.14 ENST00000535367.1
ENST00000538296.5
ENST00000288757.7
ENST00000539736.5
ENST00000537817.5
chromosome 12 open reading frame 43
chr12_-_14961610 0.14 ENST00000542276.1
Rho GDP dissociation inhibitor beta
chr1_+_152663378 0.14 ENST00000368784.2
late cornified envelope 2D
chr9_-_26947222 0.14 ENST00000520884.5
ENST00000397292.8
phospholipase A2 activating protein
chr11_+_119087979 0.14 ENST00000535253.5
ENST00000392841.1
ENST00000648374.1
hydroxymethylbilane synthase
chr2_+_234050732 0.14 ENST00000425558.1
secreted phosphoprotein 2
chr2_+_231056845 0.14 ENST00000677230.1
ENST00000677259.1
ENST00000677180.1
ENST00000409643.6
ENST00000619128.5
ENST00000678679.1
ENST00000676740.1
ENST00000308696.11
ENST00000440838.5
ENST00000373635.9
proteasome 26S subunit, non-ATPase 1
chr15_+_65045377 0.14 ENST00000334287.3
solute carrier family 51 subunit beta
chr6_+_44247866 0.13 ENST00000371554.2
heat shock protein 90 alpha family class B member 1
chr6_+_44247087 0.13 ENST00000353801.7
ENST00000371646.10
heat shock protein 90 alpha family class B member 1
chr1_+_160190567 0.13 ENST00000368078.8
calsequestrin 1
chr3_+_184299198 0.13 ENST00000417952.5
ENST00000310118.9
proteasome 26S subunit, non-ATPase 2
chr9_-_35072561 0.13 ENST00000678650.1
valosin containing protein
chr16_+_22297375 0.13 ENST00000615879.4
ENST00000299853.10
ENST00000564209.5
ENST00000565358.5
ENST00000418581.6
ENST00000564883.5
ENST00000359210.8
ENST00000563024.5
RNA polymerase III subunit E
chr1_+_152675295 0.13 ENST00000368783.1
late cornified envelope 2C
chr2_+_17878637 0.12 ENST00000304101.9
potassium voltage-gated channel modifier subfamily S member 3
chr17_+_2594148 0.12 ENST00000675331.1
platelet activating factor acetylhydrolase 1b regulatory subunit 1
chr17_+_2593925 0.12 ENST00000674717.1
ENST00000676353.1
ENST00000675202.1
ENST00000674608.1
ENST00000676098.1
platelet activating factor acetylhydrolase 1b regulatory subunit 1
chr12_-_14961256 0.12 ENST00000541380.5
Rho GDP dissociation inhibitor beta
chr7_-_116030750 0.12 ENST00000265440.12
ENST00000320239.11
transcription factor EC
chr2_-_219308963 0.12 ENST00000423636.6
ENST00000442029.5
ENST00000412847.5
protein tyrosine phosphatase receptor type N
chr5_-_150155828 0.12 ENST00000261799.9
platelet derived growth factor receptor beta
chr17_-_63827647 0.12 ENST00000584574.5
ENST00000585145.1
ENST00000427159.7
FtsJ RNA 2'-O-methyltransferase 3
chr14_-_106622837 0.12 ENST00000390628.3
immunoglobulin heavy variable 1-58
chr8_-_143939543 0.12 ENST00000345136.8
plectin
chr14_-_105987068 0.12 ENST00000390594.3
immunoglobulin heavy variable 1-2
chr15_+_41559189 0.12 ENST00000263798.8
TYRO3 protein tyrosine kinase
chr16_+_57628507 0.12 ENST00000456916.5
ENST00000567154.5
ENST00000388813.9
ENST00000562558.6
ENST00000566271.6
ENST00000563374.5
ENST00000673126.2
ENST00000562631.7
ENST00000568234.5
ENST00000565770.5
ENST00000566164.5
adhesion G protein-coupled receptor G1
chr16_+_78022538 0.11 ENST00000651443.1
ENST00000299642.10
C-type lectin domain family 3 member A
chr2_-_152098810 0.11 ENST00000636442.1
ENST00000638005.1
calcium voltage-gated channel auxiliary subunit beta 4
chr5_-_177496845 0.11 ENST00000506537.1
PDZ and LIM domain 7
chr1_-_46132650 0.11 ENST00000372006.5
ENST00000425892.2
ENST00000420542.5
phosphoinositide-3-kinase regulatory subunit 3
chrX_-_57680260 0.11 ENST00000434992.1
NLR family pyrin domain containing 2B
chr22_+_22395005 0.11 ENST00000390298.2
immunoglobulin lambda variable 7-43
chr18_-_57586668 0.11 ENST00000592699.6
ENST00000382873.8
ENST00000262093.11
ENST00000652755.1
ferrochelatase
chr17_-_60392333 0.11 ENST00000590133.5
ubiquitin specific peptidase 32
chr18_-_37485747 0.11 ENST00000589229.5
ENST00000587819.5
CUGBP Elav-like family member 4
chr10_+_69630227 0.11 ENST00000373279.6
family with sequence similarity 241 member B
chr5_+_161848112 0.11 ENST00000393943.10
gamma-aminobutyric acid type A receptor subunit alpha1
chr19_+_8832398 0.11 ENST00000595891.1
methyl-CpG binding domain protein 3 like 1
chr12_-_52949818 0.11 ENST00000546897.5
ENST00000552551.5
keratin 8
chr4_-_38856807 0.11 ENST00000506146.5
ENST00000436693.6
ENST00000508254.5
ENST00000514655.1
toll like receptor 1
toll like receptor 6
chr3_-_149576203 0.11 ENST00000472417.1
WW domain containing transcription regulator 1
chr1_-_161307420 0.10 ENST00000491222.5
ENST00000672287.2
myelin protein zero
chr2_+_171999937 0.10 ENST00000315796.5
methionyl aminopeptidase type 1D, mitochondrial
chr12_+_75334675 0.10 ENST00000312442.2
GLIPR1 like 1
chr11_-_2903490 0.10 ENST00000455942.3
ENST00000625099.4
solute carrier family 22 member 18 antisense
chr17_-_58531941 0.10 ENST00000581607.1
ENST00000317256.10
ENST00000426861.5
ENST00000580809.5
ENST00000577729.5
ENST00000583291.1
septin 4
chrX_-_153944621 0.10 ENST00000393700.8
renin binding protein
chr1_+_43337803 0.10 ENST00000372470.9
ENST00000413998.7
MPL proto-oncogene, thrombopoietin receptor
chr22_-_45212431 0.10 ENST00000496226.1
ENST00000251993.11
KIAA0930
chr9_-_127874964 0.10 ENST00000373156.5
adenylate kinase 1
chr12_+_75334655 0.10 ENST00000378695.9
GLIPR1 like 1
chr7_+_103347635 0.10 ENST00000679250.1
ENST00000292644.5
ENST00000425206.6
proteasome 26S subunit, ATPase 2
chrX_-_20141810 0.10 ENST00000379593.1
ENST00000379607.10
eukaryotic translation initiation factor 1A X-linked
chr22_+_22720615 0.10 ENST00000390309.2
immunoglobulin lambda variable 3-19
chr14_+_21918161 0.10 ENST00000390439.2
T cell receptor alpha variable 13-2
chr8_-_93741001 0.10 ENST00000518597.2
ENST00000520560.6
ENST00000399300.7
RNA binding motif protein 12B
chr12_-_55707865 0.10 ENST00000347027.10
ENST00000257879.11
ENST00000553804.6
integrin subunit alpha 7
chr8_-_93740975 0.10 ENST00000517700.6
RNA binding motif protein 12B
chrX_+_150363306 0.10 ENST00000370401.7
ENST00000432680.7
mastermind like domain containing 1
chr5_-_177496802 0.10 ENST00000506161.5
PDZ and LIM domain 7
chr6_-_32407123 0.09 ENST00000374993.4
ENST00000544175.2
ENST00000454136.7
ENST00000446536.2
butyrophilin like 2
chr12_+_50400809 0.09 ENST00000293618.12
ENST00000429001.7
ENST00000398473.7
ENST00000548174.5
ENST00000548697.5
ENST00000548993.5
ENST00000614335.4
ENST00000522085.5
ENST00000615080.4
ENST00000518444.5
ENST00000551886.5
ENST00000523389.5
ENST00000518561.5
ENST00000347328.9
ENST00000550260.1
La ribonucleoprotein 4
chr9_+_35538619 0.09 ENST00000455600.1
RUN and SH3 domain containing 2
chr12_-_57632668 0.09 ENST00000552350.5
ENST00000548888.5
beta-1,4-N-acetyl-galactosaminyltransferase 1
chrX_+_150363258 0.09 ENST00000683696.1
mastermind like domain containing 1
chr19_-_45639104 0.09 ENST00000586770.5
ENST00000591721.5
ENST00000245925.8
ENST00000590043.5
ENST00000589876.5
EMAP like 2
chr19_-_6670117 0.09 ENST00000245912.7
TNF superfamily member 14
chr7_-_100428657 0.09 ENST00000360951.8
ENST00000398027.6
ENST00000684423.1
ENST00000472716.1
zinc finger CW-type and PWWP domain containing 1
chr1_-_158686700 0.09 ENST00000643759.2
spectrin alpha, erythrocytic 1
chr19_-_6670151 0.09 ENST00000675206.1
TNF superfamily member 14
chr22_-_19479160 0.09 ENST00000399523.5
ENST00000421968.6
ENST00000263202.15
ENST00000447868.5
ubiquitin recognition factor in ER associated degradation 1
chr7_-_19773569 0.09 ENST00000422233.5
ENST00000433641.5
ENST00000405844.6
transmembrane protein 196
chr1_-_150235943 0.09 ENST00000533654.5
acidic nuclear phosphoprotein 32 family member E
chr2_-_61537740 0.09 ENST00000678081.1
ENST00000676889.1
ENST00000677850.1
ENST00000676789.1
exportin 1
chr15_+_59611776 0.09 ENST00000396065.3
ENST00000560585.5
glucosaminyl (N-acetyl) transferase 3, mucin type
chr17_-_67366562 0.09 ENST00000356126.8
ENST00000357146.4
proteasome 26S subunit, non-ATPase 12
chrX_-_71106728 0.09 ENST00000374251.6
chromosome X open reading frame 65
chr17_-_15263162 0.09 ENST00000674673.1
ENST00000675950.1
peripheral myelin protein 22
chr8_-_93740718 0.09 ENST00000519109.6
RNA binding motif protein 12B
chr3_+_69866217 0.09 ENST00000314589.10
melanocyte inducing transcription factor
chr20_+_10218808 0.09 ENST00000254976.7
ENST00000304886.6
synaptosome associated protein 25
chr22_+_29306582 0.09 ENST00000616432.4
ENST00000416823.1
ENST00000428622.1
growth arrest specific 2 like 1
chr10_+_84139491 0.08 ENST00000372134.6
growth hormone inducible transmembrane protein
chr12_-_56636318 0.08 ENST00000549506.5
ENST00000379441.7
ENST00000551812.5
bromodomain adjacent to zinc finger domain 2A

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) regulation of chromatin silencing at telomere(GO:0031938) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.3 1.0 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.1 0.6 GO:0042377 menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
0.1 0.4 GO:1901899 positive regulation of relaxation of cardiac muscle(GO:1901899)
0.1 0.4 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1 0.3 GO:1901388 regulation of transforming growth factor beta activation(GO:1901388) negative regulation of transforming growth factor beta activation(GO:1901389)
0.1 0.2 GO:0090176 microtubule cytoskeleton organization involved in establishment of planar polarity(GO:0090176)
0.1 0.5 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 0.3 GO:1904387 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.1 0.2 GO:0060931 sinoatrial node cell development(GO:0060931)
0.1 0.7 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887)
0.1 0.3 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.9 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.3 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.3 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.4 GO:0006741 NADP biosynthetic process(GO:0006741) regulation of NADP metabolic process(GO:1902031)
0.0 0.1 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.0 0.2 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.2 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.1 GO:1903004 flavin adenine dinucleotide metabolic process(GO:0072387) regulation of protein K63-linked deubiquitination(GO:1903004) positive regulation of protein K63-linked deubiquitination(GO:1903006)
0.0 0.0 GO:0038183 bile acid signaling pathway(GO:0038183)
0.0 0.1 GO:1904692 positive regulation of type B pancreatic cell proliferation(GO:1904692)
0.0 0.1 GO:0072277 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.0 0.1 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.9 GO:0042226 interleukin-6 biosynthetic process(GO:0042226)
0.0 0.4 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.3 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0 0.6 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.2 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.2 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.0 0.2 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.1 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.0 0.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.1 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.1 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.1 GO:0099557 trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission(GO:0099557)
0.0 0.1 GO:0097338 response to clozapine(GO:0097338)
0.0 0.1 GO:0001983 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0 0.2 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.1 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.1 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.6 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.6 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.2 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.6 GO:0071305 cellular response to vitamin D(GO:0071305)
0.0 0.1 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.1 GO:0006051 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.0 0.2 GO:0034036 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.0 0.3 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.0 GO:0098759 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.0 1.4 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.0 0.1 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.0 GO:0035732 nitric oxide storage(GO:0035732)
0.0 0.1 GO:0060356 leucine import(GO:0060356)
0.0 0.1 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.1 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.2 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.2 GO:0061635 negative regulation of growth of symbiont in host(GO:0044130) regulation of protein complex stability(GO:0061635)
0.0 0.7 GO:0043486 histone exchange(GO:0043486)
0.0 0.4 GO:0015695 organic cation transport(GO:0015695)
0.0 0.1 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.2 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.0 0.1 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.4 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.5 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.0 0.1 GO:0060050 positive regulation of protein glycosylation(GO:0060050)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.1 0.5 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 0.3 GO:0034515 proteasome storage granule(GO:0034515)
0.1 0.3 GO:1990913 sperm head plasma membrane(GO:1990913) ooplasm(GO:1990917)
0.1 0.4 GO:0097513 myosin II filament(GO:0097513)
0.1 0.3 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.1 0.7 GO:0098845 postsynaptic endosome(GO:0098845)
0.1 0.7 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.2 GO:0044753 amphisome(GO:0044753)
0.0 0.5 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.2 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.9 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 0.6 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.3 GO:0097451 glial limiting end-foot(GO:0097451)
0.0 0.1 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.4 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.3 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 0.1 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.9 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.1 GO:0005873 plus-end kinesin complex(GO:0005873)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.0 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.0 0.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.1 0.5 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.4 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.1 1.4 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.1 0.3 GO:0002135 CTP binding(GO:0002135)
0.1 0.3 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.1 0.4 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 0.7 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.2 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.0 0.1 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.0 0.1 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.4 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.5 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.1 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.0 0.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.5 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.3 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.3 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.3 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.1 GO:0031626 beta-endorphin binding(GO:0031626)
0.0 0.3 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.8 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.2 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.0 0.1 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.0 0.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.4 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.1 GO:0042835 BRE binding(GO:0042835)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.0 GO:0019959 interleukin-8 binding(GO:0019959)
0.0 0.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.5 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 3.8 GO:0008168 methyltransferase activity(GO:0008168)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.2 GO:0050542 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0 0.1 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.6 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 4.3 GO:0008017 microtubule binding(GO:0008017)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.5 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.6 PID AURORA A PATHWAY Aurora A signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 1.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.5 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 1.1 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.9 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.4 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.2 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.4 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.5 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.3 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane