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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for BACH2

Z-value: 0.55

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Transcription factors associated with BACH2

Gene Symbol Gene ID Gene Info
ENSG00000112182.15 BACH2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BACH2hg38_v1_chr6_-_90296908_90296922,
hg38_v1_chr6_-_90296824_90296851
-0.365.2e-02Click!

Activity profile of BACH2 motif

Sorted Z-values of BACH2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of BACH2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_+_150508074 3.70 ENST00000369049.8
extracellular matrix protein 1
chr1_+_150508099 3.69 ENST00000346569.6
ENST00000369047.9
extracellular matrix protein 1
chr18_+_23873000 2.59 ENST00000269217.11
ENST00000587184.5
laminin subunit alpha 3
chr2_+_113117889 2.04 ENST00000361779.7
ENST00000259206.9
ENST00000354115.6
interleukin 1 receptor antagonist
chr17_-_41612757 2.02 ENST00000301653.9
ENST00000593067.1
keratin 16
chr11_-_102798148 1.90 ENST00000315274.7
matrix metallopeptidase 1
chr20_+_46008900 1.78 ENST00000372330.3
matrix metallopeptidase 9
chr6_+_73695779 1.77 ENST00000422508.6
ENST00000437994.6
CD109 molecule
chr12_-_119804472 1.73 ENST00000678087.1
ENST00000677993.1
citron rho-interacting serine/threonine kinase
chr6_+_73696145 1.73 ENST00000287097.6
CD109 molecule
chr12_-_119804298 1.72 ENST00000678652.1
ENST00000678494.1
citron rho-interacting serine/threonine kinase
chr12_+_53098846 1.63 ENST00000650247.1
ENST00000549628.1
insulin like growth factor binding protein 6
chr19_-_35528221 1.62 ENST00000588674.5
ENST00000452271.7
ENST00000518157.1
suprabasin
chr1_+_152908538 1.54 ENST00000368764.4
involucrin
chr7_+_48088596 1.46 ENST00000416681.5
ENST00000331803.8
ENST00000432131.5
uridine phosphorylase 1
chr3_-_48595267 1.45 ENST00000328333.12
ENST00000681320.1
collagen type VII alpha 1 chain
chr1_-_153549120 1.39 ENST00000368712.1
S100 calcium binding protein A3
chr1_-_204151884 1.20 ENST00000367201.7
ethanolamine kinase 2
chr11_-_62556230 1.15 ENST00000530285.5
AHNAK nucleoprotein
chr1_-_204152010 1.13 ENST00000367202.9
ethanolamine kinase 2
chr1_-_153549238 1.06 ENST00000368713.8
S100 calcium binding protein A3
chr11_-_65900375 0.98 ENST00000312562.7
FOS like 1, AP-1 transcription factor subunit
chr4_+_73740541 0.97 ENST00000401931.1
ENST00000307407.8
C-X-C motif chemokine ligand 8
chr1_+_153031195 0.97 ENST00000307098.5
small proline rich protein 1B
chr11_-_102955705 0.96 ENST00000615555.4
ENST00000340273.4
ENST00000260302.8
matrix metallopeptidase 13
chr11_-_6320494 0.88 ENST00000303927.4
ENST00000530979.1
caveolae associated protein 3
chr11_-_65900413 0.84 ENST00000448083.6
ENST00000531493.5
ENST00000532401.1
FOS like 1, AP-1 transcription factor subunit
chr7_-_23347704 0.82 ENST00000619562.4
insulin like growth factor 2 mRNA binding protein 3
chr12_-_94616061 0.82 ENST00000551457.1
transmembrane and coiled-coil domain family 3
chr18_+_63775395 0.81 ENST00000398019.7
serpin family B member 7
chr18_+_63775369 0.80 ENST00000540675.5
serpin family B member 7
chr19_-_38773432 0.78 ENST00000599035.1
ENST00000378626.5
galectin 7
chr17_-_78925376 0.77 ENST00000262768.11
TIMP metallopeptidase inhibitor 2
chr1_+_154405326 0.72 ENST00000368485.8
interleukin 6 receptor
chr17_+_75721327 0.70 ENST00000579662.5
integrin subunit beta 4
chr19_+_38789198 0.70 ENST00000314980.5
galectin 7B
chr6_+_41637005 0.69 ENST00000419164.6
ENST00000373051.6
MyoD family inhibitor
chr6_-_43629222 0.66 ENST00000307126.10
GTP binding protein 2
chr20_-_1329131 0.65 ENST00000360779.4
syndecan binding protein 2
chr16_+_58500047 0.64 ENST00000566192.5
ENST00000565088.5
ENST00000568640.5
NDRG family member 4
chr5_-_177496845 0.64 ENST00000506537.1
PDZ and LIM domain 7
chr9_-_107489754 0.64 ENST00000610832.1
ENST00000374672.5
Kruppel like factor 4
chr1_+_154405193 0.62 ENST00000622330.4
ENST00000344086.8
interleukin 6 receptor
chr1_-_6491664 0.62 ENST00000377728.8
ENST00000675093.1
pleckstrin homology and RhoGEF domain containing G5
chr17_+_75721471 0.61 ENST00000450894.7
integrin subunit beta 4
chr3_-_98522514 0.61 ENST00000503004.5
ENST00000506575.1
ENST00000513452.5
ENST00000515620.5
claudin domain containing 1
chr7_+_143381286 0.61 ENST00000449630.5
ENST00000322764.10
ENST00000457235.5
zyxin
chr5_-_177496802 0.60 ENST00000506161.5
PDZ and LIM domain 7
chr1_+_26280117 0.58 ENST00000319041.6
SH3 domain binding glutamate rich protein like 3
chr16_+_58500135 0.57 ENST00000563978.5
ENST00000569923.5
ENST00000356752.8
ENST00000563799.5
ENST00000562999.5
ENST00000570248.5
ENST00000562731.5
ENST00000568424.1
NDRG family member 4
chr9_-_35112379 0.55 ENST00000488109.6
family with sequence similarity 214 member B
chr11_-_47185840 0.55 ENST00000539589.5
ENST00000528462.5
protein kinase C and casein kinase substrate in neurons 3
chr11_-_66336396 0.53 ENST00000627248.1
ENST00000311320.9
Ras and Rab interactor 1
chr6_+_63571702 0.52 ENST00000672924.1
protein tyrosine phosphatase 4A1
chr19_-_51020154 0.51 ENST00000391805.5
ENST00000599077.1
kallikrein related peptidase 10
chr6_-_35921079 0.51 ENST00000507909.1
ENST00000373825.7
SRSF protein kinase 1
chr6_-_35921128 0.51 ENST00000510290.5
ENST00000423325.6
SRSF protein kinase 1
chr19_-_51034993 0.49 ENST00000684732.1
kallikrein related peptidase 12
chr15_+_88638947 0.48 ENST00000559876.2
interferon stimulated exonuclease gene 20
chr19_-_35513641 0.47 ENST00000339686.8
ENST00000447113.6
dermokine
chr5_+_150497772 0.46 ENST00000523767.5
N-deacetylase and N-sulfotransferase 1
chr8_-_30658176 0.46 ENST00000355904.9
general transcription factor IIE subunit 2
chr1_-_156705575 0.43 ENST00000368222.8
cellular retinoic acid binding protein 2
chr5_-_88731827 0.43 ENST00000627170.2
myocyte enhancer factor 2C
chr3_+_191329020 0.42 ENST00000392456.4
coiled-coil domain containing 50
chr7_+_134843884 0.42 ENST00000445569.6
caldesmon 1
chr19_-_51034840 0.42 ENST00000529888.5
kallikrein related peptidase 12
chr10_+_17228215 0.42 ENST00000544301.7
vimentin
chr15_+_59611776 0.41 ENST00000396065.3
ENST00000560585.5
glucosaminyl (N-acetyl) transferase 3, mucin type
chr19_-_51034892 0.40 ENST00000319590.8
ENST00000250351.4
kallikrein related peptidase 12
chr19_-_51020019 0.40 ENST00000309958.7
kallikrein related peptidase 10
chr6_+_32153441 0.40 ENST00000414204.5
ENST00000361568.6
ENST00000395523.5
palmitoyl-protein thioesterase 2
chr19_-_40257045 0.39 ENST00000578615.6
AKT serine/threonine kinase 2
chr1_-_151992571 0.39 ENST00000368809.1
S100 calcium binding protein A10
chr1_-_39691450 0.38 ENST00000612703.3
ENST00000617690.2
hippocalcin like 4
chr1_-_39691393 0.38 ENST00000372844.8
hippocalcin like 4
chr5_-_176416222 0.38 ENST00000508425.5
clathrin light chain B
chr17_-_45425620 0.37 ENST00000376922.6
Rho GTPase activating protein 27
chr15_+_88639009 0.37 ENST00000306072.10
interferon stimulated exonuclease gene 20
chr5_-_88785493 0.37 ENST00000503554.4
myocyte enhancer factor 2C
chr3_-_151316795 0.37 ENST00000260843.5
G protein-coupled receptor 87
chr18_+_63476927 0.36 ENST00000489441.5
ENST00000382771.9
ENST00000424602.1
serpin family B member 5
chr1_+_36155930 0.35 ENST00000316156.8
MAP7 domain containing 1
chr19_+_44644025 0.35 ENST00000406449.8
PVR cell adhesion molecule
chr1_-_6602885 0.35 ENST00000377663.3
kelch like family member 21
chr1_+_156126160 0.35 ENST00000448611.6
ENST00000368297.5
lamin A/C
chr1_-_6602859 0.34 ENST00000377658.8
kelch like family member 21
chr1_+_36156096 0.34 ENST00000474796.2
ENST00000373150.8
ENST00000373151.6
MAP7 domain containing 1
chr11_-_2903490 0.33 ENST00000455942.3
ENST00000625099.4
solute carrier family 22 member 18 antisense
chr9_+_4985227 0.33 ENST00000381652.4
Janus kinase 2
chr5_-_176416523 0.32 ENST00000502877.1
ENST00000310418.9
ENST00000345807.7
clathrin light chain B
chr7_+_1530684 0.31 ENST00000343242.9
MAF bZIP transcription factor K
chr2_-_65366650 0.31 ENST00000443619.6
sprouty related EVH1 domain containing 2
chr5_+_179820895 0.30 ENST00000504627.1
ENST00000389805.9
ENST00000510187.5
sequestosome 1
chr1_-_158686700 0.29 ENST00000643759.2
spectrin alpha, erythrocytic 1
chr14_-_75176593 0.28 ENST00000303575.9
transmembrane p24 trafficking protein 10
chr5_-_141682192 0.28 ENST00000508305.5
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr18_+_58671439 0.28 ENST00000649217.2
MALT1 paracaspase
chr9_+_100429511 0.28 ENST00000613183.1
Myb/SANT DNA binding domain containing 3
chr17_-_29176752 0.28 ENST00000533112.5
myosin XVIIIA
chr8_-_67746348 0.28 ENST00000297770.10
carboxypeptidase A6
chr2_+_169069537 0.28 ENST00000428522.5
ENST00000450153.1
ENST00000674881.1
ENST00000421653.5
dehydrogenase/reductase 9
chr11_-_64246190 0.28 ENST00000392210.6
protein phosphatase 1 regulatory inhibitor subunit 14B
chr5_+_141637398 0.26 ENST00000518856.1
RELT like 2
chr5_-_141682211 0.26 ENST00000239440.9
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr1_+_19312341 0.26 ENST00000400548.6
solute carrier family 66 member 1
chr16_-_72620 0.26 ENST00000262316.10
rhomboid 5 homolog 1
chr17_-_28718405 0.26 ENST00000430132.6
ENST00000301043.10
ENST00000412625.5
RAB34, member RAS oncogene family
chr20_+_45406560 0.25 ENST00000372717.5
ENST00000360981.8
dysbindin domain containing 2
chr12_-_47758828 0.25 ENST00000389212.7
ENST00000449771.7
Rap guanine nucleotide exchange factor 3
chr22_+_22720615 0.25 ENST00000390309.2
immunoglobulin lambda variable 3-19
chr17_+_4950147 0.24 ENST00000522301.5
enolase 3
chr21_+_29299368 0.24 ENST00000399921.5
BTB domain and CNC homolog 1
chr1_+_19312296 0.24 ENST00000375155.7
ENST00000375153.8
solute carrier family 66 member 1
chr3_+_11137093 0.24 ENST00000438284.2
histamine receptor H1
chr21_+_29298890 0.23 ENST00000286800.8
BTB domain and CNC homolog 1
chr8_-_58659534 0.23 ENST00000427130.6
neutral sphingomyelinase activation associated factor
chrX_-_15493234 0.22 ENST00000380420.10
pirin
chr11_+_64924673 0.22 ENST00000164133.7
ENST00000532850.1
protein phosphatase 2 regulatory subunit B'beta
chr4_-_993430 0.21 ENST00000361661.6
ENST00000622731.4
solute carrier family 26 member 1
chr11_-_2929412 0.21 ENST00000314222.5
pleckstrin homology like domain family A member 2
chr4_-_79408198 0.21 ENST00000358842.5
glycerol kinase 2
chr16_-_2858154 0.21 ENST00000571228.1
ENST00000161006.8
serine protease 22
chr6_-_83431038 0.21 ENST00000369705.4
malic enzyme 1
chr11_+_73289403 0.21 ENST00000535931.2
ENST00000544437.6
pyrimidinergic receptor P2Y6
chr1_-_94541636 0.20 ENST00000370207.4
coagulation factor III, tissue factor
chr9_-_124415421 0.20 ENST00000259457.8
ENST00000441097.1
proteasome 20S subunit beta 7
chr3_+_19947316 0.20 ENST00000422242.1
RAB5A, member RAS oncogene family
chrX_-_130110479 0.20 ENST00000308167.10
E74 like ETS transcription factor 4
chr1_-_94541746 0.19 ENST00000334047.12
coagulation factor III, tissue factor
chr9_-_127578989 0.19 ENST00000373314.7
niban apoptosis regulator 2
chr17_-_75154534 0.19 ENST00000356033.8
Jupiter microtubule associated homolog 1
chr17_+_82217929 0.19 ENST00000580098.6
solute carrier family 16 member 3
chr16_+_67537439 0.19 ENST00000428437.6
ENST00000569253.5
RHO family interacting cell polarization regulator 1
chr22_+_20507571 0.19 ENST00000414658.5
ENST00000432052.5
ENST00000292733.11
ENST00000263205.11
ENST00000406969.5
mediator complex subunit 15
chr12_+_56338873 0.19 ENST00000228534.6
interleukin 23 subunit alpha
chr4_+_70195719 0.19 ENST00000683306.1
odontogenic, ameloblast associated
chrX_-_130110679 0.18 ENST00000335997.11
E74 like ETS transcription factor 4
chr1_+_36088868 0.18 ENST00000373178.5
ADP-ribosylserine hydrolase
chr14_+_69260146 0.18 ENST00000448469.8
polypeptide N-acetylgalactosaminyltransferase 16
chr10_+_84328625 0.18 ENST00000224756.12
coiled-coil serine rich protein 2
chr11_+_35618450 0.18 ENST00000317811.6
four-jointed box kinase 1
chr17_-_28717792 0.17 ENST00000636772.1
RAB34, member RAS oncogene family
chr12_-_38905584 0.17 ENST00000331366.10
copine 8
chr20_+_45406162 0.17 ENST00000357275.6
ENST00000372720.7
dysbindin domain containing 2
chr1_+_966466 0.17 ENST00000379410.8
ENST00000379407.7
ENST00000379409.6
pleckstrin homology domain containing N1
chr17_-_28717860 0.16 ENST00000395245.9
RAB34, member RAS oncogene family
chr22_+_22030934 0.16 ENST00000390282.2
immunoglobulin lambda variable 4-69
chrX_-_16712865 0.16 ENST00000380241.7
CTP synthase 2
chr17_+_77319465 0.16 ENST00000329047.13
septin 9
chrX_-_155264471 0.16 ENST00000369454.4
RAB39B, member RAS oncogene family
chr3_-_132037800 0.15 ENST00000617767.4
copine 4
chr10_-_24706622 0.15 ENST00000680286.1
Rho GTPase activating protein 21
chr17_-_28718147 0.15 ENST00000436730.7
ENST00000625712.2
ENST00000450529.5
ENST00000583538.5
ENST00000419712.7
ENST00000580843.6
ENST00000582934.1
ENST00000415040.6
ENST00000353676.9
ENST00000453384.7
RAB34, member RAS oncogene family
chr17_-_49210567 0.15 ENST00000507680.6
G protein subunit gamma transducin 2
chr15_+_44537085 0.15 ENST00000424492.7
eukaryotic translation initiation factor 3 subunit J
chr3_+_121593363 0.15 ENST00000338040.6
F-box protein 40
chr16_+_74296789 0.14 ENST00000219313.9
ENST00000567958.5
ENST00000568615.2
proteasome 26S subunit, non-ATPase 7
chr1_+_156893678 0.14 ENST00000292357.8
ENST00000338302.7
ENST00000455314.5
platelet endothelial aggregation receptor 1
chr10_+_84328581 0.14 ENST00000359979.8
ENST00000372088.8
coiled-coil serine rich protein 2
chr17_-_35063648 0.14 ENST00000394597.7
ring finger and FYVE like domain containing E3 ubiquitin protein ligase
chr19_+_13731744 0.13 ENST00000586600.5
coiled-coil domain containing 130
chr8_-_58659742 0.13 ENST00000038176.8
neutral sphingomyelinase activation associated factor
chr5_+_160009113 0.13 ENST00000522793.5
ENST00000682719.1
ENST00000684137.1
ENST00000683219.1
ENST00000684018.1
ENST00000231238.10
ENST00000682131.1
tetratricopeptide repeat domain 1
chr1_+_161524539 0.13 ENST00000309758.6
heat shock protein family A (Hsp70) member 6
chr8_+_24913752 0.13 ENST00000518131.5
ENST00000221166.10
ENST00000437366.2
neurofilament medium
chr17_-_50707855 0.13 ENST00000285243.7
ankyrin repeat domain 40
chr1_-_27490130 0.13 ENST00000618852.5
WASP family member 2
chr8_+_22987400 0.12 ENST00000519685.5
Rho related BTB domain containing 2
chr11_+_64359142 0.12 ENST00000528057.5
ENST00000334205.9
ribosomal protein S6 kinase A4
chr17_+_81683963 0.12 ENST00000676462.1
ENST00000679336.1
ENST00000678196.1
ENST00000677243.1
ENST00000677044.1
ENST00000677109.1
ENST00000677484.1
ENST00000678105.1
ENST00000677209.1
ENST00000329138.9
ENST00000677225.1
ENST00000678866.1
ENST00000676729.1
ENST00000572392.2
ENST00000577012.1
hepatocyte growth factor-regulated tyrosine kinase substrate
chr18_+_44700796 0.12 ENST00000677130.1
SET binding protein 1
chrX_+_41334154 0.12 ENST00000441189.4
ENST00000644513.1
ENST00000644109.1
ENST00000646122.1
ENST00000644074.1
ENST00000644876.2
ENST00000399959.7
ENST00000646319.1
DEAD-box helicase 3 X-linked
chr18_+_34710249 0.12 ENST00000680346.1
ENST00000348997.9
ENST00000681274.1
ENST00000680822.1
ENST00000680767.2
ENST00000597599.5
ENST00000444659.6
dystrobrevin alpha
chr10_+_102395693 0.12 ENST00000652277.1
ENST00000189444.11
ENST00000661543.1
nuclear factor kappa B subunit 2
chr3_-_98522869 0.12 ENST00000502288.5
ENST00000512147.5
ENST00000341181.11
ENST00000510541.5
ENST00000503621.5
ENST00000511081.5
ENST00000507874.5
ENST00000502299.5
ENST00000508659.5
ENST00000510545.5
ENST00000511667.5
ENST00000394185.6
claudin domain containing 1
chr16_-_75267988 0.12 ENST00000393422.6
BCAR1 scaffold protein, Cas family member
chrX_-_49043345 0.12 ENST00000315869.8
transcription factor binding to IGHM enhancer 3
chr20_+_44401269 0.11 ENST00000443598.6
ENST00000415691.2
hepatocyte nuclear factor 4 alpha
chr2_+_231056845 0.11 ENST00000677230.1
ENST00000677259.1
ENST00000677180.1
ENST00000409643.6
ENST00000619128.5
ENST00000678679.1
ENST00000676740.1
ENST00000308696.11
ENST00000440838.5
ENST00000373635.9
proteasome 26S subunit, non-ATPase 1
chr10_-_71851239 0.11 ENST00000394936.8
prosaposin
chr1_+_12063285 0.11 ENST00000263932.7
TNF receptor superfamily member 8
chr1_-_12616762 0.11 ENST00000464917.5
dehydrogenase/reductase 3
chr3_+_57060658 0.11 ENST00000334325.2
spermatogenesis associated 12
chr17_+_27471999 0.10 ENST00000583370.5
ENST00000509603.6
ENST00000268763.10
ENST00000398988.7
kinase suppressor of ras 1
chr1_+_12063357 0.10 ENST00000417814.3
TNF receptor superfamily member 8
chr4_-_993376 0.10 ENST00000398520.6
ENST00000398516.3
solute carrier family 26 member 1
chr11_-_64245816 0.10 ENST00000542235.1
protein phosphatase 1 regulatory inhibitor subunit 14B
chr22_+_22322452 0.09 ENST00000390290.3
immunoglobulin lambda variable 1-51
chr16_+_57628507 0.09 ENST00000456916.5
ENST00000567154.5
ENST00000388813.9
ENST00000562558.6
ENST00000566271.6
ENST00000563374.5
ENST00000673126.2
ENST00000562631.7
ENST00000568234.5
ENST00000565770.5
ENST00000566164.5
adhesion G protein-coupled receptor G1
chr19_-_4065732 0.09 ENST00000601588.1
zinc finger and BTB domain containing 7A
chr19_+_43612083 0.09 ENST00000417606.3
serine/arginine repetitive matrix 5
chr11_+_102112445 0.08 ENST00000524575.5
Yes1 associated transcriptional regulator
chr15_-_25865076 0.08 ENST00000619904.1
ATPase phospholipid transporting 10A (putative)
chr3_+_184299198 0.08 ENST00000417952.5
ENST00000310118.9
proteasome 26S subunit, non-ATPase 2
chr1_-_51878799 0.08 ENST00000354831.11
ENST00000544028.5
nardilysin convertase
chr2_+_201116143 0.08 ENST00000443227.5
ENST00000309955.8
ENST00000341222.10
ENST00000341582.10
CASP8 and FADD like apoptosis regulator
chr20_+_44401397 0.08 ENST00000682427.1
ENST00000681977.1
ENST00000684136.1
ENST00000684046.1
ENST00000684476.1
ENST00000619550.5
ENST00000682169.1
hepatocyte nuclear factor 4 alpha
chr15_+_44537136 0.07 ENST00000261868.10
ENST00000535391.5
eukaryotic translation initiation factor 3 subunit J
chr17_-_67366562 0.07 ENST00000356126.8
ENST00000357146.4
proteasome 26S subunit, non-ATPase 12

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.5 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.5 1.5 GO:0046108 uridine metabolic process(GO:0046108)
0.4 1.5 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.3 1.4 GO:0002384 hepatic immune response(GO:0002384)
0.3 1.6 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.3 1.8 GO:0007296 vitellogenesis(GO:0007296)
0.3 0.9 GO:0043465 fermentation(GO:0006113) regulation of fermentation(GO:0043465)
0.3 2.0 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.2 7.4 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.2 1.8 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.2 0.6 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.2 0.8 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.2 0.5 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 3.9 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.4 GO:1990009 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473) retinal cell apoptotic process(GO:1990009)
0.1 0.8 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.1 0.2 GO:0030807 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.1 0.5 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.3 GO:1902724 mineralocorticoid receptor signaling pathway(GO:0031959) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.1 2.0 GO:0051546 keratinocyte migration(GO:0051546)
0.1 0.4 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.1 0.8 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.3 GO:1903028 positive regulation of opsonization(GO:1903028)
0.1 2.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 1.0 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.1 1.0 GO:0035092 sperm chromatin condensation(GO:0035092)
0.1 0.2 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.1 0.3 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 0.2 GO:0045556 TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556)
0.1 0.5 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 1.2 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.1 0.5 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.2 GO:0032962 regulation of inositol trisphosphate biosynthetic process(GO:0032960) positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.1 0.3 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.1 0.5 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.6 GO:0001866 NK T cell proliferation(GO:0001866)
0.1 3.5 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.7 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.3 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.0 1.0 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 0.2 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 1.6 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.2 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.0 0.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.2 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.7 GO:0002138 retinoic acid biosynthetic process(GO:0002138)
0.0 1.8 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 0.7 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.4 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.1 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.0 0.3 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.0 0.2 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.2 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.0 0.1 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.0 0.6 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.4 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.4 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.1 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.6 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.2 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 0.2 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.1 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.0 0.2 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:0042946 glucoside transport(GO:0042946)
0.0 0.3 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 1.1 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 1.1 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 1.0 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.3 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.4 GO:0002385 mucosal immune response(GO:0002385)
0.0 0.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.2 GO:0051683 establishment of Golgi localization(GO:0051683)
0.0 0.8 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.7 GO:0044380 protein localization to cytoskeleton(GO:0044380)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.6 GO:0005610 laminin-5 complex(GO:0005610)
0.4 7.4 GO:0031089 platelet dense granule lumen(GO:0031089)
0.3 1.4 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.2 1.4 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 1.6 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 0.3 GO:0044753 amphisome(GO:0044753)
0.1 0.7 GO:0005827 polar microtubule(GO:0005827)
0.1 3.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.2 GO:0034515 proteasome storage granule(GO:0034515)
0.1 0.3 GO:0032449 CBM complex(GO:0032449)
0.0 1.0 GO:0030056 hemidesmosome(GO:0030056)
0.0 2.5 GO:0001533 cornified envelope(GO:0001533)
0.0 0.3 GO:0032437 cuticular plate(GO:0032437)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.7 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.3 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.2 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 3.8 GO:0031985 Golgi cisterna(GO:0031985)
0.0 2.2 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 1.2 GO:0043034 costamere(GO:0043034)
0.0 0.6 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.2 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 0.1 GO:0097451 glial limiting end-foot(GO:0097451)
0.0 1.9 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.1 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 1.6 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.4 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 1.7 GO:0005882 intermediate filament(GO:0005882)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 7.4 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.7 2.0 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.5 1.5 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.4 1.3 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.3 2.3 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.3 0.8 GO:0008859 exoribonuclease II activity(GO:0008859)
0.1 2.9 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.1 0.4 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 0.6 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 0.5 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 3.5 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 0.3 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.4 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 0.4 GO:1990254 keratin filament binding(GO:1990254)
0.1 1.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.3 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.7 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.3 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.2 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.8 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.2 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.2 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 1.1 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.4 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 3.0 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.5 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 4.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 3.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.7 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.3 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.4 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0042947 glucoside transmembrane transporter activity(GO:0042947)
0.0 0.8 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 1.0 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.4 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.8 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 7.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 1.7 ST STAT3 PATHWAY STAT3 Pathway
0.0 2.7 PID RHOA PATHWAY RhoA signaling pathway
0.0 2.2 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.9 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 7.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.7 PID ARF 3PATHWAY Arf1 pathway
0.0 1.4 NABA COLLAGENS Genes encoding collagen proteins
0.0 7.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.4 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.1 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.5 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 2.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 3.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.7 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 1.5 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 2.2 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.7 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.6 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 3.8 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 1.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.8 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors