Project
Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)
Navigation
Downloads
Results for BATF
Z-value: 2.20
Motif logo
Transcription factors associated with BATF
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| BATF | hg38_v1_chr14_+_75522427_75522483 | -0.49 | 6.1e-03 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of BATF
| Promoter | Score | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr1_-_153460644 Show fit | 14.27 |
ENST00000368723.4
|
S100 calcium binding protein A7 |
|
| chr1_+_150508099 Show fit | 14.23 |
ENST00000346569.6
ENST00000369047.9 |
extracellular matrix protein 1 |
|
| chr19_-_50983815 Show fit | 14.08 |
ENST00000391807.5
ENST00000593904.1 ENST00000595820.6 |
kallikrein related peptidase 7 |
|
| chr9_+_33795551 Show fit | 12.70 |
ENST00000379405.4
|
serine protease 3 |
|
| chr18_+_23873000 Show fit | 12.29 |
ENST00000269217.11
ENST00000587184.5 |
laminin subunit alpha 3 |
|
| chr19_-_51001138 Show fit | 11.80 |
ENST00000593490.1
|
kallikrein related peptidase 8 |
|
| chr1_-_153549120 Show fit | 11.10 |
ENST00000368712.1
|
S100 calcium binding protein A3 |
|
| chr1_+_150508074 Show fit | 10.37 |
ENST00000369049.8
|
extracellular matrix protein 1 |
|
| chr1_-_153057504 Show fit | 9.67 |
ENST00000392653.3
|
small proline rich protein 2A |
|
| chr7_+_48088596 Show fit | 9.23 |
ENST00000416681.5
ENST00000331803.8 ENST00000432131.5 |
uridine phosphorylase 1 |
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 38.5 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.2 | 23.8 | GO:0070268 | cornification(GO:0070268) |
| 0.8 | 22.8 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 3.6 | 21.8 | GO:0061143 | alveolar primary septum development(GO:0061143) |
| 0.2 | 20.7 | GO:0030574 | collagen catabolic process(GO:0030574) |
| 0.6 | 16.2 | GO:2000404 | regulation of T cell migration(GO:2000404) |
| 1.3 | 15.7 | GO:0010820 | positive regulation of T cell chemotaxis(GO:0010820) |
| 0.1 | 14.9 | GO:0002377 | immunoglobulin production(GO:0002377) |
| 2.8 | 14.1 | GO:0090362 | positive regulation of platelet-derived growth factor production(GO:0090362) |
| 2.3 | 14.1 | GO:0002225 | positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 52.3 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.0 | 34.8 | GO:0005615 | extracellular space(GO:0005615) |
| 1.3 | 25.8 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 0.1 | 19.6 | GO:0001726 | ruffle(GO:0001726) |
| 0.2 | 19.5 | GO:1904724 | tertiary granule lumen(GO:1904724) |
| 0.1 | 17.8 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.1 | 16.9 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 2.5 | 14.7 | GO:0097149 | centralspindlin complex(GO:0097149) |
| 2.0 | 14.1 | GO:0097209 | epidermal lamellar body(GO:0097209) |
| 2.0 | 13.9 | GO:0005610 | laminin-5 complex(GO:0005610) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 96.0 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 3.5 | 24.8 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) |
| 1.1 | 22.8 | GO:0050786 | RAGE receptor binding(GO:0050786) |
| 1.0 | 17.6 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.3 | 15.8 | GO:0051183 | vitamin transporter activity(GO:0051183) |
| 0.1 | 15.6 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.1 | 15.1 | GO:0008017 | microtubule binding(GO:0008017) |
| 4.2 | 12.7 | GO:0004850 | uridine phosphorylase activity(GO:0004850) |
| 0.2 | 10.3 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.1 | 10.2 | GO:0008201 | heparin binding(GO:0008201) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 83.8 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.2 | 61.3 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.1 | 37.0 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.3 | 21.3 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 1.1 | 20.2 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.4 | 16.2 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.2 | 13.4 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.1 | 11.1 | PID BCR 5PATHWAY | BCR signaling pathway |
| 0.2 | 10.6 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.3 | 9.7 | SA FAS SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 31.2 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.1 | 19.6 | REACTOME PPARA ACTIVATES GENE EXPRESSION | Genes involved in PPARA Activates Gene Expression |
| 0.3 | 17.7 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.1 | 13.2 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.7 | 13.1 | REACTOME PYRIMIDINE CATABOLISM | Genes involved in Pyrimidine catabolism |
| 0.1 | 11.4 | REACTOME CELL JUNCTION ORGANIZATION | Genes involved in Cell junction organization |
| 0.3 | 9.7 | REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
| 0.0 | 9.7 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.2 | 9.4 | REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS | Genes involved in TGF-beta receptor signaling activates SMADs |
| 0.4 | 9.1 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |