Project
Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)
Navigation
Downloads
Results for BPTF
Z-value: 1.75
Motif logo
Transcription factors associated with BPTF
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| BPTF | hg38_v1_chr17_+_67825664_67825729 | 0.56 | 1.4e-03 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of BPTF
| Promoter | Score | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chrY_+_2841864 Show fit | 21.03 |
ENST00000430575.1
|
ribosomal protein S4 Y-linked 1 |
|
| chr16_-_28610032 Show fit | 13.48 |
ENST00000567512.1
|
sulfotransferase family 1A member 1 |
|
| chr4_-_16084002 Show fit | 10.86 |
ENST00000447510.7
|
prominin 1 |
|
| chr3_-_19946970 Show fit | 8.78 |
ENST00000344838.8
|
EF-hand domain family member B |
|
| chr19_+_41114430 Show fit | 8.19 |
ENST00000331105.7
|
cytochrome P450 family 2 subfamily F member 1 |
|
| chrY_+_20756103 Show fit | 7.37 |
ENST00000629237.2
|
ribosomal protein S4 Y-linked 2 |
|
| chr10_-_59753388 Show fit | 6.74 |
ENST00000430431.5
|
myoregulin |
|
| chr17_+_9576627 Show fit | 6.55 |
ENST00000396219.7
ENST00000352665.10 |
cilia and flagella associated protein 52 |
|
| chr12_-_68302872 Show fit | 6.01 |
ENST00000539972.5
|
Mdm1 nuclear protein |
|
| chr20_+_58150896 Show fit | 5.69 |
ENST00000371168.4
|
chromosome 20 open reading frame 85 |
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 22.1 | GO:0009812 | flavonoid metabolic process(GO:0009812) |
| 0.1 | 20.1 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
| 0.5 | 17.4 | GO:0070286 | axonemal dynein complex assembly(GO:0070286) |
| 0.1 | 16.2 | GO:0006367 | transcription initiation from RNA polymerase II promoter(GO:0006367) |
| 2.3 | 11.3 | GO:1902080 | regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081) |
| 1.6 | 11.0 | GO:2000768 | positive regulation of nephron tubule epithelial cell differentiation(GO:2000768) |
| 0.5 | 10.9 | GO:0019373 | epoxygenase P450 pathway(GO:0019373) |
| 0.5 | 8.2 | GO:1902260 | negative regulation of delayed rectifier potassium channel activity(GO:1902260) |
| 0.0 | 6.2 | GO:0006413 | translational initiation(GO:0006413) |
| 0.5 | 6.0 | GO:0046600 | negative regulation of centriole replication(GO:0046600) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 31.4 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.2 | 20.7 | GO:0005930 | axoneme(GO:0005930) ciliary plasm(GO:0097014) |
| 0.1 | 15.0 | GO:0032993 | protein-DNA complex(GO:0032993) |
| 0.3 | 11.2 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.1 | 8.6 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.1 | 7.2 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.2 | 5.5 | GO:0036038 | MKS complex(GO:0036038) |
| 0.1 | 4.8 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.2 | 4.6 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.9 | 4.5 | GO:0072534 | perineuronal net(GO:0072534) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 33.4 | GO:0019843 | rRNA binding(GO:0019843) |
| 3.1 | 18.4 | GO:0047894 | flavonol 3-sulfotransferase activity(GO:0047894) |
| 0.7 | 15.6 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.5 | 10.9 | GO:0008392 | arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392) |
| 0.0 | 8.1 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.1 | 7.8 | GO:0042805 | actinin binding(GO:0042805) |
| 0.1 | 7.2 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 2.4 | 7.1 | GO:0004556 | alpha-amylase activity(GO:0004556) |
| 0.9 | 5.7 | GO:0004127 | cytidylate kinase activity(GO:0004127) |
| 0.3 | 5.5 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 18.4 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.1 | 5.7 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.1 | 4.1 | PID BMP PATHWAY | BMP receptor signaling |
| 0.0 | 2.5 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 2.4 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.1 | 2.0 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
| 0.1 | 1.9 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.1 | 1.9 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.0 | 1.9 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.0 | 1.9 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 25.0 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 1.0 | 24.8 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 1.6 | 18.1 | REACTOME DIGESTION OF DIETARY CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
| 0.2 | 16.1 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.6 | 10.2 | REACTOME XENOBIOTICS | Genes involved in Xenobiotics |
| 0.0 | 8.8 | REACTOME GENERIC TRANSCRIPTION PATHWAY | Genes involved in Generic Transcription Pathway |
| 0.2 | 4.3 | REACTOME AMINE DERIVED HORMONES | Genes involved in Amine-derived hormones |
| 0.1 | 4.1 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.1 | 4.1 | REACTOME RNA POL III TRANSCRIPTION | Genes involved in RNA Polymerase III Transcription |
| 0.1 | 3.0 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |