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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for CACAGUG

Z-value: 0.43

Motif logo

miRNA associated with seed CACAGUG

NamemiRBASE accession
MIMAT0000424
MIMAT0022844
MIMAT0018109

Activity profile of CACAGUG motif

Sorted Z-values of CACAGUG motif

Network of associatons between targets according to the STRING database.

First level regulatory network of CACAGUG

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr20_-_7940444 1.30 ENST00000378789.4
hydroxyacid oxidase 1
chr4_-_107036302 0.68 ENST00000285311.8
dickkopf WNT signaling pathway inhibitor 2
chr20_-_43189733 0.60 ENST00000373187.5
ENST00000356100.6
ENST00000373184.5
ENST00000373190.5
protein tyrosine phosphatase receptor type T
chr5_-_157575767 0.53 ENST00000257527.9
ADAM metallopeptidase domain 19
chr11_-_123654581 0.50 ENST00000392770.6
ENST00000530277.5
ENST00000299333.8
sodium voltage-gated channel beta subunit 3
chr4_+_5051471 0.43 ENST00000282908.10
serine/threonine kinase 32B
chr2_+_6917404 0.42 ENST00000320892.11
ring finger protein 144A
chr6_+_20401864 0.39 ENST00000346618.8
ENST00000613242.4
E2F transcription factor 3
chr16_+_66844914 0.39 ENST00000394069.3
carbonic anhydrase 7
chr15_+_28885955 0.37 ENST00000558402.5
ENST00000683413.1
ENST00000558330.5
amyloid beta precursor protein binding family A member 2
chr17_-_52159983 0.35 ENST00000575181.1
ENST00000570565.5
ENST00000442502.6
carbonic anhydrase 10
chr12_+_3491189 0.34 ENST00000382622.4
protein arginine methyltransferase 8
chrX_-_3713593 0.34 ENST00000262848.6
protein kinase X-linked
chr20_-_51802509 0.33 ENST00000371539.7
ENST00000217086.9
spalt like transcription factor 4
chr10_-_70170466 0.32 ENST00000373239.2
ENST00000373241.9
ENST00000373242.6
secretion associated Ras related GTPase 1A
chr3_+_139935176 0.32 ENST00000458420.7
calsyntenin 2
chr11_-_30016945 0.32 ENST00000328224.7
potassium voltage-gated channel subfamily A member 4
chrX_+_65488735 0.31 ENST00000338957.4
zinc finger CCCH-type containing 12B
chr14_-_59465327 0.29 ENST00000395116.1
G protein-coupled receptor 135
chr5_-_140346596 0.28 ENST00000230990.7
heparin binding EGF like growth factor
chr3_+_10992717 0.28 ENST00000642767.1
ENST00000425938.6
ENST00000642515.1
ENST00000643498.1
ENST00000646072.1
ENST00000646570.1
ENST00000287766.10
ENST00000645281.1
ENST00000642820.1
ENST00000645054.1
ENST00000642735.1
ENST00000646022.1
ENST00000645776.1
ENST00000645592.1
ENST00000646924.1
ENST00000645974.1
ENST00000644314.1
ENST00000642639.1
ENST00000646060.1
ENST00000642201.1
ENST00000646487.1
ENST00000647194.1
ENST00000646088.1
solute carrier family 6 member 1
chr7_+_139231225 0.28 ENST00000473989.8
ubinuclein 2
chr17_-_55421818 0.28 ENST00000262065.8
ENST00000649377.1
monocyte to macrophage differentiation associated
chr3_+_36380477 0.28 ENST00000457375.6
ENST00000273183.8
ENST00000434649.1
SH3 and cysteine rich domain
chrX_-_54357993 0.27 ENST00000375169.7
ENST00000354646.6
WNK lysine deficient protein kinase 3
chr7_+_6104881 0.27 ENST00000306177.9
ENST00000465073.6
ubiquitin specific peptidase 42
chr5_-_180353317 0.27 ENST00000253778.13
glutamine-fructose-6-phosphate transaminase 2
chr6_+_117907226 0.26 ENST00000360388.9
solute carrier family 35 member F1
chr22_-_27801712 0.26 ENST00000302326.5
MN1 proto-oncogene, transcriptional regulator
chr11_+_14643782 0.26 ENST00000282096.9
phosphodiesterase 3B
chrX_+_16786421 0.25 ENST00000398155.4
ENST00000380122.10
taxilin gamma
chr16_-_4538819 0.25 ENST00000564828.5
cell death inducing p53 target 1
chr12_+_54549586 0.25 ENST00000243052.8
phosphodiesterase 1B
chr5_+_157460173 0.25 ENST00000435489.7
ENST00000311946.8
NIPA like domain containing 4
chrX_+_105822531 0.24 ENST00000243300.14
ENST00000536164.5
Nik related kinase
chr19_+_19211949 0.24 ENST00000252575.11
neurocan
chr19_-_344786 0.24 ENST00000264819.7
MIER family member 2
chr4_+_114598738 0.23 ENST00000507710.1
ENST00000310836.11
UDP glycosyltransferase 8
chr7_-_27143672 0.23 ENST00000222726.4
homeobox A5
chr19_+_51311638 0.23 ENST00000270642.9
IgLON family member 5
chr16_+_77788554 0.22 ENST00000302536.3
vesicle amine transport 1 like
chr21_-_43427131 0.22 ENST00000270162.8
salt inducible kinase 1
chr1_+_203305510 0.22 ENST00000290551.5
BTG anti-proliferation factor 2
chr14_-_53152371 0.21 ENST00000323669.10
DDHD domain containing 1
chr12_+_113057687 0.21 ENST00000257600.3
deltex E3 ubiquitin ligase 1
chr9_+_116153783 0.21 ENST00000328252.4
pappalysin 1
chr8_+_133191060 0.21 ENST00000519433.1
ENST00000517423.5
ENST00000220856.6
cellular communication network factor 4
chr2_-_100104530 0.20 ENST00000432037.5
ENST00000673232.1
ENST00000423966.6
ENST00000409236.6
AF4/FMR2 family member 3
chr9_+_113876282 0.20 ENST00000374126.9
ENST00000615615.4
ENST00000288466.11
zinc finger protein 618
chr2_-_40452046 0.19 ENST00000406785.6
solute carrier family 8 member A1
chr12_+_78864768 0.19 ENST00000261205.9
ENST00000457153.6
synaptotagmin 1
chr5_+_14664653 0.19 ENST00000284274.5
OTU deubiquitinase with linear linkage specificity
chr17_+_40287861 0.19 ENST00000209728.9
ENST00000580824.5
ENST00000577249.1
ENST00000649662.1
cell division cycle 6
chr22_-_37427433 0.19 ENST00000452946.1
ENST00000402918.7
extracellular leucine rich repeat and fibronectin type III domain containing 2
extracellular leucine rich repeat and fibronectin type III domain containing 2
chr7_+_24573415 0.19 ENST00000409761.5
ENST00000222644.10
ENST00000396475.6
membrane palmitoylated protein 6
chr15_-_55917129 0.19 ENST00000338963.6
ENST00000508342.5
NEDD4 E3 ubiquitin protein ligase
chr12_+_54028433 0.19 ENST00000243108.5
homeobox C6
chr1_+_76074698 0.19 ENST00000328299.4
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr22_+_20917398 0.18 ENST00000354336.8
CRK like proto-oncogene, adaptor protein
chr5_-_1523900 0.18 ENST00000283415.4
lysophosphatidylcholine acyltransferase 1
chr8_-_8893548 0.18 ENST00000276282.7
malignant fibrous histiocytoma amplified sequence 1
chr8_+_1973668 0.18 ENST00000320248.4
kelch repeat and BTB domain containing 11
chr16_-_88941198 0.18 ENST00000327483.9
ENST00000564416.1
CBFA2/RUNX1 partner transcriptional co-repressor 3
chr4_-_173530219 0.18 ENST00000359562.4
heart and neural crest derivatives expressed 2
chr14_-_29927801 0.17 ENST00000331968.11
protein kinase D1
chr17_+_12665882 0.17 ENST00000425538.6
myocardin
chr4_+_139301478 0.17 ENST00000296543.10
ENST00000398947.1
N-alpha-acetyltransferase 15, NatA auxiliary subunit
chr22_-_36703723 0.17 ENST00000300105.7
calcium voltage-gated channel auxiliary subunit gamma 2
chr9_-_127980976 0.17 ENST00000373095.6
family with sequence similarity 102 member A
chrX_+_150983299 0.17 ENST00000325307.12
high mobility group box 3
chr1_-_179229671 0.16 ENST00000502732.6
ENST00000392043.4
ABL proto-oncogene 2, non-receptor tyrosine kinase
chr19_+_40717091 0.16 ENST00000263370.3
inositol-trisphosphate 3-kinase C
chr5_-_132963621 0.16 ENST00000265343.10
AF4/FMR2 family member 4
chr16_-_4242068 0.16 ENST00000399609.7
sarcalumenin
chr13_+_112968496 0.16 ENST00000397030.5
MCF.2 cell line derived transforming sequence like
chrX_-_25015924 0.16 ENST00000379044.5
aristaless related homeobox
chr22_-_38844020 0.16 ENST00000333039.4
neuronal pentraxin receptor
chrX_+_49922605 0.16 ENST00000376088.7
chloride voltage-gated channel 5
chr17_-_48615261 0.16 ENST00000239144.5
homeobox B8
chr10_+_68560317 0.16 ENST00000373644.5
tet methylcytosine dioxygenase 1
chr5_-_58460076 0.16 ENST00000274289.8
ENST00000617412.1
polo like kinase 2
chr19_+_19385815 0.16 ENST00000494516.6
ENST00000360315.7
GATA zinc finger domain containing 2A
chr22_+_39502237 0.16 ENST00000325301.7
mitochondrial elongation factor 1
chr8_-_80874771 0.15 ENST00000327835.7
zinc finger protein 704
chr9_-_137302264 0.15 ENST00000356628.4
NOTCH regulated ankyrin repeat protein
chr18_+_52340179 0.15 ENST00000442544.7
DCC netrin 1 receptor
chr9_-_23821275 0.15 ENST00000380110.8
ELAV like RNA binding protein 2
chr21_+_31873010 0.15 ENST00000270112.7
hormonally up-regulated Neu-associated kinase
chr12_+_103587266 0.15 ENST00000388887.7
stabilin 2
chr4_-_138242325 0.14 ENST00000280612.9
solute carrier family 7 member 11
chr1_+_215082731 0.14 ENST00000444842.7
potassium two pore domain channel subfamily K member 2
chr7_-_31340678 0.14 ENST00000297142.4
neuronal differentiation 6
chr19_+_1285859 0.14 ENST00000215368.4
ephrin A2
chr15_+_73052449 0.14 ENST00000261908.11
neogenin 1
chr7_+_21428023 0.14 ENST00000432066.2
ENST00000222584.8
Sp4 transcription factor
chrX_+_14529516 0.14 ENST00000218075.9
glycine receptor alpha 2
chr3_-_39153512 0.14 ENST00000273153.10
cysteine and serine rich nuclear protein 1
chr4_+_113049616 0.14 ENST00000504454.5
ENST00000357077.9
ENST00000394537.7
ENST00000672779.1
ENST00000264366.10
ankyrin 2
chr5_+_65722190 0.14 ENST00000380985.10
ENST00000502464.5
neurolysin
chr4_+_159267737 0.14 ENST00000264431.8
Rap guanine nucleotide exchange factor 2
chr19_+_49591170 0.13 ENST00000418929.7
proline rich 12
chr7_-_139777986 0.13 ENST00000406875.8
homeodomain interacting protein kinase 2
chr1_+_70411180 0.13 ENST00000411986.6
cystathionine gamma-lyase
chr12_+_31959406 0.13 ENST00000540924.5
ENST00000312561.9
retroelement silencing factor 1
chr6_-_107115493 0.13 ENST00000369042.6
BEN domain containing 3
chr2_+_191678122 0.13 ENST00000425611.9
ENST00000410026.7
nucleic acid binding protein 1
chr17_-_7329266 0.13 ENST00000571887.5
ENST00000315614.11
ENST00000399464.7
ENST00000570460.5
neuralized E3 ubiquitin protein ligase 4
chr3_-_171460368 0.13 ENST00000436636.7
ENST00000465393.1
ENST00000341852.10
TRAF2 and NCK interacting kinase
chr3_-_24494791 0.13 ENST00000431815.5
ENST00000356447.9
ENST00000418247.1
ENST00000416420.5
ENST00000396671.7
thyroid hormone receptor beta
chr9_+_114155526 0.13 ENST00000356083.8
collagen type XXVII alpha 1 chain
chr5_+_153490655 0.13 ENST00000518142.5
ENST00000285900.10
glutamate ionotropic receptor AMPA type subunit 1
chr22_+_45671798 0.13 ENST00000381061.8
ENST00000252934.10
ataxin 10
chrX_-_80809854 0.12 ENST00000373275.5
bromodomain and WD repeat domain containing 3
chr2_-_53859929 0.12 ENST00000394705.3
ENST00000406625.6
G protein-coupled receptor 75
ankyrin repeat and SOCS box containing 3
chr3_-_21751189 0.12 ENST00000281523.8
zinc finger protein 385D
chr2_-_226799806 0.12 ENST00000305123.6
insulin receptor substrate 1
chr15_+_40929338 0.12 ENST00000249749.7
delta like canonical Notch ligand 4
chr11_-_74398378 0.12 ENST00000298198.5
phosphoglucomutase 2 like 1
chr17_+_49788672 0.12 ENST00000454930.6
ENST00000259021.9
ENST00000509773.5
ENST00000510819.5
ENST00000424009.6
lysine acetyltransferase 7
chr10_+_125719689 0.12 ENST00000337623.7
ENST00000356792.9
erythroid differentiation regulatory factor 1
chr1_-_34929574 0.12 ENST00000373347.6
DLG associated protein 3
chr6_+_135851681 0.12 ENST00000308191.11
phosphodiesterase 7B
chr18_-_268019 0.12 ENST00000631280.2
ENST00000616322.4
ENST00000261600.11
THO complex 1
chr2_-_118847638 0.12 ENST00000295206.7
engrailed homeobox 1
chr1_-_154502402 0.12 ENST00000304760.3
Src homology 2 domain containing E
chr20_+_10218808 0.12 ENST00000254976.7
ENST00000304886.6
synaptosome associated protein 25
chr7_+_155458129 0.12 ENST00000297375.4
engrailed homeobox 2
chr6_-_46325641 0.12 ENST00000330430.10
ENST00000405162.2
regulator of calcineurin 2
chr2_+_30231524 0.11 ENST00000395323.9
ENST00000406087.5
ENST00000404397.5
LBH regulator of WNT signaling pathway
chr17_+_29390326 0.11 ENST00000261716.8
TAO kinase 1
chr13_-_49792675 0.11 ENST00000261667.8
karyopherin subunit alpha 3
chr13_-_102401599 0.11 ENST00000376131.8
fibroblast growth factor 14
chr19_+_48393657 0.11 ENST00000263269.4
glutamate ionotropic receptor NMDA type subunit 2D
chr6_-_119078642 0.11 ENST00000621231.4
ENST00000338891.12
family with sequence similarity 184 member A
chr1_+_54053573 0.11 ENST00000234827.6
transcription elongation factor A N-terminal and central domain containing 2
chr17_+_49495286 0.11 ENST00000172229.8
nerve growth factor receptor
chr17_+_27471999 0.11 ENST00000583370.5
ENST00000509603.6
ENST00000268763.10
ENST00000398988.7
kinase suppressor of ras 1
chr3_+_50611871 0.11 ENST00000446044.5
MAPK activated protein kinase 3
chr1_+_35931076 0.11 ENST00000397828.3
ENST00000373191.9
argonaute RISC catalytic component 3
chr15_-_74433942 0.11 ENST00000543145.6
ENST00000261918.9
semaphorin 7A (John Milton Hagen blood group)
chr11_-_60906564 0.11 ENST00000541371.5
ENST00000227524.9
pre-mRNA processing factor 19
chr2_-_24360299 0.10 ENST00000361999.7
intersectin 2
chr12_-_12267003 0.10 ENST00000535731.1
ENST00000261349.9
LDL receptor related protein 6
chr9_-_132944600 0.10 ENST00000490179.3
ENST00000643583.1
ENST00000298552.9
ENST00000643072.1
ENST00000642745.1
ENST00000647462.1
ENST00000643875.1
ENST00000642627.1
ENST00000475903.6
ENST00000642617.1
ENST00000642646.1
ENST00000646625.1
ENST00000645150.1
ENST00000645129.1
ENST00000403810.6
ENST00000643691.1
ENST00000644097.1
TSC complex subunit 1
chr10_+_110497898 0.10 ENST00000369583.4
dual specificity phosphatase 5
chr6_+_125790922 0.10 ENST00000453302.5
ENST00000417494.5
ENST00000392477.7
ENST00000229634.13
nuclear receptor coactivator 7
chr16_-_352714 0.10 ENST00000262320.8
axin 1
chr12_-_31591129 0.10 ENST00000389082.10
DENN domain containing 5B
chr5_+_132813283 0.10 ENST00000378693.4
sosondowah ankyrin repeat domain family member A
chr3_-_179071742 0.10 ENST00000311417.7
ENST00000652290.1
zinc finger matrin-type 3
chrX_+_37571569 0.10 ENST00000614025.4
ENST00000378621.7
ENST00000378619.4
LanC like 3
chr2_+_157257687 0.10 ENST00000259056.5
polypeptide N-acetylgalactosaminyltransferase 5
chr8_-_90646074 0.10 ENST00000458549.7
transmembrane protein 64
chr9_-_136050502 0.10 ENST00000371753.5
NACC family member 2
chr13_-_75482151 0.10 ENST00000377636.8
TBC1 domain family member 4
chr2_+_107826892 0.10 ENST00000408999.4
RANBP2 like and GRIP domain containing 4
chr13_+_51584435 0.10 ENST00000612477.1
ENST00000298125.7
WD repeat and FYVE domain containing 2
chr14_+_102777461 0.10 ENST00000560371.5
ENST00000347662.8
TNF receptor associated factor 3
chr21_-_26967057 0.10 ENST00000284987.6
ADAM metallopeptidase with thrombospondin type 1 motif 5
chr10_+_102714595 0.10 ENST00000602647.5
ENST00000602439.5
ENST00000602764.5
ENST00000369893.10
sideroflexin 2
chr6_+_41638438 0.10 ENST00000441667.5
ENST00000230321.11
ENST00000373050.8
ENST00000446650.1
ENST00000435476.1
MyoD family inhibitor
chr3_+_119468952 0.09 ENST00000476573.5
ENST00000295588.9
protein O-glucosyltransferase 1
chr21_-_37916440 0.09 ENST00000609713.2
potassium inwardly rectifying channel subfamily J member 6
chr16_-_25257805 0.09 ENST00000328086.12
zinc finger with KRAB and SCAN domains 2
chr2_-_43226594 0.09 ENST00000282388.4
ZFP36 ring finger protein like 2
chr10_+_96043394 0.09 ENST00000403870.7
ENST00000265992.9
ENST00000465148.3
cyclin J
chr5_+_144205250 0.09 ENST00000507359.3
potassium channel tetramerization domain containing 16
chr18_+_56651335 0.09 ENST00000589935.1
ENST00000254442.8
ENST00000357574.7
WD repeat domain 7
chr12_+_70366277 0.09 ENST00000258111.5
potassium calcium-activated channel subfamily M regulatory beta subunit 4
chr20_-_62407274 0.09 ENST00000279101.9
Cdk5 and Abl enzyme substrate 2
chr1_+_100896060 0.09 ENST00000370112.8
ENST00000357650.9
solute carrier family 30 member 7
chr7_-_27174274 0.09 ENST00000283921.5
homeobox A10
chr5_+_7396099 0.09 ENST00000338316.9
adenylate cyclase 2
chr12_-_42144823 0.09 ENST00000398675.8
glucoside xylosyltransferase 1
chr3_-_86991135 0.09 ENST00000398399.7
vestigial like family member 3
chr3_+_123067016 0.09 ENST00000316218.12
protein disulfide isomerase family A member 5
chr1_-_18956669 0.08 ENST00000455833.7
intermediate filament family orphan 2
chr8_-_140635617 0.08 ENST00000220592.10
argonaute RISC catalytic component 2
chr11_+_120210991 0.08 ENST00000328965.9
out at first homolog
chrX_-_130268883 0.08 ENST00000447817.1
ENST00000370978.9
zinc finger protein 280C
chr15_+_40440889 0.08 ENST00000416165.6
bromo adjacent homology domain containing 1
chr2_-_50347710 0.08 ENST00000342183.9
ENST00000401710.5
neurexin 1
chr17_-_49414871 0.08 ENST00000504124.6
ENST00000300408.8
ENST00000614445.5
prohibitin
chr19_+_15107369 0.08 ENST00000342784.7
ENST00000597977.5
ENST00000600440.5
synapse defective Rho GTPase homolog 1
chrX_+_73563190 0.08 ENST00000373504.10
ENST00000373502.9
cysteine rich hydrophobic domain 1
chr2_-_190534700 0.08 ENST00000409150.8
nuclear envelope integral membrane protein 2
chr19_+_37907200 0.08 ENST00000222345.11
signal induced proliferation associated 1 like 3
chr12_-_122966438 0.08 ENST00000344275.11
ENST00000442833.6
ENST00000280560.13
ENST00000540285.5
ENST00000346530.9
ATP binding cassette subfamily B member 9
chr12_-_77065526 0.08 ENST00000547316.1
ENST00000416496.6
ENST00000550669.5
ENST00000322886.12
E2F transcription factor 7
chr1_-_205356894 0.08 ENST00000367155.8
kelch domain containing 8A
chr2_-_206086057 0.08 ENST00000403263.6
INO80 complex subunit D
chrX_-_40735476 0.08 ENST00000324817.6
mediator complex subunit 14
chr4_+_3074661 0.08 ENST00000355072.11
huntingtin
chr18_+_22169580 0.08 ENST00000269216.10
GATA binding protein 6
chr6_-_48111132 0.08 ENST00000398738.3
ENST00000679966.1
ENST00000339488.9
patched domain containing 4
chr21_-_38498415 0.08 ENST00000398905.5
ENST00000398907.5
ENST00000453032.6
ENST00000288319.12
ETS transcription factor ERG
chr9_+_126613922 0.08 ENST00000526117.6
ENST00000373474.9
ENST00000355497.10
LIM homeobox transcription factor 1 beta
chr11_-_31811314 0.08 ENST00000640368.2
ENST00000379123.10
ENST00000379115.9
ENST00000419022.6
ENST00000643871.1
ENST00000640610.1
ENST00000639034.2
paired box 6
chr11_+_112961402 0.08 ENST00000613217.4
ENST00000316851.12
ENST00000620046.4
ENST00000531044.5
ENST00000529356.5
neural cell adhesion molecule 1
chr8_-_10839818 0.07 ENST00000554914.1
PIN2 (TERF1) interacting telomerase inhibitor 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0009441 glycolate metabolic process(GO:0009441)
0.1 0.3 GO:0051939 gamma-aminobutyric acid import(GO:0051939)
0.1 0.2 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.1 0.4 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.1 0.2 GO:0060435 bronchiole development(GO:0060435)
0.1 0.2 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.2 GO:0044007 negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010768) transmission of virus(GO:0019089) dissemination or transmission of symbiont from host(GO:0044007) dissemination or transmission of organism from other organism involved in symbiotic interaction(GO:0051821)
0.1 0.5 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 0.2 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560) negative regulation of beta-amyloid clearance(GO:1900222) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.1 0.3 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.3 GO:0010868 negative regulation of triglyceride biosynthetic process(GO:0010868)
0.1 0.2 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0 0.2 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.1 GO:0044691 tooth eruption(GO:0044691)
0.0 0.1 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0 0.2 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0 0.3 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.2 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.0 0.1 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0 0.1 GO:0072720 response to dithiothreitol(GO:0072720)
0.0 0.2 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.2 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.2 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.0 0.1 GO:0075732 viral penetration into host nucleus(GO:0075732) multi-organism nuclear import(GO:1902594)
0.0 0.3 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.2 GO:0003219 cardiac right ventricle formation(GO:0003219) visceral serous pericardium development(GO:0061032)
0.0 0.1 GO:0048320 commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898) axial mesoderm formation(GO:0048320) canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.3 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.3 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.3 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.1 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 0.3 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.1 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377) positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0 0.4 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.2 GO:0006682 protein localization to paranode region of axon(GO:0002175) galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.0 0.1 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0 0.1 GO:0032912 negative regulation of transforming growth factor beta2 production(GO:0032912)
0.0 0.2 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.1 GO:0030221 basophil differentiation(GO:0030221)
0.0 0.1 GO:1904674 positive regulation of somatic stem cell population maintenance(GO:1904674)
0.0 0.1 GO:0045041 B cell cytokine production(GO:0002368) protein import into mitochondrial intermembrane space(GO:0045041)
0.0 0.1 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.1 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.1 GO:0051029 rRNA transport(GO:0051029)
0.0 0.1 GO:0045917 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.0 0.1 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.1 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.2 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:1904744 positive regulation of telomeric DNA binding(GO:1904744)
0.0 0.1 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.2 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.1 GO:0071962 mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.0 0.1 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.0 0.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.3 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.1 GO:0061073 ciliary body morphogenesis(GO:0061073) endocardial cushion cell differentiation(GO:0061443)
0.0 0.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.3 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.2 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0048318 axial mesoderm development(GO:0048318)
0.0 0.1 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.0 GO:0003358 noradrenergic neuron development(GO:0003358)
0.0 0.0 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.0 0.0 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.0 GO:0097360 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907)
0.0 0.1 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.1 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.0 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258)
0.0 0.1 GO:2000504 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.4 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.1 GO:0090107 regulation of high-density lipoprotein particle assembly(GO:0090107)
0.0 0.0 GO:0021592 fourth ventricle development(GO:0021592)
0.0 0.1 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.1 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.0 GO:0035627 ceramide transport(GO:0035627)
0.0 0.0 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.0 0.1 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.0 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 0.2 GO:0061000 negative regulation of dendritic spine development(GO:0061000)
0.0 0.2 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.3 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.1 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.1 GO:0044308 axonal spine(GO:0044308)
0.0 0.1 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.0 0.1 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 1.4 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.0 GO:0071750 dimeric IgA immunoglobulin complex(GO:0071750) secretory dimeric IgA immunoglobulin complex(GO:0071752) IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.1 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0003973 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.1 0.3 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1 0.3 GO:0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360)
0.1 0.2 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.1 0.6 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.8 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.5 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.2 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.3 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.3 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.1 GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
0.0 0.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.3 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.3 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.1 GO:0098808 mRNA cap binding(GO:0098808)
0.0 0.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0052858 peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.0 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.3 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.0 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.0 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.2 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.1 PID EPHA FWDPATHWAY EPHA forward signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.6 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.1 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.6 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.2 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.0 0.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects