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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for CDX1

Z-value: 0.58

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Transcription factors associated with CDX1

Gene Symbol Gene ID Gene Info
CDX1
ENSG00000113722.17 CDX1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CDX1hg38_v1_chr5_+_150166790_150166890,
hg38_v1_chr5_+_150166770_150166788		0.202.8e-01Click!

Activity profile of CDX1 motif

Sorted Z-values of CDX1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of CDX1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr4_+_68447453 1.90 ENST00000305363.9
TMPRSS11E
transmembrane serine protease 11E
chr3_+_190615308 1.77 ENST00000412080.1
IL1RAP
interleukin 1 receptor accessory protein
chr11_-_102955705 1.76 ENST00000615555.4
ENST00000340273.4
ENST00000260302.8
MMP13
matrix metallopeptidase 13
chr1_+_20589044 1.63 ENST00000375071.4
CDA
cytidine deaminase
chr1_-_152414256 1.54 ENST00000271835.3
CRNN
cornulin
chr5_-_39202991 1.39 ENST00000515010.5
FYB1
FYN binding protein 1
chr2_-_31138041 1.32 ENST00000324589.9
GALNT14
polypeptide N-acetylgalactosaminyltransferase 14
chr12_-_52385649 1.32 ENST00000257951.3
KRT84
keratin 84
chr10_-_88952763 1.16 ENST00000224784.10
ACTA2
actin alpha 2, smooth muscle
chr7_+_80638662 1.14 ENST00000394788.7
CD36
CD36 molecule
chrX_+_100644183 1.07 ENST00000640889.1
ENST00000373004.5
SRPX2
sushi repeat containing protein X-linked 2
chr17_-_41397600 1.02 ENST00000251645.3
KRT31
keratin 31
chr6_+_126340107 0.96 ENST00000368328.5
ENST00000368326.5
ENST00000368325.5
CENPW
centromere protein W
chr1_+_84164962 0.95 ENST00000614872.4
ENST00000394839.6
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr3_-_149377637 0.91 ENST00000305366.8
TM4SF1
transmembrane 4 L six family member 1
chr16_-_18876305 0.89 ENST00000563235.5
SMG1
SMG1 nonsense mediated mRNA decay associated PI3K related kinase
chr2_-_207166818 0.87 ENST00000423015.5
KLF7
Kruppel like factor 7
chr13_+_77535742 0.87 ENST00000377246.7
SCEL
sciellin
chr2_-_207167220 0.84 ENST00000421199.5
ENST00000457962.5
KLF7
Kruppel like factor 7
chr20_+_6767678 0.83 ENST00000378827.5
BMP2
bone morphogenetic protein 2
chr12_-_27971970 0.79 ENST00000395872.5
ENST00000201015.8
PTHLH
parathyroid hormone like hormone
chr2_+_33134620 0.78 ENST00000402934.5
ENST00000404525.5
ENST00000407925.5
LTBP1
latent transforming growth factor beta binding protein 1
chr1_+_84164370 0.77 ENST00000446538.5
ENST00000610703.4
ENST00000370682.7
ENST00000394838.6
ENST00000432111.5
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr17_-_59151794 0.77 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr2_+_33134579 0.75 ENST00000418533.6
LTBP1
latent transforming growth factor beta binding protein 1
chr12_-_47771029 0.73 ENST00000549151.5
ENST00000548919.5
RAPGEF3
Rap guanine nucleotide exchange factor 3
chr9_-_92482350 0.73 ENST00000375543.2
ASPN
asporin
chr3_+_172754457 0.73 ENST00000441497.6
ECT2
epithelial cell transforming 2
chr8_-_100706931 0.71 ENST00000520868.5
PABPC1
poly(A) binding protein cytoplasmic 1
chr9_+_74615582 0.68 ENST00000396204.2
RORB
RAR related orphan receptor B
chr17_-_43022350 0.66 ENST00000587173.5
ENST00000355653.8
VAT1
vesicle amine transport 1
chr5_-_16742221 0.66 ENST00000505695.5
MYO10
myosin X
chr11_+_111245725 0.66 ENST00000280325.7
C11orf53
chromosome 11 open reading frame 53
chr3_+_130931893 0.66 ENST00000504612.5
ATP2C1
ATPase secretory pathway Ca2+ transporting 1
chr4_-_22443110 0.65 ENST00000508133.5
ADGRA3
adhesion G protein-coupled receptor A3
chr12_-_27972725 0.65 ENST00000545234.6
PTHLH
parathyroid hormone like hormone
chr1_-_120054225 0.64 ENST00000602566.6
NOTCH2
notch receptor 2
chr18_-_12656716 0.58 ENST00000462226.1
ENST00000497844.6
ENST00000309836.9
ENST00000453447.6
SPIRE1
spire type actin nucleation factor 1
chr7_+_80638510 0.57 ENST00000433696.6
ENST00000538969.5
ENST00000544133.5
CD36
CD36 molecule
chr6_+_36678699 0.57 ENST00000405375.5
ENST00000244741.10
ENST00000373711.3
CDKN1A
cyclin dependent kinase inhibitor 1A
chr12_-_56934403 0.56 ENST00000293502.2
SDR9C7
short chain dehydrogenase/reductase family 9C member 7
chr6_+_31739948 0.56 ENST00000375755.8
ENST00000425703.5
ENST00000375750.9
ENST00000375703.7
ENST00000375740.7
MSH5
mutS homolog 5
chr11_-_5516690 0.55 ENST00000380184.2
UBQLNL
ubiquilin like
chr9_-_21482313 0.55 ENST00000448696.4
IFNE
interferon epsilon
chr7_+_80646436 0.54 ENST00000419819.2
CD36
CD36 molecule
chr13_+_52455972 0.54 ENST00000490903.5
ENST00000480747.1
CKAP2
cytoskeleton associated protein 2
chr3_+_101827982 0.53 ENST00000461724.5
ENST00000483180.5
ENST00000394054.6
NFKBIZ
NFKB inhibitor zeta
chr7_+_80638633 0.53 ENST00000447544.7
ENST00000482059.6
CD36
CD36 molecule
chr3_-_151329539 0.53 ENST00000325602.6
P2RY13
purinergic receptor P2Y13
chr1_+_40988513 0.53 ENST00000649215.1
CTPS1
CTP synthase 1
chr2_+_10123171 0.53 ENST00000615152.5
RRM2
ribonucleotide reductase regulatory subunit M2
chr8_+_22565236 0.52 ENST00000523900.5
SORBS3
sorbin and SH3 domain containing 3
chr1_+_178725147 0.52 ENST00000367634.6
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr1_-_120051714 0.51 ENST00000579475.7
NOTCH2
notch receptor 2
chr18_+_63777773 0.50 ENST00000447428.5
ENST00000546027.5
SERPINB7
serpin family B member 7
chr9_-_92482499 0.49 ENST00000375544.7
ASPN
asporin
chr11_+_117179127 0.48 ENST00000278951.11
SIDT2
SID1 transmembrane family member 2
chr17_+_59155726 0.48 ENST00000578777.5
ENST00000577457.1
ENST00000582995.5
ENST00000262293.9
ENST00000614081.1
PRR11
proline rich 11
chr5_+_36166556 0.48 ENST00000677886.1
SKP2
S-phase kinase associated protein 2
chr3_-_193554799 0.48 ENST00000295548.3
ATP13A4
ATPase 13A4
chr11_+_134069060 0.47 ENST00000534549.5
ENST00000441717.3
ENST00000299106.9
JAM3
junctional adhesion molecule 3
chrX_+_108044967 0.47 ENST00000415430.7
VSIG1
V-set and immunoglobulin domain containing 1
chr3_-_197260369 0.45 ENST00000658155.1
ENST00000453607.5
DLG1
discs large MAGUK scaffold protein 1
chr15_+_41774539 0.45 ENST00000514566.5
MAPKBP1
mitogen-activated protein kinase binding protein 1
chr11_-_11353241 0.45 ENST00000528848.3
CSNK2A3
casein kinase 2 alpha 3
chr17_+_44846318 0.44 ENST00000591513.5
HIGD1B
HIG1 hypoxia inducible domain family member 1B
chr1_+_153031195 0.44 ENST00000307098.5
SPRR1B
small proline rich protein 1B
chr11_+_28108248 0.44 ENST00000406787.7
ENST00000403099.5
ENST00000407364.8
METTL15
methyltransferase like 15
chr8_-_42207667 0.43 ENST00000352041.7
ENST00000679151.1
ENST00000679300.1
PLAT
plasminogen activator, tissue type
chrX_-_15664798 0.43 ENST00000380342.4
CLTRN
collectrin, amino acid transport regulator
chr3_-_197184131 0.43 ENST00000452595.5
DLG1
discs large MAGUK scaffold protein 1
chr14_-_67412112 0.42 ENST00000216446.9
PLEK2
pleckstrin 2
chr12_+_12891554 0.41 ENST00000014914.6
GPRC5A
G protein-coupled receptor class C group 5 member A
chr6_-_132763424 0.41 ENST00000532012.1
ENST00000525270.5
ENST00000530536.5
ENST00000524919.5
VNN2
vanin 2
chr18_+_63775395 0.41 ENST00000398019.7
SERPINB7
serpin family B member 7
chr7_+_74773962 0.41 ENST00000289473.10
NCF1
neutrophil cytosolic factor 1
chr8_-_42207557 0.40 ENST00000220809.9
ENST00000429089.6
ENST00000519510.5
ENST00000429710.6
ENST00000524009.5
PLAT
plasminogen activator, tissue type
chr18_+_63775369 0.40 ENST00000540675.5
SERPINB7
serpin family B member 7
chr10_+_100997040 0.40 ENST00000370223.7
LZTS2
leucine zipper tumor suppressor 2
chr5_+_96743536 0.40 ENST00000515663.5
CAST
calpastatin
chr10_-_49134021 0.40 ENST00000311787.6
FAM170B
family with sequence similarity 170 member B
chr4_-_70666492 0.40 ENST00000254801.9
ENST00000391614.7
JCHAIN
joining chain of multimeric IgA and IgM
chr1_+_178341445 0.39 ENST00000462775.5
RASAL2
RAS protein activator like 2
chr15_+_80441229 0.39 ENST00000533983.5
ENST00000527771.5
ENST00000525103.1
ARNT2
aryl hydrocarbon receptor nuclear translocator 2
chr14_-_106639589 0.39 ENST00000390630.3
IGHV4-61
immunoglobulin heavy variable 4-61
chr7_+_141764097 0.39 ENST00000247879.2
TAS2R3
taste 2 receptor member 3
chr3_-_33645433 0.39 ENST00000635664.1
ENST00000485378.6
ENST00000313350.10
ENST00000487200.5
CLASP2
cytoplasmic linker associated protein 2
chr4_-_151227881 0.39 ENST00000652233.1
ENST00000514152.5
SH3D19
SH3 domain containing 19
chr7_+_141790217 0.38 ENST00000247883.5
TAS2R5
taste 2 receptor member 5
chr9_+_128340474 0.38 ENST00000300456.5
SLC27A4
solute carrier family 27 member 4
chr6_-_47042260 0.37 ENST00000371243.2
ADGRF1
adhesion G protein-coupled receptor F1
chrX_+_108045050 0.37 ENST00000458383.1
ENST00000217957.10
VSIG1
V-set and immunoglobulin domain containing 1
chr8_+_38728550 0.37 ENST00000520340.5
ENST00000518415.5
TACC1
transforming acidic coiled-coil containing protein 1
chr18_-_26863187 0.37 ENST00000440832.7
AQP4
aquaporin 4
chr4_+_153152163 0.37 ENST00000676423.1
ENST00000675745.1
ENST00000676348.1
ENST00000676408.1
ENST00000674874.1
ENST00000675315.1
ENST00000675518.1
TRIM2
ENSG00000288637.1
tripartite motif containing 2
novel protein
chr8_-_37940103 0.37 ENST00000524298.1
ENST00000307599.5
GOT1L1
glutamic-oxaloacetic transaminase 1 like 1
chr15_+_41774459 0.37 ENST00000457542.7
ENST00000456763.6
MAPKBP1
mitogen-activated protein kinase binding protein 1
chr3_+_183265302 0.36 ENST00000465010.1
B3GNT5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr14_+_65411845 0.36 ENST00000556518.5
ENST00000557164.5
FUT8
fucosyltransferase 8
chr16_+_56638659 0.35 ENST00000290705.12
MT1A
metallothionein 1A
chr10_+_5446601 0.34 ENST00000449083.5
ENST00000380359.3
NET1
neuroepithelial cell transforming 1
chr6_-_116829037 0.34 ENST00000368549.7
ENST00000530250.1
ENST00000310357.8
GPRC6A
G protein-coupled receptor class C group 6 member A
chr15_+_71547226 0.33 ENST00000357769.4
ENST00000261862.7
THSD4
thrombospondin type 1 domain containing 4
chr5_-_128339191 0.33 ENST00000507835.5
FBN2
fibrillin 2
chr16_-_56668034 0.33 ENST00000569500.5
ENST00000379811.4
ENST00000444837.6
MT1G
metallothionein 1G
chr3_+_150408314 0.32 ENST00000361875.7
TSC22D2
TSC22 domain family member 2
chrX_+_12906639 0.32 ENST00000311912.5
TLR8
toll like receptor 8
chr17_-_10373002 0.31 ENST00000252172.9
ENST00000418404.8
MYH13
myosin heavy chain 13
chr19_-_15418979 0.31 ENST00000397410.10
ENST00000596195.5
ENST00000595067.1
ENST00000595465.6
ENST00000680649.1
ENST00000679638.1
ENST00000600247.5
AKAP8L
A-kinase anchoring protein 8 like
chr3_+_159069252 0.31 ENST00000640015.1
ENST00000476809.7
ENST00000485419.7
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chrX_+_12906612 0.31 ENST00000218032.7
TLR8
toll like receptor 8
chr2_-_162536955 0.30 ENST00000621889.1
KCNH7
potassium voltage-gated channel subfamily H member 7
chr13_+_31945826 0.30 ENST00000647500.1
FRY
FRY microtubule binding protein
chr3_-_37174578 0.30 ENST00000336686.9
LRRFIP2
LRR binding FLII interacting protein 2
chr7_-_97872394 0.29 ENST00000455086.5
ENST00000394308.8
ENST00000453600.5
ASNS
asparagine synthetase (glutamine-hydrolyzing)
chr14_-_23035223 0.29 ENST00000425762.2
PSMB5
proteasome 20S subunit beta 5
chr7_+_144000320 0.29 ENST00000641698.1
OR6B1
olfactory receptor family 6 subfamily B member 1
chr12_+_96912517 0.29 ENST00000457368.2
NEDD1
NEDD1 gamma-tubulin ring complex targeting factor
chr7_-_97872120 0.28 ENST00000394309.7
ENST00000414884.1
ENST00000442734.5
ASNS
asparagine synthetase (glutamine-hydrolyzing)
chr12_-_10172117 0.28 ENST00000545927.5
ENST00000309539.8
ENST00000432556.6
ENST00000544577.5
OLR1
oxidized low density lipoprotein receptor 1
chr7_+_77840122 0.28 ENST00000450574.5
ENST00000248550.7
PHTF2
putative homeodomain transcription factor 2
chr16_+_56657999 0.28 ENST00000568475.1
MT1F
metallothionein 1F
chr14_+_22040576 0.28 ENST00000390448.3
TRAV20
T cell receptor alpha variable 20
chr17_-_76570544 0.27 ENST00000640006.1
ENSG00000284526.1
novel protein
chr19_-_48993300 0.27 ENST00000323798.8
ENST00000263276.6
GYS1
glycogen synthase 1
chr8_+_22565655 0.27 ENST00000523965.5
SORBS3
sorbin and SH3 domain containing 3
chr16_+_56657924 0.27 ENST00000334350.7
MT1F
metallothionein 1F
chr5_+_141421020 0.26 ENST00000622044.1
ENST00000398587.7
PCDHGA11
protocadherin gamma subfamily A, 11
chr16_+_14833713 0.26 ENST00000287667.12
ENST00000620755.4
ENST00000610363.4
NOMO1
NODAL modulator 1
chrX_+_41689006 0.26 ENST00000378138.5
ENST00000620846.1
ENST00000649219.1
GPR34
G protein-coupled receptor 34
chr1_-_28058087 0.26 ENST00000373864.5
EYA3
EYA transcriptional coactivator and phosphatase 3
chr18_+_58149314 0.26 ENST00000435432.6
ENST00000357895.9
ENST00000586263.5
NEDD4L
NEDD4 like E3 ubiquitin protein ligase
chr3_-_197226351 0.26 ENST00000656428.1
DLG1
discs large MAGUK scaffold protein 1
chr5_+_87267792 0.25 ENST00000274376.11
RASA1
RAS p21 protein activator 1
chr15_+_51829644 0.25 ENST00000308580.12
TMOD3
tropomodulin 3
chr3_+_136022734 0.25 ENST00000334546.6
PPP2R3A
protein phosphatase 2 regulatory subunit B''alpha
chrX_+_41688967 0.25 ENST00000378142.9
GPR34
G protein-coupled receptor 34
chr14_+_88824621 0.25 ENST00000622513.4
ENST00000380656.7
ENST00000338104.10
ENST00000346301.8
ENST00000354441.10
ENST00000556651.5
ENST00000554686.5
TTC8
tetratricopeptide repeat domain 8
chrM_-_14669 0.25 ENST00000361681.2
MT-ND6
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6
chr14_-_91732059 0.25 ENST00000553329.5
ENST00000256343.8
CATSPERB
cation channel sperm associated auxiliary subunit beta
chr14_+_22147988 0.25 ENST00000390457.2
TRAV27
T cell receptor alpha variable 27
chr7_+_107583919 0.25 ENST00000491150.5
BCAP29
B cell receptor associated protein 29
chr2_+_135586250 0.25 ENST00000410054.5
ENST00000628915.2
R3HDM1
R3H domain containing 1
chr7_+_120988683 0.25 ENST00000340646.9
ENST00000310396.10
CPED1
cadherin like and PC-esterase domain containing 1
chr5_+_80035341 0.24 ENST00000350881.6
THBS4
thrombospondin 4
chr2_+_113005454 0.24 ENST00000259211.7
IL36A
interleukin 36 alpha
chr7_+_143959927 0.24 ENST00000624504.1
OR2F1
olfactory receptor family 2 subfamily F member 1
chr14_+_96256194 0.24 ENST00000216629.11
ENST00000553356.1
BDKRB1
bradykinin receptor B1
chr18_-_22417910 0.24 ENST00000391403.4
CTAGE1
cutaneous T cell lymphoma-associated antigen 1
chr19_-_12957198 0.24 ENST00000316939.3
GADD45GIP1
GADD45G interacting protein 1
chr7_+_106865474 0.24 ENST00000359195.3
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
chr8_+_2045058 0.24 ENST00000523438.1
MYOM2
myomesin 2
chr3_-_197260722 0.24 ENST00000654733.1
ENST00000661808.1
DLG1
discs large MAGUK scaffold protein 1
chr1_+_159587817 0.24 ENST00000255040.3
APCS
amyloid P component, serum
chr8_+_73991345 0.23 ENST00000284818.7
ENST00000518893.1
LY96
lymphocyte antigen 96
chr2_-_208129824 0.23 ENST00000282141.4
CRYGC
crystallin gamma C
chr8_-_143973520 0.23 ENST00000356346.7
PLEC
plectin
chr1_-_39883434 0.23 ENST00000541099.5
ENST00000441669.6
ENST00000316891.10
ENST00000537440.5
ENST00000372818.5
TRIT1
tRNA isopentenyltransferase 1
chr4_-_82844418 0.23 ENST00000503937.5
SEC31A
SEC31 homolog A, COPII coat complex component
chr10_-_32935511 0.23 ENST00000423113.5
ITGB1
integrin subunit beta 1
chr6_+_26087417 0.23 ENST00000357618.10
ENST00000309234.10
HFE
homeostatic iron regulator
chr12_+_18262730 0.22 ENST00000675017.1
PIK3C2G
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr16_+_21678514 0.22 ENST00000286149.8
ENST00000388958.8
OTOA
otoancorin
chr15_-_82806054 0.22 ENST00000541889.1
ENST00000334574.12
ENST00000561368.1
FSD2
fibronectin type III and SPRY domain containing 2
chr9_+_74497308 0.22 ENST00000376896.8
RORB
RAR related orphan receptor B
chr14_+_21918161 0.22 ENST00000390439.2
TRAV13-2
T cell receptor alpha variable 13-2
chr11_-_13496018 0.22 ENST00000529816.1
PTH
parathyroid hormone
chr2_+_161136901 0.22 ENST00000259075.6
ENST00000432002.5
TANK
TRAF family member associated NFKB activator
chr6_-_127900958 0.22 ENST00000434358.3
ENST00000630369.2
ENST00000368248.4
THEMIS
thymocyte selection associated
chr18_-_3845292 0.21 ENST00000400145.6
DLGAP1
DLG associated protein 1
chr16_+_56651885 0.21 ENST00000334346.3
ENST00000562399.1
MT1B
metallothionein 1B
chr2_-_88128049 0.21 ENST00000393750.3
ENST00000295834.8
FABP1
fatty acid binding protein 1
chr2_+_172928165 0.21 ENST00000535187.5
RAPGEF4
Rap guanine nucleotide exchange factor 4
chr17_-_58415628 0.20 ENST00000583753.5
RNF43
ring finger protein 43
chr4_-_69961007 0.20 ENST00000353151.3
CSN2
casein beta
chr22_+_17628828 0.20 ENST00000399782.5
BCL2L13
BCL2 like 13
chr9_+_122614738 0.20 ENST00000297913.3
OR1Q1
olfactory receptor family 1 subfamily Q member 1
chr8_+_2045037 0.20 ENST00000262113.9
MYOM2
myomesin 2
chr17_+_42844573 0.20 ENST00000253799.8
ENST00000452774.2
AOC2
amine oxidase copper containing 2
chr13_-_33205997 0.20 ENST00000399365.7
STARD13
StAR related lipid transfer domain containing 13
chr3_+_44874606 0.20 ENST00000296125.9
TGM4
transglutaminase 4
chr20_+_16748358 0.20 ENST00000246081.3
OTOR
otoraplin
chr5_-_147831663 0.20 ENST00000296695.10
SPINK1
serine peptidase inhibitor Kazal type 1
chr2_+_186694007 0.19 ENST00000304698.10
FAM171B
family with sequence similarity 171 member B
chr7_+_151028422 0.19 ENST00000542328.5
ENST00000461373.5
ENST00000297504.10
ENST00000358849.9
ENST00000498578.5
ENST00000477719.5
ENST00000477092.5
ABCB8
ATP binding cassette subfamily B member 8
chr5_+_96743578 0.19 ENST00000325674.11
CAST
calpastatin
chr11_+_114439424 0.19 ENST00000544196.5
ENST00000265881.10
ENST00000539754.5
ENST00000539275.5
REXO2
RNA exonuclease 2
chr8_-_673547 0.19 ENST00000522893.1
ERICH1
glutamate rich 1
chr19_-_55407719 0.19 ENST00000587845.5
ENST00000589978.1
ENST00000264552.14
UBE2S
ubiquitin conjugating enzyme E2 S
chr13_+_45464901 0.19 ENST00000349995.10
COG3
component of oligomeric golgi complex 3
chr6_+_29111560 0.19 ENST00000377169.2
OR2J3
olfactory receptor family 2 subfamily J member 3
chr10_-_67838091 0.19 ENST00000339758.7
DNAJC12
DnaJ heat shock protein family (Hsp40) member C12
chrX_-_120559889 0.18 ENST00000371323.3
CUL4B
cullin 4B
chrX_-_139832235 0.18 ENST00000327569.7
ENST00000361648.6
ATP11C
ATPase phospholipid transporting 11C
chr2_-_150487658 0.18 ENST00000375734.6
ENST00000263895.9
ENST00000454202.5
RND3
Rho family GTPase 3
chr2_+_169069537 0.18 ENST00000428522.5
ENST00000450153.1
ENST00000674881.1
ENST00000421653.5
DHRS9
dehydrogenase/reductase 9
chr6_-_32407123 0.18 ENST00000374993.4
ENST00000544175.2
ENST00000454136.7
ENST00000446536.2
BTNL2
butyrophilin like 2
chr9_-_96383675 0.18 ENST00000375257.2
ENST00000375259.9
ENST00000253270.13
SLC35D2
solute carrier family 35 member D2
chr10_+_4963406 0.18 ENST00000380872.9
ENST00000442997.5
AKR1C1
aldo-keto reductase family 1 member C1
chr15_-_66504832 0.18 ENST00000569438.2
ENST00000569696.5
ENST00000307961.11
RPL4
ribosomal protein L4

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0019858 cytosine metabolic process(GO:0019858)
0.3 2.8 GO:0072564 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.3 0.8 GO:0060128 regulation of calcium-independent cell-cell adhesion(GO:0051040) corticotropin hormone secreting cell differentiation(GO:0060128)
0.3 1.3 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.3 1.8 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.2 1.7 GO:0097338 response to clozapine(GO:0097338)
0.2 1.2 GO:0090131 glomerular mesangial cell development(GO:0072144) mesenchyme migration(GO:0090131)
0.2 1.9 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.2 1.2 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.1 0.6 GO:0070982 L-asparagine biosynthetic process(GO:0070981) L-asparagine metabolic process(GO:0070982)
0.1 0.4 GO:1904440 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.1 0.5 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 0.4 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.1 0.6 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.1 0.4 GO:0006532 aspartate biosynthetic process(GO:0006532)
0.1 0.4 GO:0036071 N-glycan fucosylation(GO:0036071)
0.1 0.7 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 0.5 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.1 0.8 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.1 0.9 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 0.4 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.1 1.1 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 1.4 GO:1903764 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 0.8 GO:0030822 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822)
0.1 1.8 GO:0003417 growth plate cartilage development(GO:0003417)
0.1 0.3 GO:0048560 establishment of anatomical structure orientation(GO:0048560)
0.1 1.3 GO:0035878 nail development(GO:0035878)
0.1 0.2 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.1 0.5 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.1 0.4 GO:0080154 regulation of fertilization(GO:0080154)
0.1 0.2 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
0.1 0.3 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.1 0.7 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.1 0.6 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.1 1.3 GO:0061314 Notch signaling involved in heart development(GO:0061314)
0.1 0.2 GO:1903487 regulation of lactation(GO:1903487)
0.1 0.6 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.1 0.5 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.1 0.3 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.1 0.7 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.6 GO:0051026 chiasma assembly(GO:0051026)
0.1 0.4 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 1.4 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 0.2 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 1.0 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.1 GO:0042412 taurine biosynthetic process(GO:0042412)
0.0 0.4 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.1 GO:1901874 negative regulation of post-translational protein modification(GO:1901874)
0.0 0.2 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.0 1.0 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.4 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.5 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.2 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.7 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.1 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.0 0.2 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.2 GO:0032252 secretory granule localization(GO:0032252)
0.0 0.3 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 1.4 GO:0002076 osteoblast development(GO:0002076)
0.0 0.2 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.2 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.2 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.6 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.2 GO:0010710 calcium-independent cell-matrix adhesion(GO:0007161) regulation of collagen catabolic process(GO:0010710)
0.0 0.2 GO:0010751 regulation of nitric oxide mediated signal transduction(GO:0010749) negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.0 0.4 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:1905006 apoptotic process involved in outflow tract morphogenesis(GO:0003275) negative regulation of alkaline phosphatase activity(GO:0010693) positive regulation of catagen(GO:0051795) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256) negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905006)
0.0 0.2 GO:0035624 receptor transactivation(GO:0035624)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.4 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.1 GO:0061317 canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317)
0.0 0.8 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.4 GO:1903690 positive regulation of extracellular matrix disassembly(GO:0090091) negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.2 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.0 0.6 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.1 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.3 GO:0051451 myoblast migration(GO:0051451)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.3 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.3 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.2 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.5 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.5 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.2 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.2 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.1 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.2 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 1.3 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.2 GO:1900864 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0 0.0 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.0 0.3 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:0021553 olfactory nerve development(GO:0021553)
0.0 0.0 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.0 GO:0061580 colon epithelial cell migration(GO:0061580)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.6 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.2 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.1 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.0 0.1 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.4 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.1 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 1.9 GO:0070268 cornification(GO:0070268)
0.0 0.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.0 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.0 0.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.4 GO:0006833 water transport(GO:0006833)
0.0 0.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.4 GO:0071756 dimeric IgA immunoglobulin complex(GO:0071750) secretory dimeric IgA immunoglobulin complex(GO:0071752) IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
0.1 0.7 GO:0097149 centralspindlin complex(GO:0097149)
0.1 0.6 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 0.5 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 2.2 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 1.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.2 GO:0034677 integrin alpha7-beta1 complex(GO:0034677)
0.1 1.4 GO:0035748 myelin sheath abaxonal region(GO:0035748) MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 0.4 GO:1990357 terminal web(GO:1990357)
0.1 0.4 GO:0002081 outer acrosomal membrane(GO:0002081)
0.1 2.7 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.2 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.8 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 0.7 GO:0032433 filopodium tip(GO:0032433)
0.0 0.4 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.4 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.6 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.8 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.6 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.8 GO:0032982 myosin filament(GO:0032982)
0.0 1.4 GO:0001533 cornified envelope(GO:0001533)
0.0 0.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.3 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.2 GO:0036128 CatSper complex(GO:0036128)
0.0 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.3 GO:0034464 BBSome(GO:0034464)
0.0 0.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 1.1 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.1 GO:0032010 phagolysosome(GO:0032010)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.2 GO:0030056 hemidesmosome(GO:0030056)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.8 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.3 1.5 GO:0050436 microfibril binding(GO:0050436)
0.3 1.8 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.2 1.6 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.5 GO:0003883 CTP synthase activity(GO:0003883)
0.1 1.2 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.1 0.4 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.1 0.4 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1 0.4 GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.1 0.6 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.1 0.6 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1 1.5 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.5 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.4 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 1.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 1.2 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.4 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 0.3 GO:0047023 androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
0.1 1.4 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.3 GO:0052596 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.1 0.5 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 0.4 GO:0019862 IgA binding(GO:0019862)
0.1 0.7 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 0.2 GO:0070052 collagen V binding(GO:0070052)
0.1 0.6 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 0.7 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 1.1 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.5 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 1.0 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 1.1 GO:0017166 vinculin binding(GO:0017166)
0.0 0.2 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.3 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 1.8 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.6 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.2 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.7 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.5 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.0 0.2 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.6 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.3 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.5 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.3 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.8 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.6 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.4 GO:0015250 water channel activity(GO:0015250)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 2.5 GO:0005518 collagen binding(GO:0005518)
0.0 1.1 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.2 GO:0030883 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.2 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.2 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.1 GO:0010465 neurotrophin p75 receptor binding(GO:0005166) nerve growth factor receptor activity(GO:0010465)
0.0 0.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.2 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.0 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.0 0.3 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.3 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 1.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.0 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0042301 phosphate ion binding(GO:0042301)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.8 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.8 PID IL1 PATHWAY IL1-mediated signaling events
0.0 2.0 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.7 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.5 PID NOTCH PATHWAY Notch signaling pathway
0.0 3.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.7 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.8 PID BMP PATHWAY BMP receptor signaling
0.0 0.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.2 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 2.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 1.0 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.1 0.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 1.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.2 REACTOME SIGNALING BY ERBB4 Genes involved in Signaling by ERBB4
0.0 2.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.6 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 1.8 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.7 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.2 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 1.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 2.9 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 0.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.5 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.8 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.8 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.1 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.1 REACTOME PI3K AKT ACTIVATION Genes involved in PI3K/AKT activation
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.2 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.5 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.6 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.1 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 1.2 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism