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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for CEBPE_CEBPD

Z-value: 1.12

Motif logo

Transcription factors associated with CEBPE_CEBPD

Gene Symbol Gene ID Gene Info
ENSG00000092067.6 CEBPE
ENSG00000221869.5 CEBPD

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CEBPDhg38_v1_chr8_-_47738153_477381730.844.3e-09Click!
CEBPEhg38_v1_chr14_-_23119248_231192650.328.3e-02Click!

Activity profile of CEBPE_CEBPD motif

Sorted Z-values of CEBPE_CEBPD motif

Network of associatons between targets according to the STRING database.

First level regulatory network of CEBPE_CEBPD

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr2_-_112836702 6.85 ENST00000416750.1
ENST00000263341.7
ENST00000418817.5
interleukin 1 beta
chr2_-_215436061 6.32 ENST00000421182.5
ENST00000432072.6
ENST00000323926.10
ENST00000336916.8
ENST00000357867.8
ENST00000359671.5
ENST00000446046.5
ENST00000354785.11
ENST00000356005.8
ENST00000443816.5
ENST00000426059.1
fibronectin 1
chr1_-_186680411 5.99 ENST00000367468.10
prostaglandin-endoperoxide synthase 2
chr2_-_31414694 5.32 ENST00000379416.4
xanthine dehydrogenase
chr8_-_6877928 5.22 ENST00000297439.4
defensin beta 1
chr9_-_91423819 4.51 ENST00000297689.4
nuclear factor, interleukin 3 regulated
chr20_+_35172046 4.30 ENST00000216968.5
protein C receptor
chr8_+_123182635 3.78 ENST00000276699.10
ENST00000522648.5
family with sequence similarity 83 member A
chr1_+_154405326 3.51 ENST00000368485.8
interleukin 6 receptor
chr19_-_35528221 3.48 ENST00000588674.5
ENST00000452271.7
ENST00000518157.1
suprabasin
chr2_+_113127588 3.14 ENST00000409930.4
interleukin 1 receptor antagonist
chr1_+_154405193 3.01 ENST00000622330.4
ENST00000344086.8
interleukin 6 receptor
chr16_-_84618067 2.93 ENST00000262428.5
coactosin like F-actin binding protein 1
chr16_-_84618041 2.90 ENST00000564057.1
coactosin like F-actin binding protein 1
chr4_-_138242325 2.74 ENST00000280612.9
solute carrier family 7 member 11
chr20_-_54173976 2.51 ENST00000216862.8
cytochrome P450 family 24 subfamily A member 1
chr10_+_17228215 2.36 ENST00000544301.7
vimentin
chr12_-_122703346 2.30 ENST00000328880.6
hydroxycarboxylic acid receptor 2
chr10_-_17617235 2.27 ENST00000466335.1
3-hydroxyacyl-CoA dehydratase 1
chr11_-_18248662 2.26 ENST00000256733.9
serum amyloid A2
chr10_+_75431605 2.24 ENST00000611255.5
leucine rich melanocyte differentiation associated
chr11_+_18266254 2.15 ENST00000532858.5
ENST00000649195.1
ENST00000356524.9
ENST00000405158.2
serum amyloid A1
chr12_-_122716790 2.01 ENST00000528880.3
hydroxycarboxylic acid receptor 3
chr14_+_20469399 2.01 ENST00000361505.10
ENST00000553591.1
purine nucleoside phosphorylase
chr11_-_18248632 1.89 ENST00000524555.3
ENST00000528349.5
ENST00000526900.1
ENST00000529528.5
ENST00000414546.6
SAA2-SAA4 readthrough
serum amyloid A2
chr10_-_17617326 1.76 ENST00000326961.6
ENST00000361271.8
3-hydroxyacyl-CoA dehydratase 1
chr3_+_12351493 1.75 ENST00000683699.1
peroxisome proliferator activated receptor gamma
chr12_+_66189254 1.52 ENST00000457197.2
interleukin 1 receptor associated kinase 3
chr19_-_40465736 1.51 ENST00000263368.9
ENST00000595483.5
biliverdin reductase B
chr19_-_40465760 1.50 ENST00000643519.1
biliverdin reductase B
chr19_-_35501878 1.46 ENST00000593342.5
ENST00000601650.1
ENST00000408915.6
dermokine
chrX_+_139530730 1.46 ENST00000218099.7
coagulation factor IX
chr5_-_140633167 1.45 ENST00000302014.11
CD14 molecule
chr15_-_74203172 1.44 ENST00000616000.4
signaling receptor and transporter of retinol STRA6
chr3_+_12351470 1.39 ENST00000287820.10
peroxisome proliferator activated receptor gamma
chr17_+_2796404 1.28 ENST00000366401.8
ENST00000254695.13
ENST00000542807.1
RAP1 GTPase activating protein 2
chr20_-_22585451 1.24 ENST00000377115.4
forkhead box A2
chr15_+_45635017 1.20 ENST00000260324.12
sulfide quinone oxidoreductase
chr13_+_32031706 1.20 ENST00000542859.6
FRY microtubule binding protein
chr12_+_29223659 1.13 ENST00000182377.8
fatty acyl-CoA reductase 2
chr12_+_29223730 1.13 ENST00000547116.5
fatty acyl-CoA reductase 2
chr14_-_45253402 1.10 ENST00000627697.1
MIS18 binding protein 1
chr19_+_39412650 1.08 ENST00000425673.6
pleckstrin homology and RhoGEF domain containing G2
chr6_-_132734692 1.07 ENST00000509351.5
ENST00000417437.6
ENST00000423615.6
ENST00000427187.6
ENST00000414302.7
ENST00000367927.9
ENST00000450865.2
vanin 3
chr5_+_50667405 1.05 ENST00000505554.5
poly(ADP-ribose) polymerase family member 8
chr4_-_121823843 1.05 ENST00000274026.10
cyclin A2
chr15_+_40594001 1.05 ENST00000346991.9
ENST00000528975.5
kinetochore scaffold 1
chr22_-_28711931 1.04 ENST00000434810.5
ENST00000456369.5
checkpoint kinase 2
chr5_-_147906530 1.03 ENST00000318315.5
ENST00000515291.1
chromosome 5 open reading frame 46
chr14_+_103121457 1.02 ENST00000333007.8
TNF alpha induced protein 2
chr2_-_68467272 1.00 ENST00000377957.4
F-box protein 48
chr14_-_55191534 0.98 ENST00000395425.6
ENST00000247191.7
DLG associated protein 5
chr5_-_140633690 0.98 ENST00000512545.1
ENST00000401743.6
CD14 molecule
chr11_+_62728069 0.97 ENST00000530625.5
tetratricopeptide repeat domain 9C
chr8_-_123541197 0.96 ENST00000517956.5
ENST00000443022.2
F-box protein 32
chr1_-_37634864 0.96 ENST00000356545.7
R-spondin 1
chr3_-_16264891 0.95 ENST00000488423.2
ENST00000383775.4
diphthamide biosynthesis 3
chr9_-_39288138 0.93 ENST00000297668.10
contactin associated protein family member 3
chr1_+_192158448 0.91 ENST00000367460.4
regulator of G protein signaling 18
chr4_-_113761068 0.88 ENST00000342666.9
ENST00000514328.5
ENST00000515496.5
ENST00000508738.5
ENST00000379773.6
calcium/calmodulin dependent protein kinase II delta
chr6_-_30075767 0.88 ENST00000244360.8
ENST00000376751.8
ring finger protein 39
chr19_-_2042066 0.87 ENST00000591588.1
ENST00000591142.5
MAPK interacting serine/threonine kinase 2
chr15_+_39581068 0.86 ENST00000397591.2
ENST00000260356.6
thrombospondin 1
chr15_+_40594241 0.85 ENST00000532056.5
ENST00000527044.5
ENST00000399668.7
kinetochore scaffold 1
chr12_+_66189208 0.84 ENST00000261233.9
interleukin 1 receptor associated kinase 3
chr3_+_130850585 0.80 ENST00000505330.5
ENST00000504381.5
ENST00000507488.6
ATPase secretory pathway Ca2+ transporting 1
chr5_+_96662046 0.78 ENST00000338252.7
ENST00000508830.5
calpastatin
chr22_-_28712136 0.77 ENST00000464581.6
checkpoint kinase 2
chr11_-_106077401 0.76 ENST00000526793.5
kelch repeat and BTB domain containing 3
chr11_+_62728465 0.76 ENST00000316461.9
tetratricopeptide repeat domain 9C
chr4_-_113761927 0.74 ENST00000296402.9
calcium/calmodulin dependent protein kinase II delta
chr2_+_68467544 0.69 ENST00000303795.9
aprataxin and PNKP like factor
chr18_-_31760864 0.69 ENST00000269205.7
ENST00000672005.1
solute carrier family 25 member 52
chr10_+_30434176 0.69 ENST00000263056.6
ENST00000375322.2
mitogen-activated protein kinase kinase kinase 8
chr19_+_1383891 0.68 ENST00000539480.5
ENST00000313408.11
ENST00000233627.14
ENST00000620479.4
ENST00000414651.3
NADH:ubiquinone oxidoreductase core subunit S7
chr20_+_841238 0.66 ENST00000541082.2
family with sequence similarity 110 member A
chr14_-_45253161 0.66 ENST00000451174.1
ENST00000310806.9
MIS18 binding protein 1
chr5_-_132777344 0.63 ENST00000378706.5
septin 8
chr2_-_61018228 0.63 ENST00000316752.11
pseudouridine synthase 10
chr4_-_113761724 0.62 ENST00000511664.6
calcium/calmodulin dependent protein kinase II delta
chr4_-_113761441 0.62 ENST00000394524.7
calcium/calmodulin dependent protein kinase II delta
chr7_+_43764191 0.61 ENST00000424330.1
biliverdin reductase A
chr4_-_76007501 0.60 ENST00000264888.6
C-X-C motif chemokine ligand 9
chr19_-_48993300 0.60 ENST00000323798.8
ENST00000263276.6
glycogen synthase 1
chr1_-_204213943 0.60 ENST00000308302.4
golgi transport 1A
chrX_-_40647509 0.59 ENST00000378421.1
ENST00000378426.5
ENST00000327877.10
chromosome X open reading frame 38
chr19_-_41439528 0.58 ENST00000301183.15
ENST00000417807.7
ENST00000590641.6
distal membrane arm assembly complex 2
chr3_+_16265160 0.57 ENST00000627468.2
ENST00000605932.5
ENST00000435829.6
ENST00000285083.10
oxidoreductase NAD binding domain containing 1
chr7_-_122304738 0.55 ENST00000442488.7
FEZ family zinc finger 1
chr7_+_90403386 0.55 ENST00000287916.8
ENST00000394604.5
ENST00000496677.6
ENST00000394605.2
ENST00000480135.1
claudin 12
novel transcript
chr17_+_59209867 0.54 ENST00000578922.1
ENST00000300917.10
SMG8 nonsense mediated mRNA decay factor
chr3_-_48088800 0.54 ENST00000423088.5
microtubule associated protein 4
chr1_-_67054100 0.52 ENST00000235345.6
solute carrier family 35 member D1
chr3_+_11272413 0.51 ENST00000446450.6
ENST00000354956.9
ENST00000354449.7
ENST00000419112.5
autophagy related 7
chr8_-_133297092 0.50 ENST00000522890.5
ENST00000675983.1
ENST00000518176.5
ENST00000323851.13
ENST00000522476.5
ENST00000518066.5
ENST00000521544.5
ENST00000674605.1
ENST00000518480.5
ENST00000523892.5
N-myc downstream regulated 1
chr4_+_54229261 0.49 ENST00000508170.5
ENST00000512143.1
ENST00000257290.10
platelet derived growth factor receptor alpha
chr17_-_28854972 0.49 ENST00000583953.6
family with sequence similarity 222 member B
chr15_+_67125707 0.49 ENST00000540846.6
SMAD family member 3
chr16_+_72054477 0.49 ENST00000355906.10
ENST00000570083.5
ENST00000228226.12
ENST00000398131.6
ENST00000569639.5
ENST00000564499.5
ENST00000357763.8
ENST00000613898.1
ENST00000562526.5
ENST00000565574.5
ENST00000568417.6
haptoglobin
chr15_+_58138368 0.49 ENST00000219919.9
ENST00000536493.1
aquaporin 9
chr11_-_106077313 0.48 ENST00000531837.2
ENST00000534815.1
kelch repeat and BTB domain containing 3
chr5_-_132777866 0.48 ENST00000448933.5
septin 8
chr17_-_79839387 0.46 ENST00000448310.1
ENST00000269397.9
chromobox 4
chr19_-_1652576 0.44 ENST00000453954.6
ENST00000395423.7
ENST00000262965.12
ENST00000588136.7
transcription factor 3
chr3_+_16265330 0.44 ENST00000606098.1
oxidoreductase NAD binding domain containing 1
chr14_+_51847145 0.43 ENST00000615906.4
G protein subunit gamma 2
chr17_+_75093287 0.43 ENST00000538213.6
ENST00000584118.1
solute carrier family 16 member 5
chr19_-_41439899 0.43 ENST00000597457.5
ENST00000589970.5
ENST00000595425.5
ENST00000438807.7
ENST00000589102.1
ENST00000221943.14
ENST00000592922.6
distal membrane arm assembly complex 2
chr9_+_107283256 0.42 ENST00000358015.8
RAD23 homolog B, nucleotide excision repair protein
chr20_+_56412112 0.42 ENST00000360314.7
Cas scaffold protein family member 4
chr1_+_81800368 0.42 ENST00000674489.1
ENST00000674442.1
ENST00000674419.1
ENST00000674407.1
ENST00000674168.1
ENST00000674307.1
ENST00000674209.1
ENST00000370715.5
ENST00000370713.5
ENST00000319517.10
ENST00000627151.2
ENST00000370717.6
adhesion G protein-coupled receptor L2
chr8_-_25458389 0.41 ENST00000221200.9
potassium channel tetramerization domain containing 9
chr6_-_99349647 0.41 ENST00000389677.6
failed axon connections homolog, metaxin like GST domain containing
chrX_-_52517213 0.40 ENST00000375616.5
X antigen family member 1B
chr3_+_136930469 0.40 ENST00000469404.1
ENST00000467911.1
NCK adaptor protein 1
chr20_+_4686448 0.40 ENST00000379440.9
ENST00000424424.2
ENST00000457586.2
prion protein
chr1_+_196888014 0.39 ENST00000367416.6
ENST00000608469.6
ENST00000251424.8
ENST00000367418.2
complement factor H related 4
chr19_-_35513641 0.39 ENST00000339686.8
ENST00000447113.6
dermokine
chr1_+_111227610 0.38 ENST00000369744.6
chitinase 3 like 2
chr2_-_24328113 0.37 ENST00000622089.4
intersectin 2
chr1_+_111227699 0.37 ENST00000369748.9
chitinase 3 like 2
chr1_+_196774813 0.37 ENST00000471440.6
ENST00000391985.7
ENST00000617219.1
ENST00000367425.9
complement factor H related 3
chr4_-_184825960 0.36 ENST00000281455.7
acyl-CoA synthetase long chain family member 1
chr4_+_77158252 0.36 ENST00000395640.5
cyclin G2
chr11_-_57324907 0.36 ENST00000358252.8
tankyrase 1 binding protein 1
chr20_+_56412249 0.36 ENST00000679887.1
ENST00000434344.2
Cas scaffold protein family member 4
chr19_+_33373694 0.35 ENST00000284000.9
CCAAT enhancer binding protein gamma
chr4_+_77158418 0.35 ENST00000509972.1
cyclin G2
chr19_+_10718114 0.35 ENST00000408974.8
dynamin 2
chr4_-_184826030 0.35 ENST00000507295.5
ENST00000504900.5
ENST00000454703.6
acyl-CoA synthetase long chain family member 1
chr19_-_15332507 0.35 ENST00000679869.1
ENST00000360016.9
bromodomain containing 4
chr19_-_54189670 0.35 ENST00000391754.5
membrane bound O-acyltransferase domain containing 7
chr7_+_128241272 0.34 ENST00000308868.5
leptin
chr12_-_52680398 0.34 ENST00000252244.3
keratin 1
chr2_-_101308681 0.33 ENST00000295317.4
ring finger protein 149
chr1_-_36464262 0.32 ENST00000373116.6
mitochondrial ribosomal protein S15
chr5_-_132777371 0.32 ENST00000620483.4
septin 8
chrX_+_52495791 0.32 ENST00000375602.2
ENST00000375600.5
X antigen family member 1A
chr17_-_43125300 0.31 ENST00000497488.1
ENST00000354071.7
ENST00000489037.1
ENST00000470026.5
ENST00000644555.1
ENST00000586385.5
ENST00000591534.5
ENST00000591849.5
BRCA1 DNA repair associated
chr19_+_44671452 0.30 ENST00000358777.9
CEA cell adhesion molecule 19
chr5_+_96662314 0.30 ENST00000674702.1
calpastatin
chr7_-_142258027 0.29 ENST00000552471.1
ENST00000547058.6
serine protease 58
chr15_+_81000913 0.29 ENST00000267984.4
talin rod domain containing 1
chr10_-_24706622 0.29 ENST00000680286.1
Rho GTPase activating protein 21
chr1_-_161118024 0.29 ENST00000368010.4
prefoldin subunit 2
chr19_+_10718047 0.29 ENST00000585892.5
ENST00000355667.11
ENST00000389253.9
ENST00000359692.10
dynamin 2
chr11_-_33774347 0.28 ENST00000526785.5
ENST00000534136.5
ENST00000530401.5
ENST00000265651.8
ENST00000448981.6
F-box protein 3
chr7_+_23106267 0.28 ENST00000409689.5
ENST00000410047.1
kelch like family member 7
chr4_-_39977836 0.28 ENST00000303538.13
ENST00000503396.5
PDS5 cohesin associated factor A
chr11_+_33258304 0.28 ENST00000531504.5
ENST00000456517.2
homeodomain interacting protein kinase 3
chr3_-_58214671 0.28 ENST00000460422.1
ENST00000483681.5
deoxyribonuclease 1 like 3
chr7_+_22727147 0.27 ENST00000426291.5
ENST00000401651.5
ENST00000258743.10
ENST00000407492.5
ENST00000401630.7
ENST00000406575.1
interleukin 6
chr6_+_101398788 0.26 ENST00000369138.5
ENST00000413795.5
ENST00000358361.7
glutamate ionotropic receptor kainate type subunit 2
chr20_+_56412393 0.26 ENST00000679529.1
Cas scaffold protein family member 4
chr1_+_209768482 0.26 ENST00000367023.5
TRAF3 interacting protein 3
chr5_-_132777404 0.25 ENST00000296873.11
septin 8
chr20_+_64084995 0.25 ENST00000349451.3
opioid related nociceptin receptor 1
chr19_+_11239602 0.24 ENST00000252453.12
angiopoietin like 8
chr16_+_70646536 0.24 ENST00000288098.6
interleukin 34
chr1_-_47231715 0.23 ENST00000371884.6
TAL bHLH transcription factor 1, erythroid differentiation factor
chr5_+_96662214 0.23 ENST00000395812.6
calpastatin
chr3_-_122514876 0.23 ENST00000493510.1
ENST00000476916.5
ENST00000344337.11
ENST00000465882.5
karyopherin subunit alpha 1
chr14_-_80231052 0.23 ENST00000557010.5
iodothyronine deiodinase 2
chr6_+_31547560 0.23 ENST00000376148.9
ENST00000376145.8
NFKB inhibitor like 1
chr1_-_62319264 0.23 ENST00000354381.3
KN motif and ankyrin repeat domains 4
chr20_-_1619996 0.22 ENST00000381603.7
ENST00000381605.9
ENST00000279477.11
ENST00000568365.1
ENST00000564763.1
signal regulatory protein beta 1
novel protein, SIRPB1-SIRPD readthrough
chr2_-_100417608 0.22 ENST00000264249.8
carbohydrate sulfotransferase 10
chr2_-_208254232 0.22 ENST00000415913.5
ENST00000415282.5
ENST00000446179.5
isocitrate dehydrogenase (NADP(+)) 1
chr3_+_98166696 0.22 ENST00000641450.1
olfactory receptor family 5 subfamily H member 15
chr3_+_141324208 0.22 ENST00000509842.5
zinc finger and BTB domain containing 38
chr19_-_13938371 0.21 ENST00000588872.3
ENST00000339560.10
podocan like 1
chr4_-_112285892 0.21 ENST00000361717.4
TRAF interacting protein with forkhead associated domain
chrX_-_106038721 0.21 ENST00000372563.2
serpin family A member 7
chr1_+_52056255 0.21 ENST00000489308.6
basic transcription factor 3 like 4
chr5_+_96662366 0.21 ENST00000675179.1
ENST00000421689.6
ENST00000674984.1
ENST00000512620.5
calpastatin
chr6_+_1389553 0.21 ENST00000645481.2
forkhead box F2
chr18_+_35041387 0.20 ENST00000538170.6
ENST00000300249.10
ENST00000588910.5
microtubule associated protein RP/EB family member 2
chr22_-_32464440 0.20 ENST00000397450.2
ENST00000397452.5
ENST00000300399.8
BPI fold containing family C
chr1_-_41484680 0.20 ENST00000372587.5
endothelin 2
chr2_-_191014137 0.20 ENST00000673777.1
ENST00000673942.1
ENST00000424722.6
ENST00000392322.7
ENST00000361099.8
ENST00000392323.6
ENST00000673816.1
ENST00000673847.1
ENST00000673952.1
ENST00000540176.6
ENST00000673841.1
signal transducer and activator of transcription 1
chr17_+_7558465 0.20 ENST00000349228.8
TNF superfamily member 13
chr12_+_103930600 0.19 ENST00000680316.1
ENST00000679861.1
heat shock protein 90 beta family member 1
chr12_-_91179517 0.19 ENST00000551354.1
decorin
chr19_+_48445961 0.18 ENST00000253237.10
glutamate rich WD repeat containing 1
chr1_+_161118083 0.18 ENST00000368009.7
ENST00000368007.8
ENST00000392190.9
ENST00000368008.5
nitrilase 1
chr11_-_35360050 0.18 ENST00000644868.1
ENST00000643454.1
ENST00000646080.1
solute carrier family 1 member 2
chr2_+_63842325 0.18 ENST00000445915.6
ENST00000475462.5
UDP-glucose pyrophosphorylase 2
chr10_-_90921079 0.18 ENST00000371697.4
ankyrin repeat domain 1
chr5_+_161850597 0.18 ENST00000634335.1
ENST00000635880.1
gamma-aminobutyric acid type A receptor subunit alpha1
chr17_-_7114648 0.18 ENST00000355035.9
asialoglycoprotein receptor 2
chr17_-_7114813 0.18 ENST00000254850.11
asialoglycoprotein receptor 2
chr10_+_88990531 0.18 ENST00000355740.7
Fas cell surface death receptor
chr3_-_123961399 0.18 ENST00000488653.6
coiled-coil domain containing 14
chr12_+_13044371 0.18 ENST00000197268.13
family with sequence similarity 234 member B
chr9_-_74887720 0.17 ENST00000449912.6
transient receptor potential cation channel subfamily M member 6
chr11_-_59212869 0.17 ENST00000361050.4
macrophage expressed 1
chr5_+_50666917 0.17 ENST00000514342.6
poly(ADP-ribose) polymerase family member 8
chr5_+_50666950 0.17 ENST00000513738.5
ENST00000503665.5
ENST00000514067.6
ENST00000503046.5
poly(ADP-ribose) polymerase family member 8
chr3_+_122183664 0.17 ENST00000639785.2
calcium sensing receptor
chr10_+_88990621 0.16 ENST00000352159.8
Fas cell surface death receptor

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 6.9 GO:0060559 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
2.1 6.3 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
2.0 6.0 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
1.8 5.3 GO:0046110 xanthine metabolic process(GO:0046110)
1.7 6.8 GO:0002384 hepatic immune response(GO:0002384)
1.3 5.2 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.6 2.5 GO:0042369 vitamin D catabolic process(GO:0042369)
0.6 1.8 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.6 1.7 GO:0010933 macrophage tolerance induction(GO:0010931) regulation of macrophage tolerance induction(GO:0010932) positive regulation of macrophage tolerance induction(GO:0010933)
0.5 2.4 GO:0071727 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.5 1.8 GO:1903575 cornified envelope assembly(GO:1903575)
0.5 2.3 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.4 3.1 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.4 3.1 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.4 1.2 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.4 2.3 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.4 1.1 GO:0071373 cellular response to cocaine(GO:0071314) cellular response to luteinizing hormone stimulus(GO:0071373)
0.3 1.2 GO:0070221 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.3 1.2 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.3 2.0 GO:0046102 inosine metabolic process(GO:0046102)
0.3 0.9 GO:0010752 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of cGMP-mediated signaling(GO:0010752)
0.3 3.6 GO:0006787 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.2 0.5 GO:0038086 VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
0.2 1.4 GO:0061143 alveolar primary septum development(GO:0061143)
0.2 0.6 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.2 4.0 GO:0030497 fatty acid elongation(GO:0030497)
0.2 0.3 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
0.2 2.9 GO:1901725 regulation of histone deacetylase activity(GO:1901725)
0.2 0.5 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.2 1.0 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.2 1.5 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.2 2.4 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.1 0.5 GO:0015722 canalicular bile acid transport(GO:0015722)
0.1 0.5 GO:1990535 neuron projection maintenance(GO:1990535)
0.1 0.4 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.1 0.4 GO:0070510 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.1 0.8 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 0.5 GO:1901859 late nucleophagy(GO:0044805) negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859) response to fluoride(GO:1902617)
0.1 0.7 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.1 0.3 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.1 1.9 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 0.3 GO:0051039 histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.1 6.4 GO:0006953 acute-phase response(GO:0006953)
0.1 2.9 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 0.5 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.9 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.5 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 4.0 GO:0050832 defense response to fungus(GO:0050832)
0.1 3.8 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.1 0.7 GO:0034201 adiponectin-activated signaling pathway(GO:0033211) response to oleic acid(GO:0034201)
0.1 1.0 GO:0015939 pantothenate metabolic process(GO:0015939)
0.1 0.2 GO:0060374 basophil differentiation(GO:0030221) mast cell differentiation(GO:0060374)
0.1 1.0 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.2 GO:0006097 glyoxylate cycle(GO:0006097)
0.1 0.4 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 0.1 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.1 0.1 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.1 0.7 GO:0051106 positive regulation of DNA ligation(GO:0051106)
0.1 0.2 GO:0003099 positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.1 0.6 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 1.5 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.1 0.2 GO:0031247 actin rod assembly(GO:0031247)
0.1 1.0 GO:0051601 exocyst localization(GO:0051601)
0.1 0.8 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.5 GO:0036337 Fas signaling pathway(GO:0036337) necroptotic signaling pathway(GO:0097527)
0.1 0.2 GO:0060454 positive regulation of gastric acid secretion(GO:0060454)
0.1 0.5 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.1 GO:0016999 antibiotic metabolic process(GO:0016999)
0.1 0.6 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 1.8 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:0052331 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.0 3.3 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 0.5 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287) positive regulation of spindle checkpoint(GO:0090232)
0.0 0.3 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:0050705 regulation of interleukin-1 alpha secretion(GO:0050705) positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.1 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.4 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.4 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 2.0 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.9 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.3 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.0 0.1 GO:1903610 regulation of calcium-dependent ATPase activity(GO:1903610) negative regulation of calcium-dependent ATPase activity(GO:1903611) regulation of dUTP diphosphatase activity(GO:1903627) positive regulation of dUTP diphosphatase activity(GO:1903629) negative regulation of aminoacyl-tRNA ligase activity(GO:1903631) regulation of leucine-tRNA ligase activity(GO:1903633) negative regulation of leucine-tRNA ligase activity(GO:1903634)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.1 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.0 0.2 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.4 GO:0071380 cellular response to prostaglandin E stimulus(GO:0071380)
0.0 0.1 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0 0.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 3.7 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.3 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.2 GO:0045651 positive regulation of macrophage differentiation(GO:0045651) positive regulation of monocyte differentiation(GO:0045657)
0.0 0.2 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.4 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.0 0.1 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.0 0.2 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.2 GO:0050746 regulation of lipoprotein metabolic process(GO:0050746)
0.0 0.1 GO:1900133 regulation of renin secretion into blood stream(GO:1900133)
0.0 0.4 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 1.0 GO:0002090 regulation of receptor internalization(GO:0002090)
0.0 0.2 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.1 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.0 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.0 0.7 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.0 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.2 GO:0006309 apoptotic DNA fragmentation(GO:0006309)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 6.8 GO:0005896 interleukin-6 receptor complex(GO:0005896)
1.3 5.2 GO:1990742 microvesicle(GO:1990742)
0.6 7.2 GO:0005577 fibrinogen complex(GO:0005577)
0.3 2.4 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.5 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 1.8 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.1 1.1 GO:0001939 female pronucleus(GO:0001939) male pronucleus(GO:0001940)
0.1 4.0 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 0.4 GO:0071942 XPC complex(GO:0071942)
0.1 0.4 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.1 7.9 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.1 2.3 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 0.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 1.0 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 5.7 GO:0005901 caveola(GO:0005901)
0.0 0.3 GO:0016272 prefoldin complex(GO:0016272)
0.0 1.0 GO:0000145 exocyst(GO:0000145)
0.0 7.5 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 0.1 GO:0097179 protease inhibitor complex(GO:0097179)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 3.2 GO:0043195 terminal bouton(GO:0043195)
0.0 0.5 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.5 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.5 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.6 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.9 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 3.7 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 3.0 GO:0016605 PML body(GO:0016605)
0.0 3.6 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 1.9 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 2.6 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.2 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.4 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 1.5 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.7 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.2 GO:0035371 microtubule plus-end(GO:0035371)
0.0 1.9 GO:0000922 spindle pole(GO:0000922)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.5 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
1.7 5.2 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
1.3 4.0 GO:0080023 3R-hydroxyacyl-CoA dehydratase activity(GO:0080023)
1.2 6.0 GO:0050473 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
1.0 3.1 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.9 3.6 GO:0004074 biliverdin reductase activity(GO:0004074)
0.9 5.3 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.5 2.7 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.5 2.5 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.5 2.0 GO:0002060 purine nucleobase binding(GO:0002060)
0.5 2.3 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.4 2.4 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.4 2.4 GO:1990254 keratin filament binding(GO:1990254)
0.4 6.7 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.3 3.1 GO:0050692 DBD domain binding(GO:0050692)
0.3 0.9 GO:0070052 collagen V binding(GO:0070052)
0.3 1.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.3 4.4 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.2 1.2 GO:0016672 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672)
0.2 0.5 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.2 0.5 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.2 1.5 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 0.4 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 2.9 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 5.4 GO:0042056 chemoattractant activity(GO:0042056)
0.1 0.6 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.5 GO:1903135 cupric ion binding(GO:1903135)
0.1 0.4 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.1 0.5 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.5 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.1 0.5 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.2 GO:0051990 isocitrate dehydrogenase (NADP+) activity(GO:0004450) (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.1 4.9 GO:0016504 peptidase activator activity(GO:0016504)
0.1 0.4 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.3 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 0.8 GO:0004568 chitinase activity(GO:0004568)
0.1 0.2 GO:0001626 nociceptin receptor activity(GO:0001626)
0.1 0.2 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.6 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 0.5 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 0.4 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.9 GO:0010857 calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.0 0.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.4 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.1 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 5.1 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.2 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.2 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.6 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 1.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.7 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.7 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0004341 gluconolactonase activity(GO:0004341)
0.0 0.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.7 GO:0048038 quinone binding(GO:0048038)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.5 GO:0032183 SUMO binding(GO:0032183)
0.0 0.1 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.2 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 1.1 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.0 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.5 GO:0043015 gamma-tubulin binding(GO:0043015)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.8 ST STAT3 PATHWAY STAT3 Pathway
0.2 6.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2 7.2 PID IL27 PATHWAY IL27-mediated signaling events
0.2 6.0 PID S1P S1P1 PATHWAY S1P1 pathway
0.1 4.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 3.0 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 3.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 1.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 2.3 PID ATM PATHWAY ATM pathway
0.0 0.7 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 2.4 PID AURORA B PATHWAY Aurora B signaling
0.0 1.8 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.4 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.7 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.6 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.5 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.9 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.5 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.4 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 1.1 PID FOXO PATHWAY FoxO family signaling
0.0 0.5 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.2 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 7.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.4 7.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.2 6.4 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.2 2.4 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.2 5.1 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.2 9.2 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 3.7 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.8 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 2.1 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.1 0.7 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 1.5 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 2.9 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 2.5 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 1.8 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 2.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 2.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 1.1 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 3.0 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 1.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.5 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.6 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 3.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.7 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 1.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.6 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.4 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 4.2 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.7 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.0 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones