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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for CUUUGGU

Z-value: 0.59

Motif logo

miRNA associated with seed CUUUGGU

NamemiRBASE accession
MIMAT0000441

Activity profile of CUUUGGU motif

Sorted Z-values of CUUUGGU motif

Network of associatons between targets according to the STRING database.

First level regulatory network of CUUUGGU

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr7_-_41703062 1.62 ENST00000242208.5
inhibin subunit beta A
chr2_-_207166818 1.62 ENST00000423015.5
Kruppel like factor 7
chr3_-_74521140 1.30 ENST00000263665.6
contactin 3
chr11_+_70078291 1.30 ENST00000355303.9
anoctamin 1
chr2_-_1744442 1.25 ENST00000433670.5
ENST00000425171.1
ENST00000252804.9
peroxidasin
chr21_-_43427131 1.19 ENST00000270162.8
salt inducible kinase 1
chr7_-_23470469 1.18 ENST00000258729.8
insulin like growth factor 2 mRNA binding protein 3
chr12_+_65824475 1.15 ENST00000403681.7
high mobility group AT-hook 2
chr12_-_89352487 1.13 ENST00000548755.1
ENST00000279488.8
dual specificity phosphatase 6
chr15_-_41972504 0.91 ENST00000220325.9
EH domain containing 4
chr11_-_128522264 0.90 ENST00000531611.5
ETS proto-oncogene 1, transcription factor
chr2_+_9961165 0.88 ENST00000405379.6
grainyhead like transcription factor 1
chr1_-_154970735 0.87 ENST00000368445.9
ENST00000448116.7
ENST00000368449.8
SHC adaptor protein 1
chr17_-_43022350 0.87 ENST00000587173.5
ENST00000355653.8
vesicle amine transport 1
chr5_-_128538230 0.84 ENST00000262464.9
fibrillin 2
chr6_+_106098933 0.84 ENST00000369089.3
PR/SET domain 1
chr3_+_47282930 0.82 ENST00000232766.6
ENST00000437353.5
kelch like family member 18
chr9_+_128340474 0.81 ENST00000300456.5
solute carrier family 27 member 4
chr18_-_23662868 0.80 ENST00000586087.1
ENST00000592179.6
ankyrin repeat domain 29
chr3_-_98901656 0.79 ENST00000326840.11
discoidin, CUB and LCCL domain containing 2
chr1_+_89633086 0.76 ENST00000370454.9
leucine rich repeat containing 8 VRAC subunit C
chr2_+_64454506 0.76 ENST00000409537.2
galectin like
chr2_+_48314637 0.72 ENST00000413569.5
ENST00000340553.8
forkhead box N2
chr16_+_8720706 0.72 ENST00000425191.6
ENST00000569156.5
4-aminobutyrate aminotransferase
chrX_-_46759055 0.70 ENST00000328306.4
ENST00000616978.5
solute carrier family 9 member A7
chr8_+_28701487 0.69 ENST00000220562.9
exostosin like glycosyltransferase 3
chr15_+_74541200 0.67 ENST00000622429.1
ENST00000346246.10
AT-rich interaction domain 3B
chr17_+_75721451 0.66 ENST00000200181.8
integrin subunit beta 4
chr11_+_60914139 0.66 ENST00000227525.8
transmembrane protein 109
chr1_-_6261053 0.64 ENST00000377893.3
G protein-coupled receptor 153
chr9_-_69672341 0.63 ENST00000265381.7
amyloid beta precursor protein binding family A member 1
chr1_-_6393339 0.62 ENST00000608083.5
acyl-CoA thioesterase 7
chr5_+_136028979 0.60 ENST00000442011.7
transforming growth factor beta induced
chr10_-_33334625 0.60 ENST00000374875.5
ENST00000374822.8
ENST00000374867.7
neuropilin 1
chr15_-_55917129 0.57 ENST00000338963.6
ENST00000508342.5
NEDD4 E3 ubiquitin protein ligase
chr3_+_150408314 0.56 ENST00000361875.7
TSC22 domain family member 2
chr10_+_97584347 0.56 ENST00000370649.3
ENST00000370646.9
novel protein
4-hydroxy-2-oxoglutarate aldolase 1
chr2_+_74834113 0.55 ENST00000290573.7
hexokinase 2
chr1_+_37474572 0.55 ENST00000373087.7
zinc finger CCCH-type containing 12A
chr20_+_37346128 0.54 ENST00000373578.7
SRC proto-oncogene, non-receptor tyrosine kinase
chr5_-_77492309 0.54 ENST00000296679.9
ENST00000507029.5
WD repeat domain 41
chr2_-_101387453 0.54 ENST00000324768.6
cellular repressor of E1A stimulated genes 2
chr1_+_154405193 0.52 ENST00000622330.4
ENST00000344086.8
interleukin 6 receptor
chr12_-_109477293 0.52 ENST00000228495.11
ENST00000542858.1
ENST00000542262.5
potassium channel tetramerization domain containing 10
chr19_+_1941118 0.51 ENST00000255641.13
casein kinase 1 gamma 2
chr5_-_132227808 0.51 ENST00000401867.5
ENST00000379086.5
ENST00000379100.7
ENST00000418055.5
ENST00000453286.5
ENST00000360568.8
ENST00000379104.7
ENST00000166534.8
prolyl 4-hydroxylase subunit alpha 2
chr13_+_110307276 0.51 ENST00000360467.7
ENST00000650540.1
collagen type IV alpha 2 chain
chr2_-_234497035 0.50 ENST00000390645.2
ENST00000339728.6
ADP ribosylation factor like GTPase 4C
chr1_-_27490045 0.50 ENST00000536657.1
WASP family member 2
chr16_-_79600698 0.49 ENST00000393350.1
MAF bZIP transcription factor
chr4_-_81214960 0.49 ENST00000395578.3
ENST00000628926.1
protein kinase cGMP-dependent 2
chr6_-_42451910 0.49 ENST00000372922.8
ENST00000541110.5
transcriptional regulating factor 1
chr22_+_37906275 0.48 ENST00000215957.10
ENST00000445494.6
ENST00000680578.1
ENST00000424008.2
MICAL like 1
chr7_-_99144053 0.47 ENST00000361125.1
ENST00000361368.7
SMAD specific E3 ubiquitin protein ligase 1
chr7_-_24980148 0.47 ENST00000313367.7
oxysterol binding protein like 3
chr1_-_208244375 0.46 ENST00000367033.4
plexin A2
chr9_-_35732122 0.45 ENST00000314888.10
talin 1
chr22_-_36387949 0.45 ENST00000216181.11
myosin heavy chain 9
chr1_+_24745396 0.44 ENST00000374379.9
chloride intracellular channel 4
chr5_-_150155828 0.43 ENST00000261799.9
platelet derived growth factor receptor beta
chr6_-_48111132 0.43 ENST00000398738.3
ENST00000679966.1
ENST00000339488.9
patched domain containing 4
chr12_+_56128217 0.42 ENST00000267113.4
ENST00000394048.10
extended synaptotagmin 1
chr15_-_72320149 0.42 ENST00000287202.10
CUGBP Elav-like family member 6
chr1_-_25906411 0.42 ENST00000455785.7
stathmin 1
chr19_+_40717091 0.42 ENST00000263370.3
inositol-trisphosphate 3-kinase C
chr19_-_14518383 0.41 ENST00000254322.3
ENST00000595139.2
DnaJ heat shock protein family (Hsp40) member B1
chrX_-_110318062 0.41 ENST00000372059.6
ENST00000262844.10
AMMECR nuclear protein 1
chr9_-_120877167 0.41 ENST00000373896.8
ENST00000312189.10
PHD finger protein 19
chr10_+_100997040 0.41 ENST00000370223.7
leucine zipper tumor suppressor 2
chr3_+_155079663 0.40 ENST00000460393.6
membrane metalloendopeptidase
chr4_+_17810945 0.40 ENST00000251496.7
non-SMC condensin I complex subunit G
chr14_-_52791597 0.40 ENST00000216410.8
ENST00000557604.1
glucosamine-phosphate N-acetyltransferase 1
chr6_+_150865665 0.40 ENST00000611279.4
ENST00000367321.8
ENST00000367307.8
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
chr5_-_64768619 0.39 ENST00000513458.9
SREK1 interacting protein 1
chr1_+_7771263 0.39 ENST00000054666.11
vesicle associated membrane protein 3
chr21_-_14383125 0.39 ENST00000285667.4
heat shock protein family A (Hsp70) member 13
chr9_-_112333603 0.39 ENST00000450374.1
ENST00000374257.6
ENST00000374255.6
ENST00000334318.10
polypyrimidine tract binding protein 3
chr5_+_83471736 0.39 ENST00000265077.8
versican
chr22_-_41621014 0.39 ENST00000263256.7
desumoylating isopeptidase 1
chr7_+_28412511 0.38 ENST00000357727.7
cAMP responsive element binding protein 5
chr22_-_18024513 0.38 ENST00000441493.7
microtubule associated monooxygenase, calponin and LIM domain containing 3
chr14_-_34462223 0.38 ENST00000298130.5
serine palmitoyltransferase small subunit A
chr15_+_81000913 0.38 ENST00000267984.4
talin rod domain containing 1
chr2_-_55419565 0.38 ENST00000647341.1
ENST00000647401.1
ENST00000336838.10
ENST00000621814.4
ENST00000644033.1
ENST00000645477.1
ENST00000647517.1
coiled-coil domain containing 88A
chr1_+_10032832 0.38 ENST00000253251.12
ENST00000672724.1
ENST00000343090.11
ubiquitination factor E4B
chr15_+_90868580 0.38 ENST00000268171.8
furin, paired basic amino acid cleaving enzyme
chr8_+_42896883 0.38 ENST00000307602.9
hook microtubule tethering protein 3
chr13_-_23375431 0.37 ENST00000683270.1
ENST00000684163.1
ENST00000402364.1
ENST00000683367.1
sacsin molecular chaperone
chr20_+_18588040 0.37 ENST00000377452.4
D-aminoacyl-tRNA deacylase 1
chr12_-_113471851 0.37 ENST00000261731.4
LIM homeobox 5
chr13_+_97434154 0.36 ENST00000245304.5
RAP2A, member of RAS oncogene family
chr6_+_35342535 0.36 ENST00000360694.8
ENST00000418635.6
ENST00000448077.6
peroxisome proliferator activated receptor delta
chr14_+_102592611 0.36 ENST00000262241.7
REST corepressor 1
chr3_-_123884290 0.36 ENST00000346322.9
ENST00000360772.7
ENST00000360304.8
myosin light chain kinase
chr20_-_14337602 0.36 ENST00000378053.3
ENST00000341420.5
fibronectin leucine rich transmembrane protein 3
chr19_-_39833615 0.35 ENST00000593685.5
ENST00000600611.5
dual specificity tyrosine phosphorylation regulated kinase 1B
chrX_+_16719595 0.35 ENST00000380155.4
synapse associated protein 1
chr12_+_113358542 0.35 ENST00000545182.6
ENST00000280800.5
phospholipase B domain containing 2
chr5_-_147782518 0.35 ENST00000507386.5
janus kinase and microtubule interacting protein 2
chr10_+_123666355 0.34 ENST00000284674.2
G protein-coupled receptor 26
chr3_-_185825029 0.34 ENST00000382199.7
insulin like growth factor 2 mRNA binding protein 2
chr17_-_51120855 0.34 ENST00000618113.4
ENST00000357122.8
ENST00000262013.12
sperm associated antigen 9
chr3_+_172040554 0.34 ENST00000336824.8
ENST00000423424.5
fibronectin type III domain containing 3B
chr4_+_86934976 0.34 ENST00000507468.5
ENST00000395146.9
AF4/FMR2 family member 1
chr11_+_35943981 0.33 ENST00000528989.5
ENST00000524419.5
ENST00000315571.6
low density lipoprotein receptor class A domain containing 3
chr19_+_7903843 0.33 ENST00000397981.7
ENST00000397979.4
ENST00000397983.7
mitogen-activated protein kinase kinase 7
chr1_-_179229671 0.33 ENST00000502732.6
ENST00000392043.4
ABL proto-oncogene 2, non-receptor tyrosine kinase
chr11_-_78341876 0.33 ENST00000340149.6
GRB2 associated binding protein 2
chr13_-_33285682 0.33 ENST00000336934.10
StAR related lipid transfer domain containing 13
chr19_+_7830188 0.33 ENST00000270530.8
ecotropic viral integration site 5 like
chr15_-_41332487 0.33 ENST00000560640.1
ENST00000220514.8
Opa interacting protein 5
chr13_-_76886397 0.32 ENST00000377474.4
potassium channel tetramerization domain containing 12
chr8_-_28386417 0.32 ENST00000521185.5
ENST00000520290.5
ENST00000344423.10
zinc finger protein 395
chr14_+_51651858 0.32 ENST00000395718.6
FERM domain containing 6
chr11_+_119206298 0.32 ENST00000634586.1
ENST00000634840.1
ENST00000264033.6
ENST00000637974.1
Cbl proto-oncogene
chr11_+_122655712 0.32 ENST00000284273.6
ubiquitin associated and SH3 domain containing B
chr5_-_141618957 0.32 ENST00000389054.8
diaphanous related formin 1
chr19_+_39125769 0.31 ENST00000602004.1
ENST00000599470.5
ENST00000321944.8
ENST00000593480.5
ENST00000358301.7
ENST00000593690.5
ENST00000599386.5
p21 (RAC1) activated kinase 4
chr9_-_120793377 0.31 ENST00000684001.1
ENST00000684405.1
ENST00000608872.6
F-box and WD repeat domain containing 2
chr9_+_113150991 0.31 ENST00000259392.8
solute carrier family 31 member 2
chrX_+_69504320 0.31 ENST00000252338.5
family with sequence similarity 155 member B
chr1_-_27155118 0.31 ENST00000263980.8
solute carrier family 9 member A1
chr13_-_21459226 0.31 ENST00000320220.13
zinc finger DHHC-type palmitoyltransferase 20
chr22_-_35840218 0.31 ENST00000414461.6
ENST00000416721.6
ENST00000449924.6
ENST00000262829.11
ENST00000397305.3
RNA binding fox-1 homolog 2
chr17_+_74213537 0.31 ENST00000269346.9
tweety family member 2
chr15_+_58771280 0.31 ENST00000559228.6
ENST00000450403.3
MINDY lysine 48 deubiquitinase 2
chr12_+_27332849 0.30 ENST00000544915.5
ENST00000395901.6
ENST00000546179.5
aryl hydrocarbon receptor nuclear translocator like 2
chr17_+_12665882 0.30 ENST00000425538.6
myocardin
chr17_-_81166160 0.30 ENST00000326724.9
apoptosis associated tyrosine kinase
chr14_-_76812804 0.29 ENST00000556298.1
ENST00000251089.8
angel homolog 1
chr21_+_31873010 0.29 ENST00000270112.7
hormonally up-regulated Neu-associated kinase
chr20_-_38165261 0.29 ENST00000361475.7
transglutaminase 2
chr11_-_13463168 0.29 ENST00000526841.1
ENST00000278174.10
ENST00000529708.5
ENST00000528120.5
BTB domain containing 10
chr2_+_11534039 0.29 ENST00000381486.7
growth regulating estrogen receptor binding 1
chr8_+_38231484 0.28 ENST00000533100.5
ENST00000397166.7
ENST00000528358.5
ENST00000529642.1
ENST00000532222.5
ENST00000520272.6
DDHD domain containing 2
chrX_+_9786420 0.28 ENST00000380913.8
shroom family member 2
chr6_+_159969070 0.28 ENST00000356956.6
insulin like growth factor 2 receptor
chr7_+_157138912 0.28 ENST00000611269.4
ENST00000348165.10
ubiquitin protein ligase E3C
chrX_+_28587411 0.28 ENST00000378993.6
interleukin 1 receptor accessory protein like 1
chr5_-_50441244 0.28 ENST00000303221.10
embigin
chr2_-_118847638 0.28 ENST00000295206.7
engrailed homeobox 1
chr2_-_20225123 0.28 ENST00000254351.9
syndecan 1
chr1_+_93345893 0.27 ENST00000370272.9
ENST00000370267.1
down-regulator of transcription 1
chr11_+_64359142 0.27 ENST00000528057.5
ENST00000334205.9
ribosomal protein S6 kinase A4
chrX_-_132218124 0.27 ENST00000342983.6
RAP2C, member of RAS oncogene family
chr16_+_29812230 0.27 ENST00000300797.7
ENST00000637403.1
ENST00000572820.2
ENST00000637064.1
ENST00000636246.1
proline rich transmembrane protein 2
chr22_-_29553691 0.27 ENST00000490103.6
ENST00000397873.6
THO complex 5
chr10_-_15168667 0.27 ENST00000378165.9
N-myristoyltransferase 2
chr16_-_80804581 0.27 ENST00000570137.7
chromodomain Y like 2
chr6_+_31158518 0.27 ENST00000376255.4
ENST00000376257.8
transcription factor 19
chr5_+_34656288 0.27 ENST00000265109.8
retinoic acid induced 14
chr11_-_118176576 0.27 ENST00000278947.6
sodium voltage-gated channel beta subunit 2
chr2_+_6917404 0.27 ENST00000320892.11
ring finger protein 144A
chr18_+_54828406 0.27 ENST00000262094.10
RAB27B, member RAS oncogene family
chr8_+_22367259 0.27 ENST00000520644.1
ENST00000359741.10
ENST00000381237.6
ENST00000240095.10
solute carrier family 39 member 14
chr8_-_143815649 0.26 ENST00000356994.7
scribble planar cell polarity protein
chr13_-_29595670 0.26 ENST00000380752.10
solute carrier family 7 member 1
chr6_-_35921079 0.26 ENST00000507909.1
ENST00000373825.7
SRSF protein kinase 1
chr1_-_115841116 0.26 ENST00000320238.3
nescient helix-loop-helix 2
chr2_+_118088432 0.26 ENST00000245787.9
insulin induced gene 2
chr13_+_113297217 0.25 ENST00000332556.5
lysosomal associated membrane protein 1
chr10_-_102502669 0.25 ENST00000487599.1
actin related protein 1A
chr16_+_68737284 0.25 ENST00000261769.10
ENST00000422392.6
cadherin 1
chr3_-_138834752 0.25 ENST00000477593.5
ENST00000483968.5
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
chr18_+_33578213 0.24 ENST00000681521.1
ENST00000269197.12
ASXL transcriptional regulator 3
chr1_+_25543598 0.24 ENST00000374338.5
low density lipoprotein receptor adaptor protein 1
chr1_-_75611109 0.24 ENST00000370859.7
solute carrier family 44 member 5
chr5_-_78294656 0.24 ENST00000519295.5
ENST00000255194.11
adaptor related protein complex 3 subunit beta 1
chr9_-_38069220 0.24 ENST00000377707.4
SH2 domain containing adaptor protein B
chr7_+_44044663 0.24 ENST00000456905.5
ENST00000440166.5
ENST00000452943.5
ENST00000448521.6
ENST00000468694.5
ENST00000494774.5
drebrin like
chr13_-_39603123 0.24 ENST00000379589.4
LHFPL tetraspan subfamily member 6
chr17_-_7394514 0.24 ENST00000571802.1
ENST00000619711.5
ENST00000576201.5
ENST00000573213.1
ENST00000324822.15
phospholipid scramblase 3
chr9_-_23821275 0.23 ENST00000380110.8
ELAV like RNA binding protein 2
chr13_-_98977975 0.23 ENST00000376460.5
dedicator of cytokinesis 9
chr17_-_7251691 0.23 ENST00000574322.6
CTD nuclear envelope phosphatase 1
chr9_+_74497308 0.23 ENST00000376896.8
RAR related orphan receptor B
chr3_+_111859180 0.23 ENST00000412622.5
ENST00000431670.7
pleckstrin homology like domain family B member 2
chr5_-_83720813 0.23 ENST00000515590.1
ENST00000274341.9
hyaluronan and proteoglycan link protein 1
chr1_+_65147514 0.23 ENST00000545314.5
adenylate kinase 4
chr2_-_27263034 0.23 ENST00000233535.9
solute carrier family 30 member 3
chr19_-_17688326 0.23 ENST00000552293.5
ENST00000551649.5
ENST00000519716.7
ENST00000550896.1
unc-13 homolog A
chr1_+_116909869 0.22 ENST00000393203.3
prostaglandin F2 receptor inhibitor
chr1_+_154325512 0.22 ENST00000368489.6
ENST00000368487.7
ATPase phospholipid transporting 8B2
chr15_+_40382926 0.22 ENST00000608100.5
ENST00000557920.1
kinetochore localized astrin (SPAG5) binding protein
chr6_-_34696733 0.22 ENST00000374023.8
inflammation and lipid regulator with UBA-like and NBR1-like domains
chr16_+_55656249 0.22 ENST00000219833.13
ENST00000574918.2
solute carrier family 6 member 2
chr3_+_197749855 0.22 ENST00000241502.9
forty-two-three domain containing 1
chr2_-_171160833 0.22 ENST00000360843.7
ENST00000431350.7
tousled like kinase 1
chr2_-_130181542 0.21 ENST00000441135.1
ENST00000680679.1
ENST00000680401.1
ENST00000351288.10
ENST00000680298.1
ENST00000431183.6
sphingomyelin phosphodiesterase 4
chr7_-_158829519 0.21 ENST00000251527.10
ENST00000652148.1
extended synaptotagmin 2
chr14_+_52552830 0.21 ENST00000321662.11
G protein-coupled receptor 137C
chr13_-_75482151 0.21 ENST00000377636.8
TBC1 domain family member 4
chr17_-_44503369 0.21 ENST00000585614.1
ENST00000591680.6
G-patch domain containing 8
chr9_-_34589701 0.21 ENST00000351266.8
ciliary neurotrophic factor receptor
chr3_-_120450981 0.21 ENST00000424703.6
ENST00000469005.1
ENST00000295633.8
follistatin like 1
chr16_+_397183 0.21 ENST00000620944.4
ENST00000621774.4
ENST00000219479.7
NME/NM23 nucleoside diphosphate kinase 4
chr1_+_6613722 0.21 ENST00000377648.5
PHD finger protein 13
chr22_-_45240859 0.21 ENST00000336156.10
KIAA0930
chr9_+_93096204 0.21 ENST00000375464.7
caspase recruitment domain family member 19
chr3_-_180036918 0.21 ENST00000465751.5
ENST00000467460.6
ENST00000472994.5
peroxisomal biogenesis factor 5 like

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.3 1.1 GO:0003131 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.3 0.8 GO:1990654 regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
0.3 0.8 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.2 1.2 GO:0010868 negative regulation of triglyceride biosynthetic process(GO:0010868)
0.2 1.1 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.2 0.6 GO:0051821 negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010768) transmission of virus(GO:0019089) dissemination or transmission of symbiont from host(GO:0044007) dissemination or transmission of organism from other organism involved in symbiotic interaction(GO:0051821)
0.2 0.7 GO:1904450 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.2 1.0 GO:0060978 angiogenesis involved in coronary vascular morphogenesis(GO:0060978)
0.2 1.3 GO:0015705 iodide transport(GO:0015705)
0.2 0.6 GO:1900535 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.1 0.6 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.1 0.5 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.6 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.1 0.6 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.1 0.9 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.1 0.5 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.1 1.0 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.3 GO:1900222 negative regulation of beta-amyloid clearance(GO:1900222)
0.1 0.5 GO:1904637 negative regulation by host of viral genome replication(GO:0044828) response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.1 0.5 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.1 0.3 GO:1903281 regulation of the force of heart contraction by cardiac conduction(GO:0086092) positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.1 0.4 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.1 0.1 GO:1903433 regulation of constitutive secretory pathway(GO:1903433)
0.1 0.4 GO:0090472 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.1 1.0 GO:0030578 PML body organization(GO:0030578)
0.1 0.2 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.9 GO:0002934 desmosome organization(GO:0002934)
0.1 0.2 GO:0015917 aminophospholipid transport(GO:0015917)
0.1 0.4 GO:1900756 protein processing in phagocytic vesicle(GO:1900756) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
0.1 0.3 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.1 0.3 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.1 0.4 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.1 0.4 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.1 0.3 GO:0048627 myoblast development(GO:0048627)
0.1 0.1 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
0.1 0.3 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.1 0.4 GO:0006041 glucosamine metabolic process(GO:0006041)
0.1 0.6 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.1 0.3 GO:0061743 motor learning(GO:0061743)
0.1 0.4 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 0.2 GO:1901355 response to rapamycin(GO:1901355)
0.1 0.4 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.3 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.3 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 0.3 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.1 0.3 GO:0003383 apical constriction(GO:0003383)
0.1 0.2 GO:0036451 cap mRNA methylation(GO:0036451)
0.1 0.3 GO:0016080 synaptic vesicle targeting(GO:0016080) protein localization to adherens junction(GO:0071896)
0.1 0.2 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.1 0.6 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.1 0.3 GO:1903826 arginine transmembrane transport(GO:1903826)
0.1 0.2 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.1 0.2 GO:0048867 stem cell fate determination(GO:0048867)
0.1 0.4 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.2 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.4 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.4 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.8 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.1 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 0.1 GO:0042946 glucoside transport(GO:0042946)
0.0 0.7 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.0 0.1 GO:0051695 actin filament uncapping(GO:0051695)
0.0 0.3 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.1 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.2 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.4 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.2 GO:1990167 protein K6-linked deubiquitination(GO:0044313) protein K27-linked deubiquitination(GO:1990167)
0.0 0.7 GO:0035878 nail development(GO:0035878)
0.0 0.2 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 2.0 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.5 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0044691 tooth eruption(GO:0044691)
0.0 0.4 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.2 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.0 0.4 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.4 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.1 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.3 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:0061386 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 1.2 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.1 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.0 0.2 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 0.3 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 0.6 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.0 GO:0071335 submandibular salivary gland formation(GO:0060661) hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.0 0.3 GO:0046684 response to pyrethroid(GO:0046684)
0.0 0.4 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.0 0.2 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 0.1 GO:0003420 regulation of growth plate cartilage chondrocyte proliferation(GO:0003420) histone H3-R2 methylation(GO:0034970)
0.0 0.2 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.2 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.3 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.4 GO:0060973 cell migration involved in heart development(GO:0060973)
0.0 0.4 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.3 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.3 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.0 0.3 GO:0003360 brainstem development(GO:0003360)
0.0 0.2 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.0 0.2 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.0 0.1 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.2 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.2 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.5 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.2 GO:0071680 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 0.4 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.1 GO:0071895 odontoblast differentiation(GO:0071895)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.2 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.4 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.1 GO:0071922 establishment of sister chromatid cohesion(GO:0034085) regulation of chromosome condensation(GO:0060623) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.6 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.2 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
0.0 0.1 GO:0030472 mitotic spindle organization in nucleus(GO:0030472)
0.0 0.4 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.6 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.4 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.3 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.3 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.3 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.1 GO:0043000 negative regulation of anion channel activity(GO:0010360) Golgi to plasma membrane CFTR protein transport(GO:0043000)
0.0 0.3 GO:0015871 choline transport(GO:0015871)
0.0 0.3 GO:1903874 ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.0 0.3 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.0 0.1 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.0 0.1 GO:1904073 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.0 0.9 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.2 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.0 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.2 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.2 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.1 GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010)
0.0 0.2 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.1 GO:0097466 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.0 0.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.1 GO:0009305 protein biotinylation(GO:0009305) histone biotinylation(GO:0071110)
0.0 0.6 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.0 0.7 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.1 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379) renal water absorption(GO:0070295)
0.0 0.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.2 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.0 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686) negative regulation of glucagon secretion(GO:0070093)
0.0 0.3 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.1 GO:0097369 sodium ion import(GO:0097369)
0.0 0.0 GO:0090365 regulation of mRNA modification(GO:0090365)
0.0 0.1 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.2 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.1 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.0 0.1 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.1 GO:0044266 angiotensin catabolic process in blood(GO:0002005) multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266)
0.0 0.3 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.2 GO:0060613 fat pad development(GO:0060613)
0.0 0.3 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.0 0.2 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.0 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408)
0.0 0.1 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.1 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.5 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.0 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.0 0.2 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.2 GO:0015874 norepinephrine transport(GO:0015874)
0.0 0.2 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.1 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.0 0.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.5 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.3 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.3 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.3 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.5 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.0 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
0.0 0.3 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.1 GO:0015866 ADP transport(GO:0015866)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.2 0.9 GO:0070435 Shc-EGFR complex(GO:0070435)
0.2 0.7 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.1 1.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.7 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110)
0.1 0.4 GO:0097513 myosin II filament(GO:0097513)
0.1 1.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.4 GO:0070695 FHF complex(GO:0070695)
0.1 0.5 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.5 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.5 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 0.6 GO:0016600 flotillin complex(GO:0016600)
0.1 0.4 GO:0000796 condensin complex(GO:0000796)
0.0 0.2 GO:1990075 periciliary membrane compartment(GO:1990075)
0.0 0.2 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 1.0 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 3.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.3 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.2 GO:0035363 histone locus body(GO:0035363)
0.0 0.1 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.3 GO:0002177 manchette(GO:0002177)
0.0 0.1 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.2 GO:0044305 calyx of Held(GO:0044305)
0.0 0.7 GO:0032433 filopodium tip(GO:0032433)
0.0 0.4 GO:0070852 cell body fiber(GO:0070852)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.7 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.3 GO:0032010 phagolysosome(GO:0032010)
0.0 0.1 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.0 0.8 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.3 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.5 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.4 GO:0045180 basal cortex(GO:0045180)
0.0 1.2 GO:0002102 podosome(GO:0002102)
0.0 1.9 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.0 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.2 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.3 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 0.2 GO:0030681 multimeric ribonuclease P complex(GO:0030681)
0.0 0.0 GO:0042565 RNA nuclear export complex(GO:0042565)
0.0 0.2 GO:0061202 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0044301 climbing fiber(GO:0044301)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.3 1.1 GO:0035501 MH1 domain binding(GO:0035501)
0.2 1.2 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.2 1.6 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 0.7 GO:0003867 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.2 0.5 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.1 0.4 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.7 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.1 0.9 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 1.0 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 0.3 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.1 0.6 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 0.4 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 0.5 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.4 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.1 0.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.5 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.1 1.0 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 0.6 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.1 0.6 GO:0050815 phosphoserine binding(GO:0050815) phosphothreonine binding(GO:0050816)
0.1 1.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.6 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.3 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.1 0.5 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 1.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.7 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.2 GO:0005334 norepinephrine:sodium symporter activity(GO:0005334)
0.1 0.5 GO:0071253 connexin binding(GO:0071253)
0.1 0.2 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.1 0.3 GO:0070004 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.0 0.1 GO:0042947 glucoside transmembrane transporter activity(GO:0042947)
0.0 0.1 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.8 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.8 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.4 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.2 GO:0030226 apolipoprotein receptor activity(GO:0030226)
0.0 0.1 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.0 0.6 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.2 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.2 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 2.0 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.2 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0070644 9-cis retinoic acid receptor activity(GO:0004886) retinoic acid-responsive element binding(GO:0044323) vitamin D response element binding(GO:0070644)
0.0 0.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.3 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.1 GO:0004488 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.0 0.3 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.3 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.3 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.1 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.0 0.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.1 GO:0001601 peptide YY receptor activity(GO:0001601)
0.0 0.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.7 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.3 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078) mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.5 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.3 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.2 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.5 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.3 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.2 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 1.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.7 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.8 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.5 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.2 GO:0018812 3-hydroxyacyl-CoA dehydratase activity(GO:0018812)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0018271 biotin-[acetyl-CoA-carboxylase] ligase activity(GO:0004077) biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity(GO:0004078) biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity(GO:0004079) biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity(GO:0004080) biotin-protein ligase activity(GO:0018271)
0.0 0.5 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.0 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.4 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.6 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.5 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.4 GO:0071949 FAD binding(GO:0071949)
0.0 0.0 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.0 0.0 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.1 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.4 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.0 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.0 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 ST STAT3 PATHWAY STAT3 Pathway
0.0 1.7 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.6 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.7 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.0 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.0 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.0 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.8 PID REELIN PATHWAY Reelin signaling pathway
0.0 1.0 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 1.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.2 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.8 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.4 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.7 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.8 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.3 PID IL3 PATHWAY IL3-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 0.9 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.1 0.9 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.5 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.3 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.0 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.0 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.2 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.3 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.6 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.1 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.5 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.1 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.3 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.2 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.2 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.1 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation