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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for CUX2

Z-value: 0.73

Motif logo

Transcription factors associated with CUX2

Gene Symbol Gene ID Gene Info
ENSG00000111249.14 CUX2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CUX2hg38_v1_chr12_+_111034136_1110341730.086.7e-01Click!

Activity profile of CUX2 motif

Sorted Z-values of CUX2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of CUX2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_-_109075944 2.23 ENST00000338366.6
TATA-box binding protein associated factor 13
chr7_-_23470469 2.17 ENST00000258729.8
insulin like growth factor 2 mRNA binding protein 3
chr2_+_95025700 2.11 ENST00000309988.9
ENST00000353004.7
ENST00000354078.7
ENST00000349807.3
mal, T cell differentiation protein
chr1_+_31576485 1.82 ENST00000457433.6
ENST00000271064.12
tubulointerstitial nephritis antigen like 1
chr12_-_10826358 1.79 ENST00000240619.2
taste 2 receptor member 10
chr1_-_153041111 1.72 ENST00000360379.4
small proline rich protein 2D
chr21_-_26843012 1.67 ENST00000517777.6
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr8_-_61646807 1.66 ENST00000522919.5
aspartate beta-hydroxylase
chr2_-_215393126 1.65 ENST00000456923.5
fibronectin 1
chr21_-_26843063 1.58 ENST00000678221.1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr15_-_59689283 1.56 ENST00000607373.6
ENST00000612191.4
ENST00000267859.8
BCL2 interacting protein 2
chr8_-_90082871 1.52 ENST00000265431.7
calbindin 1
chr9_+_102995308 1.45 ENST00000612124.4
ENST00000374798.8
ENST00000487798.5
cylicin 2
chr3_+_100635598 1.42 ENST00000475887.1
adhesion G protein-coupled receptor G7
chr2_+_101839815 1.42 ENST00000421882.5
mitogen-activated protein kinase kinase kinase kinase 4
chr6_+_151239951 1.35 ENST00000402676.7
A-kinase anchoring protein 12
chr1_+_171185293 1.33 ENST00000209929.10
flavin containing dimethylaniline monoxygenase 2
chr2_-_191151568 1.29 ENST00000358470.8
ENST00000432798.1
ENST00000450994.1
signal transducer and activator of transcription 4
chr7_+_80602200 1.27 ENST00000534394.5
CD36 molecule
chr7_+_80602150 1.24 ENST00000309881.11
CD36 molecule
chr16_+_11345429 1.17 ENST00000576027.1
ENST00000312499.6
ENST00000648619.1
RecQ mediated genome instability 2
chr8_+_53851786 1.16 ENST00000297313.8
ENST00000344277.10
regulator of G protein signaling 20
chr11_-_105139750 1.14 ENST00000530950.2
caspase recruitment domain family member 18
chr9_+_122371036 1.10 ENST00000619306.5
ENST00000426608.6
ENST00000223423.8
prostaglandin-endoperoxide synthase 1
chr19_+_47713412 1.07 ENST00000538399.1
ENST00000263277.8
EH domain containing 2
chr19_+_44905785 1.07 ENST00000446996.5
ENST00000252486.9
ENST00000434152.5
apolipoprotein E
chr6_-_131000722 1.06 ENST00000528282.5
erythrocyte membrane protein band 4.1 like 2
chrX_-_108439472 1.05 ENST00000372216.8
collagen type IV alpha 6 chain
chr14_-_80959484 1.00 ENST00000555529.5
ENST00000556042.5
ENST00000556981.5
centrosomal protein 128
chr22_+_44752552 0.92 ENST00000389774.6
ENST00000356099.11
ENST00000396119.6
ENST00000336963.8
ENST00000412433.5
Rho GTPase activating protein 8
chr19_+_41797147 0.89 ENST00000596544.1
CEA cell adhesion molecule 3
chr10_-_119536533 0.88 ENST00000392865.5
regulator of G protein signaling 10
chr11_+_5389377 0.88 ENST00000328611.5
olfactory receptor family 51 subfamily M member 1
chr2_+_102337148 0.85 ENST00000311734.6
ENST00000409584.5
interleukin 1 receptor like 1
chr19_-_4535221 0.83 ENST00000381848.7
ENST00000586133.1
perilipin 5
chr11_+_62856149 0.82 ENST00000535296.5
solute carrier family 3 member 2
chr6_-_130956371 0.82 ENST00000639623.1
ENST00000525193.5
ENST00000527659.5
erythrocyte membrane protein band 4.1 like 2
chr14_-_63728027 0.80 ENST00000247225.7
sphingosine-1-phosphate phosphatase 1
chr9_+_122371014 0.80 ENST00000362012.7
prostaglandin-endoperoxide synthase 1
chr15_+_41286011 0.79 ENST00000661438.1
novel protein
chr6_+_121435595 0.79 ENST00000649003.1
ENST00000282561.4
gap junction protein alpha 1
chr22_+_18527802 0.78 ENST00000612978.5
transmembrane protein 191B
chr19_-_7058640 0.78 ENST00000333843.8
methyl-CpG binding domain protein 3 like 3
chr19_+_926001 0.76 ENST00000263620.8
AT-rich interaction domain 3A
chr17_-_41369807 0.73 ENST00000251646.8
keratin 33B
chr15_+_40382715 0.72 ENST00000416151.6
ENST00000249776.12
kinetochore localized astrin (SPAG5) binding protein
chr19_+_41376560 0.72 ENST00000436170.6
transmembrane protein 91
chr3_+_123067016 0.70 ENST00000316218.12
protein disulfide isomerase family A member 5
chr5_+_163460650 0.69 ENST00000358715.3
hyaluronan mediated motility receptor
chr19_+_41376499 0.69 ENST00000392002.7
transmembrane protein 91
chr15_+_40382764 0.69 ENST00000448395.6
kinetochore localized astrin (SPAG5) binding protein
chr19_+_45499797 0.68 ENST00000401593.5
ENST00000396736.2
protein phosphatase, Mg2+/Mn2+ dependent 1N (putative)
chr6_+_26272923 0.66 ENST00000377733.4
H2B clustered histone 10
chr5_+_163460623 0.66 ENST00000393915.9
ENST00000432118.6
hyaluronan mediated motility receptor
chr6_-_27146841 0.66 ENST00000356950.2
H2B clustered histone 12
chr5_-_11588842 0.65 ENST00000503622.5
catenin delta 2
chr7_+_80646305 0.65 ENST00000426978.5
ENST00000432207.5
CD36 molecule
chr16_-_88663065 0.64 ENST00000301012.8
ENST00000569177.5
mevalonate diphosphate decarboxylase
chr6_-_49636832 0.64 ENST00000371175.10
ENST00000646272.1
ENST00000646939.1
ENST00000618248.3
ENST00000229810.9
ENST00000646963.1
Rh associated glycoprotein
chr5_-_11589019 0.64 ENST00000511377.5
catenin delta 2
chr3_-_48089203 0.64 ENST00000468075.2
ENST00000360240.10
microtubule associated protein 4
chrX_+_54920796 0.64 ENST00000442098.5
ENST00000430420.5
ENST00000453081.5
ENST00000319167.12
ENST00000622017.4
ENST00000375022.8
ENST00000399736.5
ENST00000440072.5
ENST00000173898.12
ENST00000431115.5
ENST00000440759.5
ENST00000375041.6
trophinin
chr6_+_106086316 0.63 ENST00000369091.6
ENST00000369096.9
PR/SET domain 1
chr19_-_14778552 0.63 ENST00000315576.8
adhesion G protein-coupled receptor E2
chr19_+_7030578 0.63 ENST00000329753.5
methyl-CpG binding domain protein 3 like 5
chr18_+_63777773 0.62 ENST00000447428.5
ENST00000546027.5
serpin family B member 7
chr22_-_26565362 0.61 ENST00000398110.6
tyrosylprotein sulfotransferase 2
chr1_+_115029823 0.60 ENST00000256592.3
thyroid stimulating hormone subunit beta
chr19_+_14941489 0.60 ENST00000248072.3
olfactory receptor family 7 subfamily C member 2
chr21_-_43075831 0.60 ENST00000398158.5
ENST00000398165.8
cystathionine beta-synthase
chr19_+_11089446 0.60 ENST00000557933.5
ENST00000455727.6
ENST00000535915.5
ENST00000545707.5
ENST00000558518.6
ENST00000558013.5
low density lipoprotein receptor
chr4_+_108650585 0.60 ENST00000613215.4
ENST00000361564.9
oligosaccharyltransferase complex non-catalytic subunit
chr18_+_63587297 0.59 ENST00000269489.9
serpin family B member 13
chr19_-_42528380 0.58 ENST00000403461.5
ENST00000352591.9
ENST00000358394.7
ENST00000403444.7
ENST00000161559.11
ENST00000599389.1
CEA cell adhesion molecule 1
chr11_+_62856072 0.58 ENST00000377890.6
ENST00000681467.1
ENST00000538084.2
ENST00000681569.1
ENST00000377891.6
ENST00000680725.1
ENST00000377889.6
solute carrier family 3 member 2
chr6_-_27912396 0.56 ENST00000303324.4
olfactory receptor family 2 subfamily B member 2
chr9_+_72577369 0.56 ENST00000651183.1
transmembrane channel like 1
chr19_+_41376692 0.56 ENST00000447302.6
ENST00000544232.5
ENST00000542945.5
ENST00000540732.3
transmembrane protein 91
novel protein
chr19_-_48740573 0.56 ENST00000222145.9
Ras interacting protein 1
chr3_+_26694499 0.56 ENST00000456208.2
leucine rich repeat containing 3B
chr11_+_89924064 0.55 ENST00000623787.3
tripartite motif containing 49D2
chr21_-_43076362 0.55 ENST00000359624.7
ENST00000352178.9
cystathionine beta-synthase
chrX_-_66033664 0.55 ENST00000427538.5
V-set and immunoglobulin domain containing 4
chr2_-_88947820 0.55 ENST00000496168.1
immunoglobulin kappa variable 1-5
chr2_-_186849164 0.55 ENST00000295131.3
zinc finger SWIM-type containing 2
chr6_-_26285526 0.54 ENST00000377727.2
H4 clustered histone 8
chr4_+_70721953 0.53 ENST00000381006.8
ENST00000226328.8
RUN and FYVE domain containing 3
chr22_-_50085331 0.53 ENST00000395876.6
modulator of VRAC current 1
chr1_-_53838276 0.53 ENST00000371429.4
NDC1 transmembrane nucleoporin
chr11_+_94768331 0.53 ENST00000317829.12
ENST00000433060.3
angiomotin like 1
chr7_-_36724543 0.53 ENST00000612871.4
acyloxyacyl hydrolase
chr11_-_48983826 0.52 ENST00000649162.1
tripartite motif-containing 51G, pseudogene
chr3_+_130931893 0.52 ENST00000504612.5
ATPase secretory pathway Ca2+ transporting 1
chr4_+_186266183 0.52 ENST00000403665.7
ENST00000492972.6
ENST00000264692.8
coagulation factor XI
chr7_-_36724457 0.51 ENST00000617537.5
ENST00000435386.1
acyloxyacyl hydrolase
chr6_+_31137646 0.51 ENST00000547221.1
psoriasis susceptibility 1 candidate 1
chr1_+_155209213 0.51 ENST00000609421.1
metaxin 1
chr22_-_50085414 0.51 ENST00000311597.10
modulator of VRAC current 1
chrX_-_47629845 0.51 ENST00000469388.1
ENST00000396992.8
ENST00000377005.6
complement factor properdin
chr9_+_107306459 0.50 ENST00000457811.1
RAD23 homolog B, nucleotide excision repair protein
chr6_+_29100609 0.50 ENST00000377171.3
olfactory receptor family 2 subfamily J member 1
chr3_+_44874606 0.50 ENST00000296125.9
transglutaminase 4
chr4_-_142305935 0.50 ENST00000511838.5
inositol polyphosphate-4-phosphatase type II B
chr14_+_24070837 0.49 ENST00000537691.5
ENST00000397016.6
ENST00000560356.5
ENST00000558450.5
copine 6
chr19_-_58353482 0.49 ENST00000263100.8
alpha-1-B glycoprotein
chr11_-_19060706 0.49 ENST00000329773.3
MAS related GPR family member X2
chr7_+_142750657 0.49 ENST00000492062.1
serine protease 1
chr19_-_52171643 0.49 ENST00000597065.1
zinc finger protein 836
chrX_+_86714623 0.49 ENST00000484479.1
dachshund family transcription factor 2
chr3_+_136957948 0.49 ENST00000329582.9
interleukin 20 receptor subunit beta
chr8_+_81280527 0.49 ENST00000297258.11
fatty acid binding protein 5
chr8_-_143953845 0.48 ENST00000354958.6
plectin
chr1_+_86993009 0.48 ENST00000370548.3
novel protein
chr4_+_108650644 0.47 ENST00000512478.2
oligosaccharyltransferase complex non-catalytic subunit
chr8_-_123025750 0.47 ENST00000523036.1
derlin 1
chr3_-_197226351 0.47 ENST00000656428.1
discs large MAGUK scaffold protein 1
chr4_-_69961007 0.46 ENST00000353151.3
casein beta
chr7_-_99679987 0.46 ENST00000222982.8
ENST00000439761.3
ENST00000339843.6
cytochrome P450 family 3 subfamily A member 5
chr2_-_171434763 0.46 ENST00000442778.5
ENST00000453846.5
ENST00000612742.5
methyltransferase like 8
chr8_+_18391276 0.46 ENST00000286479.4
ENST00000520116.1
N-acetyltransferase 2
chr16_-_18562074 0.45 ENST00000543392.5
ENST00000622306.5
ENST00000381474.7
ENST00000621364.4
ENST00000330537.10
NODAL modulator 2
chr5_+_168529299 0.45 ENST00000338333.5
fibrillarin like 1
chr1_+_56854764 0.45 ENST00000361249.4
complement C8 alpha chain
chr19_-_42427379 0.45 ENST00000244289.9
lipase E, hormone sensitive type
chr16_+_22505845 0.45 ENST00000356156.7
nuclear pore complex interacting protein family member B5
chr4_-_151227881 0.44 ENST00000652233.1
ENST00000514152.5
SH3 domain containing 19
chr4_-_159035226 0.44 ENST00000434826.3
chromosome 4 open reading frame 45
chr8_-_123025627 0.44 ENST00000519018.5
derlin 1
chr20_-_22585451 0.44 ENST00000377115.4
forkhead box A2
chr1_+_196819731 0.43 ENST00000320493.10
ENST00000367424.4
complement factor H related 1
chr3_+_197950176 0.42 ENST00000448864.6
ENST00000647248.2
ribosomal protein L35a
chr3_+_102099244 0.42 ENST00000491959.5
zona pellucida like domain containing 1
chr17_-_82840010 0.42 ENST00000269394.4
ENST00000572562.1
zinc finger protein 750
chr3_+_159839847 0.42 ENST00000445224.6
schwannomin interacting protein 1
chr3_+_35641421 0.41 ENST00000449196.5
cAMP regulated phosphoprotein 21
chr4_+_73409340 0.41 ENST00000511370.1
albumin
chr11_-_55936400 0.40 ENST00000301532.3
olfactory receptor family 5 subfamily I member 1
chr5_-_16742221 0.40 ENST00000505695.5
myosin X
chr7_+_151956379 0.40 ENST00000431418.6
polypeptide N-acetylgalactosaminyltransferase like 5
chr8_+_12104389 0.39 ENST00000400085.7
zinc finger protein 705D
chr3_+_191329020 0.39 ENST00000392456.4
coiled-coil domain containing 50
chr21_+_38272291 0.39 ENST00000438657.5
potassium inwardly rectifying channel subfamily J member 15
chr17_-_66229380 0.39 ENST00000205948.11
apolipoprotein H
chr4_+_176319942 0.39 ENST00000503362.2
signal peptidase complex subunit 3
chr12_-_64390727 0.39 ENST00000543942.7
chromosome 12 open reading frame 56
chr18_-_5396265 0.38 ENST00000579951.2
erythrocyte membrane protein band 4.1 like 3
chr9_-_21187671 0.38 ENST00000421715.2
interferon alpha 4
chr1_-_75932392 0.38 ENST00000284142.7
ankyrin repeat and SOCS box containing 17
chr5_-_156963222 0.38 ENST00000407087.4
ENST00000274532.7
T cell immunoglobulin and mucin domain containing 4
chr21_+_38272410 0.38 ENST00000398934.5
ENST00000398930.5
potassium inwardly rectifying channel subfamily J member 15
chr16_-_69754913 0.38 ENST00000268802.10
NIN1 (RPN12) binding protein 1 homolog
chr10_+_49637400 0.37 ENST00000640822.1
choline O-acetyltransferase
chr15_-_65133780 0.37 ENST00000204549.9
programmed cell death 7
chr13_+_57140918 0.37 ENST00000377931.1
ENST00000614894.4
proline rich 20A
proline rich 20C
chr12_-_10453330 0.37 ENST00000347831.9
ENST00000359151.8
killer cell lectin like receptor C1
chr11_+_57597563 0.37 ENST00000619430.2
ENST00000457869.1
ENST00000340687.10
ENST00000278407.9
ENST00000378323.8
ENST00000378324.6
ENST00000403558.1
serpin family G member 1
chr11_+_56176618 0.37 ENST00000312298.1
olfactory receptor family 5 subfamily J member 2
chr12_-_51324652 0.36 ENST00000544402.5
bridging integrator 2
chr5_+_58491427 0.36 ENST00000396776.6
ENST00000502276.6
ENST00000511930.2
GRB2 binding adaptor protein, transmembrane
chr3_-_173141227 0.36 ENST00000351008.4
spermatogenesis associated 16
chr12_+_80099535 0.36 ENST00000646859.1
ENST00000547103.7
otogelin like
chr5_+_58491451 0.36 ENST00000513924.2
ENST00000515443.2
GRB2 binding adaptor protein, transmembrane
chr1_+_196774813 0.36 ENST00000471440.6
ENST00000391985.7
ENST00000617219.1
ENST00000367425.9
complement factor H related 3
chr14_+_21990357 0.36 ENST00000390444.1
T cell receptor alpha variable 16
chr2_+_33436304 0.35 ENST00000402538.7
RAS guanyl releasing protein 3
chr19_-_4400418 0.35 ENST00000598564.5
ENST00000417295.6
ENST00000269886.7
SH3 domain containing GRB2 like 1, endophilin A2
chr8_-_109974688 0.35 ENST00000297404.1
potassium voltage-gated channel modifier subfamily V member 1
chr19_+_3224701 0.35 ENST00000541430.6
CUGBP Elav-like family member 5
chr1_+_77779618 0.35 ENST00000370791.7
ENST00000443751.3
ENST00000645756.1
ENST00000643390.1
ENST00000642959.1
mitoguardin 1
chr6_-_138218491 0.35 ENST00000527246.3
prostate and breast cancer overexpressed 1
chr17_+_58238426 0.35 ENST00000421678.6
ENST00000262290.9
ENST00000543544.5
lactoperoxidase
chr12_-_10909562 0.34 ENST00000390677.2
taste 2 receptor member 13
chr4_+_15339818 0.34 ENST00000397700.6
ENST00000295297.4
C1q and TNF related 7
chr5_+_127649018 0.34 ENST00000379445.7
cortexin 3
chr12_+_112906777 0.34 ENST00000452357.7
ENST00000445409.7
2'-5'-oligoadenylate synthetase 1
chr11_+_65890627 0.33 ENST00000312579.4
coiled-coil domain containing 85B
chr1_-_247536440 0.33 ENST00000366487.4
ENST00000641802.1
olfactory receptor family 2 subfamily C member 3
chr6_-_116829037 0.33 ENST00000368549.7
ENST00000530250.1
ENST00000310357.8
G protein-coupled receptor class C group 6 member A
chr3_+_158110052 0.33 ENST00000295930.7
ENST00000471994.5
ENST00000482822.3
ENST00000476899.6
ENST00000683899.1
ENST00000684604.1
ENST00000682164.1
ENST00000464171.5
ENST00000611884.5
ENST00000312179.10
ENST00000475278.6
arginine and serine rich coiled-coil 1
chr14_-_91732059 0.33 ENST00000553329.5
ENST00000256343.8
cation channel sperm associated auxiliary subunit beta
chr9_+_122370523 0.33 ENST00000643810.1
ENST00000540753.6
prostaglandin-endoperoxide synthase 1
chr4_-_68951763 0.32 ENST00000251566.9
UDP glucuronosyltransferase family 2 member A3
chr9_+_94084458 0.32 ENST00000620992.5
ENST00000288976.3
protein tyrosine phosphatase domain containing 1
chr12_+_75334655 0.32 ENST00000378695.9
GLIPR1 like 1
chr20_-_58228653 0.32 ENST00000457363.1
ankyrin repeat domain 60
chr2_+_113406368 0.32 ENST00000453673.3
immunoglobulin kappa variable 1/OR2-108 (non-functional)
chr7_+_57450171 0.32 ENST00000420713.2
zinc finger protein 716
chr4_-_89835617 0.31 ENST00000611107.1
ENST00000345009.8
ENST00000505199.5
ENST00000502987.5
synuclein alpha
chr6_-_75284820 0.31 ENST00000475111.6
transmembrane protein 30A
chr7_+_151956440 0.31 ENST00000392800.7
ENST00000616416.4
polypeptide N-acetylgalactosaminyltransferase like 5
chrY_-_24047969 0.31 ENST00000306882.4
ENST00000382407.1
chromodomain Y-linked 1B
chr6_-_26216673 0.31 ENST00000541790.3
H2B clustered histone 8
chr3_+_8501807 0.31 ENST00000426878.2
ENST00000397386.7
ENST00000415597.5
ENST00000157600.8
LIM and cysteine rich domains 1
chr4_+_69931066 0.31 ENST00000246891.9
casein alpha s1
chr11_+_44095710 0.31 ENST00000358681.8
ENST00000343631.4
ENST00000682711.1
exostosin glycosyltransferase 2
chr11_+_122838492 0.31 ENST00000227348.9
cytotoxic and regulatory T cell molecule
chr11_+_7088991 0.31 ENST00000306904.7
RBMX like 2
chr6_-_29087313 0.31 ENST00000377173.4
olfactory receptor family 2 subfamily B member 3
chr2_+_100974849 0.31 ENST00000450763.1
neuronal PAS domain protein 2
chr12_+_8989612 0.30 ENST00000266551.8
killer cell lectin like receptor G1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.4 1.9 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.4 1.1 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.4 3.2 GO:0070543 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.2 1.4 GO:0060356 leucine import(GO:0060356)
0.2 0.6 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.2 0.6 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
0.2 0.6 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.2 0.8 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.2 0.6 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.2 1.2 GO:0046439 cysteine biosynthetic process from serine(GO:0006535) cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) homocysteine catabolic process(GO:0043418) L-cysteine metabolic process(GO:0046439)
0.2 1.5 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.2 3.3 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.2 0.5 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.2 0.5 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.2 1.3 GO:0070995 NADPH oxidation(GO:0070995)
0.2 0.8 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.2 0.5 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.2 2.1 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.2 0.6 GO:0015670 carbon dioxide transport(GO:0015670)
0.2 0.8 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.2 0.5 GO:1903487 regulation of lactation(GO:1903487)
0.2 0.9 GO:0019060 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.2 0.5 GO:0034963 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.1 0.6 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 0.4 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.1 0.4 GO:0019836 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.1 1.1 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.1 0.4 GO:1903762 positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
0.1 0.6 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.4 GO:0001868 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.1 1.3 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.9 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 0.5 GO:0009822 alkaloid catabolic process(GO:0009822)
0.1 2.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.4 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.1 0.6 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.7 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 0.3 GO:0099557 trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission(GO:0099557)
0.1 1.9 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 1.1 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.1 0.5 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 0.9 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.1 0.6 GO:0097283 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.1 0.2 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 1.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.4 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.3 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 0.3 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.1 1.4 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.1 1.0 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.1 0.3 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 2.7 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.2 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 0.2 GO:0060720 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.1 0.2 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
0.1 0.2 GO:0036245 cellular response to menadione(GO:0036245)
0.1 0.3 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.1 1.3 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1 0.2 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.2 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 0.3 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.2 GO:0009720 detection of hormone stimulus(GO:0009720)
0.1 0.2 GO:0036451 cap mRNA methylation(GO:0036451)
0.1 0.3 GO:0051620 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1 0.7 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.5 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.0 0.2 GO:1903803 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0 0.2 GO:0003069 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.0 1.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 1.2 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.4 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.1 GO:0098759 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.0 0.1 GO:0071931 positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931)
0.0 0.2 GO:1990523 bone regeneration(GO:1990523)
0.0 1.4 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.5 GO:0002860 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.3 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.0 0.1 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.0 0.3 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:1902573 positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.0 0.4 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.5 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.0 0.2 GO:0043382 positive regulation of memory T cell differentiation(GO:0043382)
0.0 0.4 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.2 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.4 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.3 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.1 GO:0071284 copper ion export(GO:0060003) cellular response to lead ion(GO:0071284)
0.0 0.8 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.3 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.1 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.2 GO:0051343 positive regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051343)
0.0 0.3 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 1.8 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.4 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.6 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 4.9 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.3 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.2 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.2 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.2 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.2 GO:0070858 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.0 0.2 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.3 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.2 GO:0032439 endosome localization(GO:0032439) positive regulation of pinocytosis(GO:0048549)
0.0 0.5 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.2 GO:0086043 bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
0.0 2.1 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 1.9 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0 0.1 GO:1905244 apolipoprotein A-I-mediated signaling pathway(GO:0038027) skeletal muscle satellite cell migration(GO:1902766) regulation of modification of synaptic structure(GO:1905244)
0.0 0.1 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.0 0.3 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.5 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.5 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.1 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.2 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.4 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.2 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.2 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.0 2.2 GO:0042035 regulation of cytokine biosynthetic process(GO:0042035)
0.0 0.2 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.1 GO:0036369 transcription factor catabolic process(GO:0036369)
0.0 0.2 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.1 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
0.0 0.5 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.0 GO:0002339 B cell selection(GO:0002339)
0.0 0.1 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.2 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 1.5 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.7 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.3 GO:0043383 negative T cell selection(GO:0043383)
0.0 0.0 GO:2000143 negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0 0.3 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 1.1 GO:0018279 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.4 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.4 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.0 1.1 GO:0002279 mast cell activation involved in immune response(GO:0002279) mast cell degranulation(GO:0043303)
0.0 0.1 GO:0009597 detection of virus(GO:0009597)
0.0 1.4 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.5 GO:0033189 response to vitamin A(GO:0033189)
0.0 0.9 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.0 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.0 0.3 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.0 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.0 0.5 GO:0000732 strand displacement(GO:0000732)
0.0 0.5 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.9 GO:0006968 cellular defense response(GO:0006968)
0.0 0.0 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.0 0.5 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.0 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.0 GO:1990764 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.0 0.5 GO:0031648 protein destabilization(GO:0031648)
0.0 0.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.3 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.1 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.2 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 1.3 GO:0051149 positive regulation of muscle cell differentiation(GO:0051149)
0.0 0.5 GO:0035329 hippo signaling(GO:0035329)
0.0 0.5 GO:1901998 toxin transport(GO:1901998)
0.0 0.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0033150 cytoskeletal calyx(GO:0033150)
0.3 1.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.2 0.6 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.2 1.9 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.2 0.9 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.1 1.6 GO:0005577 fibrinogen complex(GO:0005577)
0.1 1.0 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 1.9 GO:0008091 spectrin(GO:0008091)
0.1 0.5 GO:0071942 XPC complex(GO:0071942)
0.1 0.3 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.1 3.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.4 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 0.4 GO:0002079 inner acrosomal membrane(GO:0002079)
0.1 0.3 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.3 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.1 1.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.5 GO:0005816 spindle pole body(GO:0005816)
0.1 0.4 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.5 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.3 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 1.7 GO:0035371 microtubule plus-end(GO:0035371)
0.0 2.2 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.1 GO:0097679 other organism cytoplasm(GO:0097679)
0.0 0.5 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.4 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.3 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0034515 proteasome storage granule(GO:0034515)
0.0 0.4 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.8 GO:0005916 fascia adherens(GO:0005916)
0.0 1.8 GO:0001533 cornified envelope(GO:0001533)
0.0 0.6 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.3 GO:0036128 CatSper complex(GO:0036128)
0.0 0.7 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.0 0.5 GO:0030056 hemidesmosome(GO:0030056)
0.0 3.5 GO:0005604 basement membrane(GO:0005604)
0.0 0.5 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.2 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.2 GO:1990630 IRE1-RACK1-PP2A complex(GO:1990630)
0.0 0.2 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.6 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.1 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 2.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 2.7 GO:0005901 caveola(GO:0005901)
0.0 0.4 GO:0032433 filopodium tip(GO:0032433)
0.0 0.5 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.4 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.5 GO:0071437 invadopodium(GO:0071437)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.3 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.2 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 1.5 GO:0043195 terminal bouton(GO:0043195)
0.0 0.3 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.5 GO:0042629 mast cell granule(GO:0042629)
0.0 0.2 GO:0043194 axon initial segment(GO:0043194)
0.0 0.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.2 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 1.2 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 1.6 GO:0043204 perikaryon(GO:0043204)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.1 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.9 GO:0043679 axon terminus(GO:0043679)
0.0 0.2 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 1.7 GO:0035579 specific granule membrane(GO:0035579)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.9 GO:0030315 T-tubule(GO:0030315)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.4 2.2 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.4 3.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.3 1.0 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.3 1.2 GO:0050421 oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
0.3 0.9 GO:0002113 interleukin-33 binding(GO:0002113)
0.3 1.5 GO:0005499 vitamin D binding(GO:0005499)
0.2 1.1 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.2 0.6 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.2 1.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 1.4 GO:0004111 creatine kinase activity(GO:0004111)
0.2 1.9 GO:0042731 PH domain binding(GO:0042731)
0.2 0.5 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.2 0.5 GO:0036009 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.1 0.4 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 0.7 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 0.8 GO:0035473 lipase binding(GO:0035473)
0.1 0.8 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 2.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.7 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 1.1 GO:0089720 caspase binding(GO:0089720)
0.1 2.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 0.5 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 0.3 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 0.8 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.1 0.3 GO:0052871 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.1 0.4 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.1 0.4 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.4 GO:0033265 choline binding(GO:0033265)
0.1 1.1 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 1.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.6 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1 0.3 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.3 GO:0042019 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.1 1.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 1.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 0.5 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.2 GO:0034437 glycoprotein transporter activity(GO:0034437)
0.1 2.4 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.2 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.1 0.3 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 0.6 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.2 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 0.2 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.1 GO:0019959 interleukin-8 binding(GO:0019959)
0.0 0.4 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.6 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 1.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.3 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 1.8 GO:0043236 laminin binding(GO:0043236)
0.0 0.2 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.9 GO:0031432 titin binding(GO:0031432)
0.0 0.2 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.6 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 1.0 GO:0005549 odorant binding(GO:0005549)
0.0 1.1 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.6 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.7 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.1 GO:0004008 copper-exporting ATPase activity(GO:0004008) phosphoglycerate kinase activity(GO:0004618) copper-transporting ATPase activity(GO:0043682)
0.0 1.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.9 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.5 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.2 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 3.9 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 1.6 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.4 GO:0015643 toxic substance binding(GO:0015643)
0.0 1.0 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.2 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.2 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.3 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.3 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.6 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.3 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.4 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.2 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.5 GO:0031489 myosin V binding(GO:0031489)
0.0 2.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 1.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.0 0.1 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.4 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.3 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.2 GO:0047035 alcohol dehydrogenase (NAD) activity(GO:0004022) testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.1 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.4 GO:0001848 complement binding(GO:0001848)
0.0 1.1 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.1 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.0 GO:0005042 netrin receptor activity(GO:0005042)
0.0 2.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.4 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.0 1.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.1 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.3 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.6 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.3 GO:0051010 microtubule plus-end binding(GO:0051010)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 1.3 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.9 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 1.8 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 1.4 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.2 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.9 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 4.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.8 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.5 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.8 PID ATR PATHWAY ATR signaling pathway
0.0 0.4 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.7 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.6 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.1 PID IL6 7 PATHWAY IL6-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 1.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 1.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.7 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 0.6 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.3 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.9 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.9 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.8 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 3.4 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 2.0 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 1.2 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 3.4 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 4.6 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.6 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.9 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.5 REACTOME GABA B RECEPTOR ACTIVATION Genes involved in GABA B receptor activation
0.0 0.5 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 2.7 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.0 1.2 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.6 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.5 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation