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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for DBX2_HLX

Z-value: 0.45

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Transcription factors associated with DBX2_HLX

Gene Symbol Gene ID Gene Info
DBX2
ENSG00000185610.6 DBX2
HLX
ENSG00000136630.13 HLX

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HLXhg38_v1_chr1_+_220879434_2208794570.096.4e-01Click!

Activity profile of DBX2_HLX motif

Sorted Z-values of DBX2_HLX motif

Network of associatons between targets according to the STRING database.

First level regulatory network of DBX2_HLX

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr1_-_197067234 1.09 ENST00000367412.2
F13B
coagulation factor XIII B chain
chr3_-_142029108 1.08 ENST00000497579.5
TFDP2
transcription factor Dp-2
chr9_+_12693327 1.06 ENST00000388918.10
TYRP1
tyrosinase related protein 1
chr6_-_25874212 0.91 ENST00000361703.10
ENST00000397060.8
SLC17A3
solute carrier family 17 member 3
chr7_+_123601815 0.91 ENST00000451215.6
ASB15
ankyrin repeat and SOCS box containing 15
chr7_+_123601836 0.82 ENST00000434204.5
ASB15
ankyrin repeat and SOCS box containing 15
chr6_-_27912396 0.80 ENST00000303324.4
OR2B2
olfactory receptor family 2 subfamily B member 2
chr8_-_85341705 0.70 ENST00000517618.5
CA1
carbonic anhydrase 1
chr3_-_194351290 0.66 ENST00000429275.1
ENST00000323830.4
CPN2
carboxypeptidase N subunit 2
chr20_-_7940444 0.63 ENST00000378789.4
HAO1
hydroxyacid oxidase 1
chr11_-_5301946 0.62 ENST00000380224.2
OR51B4
olfactory receptor family 51 subfamily B member 4
chr5_-_147401591 0.57 ENST00000520473.1
DPYSL3
dihydropyrimidinase like 3
chr4_-_149815826 0.57 ENST00000636793.2
ENST00000636414.1
IQCM
IQ motif containing M
chr2_+_102337148 0.57 ENST00000311734.6
ENST00000409584.5
IL1RL1
interleukin 1 receptor like 1
chr4_-_159035226 0.56 ENST00000434826.3
C4orf45
chromosome 4 open reading frame 45
chr15_-_19988117 0.56 ENST00000558565.2
IGHV3OR15-7
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr12_-_10826358 0.53 ENST00000240619.2
TAS2R10
taste 2 receptor member 10
chr9_+_27109393 0.45 ENST00000406359.8
TEK
TEK receptor tyrosine kinase
chr19_+_53962925 0.44 ENST00000270458.4
CACNG8
calcium voltage-gated channel auxiliary subunit gamma 8
chr12_-_8066331 0.43 ENST00000546241.1
ENST00000307637.5
C3AR1
complement C3a receptor 1
chr12_-_91111460 0.43 ENST00000266718.5
LUM
lumican
chr21_-_30497160 0.43 ENST00000334058.3
KRTAP19-4
keratin associated protein 19-4
chr5_-_140346596 0.43 ENST00000230990.7
HBEGF
heparin binding EGF like growth factor
chr3_-_33645433 0.43 ENST00000635664.1
ENST00000485378.6
ENST00000313350.10
ENST00000487200.5
CLASP2
cytoplasmic linker associated protein 2
chr11_+_35180279 0.41 ENST00000531873.5
CD44
CD44 molecule (Indian blood group)
chr9_-_21482313 0.40 ENST00000448696.4
IFNE
interferon epsilon
chr4_+_155666718 0.40 ENST00000621234.4
ENST00000511108.5
GUCY1A1
guanylate cyclase 1 soluble subunit alpha 1
chr19_+_926001 0.39 ENST00000263620.8
ARID3A
AT-rich interaction domain 3A
chr16_+_56191476 0.39 ENST00000262493.12
GNAO1
G protein subunit alpha o1
chr3_+_133124807 0.39 ENST00000508711.5
TMEM108
transmembrane protein 108
chr5_-_126595237 0.38 ENST00000637206.1
ENST00000553117.5
ALDH7A1
aldehyde dehydrogenase 7 family member A1
chr1_+_76867469 0.38 ENST00000477717.6
ST6GALNAC5
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr10_+_89392546 0.38 ENST00000546318.2
ENST00000371804.4
IFIT1
interferon induced protein with tetratricopeptide repeats 1
chrX_-_15314543 0.36 ENST00000344384.8
ASB11
ankyrin repeat and SOCS box containing 11
chr1_-_247758680 0.36 ENST00000408896.4
OR1C1
olfactory receptor family 1 subfamily C member 1
chr21_+_32298945 0.36 ENST00000339944.4
MRAP
melanocortin 2 receptor accessory protein
chr12_-_84892120 0.34 ENST00000680379.1
SLC6A15
solute carrier family 6 member 15
chr6_+_123804141 0.34 ENST00000368416.5
NKAIN2
sodium/potassium transporting ATPase interacting 2
chr7_+_142111739 0.34 ENST00000550469.6
ENST00000477922.3
MGAM2
maltase-glucoamylase 2 (putative)
chr10_+_96000091 0.34 ENST00000424464.5
ENST00000410012.6
ENST00000344386.3
CC2D2B
coiled-coil and C2 domain containing 2B
chr1_+_76074698 0.33 ENST00000328299.4
ST6GALNAC3
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr6_+_85449584 0.33 ENST00000369651.7
NT5E
5'-nucleotidase ecto
chr11_-_122116215 0.33 ENST00000560104.2
BLID
BH3-like motif containing, cell death inducer
chr11_-_107858777 0.33 ENST00000525815.6
SLC35F2
solute carrier family 35 member F2
chr19_-_3557563 0.33 ENST00000389395.7
ENST00000355415.7
MFSD12
major facilitator superfamily domain containing 12
chr17_-_41149823 0.32 ENST00000343246.6
KRTAP4-5
keratin associated protein 4-5
chr7_-_93890160 0.31 ENST00000451238.1
TFPI2
tissue factor pathway inhibitor 2
chr1_+_86468902 0.31 ENST00000394711.2
CLCA1
chloride channel accessory 1
chr3_-_48089203 0.31 ENST00000468075.2
ENST00000360240.10
MAP4
microtubule associated protein 4
chr2_+_54558348 0.31 ENST00000333896.5
SPTBN1
spectrin beta, non-erythrocytic 1
chr19_+_9185594 0.30 ENST00000344248.4
OR7D2
olfactory receptor family 7 subfamily D member 2
chr15_-_79971164 0.30 ENST00000335661.6
ENST00000267953.4
ENST00000677151.1
BCL2A1
BCL2 related protein A1
chr3_-_112845950 0.29 ENST00000398214.5
CD200R1L
CD200 receptor 1 like
chr11_-_7796942 0.29 ENST00000329434.3
OR5P2
olfactory receptor family 5 subfamily P member 2
chr20_+_3786772 0.29 ENST00000344256.10
ENST00000379598.9
CDC25B
cell division cycle 25B
chr9_-_21305313 0.29 ENST00000610521.2
IFNA5
interferon alpha 5
chr7_-_122699108 0.29 ENST00000340112.3
RNF133
ring finger protein 133
chr10_+_127998126 0.27 ENST00000455661.5
PTPRE
protein tyrosine phosphatase receptor type E
chr12_-_95116967 0.27 ENST00000551521.5
FGD6
FYVE, RhoGEF and PH domain containing 6
chr9_+_36572854 0.27 ENST00000543751.5
ENST00000536860.5
ENST00000541717.4
ENST00000536329.5
ENST00000536987.5
ENST00000298048.7
ENST00000495529.5
ENST00000545008.5
MELK
maternal embryonic leucine zipper kinase
chr19_-_42877988 0.27 ENST00000597058.1
PSG1
pregnancy specific beta-1-glycoprotein 1
chr2_-_224947030 0.27 ENST00000409592.7
DOCK10
dedicator of cytokinesis 10
chr15_+_76336755 0.26 ENST00000290759.9
ISL2
ISL LIM homeobox 2
chr6_-_76072654 0.26 ENST00000369950.8
ENST00000611179.4
ENST00000369963.5
IMPG1
interphotoreceptor matrix proteoglycan 1
chr19_+_16829387 0.26 ENST00000248054.10
ENST00000596802.5
ENST00000379803.5
SIN3B
SIN3 transcription regulator family member B
chr13_+_31739542 0.25 ENST00000380314.2
RXFP2
relaxin family peptide receptor 2
chrX_+_136205982 0.25 ENST00000628568.1
FHL1
four and a half LIM domains 1
chr4_-_109801978 0.25 ENST00000510800.1
ENST00000512148.5
ENST00000394634.7
ENST00000394635.8
ENST00000645635.1
CFI
ENSG00000285330.1
complement factor I
novel protein
chr12_-_7503841 0.25 ENST00000359156.8
CD163
CD163 molecule
chr4_+_94207596 0.25 ENST00000359052.8
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr11_-_35265696 0.25 ENST00000464522.2
SLC1A2
solute carrier family 1 member 2
chr16_+_81645352 0.25 ENST00000398040.8
CMIP
c-Maf inducing protein
chr6_+_130018565 0.25 ENST00000361794.7
ENST00000526087.5
ENST00000533560.5
L3MBTL3
L3MBTL histone methyl-lysine binding protein 3
chr2_+_186694007 0.24 ENST00000304698.10
FAM171B
family with sequence similarity 171 member B
chr7_+_138076453 0.24 ENST00000242375.8
ENST00000411726.6
AKR1D1
aldo-keto reductase family 1 member D1
chr2_+_89936859 0.24 ENST00000474213.1
IGKV2D-30
immunoglobulin kappa variable 2D-30
chr2_+_90172802 0.24 ENST00000390277.3
IGKV3D-11
immunoglobulin kappa variable 3D-11
chr7_+_134891566 0.24 ENST00000424922.5
ENST00000495522.1
CALD1
caldesmon 1
chr1_+_212035717 0.23 ENST00000366991.5
DTL
denticleless E3 ubiquitin protein ligase homolog
chr22_-_28712136 0.23 ENST00000464581.6
CHEK2
checkpoint kinase 2
chr11_-_123654939 0.23 ENST00000657191.1
SCN3B
sodium voltage-gated channel beta subunit 3
chr8_-_13276491 0.23 ENST00000512044.6
DLC1
DLC1 Rho GTPase activating protein
chr13_+_31739520 0.23 ENST00000298386.7
RXFP2
relaxin family peptide receptor 2
chr4_-_137532452 0.23 ENST00000412923.6
ENST00000511115.5
ENST00000344876.9
ENST00000507846.5
ENST00000510305.5
ENST00000611581.1
PCDH18
protocadherin 18
chr2_+_102418642 0.23 ENST00000264260.6
IL18RAP
interleukin 18 receptor accessory protein
chr17_-_445939 0.22 ENST00000329099.4
RFLNB
refilin B
chr9_+_74615582 0.22 ENST00000396204.2
RORB
RAR related orphan receptor B
chr19_-_4535221 0.22 ENST00000381848.7
ENST00000586133.1
PLIN5
perilipin 5
chr10_+_52128343 0.21 ENST00000672084.1
PRKG1
protein kinase cGMP-dependent 1
chr2_+_181985846 0.21 ENST00000682840.1
ENST00000409137.7
ENST00000280295.7
PPP1R1C
protein phosphatase 1 regulatory inhibitor subunit 1C
chr4_-_122621011 0.21 ENST00000611104.2
ENST00000648588.1
IL21
interleukin 21
chr1_-_247760556 0.21 ENST00000641256.1
OR1C1
olfactory receptor family 1 subfamily C member 1
chr16_+_11965234 0.21 ENST00000562385.1
TNFRSF17
TNF receptor superfamily member 17
chr6_-_87095059 0.21 ENST00000369582.6
ENST00000610310.3
ENST00000630630.2
ENST00000627148.3
ENST00000625577.1
CGA
glycoprotein hormones, alpha polypeptide
chr2_-_189179754 0.21 ENST00000374866.9
ENST00000618828.1
COL5A2
collagen type V alpha 2 chain
chr1_+_244352627 0.21 ENST00000366537.5
ENST00000308105.5
C1orf100
chromosome 1 open reading frame 100
chr11_-_60183191 0.21 ENST00000412309.6
MS4A6A
membrane spanning 4-domains A6A
chr5_-_22853320 0.21 ENST00000504376.6
ENST00000382254.6
CDH12
cadherin 12
chr2_+_29097705 0.21 ENST00000401605.5
ENST00000401617.6
CLIP4
CAP-Gly domain containing linker protein family member 4
chr5_-_112419251 0.21 ENST00000261486.6
EPB41L4A
erythrocyte membrane protein band 4.1 like 4A
chr15_+_78565556 0.21 ENST00000559554.5
CHRNA5
cholinergic receptor nicotinic alpha 5 subunit
chr7_+_130486171 0.21 ENST00000341441.9
ENST00000416162.7
MEST
mesoderm specific transcript
chrX_+_15507302 0.21 ENST00000342014.6
BMX
BMX non-receptor tyrosine kinase
chrX_+_83508284 0.20 ENST00000644024.2
POU3F4
POU class 3 homeobox 4
chr9_-_92404559 0.20 ENST00000262551.8
ENST00000375561.10
OGN
osteoglycin
chr16_+_11345429 0.20 ENST00000576027.1
ENST00000312499.6
ENST00000648619.1
RMI2
RecQ mediated genome instability 2
chr3_-_150703943 0.20 ENST00000491361.5
ERICH6
glutamate rich 6
chr6_-_110179995 0.20 ENST00000392586.5
ENST00000419252.1
ENST00000359451.6
ENST00000392588.5
WASF1
WASP family member 1
chr16_-_20404731 0.20 ENST00000302451.9
PDILT
protein disulfide isomerase like, testis expressed
chr9_-_39239174 0.20 ENST00000358144.6
CNTNAP3
contactin associated protein family member 3
chr4_+_70050431 0.20 ENST00000511674.5
ENST00000246896.8
HTN1
histatin 1
chr12_-_11395556 0.20 ENST00000565533.1
ENST00000389362.6
ENST00000546254.3
PRB2
PRB1
proline rich protein BstNI subfamily 2
proline rich protein BstNI subfamily 1
chr11_-_117316230 0.20 ENST00000313005.11
ENST00000528053.5
BACE1
beta-secretase 1
chr7_-_36985060 0.20 ENST00000396040.6
ELMO1
engulfment and cell motility 1
chr7_+_130486324 0.20 ENST00000427521.6
ENST00000378576.9
MEST
mesoderm specific transcript
chr2_-_157444044 0.19 ENST00000264192.8
CYTIP
cytohesin 1 interacting protein
chr5_+_55160161 0.19 ENST00000296734.6
ENST00000515370.1
ENST00000503787.6
GPX8
glutathione peroxidase 8 (putative)
chr3_+_102099244 0.19 ENST00000491959.5
ZPLD1
zona pellucida like domain containing 1
chr15_+_67125707 0.19 ENST00000540846.6
SMAD3
SMAD family member 3
chr6_+_29111560 0.19 ENST00000377169.2
OR2J3
olfactory receptor family 2 subfamily J member 3
chr3_+_172754457 0.19 ENST00000441497.6
ECT2
epithelial cell transforming 2
chr11_+_49028823 0.19 ENST00000332682.9
TRIM49B
tripartite motif containing 49B
chr14_-_67412112 0.18 ENST00000216446.9
PLEK2
pleckstrin 2
chr10_-_5404819 0.18 ENST00000380419.8
ENST00000479328.1
TUBAL3
tubulin alpha like 3
chr9_+_27109135 0.18 ENST00000519097.5
ENST00000615002.4
TEK
TEK receptor tyrosine kinase
chr3_-_151203201 0.18 ENST00000480322.1
ENST00000309180.6
GPR171
G protein-coupled receptor 171
chr15_+_78565507 0.18 ENST00000299565.9
CHRNA5
cholinergic receptor nicotinic alpha 5 subunit
chr12_+_75480745 0.18 ENST00000266659.8
GLIPR1
GLI pathogenesis related 1
chr17_+_18744026 0.18 ENST00000308799.8
ENST00000395665.9
ENST00000301938.4
FBXW10
F-box and WD repeat domain containing 10
chr15_+_21579912 0.18 ENST00000628444.1
LINC02203
long intergenic non-protein coding RNA 2203
chr12_+_75480800 0.18 ENST00000456650.7
GLIPR1
GLI pathogenesis related 1
chr8_-_48921419 0.17 ENST00000020945.4
SNAI2
snail family transcriptional repressor 2
chr10_+_60778331 0.17 ENST00000519078.6
ENST00000316629.8
ENST00000395284.8
CDK1
cyclin dependent kinase 1
chr1_+_152811971 0.17 ENST00000360090.4
LCE1B
late cornified envelope 1B
chr6_-_107824294 0.17 ENST00000369020.8
ENST00000369022.6
SCML4
Scm polycomb group protein like 4
chr12_+_26011713 0.17 ENST00000542004.5
RASSF8
Ras association domain family member 8
chr9_-_21368962 0.17 ENST00000610660.1
IFNA13
interferon alpha 13
chr4_-_151227881 0.17 ENST00000652233.1
ENST00000514152.5
SH3D19
SH3 domain containing 19
chr13_-_46105009 0.17 ENST00000439329.5
ENST00000674625.1
ENST00000181383.10
CPB2
carboxypeptidase B2
chr11_+_121102666 0.17 ENST00000264037.2
TECTA
tectorin alpha
chr17_-_3127551 0.17 ENST00000328890.3
OR1G1
olfactory receptor family 1 subfamily G member 1
chr15_+_41286011 0.17 ENST00000661438.1
ENSG00000285920.2
novel protein
chr9_+_27109200 0.17 ENST00000380036.10
TEK
TEK receptor tyrosine kinase
chr1_+_196888014 0.17 ENST00000367416.6
ENST00000608469.6
ENST00000251424.8
ENST00000367418.2
CFHR4
complement factor H related 4
chr10_+_69088096 0.17 ENST00000242465.4
SRGN
serglycin
chr7_+_142800957 0.17 ENST00000466254.1
TRBC2
T cell receptor beta constant 2
chr12_-_86256267 0.16 ENST00000620241.4
MGAT4C
MGAT4 family member C
chr2_+_190137760 0.16 ENST00000396974.2
C2orf88
chromosome 2 open reading frame 88
chr12_+_75481204 0.16 ENST00000550491.1
GLIPR1
GLI pathogenesis related 1
chr1_+_84164962 0.16 ENST00000614872.4
ENST00000394839.6
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr12_+_8822610 0.16 ENST00000299698.12
A2ML1
alpha-2-macroglobulin like 1
chr3_+_44874606 0.16 ENST00000296125.9
TGM4
transglutaminase 4
chr9_-_21217311 0.16 ENST00000380216.1
IFNA16
interferon alpha 16
chr1_-_153150884 0.16 ENST00000368748.5
SPRR2G
small proline rich protein 2G
chr21_-_30813270 0.15 ENST00000329621.6
KRTAP8-1
keratin associated protein 8-1
chr1_+_149782671 0.15 ENST00000444948.5
ENST00000369168.5
FCGR1A
Fc fragment of IgG receptor Ia
chr17_+_43847142 0.15 ENST00000377203.8
ENST00000539718.5
ENST00000588884.1
ENST00000293396.12
ENST00000586233.5
CD300LG
CD300 molecule like family member g
chr6_+_29301701 0.15 ENST00000641895.1
OR14J1
olfactory receptor family 14 subfamily J member 1
chr22_+_44752552 0.15 ENST00000389774.6
ENST00000356099.11
ENST00000396119.6
ENST00000336963.8
ENST00000412433.5
ARHGAP8
Rho GTPase activating protein 8
chr14_-_106593319 0.15 ENST00000390627.3
IGHV3-53
immunoglobulin heavy variable 3-53
chr2_-_162838728 0.15 ENST00000328032.8
ENST00000332142.10
KCNH7
potassium voltage-gated channel subfamily H member 7
chr8_+_12104389 0.15 ENST00000400085.7
ZNF705D
zinc finger protein 705D
chr13_+_76948500 0.15 ENST00000377462.6
ACOD1
aconitate decarboxylase 1
chr11_-_35360050 0.15 ENST00000644868.1
ENST00000643454.1
ENST00000646080.1
SLC1A2
solute carrier family 1 member 2
chr14_-_70080180 0.15 ENST00000394330.6
ENST00000533541.1
ENST00000216568.11
SLC8A3
solute carrier family 8 member A3
chr17_-_40665121 0.15 ENST00000394052.5
KRT222
keratin 222
chr7_+_134891400 0.15 ENST00000393118.6
CALD1
caldesmon 1
chr5_-_88823763 0.14 ENST00000635898.1
ENST00000626391.2
ENST00000628656.2
MEF2C
myocyte enhancer factor 2C
chr11_+_57597563 0.14 ENST00000619430.2
ENST00000457869.1
ENST00000340687.10
ENST00000278407.9
ENST00000378323.8
ENST00000378324.6
ENST00000403558.1
SERPING1
serpin family G member 1
chr6_+_34757473 0.14 ENST00000244520.10
ENST00000374018.5
ENST00000374017.3
SNRPC
small nuclear ribonucleoprotein polypeptide C
chr3_-_112829367 0.14 ENST00000448932.4
ENST00000617549.3
CD200R1L
CD200 receptor 1 like
chr6_+_154039333 0.14 ENST00000428397.6
OPRM1
opioid receptor mu 1
chr10_-_114144599 0.14 ENST00000428953.1
CCDC186
coiled-coil domain containing 186
chr19_-_42427379 0.14 ENST00000244289.9
LIPE
lipase E, hormone sensitive type
chr5_+_151020438 0.14 ENST00000622181.4
ENST00000614343.4
ENST00000388825.9
ENST00000521650.5
ENST00000517973.1
GPX3
glutathione peroxidase 3
chr10_+_100462969 0.14 ENST00000343737.6
WNT8B
Wnt family member 8B
chr21_+_14216145 0.13 ENST00000400577.4
RBM11
RNA binding motif protein 11
chr8_-_113377125 0.13 ENST00000343508.7
CSMD3
CUB and Sushi multiple domains 3
chr10_-_13972355 0.13 ENST00000264546.10
FRMD4A
FERM domain containing 4A
chr2_-_177888728 0.13 ENST00000389683.7
PDE11A
phosphodiesterase 11A
chr3_+_63443076 0.13 ENST00000295894.9
SYNPR
synaptoporin
chr17_+_80544817 0.13 ENST00000306801.8
ENST00000570891.5
RPTOR
regulatory associated protein of MTOR complex 1
chr19_-_51417791 0.13 ENST00000353836.9
SIGLEC10
sialic acid binding Ig like lectin 10
chr14_+_103385450 0.13 ENST00000416682.6
MARK3
microtubule affinity regulating kinase 3
chr4_+_87832917 0.13 ENST00000395102.8
ENST00000497649.6
ENST00000540395.1
ENST00000560249.5
ENST00000511670.5
ENST00000361056.3
MEPE
matrix extracellular phosphoglycoprotein
chrX_+_154304923 0.13 ENST00000426989.5
ENST00000426203.5
ENST00000369912.2
TKTL1
transketolase like 1
chr2_+_90038848 0.13 ENST00000390270.2
IGKV3D-20
immunoglobulin kappa variable 3D-20
chr4_-_162163955 0.13 ENST00000379164.8
FSTL5
follistatin like 5
chr4_-_76036060 0.13 ENST00000306621.8
CXCL11
C-X-C motif chemokine ligand 11
chr19_-_51417700 0.12 ENST00000529627.1
ENST00000439889.6
SIGLEC10
sialic acid binding Ig like lectin 10
chr4_+_70383123 0.12 ENST00000304915.8
SMR3B
submaxillary gland androgen regulated protein 3B
chr16_-_28211476 0.12 ENST00000569951.1
ENST00000565698.5
XPO6
exportin 6
chr18_+_45615473 0.12 ENST00000255226.11
SLC14A2
solute carrier family 14 member 2
chr6_+_46793379 0.12 ENST00000230588.9
ENST00000611727.2
MEP1A
meprin A subunit alpha
chr10_+_89301932 0.12 ENST00000371826.4
ENST00000679755.1
IFIT2
interferon induced protein with tetratricopeptide repeats 2
chr15_+_21651844 0.12 ENST00000623441.1
OR4N4C
olfactory receptor family 4 subfamily N member 4C
chr14_+_21868822 0.12 ENST00000390436.2
TRAV13-1
T cell receptor alpha variable 13-1
chr11_+_4329865 0.12 ENST00000640302.1
SSU72P3
SSU72 pseudogene 3
chr17_+_29941605 0.12 ENST00000394835.7
EFCAB5
EF-hand calcium binding domain 5
chr8_-_61646807 0.12 ENST00000522919.5
ASPH
aspartate beta-hydroxylase

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.1 0.9 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.8 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 0.3 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.4 GO:0031455 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.1 0.3 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.1 0.2 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.1 0.6 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 1.1 GO:1900378 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.1 0.2 GO:0030573 bile acid catabolic process(GO:0030573)
0.1 0.6 GO:0009441 glycolate metabolic process(GO:0009441)
0.1 0.3 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 0.2 GO:0061182 negative regulation of chondrocyte development(GO:0061182)
0.1 0.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.4 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.2 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 0.3 GO:0006196 AMP catabolic process(GO:0006196) adenosine biosynthetic process(GO:0046086)
0.0 0.1 GO:0001868 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.0 0.4 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.4 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.2 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 1.0 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.2 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.0 0.2 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.2 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.5 GO:0015820 leucine transport(GO:0015820)
0.0 0.6 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.5 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:1902573 positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.0 0.5 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.2 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.1 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.4 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.2 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.1 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.0 0.4 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.1 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.0 0.1 GO:0071393 propionate metabolic process(GO:0019541) cellular response to progesterone stimulus(GO:0071393) tolerance induction to lipopolysaccharide(GO:0072573)
0.0 0.1 GO:0061358 negative regulation of Wnt protein secretion(GO:0061358)
0.0 0.1 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.0 0.2 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0 0.0 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0 0.2 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.1 GO:0035915 pore formation in membrane of other organism(GO:0035915)
0.0 0.1 GO:0006772 thiamine metabolic process(GO:0006772)
0.0 0.2 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.3 GO:0007144 female meiosis I(GO:0007144)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.1 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.0 0.2 GO:0097338 response to clozapine(GO:0097338)
0.0 0.0 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.0 0.2 GO:0090166 regulation of Schwann cell differentiation(GO:0014038) Golgi disassembly(GO:0090166)
0.0 1.0 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.6 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.3 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.6 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.7 GO:0097503 sialylation(GO:0097503)
0.0 0.2 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.3 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.5 GO:0001556 oocyte maturation(GO:0001556)
0.0 0.2 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.0 0.1 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.1 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.0 2.6 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.1 GO:0071233 cellular response to leucine(GO:0071233)
0.0 0.1 GO:0019732 antifungal humoral response(GO:0019732)
0.0 0.3 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.0 0.2 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 0.0 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 0.1 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.0 0.8 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.5 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.1 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 0.1 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.1 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 1.6 GO:0030449 regulation of complement activation(GO:0030449)
0.0 0.0 GO:0044771 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.2 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.1 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.2 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.0 0.0 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.1 GO:0016139 glycoside catabolic process(GO:0016139)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0030849 X chromosome(GO:0000805) autosome(GO:0030849)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.2 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.0 1.1 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.3 GO:0032437 cuticular plate(GO:0032437)
0.0 0.2 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 0.4 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.4 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.4 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.2 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.1 GO:0071753 dimeric IgA immunoglobulin complex(GO:0071750) secretory dimeric IgA immunoglobulin complex(GO:0071752) IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.1 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0000243 commitment complex(GO:0000243)
0.0 0.0 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.0 GO:0034515 proteasome storage granule(GO:0034515)
0.0 0.8 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.3 GO:0042588 zymogen granule(GO:0042588)
0.0 1.0 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.0 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.2 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0052852 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.2 0.6 GO:0002113 interleukin-33 binding(GO:0002113)
0.1 0.9 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 0.3 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.1 0.3 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.1 0.3 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.1 0.7 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.7 GO:0004064 arylesterase activity(GO:0004064)
0.1 1.0 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 0.3 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.0 0.2 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.6 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.5 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.1 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.0 0.2 GO:0035473 lipase binding(GO:0035473)
0.0 0.2 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0004979 beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.0 0.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.1 GO:0004802 transketolase activity(GO:0004802)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.4 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.5 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.0 0.1 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.5 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.3 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0019862 IgA binding(GO:0019862)
0.0 0.4 GO:0005549 odorant binding(GO:0005549)
0.0 2.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.0 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.0 0.3 GO:0051400 BH domain binding(GO:0051400)
0.0 0.4 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.2 GO:0031005 filamin binding(GO:0031005)
0.0 0.1 GO:0004372 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0 0.1 GO:0008430 selenium binding(GO:0008430)
0.0 1.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.2 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.7 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.2 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.5 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.7 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.6 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 2.7 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.5 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters