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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)
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Results for DPRX
Z-value: 0.52
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Transcription factors associated with DPRX
Network of associatons between targets according to the STRING database.
First level regulatory network of DPRX
| Promoter | Score | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr7_+_123601815 Show fit | 1.10 |
ENST00000451215.6
|
ankyrin repeat and SOCS box containing 15 |
|
| chr7_+_123601836 Show fit | 1.10 |
ENST00000434204.5
|
ankyrin repeat and SOCS box containing 15 |
|
| chr19_+_7030578 Show fit | 0.65 |
ENST00000329753.5
|
methyl-CpG binding domain protein 3 like 5 |
|
| chr19_-_7021431 Show fit | 0.55 |
ENST00000636986.2
ENST00000637800.1 |
methyl-CpG binding domain protein 3 like 2B |
|
| chr9_+_98943705 Show fit | 0.53 |
ENST00000610452.1
|
collagen type XV alpha 1 chain |
|
| chr9_-_13279407 Show fit | 0.52 |
ENST00000546205.5
|
multiple PDZ domain crumbs cell polarity complex component |
|
| chr19_-_7040179 Show fit | 0.52 |
ENST00000381394.9
|
methyl-CpG binding domain protein 3 like 4 |
|
| chr22_-_30471986 Show fit | 0.51 |
ENST00000401751.5
ENST00000402286.5 ENST00000403066.5 ENST00000215812.9 |
SEC14 like lipid binding 3 |
|
| chr19_+_7049321 Show fit | 0.49 |
ENST00000381393.3
|
methyl-CpG binding domain protein 3 like 2 |
|
| chr16_-_28403841 Show fit | 0.46 |
ENST00000398944.7
ENST00000380876.5 |
eukaryotic translation initiation factor 3 subunit C like |
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.6 | GO:0006346 | methylation-dependent chromatin silencing(GO:0006346) |
| 0.3 | 0.8 | GO:0007309 | oocyte construction(GO:0007308) oocyte axis specification(GO:0007309) oocyte anterior/posterior axis specification(GO:0007314) pole plasm assembly(GO:0007315) maternal determination of anterior/posterior axis, embryo(GO:0008358) P granule organization(GO:0030719) |
| 0.1 | 0.8 | GO:0070779 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
| 0.2 | 0.5 | GO:0001545 | primary ovarian follicle growth(GO:0001545) |
| 0.0 | 0.4 | GO:0071286 | cellular response to magnesium ion(GO:0071286) |
| 0.0 | 0.4 | GO:0001865 | NK T cell differentiation(GO:0001865) |
| 0.1 | 0.3 | GO:0002581 | negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) |
| 0.1 | 0.3 | GO:0086097 | phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097) |
| 0.1 | 0.3 | GO:0051758 | homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758) |
| 0.1 | 0.3 | GO:0002357 | defense response to tumor cell(GO:0002357) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.8 | GO:0071546 | pi-body(GO:0071546) |
| 0.0 | 0.8 | GO:0043220 | Schmidt-Lanterman incisure(GO:0043220) |
| 0.0 | 0.8 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 0.0 | 0.8 | GO:0030673 | axolemma(GO:0030673) |
| 0.0 | 0.6 | GO:0030478 | actin cap(GO:0030478) |
| 0.0 | 0.5 | GO:0098651 | basement membrane collagen trimer(GO:0098651) |
| 0.0 | 0.4 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.0 | 0.3 | GO:0044194 | cytolytic granule(GO:0044194) |
| 0.1 | 0.2 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
| 0.1 | 0.2 | GO:0005588 | collagen type V trimer(GO:0005588) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.7 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.0 | 0.9 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.1 | 0.8 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.1 | 0.7 | GO:0032395 | MHC class II receptor activity(GO:0032395) |
| 0.0 | 0.6 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.2 | 0.5 | GO:0004963 | follicle-stimulating hormone receptor activity(GO:0004963) |
| 0.1 | 0.4 | GO:0048763 | calcium-induced calcium release activity(GO:0048763) |
| 0.1 | 0.3 | GO:0001596 | angiotensin type I receptor activity(GO:0001596) |
| 0.0 | 0.3 | GO:0038049 | transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) |
| 0.0 | 0.3 | GO:0019958 | C-X-C chemokine binding(GO:0019958) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | ST G ALPHA S PATHWAY | G alpha s Pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.7 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.0 | 0.5 | REACTOME HORMONE LIGAND BINDING RECEPTORS | Genes involved in Hormone ligand-binding receptors |
| 0.0 | 0.3 | REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 0.0 | 0.3 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
| 0.0 | 0.2 | REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
| 0.0 | 0.2 | REACTOME G2 M DNA DAMAGE CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |