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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for DRGX_PROP1

Z-value: 0.92

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Transcription factors associated with DRGX_PROP1

Gene Symbol Gene ID Gene Info
DRGX
ENSG00000165606.10 DRGX
PROP1
ENSG00000175325.2 PROP1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PROP1hg38_v1_chr5_-_177996242_177996242-0.596.1e-04Click!

Activity profile of DRGX_PROP1 motif

Sorted Z-values of DRGX_PROP1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of DRGX_PROP1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr20_+_33235987 12.16 ENST00000375422.6
ENST00000375413.8
ENST00000354297.9
BPIFA1
BPI fold containing family A member 1
chr16_-_53052849 10.80 ENST00000619363.2
ENSG00000277639.2
novel protein
chr13_+_50015254 5.70 ENST00000360473.8
KCNRG
potassium channel regulator
chr9_-_34397800 4.49 ENST00000297623.7
C9orf24
chromosome 9 open reading frame 24
chr4_-_99435396 4.48 ENST00000209665.8
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr4_-_99435336 4.29 ENST00000437033.7
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr4_-_99435134 4.17 ENST00000476959.5
ENST00000482593.5
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr4_+_94974984 3.88 ENST00000672698.1
BMPR1B
bone morphogenetic protein receptor type 1B
chr5_-_55173173 3.15 ENST00000296733.5
ENST00000322374.10
ENST00000381375.7
CDC20B
cell division cycle 20B
chr14_+_75069577 3.12 ENST00000238686.8
ZC2HC1C
zinc finger C2HC-type containing 1C
chr5_-_160852200 2.91 ENST00000327245.10
ATP10B
ATPase phospholipid transporting 10B (putative)
chr5_-_138139382 2.86 ENST00000265191.4
NME5
NME/NM23 family member 5
chrX_+_35919725 2.83 ENST00000297866.9
ENST00000378653.8
CFAP47
cilia and flagella associated protein 47
chr6_+_87407965 2.81 ENST00000369562.9
CFAP206
cilia and flagella associated protein 206
chr1_-_91906280 2.65 ENST00000370399.6
TGFBR3
transforming growth factor beta receptor 3
chr9_-_123184233 2.30 ENST00000447404.6
STRBP
spermatid perinuclear RNA binding protein
chr8_-_10655137 2.21 ENST00000382483.4
RP1L1
RP1 like 1
chr5_+_36606355 2.20 ENST00000681909.1
ENST00000513903.5
ENST00000681795.1
ENST00000680125.1
ENST00000612708.5
ENST00000680232.1
ENST00000681776.1
ENST00000681926.1
ENST00000679958.1
ENST00000265113.9
ENST00000504121.5
ENST00000512374.1
ENST00000613445.5
ENST00000679983.1
SLC1A3
solute carrier family 1 member 3
chr5_+_90640718 2.20 ENST00000640403.1
ADGRV1
adhesion G protein-coupled receptor V1
chr6_-_75363003 2.04 ENST00000370020.1
FILIP1
filamin A interacting protein 1
chr10_-_60141004 1.78 ENST00000355288.6
ANK3
ankyrin 3
chr5_+_141192330 1.77 ENST00000239446.6
PCDHB10
protocadherin beta 10
chr6_-_32941018 1.70 ENST00000418107.3
HLA-DMB
major histocompatibility complex, class II, DM beta
chr5_-_111976925 1.67 ENST00000395634.7
NREP
neuronal regeneration related protein
chr18_-_55321986 1.65 ENST00000570287.6
TCF4
transcription factor 4
chr18_-_55322215 1.64 ENST00000457482.7
TCF4
transcription factor 4
chr6_-_134318097 1.64 ENST00000367858.10
ENST00000533224.1
SGK1
serum/glucocorticoid regulated kinase 1
chr17_+_70075317 1.59 ENST00000589377.1
KCNJ16
potassium inwardly rectifying channel subfamily J member 16
chr1_+_183805105 1.59 ENST00000360851.4
RGL1
ral guanine nucleotide dissociation stimulator like 1
chr17_+_70075215 1.59 ENST00000283936.5
ENST00000615244.4
ENST00000392671.6
KCNJ16
potassium inwardly rectifying channel subfamily J member 16
chr8_-_26867267 1.54 ENST00000380573.4
ADRA1A
adrenoceptor alpha 1A
chr10_+_68106109 1.52 ENST00000540630.5
ENST00000354393.6
MYPN
myopalladin
chr8_+_66126896 1.51 ENST00000353317.9
TRIM55
tripartite motif containing 55
chr2_+_161416273 1.50 ENST00000389554.8
TBR1
T-box brain transcription factor 1
chr2_-_218010202 1.46 ENST00000646520.1
TNS1
tensin 1
chr3_-_3109980 1.43 ENST00000256452.7
ENST00000311981.12
ENST00000430514.6
ENST00000456302.5
IL5RA
interleukin 5 receptor subunit alpha
chr3_+_138621207 1.38 ENST00000464668.5
FAIM
Fas apoptotic inhibitory molecule
chr15_-_52678560 1.37 ENST00000562351.2
ENST00000261844.11
ENST00000399202.8
ENST00000562135.5
FAM214A
family with sequence similarity 214 member A
chr7_+_90709530 1.33 ENST00000406263.5
CDK14
cyclin dependent kinase 14
chr5_+_142770367 1.29 ENST00000645722.2
ENST00000274498.9
ARHGAP26
Rho GTPase activating protein 26
chr5_+_69565122 1.25 ENST00000507595.1
GTF2H2C
GTF2H2 family member C
chr3_+_138621225 1.24 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr11_-_26572254 1.20 ENST00000529533.6
MUC15
mucin 15, cell surface associated
chr12_+_75391078 1.17 ENST00000550916.6
ENST00000378692.7
ENST00000320460.8
ENST00000547164.1
GLIPR1L2
GLIPR1 like 2
chr18_+_58196736 1.17 ENST00000675221.1
NEDD4L
NEDD4 like E3 ubiquitin protein ligase
chr11_-_96343170 1.16 ENST00000524717.6
MAML2
mastermind like transcriptional coactivator 2
chr6_+_116369837 1.15 ENST00000645988.1
DSE
dermatan sulfate epimerase
chr3_-_27722316 1.13 ENST00000449599.4
EOMES
eomesodermin
chr12_-_9999176 1.12 ENST00000298527.10
ENST00000348658.4
CLEC1B
C-type lectin domain family 1 member B
chr1_+_244051275 1.10 ENST00000358704.4
ZBTB18
zinc finger and BTB domain containing 18
chr17_+_55264952 1.09 ENST00000226067.10
HLF
HLF transcription factor, PAR bZIP family member
chr12_-_49187369 1.08 ENST00000547939.6
TUBA1A
tubulin alpha 1a
chr2_+_178320228 1.04 ENST00000315022.2
OSBPL6
oxysterol binding protein like 6
chr14_-_94770102 1.04 ENST00000238558.5
GSC
goosecoid homeobox
chr6_-_111483700 0.99 ENST00000435970.5
ENST00000358835.7
REV3L
REV3 like, DNA directed polymerase zeta catalytic subunit
chr11_-_26567087 0.98 ENST00000436318.6
ENST00000281268.12
MUC15
mucin 15, cell surface associated
chr11_-_26572130 0.97 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr17_+_73232601 0.93 ENST00000359042.6
C17orf80
chromosome 17 open reading frame 80
chr7_-_120858066 0.92 ENST00000222747.8
TSPAN12
tetraspanin 12
chr22_+_25219633 0.90 ENST00000398215.3
CRYBB2
crystallin beta B2
chr7_-_120857124 0.89 ENST00000441017.5
ENST00000424710.5
ENST00000433758.5
TSPAN12
tetraspanin 12
chr11_-_26572102 0.86 ENST00000455601.6
MUC15
mucin 15, cell surface associated
chr5_-_111758061 0.86 ENST00000509979.5
ENST00000513100.5
ENST00000508161.5
ENST00000455559.6
NREP
neuronal regeneration related protein
chr17_+_73232400 0.85 ENST00000535032.7
ENST00000577615.5
ENST00000585109.5
C17orf80
chromosome 17 open reading frame 80
chr15_+_43800586 0.83 ENST00000442995.4
ENST00000458412.2
HYPK
huntingtin interacting protein K
chr17_+_44957907 0.80 ENST00000678938.1
NMT1
N-myristoyltransferase 1
chr5_+_98773651 0.80 ENST00000513185.3
RGMB
repulsive guidance molecule BMP co-receptor b
chr7_+_123601836 0.79 ENST00000434204.5
ASB15
ankyrin repeat and SOCS box containing 15
chr11_+_108116688 0.79 ENST00000672284.1
ACAT1
acetyl-CoA acetyltransferase 1
chr7_+_90709816 0.79 ENST00000436577.3
CDK14
cyclin dependent kinase 14
chr1_+_14929734 0.79 ENST00000376028.8
ENST00000400798.6
KAZN
kazrin, periplakin interacting protein
chr7_+_123601815 0.78 ENST00000451215.6
ASB15
ankyrin repeat and SOCS box containing 15
chr3_-_27722699 0.77 ENST00000461503.2
EOMES
eomesodermin
chr14_-_75069478 0.77 ENST00000555463.1
ACYP1
acylphosphatase 1
chr2_+_149038685 0.75 ENST00000409642.8
ENST00000409876.5
LYPD6B
LY6/PLAUR domain containing 6B
chr4_+_48483324 0.74 ENST00000273861.5
SLC10A4
solute carrier family 10 member 4
chr11_-_57712205 0.73 ENST00000337672.9
ENST00000431606.4
MED19
mediator complex subunit 19
chr7_+_90709231 0.72 ENST00000446790.5
ENST00000265741.7
CDK14
cyclin dependent kinase 14
chr7_+_114416286 0.67 ENST00000635534.1
FOXP2
forkhead box P2
chr16_+_53099100 0.65 ENST00000565832.5
CHD9
chromodomain helicase DNA binding protein 9
chr20_-_35742207 0.65 ENST00000397370.3
ENST00000528062.7
ENST00000374038.7
ENST00000253363.11
ENST00000361162.10
RBM39
RNA binding motif protein 39
chr5_+_140827950 0.61 ENST00000378126.4
ENST00000529310.6
ENST00000527624.1
PCDHA6
protocadherin alpha 6
chr4_+_94995919 0.60 ENST00000509540.6
BMPR1B
bone morphogenetic protein receptor type 1B
chr17_-_41140487 0.60 ENST00000345847.4
KRTAP4-6
keratin associated protein 4-6
chr11_+_57712574 0.59 ENST00000278422.9
ENST00000378312.8
TMX2
thioredoxin related transmembrane protein 2
chr3_-_191282383 0.58 ENST00000427544.6
UTS2B
urotensin 2B
chr12_-_52553139 0.56 ENST00000267119.6
KRT71
keratin 71
chr6_+_112236806 0.55 ENST00000588837.5
ENST00000590293.5
ENST00000585450.5
ENST00000629766.2
ENST00000590804.5
ENST00000590584.4
ENST00000628122.2
ENST00000627025.1
ENST00000590673.5
ENST00000585611.5
ENST00000587816.2
LAMA4-AS1
ENSG00000281613.2
LAMA4 antisense RNA 1
novel ret finger protein-like 4B
chr16_+_68085420 0.54 ENST00000349223.9
NFATC3
nuclear factor of activated T cells 3
chr19_+_49513353 0.54 ENST00000596975.5
FCGRT
Fc fragment of IgG receptor and transporter
chr1_+_174964750 0.53 ENST00000367688.3
RABGAP1L
RAB GTPase activating protein 1 like
chrX_-_15314543 0.52 ENST00000344384.8
ASB11
ankyrin repeat and SOCS box containing 11
chr16_+_68085344 0.52 ENST00000575270.5
ENST00000346183.8
NFATC3
nuclear factor of activated T cells 3
chr3_-_11582330 0.52 ENST00000451674.6
VGLL4
vestigial like family member 4
chr17_+_73232637 0.51 ENST00000268942.12
ENST00000426147.6
C17orf80
chromosome 17 open reading frame 80
chr10_-_101229449 0.51 ENST00000370193.4
LBX1
ladybird homeobox 1
chr3_-_12545499 0.51 ENST00000564146.4
MKRN2OS
MKRN2 opposite strand
chr17_+_58166982 0.50 ENST00000545221.2
OR4D2
olfactory receptor family 4 subfamily D member 2
chr6_+_3258888 0.50 ENST00000380305.4
PSMG4
proteasome assembly chaperone 4
chr1_-_169734064 0.50 ENST00000333360.12
SELE
selectin E
chr9_+_2159850 0.50 ENST00000416751.2
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr15_+_44427591 0.49 ENST00000558791.5
ENST00000260327.9
CTDSPL2
CTD small phosphatase like 2
chr11_-_40294089 0.49 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chr19_-_11346228 0.48 ENST00000588560.5
ENST00000592952.5
TMEM205
transmembrane protein 205
chr17_+_46511511 0.48 ENST00000576629.5
LRRC37A2
leucine rich repeat containing 37 member A2
chr19_-_11346196 0.45 ENST00000586218.5
TMEM205
transmembrane protein 205
chrX_+_109535775 0.44 ENST00000218004.5
NXT2
nuclear transport factor 2 like export factor 2
chr9_+_2159672 0.44 ENST00000634343.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr3_+_154121366 0.43 ENST00000465093.6
ENST00000496710.5
ENST00000465817.1
ARHGEF26
Rho guanine nucleotide exchange factor 26
chr15_+_44427793 0.42 ENST00000558966.5
ENST00000559793.5
ENST00000558968.1
CTDSPL2
CTD small phosphatase like 2
chr12_-_91179355 0.42 ENST00000550563.5
ENST00000546370.5
DCN
decorin
chr1_-_165445220 0.42 ENST00000619224.1
RXRG
retinoid X receptor gamma
chrX_-_130268883 0.42 ENST00000447817.1
ENST00000370978.9
ZNF280C
zinc finger protein 280C
chr1_-_165445088 0.40 ENST00000359842.10
RXRG
retinoid X receptor gamma
chr20_+_33562365 0.40 ENST00000346541.7
ENST00000397800.5
ENST00000492345.5
CBFA2T2
CBFA2/RUNX1 partner transcriptional co-repressor 2
chr15_+_57219411 0.40 ENST00000543579.5
ENST00000537840.5
ENST00000343827.7
TCF12
transcription factor 12
chr1_+_207325629 0.39 ENST00000618707.2
CD55
CD55 molecule (Cromer blood group)
chr3_-_197573323 0.39 ENST00000358186.6
ENST00000431056.5
BDH1
3-hydroxybutyrate dehydrogenase 1
chr20_-_18413216 0.39 ENST00000480488.2
DZANK1
double zinc ribbon and ankyrin repeat domains 1
chr3_-_186544377 0.39 ENST00000307944.6
CRYGS
crystallin gamma S
chr3_+_156142962 0.38 ENST00000471742.5
KCNAB1
potassium voltage-gated channel subfamily A member regulatory beta subunit 1
chr16_+_68085552 0.38 ENST00000329524.8
NFATC3
nuclear factor of activated T cells 3
chr7_-_25228485 0.37 ENST00000222674.2
NPVF
neuropeptide VF precursor
chr3_+_149474688 0.37 ENST00000305354.5
ENST00000465758.1
TM4SF4
transmembrane 4 L six family member 4
chr2_-_201739205 0.37 ENST00000681558.1
ENST00000681495.1
ALS2
alsin Rho guanine nucleotide exchange factor ALS2
chr11_+_55262152 0.36 ENST00000417545.5
TRIM48
tripartite motif containing 48
chr2_+_108621260 0.35 ENST00000409441.5
LIMS1
LIM zinc finger domain containing 1
chr9_+_101398841 0.33 ENST00000339664.7
ENST00000374861.7
ENST00000259395.4
ENST00000615466.1
ZNF189
zinc finger protein 189
chr1_+_42380772 0.33 ENST00000431473.4
ENST00000410070.6
RIMKLA
ribosomal modification protein rimK like family member A
chr7_-_93148345 0.32 ENST00000437805.5
ENST00000446959.5
ENST00000439952.5
ENST00000414791.5
ENST00000446033.1
ENST00000411955.5
ENST00000318238.9
SAMD9L
sterile alpha motif domain containing 9 like
chr11_-_124320197 0.31 ENST00000624618.2
OR8D2
olfactory receptor family 8 subfamily D member 2
chr14_-_37595224 0.31 ENST00000250448.5
FOXA1
forkhead box A1
chrY_-_6874027 0.31 ENST00000215479.10
AMELY
amelogenin Y-linked
chr4_+_112647059 0.30 ENST00000511529.1
LARP7
La ribonucleoprotein 7, transcriptional regulator
chr5_-_161546708 0.30 ENST00000393959.6
GABRB2
gamma-aminobutyric acid type A receptor subunit beta2
chr16_+_24537693 0.29 ENST00000564314.5
ENST00000567686.5
RBBP6
RB binding protein 6, ubiquitin ligase
chr5_-_60488055 0.29 ENST00000505507.6
ENST00000515835.2
ENST00000502484.6
PDE4D
phosphodiesterase 4D
chr5_+_173918186 0.29 ENST00000657000.1
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr4_+_70028452 0.28 ENST00000530128.5
ENST00000381057.3
ENST00000673563.1
HTN3
histatin 3
chr11_-_4288083 0.28 ENST00000638166.1
SSU72P4
SSU72 pseudogene 4
chr1_+_248508073 0.28 ENST00000641804.1
OR2G6
olfactory receptor family 2 subfamily G member 6
chr4_+_159267737 0.27 ENST00000264431.8
RAPGEF2
Rap guanine nucleotide exchange factor 2
chr8_-_56211257 0.27 ENST00000316981.8
ENST00000423799.6
ENST00000429357.2
PLAG1
PLAG1 zinc finger
chr16_-_69339493 0.26 ENST00000562595.5
ENST00000615447.1
ENST00000306875.10
ENST00000562081.2
COG8
component of oligomeric golgi complex 8
chr13_+_53028806 0.26 ENST00000219022.3
OLFM4
olfactomedin 4
chr13_-_94479671 0.26 ENST00000377028.10
ENST00000446125.1
DCT
dopachrome tautomerase
chr9_+_123033660 0.26 ENST00000616002.3
GPR21
G protein-coupled receptor 21
chrX_+_69616067 0.26 ENST00000338901.4
ENST00000525810.5
ENST00000527388.5
ENST00000374553.6
ENST00000374552.9
ENST00000524573.5
EDA
ectodysplasin A
chr2_+_10368764 0.26 ENST00000620771.4
HPCAL1
hippocalcin like 1
chr21_-_14210948 0.25 ENST00000681601.1
LIPI
lipase I
chr7_-_7535863 0.25 ENST00000399429.8
COL28A1
collagen type XXVIII alpha 1 chain
chr2_-_58241259 0.25 ENST00000481670.2
ENST00000403676.5
ENST00000427708.6
ENST00000403295.7
ENST00000233741.9
ENST00000446381.5
ENST00000417361.1
ENST00000402135.7
ENST00000449070.5
FANCL
FA complementation group L
chr3_-_158106408 0.25 ENST00000483851.7
SHOX2
short stature homeobox 2
chr3_+_2892199 0.24 ENST00000397459.6
CNTN4
contactin 4
chr15_+_48191648 0.24 ENST00000646012.1
ENST00000561127.5
ENST00000647546.1
ENST00000559641.5
ENST00000417307.3
SLC12A1
CTXN2
solute carrier family 12 member 1
cortexin 2
chr5_-_67196791 0.23 ENST00000256447.5
CD180
CD180 molecule
chr21_-_14210884 0.23 ENST00000679868.1
ENST00000400211.3
ENST00000680801.1
ENST00000536861.6
ENST00000614229.5
LIPI
lipase I
chr6_-_136550407 0.23 ENST00000354570.8
MAP7
microtubule associated protein 7
chr6_-_41071825 0.22 ENST00000468811.5
OARD1
O-acyl-ADP-ribose deacylase 1
chr3_-_146528750 0.22 ENST00000483300.5
PLSCR1
phospholipid scramblase 1
chr2_+_10368645 0.21 ENST00000613496.4
HPCAL1
hippocalcin like 1
chr12_-_118359105 0.19 ENST00000541186.5
ENST00000539872.5
TAOK3
TAO kinase 3
chr3_-_9249623 0.18 ENST00000383836.8
SRGAP3
SLIT-ROBO Rho GTPase activating protein 3
chr11_+_5351508 0.17 ENST00000380219.1
OR51B6
olfactory receptor family 51 subfamily B member 6
chr17_-_41149823 0.17 ENST00000343246.6
KRTAP4-5
keratin associated protein 4-5
chr3_+_111978996 0.16 ENST00000273359.8
ENST00000494817.1
ABHD10
abhydrolase domain containing 10, depalmitoylase
chr2_+_36696686 0.16 ENST00000379242.7
ENST00000389975.7
VIT
vitrin
chr5_-_77638713 0.15 ENST00000306422.5
OTP
orthopedia homeobox
chr1_+_151254709 0.15 ENST00000368881.8
ENST00000368884.8
PSMD4
proteasome 26S subunit, non-ATPase 4
chr3_+_46354072 0.15 ENST00000445132.3
ENST00000421659.1
CCR2
C-C motif chemokine receptor 2
chr3_-_18438767 0.15 ENST00000454909.6
SATB1
SATB homeobox 1
chr1_-_219613069 0.15 ENST00000367211.6
ENST00000651890.1
ZC3H11B
zinc finger CCCH-type containing 11B
chr11_-_95910665 0.14 ENST00000674610.1
ENST00000675660.1
MTMR2
myotubularin related protein 2
chr12_+_19205294 0.14 ENST00000424268.5
PLEKHA5
pleckstrin homology domain containing A5
chr13_-_40982880 0.14 ENST00000635415.1
ELF1
E74 like ETS transcription factor 1
chr11_-_95910748 0.13 ENST00000675933.1
MTMR2
myotubularin related protein 2
chr8_-_81483226 0.12 ENST00000256104.5
FABP4
fatty acid binding protein 4
chr14_+_22516273 0.12 ENST00000390510.1
TRAJ27
T cell receptor alpha joining 27
chr8_-_20183090 0.12 ENST00000265808.11
ENST00000522513.5
SLC18A1
solute carrier family 18 member A1
chr5_-_116536458 0.12 ENST00000510263.5
SEMA6A
semaphorin 6A
chr16_+_86566821 0.12 ENST00000649859.1
FOXC2
forkhead box C2
chr1_-_50423431 0.12 ENST00000404795.4
DMRTA2
DMRT like family A2
chr5_-_161546671 0.11 ENST00000517547.5
GABRB2
gamma-aminobutyric acid type A receptor subunit beta2
chr14_+_20110739 0.11 ENST00000641386.2
ENST00000641633.2
OR4K17
olfactory receptor family 4 subfamily K member 17
chr17_-_29005913 0.10 ENST00000442608.7
ENST00000317338.17
ENST00000335960.10
SEZ6
seizure related 6 homolog
chr11_+_55635113 0.10 ENST00000641760.1
OR4P4
olfactory receptor family 4 subfamily P member 4
chr8_-_20183127 0.10 ENST00000276373.10
ENST00000519026.5
ENST00000440926.3
ENST00000437980.3
SLC18A1
solute carrier family 18 member A1
chr4_+_164877164 0.09 ENST00000507152.6
ENST00000515275.1
APELA
apelin receptor early endogenous ligand
chr9_+_65700287 0.09 ENST00000489273.1
CBWD5
COBW domain containing 5
chr7_+_148590760 0.09 ENST00000307003.3
C7orf33
chromosome 7 open reading frame 33
chrX_+_101623121 0.08 ENST00000491568.6
ENST00000479298.5
ENST00000471229.7
ARMCX3
armadillo repeat containing X-linked 3
chr8_-_17895487 0.08 ENST00000427924.5
ENST00000381841.4
FGL1
fibrinogen like 1
chr6_-_69699124 0.07 ENST00000651675.1
LMBRD1
LMBR1 domain containing 1
chr8_-_17895403 0.07 ENST00000381840.5
ENST00000398054.5
FGL1
fibrinogen like 1
chr11_+_85648018 0.07 ENST00000532180.1
TMEM126A
transmembrane protein 126A
chr17_-_40755328 0.06 ENST00000312150.5
KRT25
keratin 25
chr3_-_157160751 0.06 ENST00000461804.5
CCNL1
cyclin L1
chr11_-_102705737 0.06 ENST00000260229.5
MMP27
matrix metallopeptidase 27
chr12_+_102957666 0.05 ENST00000266744.4
ASCL1
achaete-scute family bHLH transcription factor 1
chr9_-_27005659 0.05 ENST00000380055.6
LRRC19
leucine rich repeat containing 19

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 12.9 GO:0010430 fatty acid omega-oxidation(GO:0010430)
3.0 12.2 GO:1900228 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.7 2.6 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.6 4.5 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.6 1.9 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.6 1.7 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.5 1.5 GO:0003099 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.5 1.4 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.4 1.8 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.4 6.1 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.3 1.0 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.3 1.5 GO:0021764 amygdala development(GO:0021764)
0.3 0.8 GO:0072019 proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.2 0.7 GO:0021757 caudate nucleus development(GO:0021757) putamen development(GO:0021758)
0.2 2.2 GO:0009449 glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.2 0.8 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.2 1.6 GO:0070294 renal sodium ion absorption(GO:0070294)
0.2 0.5 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.1 2.9 GO:0006228 UTP biosynthetic process(GO:0006228)
0.1 0.3 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.1 0.4 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 1.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.3 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1 2.9 GO:0045332 phospholipid translocation(GO:0045332)
0.1 1.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.4 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.1 1.4 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 5.0 GO:0035082 axoneme assembly(GO:0035082)
0.1 0.3 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1 0.4 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.1 2.3 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 1.4 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.1 3.2 GO:0010107 potassium ion import(GO:0010107)
0.1 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 4.0 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:0002434 immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) negative regulation of eosinophil activation(GO:1902567) positive regulation of monocyte extravasation(GO:2000439)
0.0 1.3 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 1.8 GO:0010842 retina layer formation(GO:0010842)
0.0 1.8 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0072144 positive regulation of vascular wound healing(GO:0035470) glomerular mesangial cell development(GO:0072144)
0.0 0.2 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.0 0.5 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.6 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.4 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.0 0.2 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.1 GO:0090133 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.0 0.3 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 1.0 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.3 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 3.2 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0 0.0 GO:2000405 negative regulation of T cell migration(GO:2000405)
0.0 0.9 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.3 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.0 1.1 GO:0030220 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.0 0.2 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.6 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.3 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.0 0.7 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.3 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.5 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.8 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 1.1 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 1.5 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.2 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.3 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.0 GO:0071284 epinephrine metabolic process(GO:0042414) copper ion export(GO:0060003) cellular response to lead ion(GO:0071284)
0.0 0.2 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.4 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.4 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.1 GO:0038016 insulin receptor internalization(GO:0038016)
0.0 0.1 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 1.2 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 3.2 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.0 0.7 GO:0099601 regulation of neurotransmitter receptor activity(GO:0099601)
0.0 0.0 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.0 1.3 GO:0006289 nucleotide-excision repair(GO:0006289)
0.0 0.4 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 0.2 GO:0007158 neuron cell-cell adhesion(GO:0007158)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0097545 radial spoke(GO:0001534) axonemal outer doublet(GO:0097545)
0.4 2.6 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.4 2.8 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.3 4.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.2 1.0 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 1.3 GO:0000439 core TFIIH complex(GO:0000439)
0.1 1.7 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 1.8 GO:0043194 axon initial segment(GO:0043194)
0.1 2.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 1.0 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.4 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.9 GO:0071564 npBAF complex(GO:0071564)
0.0 3.7 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.2 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.8 GO:0030057 desmosome(GO:0030057)
0.0 3.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.9 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 2.0 GO:0005901 caveola(GO:0005901)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 3.3 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.0 1.2 GO:0045095 keratin filament(GO:0045095)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.4 GO:0098576 lumenal side of membrane(GO:0098576)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 12.9 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.5 1.5 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.5 1.4 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.4 4.5 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.4 3.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.3 1.6 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.3 1.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.2 2.6 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.2 0.8 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.2 0.8 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.2 0.8 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.2 3.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 2.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.2 3.3 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.7 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.5 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.4 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 0.8 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 0.3 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
0.1 2.9 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 0.2 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 2.9 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 1.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.3 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.1 1.6 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 2.8 GO:0030332 cyclin binding(GO:0030332)
0.1 0.7 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 1.7 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 1.2 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.1 0.2 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.1 0.3 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 1.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.4 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.5 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.4 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0 0.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 1.0 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 1.8 GO:0030507 spectrin binding(GO:0030507)
0.0 0.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 1.0 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 1.0 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 1.3 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 2.3 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.0 GO:0043682 copper-exporting ATPase activity(GO:0004008) phosphoglycerate kinase activity(GO:0004618) copper-transporting ATPase activity(GO:0043682)
0.0 0.0 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.4 GO:0070402 NADPH binding(GO:0070402)
0.0 0.9 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 1.5 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.8 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.2 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.3 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.3 PID BMP PATHWAY BMP receptor signaling
0.1 1.4 PID IL5 PATHWAY IL5-mediated signaling events
0.0 3.4 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 3.8 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.6 PID INSULIN PATHWAY Insulin Pathway
0.0 1.3 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 3.3 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.8 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.1 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 4.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.2 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.8 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.4 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.5 PID ATF2 PATHWAY ATF-2 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 12.9 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 4.0 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 4.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 2.9 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 1.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 3.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 3.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.1 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.8 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.1 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 1.9 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 1.3 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.8 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.7 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.8 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation