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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for DUXA

Z-value: 0.88

Motif logo

Transcription factors associated with DUXA

Gene Symbol Gene ID Gene Info
ENSG00000258873.3 DUXA

Activity profile of DUXA motif

Sorted Z-values of DUXA motif

Network of associatons between targets according to the STRING database.

First level regulatory network of DUXA

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr19_-_50968125 5.53 ENST00000594641.1
kallikrein related peptidase 6
chr19_-_50968775 4.15 ENST00000391808.5
kallikrein related peptidase 6
chr4_+_68447453 3.55 ENST00000305363.9
transmembrane serine protease 11E
chr8_-_7781413 3.49 ENST00000528972.1
proline rich 23 domain containing 2
chr8_+_7539627 3.44 ENST00000533250.2
proline rich 23 domain containing 1
chr12_-_57237090 2.56 ENST00000556732.1
NDUFA4 mitochondrial complex associated like 2
chr2_+_227813834 2.35 ENST00000358813.5
ENST00000409189.7
C-C motif chemokine ligand 20
chr22_+_31082860 2.32 ENST00000619644.4
smoothelin
chr11_-_89920428 2.26 ENST00000605881.5
tripartite motif containing 49D1
chr1_+_17249088 2.20 ENST00000375460.3
peptidyl arginine deiminase 3
chr15_+_41286011 2.08 ENST00000661438.1
novel protein
chr18_+_63777773 2.06 ENST00000447428.5
ENST00000546027.5
serpin family B member 7
chr11_-_48983826 1.95 ENST00000649162.1
tripartite motif-containing 51G, pseudogene
chr7_-_99679987 1.79 ENST00000222982.8
ENST00000439761.3
ENST00000339843.6
cytochrome P450 family 3 subfamily A member 5
chr2_+_233691607 1.78 ENST00000373424.5
ENST00000441351.1
UDP glucuronosyltransferase family 1 member A6
chr1_+_12773738 1.76 ENST00000357726.5
PRAME family member 12
chr17_-_41397600 1.75 ENST00000251645.3
keratin 31
chr11_+_89924064 1.71 ENST00000623787.3
tripartite motif containing 49D2
chr11_-_28108109 1.68 ENST00000263181.7
kinesin family member 18A
chr6_-_150025520 1.58 ENST00000367341.6
ENST00000286380.2
retinoic acid early transcript 1L
chr8_-_124565699 1.46 ENST00000519168.5
MTSS I-BAR domain containing 1
chr1_+_13068677 1.41 ENST00000614839.4
PRAME family member 25
chr15_-_79971164 1.40 ENST00000335661.6
ENST00000267953.4
ENST00000677151.1
BCL2 related protein A1
chr2_-_208129824 1.37 ENST00000282141.4
crystallin gamma C
chr19_-_7058640 1.35 ENST00000333843.8
methyl-CpG binding domain protein 3 like 3
chr3_-_139539577 1.33 ENST00000619087.4
retinol binding protein 1
chr19_+_7030578 1.32 ENST00000329753.5
methyl-CpG binding domain protein 3 like 5
chr14_+_20469399 1.31 ENST00000361505.10
ENST00000553591.1
purine nucleoside phosphorylase
chr10_+_76318330 1.31 ENST00000496424.2
leucine rich melanocyte differentiation associated
chr20_+_23491090 1.30 ENST00000449810.5
ENST00000246012.2
cystatin 8
chr19_-_7021431 1.28 ENST00000636986.2
ENST00000637800.1
methyl-CpG binding domain protein 3 like 2B
chr14_+_23630109 1.28 ENST00000432832.6
dehydrogenase/reductase 2
chr7_+_124476371 1.28 ENST00000473520.1
SSU72 pseudogene 8
chr12_-_6635938 1.26 ENST00000329858.9
lysophosphatidic acid receptor 5
chr1_-_110390989 1.23 ENST00000369779.9
ENST00000472422.6
solute carrier family 16 member 4
chr19_+_7049321 1.18 ENST00000381393.3
methyl-CpG binding domain protein 3 like 2
chr6_+_121437378 1.18 ENST00000650427.1
ENST00000647564.1
gap junction protein alpha 1
chr14_-_63318933 1.15 ENST00000621500.2
glycoprotein hormone subunit beta 5
chr6_+_54018992 1.10 ENST00000509997.5
muscular LMNA interacting protein
chr10_+_11823348 1.08 ENST00000277570.10
ENST00000622831.4
proline and serine rich 2
chr1_-_110391041 1.06 ENST00000369781.8
ENST00000437429.6
ENST00000541986.5
solute carrier family 16 member 4
chr9_+_72577369 1.06 ENST00000651183.1
transmembrane channel like 1
chr12_-_119877300 1.04 ENST00000392521.7
citron rho-interacting serine/threonine kinase
chr19_-_7040179 1.04 ENST00000381394.9
methyl-CpG binding domain protein 3 like 4
chr12_-_119877270 1.03 ENST00000261833.11
ENST00000612548.4
citron rho-interacting serine/threonine kinase
chr4_+_147732070 1.01 ENST00000336498.8
Rho GTPase activating protein 10
chr7_+_141790217 1.00 ENST00000247883.5
taste 2 receptor member 5
chr2_-_40453438 0.93 ENST00000455476.5
solute carrier family 8 member A1
chr8_-_90082871 0.92 ENST00000265431.7
calbindin 1
chr19_-_6393205 0.92 ENST00000595047.5
general transcription factor IIF subunit 1
chr2_-_55334529 0.91 ENST00000645860.1
ENST00000642563.1
ENST00000647396.1
coiled-coil domain containing 88A
chr6_-_111567271 0.90 ENST00000464903.1
ENST00000368730.5
ENST00000368735.1
TRAF3 interacting protein 2
chr5_+_151025343 0.89 ENST00000521632.1
glutathione peroxidase 3
chr11_-_4288083 0.89 ENST00000638166.1
SSU72 pseudogene 4
chr13_+_108596152 0.88 ENST00000356711.7
ENST00000251041.10
myosin XVI
chr14_+_22147988 0.88 ENST00000390457.2
T cell receptor alpha variable 27
chrX_+_100666854 0.86 ENST00000640282.1
sushi repeat containing protein X-linked 2
chr6_-_111567120 0.85 ENST00000368734.5
TRAF3 interacting protein 2
chr19_-_6393131 0.84 ENST00000394456.10
general transcription factor IIF subunit 1
chr6_+_31158518 0.83 ENST00000376255.4
ENST00000376257.8
transcription factor 19
chr9_+_34652167 0.82 ENST00000441545.7
ENST00000553620.5
interleukin 11 receptor subunit alpha
chr2_-_174764436 0.76 ENST00000409323.1
ENST00000261007.9
ENST00000348749.9
ENST00000672640.1
cholinergic receptor nicotinic alpha 1 subunit
chr7_-_93890744 0.76 ENST00000650573.1
ENST00000222543.11
ENST00000649913.1
ENST00000647793.1
tissue factor pathway inhibitor 2
chr1_+_13070853 0.75 ENST00000619661.2
PRAME family member 25
chr6_+_54018910 0.71 ENST00000514921.5
ENST00000274897.9
ENST00000370877.6
muscular LMNA interacting protein
chr11_-_4339244 0.71 ENST00000524542.2
SSU72 pseudogene 7
chr1_-_12898270 0.70 ENST00000235347.4
PRAME family member 10
chr11_-_4242640 0.69 ENST00000640805.1
SSU72 pseudogene 2
chr14_-_80231052 0.68 ENST00000557010.5
iodothyronine deiodinase 2
chr13_+_57140918 0.67 ENST00000377931.1
ENST00000614894.4
proline rich 20A
proline rich 20C
chr11_-_89921767 0.66 ENST00000530311.6
tripartite motif containing 49D1
chrX_+_86714623 0.66 ENST00000484479.1
dachshund family transcription factor 2
chr18_+_63887698 0.66 ENST00000457692.5
ENST00000299502.9
ENST00000413956.5
serpin family B member 2
chr1_+_153031195 0.64 ENST00000307098.5
small proline rich protein 1B
chr5_-_113434978 0.64 ENST00000390666.4
testis specific serine kinase 1B
chr1_-_13201409 0.63 ENST00000625019.3
PRAME family member 13
chr11_+_4233288 0.62 ENST00000639584.1
SSU72 pseudogene 5
chr8_+_69466617 0.61 ENST00000525061.5
ENST00000260128.8
ENST00000458141.6
sulfatase 1
chr6_+_36029082 0.60 ENST00000472333.1
mitogen-activated protein kinase 14
chr13_+_57147488 0.59 ENST00000377930.1
proline rich 20B
chr10_-_29634964 0.59 ENST00000375398.6
ENST00000355867.8
supervillin
chr11_+_28108248 0.59 ENST00000406787.7
ENST00000403099.5
ENST00000407364.8
methyltransferase like 15
chr6_-_65707214 0.59 ENST00000370621.7
ENST00000393380.6
ENST00000503581.6
eyes shut homolog
chr13_+_32031706 0.58 ENST00000542859.6
FRY microtubule binding protein
chr1_+_13060769 0.58 ENST00000617807.3
heterogeneous nuclear ribonucleoprotein C like 3
chr3_+_45886501 0.57 ENST00000395963.2
C-C motif chemokine receptor 9
chr4_+_87608529 0.55 ENST00000651931.1
dentin sialophosphoprotein
chr1_-_173824856 0.55 ENST00000682279.1
centromere protein L
chr11_-_13496018 0.55 ENST00000529816.1
parathyroid hormone
chr5_+_154858218 0.54 ENST00000523698.5
ENST00000517876.5
ENST00000520472.5
CCR4-NOT transcription complex subunit 8
chr11_+_114400030 0.53 ENST00000540163.5
RNA binding motif protein 7
chr16_-_21211566 0.53 ENST00000574091.6
zona pellucida glycoprotein 2
chr1_-_12945416 0.53 ENST00000415464.6
PRAME family member 6
chr15_+_66453418 0.53 ENST00000566326.1
mitogen-activated protein kinase kinase 1
chr19_-_14674829 0.53 ENST00000443157.6
ENST00000253673.6
adhesion G protein-coupled receptor E3
chr19_-_14674886 0.52 ENST00000344373.8
ENST00000595472.1
adhesion G protein-coupled receptor E3
chr10_-_110304894 0.52 ENST00000369603.10
survival motor neuron domain containing 1
chr1_-_13116854 0.52 ENST00000621994.3
heterogeneous nuclear ribonucleoprotein C like 2
chr12_+_56128217 0.51 ENST00000267113.4
ENST00000394048.10
extended synaptotagmin 1
chr1_-_12848720 0.51 ENST00000317869.7
heterogeneous nuclear ribonucleoprotein C like 1
chr16_-_15056060 0.51 ENST00000287706.8
ENST00000624579.3
ENST00000622833.4
N-terminal asparagine amidase
chr1_+_13303539 0.50 ENST00000437300.2
PRAME family member 33
chr12_-_10909562 0.50 ENST00000390677.2
taste 2 receptor member 13
chr19_-_46846138 0.49 ENST00000597020.5
adaptor related protein complex 2 subunit sigma 1
chr7_+_93906557 0.48 ENST00000248572.10
ENST00000429473.1
ENST00000430875.1
ENST00000428834.1
G protein subunit gamma transducin 1
chr16_+_29995661 0.47 ENST00000304516.11
INO80 complex subunit E
chr12_-_102480604 0.47 ENST00000392905.7
insulin like growth factor 1
chr12_+_50504970 0.47 ENST00000301180.10
disco interacting protein 2 homolog B
chr2_+_161136901 0.47 ENST00000259075.6
ENST00000432002.5
TRAF family member associated NFKB activator
chr1_+_13171848 0.47 ENST00000415919.3
PRAME family member 9
chr17_-_10373002 0.47 ENST00000252172.9
ENST00000418404.8
myosin heavy chain 13
chr1_-_12886201 0.47 ENST00000235349.6
PRAME family member 4
chr16_-_15055969 0.47 ENST00000566419.1
ENST00000568320.5
N-terminal asparagine amidase
chr9_-_92878018 0.47 ENST00000332591.6
ENST00000375495.8
ENST00000395505.6
ENST00000395506.7
zinc finger protein 484
chr6_-_49636832 0.46 ENST00000371175.10
ENST00000646272.1
ENST00000646939.1
ENST00000618248.3
ENST00000229810.9
ENST00000646963.1
Rh associated glycoprotein
chrX_+_37780049 0.46 ENST00000378588.5
cytochrome b-245 beta chain
chr8_+_52939182 0.46 ENST00000674939.1
neuropeptides B and W receptor 1
chr11_+_68903849 0.45 ENST00000675615.1
ENST00000255078.8
immunoglobulin mu DNA binding protein 2
chr12_+_12725897 0.45 ENST00000326765.10
apolipoprotein L domain containing 1
chr2_+_201129483 0.45 ENST00000440180.5
CASP8 and FADD like apoptosis regulator
chr3_-_196270540 0.44 ENST00000419333.5
phosphate cytidylyltransferase 1, choline, alpha
chr15_+_45252228 0.44 ENST00000560438.5
ENST00000347644.8
solute carrier family 28 member 2
chr6_+_31971831 0.44 ENST00000375331.7
ENST00000375333.3
serine/threonine kinase 19
chr9_-_27005659 0.43 ENST00000380055.6
leucine rich repeat containing 19
chr13_+_97953652 0.43 ENST00000460070.6
ENST00000481455.6
ENST00000261574.10
ENST00000651721.2
ENST00000493281.6
ENST00000463157.6
ENST00000471898.5
ENST00000489058.6
ENST00000481689.6
importin 5
chr11_+_95790459 0.43 ENST00000325486.9
ENST00000325542.10
ENST00000544522.5
ENST00000541365.5
centrosomal protein 57
chr5_+_150497772 0.42 ENST00000523767.5
N-deacetylase and N-sulfotransferase 1
chr8_-_48921419 0.42 ENST00000020945.4
snail family transcriptional repressor 2
chrX_+_77910656 0.41 ENST00000343533.9
ENST00000341514.11
ENST00000645454.1
ENST00000642651.1
ENST00000644362.1
ATPase copper transporting alpha
phosphoglycerate kinase 1
chr1_+_13254212 0.41 ENST00000622421.2
PRAME family member 5
chr1_+_13061158 0.40 ENST00000681473.1
heterogeneous nuclear ribonucleoprotein C like 3
chr16_-_89719369 0.40 ENST00000561976.5
VPS9 domain containing 1
chr1_-_13165631 0.40 ENST00000323770.8
heterogeneous nuclear ribonucleoprotein C like 4
chr6_+_168017873 0.39 ENST00000351261.4
ENST00000354419.6
kinesin family member 25
chr3_+_160225409 0.38 ENST00000326474.5
chromosome 3 open reading frame 80
chr1_+_95151377 0.38 ENST00000604203.1
TLCD4-RWDD3 readthrough
chr13_+_57154061 0.37 ENST00000544357.2
proline rich 20C
chr13_+_57160632 0.37 ENST00000452123.3
proline rich 20D
chr13_+_57167197 0.37 ENST00000434815.1
proline rich 20E
chr1_-_116667668 0.37 ENST00000369486.8
ENST00000369483.5
immunoglobulin superfamily member 3
chr4_-_8428424 0.37 ENST00000514423.1
ENST00000503233.5
acyl-CoA oxidase 3, pristanoyl
chr11_-_11353241 0.37 ENST00000528848.3
casein kinase 2 alpha 3
chr16_+_6483728 0.37 ENST00000675459.1
ENST00000551752.5
RNA binding fox-1 homolog 1
chr17_+_36486668 0.37 ENST00000617429.5
ENST00000620324.4
ENST00000616269.1
zinc finger HIT-type containing 3
chr16_+_29996201 0.36 ENST00000620599.4
ENST00000563197.6
ENST00000567254.5
ENST00000567705.5
INO80 complex subunit E
chr6_-_138499487 0.36 ENST00000343505.9
NHS like 1
chr8_-_7486400 0.36 ENST00000335479.2
defensin beta 106B
chr5_-_16916400 0.36 ENST00000513882.5
myosin X
chr12_-_122730828 0.36 ENST00000432564.3
hydroxycarboxylic acid receptor 1
chr2_-_68871382 0.36 ENST00000295379.2
bone morphogenetic protein 10
chr3_-_71360753 0.36 ENST00000648783.1
forkhead box P1
chr20_-_17558811 0.35 ENST00000536626.7
ENST00000377868.6
beaded filament structural protein 1
chr14_-_54441325 0.35 ENST00000556113.1
ENST00000553660.5
ENST00000216416.9
ENST00000395573.8
ENST00000557690.5
cornichon family AMPA receptor auxiliary protein 1
chr8_+_7825137 0.35 ENST00000335186.3
defensin beta 106A
chr2_-_174764407 0.35 ENST00000409219.5
ENST00000409542.5
cholinergic receptor nicotinic alpha 1 subunit
chr2_-_200889266 0.35 ENST00000443398.5
ENST00000286175.12
ENST00000409449.5
peptidylprolyl isomerase like 3
chr10_-_32935511 0.35 ENST00000423113.5
integrin subunit beta 1
chr1_+_74235377 0.35 ENST00000326637.8
TNNI3 interacting kinase
chr12_+_18262730 0.34 ENST00000675017.1
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr2_+_169066994 0.34 ENST00000357546.6
ENST00000432060.6
dehydrogenase/reductase 9
chr12_-_48570046 0.34 ENST00000301046.6
ENST00000549817.1
lactalbumin alpha
chr12_-_48865863 0.34 ENST00000309739.6
Rho family GTPase 1
chr1_-_12947580 0.33 ENST00000376189.5
PRAME family member 6
chr12_-_54259531 0.33 ENST00000550411.5
ENST00000439541.6
chromobox 5
chr12_+_8513499 0.33 ENST00000299665.3
C-type lectin domain family 4 member D
chr8_-_17002327 0.33 ENST00000180166.6
fibroblast growth factor 20
chr11_+_56176618 0.33 ENST00000312298.1
olfactory receptor family 5 subfamily J member 2
chr3_-_128467248 0.33 ENST00000319153.3
DnaJ heat shock protein family (Hsp40) member B8
chr2_-_200889136 0.32 ENST00000409361.5
peptidylprolyl isomerase like 3
chr3_-_125055987 0.32 ENST00000311127.9
heart development protein with EGF like domains 1
chr5_-_78294656 0.32 ENST00000519295.5
ENST00000255194.11
adaptor related protein complex 3 subunit beta 1
chr2_+_196713117 0.32 ENST00000409270.5
coiled-coil domain containing 150
chr5_-_79514127 0.32 ENST00000334082.11
homer scaffold protein 1
chr6_+_167291329 0.32 ENST00000366829.2
unc-93 homolog A
chr2_-_200888993 0.31 ENST00000409264.6
ENST00000392283.9
peptidylprolyl isomerase like 3
chr12_-_118190510 0.31 ENST00000540561.5
ENST00000537952.1
ENST00000537822.1
TAO kinase 3
chrX_+_38006551 0.31 ENST00000297875.7
synaptotagmin like 5
chr6_+_167291309 0.30 ENST00000230256.8
unc-93 homolog A
chrX_+_23667461 0.30 ENST00000379341.9
ENST00000379331.3
peroxiredoxin 4
chr16_+_6483813 0.30 ENST00000675653.1
RNA binding fox-1 homolog 1
chr3_-_114199407 0.30 ENST00000460779.5
dopamine receptor D3
chr12_-_91153149 0.30 ENST00000550758.1
decorin
chr5_-_181238195 0.30 ENST00000509148.1
receptor for activated C kinase 1
chr1_+_13315581 0.29 ENST00000376152.2
PRAME family member 15
chr17_+_36486629 0.29 ENST00000619730.4
zinc finger HIT-type containing 3
chr1_+_224356852 0.29 ENST00000366858.7
ENST00000366857.9
ENST00000465271.6
ENST00000366856.3
cornichon family AMPA receptor auxiliary protein 4
chr20_-_45670239 0.28 ENST00000324384.4
ENST00000356562.6
WAP four-disulfide core domain 11
chr2_+_159733958 0.28 ENST00000409591.5
membrane associated ring-CH-type finger 7
chr3_-_196515315 0.28 ENST00000397537.3
single-pass membrane protein with coiled-coil domains 1
chr9_-_92536031 0.28 ENST00000344604.9
ENST00000375540.5
extracellular matrix protein 2
chr12_+_8509460 0.28 ENST00000382064.6
C-type lectin domain family 4 member D
chr4_+_55853639 0.28 ENST00000381295.7
ENST00000346134.11
ENST00000349598.6
exocyst complex component 1
chr12_-_118359639 0.27 ENST00000541786.5
ENST00000419821.6
ENST00000541878.5
TAO kinase 3
chr3_-_177196451 0.27 ENST00000430069.5
ENST00000630796.2
ENST00000428970.5
TBL1X receptor 1
chr19_+_52429181 0.27 ENST00000301085.8
zinc finger protein 534
chr4_+_146175702 0.27 ENST00000296581.11
ENST00000649747.1
ENST00000502781.5
LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated
chr6_+_26199509 0.27 ENST00000356530.5
H2B clustered histone 7
chr16_+_57186281 0.27 ENST00000564435.5
ENST00000562959.1
ENST00000568505.6
ENST00000394420.9
ENST00000537866.5
ring finger and SPRY domain containing 1
chr11_-_73761051 0.26 ENST00000336083.8
ENST00000536566.5
ENST00000541588.5
ENST00000540771.5
ENST00000310653.10
RAB6A, member RAS oncogene family
chr6_+_29170907 0.26 ENST00000641417.1
olfactory receptor family 2 subfamily J member 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.5 2.2 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.5 9.7 GO:0016540 protein autoprocessing(GO:0016540)
0.4 1.8 GO:0009822 alkaloid catabolic process(GO:0009822)
0.4 2.1 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.3 1.2 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.3 1.5 GO:0030035 microspike assembly(GO:0030035)
0.2 0.4 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.2 0.6 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.2 0.6 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.2 4.9 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.2 1.3 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.2 0.3 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.2 1.9 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.2 0.5 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.2 0.9 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 0.7 GO:1904075 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.1 0.9 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.1 0.6 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.1 2.0 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 0.5 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.1 0.4 GO:0071284 copper ion export(GO:0060003) cellular response to lead ion(GO:0071284)
0.1 0.4 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.1 0.5 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 0.3 GO:0005989 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.1 0.5 GO:0007343 egg activation(GO:0007343)
0.1 1.1 GO:0060005 vestibular reflex(GO:0060005)
0.1 1.2 GO:0002155 regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.1 0.6 GO:2001184 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) positive regulation of interleukin-12 secretion(GO:2001184)
0.1 1.7 GO:0002138 retinoic acid biosynthetic process(GO:0002138)
0.1 0.3 GO:0015917 aminophospholipid transport(GO:0015917)
0.1 0.9 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.3 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 0.5 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.9 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.5 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.1 0.3 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 0.3 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416) musculoskeletal movement, spinal reflex action(GO:0050883)
0.1 1.7 GO:0072520 seminiferous tubule development(GO:0072520)
0.1 0.4 GO:0061760 antifungal innate immune response(GO:0061760)
0.1 0.9 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 0.3 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 0.6 GO:0070475 rRNA base methylation(GO:0070475)
0.1 1.3 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1 1.7 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.1 0.3 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.1 0.4 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 3.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 0.2 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.1 0.4 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.0 0.3 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161) regulation of collagen catabolic process(GO:0010710)
0.0 0.2 GO:0043605 cellular amide catabolic process(GO:0043605)
0.0 0.4 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.0 0.2 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.0 0.1 GO:1901674 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.0 0.2 GO:1990168 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.0 0.4 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.7 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.2 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.0 0.2 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 1.3 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.3 GO:0051343 positive regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051343)
0.0 0.4 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.2 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.1 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 1.4 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 1.2 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.3 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.3 GO:0060613 fat pad development(GO:0060613)
0.0 0.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.8 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.1 GO:1903216 regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.0 1.3 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.1 GO:0021763 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.0 0.4 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.4 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.2 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.1 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.4 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.1 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.0 0.3 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.2 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.6 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.7 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.4 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.5 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 0.4 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.1 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 1.6 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.0 0.2 GO:0043587 tongue morphogenesis(GO:0043587)
0.0 2.4 GO:0070268 cornification(GO:0070268)
0.0 0.3 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 1.8 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.5 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.2 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847) negative regulation of osteoclast development(GO:2001205)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0048478 replication fork protection(GO:0048478)
0.0 0.5 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.1 GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
0.0 0.5 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.0 1.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.2 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 1.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.5 GO:0031055 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.0 GO:0048560 establishment of anatomical structure orientation(GO:0048560)
0.0 1.9 GO:0006939 smooth muscle contraction(GO:0006939)
0.0 0.6 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.6 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.1 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.5 GO:0010659 cardiac muscle cell apoptotic process(GO:0010659)
0.0 0.3 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.3 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.2 GO:0003334 keratinocyte development(GO:0003334)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.2 2.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 1.7 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.3 GO:0034677 integrin alpha7-beta1 complex(GO:0034677)
0.1 0.7 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1 0.4 GO:1990742 microvesicle(GO:1990742)
0.1 0.2 GO:0035189 Rb-E2F complex(GO:0035189)
0.1 1.0 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.3 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.1 0.2 GO:1990032 parallel fiber(GO:1990032)
0.1 1.1 GO:0032426 stereocilium tip(GO:0032426)
0.1 0.3 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.6 GO:0036449 microtubule minus-end(GO:0036449)
0.0 1.3 GO:0005916 fascia adherens(GO:0005916)
0.0 0.2 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.9 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.4 GO:0042587 glycogen granule(GO:0042587)
0.0 1.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.3 GO:1990630 IRE1-RACK1-PP2A complex(GO:1990630)
0.0 0.5 GO:0032797 SMN complex(GO:0032797)
0.0 0.8 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.5 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.3 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.3 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.3 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.4 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.5 GO:0030122 AP-2 adaptor complex(GO:0030122) endolysosome membrane(GO:0036020)
0.0 0.5 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 1.7 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 2.6 GO:0005795 Golgi stack(GO:0005795)
0.0 0.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.4 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.6 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.3 GO:0032982 myosin filament(GO:0032982)
0.0 0.1 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.0 GO:0000814 ESCRT II complex(GO:0000814)
0.0 13.2 GO:0030141 secretory granule(GO:0030141)
0.0 0.9 GO:0043195 terminal bouton(GO:0043195)
0.0 0.3 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.5 2.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.3 1.3 GO:0002060 purine nucleobase binding(GO:0002060)
0.3 1.2 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.3 1.3 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.2 0.9 GO:0005499 vitamin D binding(GO:0005499)
0.1 1.2 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.1 0.4 GO:0043682 copper-exporting ATPase activity(GO:0004008) phosphoglycerate kinase activity(GO:0004618) copper-transporting ATPase activity(GO:0043682)
0.1 0.7 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 1.6 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 4.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.6 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.6 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 1.8 GO:0019211 phosphatase activator activity(GO:0019211)
0.1 0.9 GO:0008430 selenium binding(GO:0008430)
0.1 0.4 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.1 0.4 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 0.9 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 0.3 GO:0070052 collagen V binding(GO:0070052)
0.1 0.4 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.4 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 0.3 GO:0004461 lactose synthase activity(GO:0004461)
0.1 0.2 GO:0033142 progesterone receptor binding(GO:0033142)
0.1 0.5 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.5 GO:0032190 acrosin binding(GO:0032190)
0.1 1.1 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 1.7 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 0.4 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.1 2.3 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 1.4 GO:0051400 BH domain binding(GO:0051400)
0.1 1.8 GO:0070330 aromatase activity(GO:0070330)
0.1 0.5 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 1.3 GO:0019841 retinol binding(GO:0019841)
0.1 1.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 1.9 GO:0001972 retinoic acid binding(GO:0001972)
0.1 1.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.2 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.1 0.6 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.2 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.0 0.9 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.2 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.3 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 13.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.7 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.1 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 0.4 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.1 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 1.1 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.8 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.3 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.7 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.3 GO:0031013 troponin I binding(GO:0031013)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.3 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 1.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.9 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.3 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 2.0 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 3.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.5 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 2.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.4 GO:0031433 telethonin binding(GO:0031433)
0.0 0.4 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.6 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 2.1 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.1 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.5 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.5 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.5 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.1 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.3 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.1 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 1.0 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.0 0.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.4 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.7 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.2 GO:1990239 steroid hormone binding(GO:1990239)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.7 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.5 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 3.7 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.3 GO:0004806 triglyceride lipase activity(GO:0004806)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 9.7 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.5 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.6 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.9 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 2.4 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.1 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.7 PID IGF1 PATHWAY IGF1 pathway
0.0 1.5 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.3 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.9 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.3 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 1.8 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 1.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 1.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 1.1 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 1.0 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 1.7 REACTOME KINESINS Genes involved in Kinesins
0.0 3.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.0 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.5 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.5 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 1.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.9 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 1.1 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 0.9 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.8 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.3 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.2 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.1 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.5 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 1.0 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.0 0.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.2 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.1 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis