ISMARA results: E2F2

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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for E2F2_E2F5

Z-value: 2.31

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Transcription factors associated with E2F2_E2F5

Gene Symbol	Gene ID	Gene Info
E2F2 Ensembl NCBI GeneCards UniProt	ENSG00000007968.7	E2F2
E2F5 Ensembl NCBI GeneCards UniProt	ENSG00000133740.11	E2F5

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
E2F2	hg38_v1_chr1_-_23531206_23531241	0.69	2.7e-05	Click!
E2F5	hg38_v1_chr8_+_85209213_85209270	-0.30	1.1e-01	Click!

Activity profile of E2F2_E2F5 motif

Sorted Z-values of E2F2_E2F5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of E2F2_E2F5

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Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr19_+_4909430 Show fit	21.92	ENST00000620565.4 ENST00000613817.4 ENST00000624301.3 ENST00000650932.1	UHRF1 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin like with PHD and ring finger domains 1
chr2_+_10123171 Show fit	18.76	ENST00000615152.5	RRM2 Ensembl NCBI GeneCards UniProt Show fit	ribonucleotide reductase regulatory subunit M2
chr2_+_173354820 Show fit	14.60	ENST00000347703.7 ENST00000410101.7 ENST00000410019.3 ENST00000306721.8	CDCA7 Ensembl NCBI GeneCards UniProt Show fit	cell division cycle associated 7
chr20_+_25407657 Show fit	11.17	ENST00000262460.5	GINS1 Ensembl NCBI GeneCards UniProt Show fit	GINS complex subunit 1
chr2_-_135876382 Show fit	10.73	ENST00000264156.3	MCM6 Ensembl NCBI GeneCards UniProt Show fit	minichromosome maintenance complex component 6
chr1_-_25906457 Show fit	10.55	ENST00000426559.6	STMN1 Ensembl NCBI GeneCards UniProt Show fit	stathmin 1
chr10_+_60778331 Show fit	10.35	ENST00000519078.6 ENST00000316629.8 ENST00000395284.8	CDK1 Ensembl NCBI GeneCards UniProt Show fit	cyclin dependent kinase 1
chr4_+_153344671 Show fit	9.61	ENST00000240488.8	MND1 Ensembl NCBI GeneCards UniProt Show fit	meiotic nuclear divisions 1
chr10_+_60778490 Show fit	9.33	ENST00000448257.6 ENST00000614696.4	CDK1 Ensembl NCBI GeneCards UniProt Show fit	cyclin dependent kinase 1
chr15_-_64381431 Show fit	9.17	ENST00000558008.3 ENST00000300035.9 ENST00000559519.5 ENST00000380258.6	PCLAF Ensembl NCBI GeneCards UniProt Show fit	PCNA clamp associated factor
chr4_+_153344633 Show fit	8.96	ENST00000622785.4	MND1 Ensembl NCBI GeneCards UniProt Show fit	meiotic nuclear divisions 1
chr7_-_100101333 Show fit	8.89	ENST00000303887.10	MCM7 Ensembl NCBI GeneCards UniProt Show fit	minichromosome maintenance complex component 7
chr3_+_127598400 Show fit	8.54	ENST00000265056.12	MCM2 Ensembl NCBI GeneCards UniProt Show fit	minichromosome maintenance complex component 2
chr22_+_35400115 Show fit	8.50	ENST00000382011.9 ENST00000216122.9 ENST00000416905.1	MCM5 Ensembl NCBI GeneCards UniProt Show fit	minichromosome maintenance complex component 5
chr14_-_49688201 Show fit	8.40	ENST00000553805.2 ENST00000554396.5 ENST00000216367.10	POLE2 Ensembl NCBI GeneCards UniProt Show fit	DNA polymerase epsilon 2, accessory subunit
chr1_+_212035717 Show fit	8.39	ENST00000366991.5	DTL Ensembl NCBI GeneCards UniProt Show fit	denticleless E3 ubiquitin protein ligase homolog
chr9_-_96418334 Show fit	8.02	ENST00000375256.5	ZNF367 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 367
chr2_+_10122730 Show fit	7.00	ENST00000304567.10	RRM2 Ensembl NCBI GeneCards UniProt Show fit	ribonucleotide reductase regulatory subunit M2
chr1_-_25906411 Show fit	6.97	ENST00000455785.7	STMN1 Ensembl NCBI GeneCards UniProt Show fit	stathmin 1
chr1_-_25905989 Show fit	6.86	ENST00000399728.5	STMN1 Ensembl NCBI GeneCards UniProt Show fit	stathmin 1
chr6_+_24775413 Show fit	6.70	ENST00000378054.6 ENST00000620958.4 ENST00000476555.5	GMNN Ensembl NCBI GeneCards UniProt Show fit	geminin DNA replication inhibitor
chr8_-_123396412 Show fit	6.56	ENST00000287394.10	ATAD2 Ensembl NCBI GeneCards UniProt Show fit	ATPase family AAA domain containing 2
chr6_+_24774925 Show fit	6.28	ENST00000356509.7 ENST00000230056.8	GMNN Ensembl NCBI GeneCards UniProt Show fit	geminin DNA replication inhibitor
chr3_+_44761765 Show fit	6.14	ENST00000326047.9	KIF15 Ensembl NCBI GeneCards UniProt Show fit	kinesin family member 15
chr15_+_40695423 Show fit	5.98	ENST00000526763.6 ENST00000532743.6	RAD51 Ensembl NCBI GeneCards UniProt Show fit	RAD51 recombinase
chr11_-_19241598 Show fit	5.96	ENST00000532666.1 ENST00000527884.5 ENST00000620009.4	E2F8 Ensembl NCBI GeneCards UniProt Show fit	E2F transcription factor 8
chr7_-_148884266 Show fit	5.91	ENST00000483967.5 ENST00000320356.7	EZH2 Ensembl NCBI GeneCards UniProt Show fit	enhancer of zeste 2 polycomb repressive complex 2 subunit
chr9_-_120877026 Show fit	5.85	ENST00000436309.5	PHF19 Ensembl NCBI GeneCards UniProt Show fit	PHD finger protein 19
chr11_-_19240936 Show fit	5.82	ENST00000250024.9	E2F8 Ensembl NCBI GeneCards UniProt Show fit	E2F transcription factor 8
chr7_-_148884159 Show fit	5.77	ENST00000478654.5 ENST00000460911.5 ENST00000350995.6	EZH2 Ensembl NCBI GeneCards UniProt Show fit	enhancer of zeste 2 polycomb repressive complex 2 subunit
chr7_-_158704740 Show fit	5.66	ENST00000409339.3 ENST00000356309.8 ENST00000409423.5	NCAPG2 Ensembl NCBI GeneCards UniProt Show fit	non-SMC condensin II complex subunit G2
chr7_-_100101915 Show fit	5.62	ENST00000621318.4 ENST00000343023.10	MCM7 Ensembl NCBI GeneCards UniProt Show fit	minichromosome maintenance complex component 7
chr10_+_13161543 Show fit	5.60	ENST00000378714.8 ENST00000479669.5 ENST00000484800.6	MCM10 Ensembl NCBI GeneCards UniProt Show fit	minichromosome maintenance 10 replication initiation factor
chr3_-_48188356 Show fit	5.25	ENST00000351231.7 ENST00000437972.1 ENST00000302506.8	CDC25A Ensembl NCBI GeneCards UniProt Show fit	cell division cycle 25A
chr16_+_88803776 Show fit	5.07	ENST00000301019.9	CDT1 Ensembl NCBI GeneCards UniProt Show fit	chromatin licensing and DNA replication factor 1
chr2_-_234497035 Show fit	5.00	ENST00000390645.2 ENST00000339728.6	ARL4C Ensembl NCBI GeneCards UniProt Show fit	ADP ribosylation factor like GTPase 4C
chr11_-_119095456 Show fit	4.73	ENST00000530167.1	H2AX Ensembl NCBI GeneCards UniProt Show fit	H2A.X variant histone
chr8_-_119855838 Show fit	4.52	ENST00000313655.5	DSCC1 Ensembl NCBI GeneCards UniProt Show fit	DNA replication and sister chromatid cohesion 1
chr15_+_32615501 Show fit	4.49	ENST00000361627.8 ENST00000567348.5 ENST00000563864.5 ENST00000543522.5	ARHGAP11A Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 11A
chr15_+_40695129 Show fit	4.47	ENST00000423169.6 ENST00000557850.5 ENST00000382643.7 ENST00000267868.8 ENST00000645673.2	RAD51 Ensembl NCBI GeneCards UniProt Show fit	RAD51 recombinase
chr10_+_94545777 Show fit	4.44	ENST00000348459.10 ENST00000419900.5 ENST00000630929.2	HELLS Ensembl NCBI GeneCards UniProt Show fit	helicase, lymphoid specific
chr15_-_66356672 Show fit	4.42	ENST00000261881.9	TIPIN Ensembl NCBI GeneCards UniProt Show fit	TIMELESS interacting protein
chr10_+_94545852 Show fit	4.41	ENST00000394036.5 ENST00000394045.5	HELLS Ensembl NCBI GeneCards UniProt Show fit	helicase, lymphoid specific
chr9_-_35079923 Show fit	4.36	ENST00000378643.8 ENST00000448890.1	FANCG Ensembl NCBI GeneCards UniProt Show fit	FA complementation group G
chr9_-_120877167 Show fit	4.22	ENST00000373896.8 ENST00000312189.10	PHF19 Ensembl NCBI GeneCards UniProt Show fit	PHD finger protein 19
chr1_-_25906931 Show fit	3.84	ENST00000357865.6	STMN1 Ensembl NCBI GeneCards UniProt Show fit	stathmin 1
chr6_-_35688907 Show fit	3.65	ENST00000539068.5 ENST00000357266.9	FKBP5 Ensembl NCBI GeneCards UniProt Show fit	FKBP prolyl isomerase 5
chrX_+_48696719 Show fit	3.50	ENST00000376687.4	SUV39H1 Ensembl NCBI GeneCards UniProt Show fit	suppressor of variegation 3-9 homolog 1
chr11_+_62856149 Show fit	3.49	ENST00000535296.5	SLC3A2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 3 member 2
chr16_-_2980406 Show fit	3.36	ENST00000431515.6 ENST00000574385.5 ENST00000576268.1 ENST00000574730.5 ENST00000262300.13 ENST00000575632.5 ENST00000573944.5	PKMYT1 Ensembl NCBI GeneCards UniProt Show fit	protein kinase, membrane associated tyrosine/threonine 1
chr11_+_62856004 Show fit	3.32	ENST00000680729.1	SLC3A2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 3 member 2
chr11_+_62856072 Show fit	3.31	ENST00000377890.6 ENST00000681467.1 ENST00000538084.2 ENST00000681569.1 ENST00000377891.6 ENST00000680725.1 ENST00000377889.6	SLC3A2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 3 member 2
chr6_+_37170133 Show fit	3.30	ENST00000373509.6	PIM1 Ensembl NCBI GeneCards UniProt Show fit	Pim-1 proto-oncogene, serine/threonine kinase
chr1_-_23531206 Show fit	3.27	ENST00000361729.3	E2F2 Ensembl NCBI GeneCards UniProt Show fit	E2F transcription factor 2
chr1_-_148679734 Show fit	3.24	ENST00000606877.2 ENST00000593495.3	NBPF14 Ensembl NCBI GeneCards UniProt Show fit NOTCH2NLB Ensembl NCBI GeneCards UniProt Show fit	NBPF member 14 notch 2 N-terminal like B
chr5_+_36151989 Show fit	3.23	ENST00000274254.9	SKP2 Ensembl NCBI GeneCards UniProt Show fit	S-phase kinase associated protein 2
chr1_+_120723939 Show fit	3.17	ENST00000624419.2 ENST00000652763.1 ENST00000620612.5	NOTCH2NLR Ensembl NCBI GeneCards UniProt Show fit NBPF26 Ensembl NCBI GeneCards UniProt Show fit	notch 2 N-terminal like R (pseudogene) NBPF member 26
chr7_-_94656197 Show fit	3.15	ENST00000643903.1 ENST00000644122.1 ENST00000447873.6 ENST00000644816.1 ENST00000644375.1	SGCE Ensembl NCBI GeneCards UniProt Show fit	sarcoglycan epsilon
chr16_-_85688912 Show fit	3.10	ENST00000253462.8	GINS2 Ensembl NCBI GeneCards UniProt Show fit	GINS complex subunit 2
chr8_+_26577843 Show fit	3.04	ENST00000311151.9	DPYSL2 Ensembl NCBI GeneCards UniProt Show fit	dihydropyrimidinase like 2
chr17_+_40287861 Show fit	2.98	ENST00000209728.9 ENST00000580824.5 ENST00000577249.1 ENST00000649662.1	CDC6 Ensembl NCBI GeneCards UniProt Show fit	cell division cycle 6
chr10_-_73874461 Show fit	2.98	ENST00000305762.11	CAMK2G Ensembl NCBI GeneCards UniProt Show fit	calcium/calmodulin dependent protein kinase II gamma
chr5_-_80654552 Show fit	2.96	ENST00000511032.5 ENST00000504396.1 ENST00000505337.5	DHFR Ensembl NCBI GeneCards UniProt Show fit	dihydrofolate reductase
chr18_+_36297661 Show fit	2.95	ENST00000257209.8 ENST00000590592.5 ENST00000359247.8	FHOD3 Ensembl NCBI GeneCards UniProt Show fit	formin homology 2 domain containing 3
chr2_-_17753792 Show fit	2.88	ENST00000448223.7 ENST00000621152.4 ENST00000351948.8	SMC6 Ensembl NCBI GeneCards UniProt Show fit	structural maintenance of chromosomes 6
chr8_+_47961028 Show fit	2.88	ENST00000650216.1	MCM4 Ensembl NCBI GeneCards UniProt Show fit	minichromosome maintenance complex component 4
chr5_+_36152077 Show fit	2.86	ENST00000546211.6 ENST00000620197.5 ENST00000678270.1 ENST00000679015.1 ENST00000678580.1 ENST00000274255.11 ENST00000508514.5	SKP2 Ensembl NCBI GeneCards UniProt Show fit	S-phase kinase associated protein 2
chr7_+_94656325 Show fit	2.86	ENST00000482108.1 ENST00000488574.5 ENST00000612748.1 ENST00000613043.1	PEG10 Ensembl NCBI GeneCards UniProt Show fit	paternally expressed 10
chr7_-_94655993 Show fit	2.82	ENST00000647110.1 ENST00000647048.1 ENST00000643020.1 ENST00000644682.1 ENST00000646119.1 ENST00000646265.1 ENST00000645445.1 ENST00000647334.1 ENST00000645262.1 ENST00000428696.7 ENST00000647096.1 ENST00000642394.1 ENST00000645725.1 ENST00000647351.1 ENST00000646943.1 ENST00000648936.2 ENST00000642707.1 ENST00000645109.1 ENST00000646489.1 ENST00000642933.1 ENST00000643128.1 ENST00000445866.7 ENST00000645101.1 ENST00000644116.1 ENST00000642441.1 ENST00000646879.1 ENST00000647018.1	SGCE Ensembl NCBI GeneCards UniProt Show fit	sarcoglycan epsilon
chr22_+_41998780 Show fit	2.82	ENST00000328823.13	WBP2NL Ensembl NCBI GeneCards UniProt Show fit	WBP2 N-terminal like
chr7_-_94656160 Show fit	2.79	ENST00000644609.1 ENST00000643272.1 ENST00000646137.1 ENST00000646098.1 ENST00000643193.1 ENST00000437425.7 ENST00000644551.1 ENST00000415788.3	SGCE Ensembl NCBI GeneCards UniProt Show fit	sarcoglycan epsilon
chrX_-_132489842 Show fit	2.79	ENST00000436215.5	MBNL3 Ensembl NCBI GeneCards UniProt Show fit	muscleblind like splicing regulator 3
chr9_-_111038061 Show fit	2.76	ENST00000358883.8	LPAR1 Ensembl NCBI GeneCards UniProt Show fit	lysophosphatidic acid receptor 1
chr11_+_47215032 Show fit	2.74	ENST00000622090.4 ENST00000378600.7 ENST00000378603.7	DDB2 Ensembl NCBI GeneCards UniProt Show fit	damage specific DNA binding protein 2
chr11_+_65040895 Show fit	2.57	ENST00000531072.1 ENST00000398846.6	SAC3D1 Ensembl NCBI GeneCards UniProt Show fit	SAC3 domain containing 1
chr16_-_2980282 Show fit	2.57	ENST00000572619.1 ENST00000574415.5 ENST00000440027.6 ENST00000572059.1	PKMYT1 Ensembl NCBI GeneCards UniProt Show fit	protein kinase, membrane associated tyrosine/threonine 1
chr9_-_111038037 Show fit	2.56	ENST00000374431.7	LPAR1 Ensembl NCBI GeneCards UniProt Show fit	lysophosphatidic acid receptor 1
chr22_-_37519349 Show fit	2.47	ENST00000251973.10	CARD10 Ensembl NCBI GeneCards UniProt Show fit	caspase recruitment domain family member 10
chr11_+_65041203 Show fit	2.46	ENST00000652489.1 ENST00000674184.1	SAC3D1 Ensembl NCBI GeneCards UniProt Show fit	SAC3 domain containing 1
chr22_-_37519528 Show fit	2.44	ENST00000403299.5	CARD10 Ensembl NCBI GeneCards UniProt Show fit	caspase recruitment domain family member 10
chr19_-_10194898 Show fit	2.43	ENST00000359526.9 ENST00000679103.1 ENST00000676610.1 ENST00000678804.1 ENST00000679313.1 ENST00000677946.1	DNMT1 Ensembl NCBI GeneCards UniProt Show fit	DNA methyltransferase 1
chr12_-_121800558 Show fit	2.42	ENST00000546227.5	RHOF Ensembl NCBI GeneCards UniProt Show fit	ras homolog family member F, filopodia associated
chr9_-_111038425 Show fit	2.38	ENST00000441240.1 ENST00000683809.1	LPAR1 Ensembl NCBI GeneCards UniProt Show fit	lysophosphatidic acid receptor 1
chr8_+_47960883 Show fit	2.32	ENST00000648407.1 ENST00000649838.1 ENST00000649919.1 ENST00000262105.6 ENST00000649973.1	MCM4 Ensembl NCBI GeneCards UniProt Show fit	minichromosome maintenance complex component 4
chr10_-_56361235 Show fit	2.31	ENST00000373944.8 ENST00000361148.6 ENST00000395405.5	ZWINT Ensembl NCBI GeneCards UniProt Show fit	ZW10 interacting kinetochore protein
chr13_+_32315071 Show fit	2.27	ENST00000544455.6	BRCA2 Ensembl NCBI GeneCards UniProt Show fit	BRCA2 DNA repair associated
chr1_-_100132892 Show fit	2.21	ENST00000287482.6	SASS6 Ensembl NCBI GeneCards UniProt Show fit	SAS-6 centriolar assembly protein
chr1_-_47314089 Show fit	2.15	ENST00000360380.7 ENST00000371877.8 ENST00000447475.7	STIL Ensembl NCBI GeneCards UniProt Show fit	STIL centriolar assembly protein
chr15_-_70096604 Show fit	2.14	ENST00000559048.5 ENST00000560939.5 ENST00000440567.7 ENST00000557907.5 ENST00000558379.5 ENST00000559929.5	TLE3 Ensembl NCBI GeneCards UniProt Show fit	TLE family member 3, transcriptional corepressor
chr10_-_73247241 Show fit	2.14	ENST00000372950.6	DNAJC9 Ensembl NCBI GeneCards UniProt Show fit	DnaJ heat shock protein family (Hsp40) member C9
chr10_-_73874568 Show fit	2.03	ENST00000322635.7 ENST00000322680.7 ENST00000394762.7 ENST00000680035.1	CAMK2G Ensembl NCBI GeneCards UniProt Show fit	calcium/calmodulin dependent protein kinase II gamma
chr14_+_32934383 Show fit	2.01	ENST00000551634.6	NPAS3 Ensembl NCBI GeneCards UniProt Show fit	neuronal PAS domain protein 3
chr9_+_104094557 Show fit	2.00	ENST00000374787.7	SMC2 Ensembl NCBI GeneCards UniProt Show fit	structural maintenance of chromosomes 2
chrX_+_24693879 Show fit	1.96	ENST00000379068.8 ENST00000677890.1 ENST00000379059.7	POLA1 Ensembl NCBI GeneCards UniProt Show fit	DNA polymerase alpha 1, catalytic subunit
chr13_+_32315468 Show fit	1.95	ENST00000530893.6 ENST00000380152.8	BRCA2 Ensembl NCBI GeneCards UniProt Show fit	BRCA2 DNA repair associated
chr11_+_47214937 Show fit	1.93	ENST00000256996.9	DDB2 Ensembl NCBI GeneCards UniProt Show fit	damage specific DNA binding protein 2
chr20_-_37095985 Show fit	1.92	ENST00000344359.7 ENST00000373664.8	RBL1 Ensembl NCBI GeneCards UniProt Show fit	RB transcriptional corepressor like 1
chr5_-_177311882 Show fit	1.92	ENST00000513169.1 ENST00000423571.6 ENST00000502529.1 ENST00000427908.6	MXD3 Ensembl NCBI GeneCards UniProt Show fit	MAX dimerization protein 3
chr11_-_74731385 Show fit	1.84	ENST00000622063.4 ENST00000376332.8	CHRDL2 Ensembl NCBI GeneCards UniProt Show fit	chordin like 2
chr2_+_17753852 Show fit	1.83	ENST00000317402.11	GEN1 Ensembl NCBI GeneCards UniProt Show fit	GEN1 Holliday junction 5' flap endonuclease
chr20_-_33686371 Show fit	1.75	ENST00000343380.6	E2F1 Ensembl NCBI GeneCards UniProt Show fit	E2F transcription factor 1
chr3_+_10026409 Show fit	1.73	ENST00000287647.7 ENST00000676013.1 ENST00000675286.1 ENST00000419585.5	FANCD2 Ensembl NCBI GeneCards UniProt Show fit	FA complementation group D2
chr8_-_124728273 Show fit	1.71	ENST00000325064.9 ENST00000518547.6	MTSS1 Ensembl NCBI GeneCards UniProt Show fit	MTSS I-BAR domain containing 1
chr2_+_27275429 Show fit	1.69	ENST00000420191.5 ENST00000296097.8	DNAJC5G Ensembl NCBI GeneCards UniProt Show fit	DnaJ heat shock protein family (Hsp40) member C5 gamma
chr12_+_93572664 Show fit	1.69	ENST00000551556.2	SOCS2 Ensembl NCBI GeneCards UniProt Show fit	suppressor of cytokine signaling 2
chr10_-_24952573 Show fit	1.67	ENST00000376378.5 ENST00000376376.3 ENST00000320152.11	PRTFDC1 Ensembl NCBI GeneCards UniProt Show fit	phosphoribosyl transferase domain containing 1
chr17_-_43545707 Show fit	1.63	ENST00000545089.5	ETV4 Ensembl NCBI GeneCards UniProt Show fit	ETS variant transcription factor 4
chr2_+_17754116 Show fit	1.63	ENST00000381254.7 ENST00000524465.5 ENST00000532257.1	GEN1 Ensembl NCBI GeneCards UniProt Show fit	GEN1 Holliday junction 5' flap endonuclease
chr6_-_52284677 Show fit	1.54	ENST00000596288.7 ENST00000616552.4 ENST00000229854.12 ENST00000419835.8	MCM3 Ensembl NCBI GeneCards UniProt Show fit	minichromosome maintenance complex component 3
chr2_+_48314637 Show fit	1.54	ENST00000413569.5 ENST00000340553.8	FOXN2 Ensembl NCBI GeneCards UniProt Show fit	forkhead box N2
chr5_-_80654956 Show fit	1.52	ENST00000439211.7	DHFR Ensembl NCBI GeneCards UniProt Show fit	dihydrofolate reductase
chr13_+_113584683 Show fit	1.50	ENST00000375370.10	TFDP1 Ensembl NCBI GeneCards UniProt Show fit	transcription factor Dp-1
chr11_-_74731148 Show fit	1.49	ENST00000263671.9 ENST00000528789.1	CHRDL2 Ensembl NCBI GeneCards UniProt Show fit	chordin like 2
chr12_+_57229694 Show fit	1.49	ENST00000557487.5 ENST00000328923.8 ENST00000555634.5 ENST00000556689.5	SHMT2 Ensembl NCBI GeneCards UniProt Show fit	serine hydroxymethyltransferase 2
chr16_+_58392391 Show fit	1.46	ENST00000426538.6 ENST00000328514.11	GINS3 Ensembl NCBI GeneCards UniProt Show fit	GINS complex subunit 3
chr16_+_58392462 Show fit	1.42	ENST00000318129.6	GINS3 Ensembl NCBI GeneCards UniProt Show fit	GINS complex subunit 3
chr10_-_73874502 Show fit	1.42	ENST00000372765.5 ENST00000351293.7 ENST00000441192.2 ENST00000423381.6	CAMK2G Ensembl NCBI GeneCards UniProt Show fit	calcium/calmodulin dependent protein kinase II gamma
chr12_-_132687307 Show fit	1.42	ENST00000535270.5 ENST00000320574.10	POLE Ensembl NCBI GeneCards UniProt Show fit	DNA polymerase epsilon, catalytic subunit
chr2_+_27275466 Show fit	1.40	ENST00000404433.5 ENST00000406962.1	DNAJC5G Ensembl NCBI GeneCards UniProt Show fit	DnaJ heat shock protein family (Hsp40) member C5 gamma
chr3_-_133661896 Show fit	1.37	ENST00000260810.10	TOPBP1 Ensembl NCBI GeneCards UniProt Show fit	DNA topoisomerase II binding protein 1
chr9_+_104094260 Show fit	1.35	ENST00000286398.11 ENST00000440179.5 ENST00000374793.8	SMC2 Ensembl NCBI GeneCards UniProt Show fit	structural maintenance of chromosomes 2
chr4_+_177309866 Show fit	1.34	ENST00000264596.4	NEIL3 Ensembl NCBI GeneCards UniProt Show fit	nei like DNA glycosylase 3
chr2_+_27275461 Show fit	1.31	ENST00000402462.5	DNAJC5G Ensembl NCBI GeneCards UniProt Show fit	DnaJ heat shock protein family (Hsp40) member C5 gamma
chr22_-_28741783 Show fit	1.29	ENST00000439200.5 ENST00000405598.5 ENST00000398017.3 ENST00000649563.1 ENST00000650281.1 ENST00000425190.7 ENST00000404276.6 ENST00000650233.1 ENST00000348295.7 ENST00000382580.6	CHEK2 Ensembl NCBI GeneCards UniProt Show fit	checkpoint kinase 2
chrX_+_101098165 Show fit	1.28	ENST00000684367.1 ENST00000423383.3 ENST00000682304.1 ENST00000682095.1 ENST00000403304.6 ENST00000435570.1	CENPI Ensembl NCBI GeneCards UniProt Show fit	centromere protein I
chr17_-_43545891 Show fit	1.26	ENST00000591713.5 ENST00000538265.5	ETV4 Ensembl NCBI GeneCards UniProt Show fit	ETS variant transcription factor 4
chr19_-_45406327 Show fit	1.24	ENST00000593226.5 ENST00000418234.6	PPP1R13L Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1 regulatory subunit 13 like
chr6_+_20401864 Show fit	1.24	ENST00000346618.8 ENST00000613242.4	E2F3 Ensembl NCBI GeneCards UniProt Show fit	E2F transcription factor 3
chr19_-_10569022 Show fit	1.21	ENST00000335766.2	CDKN2D Ensembl NCBI GeneCards UniProt Show fit	cyclin dependent kinase inhibitor 2D
chr22_+_20117497 Show fit	1.21	ENST00000331821.7 ENST00000411892.5	RANBP1 Ensembl NCBI GeneCards UniProt Show fit	RAN binding protein 1
chr19_-_10568968 Show fit	1.20	ENST00000393599.3	CDKN2D Ensembl NCBI GeneCards UniProt Show fit	cyclin dependent kinase inhibitor 2D
chrX_+_46837034 Show fit	1.19	ENST00000218340.4	RP2 Ensembl NCBI GeneCards UniProt Show fit	RP2 activator of ARL3 GTPase
chr9_-_95317671 Show fit	1.17	ENST00000490972.7 ENST00000647778.1 ENST00000649611.1 ENST00000289081.8	FANCC Ensembl NCBI GeneCards UniProt Show fit	FA complementation group C
chr17_-_43545636 Show fit	1.16	ENST00000393664.6	ETV4 Ensembl NCBI GeneCards UniProt Show fit	ETS variant transcription factor 4
chr12_+_57230086 Show fit	1.15	ENST00000414700.7 ENST00000557703.5	SHMT2 Ensembl NCBI GeneCards UniProt Show fit	serine hydroxymethyltransferase 2
chr14_+_74881887 Show fit	1.14	ENST00000334220.9 ENST00000626051.1 ENST00000554806.5	DLST Ensembl NCBI GeneCards UniProt Show fit	dihydrolipoamide S-succinyltransferase
chr17_-_43546323 Show fit	1.12	ENST00000545954.5 ENST00000319349.10	ETV4 Ensembl NCBI GeneCards UniProt Show fit	ETS variant transcription factor 4
chr6_+_31739948 Show fit	1.12	ENST00000375755.8 ENST00000425703.5 ENST00000375750.9 ENST00000375703.7 ENST00000375740.7	MSH5 Ensembl NCBI GeneCards UniProt Show fit	mutS homolog 5
chr22_+_20117734 Show fit	1.12	ENST00000416427.5 ENST00000421656.5 ENST00000423859.5 ENST00000418705.2	RANBP1 Ensembl NCBI GeneCards UniProt Show fit	RAN binding protein 1
chr2_+_152718604 Show fit	1.09	ENST00000326446.10	ARL6IP6 Ensembl NCBI GeneCards UniProt Show fit	ADP ribosylation factor like GTPase 6 interacting protein 6
chr6_-_18264475 Show fit	1.06	ENST00000515742.2 ENST00000651624.1 ENST00000507591.2 ENST00000652689.1 ENST00000244776.11 ENST00000503715.5	DEK Ensembl NCBI GeneCards UniProt Show fit	DEK proto-oncogene
chr19_+_50384323 Show fit	1.05	ENST00000599857.7 ENST00000613923.6 ENST00000601098.6 ENST00000440232.7 ENST00000595904.6 ENST00000593887.1	POLD1 Ensembl NCBI GeneCards UniProt Show fit	DNA polymerase delta 1, catalytic subunit
chr12_+_56128217 Show fit	1.05	ENST00000267113.4 ENST00000394048.10	ESYT1 Ensembl NCBI GeneCards UniProt Show fit	extended synaptotagmin 1
chr2_-_46941710 Show fit	1.04	ENST00000409207.5	MCFD2 Ensembl NCBI GeneCards UniProt Show fit	multiple coagulation factor deficiency 2, ER cargo receptor complex subunit
chrX_+_21940693 Show fit	1.03	ENST00000404933.7 ENST00000379404.5	SMS Ensembl NCBI GeneCards UniProt Show fit	spermine synthase
chr2_+_218568865 Show fit	1.03	ENST00000295701.9	CNOT9 Ensembl NCBI GeneCards UniProt Show fit	CCR4-NOT transcription complex subunit 9
chr1_-_180502536 Show fit	1.02	ENST00000367595.4	ACBD6 Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA binding domain containing 6
chr10_+_71964373 Show fit	0.98	ENST00000373115.5	CHST3 Ensembl NCBI GeneCards UniProt Show fit	carbohydrate sulfotransferase 3
chrX_-_107000185 Show fit	0.98	ENST00000355610.9	MORC4 Ensembl NCBI GeneCards UniProt Show fit	MORC family CW-type zinc finger 4
chr15_-_70892412 Show fit	0.96	ENST00000249861.9	THAP10 Ensembl NCBI GeneCards UniProt Show fit	THAP domain containing 10
chr1_-_243255170 Show fit	0.94	ENST00000366542.6	CEP170 Ensembl NCBI GeneCards UniProt Show fit	centrosomal protein 170
chr4_+_70993542 Show fit	0.93	ENST00000504730.5 ENST00000504952.1 ENST00000286648.10	DCK Ensembl NCBI GeneCards UniProt Show fit	deoxycytidine kinase
chr1_+_25272492 Show fit	0.92	ENST00000454452.6	RHD Ensembl NCBI GeneCards UniProt Show fit	Rh blood group D antigen
chr1_-_243255320 Show fit	0.91	ENST00000366544.5 ENST00000366543.5	CEP170 Ensembl NCBI GeneCards UniProt Show fit	centrosomal protein 170
chr9_+_504675 Show fit	0.89	ENST00000382297.7 ENST00000674102.1 ENST00000619269.4	KANK1 Ensembl NCBI GeneCards UniProt Show fit	KN motif and ankyrin repeat domains 1
chr17_-_58007217 Show fit	0.87	ENST00000258962.5 ENST00000582730.6 ENST00000584773.5 ENST00000585096.1	SRSF1 Ensembl NCBI GeneCards UniProt Show fit	serine and arginine rich splicing factor 1
chr18_+_21612274 Show fit	0.87	ENST00000579618.1 ENST00000300413.10 ENST00000582475.1	SNRPD1 Ensembl NCBI GeneCards UniProt Show fit	small nuclear ribonucleoprotein D1 polypeptide
chr6_+_36027773 Show fit	0.86	ENST00000468133.5	MAPK14 Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase 14
chr10_-_75401746 Show fit	0.85	ENST00000372524.5	ZNF503 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 503
chr12_+_4809176 Show fit	0.84	ENST00000280684.3	KCNA6 Ensembl NCBI GeneCards UniProt Show fit	potassium voltage-gated channel subfamily A member 6
chr20_-_5119945 Show fit	0.84	ENST00000379143.10	PCNA Ensembl NCBI GeneCards UniProt Show fit	proliferating cell nuclear antigen
chr20_+_5950630 Show fit	0.83	ENST00000378883.5 ENST00000378896.7 ENST00000378886.6 ENST00000610722.4	MCM8 Ensembl NCBI GeneCards UniProt Show fit	minichromosome maintenance 8 homologous recombination repair factor
chr20_-_62407274 Show fit	0.82	ENST00000279101.9	CABLES2 Ensembl NCBI GeneCards UniProt Show fit	Cdk5 and Abl enzyme substrate 2
chrX_+_123961696 Show fit	0.81	ENST00000371145.8 ENST00000371157.7 ENST00000371144.7	STAG2 Ensembl NCBI GeneCards UniProt Show fit	stromal antigen 2
chr4_-_129093454 Show fit	0.79	ENST00000281142.10 ENST00000511426.5	SCLT1 Ensembl NCBI GeneCards UniProt Show fit	sodium channel and clathrin linker 1
chr1_+_109910892 Show fit	0.78	ENST00000369802.7 ENST00000420111.6	CSF1 Ensembl NCBI GeneCards UniProt Show fit	colony stimulating factor 1
chr8_+_93916882 Show fit	0.77	ENST00000297598.5 ENST00000520728.5 ENST00000518107.5 ENST00000396200.3	PDP1 Ensembl NCBI GeneCards UniProt Show fit	pyruvate dehyrogenase phosphatase catalytic subunit 1
chr1_+_35573308 Show fit	0.75	ENST00000373235.4	TFAP2E Ensembl NCBI GeneCards UniProt Show fit	transcription factor AP-2 epsilon
chr1_+_149390612 Show fit	0.75	ENST00000650865.1 ENST00000652191.1 ENST00000621744.4	NOTCH2NLC Ensembl NCBI GeneCards UniProt Show fit ENSG00000286185.1 Ensembl NCBI GeneCards UniProt Show fit	notch 2 N-terminal like C novel protein, identical to neuroblastoma breakpoint family, member 19 NBPF19
chr1_+_109910986 Show fit	0.74	ENST00000369801.1	CSF1 Ensembl NCBI GeneCards UniProt Show fit	colony stimulating factor 1
chr19_+_2236816 Show fit	0.71	ENST00000221494.10	SF3A2 Ensembl NCBI GeneCards UniProt Show fit	splicing factor 3a subunit 2
chr14_+_21070273 Show fit	0.71	ENST00000555038.5 ENST00000298694.9	ARHGEF40 Ensembl NCBI GeneCards UniProt Show fit	Rho guanine nucleotide exchange factor 40
chr5_-_141619049 Show fit	0.70	ENST00000647433.1 ENST00000253811.10 ENST00000389057.9 ENST00000398557.8	DIAPH1 Ensembl NCBI GeneCards UniProt Show fit	diaphanous related formin 1
chr5_-_141618957 Show fit	0.70	ENST00000389054.8	DIAPH1 Ensembl NCBI GeneCards UniProt Show fit	diaphanous related formin 1
chr1_+_25272527 Show fit	0.70	ENST00000342055.9 ENST00000357542.8 ENST00000417538.6 ENST00000423810.6 ENST00000568195.5	RHD Ensembl NCBI GeneCards UniProt Show fit	Rh blood group D antigen
chr6_+_27808163 Show fit	0.69	ENST00000358739.4	H2AC13 Ensembl NCBI GeneCards UniProt Show fit	H2A clustered histone 13
chr1_-_222712428 Show fit	0.67	ENST00000355727.3 ENST00000340020.11	AIDA Ensembl NCBI GeneCards UniProt Show fit	axin interactor, dorsalization associated
chr4_-_129093548 Show fit	0.67	ENST00000503401.1	SCLT1 Ensembl NCBI GeneCards UniProt Show fit	sodium channel and clathrin linker 1
chr1_-_150010675 Show fit	0.66	ENST00000417191.2 ENST00000581312.6	OTUD7B Ensembl NCBI GeneCards UniProt Show fit	OTU deubiquitinase 7B
chr6_+_36027796 Show fit	0.66	ENST00000229794.9	MAPK14 Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase 14
chr15_+_41559189 Show fit	0.62	ENST00000263798.8	TYRO3 Ensembl NCBI GeneCards UniProt Show fit	TYRO3 protein tyrosine kinase
chr19_-_49361475 Show fit	0.62	ENST00000598810.5	TEAD2 Ensembl NCBI GeneCards UniProt Show fit	TEA domain transcription factor 2
chr8_+_127736220 Show fit	0.60	ENST00000524013.2 ENST00000621592.8	MYC Ensembl NCBI GeneCards UniProt Show fit	MYC proto-oncogene, bHLH transcription factor
chrX_+_132023294 Show fit	0.59	ENST00000481105.5 ENST00000354719.10 ENST00000394334.7 ENST00000394335.6	STK26 Ensembl NCBI GeneCards UniProt Show fit	serine/threonine kinase 26
chr2_-_27409523 Show fit	0.59	ENST00000344034.5	PPM1G Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase, Mg2+/Mn2+ dependent 1G
chr9_-_128128102 Show fit	0.59	ENST00000617202.4	PTGES2 Ensembl NCBI GeneCards UniProt Show fit	prostaglandin E synthase 2
chr3_-_119677346 Show fit	0.58	ENST00000484810.5 ENST00000497116.1 ENST00000261070.7	COX17 Ensembl NCBI GeneCards UniProt Show fit	cytochrome c oxidase copper chaperone COX17
chr6_+_36027677 Show fit	0.56	ENST00000622903.4 ENST00000229795.7	MAPK14 Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase 14
chr3_+_14947568 Show fit	0.55	ENST00000413118.5 ENST00000425241.5	NR2C2 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 2 group C member 2
chr12_-_12696171 Show fit	0.55	ENST00000651487.1 ENST00000332427.6 ENST00000540796.5	GPR19 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 19
chrX_-_11665908 Show fit	0.55	ENST00000337414.9	ARHGAP6 Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 6
chr12_+_121888751 Show fit	0.55	ENST00000261817.6 ENST00000538613.5 ENST00000542602.1 ENST00000541212.6	PSMD9 Ensembl NCBI GeneCards UniProt Show fit	proteasome 26S subunit, non-ATPase 9
chr1_-_146229000 Show fit	0.55	ENST00000612520.2 ENST00000579793.6 ENST00000362074.7	NBPF10 Ensembl NCBI GeneCards UniProt Show fit NOTCH2NLA Ensembl NCBI GeneCards UniProt Show fit	NBPF member 10 notch 2 N-terminal like A
chr17_-_17281232 Show fit	0.54	ENST00000417352.5 ENST00000268717.10	COPS3 Ensembl NCBI GeneCards UniProt Show fit	COP9 signalosome subunit 3
chr7_+_26201705 Show fit	0.54	ENST00000396386.7 ENST00000456948.5 ENST00000409747.5	CBX3 Ensembl NCBI GeneCards UniProt Show fit	chromobox 3
chr8_+_127736046 Show fit	0.54	ENST00000641036.1 ENST00000377970.6	MYC Ensembl NCBI GeneCards UniProt Show fit	MYC proto-oncogene, bHLH transcription factor
chr6_-_27814757 Show fit	0.54	ENST00000333151.5	H2AC14 Ensembl NCBI GeneCards UniProt Show fit	H2A clustered histone 14
chr5_+_76083398 Show fit	0.53	ENST00000322285.7	SV2C Ensembl NCBI GeneCards UniProt Show fit	synaptic vesicle glycoprotein 2C
chr3_-_14178569 Show fit	0.52	ENST00000285021.12	XPC Ensembl NCBI GeneCards UniProt Show fit	XPC complex subunit, DNA damage recognition and repair factor
chr3_+_14947680 Show fit	0.51	ENST00000435454.5 ENST00000323373.10	NR2C2 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 2 group C member 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.9	11.8	GO:0032877	positive regulation of DNA endoreduplication(GO:0032877)
3.9	11.7	GO:1904772	hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
3.8	49.4	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
3.6	18.0	GO:0071163	DNA replication preinitiation complex assembly(GO:0071163)
3.0	32.6	GO:0010216	maintenance of DNA methylation(GO:0010216)
2.5	19.7	GO:0090166	regulation of Schwann cell differentiation(GO:0014038) Golgi disassembly(GO:0090166)
2.4	28.2	GO:0070494	regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
1.7	10.1	GO:0060356	leucine import(GO:0060356)
1.5	7.7	GO:1904566	response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
1.5	4.5	GO:0046452	dihydrofolate metabolic process(GO:0046452)
1.4	4.2	GO:1990426	homologous recombination-dependent replication fork processing(GO:1990426)
1.3	15.6	GO:1902969	mitotic DNA replication(GO:1902969)
1.3	5.0	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
1.2	3.5	GO:0071140	resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
1.1	4.2	GO:0006272	leading strand elongation(GO:0006272)
1.0	6.1	GO:0071460	cellular response to cell-matrix adhesion(GO:0071460)
0.9	9.3	GO:0061087	positive regulation of histone H3-K27 methylation(GO:0061087)
0.9	25.8	GO:0009263	deoxyribonucleotide biosynthetic process(GO:0009263)
0.9	4.5	GO:0034421	post-translational protein acetylation(GO:0034421)
0.7	3.0	GO:1904116	response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.7	4.4	GO:0048478	replication fork protection(GO:0048478)
0.7	2.6	GO:0019264	glycine biosynthetic process from serine(GO:0019264)
0.6	6.6	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.6	5.7	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.6	2.8	GO:0007343	egg activation(GO:0007343)
0.6	3.4	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.6	1.7	GO:1901069	guanosine-containing compound catabolic process(GO:1901069)
0.5	23.9	GO:0006270	DNA replication initiation(GO:0006270)
0.5	1.9	GO:0060611	positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.4	2.7	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
0.4	3.5	GO:0036123	histone H3-K9 dimethylation(GO:0036123)
0.4	2.9	GO:0000722	telomere maintenance via recombination(GO:0000722)
0.4	19.9	GO:0035825	reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.4	1.1	GO:0006287	base-excision repair, gap-filling(GO:0006287)
0.3	2.1	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) positive regulation of interleukin-12 secretion(GO:2001184)
0.3	1.7	GO:0030035	microspike assembly(GO:0030035)
0.3	4.7	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.3	1.1	GO:0090095	regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.3	0.3	GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.3	3.3	GO:0070561	vitamin D receptor signaling pathway(GO:0070561)
0.3	2.2	GO:0033504	floor plate development(GO:0033504)
0.3	6.3	GO:1901897	regulation of relaxation of cardiac muscle(GO:1901897)
0.3	2.3	GO:0046604	positive regulation of mitotic centrosome separation(GO:0046604)
0.2	15.8	GO:0019985	translesion synthesis(GO:0019985)
0.2	1.1	GO:0033512	L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.2	0.9	GO:2000393	negative regulation of lamellipodium morphogenesis(GO:2000393)
0.2	2.4	GO:0048102	autophagic cell death(GO:0048102)
0.2	2.9	GO:0006271	DNA strand elongation involved in DNA replication(GO:0006271)
0.2	4.9	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.2	7.4	GO:0036297	interstrand cross-link repair(GO:0036297)
0.2	0.5	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.2	1.4	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.2	0.8	GO:2000327	regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.1	0.6	GO:1904732	regulation of electron carrier activity(GO:1904732)
0.1	5.2	GO:1902751	positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.1	1.2	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.1	1.0	GO:0008215	spermine metabolic process(GO:0008215)
0.1	1.9	GO:0035372	protein localization to microtubule(GO:0035372)
0.1	2.9	GO:0051639	actin filament network formation(GO:0051639)
0.1	0.2	GO:0019230	proprioception(GO:0019230)
0.1	0.7	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1	0.9	GO:0009157	deoxyribonucleoside monophosphate biosynthetic process(GO:0009157)
0.1	0.3	GO:0060266	negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1	0.9	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.1	0.4	GO:0006617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.1	0.3	GO:0097476	spinal cord motor neuron migration(GO:0097476)
0.1	1.5	GO:2001032	regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.1	1.8	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.1	1.0	GO:0006301	postreplication repair(GO:0006301)
0.1	0.9	GO:0070315	G1 to G0 transition involved in cell differentiation(GO:0070315)
0.1	2.7	GO:0015695	organic cation transport(GO:0015695)
0.1	3.0	GO:0032456	endocytic recycling(GO:0032456)
0.1	0.9	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.1	0.8	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.1	1.2	GO:0003215	cardiac right ventricle morphogenesis(GO:0003215)
0.1	6.1	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1	0.8	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.1	2.1	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.1	GO:0034970	histone H3-R2 methylation(GO:0034970)
0.0	0.5	GO:0031573	intra-S DNA damage checkpoint(GO:0031573)
0.0	2.1	GO:0006284	base-excision repair(GO:0006284)
0.0	0.2	GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) AMP biosynthetic process(GO:0006167) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0	5.6	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.0	0.6	GO:0048368	lateral mesoderm development(GO:0048368)
0.0	0.5	GO:0000338	protein deneddylation(GO:0000338)
0.0	0.1	GO:0021722	superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.0	0.3	GO:0014043	negative regulation of neuron maturation(GO:0014043)
0.0	1.4	GO:0007099	centriole replication(GO:0007099)
0.0	0.2	GO:0070836	caveola assembly(GO:0070836)
0.0	1.6	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.6	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.0	0.2	GO:0048743	positive regulation of skeletal muscle fiber development(GO:0048743)
0.0	2.5	GO:0051703	social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0	1.0	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
0.0	0.9	GO:0034080	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0	0.0	GO:1990166	positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184) protein localization to site of double-strand break(GO:1990166)
0.0	0.3	GO:0044821	meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0	2.0	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.0	0.7	GO:0043496	regulation of protein homodimerization activity(GO:0043496)
0.0	1.0	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	2.7	GO:0030516	regulation of axon extension(GO:0030516)
0.0	0.1	GO:1903361	protein localization to basolateral plasma membrane(GO:1903361)
0.0	0.6	GO:0030033	microvillus assembly(GO:0030033)
0.0	0.3	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.0	0.5	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.3	GO:0043486	histone exchange(GO:0043486)
0.0	0.5	GO:0051895	negative regulation of focal adhesion assembly(GO:0051895) negative regulation of adherens junction organization(GO:1903392)
0.0	0.2	GO:0070933	histone H4 deacetylation(GO:0070933)
0.0	0.9	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.0	0.2	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0	0.1	GO:0021767	mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) positive regulation of lens fiber cell differentiation(GO:1902748)
0.0	0.1	GO:0009249	protein lipoylation(GO:0009249)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.2	25.8	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
4.9	19.7	GO:0097125	cyclin B1-CDK1 complex(GO:0097125)
3.6	14.3	GO:0000811	GINS complex(GO:0000811)
3.0	48.7	GO:0042555	MCM complex(GO:0042555)
1.6	9.4	GO:0008622	epsilon DNA polymerase complex(GO:0008622)
1.4	4.2	GO:0033593	BRCA2-MAGE-D1 complex(GO:0033593)
1.2	6.1	GO:0005873	plus-end kinesin complex(GO:0005873)
1.2	13.1	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
1.1	9.0	GO:0000796	condensin complex(GO:0000796)
1.1	10.0	GO:0031298	replication fork protection complex(GO:0031298)
1.0	4.9	GO:0032449	CBM complex(GO:0032449)
0.9	8.4	GO:0016012	sarcoglycan complex(GO:0016012)
0.7	2.8	GO:0033011	perinuclear theca(GO:0033011)
0.7	19.9	GO:0005720	nuclear heterochromatin(GO:0005720)
0.7	2.0	GO:0035189	Rb-E2F complex(GO:0035189)
0.6	11.7	GO:0045120	pronucleus(GO:0045120)
0.6	3.5	GO:0033553	rDNA heterochromatin(GO:0033553)
0.6	2.8	GO:0035061	interchromatin granule(GO:0035061)
0.5	11.8	GO:0005721	pericentric heterochromatin(GO:0005721)
0.5	10.3	GO:0000800	lateral element(GO:0000800)
0.5	4.5	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
0.4	2.4	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
0.4	7.7	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.3	5.5	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.3	2.0	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.3	1.9	GO:1990682	CSF1-CSF1R complex(GO:1990682)
0.3	2.2	GO:0098536	deuterosome(GO:0098536)
0.3	1.2	GO:1990075	periciliary membrane compartment(GO:1990075)
0.3	0.8	GO:0005663	DNA replication factor C complex(GO:0005663)
0.3	2.6	GO:0070552	BRISC complex(GO:0070552)
0.2	1.1	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.2	0.6	GO:0071149	TEAD-2-YAP complex(GO:0071149)
0.1	1.0	GO:0033503	HULC complex(GO:0033503)
0.1	0.9	GO:0034715	pICln-Sm protein complex(GO:0034715)
0.1	1.1	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
0.1	0.5	GO:0071942	XPC complex(GO:0071942)
0.1	7.7	GO:0043198	dendritic shaft(GO:0043198)
0.1	6.4	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.1	1.4	GO:0001673	male germ cell nucleus(GO:0001673)
0.1	6.1	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.1	2.8	GO:0051233	spindle midzone(GO:0051233)
0.1	0.2	GO:0005674	transcription factor TFIIF complex(GO:0005674)
0.1	2.9	GO:0005865	striated muscle thin filament(GO:0005865)
0.1	0.2	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.1	0.8	GO:0030015	CCR4-NOT core complex(GO:0030015)
0.1	0.9	GO:0071439	clathrin complex(GO:0071439)
0.0	10.1	GO:0048770	melanosome(GO:0042470) pigment granule(GO:0048770)
0.0	1.0	GO:0044232	organelle membrane contact site(GO:0044232)
0.0	0.2	GO:0030915	Smc5-Smc6 complex(GO:0030915)
0.0	24.8	GO:0005874	microtubule(GO:0005874)
0.0	6.2	GO:0005819	spindle(GO:0005819)
0.0	0.3	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.0	4.8	GO:0000776	kinetochore(GO:0000776)
0.0	0.4	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0	1.0	GO:0000795	synaptonemal complex(GO:0000795)
0.0	0.5	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.2	GO:0016589	NURF complex(GO:0016589)
0.0	13.4	GO:0005813	centrosome(GO:0005813)
0.0	0.9	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	1.4	GO:0072686	mitotic spindle(GO:0072686)
0.0	0.4	GO:0044815	DNA packaging complex(GO:0044815)
0.0	0.1	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0	2.9	GO:0030175	filopodium(GO:0030175)
0.0	1.4	GO:0000793	condensed chromosome(GO:0000793)
0.0	0.2	GO:0030014	CCR4-NOT complex(GO:0030014)
0.0	0.9	GO:0045171	intercellular bridge(GO:0045171)
0.0	0.1	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	7.3	GO:0005667	transcription factor complex(GO:0005667)
0.0	0.3	GO:0031229	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0	0.2	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.5	GO:0008180	COP9 signalosome(GO:0008180)
0.0	2.6	GO:0001726	ruffle(GO:0001726)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.2	25.8	GO:0016728	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
4.4	21.9	GO:0031493	nucleosomal histone binding(GO:0031493)
1.3	22.2	GO:0003688	DNA replication origin binding(GO:0003688)
1.2	3.5	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
1.1	4.5	GO:0004146	dihydrofolate reductase activity(GO:0004146)
1.1	14.3	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
1.0	3.0	GO:0004157	dihydropyrimidinase activity(GO:0004157)
1.0	15.0	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.9	19.7	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.9	7.7	GO:0035727	lysophosphatidic acid binding(GO:0035727)
0.7	10.2	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.7	30.4	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.6	4.2	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.6	10.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.5	6.4	GO:0004723	calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.4	2.6	GO:0004793	glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.4	0.8	GO:0030337	DNA polymerase processivity factor activity(GO:0030337)
0.4	2.4	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.3	11.8	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.3	3.5	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.3	1.9	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
0.2	1.9	GO:0000405	bubble DNA binding(GO:0000405)
0.2	0.7	GO:0045131	pre-mRNA branch point binding(GO:0045131)
0.2	3.3	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.2	1.7	GO:0008269	JAK pathway signal transduction adaptor activity(GO:0008269)
0.2	0.8	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.2	1.1	GO:0016748	succinyltransferase activity(GO:0016748)
0.2	2.1	GO:0051525	NFAT protein binding(GO:0051525)
0.1	1.0	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1	0.9	GO:0004137	deoxycytidine kinase activity(GO:0004137)
0.1	1.0	GO:0050733	RS domain binding(GO:0050733)
0.1	11.4	GO:0035064	methylated histone binding(GO:0035064)
0.1	0.6	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.1	5.0	GO:0043014	alpha-tubulin binding(GO:0043014)
0.1	2.7	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1	0.5	GO:1990226	histone methyltransferase binding(GO:1990226)
0.1	4.4	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.1	1.7	GO:0070182	DNA polymerase binding(GO:0070182)
0.1	0.8	GO:0004844	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.1	2.3	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.1	0.6	GO:0016531	copper chaperone activity(GO:0016531)
0.1	0.4	GO:0047288	monosialoganglioside sialyltransferase activity(GO:0047288)
0.1	0.3	GO:0061676	importin-alpha family protein binding(GO:0061676)
0.1	2.7	GO:0008519	ammonium transmembrane transporter activity(GO:0008519)
0.1	32.1	GO:0015631	tubulin binding(GO:0015631)
0.1	18.2	GO:0001047	core promoter binding(GO:0001047)
0.1	7.2	GO:0070491	repressing transcription factor binding(GO:0070491)
0.1	8.9	GO:0004386	helicase activity(GO:0004386)
0.1	1.9	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.1	0.3	GO:0048273	mitogen-activated protein kinase p38 binding(GO:0048273)
0.1	0.2	GO:0000150	recombinase activity(GO:0000150)
0.1	0.4	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.1	0.2	GO:0034046	poly(G) binding(GO:0034046)
0.0	2.8	GO:0050699	WW domain binding(GO:0050699)
0.0	0.4	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
0.0	6.4	GO:0042393	histone binding(GO:0042393)
0.0	0.6	GO:0001223	transcription coactivator binding(GO:0001223)
0.0	0.2	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.1	GO:0016534	cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.0	1.7	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.6	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.7	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
0.0	0.1	GO:0000035	acyl binding(GO:0000035)
0.0	0.6	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.3	GO:0008061	chitin binding(GO:0008061)
0.0	0.8	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	15.3	GO:0004842	ubiquitin-protein transferase activity(GO:0004842)
0.0	2.7	GO:0051087	chaperone binding(GO:0051087)
0.0	1.7	GO:0016763	transferase activity, transferring pentosyl groups(GO:0016763)
0.0	1.8	GO:0031072	heat shock protein binding(GO:0031072)
0.0	0.4	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.0	0.4	GO:0048038	quinone binding(GO:0048038)
0.0	1.9	GO:0017048	Rho GTPase binding(GO:0017048)
0.0	0.3	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.0	0.3	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.0	0.8	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.8	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0	1.0	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.7	24.5	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
1.4	28.2	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.6	38.6	PID ATR PATHWAY	ATR signaling pathway
0.3	39.5	PID E2F PATHWAY	E2F transcription factor network
0.2	4.9	PID FANCONI PATHWAY	Fanconi anemia pathway
0.2	6.1	PID MYC PATHWAY	C-MYC pathway
0.1	6.4	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.1	8.9	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.1	3.3	PID IL5 PATHWAY	IL5-mediated signaling events
0.1	9.5	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1	10.3	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.1	8.0	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.1	2.2	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.1	5.2	PID LKB1 PATHWAY	LKB1 signaling events
0.1	3.4	PID AURORA B PATHWAY	Aurora B signaling
0.1	1.3	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.1	1.9	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1	5.6	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	1.9	PID RHOA PATHWAY	RhoA signaling pathway
0.0	1.3	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.0	2.7	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	1.7	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.8	PID BARD1 PATHWAY	BARD1 signaling events
0.0	0.6	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.7	PID P53 REGULATION PATHWAY	p53 pathway
0.0	0.8	PID PLK1 PATHWAY	PLK1 signaling events
0.0	0.7	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.7	62.7	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
2.3	69.3	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
1.3	15.4	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
1.1	17.0	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.9	33.5	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.5	7.3	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.2	5.5	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.2	5.2	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.2	10.1	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.2	1.3	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.2	8.9	REACTOME G1 PHASE	Genes involved in G1 Phase
0.2	6.1	REACTOME KINESINS	Genes involved in Kinesins
0.1	1.1	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.1	3.0	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	2.1	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.1	1.0	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.8	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	1.1	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.9	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.9	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	2.7	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	1.6	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	7.4	REACTOME G ALPHA Q SIGNALLING EVENTS	Genes involved in G alpha (q) signalling events
0.0	1.0	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.6	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.5	REACTOME RNA POL I TRANSCRIPTION	Genes involved in RNA Polymerase I Transcription
0.0	0.4	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	3.7	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	1.4	REACTOME LATE PHASE OF HIV LIFE CYCLE	Genes involved in Late Phase of HIV Life Cycle
0.0	0.1	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	0.8	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels

Results for E2F2_E2F5

Z-value: 2.31

Motif logo

Transcription factors associated with E2F2_E2F5

Activity-expression correlation:

Activity profile of E2F2_E2F5 motif

Sorted Z-values of E2F2_E2F5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of E2F2_E2F5

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: