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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)
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Results for E2F7_E2F1
Z-value: 3.39
Motif logo
Transcription factors associated with E2F7_E2F1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
E2F7
|
ENSG00000165891.16 | E2F7 |
|
E2F1
|
ENSG00000101412.13 | E2F1 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| E2F7 | hg38_v1_chr12_-_77065526_77065586 | 0.73 | 4.2e-06 | Click! |
| E2F1 | hg38_v1_chr20_-_33686371_33686407 | 0.50 | 4.5e-03 | Click! |
Activity profile of E2F7_E2F1 motif
Sorted Z-values of E2F7_E2F1 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of E2F7_E2F1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 7.9 | 23.8 | GO:0036333 | hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772) |
| 7.8 | 23.4 | GO:0032877 | positive regulation of DNA endoreduplication(GO:0032877) |
| 4.4 | 13.1 | GO:0031508 | pericentric heterochromatin assembly(GO:0031508) |
| 4.3 | 34.3 | GO:0000727 | double-strand break repair via break-induced replication(GO:0000727) |
| 3.9 | 19.6 | GO:0019087 | transformation of host cell by virus(GO:0019087) uracil metabolic process(GO:0019860) |
| 3.8 | 11.3 | GO:0070510 | regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512) |
| 3.2 | 28.6 | GO:0010216 | maintenance of DNA methylation(GO:0010216) |
| 3.1 | 40.9 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 3.1 | 18.8 | GO:0033567 | DNA replication, Okazaki fragment processing(GO:0033567) |
| 3.0 | 12.2 | GO:0035407 | histone H3-T11 phosphorylation(GO:0035407) |
| 2.8 | 11.2 | GO:1990918 | meiotic DNA double-strand break processing(GO:0000706) double-strand break repair involved in meiotic recombination(GO:1990918) |
| 2.3 | 13.9 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 2.2 | 15.5 | GO:0006269 | DNA replication, synthesis of RNA primer(GO:0006269) |
| 2.0 | 6.0 | GO:0010520 | regulation of reciprocal meiotic recombination(GO:0010520) |
| 1.9 | 13.6 | GO:1900262 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
| 1.8 | 5.4 | GO:0008614 | pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 biosynthetic process(GO:0042819) |
| 1.8 | 5.3 | GO:0046452 | dihydrofolate metabolic process(GO:0046452) |
| 1.4 | 5.5 | GO:1904116 | response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117) |
| 1.3 | 35.1 | GO:0009263 | deoxyribonucleotide biosynthetic process(GO:0009263) |
| 1.3 | 11.5 | GO:0009157 | deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) |
| 1.2 | 2.4 | GO:1990166 | protein localization to site of double-strand break(GO:1990166) |
| 1.0 | 10.4 | GO:0061087 | positive regulation of histone H3-K27 methylation(GO:0061087) |
| 1.0 | 3.0 | GO:0018312 | peptidyl-serine ADP-ribosylation(GO:0018312) |
| 1.0 | 4.0 | GO:0009786 | regulation of asymmetric cell division(GO:0009786) |
| 1.0 | 5.0 | GO:2000327 | regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327) |
| 1.0 | 7.9 | GO:0090166 | Golgi disassembly(GO:0090166) |
| 1.0 | 1.9 | GO:0009136 | ADP biosynthetic process(GO:0006172) nucleoside diphosphate biosynthetic process(GO:0009133) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188) |
| 1.0 | 2.9 | GO:1902595 | regulation of DNA replication origin binding(GO:1902595) |
| 1.0 | 2.9 | GO:0071373 | cellular response to cocaine(GO:0071314) cellular response to luteinizing hormone stimulus(GO:0071373) |
| 0.9 | 2.7 | GO:1901069 | guanosine-containing compound catabolic process(GO:1901069) |
| 0.9 | 2.6 | GO:0006287 | base-excision repair, gap-filling(GO:0006287) |
| 0.8 | 0.8 | GO:0061153 | trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) |
| 0.8 | 2.5 | GO:0018160 | peptidyl-pyrromethane cofactor linkage(GO:0018160) |
| 0.8 | 2.5 | GO:0045014 | carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) |
| 0.8 | 3.3 | GO:0034421 | post-translational protein acetylation(GO:0034421) |
| 0.8 | 2.5 | GO:0070650 | endoplasmic reticulum polarization(GO:0061163) actin filament bundle retrograde transport(GO:0061573) actin filament bundle distribution(GO:0070650) |
| 0.8 | 5.5 | GO:0006335 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.8 | 10.8 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 0.8 | 2.3 | GO:0075732 | viral penetration into host nucleus(GO:0075732) multi-organism nuclear import(GO:1902594) |
| 0.7 | 7.9 | GO:0007076 | mitotic chromosome condensation(GO:0007076) |
| 0.7 | 8.6 | GO:0000733 | DNA strand renaturation(GO:0000733) |
| 0.7 | 1.4 | GO:0006272 | leading strand elongation(GO:0006272) |
| 0.7 | 2.1 | GO:0061184 | positive regulation of dermatome development(GO:0061184) |
| 0.7 | 26.0 | GO:0006270 | DNA replication initiation(GO:0006270) |
| 0.7 | 2.1 | GO:1901254 | modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254) |
| 0.7 | 27.5 | GO:0031116 | positive regulation of microtubule polymerization(GO:0031116) |
| 0.7 | 7.9 | GO:0051103 | DNA ligation involved in DNA repair(GO:0051103) |
| 0.7 | 27.0 | GO:0034080 | chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) |
| 0.7 | 3.3 | GO:1904636 | response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637) |
| 0.7 | 3.3 | GO:0046391 | 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391) |
| 0.6 | 3.2 | GO:0097021 | Peyer's patch morphogenesis(GO:0061146) lymphocyte migration into lymphoid organs(GO:0097021) |
| 0.6 | 5.7 | GO:0006189 | 'de novo' IMP biosynthetic process(GO:0006189) |
| 0.6 | 5.0 | GO:0006271 | DNA strand elongation involved in DNA replication(GO:0006271) |
| 0.6 | 2.4 | GO:0031161 | phosphatidylinositol catabolic process(GO:0031161) |
| 0.6 | 1.8 | GO:0043465 | fermentation(GO:0006113) regulation of fermentation(GO:0043465) |
| 0.6 | 15.1 | GO:0000732 | strand displacement(GO:0000732) |
| 0.6 | 2.3 | GO:2000685 | mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) oncogene-induced cell senescence(GO:0090402) positive regulation of cellular response to X-ray(GO:2000685) |
| 0.6 | 4.6 | GO:0033504 | floor plate development(GO:0033504) |
| 0.6 | 2.2 | GO:0010982 | regulation of high-density lipoprotein particle clearance(GO:0010982) |
| 0.5 | 0.5 | GO:0071630 | nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630) |
| 0.5 | 1.0 | GO:0043504 | mitochondrial DNA repair(GO:0043504) |
| 0.5 | 4.1 | GO:0048014 | Tie signaling pathway(GO:0048014) |
| 0.5 | 1.5 | GO:1902490 | regulation of sperm capacitation(GO:1902490) |
| 0.5 | 1.5 | GO:0000710 | meiotic mismatch repair(GO:0000710) |
| 0.5 | 2.9 | GO:0070086 | ubiquitin-dependent endocytosis(GO:0070086) |
| 0.5 | 1.4 | GO:0046108 | uridine metabolic process(GO:0046108) |
| 0.5 | 1.4 | GO:0044205 | 'de novo' UMP biosynthetic process(GO:0044205) |
| 0.5 | 1.4 | GO:0006421 | asparaginyl-tRNA aminoacylation(GO:0006421) |
| 0.5 | 2.3 | GO:0006290 | pyrimidine dimer repair(GO:0006290) |
| 0.4 | 3.1 | GO:0072711 | cellular response to hydroxyurea(GO:0072711) |
| 0.4 | 1.7 | GO:0044313 | protein K6-linked deubiquitination(GO:0044313) |
| 0.4 | 1.3 | GO:0072579 | molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579) |
| 0.4 | 4.2 | GO:0031936 | negative regulation of chromatin silencing(GO:0031936) |
| 0.4 | 2.4 | GO:0071460 | cellular response to cell-matrix adhesion(GO:0071460) |
| 0.4 | 1.2 | GO:1904956 | regulation of midbrain dopaminergic neuron differentiation(GO:1904956) |
| 0.4 | 1.2 | GO:2000830 | vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830) |
| 0.4 | 1.6 | GO:0009257 | 10-formyltetrahydrofolate biosynthetic process(GO:0009257) |
| 0.4 | 1.6 | GO:1904744 | positive regulation of telomeric DNA binding(GO:1904744) |
| 0.4 | 5.3 | GO:2001032 | regulation of double-strand break repair via nonhomologous end joining(GO:2001032) |
| 0.4 | 3.4 | GO:2000042 | negative regulation of double-strand break repair via homologous recombination(GO:2000042) |
| 0.4 | 1.9 | GO:0033512 | L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512) |
| 0.4 | 1.1 | GO:1904395 | positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) |
| 0.4 | 1.4 | GO:0018242 | protein O-linked glycosylation via serine(GO:0018242) |
| 0.4 | 1.1 | GO:0034476 | U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) |
| 0.4 | 15.2 | GO:0036297 | interstrand cross-link repair(GO:0036297) |
| 0.3 | 2.3 | GO:0001661 | conditioned taste aversion(GO:0001661) |
| 0.3 | 0.7 | GO:0051097 | negative regulation of helicase activity(GO:0051097) |
| 0.3 | 3.9 | GO:0021943 | formation of radial glial scaffolds(GO:0021943) |
| 0.3 | 3.2 | GO:0048102 | autophagic cell death(GO:0048102) |
| 0.3 | 1.3 | GO:1903070 | negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) |
| 0.3 | 4.1 | GO:0071459 | protein localization to chromosome, centromeric region(GO:0071459) |
| 0.3 | 0.9 | GO:0007308 | oocyte construction(GO:0007308) oocyte axis specification(GO:0007309) oocyte anterior/posterior axis specification(GO:0007314) pole plasm assembly(GO:0007315) maternal determination of anterior/posterior axis, embryo(GO:0008358) P granule organization(GO:0030719) |
| 0.3 | 7.7 | GO:0007250 | activation of NF-kappaB-inducing kinase activity(GO:0007250) |
| 0.3 | 0.9 | GO:0008355 | olfactory learning(GO:0008355) |
| 0.3 | 1.5 | GO:0046167 | glycerol-3-phosphate biosynthetic process(GO:0046167) |
| 0.3 | 3.6 | GO:0031297 | replication fork processing(GO:0031297) |
| 0.3 | 3.0 | GO:0070494 | regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) |
| 0.3 | 0.9 | GO:0043006 | activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006) |
| 0.3 | 0.9 | GO:0045875 | negative regulation of sister chromatid cohesion(GO:0045875) |
| 0.3 | 1.7 | GO:0035105 | sterol regulatory element binding protein import into nucleus(GO:0035105) |
| 0.3 | 2.3 | GO:0051415 | interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418) |
| 0.3 | 1.1 | GO:1903971 | positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141) |
| 0.3 | 1.7 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
| 0.3 | 0.3 | GO:0098905 | regulation of bundle of His cell action potential(GO:0098905) |
| 0.3 | 3.1 | GO:0007135 | meiosis II(GO:0007135) |
| 0.3 | 1.1 | GO:1904980 | positive regulation of endosome organization(GO:1904980) |
| 0.3 | 0.8 | GO:0045082 | interleukin-13 biosynthetic process(GO:0042231) positive regulation of interleukin-10 biosynthetic process(GO:0045082) |
| 0.3 | 0.6 | GO:0060061 | Spemann organizer formation(GO:0060061) |
| 0.3 | 3.2 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 0.3 | 0.8 | GO:0014707 | branchiomeric skeletal muscle development(GO:0014707) |
| 0.3 | 1.3 | GO:0034334 | adherens junction maintenance(GO:0034334) |
| 0.3 | 3.1 | GO:0060236 | regulation of mitotic spindle organization(GO:0060236) |
| 0.3 | 2.0 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
| 0.3 | 2.3 | GO:0046604 | positive regulation of mitotic centrosome separation(GO:0046604) |
| 0.3 | 1.5 | GO:0043418 | homocysteine catabolic process(GO:0043418) |
| 0.3 | 4.3 | GO:1904776 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
| 0.2 | 1.5 | GO:0006065 | UDP-glucuronate biosynthetic process(GO:0006065) |
| 0.2 | 14.2 | GO:0019985 | translesion synthesis(GO:0019985) |
| 0.2 | 0.7 | GO:0034653 | diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653) regulation of skeletal muscle fiber differentiation(GO:1902809) |
| 0.2 | 1.0 | GO:0021592 | fourth ventricle development(GO:0021592) |
| 0.2 | 1.2 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
| 0.2 | 0.7 | GO:2000562 | negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562) |
| 0.2 | 0.5 | GO:0071140 | resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140) |
| 0.2 | 1.9 | GO:0016560 | protein import into peroxisome matrix, docking(GO:0016560) |
| 0.2 | 1.4 | GO:0002329 | pre-B cell differentiation(GO:0002329) |
| 0.2 | 3.6 | GO:0000050 | urea cycle(GO:0000050) |
| 0.2 | 2.3 | GO:0060296 | regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019) |
| 0.2 | 1.3 | GO:0035617 | stress granule disassembly(GO:0035617) |
| 0.2 | 0.2 | GO:0060978 | angiogenesis involved in coronary vascular morphogenesis(GO:0060978) |
| 0.2 | 1.1 | GO:0006543 | glutamine catabolic process(GO:0006543) |
| 0.2 | 1.3 | GO:1903566 | positive regulation of protein localization to cilium(GO:1903566) |
| 0.2 | 1.7 | GO:0072526 | pyridine-containing compound catabolic process(GO:0072526) |
| 0.2 | 0.8 | GO:1901165 | positive regulation of trophoblast cell migration(GO:1901165) |
| 0.2 | 0.4 | GO:1904616 | regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616) |
| 0.2 | 1.0 | GO:0051013 | microtubule severing(GO:0051013) |
| 0.2 | 1.6 | GO:0015705 | iodide transport(GO:0015705) |
| 0.2 | 1.0 | GO:0060373 | regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373) |
| 0.2 | 1.2 | GO:0033603 | positive regulation of dopamine secretion(GO:0033603) |
| 0.2 | 2.0 | GO:0007217 | tachykinin receptor signaling pathway(GO:0007217) |
| 0.2 | 0.8 | GO:0086021 | SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021) |
| 0.2 | 0.2 | GO:0098532 | histone H3-K27 trimethylation(GO:0098532) |
| 0.2 | 3.2 | GO:0031573 | intra-S DNA damage checkpoint(GO:0031573) |
| 0.2 | 0.8 | GO:0002501 | peptide antigen assembly with MHC protein complex(GO:0002501) |
| 0.2 | 1.0 | GO:0030035 | microspike assembly(GO:0030035) |
| 0.2 | 3.5 | GO:1903504 | regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504) |
| 0.2 | 2.1 | GO:1904996 | positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996) |
| 0.2 | 4.3 | GO:0033260 | nuclear DNA replication(GO:0033260) |
| 0.2 | 0.6 | GO:0055014 | atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014) |
| 0.2 | 0.6 | GO:1901355 | response to rapamycin(GO:1901355) |
| 0.2 | 0.6 | GO:0019287 | isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) |
| 0.2 | 0.8 | GO:2000781 | positive regulation of double-strand break repair(GO:2000781) |
| 0.2 | 1.7 | GO:0007023 | post-chaperonin tubulin folding pathway(GO:0007023) |
| 0.2 | 1.5 | GO:0001866 | NK T cell proliferation(GO:0001866) |
| 0.2 | 0.6 | GO:1903527 | positive regulation of membrane tubulation(GO:1903527) |
| 0.2 | 2.2 | GO:0098535 | de novo centriole assembly(GO:0098535) |
| 0.2 | 0.7 | GO:1903860 | negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173) |
| 0.2 | 12.0 | GO:0032465 | regulation of cytokinesis(GO:0032465) |
| 0.2 | 2.0 | GO:0043985 | histone H4-R3 methylation(GO:0043985) |
| 0.2 | 0.5 | GO:0002582 | positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588) |
| 0.2 | 1.4 | GO:0034724 | DNA replication-independent nucleosome organization(GO:0034724) |
| 0.2 | 0.5 | GO:0000103 | sulfate assimilation(GO:0000103) |
| 0.2 | 0.7 | GO:0046947 | hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947) |
| 0.2 | 0.9 | GO:0007343 | egg activation(GO:0007343) |
| 0.2 | 8.1 | GO:0051225 | spindle assembly(GO:0051225) |
| 0.2 | 0.5 | GO:0070078 | peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine(GO:0018395) histone arginine demethylation(GO:0070077) histone H3-R2 demethylation(GO:0070078) histone H4-R3 demethylation(GO:0070079) |
| 0.2 | 12.0 | GO:0090307 | mitotic spindle assembly(GO:0090307) |
| 0.2 | 17.2 | GO:0071349 | interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349) |
| 0.2 | 0.9 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
| 0.2 | 1.9 | GO:1902902 | negative regulation of autophagosome assembly(GO:1902902) |
| 0.2 | 1.7 | GO:0060700 | regulation of ribonuclease activity(GO:0060700) |
| 0.2 | 3.3 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
| 0.2 | 0.5 | GO:2000297 | negative regulation of synapse maturation(GO:2000297) |
| 0.2 | 3.4 | GO:0000920 | cell separation after cytokinesis(GO:0000920) |
| 0.2 | 0.5 | GO:1903939 | regulation of TORC2 signaling(GO:1903939) |
| 0.2 | 1.2 | GO:0006777 | Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) |
| 0.2 | 1.0 | GO:0007386 | compartment pattern specification(GO:0007386) |
| 0.2 | 0.5 | GO:0050717 | positive regulation of interleukin-1 alpha secretion(GO:0050717) |
| 0.2 | 3.5 | GO:0051310 | metaphase plate congression(GO:0051310) |
| 0.2 | 0.8 | GO:0070127 | tRNA aminoacylation for mitochondrial protein translation(GO:0070127) |
| 0.2 | 1.8 | GO:0006301 | postreplication repair(GO:0006301) |
| 0.2 | 4.2 | GO:0050774 | negative regulation of dendrite morphogenesis(GO:0050774) |
| 0.2 | 0.5 | GO:1904640 | cellular response to potassium ion starvation(GO:0051365) response to methionine(GO:1904640) |
| 0.2 | 0.9 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
| 0.2 | 1.3 | GO:0000183 | chromatin silencing at rDNA(GO:0000183) |
| 0.2 | 0.3 | GO:0090071 | negative regulation of ribosome biogenesis(GO:0090071) |
| 0.2 | 2.6 | GO:0001542 | ovulation from ovarian follicle(GO:0001542) |
| 0.2 | 3.5 | GO:0055003 | cardiac myofibril assembly(GO:0055003) |
| 0.2 | 0.6 | GO:2000843 | testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845) |
| 0.2 | 0.5 | GO:0072244 | metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313) |
| 0.1 | 6.1 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 0.1 | 0.4 | GO:1902269 | positive regulation of polyamine transmembrane transport(GO:1902269) |
| 0.1 | 0.6 | GO:0010430 | fatty acid omega-oxidation(GO:0010430) |
| 0.1 | 0.7 | GO:1904491 | protein localization to ciliary transition zone(GO:1904491) |
| 0.1 | 0.4 | GO:0050976 | detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) |
| 0.1 | 1.7 | GO:2000628 | regulation of miRNA metabolic process(GO:2000628) |
| 0.1 | 1.6 | GO:1904936 | cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936) |
| 0.1 | 0.4 | GO:0090222 | centrosome-templated microtubule nucleation(GO:0090222) |
| 0.1 | 0.4 | GO:0021503 | neural fold bending(GO:0021503) |
| 0.1 | 0.7 | GO:0097411 | hypoxia-inducible factor-1alpha signaling pathway(GO:0097411) |
| 0.1 | 1.8 | GO:0070431 | nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431) |
| 0.1 | 0.4 | GO:0009186 | dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) deoxyribonucleoside diphosphate metabolic process(GO:0009186) purine deoxyribonucleoside triphosphate biosynthetic process(GO:0009216) dADP metabolic process(GO:0046056) dGDP metabolic process(GO:0046066) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571) |
| 0.1 | 0.9 | GO:0016926 | protein desumoylation(GO:0016926) |
| 0.1 | 0.4 | GO:1901073 | N-acetylglucosamine biosynthetic process(GO:0006045) glucosamine-containing compound biosynthetic process(GO:1901073) |
| 0.1 | 2.6 | GO:0030497 | fatty acid elongation(GO:0030497) |
| 0.1 | 0.8 | GO:0090669 | snRNA pseudouridine synthesis(GO:0031120) telomerase RNA stabilization(GO:0090669) |
| 0.1 | 0.3 | GO:0036496 | regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496) |
| 0.1 | 0.6 | GO:0051643 | endoplasmic reticulum localization(GO:0051643) |
| 0.1 | 0.5 | GO:0045653 | negative regulation of megakaryocyte differentiation(GO:0045653) |
| 0.1 | 0.8 | GO:0015853 | adenine transport(GO:0015853) |
| 0.1 | 3.4 | GO:0032515 | negative regulation of phosphoprotein phosphatase activity(GO:0032515) |
| 0.1 | 1.1 | GO:0035087 | siRNA loading onto RISC involved in RNA interference(GO:0035087) |
| 0.1 | 0.4 | GO:0051463 | negative regulation of cortisol secretion(GO:0051463) negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850) |
| 0.1 | 0.5 | GO:0090156 | cellular sphingolipid homeostasis(GO:0090156) |
| 0.1 | 0.2 | GO:0031064 | negative regulation of histone deacetylation(GO:0031064) |
| 0.1 | 2.1 | GO:0042789 | mRNA transcription from RNA polymerase II promoter(GO:0042789) |
| 0.1 | 0.9 | GO:0097105 | presynaptic membrane assembly(GO:0097105) |
| 0.1 | 0.3 | GO:0035720 | intraciliary anterograde transport(GO:0035720) |
| 0.1 | 0.3 | GO:0034729 | histone H3-K79 methylation(GO:0034729) |
| 0.1 | 0.8 | GO:0042078 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
| 0.1 | 0.3 | GO:0038162 | erythropoietin-mediated signaling pathway(GO:0038162) |
| 0.1 | 5.9 | GO:0043044 | ATP-dependent chromatin remodeling(GO:0043044) |
| 0.1 | 0.3 | GO:0030974 | thiamine pyrophosphate transport(GO:0030974) |
| 0.1 | 0.2 | GO:2000538 | regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538) |
| 0.1 | 1.5 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 0.1 | 0.5 | GO:0042986 | positive regulation of amyloid precursor protein biosynthetic process(GO:0042986) |
| 0.1 | 2.1 | GO:0035020 | regulation of Rac protein signal transduction(GO:0035020) |
| 0.1 | 0.2 | GO:1903626 | positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626) |
| 0.1 | 1.4 | GO:0043249 | erythrocyte maturation(GO:0043249) |
| 0.1 | 0.3 | GO:1902309 | regulation of heart rate by hormone(GO:0003064) negative regulation of peptidyl-serine dephosphorylation(GO:1902309) |
| 0.1 | 0.9 | GO:0000972 | transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972) |
| 0.1 | 0.5 | GO:0030579 | ubiquitin-dependent SMAD protein catabolic process(GO:0030579) |
| 0.1 | 0.3 | GO:0007228 | signal transduction downstream of smoothened(GO:0007227) positive regulation of hh target transcription factor activity(GO:0007228) |
| 0.1 | 1.3 | GO:0070050 | neuron cellular homeostasis(GO:0070050) |
| 0.1 | 0.3 | GO:0006579 | amino-acid betaine catabolic process(GO:0006579) |
| 0.1 | 1.9 | GO:0071493 | cellular response to UV-B(GO:0071493) |
| 0.1 | 0.2 | GO:0014028 | notochord formation(GO:0014028) axial mesoderm formation(GO:0048320) |
| 0.1 | 0.4 | GO:0060282 | positive regulation of oocyte development(GO:0060282) |
| 0.1 | 0.9 | GO:0033564 | anterior/posterior axon guidance(GO:0033564) |
| 0.1 | 3.5 | GO:0007019 | microtubule depolymerization(GO:0007019) |
| 0.1 | 0.4 | GO:0048254 | snoRNA localization(GO:0048254) |
| 0.1 | 0.4 | GO:0051866 | general adaptation syndrome(GO:0051866) |
| 0.1 | 2.5 | GO:0071539 | protein localization to centrosome(GO:0071539) |
| 0.1 | 0.8 | GO:0071173 | mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173) |
| 0.1 | 0.6 | GO:1903588 | regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588) |
| 0.1 | 1.7 | GO:0007097 | nuclear migration(GO:0007097) |
| 0.1 | 0.5 | GO:2000110 | negative regulation of macrophage apoptotic process(GO:2000110) |
| 0.1 | 0.7 | GO:0048539 | bone marrow development(GO:0048539) |
| 0.1 | 1.2 | GO:0034720 | histone H3-K4 demethylation(GO:0034720) |
| 0.1 | 0.6 | GO:1902856 | negative regulation of nonmotile primary cilium assembly(GO:1902856) |
| 0.1 | 0.8 | GO:0002667 | lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) |
| 0.1 | 2.3 | GO:0051764 | actin crosslink formation(GO:0051764) |
| 0.1 | 0.3 | GO:0051793 | medium-chain fatty acid catabolic process(GO:0051793) |
| 0.1 | 1.6 | GO:0060732 | positive regulation of inositol phosphate biosynthetic process(GO:0060732) |
| 0.1 | 1.4 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
| 0.1 | 0.6 | GO:0035372 | protein localization to microtubule(GO:0035372) |
| 0.1 | 0.4 | GO:0032902 | nerve growth factor production(GO:0032902) |
| 0.1 | 2.8 | GO:0071431 | tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431) |
| 0.1 | 0.8 | GO:0034244 | negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244) |
| 0.1 | 0.9 | GO:2000601 | positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601) |
| 0.1 | 0.5 | GO:0009048 | dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048) |
| 0.1 | 1.2 | GO:0044065 | regulation of respiratory system process(GO:0044065) |
| 0.1 | 0.3 | GO:0098746 | fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746) |
| 0.1 | 0.3 | GO:0003363 | lamellipodium assembly involved in ameboidal cell migration(GO:0003363) |
| 0.1 | 1.3 | GO:0060174 | limb bud formation(GO:0060174) |
| 0.1 | 1.1 | GO:0015939 | pantothenate metabolic process(GO:0015939) |
| 0.1 | 0.4 | GO:0003164 | His-Purkinje system development(GO:0003164) |
| 0.1 | 0.7 | GO:0035879 | plasma membrane lactate transport(GO:0035879) |
| 0.1 | 0.4 | GO:0006788 | heme oxidation(GO:0006788) |
| 0.1 | 1.3 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
| 0.1 | 0.2 | GO:0070842 | aggresome assembly(GO:0070842) |
| 0.1 | 0.7 | GO:0070836 | caveola assembly(GO:0070836) |
| 0.1 | 0.8 | GO:2000252 | negative regulation of feeding behavior(GO:2000252) |
| 0.1 | 1.8 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 0.1 | 1.6 | GO:0040015 | negative regulation of multicellular organism growth(GO:0040015) |
| 0.1 | 0.2 | GO:0061502 | early endosome to recycling endosome transport(GO:0061502) |
| 0.1 | 0.7 | GO:1902855 | nonmotile primary cilium assembly(GO:0035058) regulation of nonmotile primary cilium assembly(GO:1902855) positive regulation of nonmotile primary cilium assembly(GO:1902857) |
| 0.1 | 0.2 | GO:0032811 | negative regulation of epinephrine secretion(GO:0032811) |
| 0.1 | 0.6 | GO:1900748 | positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) |
| 0.1 | 0.2 | GO:0006011 | UDP-glucose metabolic process(GO:0006011) |
| 0.1 | 0.3 | GO:0007206 | phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206) |
| 0.1 | 0.5 | GO:0019236 | response to pheromone(GO:0019236) |
| 0.1 | 1.3 | GO:0043248 | proteasome assembly(GO:0043248) |
| 0.1 | 0.5 | GO:0048295 | positive regulation of isotype switching to IgE isotypes(GO:0048295) |
| 0.1 | 0.5 | GO:0036484 | trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) neural crest cell migration involved in autonomic nervous system development(GO:1901166) |
| 0.1 | 0.2 | GO:0006106 | fumarate metabolic process(GO:0006106) |
| 0.1 | 0.1 | GO:1901420 | negative regulation of response to alcohol(GO:1901420) |
| 0.1 | 0.1 | GO:1902824 | positive regulation of late endosome to lysosome transport(GO:1902824) |
| 0.1 | 0.6 | GO:0042532 | negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532) |
| 0.1 | 1.2 | GO:0070986 | left/right axis specification(GO:0070986) |
| 0.1 | 0.6 | GO:0042256 | mature ribosome assembly(GO:0042256) |
| 0.1 | 0.5 | GO:2000230 | response to metformin(GO:1901558) negative regulation of pancreatic stellate cell proliferation(GO:2000230) |
| 0.1 | 0.1 | GO:0033484 | nitric oxide homeostasis(GO:0033484) |
| 0.1 | 0.2 | GO:0021722 | pons maturation(GO:0021586) superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722) |
| 0.1 | 0.5 | GO:1904879 | positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879) |
| 0.1 | 0.4 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
| 0.1 | 0.2 | GO:0048631 | regulation of skeletal muscle tissue growth(GO:0048631) |
| 0.1 | 0.3 | GO:0060040 | retinal bipolar neuron differentiation(GO:0060040) |
| 0.1 | 0.3 | GO:0071386 | cellular response to corticosterone stimulus(GO:0071386) |
| 0.1 | 0.3 | GO:1902559 | 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559) |
| 0.1 | 0.6 | GO:0021633 | optic nerve structural organization(GO:0021633) |
| 0.1 | 0.2 | GO:0071947 | protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) |
| 0.1 | 0.5 | GO:0071233 | cellular response to leucine(GO:0071233) |
| 0.1 | 0.9 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
| 0.1 | 0.6 | GO:0036444 | calcium ion transmembrane import into mitochondrion(GO:0036444) |
| 0.1 | 0.7 | GO:0035095 | behavioral response to nicotine(GO:0035095) |
| 0.1 | 0.2 | GO:0061073 | ciliary body morphogenesis(GO:0061073) |
| 0.1 | 0.8 | GO:0051412 | response to corticosterone(GO:0051412) |
| 0.1 | 0.6 | GO:0097033 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033) |
| 0.1 | 0.5 | GO:0000389 | mRNA 3'-splice site recognition(GO:0000389) |
| 0.1 | 0.5 | GO:0008215 | spermine metabolic process(GO:0008215) |
| 0.1 | 0.3 | GO:0060800 | regulation of cell differentiation involved in embryonic placenta development(GO:0060800) |
| 0.1 | 1.0 | GO:0031468 | nuclear envelope reassembly(GO:0031468) |
| 0.1 | 0.3 | GO:0003199 | endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) |
| 0.1 | 0.3 | GO:0003356 | regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356) |
| 0.1 | 0.3 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 0.1 | 0.2 | GO:0035425 | autocrine signaling(GO:0035425) |
| 0.1 | 0.2 | GO:2001247 | positive regulation of phosphatidylcholine biosynthetic process(GO:2001247) |
| 0.1 | 0.5 | GO:0034465 | response to carbon monoxide(GO:0034465) |
| 0.1 | 0.3 | GO:0018352 | protein-pyridoxal-5-phosphate linkage(GO:0018352) |
| 0.1 | 0.2 | GO:0030047 | actin modification(GO:0030047) |
| 0.1 | 0.4 | GO:0031584 | activation of phospholipase D activity(GO:0031584) |
| 0.1 | 0.3 | GO:2000035 | regulation of stem cell division(GO:2000035) |
| 0.1 | 0.9 | GO:0043518 | negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) |
| 0.1 | 0.4 | GO:0021869 | forebrain ventricular zone progenitor cell division(GO:0021869) |
| 0.1 | 1.4 | GO:0009649 | entrainment of circadian clock(GO:0009649) |
| 0.1 | 0.8 | GO:0016601 | Rac protein signal transduction(GO:0016601) |
| 0.1 | 2.5 | GO:0035329 | hippo signaling(GO:0035329) |
| 0.1 | 0.4 | GO:0006013 | mannose metabolic process(GO:0006013) |
| 0.1 | 0.3 | GO:0000012 | single strand break repair(GO:0000012) |
| 0.1 | 0.7 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.0 | 0.6 | GO:0044351 | macropinocytosis(GO:0044351) |
| 0.0 | 0.3 | GO:0039663 | fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800) |
| 0.0 | 1.0 | GO:2000810 | regulation of bicellular tight junction assembly(GO:2000810) |
| 0.0 | 0.5 | GO:2000795 | negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
| 0.0 | 2.2 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
| 0.0 | 0.6 | GO:0009650 | UV protection(GO:0009650) |
| 0.0 | 0.2 | GO:0045876 | positive regulation of sister chromatid cohesion(GO:0045876) |
| 0.0 | 0.5 | GO:0001675 | acrosome assembly(GO:0001675) |
| 0.0 | 0.5 | GO:2000172 | regulation of branching morphogenesis of a nerve(GO:2000172) |
| 0.0 | 0.3 | GO:0061143 | alveolar primary septum development(GO:0061143) paramesonephric duct development(GO:0061205) |
| 0.0 | 0.4 | GO:0043654 | recognition of apoptotic cell(GO:0043654) |
| 0.0 | 0.2 | GO:0044240 | multicellular organism lipid catabolic process(GO:0044240) |
| 0.0 | 0.4 | GO:0001915 | negative regulation of T cell mediated cytotoxicity(GO:0001915) |
| 0.0 | 0.1 | GO:0032482 | Rab protein signal transduction(GO:0032482) |
| 0.0 | 0.2 | GO:0019075 | virus maturation(GO:0019075) |
| 0.0 | 0.3 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
| 0.0 | 0.1 | GO:1900154 | regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155) |
| 0.0 | 0.1 | GO:0006059 | hexitol metabolic process(GO:0006059) |
| 0.0 | 3.2 | GO:0033275 | muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275) |
| 0.0 | 0.3 | GO:0043576 | regulation of respiratory gaseous exchange(GO:0043576) |
| 0.0 | 0.5 | GO:1904261 | regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197) |
| 0.0 | 0.3 | GO:1905247 | positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) positive regulation of aspartic-type peptidase activity(GO:1905247) |
| 0.0 | 0.8 | GO:0014733 | regulation of skeletal muscle adaptation(GO:0014733) |
| 0.0 | 3.9 | GO:0030516 | regulation of axon extension(GO:0030516) |
| 0.0 | 0.2 | GO:0089700 | protein kinase D signaling(GO:0089700) |
| 0.0 | 0.1 | GO:2000051 | negative regulation of non-canonical Wnt signaling pathway(GO:2000051) |
| 0.0 | 1.0 | GO:0034389 | lipid particle organization(GO:0034389) |
| 0.0 | 0.0 | GO:0070898 | RNA polymerase III transcriptional preinitiation complex assembly(GO:0070898) |
| 0.0 | 0.2 | GO:0042853 | L-alanine metabolic process(GO:0042851) L-alanine catabolic process(GO:0042853) |
| 0.0 | 0.2 | GO:0072299 | adrenal cortex development(GO:0035801) adrenal cortex formation(GO:0035802) negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302) |
| 0.0 | 0.9 | GO:0001829 | trophectodermal cell differentiation(GO:0001829) |
| 0.0 | 1.2 | GO:0014850 | response to muscle activity(GO:0014850) |
| 0.0 | 0.1 | GO:2001045 | negative regulation of integrin-mediated signaling pathway(GO:2001045) |
| 0.0 | 0.4 | GO:0045198 | establishment of epithelial cell apical/basal polarity(GO:0045198) |
| 0.0 | 0.5 | GO:0042373 | vitamin K metabolic process(GO:0042373) |
| 0.0 | 1.3 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.0 | 0.7 | GO:0007220 | Notch receptor processing(GO:0007220) |
| 0.0 | 0.4 | GO:0099515 | vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515) |
| 0.0 | 0.2 | GO:0051835 | positive regulation of synapse structural plasticity(GO:0051835) |
| 0.0 | 0.1 | GO:0001927 | exocyst assembly(GO:0001927) |
| 0.0 | 0.5 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
| 0.0 | 0.3 | GO:0031272 | regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274) |
| 0.0 | 0.2 | GO:0009972 | cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087) |
| 0.0 | 0.4 | GO:0071550 | death-inducing signaling complex assembly(GO:0071550) |
| 0.0 | 0.3 | GO:1902894 | negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894) |
| 0.0 | 0.3 | GO:0032075 | positive regulation of nuclease activity(GO:0032075) |
| 0.0 | 0.4 | GO:1900864 | mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864) |
| 0.0 | 0.3 | GO:0070212 | protein poly-ADP-ribosylation(GO:0070212) |
| 0.0 | 0.3 | GO:0048742 | regulation of skeletal muscle fiber development(GO:0048742) |
| 0.0 | 1.7 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.0 | 0.3 | GO:0036010 | protein localization to endosome(GO:0036010) |
| 0.0 | 0.2 | GO:0042796 | snRNA transcription from RNA polymerase III promoter(GO:0042796) |
| 0.0 | 0.1 | GO:0021526 | somatic motor neuron differentiation(GO:0021523) medial motor column neuron differentiation(GO:0021526) |
| 0.0 | 0.5 | GO:0006782 | protoporphyrinogen IX biosynthetic process(GO:0006782) |
| 0.0 | 0.1 | GO:0045196 | establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) |
| 0.0 | 0.6 | GO:0031110 | regulation of microtubule polymerization or depolymerization(GO:0031110) |
| 0.0 | 0.2 | GO:0014894 | response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
| 0.0 | 0.1 | GO:1901143 | insulin catabolic process(GO:1901143) |
| 0.0 | 0.1 | GO:0051758 | homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758) |
| 0.0 | 0.5 | GO:0035878 | nail development(GO:0035878) |
| 0.0 | 1.1 | GO:0014037 | Schwann cell differentiation(GO:0014037) |
| 0.0 | 0.5 | GO:0048935 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
| 0.0 | 0.1 | GO:0021615 | glossopharyngeal nerve morphogenesis(GO:0021615) |
| 0.0 | 1.3 | GO:0030239 | myofibril assembly(GO:0030239) |
| 0.0 | 0.1 | GO:0021960 | anterior commissure morphogenesis(GO:0021960) |
| 0.0 | 0.3 | GO:0060052 | neurofilament cytoskeleton organization(GO:0060052) |
| 0.0 | 0.1 | GO:0032431 | activation of phospholipase A2 activity(GO:0032431) |
| 0.0 | 0.7 | GO:0071353 | cellular response to interleukin-4(GO:0071353) |
| 0.0 | 0.5 | GO:0032625 | interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619) |
| 0.0 | 0.1 | GO:0000393 | spliceosomal conformational changes to generate catalytic conformation(GO:0000393) |
| 0.0 | 0.1 | GO:0090286 | cytoskeletal anchoring at nuclear membrane(GO:0090286) |
| 0.0 | 2.4 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
| 0.0 | 0.4 | GO:0042340 | keratan sulfate catabolic process(GO:0042340) |
| 0.0 | 0.2 | GO:1904274 | tricellular tight junction assembly(GO:1904274) |
| 0.0 | 0.2 | GO:0043402 | glucocorticoid mediated signaling pathway(GO:0043402) |
| 0.0 | 0.7 | GO:0035825 | reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825) |
| 0.0 | 0.9 | GO:0070534 | protein K63-linked ubiquitination(GO:0070534) |
| 0.0 | 0.1 | GO:0097052 | L-kynurenine metabolic process(GO:0097052) |
| 0.0 | 0.6 | GO:0050435 | beta-amyloid metabolic process(GO:0050435) |
| 0.0 | 0.4 | GO:0060334 | regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334) |
| 0.0 | 0.5 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.0 | 0.3 | GO:0060339 | negative regulation of type I interferon-mediated signaling pathway(GO:0060339) |
| 0.0 | 0.7 | GO:0010165 | response to X-ray(GO:0010165) |
| 0.0 | 0.3 | GO:2001256 | regulation of store-operated calcium entry(GO:2001256) |
| 0.0 | 0.4 | GO:2000828 | regulation of parathyroid hormone secretion(GO:2000828) |
| 0.0 | 0.3 | GO:0006449 | regulation of translational termination(GO:0006449) |
| 0.0 | 0.2 | GO:0010265 | SCF complex assembly(GO:0010265) |
| 0.0 | 0.0 | GO:0019401 | glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401) |
| 0.0 | 0.4 | GO:0007614 | short-term memory(GO:0007614) |
| 0.0 | 0.1 | GO:0072709 | cellular response to sorbitol(GO:0072709) negative regulation of motor neuron apoptotic process(GO:2000672) |
| 0.0 | 0.6 | GO:1901663 | ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663) |
| 0.0 | 0.2 | GO:0045723 | positive regulation of fatty acid biosynthetic process(GO:0045723) |
| 0.0 | 0.4 | GO:0032926 | negative regulation of activin receptor signaling pathway(GO:0032926) |
| 0.0 | 0.1 | GO:2000371 | regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373) |
| 0.0 | 0.2 | GO:0006307 | DNA dealkylation involved in DNA repair(GO:0006307) |
| 0.0 | 0.1 | GO:0046600 | negative regulation of centriole replication(GO:0046600) |
| 0.0 | 0.1 | GO:0030505 | inorganic diphosphate transport(GO:0030505) |
| 0.0 | 0.2 | GO:0009249 | protein lipoylation(GO:0009249) |
| 0.0 | 0.2 | GO:0019388 | galactose catabolic process(GO:0019388) |
| 0.0 | 0.1 | GO:0098838 | reduced folate transmembrane transport(GO:0098838) |
| 0.0 | 0.1 | GO:1902018 | negative regulation of cilium assembly(GO:1902018) |
| 0.0 | 0.9 | GO:2001240 | negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240) |
| 0.0 | 0.2 | GO:0090204 | protein localization to nuclear pore(GO:0090204) |
| 0.0 | 0.3 | GO:0031915 | positive regulation of synaptic plasticity(GO:0031915) |
| 0.0 | 1.3 | GO:0010830 | regulation of myotube differentiation(GO:0010830) |
| 0.0 | 0.1 | GO:0038030 | non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031) |
| 0.0 | 0.2 | GO:0046959 | habituation(GO:0046959) |
| 0.0 | 0.3 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 0.0 | 0.1 | GO:0030916 | otic vesicle formation(GO:0030916) |
| 0.0 | 0.7 | GO:0032481 | positive regulation of type I interferon production(GO:0032481) |
| 0.0 | 0.2 | GO:0034472 | snRNA 3'-end processing(GO:0034472) |
| 0.0 | 0.4 | GO:0006471 | protein ADP-ribosylation(GO:0006471) |
| 0.0 | 0.2 | GO:0097106 | postsynaptic density organization(GO:0097106) |
| 0.0 | 0.5 | GO:0006750 | glutathione biosynthetic process(GO:0006750) |
| 0.0 | 0.7 | GO:0043304 | regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304) |
| 0.0 | 0.3 | GO:0006303 | double-strand break repair via nonhomologous end joining(GO:0006303) |
| 0.0 | 0.3 | GO:0055026 | negative regulation of cardiac muscle tissue development(GO:0055026) |
| 0.0 | 1.0 | GO:0035914 | skeletal muscle cell differentiation(GO:0035914) |
| 0.0 | 0.1 | GO:0035694 | mitochondrial protein catabolic process(GO:0035694) |
| 0.0 | 0.1 | GO:0070561 | vitamin D receptor signaling pathway(GO:0070561) |
| 0.0 | 0.1 | GO:0014807 | regulation of somitogenesis(GO:0014807) |
| 0.0 | 0.2 | GO:0051457 | maintenance of protein location in nucleus(GO:0051457) |
| 0.0 | 3.1 | GO:0035023 | regulation of Rho protein signal transduction(GO:0035023) |
| 0.0 | 0.1 | GO:0010792 | DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) |
| 0.0 | 0.0 | GO:0006540 | glutamate decarboxylation to succinate(GO:0006540) |
| 0.0 | 0.2 | GO:0032836 | glomerular basement membrane development(GO:0032836) |
| 0.0 | 0.4 | GO:0071354 | cellular response to interleukin-6(GO:0071354) |
| 0.0 | 1.1 | GO:0045071 | negative regulation of viral genome replication(GO:0045071) |
| 0.0 | 0.6 | GO:0032570 | response to progesterone(GO:0032570) |
| 0.0 | 0.8 | GO:0032781 | positive regulation of ATPase activity(GO:0032781) |
| 0.0 | 0.5 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.0 | 0.1 | GO:0031293 | membrane protein intracellular domain proteolysis(GO:0031293) |
| 0.0 | 0.2 | GO:0045648 | positive regulation of erythrocyte differentiation(GO:0045648) |
| 0.0 | 1.0 | GO:2000177 | regulation of neural precursor cell proliferation(GO:2000177) |
| 0.0 | 0.1 | GO:0043517 | positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) |
| 0.0 | 0.3 | GO:0035902 | response to immobilization stress(GO:0035902) |
| 0.0 | 0.4 | GO:0042304 | regulation of fatty acid biosynthetic process(GO:0042304) |
| 0.0 | 0.0 | GO:0014034 | neural crest cell fate commitment(GO:0014034) |
| 0.0 | 0.4 | GO:0038202 | TORC1 signaling(GO:0038202) |
| 0.0 | 0.4 | GO:0051923 | sulfation(GO:0051923) |
| 0.0 | 0.1 | GO:0048739 | cardiac muscle fiber development(GO:0048739) |
| 0.0 | 0.1 | GO:0048712 | negative regulation of astrocyte differentiation(GO:0048712) |
| 0.0 | 0.2 | GO:0042769 | DNA damage response, detection of DNA damage(GO:0042769) |
| 0.0 | 0.1 | GO:0045176 | apical protein localization(GO:0045176) |
| 0.0 | 0.8 | GO:0009214 | cyclic nucleotide catabolic process(GO:0009214) |
| 0.0 | 0.0 | GO:0035523 | protein K29-linked deubiquitination(GO:0035523) |
| 0.0 | 0.1 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
| 0.0 | 0.1 | GO:0006265 | DNA topological change(GO:0006265) |
| 0.0 | 0.1 | GO:0045226 | extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379) |
| 0.0 | 0.6 | GO:0048247 | lymphocyte chemotaxis(GO:0048247) |
| 0.0 | 0.2 | GO:0007191 | adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191) |
| 0.0 | 0.3 | GO:2000758 | positive regulation of histone acetylation(GO:0035066) positive regulation of peptidyl-lysine acetylation(GO:2000758) |
| 0.0 | 0.0 | GO:0035582 | sequestering of BMP in extracellular matrix(GO:0035582) sequestering of BMP from receptor via BMP binding(GO:0038098) |
| 0.0 | 0.5 | GO:0032456 | endocytic recycling(GO:0032456) |
| 0.0 | 0.3 | GO:0032007 | negative regulation of TOR signaling(GO:0032007) |
| 0.0 | 0.2 | GO:0051560 | mitochondrial calcium ion homeostasis(GO:0051560) |
| 0.0 | 0.1 | GO:0060412 | ventricular septum morphogenesis(GO:0060412) |
| 0.0 | 0.1 | GO:0006420 | arginyl-tRNA aminoacylation(GO:0006420) |
| 0.0 | 0.6 | GO:0048709 | oligodendrocyte differentiation(GO:0048709) |
| 0.0 | 0.3 | GO:0007274 | neuromuscular synaptic transmission(GO:0007274) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.2 | 31.0 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
| 5.0 | 15.0 | GO:0097135 | cyclin E2-CDK2 complex(GO:0097135) |
| 3.3 | 16.3 | GO:0031436 | BRCA1-BARD1 complex(GO:0031436) |
| 3.2 | 26.0 | GO:0000796 | condensin complex(GO:0000796) |
| 3.2 | 51.2 | GO:0042555 | MCM complex(GO:0042555) |
| 2.6 | 7.8 | GO:0036387 | nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387) |
| 2.6 | 15.5 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 2.0 | 10.2 | GO:0031523 | Myb complex(GO:0031523) |
| 1.9 | 7.6 | GO:0031261 | GINS complex(GO:0000811) DNA replication preinitiation complex(GO:0031261) |
| 1.7 | 13.9 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
| 1.7 | 6.9 | GO:0097125 | cyclin B1-CDK1 complex(GO:0097125) |
| 1.7 | 18.7 | GO:0005638 | lamin filament(GO:0005638) |
| 1.6 | 8.1 | GO:0032449 | CBM complex(GO:0032449) |
| 1.5 | 28.9 | GO:0045120 | pronucleus(GO:0045120) |
| 1.5 | 7.5 | GO:0032301 | MutSalpha complex(GO:0032301) |
| 1.3 | 13.0 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 1.2 | 6.9 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 1.0 | 3.0 | GO:0000939 | condensed chromosome inner kinetochore(GO:0000939) |
| 0.8 | 9.0 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.8 | 3.3 | GO:0002189 | ribose phosphate diphosphokinase complex(GO:0002189) |
| 0.8 | 3.9 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
| 0.7 | 2.2 | GO:0070939 | Dsl1p complex(GO:0070939) |
| 0.7 | 2.2 | GO:0033593 | BRCA2-MAGE-D1 complex(GO:0033593) |
| 0.7 | 31.1 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
| 0.7 | 2.1 | GO:1902737 | dendritic filopodium(GO:1902737) |
| 0.6 | 3.6 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
| 0.6 | 1.7 | GO:1990075 | periciliary membrane compartment(GO:1990075) |
| 0.5 | 2.1 | GO:0033186 | CAF-1 complex(GO:0033186) |
| 0.5 | 4.6 | GO:0036449 | microtubule minus-end(GO:0036449) |
| 0.5 | 1.9 | GO:0008275 | gamma-tubulin small complex(GO:0008275) |
| 0.5 | 39.3 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.4 | 7.1 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
| 0.4 | 4.2 | GO:0070652 | HAUS complex(GO:0070652) |
| 0.4 | 3.1 | GO:0005683 | U7 snRNP(GO:0005683) |
| 0.4 | 2.3 | GO:0031262 | Ndc80 complex(GO:0031262) |
| 0.4 | 2.6 | GO:0098536 | deuterosome(GO:0098536) |
| 0.4 | 1.5 | GO:0031390 | Ctf18 RFC-like complex(GO:0031390) |
| 0.3 | 6.6 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.3 | 22.4 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.3 | 2.5 | GO:0000808 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
| 0.3 | 0.9 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
| 0.3 | 0.6 | GO:0031510 | SUMO activating enzyme complex(GO:0031510) |
| 0.3 | 2.3 | GO:0035976 | AP1 complex(GO:0035976) |
| 0.3 | 2.3 | GO:0071141 | SMAD protein complex(GO:0071141) |
| 0.3 | 1.4 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.3 | 0.5 | GO:0044614 | nuclear pore cytoplasmic filaments(GO:0044614) |
| 0.3 | 0.5 | GO:0005958 | DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) |
| 0.3 | 0.5 | GO:0000805 | X chromosome(GO:0000805) |
| 0.3 | 1.3 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.3 | 0.8 | GO:1990298 | mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298) |
| 0.2 | 0.7 | GO:0097123 | cyclin A1-CDK2 complex(GO:0097123) |
| 0.2 | 0.9 | GO:0033011 | perinuclear theca(GO:0033011) |
| 0.2 | 3.9 | GO:0008091 | spectrin(GO:0008091) |
| 0.2 | 1.5 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 0.2 | 0.6 | GO:0070931 | Golgi-associated vesicle lumen(GO:0070931) |
| 0.2 | 3.2 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.2 | 1.5 | GO:0071797 | LUBAC complex(GO:0071797) |
| 0.2 | 1.2 | GO:0008622 | epsilon DNA polymerase complex(GO:0008622) |
| 0.2 | 2.2 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 0.2 | 3.6 | GO:0097539 | ciliary transition fiber(GO:0097539) |
| 0.2 | 3.2 | GO:0044815 | nucleosome(GO:0000786) DNA packaging complex(GO:0044815) |
| 0.2 | 1.2 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 0.2 | 5.7 | GO:0090545 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.2 | 2.1 | GO:0044327 | dendritic spine head(GO:0044327) |
| 0.2 | 1.1 | GO:1990682 | CSF1-CSF1R complex(GO:1990682) |
| 0.2 | 0.2 | GO:0042565 | RNA nuclear export complex(GO:0042565) |
| 0.2 | 19.1 | GO:0000777 | condensed chromosome kinetochore(GO:0000777) |
| 0.2 | 3.6 | GO:0033276 | transcription factor TFTC complex(GO:0033276) |
| 0.2 | 0.5 | GO:0071148 | TEAD-1-YAP complex(GO:0071148) |
| 0.2 | 0.5 | GO:0035189 | Rb-E2F complex(GO:0035189) |
| 0.2 | 1.0 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.2 | 2.1 | GO:0032059 | bleb(GO:0032059) |
| 0.2 | 21.5 | GO:0000793 | condensed chromosome(GO:0000793) |
| 0.2 | 1.5 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
| 0.2 | 1.4 | GO:0070187 | telosome(GO:0070187) |
| 0.2 | 0.5 | GO:0097058 | CRLF-CLCF1 complex(GO:0097058) |
| 0.1 | 1.6 | GO:0042587 | glycogen granule(GO:0042587) |
| 0.1 | 1.8 | GO:0035253 | ciliary rootlet(GO:0035253) |
| 0.1 | 0.4 | GO:0044609 | DBIRD complex(GO:0044609) |
| 0.1 | 0.4 | GO:0030689 | Noc complex(GO:0030689) |
| 0.1 | 2.9 | GO:0044613 | nuclear pore central transport channel(GO:0044613) |
| 0.1 | 1.9 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.1 | 2.0 | GO:0000242 | pericentriolar material(GO:0000242) |
| 0.1 | 0.4 | GO:0034455 | t-UTP complex(GO:0034455) |
| 0.1 | 1.1 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
| 0.1 | 0.4 | GO:0034677 | integrin alpha7-beta1 complex(GO:0034677) |
| 0.1 | 3.9 | GO:0005865 | striated muscle thin filament(GO:0005865) |
| 0.1 | 2.5 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.1 | 1.5 | GO:0005688 | U6 snRNP(GO:0005688) |
| 0.1 | 1.3 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
| 0.1 | 0.5 | GO:0070435 | Shc-EGFR complex(GO:0070435) |
| 0.1 | 2.5 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.1 | 0.8 | GO:0032021 | NELF complex(GO:0032021) |
| 0.1 | 0.8 | GO:0090661 | box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661) |
| 0.1 | 1.2 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 0.1 | 2.8 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.1 | 0.5 | GO:0072558 | NLRP1 inflammasome complex(GO:0072558) |
| 0.1 | 0.6 | GO:1990246 | uniplex complex(GO:1990246) |
| 0.1 | 0.4 | GO:0000923 | equatorial microtubule organizing center(GO:0000923) |
| 0.1 | 0.9 | GO:0071546 | pi-body(GO:0071546) |
| 0.1 | 0.5 | GO:0035339 | SPOTS complex(GO:0035339) |
| 0.1 | 0.4 | GO:1990851 | Wnt-Frizzled-LRP5/6 complex(GO:1990851) |
| 0.1 | 1.4 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.1 | 0.4 | GO:0035517 | PR-DUB complex(GO:0035517) |
| 0.1 | 1.3 | GO:0005583 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.1 | 1.1 | GO:0031931 | TORC1 complex(GO:0031931) |
| 0.1 | 2.9 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.1 | 1.6 | GO:0005686 | U2 snRNP(GO:0005686) |
| 0.1 | 1.1 | GO:0035068 | micro-ribonucleoprotein complex(GO:0035068) |
| 0.1 | 0.5 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.1 | 0.8 | GO:0036128 | CatSper complex(GO:0036128) |
| 0.1 | 0.5 | GO:0005967 | mitochondrial pyruvate dehydrogenase complex(GO:0005967) |
| 0.1 | 1.0 | GO:0016600 | flotillin complex(GO:0016600) |
| 0.1 | 0.2 | GO:0035370 | UBC13-UEV1A complex(GO:0035370) |
| 0.1 | 0.3 | GO:0005846 | nuclear cap binding complex(GO:0005846) |
| 0.1 | 1.9 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.1 | 1.1 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
| 0.1 | 0.2 | GO:0070685 | macropinocytic cup(GO:0070685) |
| 0.1 | 0.9 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.1 | 1.7 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.1 | 0.2 | GO:0001534 | radial spoke(GO:0001534) |
| 0.1 | 0.3 | GO:0060201 | clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201) |
| 0.1 | 0.5 | GO:0032280 | symmetric synapse(GO:0032280) |
| 0.1 | 3.6 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.1 | 0.3 | GO:0071008 | U2-type post-mRNA release spliceosomal complex(GO:0071008) |
| 0.1 | 0.4 | GO:0070761 | pre-snoRNP complex(GO:0070761) |
| 0.1 | 1.1 | GO:0000812 | Swr1 complex(GO:0000812) |
| 0.1 | 0.8 | GO:0035102 | PRC1 complex(GO:0035102) |
| 0.1 | 0.9 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.1 | 0.3 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
| 0.1 | 0.2 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 0.1 | 0.8 | GO:0005883 | neurofilament(GO:0005883) |
| 0.1 | 0.5 | GO:0045180 | basal cortex(GO:0045180) |
| 0.1 | 1.6 | GO:0030686 | 90S preribosome(GO:0030686) |
| 0.1 | 0.7 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 0.0 | 0.2 | GO:0071458 | integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) |
| 0.0 | 0.3 | GO:0016589 | NURF complex(GO:0016589) |
| 0.0 | 11.4 | GO:0000790 | nuclear chromatin(GO:0000790) |
| 0.0 | 0.3 | GO:0030314 | junctional membrane complex(GO:0030314) |
| 0.0 | 1.3 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.0 | 3.7 | GO:0008287 | protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293) |
| 0.0 | 4.0 | GO:0005814 | centriole(GO:0005814) |
| 0.0 | 0.3 | GO:0030990 | intraciliary transport particle(GO:0030990) |
| 0.0 | 1.9 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.0 | 0.2 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
| 0.0 | 0.8 | GO:0046930 | pore complex(GO:0046930) |
| 0.0 | 4.7 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.0 | 3.3 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.0 | 0.2 | GO:0035363 | histone locus body(GO:0035363) |
| 0.0 | 0.3 | GO:0071986 | Ragulator complex(GO:0071986) |
| 0.0 | 0.6 | GO:0032433 | filopodium tip(GO:0032433) |
| 0.0 | 1.6 | GO:0000775 | chromosome, centromeric region(GO:0000775) |
| 0.0 | 0.5 | GO:0098799 | outer mitochondrial membrane protein complex(GO:0098799) |
| 0.0 | 0.3 | GO:0070554 | synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554) |
| 0.0 | 0.2 | GO:0030934 | anchoring collagen complex(GO:0030934) |
| 0.0 | 0.4 | GO:0032797 | SMN complex(GO:0032797) |
| 0.0 | 0.7 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.0 | 0.1 | GO:0098855 | HCN channel complex(GO:0098855) |
| 0.0 | 0.2 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
| 0.0 | 3.5 | GO:0014704 | intercalated disc(GO:0014704) |
| 0.0 | 2.0 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.0 | 1.0 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.0 | 0.2 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
| 0.0 | 0.3 | GO:0071204 | histone pre-mRNA 3'end processing complex(GO:0071204) |
| 0.0 | 0.5 | GO:0043189 | NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562) |
| 0.0 | 3.9 | GO:0000922 | spindle pole(GO:0000922) |
| 0.0 | 0.8 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.0 | 20.4 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.0 | 0.2 | GO:0089701 | U2AF(GO:0089701) |
| 0.0 | 0.6 | GO:0031527 | filopodium membrane(GO:0031527) |
| 0.0 | 14.2 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.0 | 0.8 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.0 | 1.1 | GO:0072686 | mitotic spindle(GO:0072686) |
| 0.0 | 0.3 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
| 0.0 | 0.3 | GO:0000938 | GARP complex(GO:0000938) |
| 0.0 | 3.0 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 3.7 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 0.0 | 1.3 | GO:0031430 | M band(GO:0031430) |
| 0.0 | 0.2 | GO:0005797 | Golgi medial cisterna(GO:0005797) |
| 0.0 | 2.7 | GO:0005819 | spindle(GO:0005819) |
| 0.0 | 0.5 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.0 | 0.5 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.0 | 0.2 | GO:0005587 | collagen type IV trimer(GO:0005587) |
| 0.0 | 0.8 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.0 | 5.3 | GO:0043292 | contractile fiber(GO:0043292) |
| 0.0 | 1.8 | GO:0005901 | caveola(GO:0005901) |
| 0.0 | 0.8 | GO:0005657 | replication fork(GO:0005657) |
| 0.0 | 0.8 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.0 | 0.7 | GO:0030315 | T-tubule(GO:0030315) |
| 0.0 | 0.4 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.0 | 0.1 | GO:0001652 | granular component(GO:0001652) |
| 0.0 | 11.5 | GO:0005635 | nuclear envelope(GO:0005635) |
| 0.0 | 0.3 | GO:0005685 | U1 snRNP(GO:0005685) |
| 0.0 | 0.4 | GO:0098827 | endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827) |
| 0.0 | 0.4 | GO:0031045 | dense core granule(GO:0031045) |
| 0.0 | 0.1 | GO:0033165 | interphotoreceptor matrix(GO:0033165) |
| 0.0 | 0.0 | GO:1902636 | kinociliary basal body(GO:1902636) |
| 0.0 | 0.1 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
| 0.0 | 1.3 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
| 0.0 | 0.1 | GO:0017109 | glutamate-cysteine ligase complex(GO:0017109) |
| 0.0 | 0.6 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.0 | 0.1 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.0 | 0.2 | GO:0032039 | integrator complex(GO:0032039) |
| 0.0 | 0.2 | GO:0061689 | tricellular tight junction(GO:0061689) |
| 0.0 | 0.9 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 2.5 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.0 | 0.4 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.0 | 0.3 | GO:0097440 | apical dendrite(GO:0097440) |
| 0.0 | 0.2 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.0 | 0.4 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.0 | 0.2 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.0 | 2.2 | GO:0031968 | organelle outer membrane(GO:0031968) |
| 0.0 | 0.0 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 0.0 | 0.9 | GO:0005930 | axoneme(GO:0005930) ciliary plasm(GO:0097014) |
| 0.0 | 0.1 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.2 | 31.0 | GO:0004748 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
| 5.9 | 29.5 | GO:0031493 | nucleosomal histone binding(GO:0031493) |
| 3.0 | 12.2 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
| 2.8 | 14.1 | GO:0003896 | DNA primase activity(GO:0003896) |
| 2.7 | 21.7 | GO:0003910 | DNA ligase (ATP) activity(GO:0003910) |
| 2.1 | 27.1 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 1.9 | 7.7 | GO:0044378 | non-sequence-specific DNA binding, bending(GO:0044378) |
| 1.8 | 25.0 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
| 1.7 | 5.1 | GO:0004157 | dihydropyrimidinase activity(GO:0004157) |
| 1.6 | 4.8 | GO:0004639 | phosphoribosylaminoimidazole carboxylase activity(GO:0004638) phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639) |
| 1.6 | 14.1 | GO:0033170 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 1.6 | 10.9 | GO:0004797 | thymidine kinase activity(GO:0004797) |
| 1.5 | 7.5 | GO:0032143 | single thymine insertion binding(GO:0032143) |
| 1.4 | 20.5 | GO:0043138 | 3'-5' DNA helicase activity(GO:0043138) |
| 1.3 | 6.7 | GO:0043515 | kinetochore binding(GO:0043515) |
| 1.0 | 3.1 | GO:0004170 | dUTP diphosphatase activity(GO:0004170) |
| 1.0 | 47.8 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.9 | 10.3 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.8 | 2.5 | GO:0004418 | hydroxymethylbilane synthase activity(GO:0004418) |
| 0.8 | 2.5 | GO:0080023 | 3R-hydroxyacyl-CoA dehydratase activity(GO:0080023) |
| 0.6 | 0.6 | GO:0004137 | deoxycytidine kinase activity(GO:0004137) |
| 0.6 | 17.3 | GO:0043274 | phospholipase binding(GO:0043274) |
| 0.6 | 3.6 | GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity(GO:0051575) |
| 0.6 | 4.7 | GO:0036310 | annealing helicase activity(GO:0036310) |
| 0.6 | 9.3 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
| 0.6 | 8.0 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.6 | 5.1 | GO:0060002 | plus-end directed microfilament motor activity(GO:0060002) |
| 0.5 | 3.3 | GO:0004749 | ribose phosphate diphosphokinase activity(GO:0004749) |
| 0.5 | 1.5 | GO:0004314 | [acyl-carrier-protein] S-malonyltransferase activity(GO:0004314) S-malonyltransferase activity(GO:0016419) malonyltransferase activity(GO:0016420) |
| 0.5 | 1.4 | GO:0030337 | DNA polymerase processivity factor activity(GO:0030337) |
| 0.5 | 1.4 | GO:0004850 | uridine phosphorylase activity(GO:0004850) |
| 0.5 | 8.2 | GO:0035173 | histone kinase activity(GO:0035173) |
| 0.5 | 5.0 | GO:0042731 | PH domain binding(GO:0042731) |
| 0.4 | 2.2 | GO:0032810 | sterol response element binding(GO:0032810) |
| 0.4 | 3.4 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.4 | 1.7 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
| 0.4 | 2.1 | GO:0033906 | hyaluronoglucuronidase activity(GO:0033906) |
| 0.4 | 1.3 | GO:0008940 | nitrate reductase activity(GO:0008940) molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599) |
| 0.4 | 1.6 | GO:0015111 | iodide transmembrane transporter activity(GO:0015111) |
| 0.4 | 1.2 | GO:0004772 | sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736) |
| 0.4 | 1.6 | GO:0004329 | formate-tetrahydrofolate ligase activity(GO:0004329) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) |
| 0.4 | 1.4 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
| 0.3 | 1.4 | GO:0004088 | carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088) |
| 0.3 | 1.3 | GO:0003953 | NAD+ nucleosidase activity(GO:0003953) |
| 0.3 | 2.0 | GO:0047696 | beta-adrenergic receptor kinase activity(GO:0047696) |
| 0.3 | 1.6 | GO:0004999 | vasoactive intestinal polypeptide receptor activity(GO:0004999) |
| 0.3 | 0.3 | GO:0038181 | bile acid receptor activity(GO:0038181) |
| 0.3 | 2.2 | GO:0010484 | H3 histone acetyltransferase activity(GO:0010484) |
| 0.3 | 1.2 | GO:0051733 | ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) |
| 0.3 | 1.5 | GO:0004370 | glycerol kinase activity(GO:0004370) |
| 0.3 | 2.3 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
| 0.3 | 2.0 | GO:0036137 | kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137) |
| 0.3 | 1.1 | GO:0002054 | nucleobase binding(GO:0002054) purine nucleobase binding(GO:0002060) |
| 0.3 | 8.4 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.3 | 10.5 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.3 | 1.9 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
| 0.3 | 1.6 | GO:0019237 | centromeric DNA binding(GO:0019237) |
| 0.3 | 2.4 | GO:0008970 | phosphatidylcholine 1-acylhydrolase activity(GO:0008970) |
| 0.3 | 2.1 | GO:0030620 | U2 snRNA binding(GO:0030620) |
| 0.3 | 0.8 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
| 0.3 | 1.0 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
| 0.2 | 0.7 | GO:0008401 | retinoic acid 4-hydroxylase activity(GO:0008401) |
| 0.2 | 1.0 | GO:0008192 | RNA guanylyltransferase activity(GO:0008192) |
| 0.2 | 1.6 | GO:0044547 | DNA topoisomerase binding(GO:0044547) |
| 0.2 | 0.9 | GO:0070139 | ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139) |
| 0.2 | 7.0 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 0.2 | 18.8 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.2 | 0.9 | GO:0005006 | epidermal growth factor-activated receptor activity(GO:0005006) |
| 0.2 | 6.0 | GO:0008483 | transaminase activity(GO:0008483) |
| 0.2 | 0.8 | GO:0098808 | mRNA cap binding(GO:0098808) |
| 0.2 | 0.8 | GO:0003839 | gamma-glutamylcyclotransferase activity(GO:0003839) |
| 0.2 | 4.2 | GO:0034596 | phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596) |
| 0.2 | 8.6 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.2 | 5.8 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 0.2 | 0.8 | GO:0086020 | gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020) |
| 0.2 | 1.2 | GO:0034648 | histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648) |
| 0.2 | 1.6 | GO:0050733 | RS domain binding(GO:0050733) |
| 0.2 | 0.6 | GO:0052798 | beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798) |
| 0.2 | 1.1 | GO:0004359 | glutaminase activity(GO:0004359) |
| 0.2 | 1.3 | GO:0042289 | MHC class II protein binding(GO:0042289) |
| 0.2 | 2.2 | GO:0016015 | morphogen activity(GO:0016015) |
| 0.2 | 0.4 | GO:0071208 | histone pre-mRNA DCP binding(GO:0071208) |
| 0.2 | 0.5 | GO:0032090 | Pyrin domain binding(GO:0032090) |
| 0.2 | 0.7 | GO:0008475 | procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) |
| 0.2 | 0.5 | GO:0033746 | histone demethylase activity (H3-R2 specific)(GO:0033746) histone demethylase activity (H4-R3 specific)(GO:0033749) peptidyl-lysine 5-dioxygenase activity(GO:0070815) |
| 0.2 | 1.0 | GO:0051033 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 0.2 | 14.5 | GO:0003684 | damaged DNA binding(GO:0003684) |
| 0.2 | 0.5 | GO:1904455 | ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455) |
| 0.2 | 1.3 | GO:0051373 | FATZ binding(GO:0051373) |
| 0.2 | 1.1 | GO:0005157 | macrophage colony-stimulating factor receptor binding(GO:0005157) |
| 0.2 | 0.6 | GO:0008798 | beta-aspartyl-peptidase activity(GO:0008798) |
| 0.2 | 0.5 | GO:0004611 | phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613) |
| 0.2 | 0.8 | GO:0016774 | phosphotransferase activity, carboxyl group as acceptor(GO:0016774) |
| 0.2 | 5.1 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 0.2 | 9.5 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.2 | 0.6 | GO:0102344 | 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345) |
| 0.1 | 1.8 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
| 0.1 | 1.0 | GO:0008432 | JUN kinase binding(GO:0008432) |
| 0.1 | 0.6 | GO:0004001 | adenosine kinase activity(GO:0004001) |
| 0.1 | 1.3 | GO:0070740 | tubulin-glutamic acid ligase activity(GO:0070740) |
| 0.1 | 0.4 | GO:0055077 | gap junction hemi-channel activity(GO:0055077) |
| 0.1 | 0.5 | GO:0000822 | inositol hexakisphosphate binding(GO:0000822) |
| 0.1 | 0.3 | GO:0071209 | U7 snRNA binding(GO:0071209) |
| 0.1 | 0.5 | GO:0001156 | TFIIIC-class transcription factor binding(GO:0001156) |
| 0.1 | 0.5 | GO:0061676 | importin-alpha family protein binding(GO:0061676) |
| 0.1 | 1.2 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
| 0.1 | 2.0 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
| 0.1 | 0.4 | GO:1904928 | coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928) |
| 0.1 | 6.3 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
| 0.1 | 2.1 | GO:0004017 | adenylate kinase activity(GO:0004017) |
| 0.1 | 0.4 | GO:0030305 | heparanase activity(GO:0030305) |
| 0.1 | 18.2 | GO:0042393 | histone binding(GO:0042393) |
| 0.1 | 0.8 | GO:1904288 | BAT3 complex binding(GO:1904288) |
| 0.1 | 1.3 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
| 0.1 | 1.0 | GO:0008297 | single-stranded DNA exodeoxyribonuclease activity(GO:0008297) |
| 0.1 | 1.7 | GO:0001730 | 2'-5'-oligoadenylate synthetase activity(GO:0001730) |
| 0.1 | 0.3 | GO:0090422 | thiamine pyrophosphate transporter activity(GO:0090422) |
| 0.1 | 0.3 | GO:0080101 | phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101) |
| 0.1 | 1.8 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.1 | 1.0 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 0.1 | 1.4 | GO:0000400 | four-way junction DNA binding(GO:0000400) |
| 0.1 | 4.0 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.1 | 0.4 | GO:0016262 | protein N-acetylglucosaminyltransferase activity(GO:0016262) |
| 0.1 | 2.9 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
| 0.1 | 0.8 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
| 0.1 | 0.4 | GO:0001094 | TFIID-class transcription factor binding(GO:0001094) |
| 0.1 | 0.9 | GO:0042799 | histone methyltransferase activity (H4-K20 specific)(GO:0042799) |
| 0.1 | 0.8 | GO:0009008 | DNA-methyltransferase activity(GO:0009008) |
| 0.1 | 13.4 | GO:0004386 | helicase activity(GO:0004386) |
| 0.1 | 30.7 | GO:0008017 | microtubule binding(GO:0008017) |
| 0.1 | 1.4 | GO:0048156 | tau protein binding(GO:0048156) |
| 0.1 | 0.5 | GO:0003680 | AT DNA binding(GO:0003680) |
| 0.1 | 0.4 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
| 0.1 | 1.5 | GO:0048019 | receptor antagonist activity(GO:0048019) |
| 0.1 | 0.9 | GO:0070087 | chromo shadow domain binding(GO:0070087) |
| 0.1 | 0.8 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.1 | 1.1 | GO:0004723 | calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) |
| 0.1 | 2.8 | GO:0042288 | MHC class I protein binding(GO:0042288) |
| 0.1 | 0.3 | GO:0004677 | DNA-dependent protein kinase activity(GO:0004677) |
| 0.1 | 2.3 | GO:0046965 | retinoid X receptor binding(GO:0046965) |
| 0.1 | 0.4 | GO:0004392 | heme oxygenase (decyclizing) activity(GO:0004392) |
| 0.1 | 1.9 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
| 0.1 | 0.2 | GO:0004938 | alpha2-adrenergic receptor activity(GO:0004938) |
| 0.1 | 0.4 | GO:0035614 | snRNA stem-loop binding(GO:0035614) |
| 0.1 | 1.2 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
| 0.1 | 0.5 | GO:0045174 | glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610) |
| 0.1 | 0.8 | GO:0015288 | porin activity(GO:0015288) |
| 0.1 | 0.3 | GO:0019797 | procollagen-proline 3-dioxygenase activity(GO:0019797) |
| 0.1 | 0.5 | GO:0001515 | opioid peptide activity(GO:0001515) |
| 0.1 | 2.1 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.1 | 0.5 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
| 0.1 | 2.2 | GO:0016876 | aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876) |
| 0.1 | 0.6 | GO:0044388 | small protein activating enzyme binding(GO:0044388) |
| 0.1 | 0.7 | GO:0005237 | inhibitory extracellular ligand-gated ion channel activity(GO:0005237) |
| 0.1 | 0.2 | GO:0016534 | cyclin-dependent protein kinase 5 activator activity(GO:0016534) |
| 0.1 | 0.9 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 0.1 | 4.1 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.1 | 0.4 | GO:0031752 | D5 dopamine receptor binding(GO:0031752) |
| 0.1 | 0.3 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
| 0.1 | 0.3 | GO:0070991 | medium-chain-acyl-CoA dehydrogenase activity(GO:0070991) |
| 0.1 | 1.0 | GO:0048406 | nerve growth factor binding(GO:0048406) |
| 0.1 | 0.5 | GO:0008821 | crossover junction endodeoxyribonuclease activity(GO:0008821) |
| 0.1 | 0.3 | GO:0005499 | vitamin D binding(GO:0005499) |
| 0.1 | 17.6 | GO:0001047 | core promoter binding(GO:0001047) |
| 0.1 | 1.3 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.1 | 0.5 | GO:0047057 | oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057) |
| 0.1 | 0.5 | GO:0005127 | ciliary neurotrophic factor receptor binding(GO:0005127) |
| 0.1 | 0.3 | GO:0046964 | 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964) |
| 0.1 | 0.4 | GO:0042978 | ornithine decarboxylase activator activity(GO:0042978) |
| 0.1 | 0.2 | GO:0016979 | lipoate-protein ligase activity(GO:0016979) |
| 0.1 | 0.7 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
| 0.1 | 3.0 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.1 | 9.2 | GO:0017048 | Rho GTPase binding(GO:0017048) |
| 0.1 | 1.0 | GO:0004065 | arylsulfatase activity(GO:0004065) |
| 0.1 | 2.6 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
| 0.1 | 0.7 | GO:0070411 | I-SMAD binding(GO:0070411) |
| 0.1 | 0.2 | GO:0035033 | histone deacetylase regulator activity(GO:0035033) |
| 0.1 | 0.8 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.1 | 0.2 | GO:0055100 | adiponectin binding(GO:0055100) |
| 0.1 | 0.6 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
| 0.1 | 1.8 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.1 | 0.4 | GO:0050145 | nucleoside phosphate kinase activity(GO:0050145) |
| 0.1 | 2.0 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.1 | 1.0 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 0.1 | 0.5 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
| 0.1 | 0.2 | GO:0035514 | DNA demethylase activity(GO:0035514) |
| 0.1 | 1.7 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
| 0.1 | 0.4 | GO:0086083 | cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083) |
| 0.1 | 0.2 | GO:0008427 | calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858) |
| 0.0 | 0.4 | GO:0098639 | collagen binding involved in cell-matrix adhesion(GO:0098639) |
| 0.0 | 0.3 | GO:0032027 | myosin light chain binding(GO:0032027) |
| 0.0 | 0.6 | GO:0008020 | G-protein coupled photoreceptor activity(GO:0008020) |
| 0.0 | 0.6 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.0 | 0.2 | GO:0047391 | alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391) |
| 0.0 | 0.4 | GO:0050815 | phosphoserine binding(GO:0050815) |
| 0.0 | 2.6 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.0 | 0.2 | GO:0015319 | sodium:inorganic phosphate symporter activity(GO:0015319) |
| 0.0 | 0.3 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
| 0.0 | 4.2 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
| 0.0 | 0.5 | GO:0016634 | oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634) |
| 0.0 | 0.2 | GO:0030172 | troponin C binding(GO:0030172) |
| 0.0 | 0.2 | GO:0044729 | hemi-methylated DNA-binding(GO:0044729) |
| 0.0 | 0.5 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
| 0.0 | 2.7 | GO:0016763 | transferase activity, transferring pentosyl groups(GO:0016763) |
| 0.0 | 2.5 | GO:0004402 | histone acetyltransferase activity(GO:0004402) |
| 0.0 | 0.7 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.0 | 0.6 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.0 | 0.2 | GO:0003963 | RNA-3'-phosphate cyclase activity(GO:0003963) |
| 0.0 | 0.8 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.0 | 4.3 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 0.7 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 0.0 | 1.1 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.0 | 0.2 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
| 0.0 | 0.7 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.0 | 0.5 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.0 | 2.2 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.0 | 3.0 | GO:0004714 | transmembrane receptor protein tyrosine kinase activity(GO:0004714) |
| 0.0 | 1.0 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.0 | 0.6 | GO:0031491 | nucleosome binding(GO:0031491) |
| 0.0 | 0.2 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
| 0.0 | 0.6 | GO:0016423 | tRNA (guanine) methyltransferase activity(GO:0016423) |
| 0.0 | 1.0 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
| 0.0 | 0.4 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 0.0 | 0.2 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
| 0.0 | 0.2 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
| 0.0 | 0.2 | GO:0003917 | DNA topoisomerase type I activity(GO:0003917) |
| 0.0 | 0.1 | GO:0004335 | galactokinase activity(GO:0004335) |
| 0.0 | 0.2 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.0 | 0.8 | GO:0001056 | RNA polymerase III activity(GO:0001056) |
| 0.0 | 0.7 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.0 | 0.2 | GO:0016427 | tRNA (cytosine) methyltransferase activity(GO:0016427) |
| 0.0 | 0.1 | GO:0031626 | beta-endorphin binding(GO:0031626) |
| 0.0 | 0.2 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
| 0.0 | 0.7 | GO:0016805 | dipeptidase activity(GO:0016805) |
| 0.0 | 0.4 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.0 | 0.2 | GO:0030957 | Tat protein binding(GO:0030957) |
| 0.0 | 0.7 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.0 | 1.4 | GO:0097472 | cyclin-dependent protein kinase activity(GO:0097472) |
| 0.0 | 0.2 | GO:0016868 | intramolecular transferase activity, phosphotransferases(GO:0016868) |
| 0.0 | 0.1 | GO:0017098 | sulfonylurea receptor binding(GO:0017098) |
| 0.0 | 1.4 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650) |
| 0.0 | 0.2 | GO:0051434 | BH3 domain binding(GO:0051434) |
| 0.0 | 2.8 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.0 | 2.7 | GO:0019888 | protein phosphatase regulator activity(GO:0019888) |
| 0.0 | 0.1 | GO:1902444 | riboflavin binding(GO:1902444) |
| 0.0 | 0.8 | GO:0051721 | protein phosphatase 2A binding(GO:0051721) |
| 0.0 | 0.5 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
| 0.0 | 0.5 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.0 | 0.8 | GO:0005328 | neurotransmitter:sodium symporter activity(GO:0005328) |
| 0.0 | 0.0 | GO:0008967 | phosphoglycolate phosphatase activity(GO:0008967) |
| 0.0 | 0.3 | GO:0038132 | neuregulin binding(GO:0038132) |
| 0.0 | 0.4 | GO:0031698 | beta-2 adrenergic receptor binding(GO:0031698) |
| 0.0 | 0.4 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.0 | 1.0 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.0 | 0.2 | GO:0004972 | NMDA glutamate receptor activity(GO:0004972) |
| 0.0 | 0.5 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.0 | 0.1 | GO:0071535 | RING-like zinc finger domain binding(GO:0071535) |
| 0.0 | 0.1 | GO:0042835 | BRE binding(GO:0042835) |
| 0.0 | 0.3 | GO:0015166 | polyol transmembrane transporter activity(GO:0015166) |
| 0.0 | 0.1 | GO:0016971 | flavin-linked sulfhydryl oxidase activity(GO:0016971) |
| 0.0 | 0.1 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
| 0.0 | 0.5 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 0.0 | 0.1 | GO:0008518 | reduced folate carrier activity(GO:0008518) |
| 0.0 | 0.3 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
| 0.0 | 0.3 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
| 0.0 | 1.3 | GO:0004112 | cyclic-nucleotide phosphodiesterase activity(GO:0004112) |
| 0.0 | 1.1 | GO:0030170 | pyridoxal phosphate binding(GO:0030170) |
| 0.0 | 0.1 | GO:0047179 | platelet-activating factor acetyltransferase activity(GO:0047179) |
| 0.0 | 0.1 | GO:0043024 | ribosomal small subunit binding(GO:0043024) |
| 0.0 | 0.6 | GO:0008171 | O-methyltransferase activity(GO:0008171) |
| 0.0 | 0.6 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.0 | 0.4 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.0 | 0.1 | GO:0004357 | glutamate-cysteine ligase activity(GO:0004357) |
| 0.0 | 0.6 | GO:0042605 | peptide antigen binding(GO:0042605) |
| 0.0 | 0.2 | GO:0035251 | UDP-glucosyltransferase activity(GO:0035251) |
| 0.0 | 1.9 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
| 0.0 | 0.2 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.0 | 0.1 | GO:0010385 | double-stranded methylated DNA binding(GO:0010385) |
| 0.0 | 0.6 | GO:0008009 | chemokine activity(GO:0008009) |
| 0.0 | 0.1 | GO:0004528 | phosphodiesterase I activity(GO:0004528) |
| 0.0 | 0.1 | GO:0030628 | pre-mRNA 3'-splice site binding(GO:0030628) |
| 0.0 | 0.7 | GO:0050681 | androgen receptor binding(GO:0050681) |
| 0.0 | 0.3 | GO:0005123 | death receptor binding(GO:0005123) |
| 0.0 | 0.1 | GO:0070097 | delta-catenin binding(GO:0070097) |
| 0.0 | 0.1 | GO:0031208 | POZ domain binding(GO:0031208) |
| 0.0 | 1.9 | GO:0001085 | RNA polymerase II transcription factor binding(GO:0001085) |
| 0.0 | 0.1 | GO:1990829 | C-rich single-stranded DNA binding(GO:1990829) |
| 0.0 | 0.3 | GO:0005521 | lamin binding(GO:0005521) |
| 0.0 | 0.3 | GO:0031005 | filamin binding(GO:0031005) |
| 0.0 | 0.3 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.0 | 0.1 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) |
| 0.0 | 0.4 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.0 | 0.5 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
| 0.0 | 1.3 | GO:0035591 | signaling adaptor activity(GO:0035591) |
| 0.0 | 0.1 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
| 0.0 | 0.1 | GO:0003995 | acyl-CoA dehydrogenase activity(GO:0003995) |
| 0.0 | 0.6 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.0 | 0.1 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.0 | 0.7 | GO:0016278 | lysine N-methyltransferase activity(GO:0016278) |
| 0.0 | 0.4 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.0 | 0.5 | GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) |
| 0.0 | 1.5 | GO:0017124 | SH3 domain binding(GO:0017124) |
| 0.0 | 0.1 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.5 | 21.6 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 1.0 | 131.9 | PID E2F PATHWAY | E2F transcription factor network |
| 0.8 | 40.3 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.6 | 4.0 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.5 | 16.9 | PID ATR PATHWAY | ATR signaling pathway |
| 0.3 | 19.1 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.3 | 6.9 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.2 | 13.7 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.2 | 19.7 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.1 | 7.3 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.1 | 16.3 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.1 | 4.5 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.1 | 4.7 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.1 | 3.8 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.1 | 1.2 | ST JAK STAT PATHWAY | Jak-STAT Pathway |
| 0.1 | 0.6 | SA TRKA RECEPTOR | The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. |
| 0.1 | 1.9 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.1 | 8.8 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.1 | 3.4 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.1 | 4.4 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.1 | 0.4 | PID S1P S1P4 PATHWAY | S1P4 pathway |
| 0.1 | 1.3 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.1 | 3.7 | PID HDAC CLASSI PATHWAY | Signaling events mediated by HDAC Class I |
| 0.1 | 3.5 | PID RHOA PATHWAY | RhoA signaling pathway |
| 0.1 | 1.4 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.0 | 3.1 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.0 | 0.8 | PID EPO PATHWAY | EPO signaling pathway |
| 0.0 | 2.9 | PID ANGIOPOIETIN RECEPTOR PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.0 | 0.5 | PID FAS PATHWAY | FAS (CD95) signaling pathway |
| 0.0 | 0.8 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.0 | 0.0 | PID MYC PATHWAY | C-MYC pathway |
| 0.0 | 1.3 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.0 | 1.7 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.0 | 0.4 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
| 0.0 | 1.1 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.0 | 1.2 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.0 | 1.2 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.0 | 0.3 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.0 | 0.9 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.0 | 0.9 | PID BCR 5PATHWAY | BCR signaling pathway |
| 0.0 | 1.2 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
| 0.0 | 0.8 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
| 0.0 | 0.2 | PID NEPHRIN NEPH1 PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
| 0.0 | 0.9 | PID ERBB2 ERBB3 PATHWAY | ErbB2/ErbB3 signaling events |
| 0.0 | 1.4 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.0 | 1.7 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.0 | 0.5 | PID TRAIL PATHWAY | TRAIL signaling pathway |
| 0.0 | 0.3 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
| 0.0 | 0.5 | PID IL2 1PATHWAY | IL2-mediated signaling events |
| 0.0 | 1.3 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.0 | 1.5 | PID CXCR4 PATHWAY | CXCR4-mediated signaling events |
| 0.0 | 0.3 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
| 0.0 | 2.4 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.0 | 0.9 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 0.3 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.0 | 0.6 | PID AMB2 NEUTROPHILS PATHWAY | amb2 Integrin signaling |
| 0.0 | 0.6 | ST G ALPHA I PATHWAY | G alpha i Pathway |
| 0.0 | 0.5 | ST FAS SIGNALING PATHWAY | Fas Signaling Pathway |
| 0.0 | 0.8 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.0 | 1.0 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.0 | 0.8 | PID AP1 PATHWAY | AP-1 transcription factor network |
| 0.0 | 0.2 | PID TCPTP PATHWAY | Signaling events mediated by TCPTP |
| 0.0 | 0.1 | PID GMCSF PATHWAY | GMCSF-mediated signaling events |
| 0.0 | 0.6 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.8 | 63.9 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 2.4 | 72.8 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 2.1 | 30.0 | REACTOME POL SWITCHING | Genes involved in Polymerase switching |
| 1.9 | 17.1 | REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND | Genes involved in Processive synthesis on the lagging strand |
| 1.4 | 21.0 | REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX | Genes involved in Activation of the pre-replicative complex |
| 1.3 | 30.9 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
| 1.3 | 26.5 | REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
| 1.0 | 13.1 | REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS | Genes involved in Activation of ATR in response to replication stress |
| 0.8 | 18.8 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.5 | 7.9 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 0.5 | 9.6 | REACTOME FANCONI ANEMIA PATHWAY | Genes involved in Fanconi Anemia pathway |
| 0.5 | 17.4 | REACTOME PYRIMIDINE METABOLISM | Genes involved in Pyrimidine metabolism |
| 0.5 | 6.9 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.4 | 1.2 | REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
| 0.3 | 0.5 | REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 | Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1 |
| 0.3 | 5.0 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
| 0.3 | 7.5 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.2 | 3.7 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 0.2 | 11.0 | REACTOME MEIOSIS | Genes involved in Meiosis |
| 0.2 | 6.1 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.2 | 2.8 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.2 | 17.3 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.1 | 3.3 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.1 | 4.2 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.1 | 1.5 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 0.1 | 10.2 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.1 | 2.1 | REACTOME FORMATION OF INCISION COMPLEX IN GG NER | Genes involved in Formation of incision complex in GG-NER |
| 0.1 | 3.6 | REACTOME TIE2 SIGNALING | Genes involved in Tie2 Signaling |
| 0.1 | 3.0 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.1 | 2.1 | REACTOME PROCESSING OF INTRONLESS PRE MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
| 0.1 | 3.2 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.1 | 1.5 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.1 | 2.5 | REACTOME DESTABILIZATION OF MRNA BY KSRP | Genes involved in Destabilization of mRNA by KSRP |
| 0.1 | 1.3 | REACTOME PURINE CATABOLISM | Genes involved in Purine catabolism |
| 0.1 | 4.7 | REACTOME DNA REPAIR | Genes involved in DNA Repair |
| 0.1 | 2.1 | REACTOME MITOCHONDRIAL TRNA AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
| 0.1 | 10.6 | REACTOME LATE PHASE OF HIV LIFE CYCLE | Genes involved in Late Phase of HIV Life Cycle |
| 0.1 | 0.8 | REACTOME TELOMERE MAINTENANCE | Genes involved in Telomere Maintenance |
| 0.1 | 0.7 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING | Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling |
| 0.1 | 0.6 | REACTOME KERATAN SULFATE BIOSYNTHESIS | Genes involved in Keratan sulfate biosynthesis |
| 0.1 | 3.3 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.1 | 0.4 | REACTOME RAF MAP KINASE CASCADE | Genes involved in RAF/MAP kinase cascade |
| 0.1 | 4.2 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.1 | 1.0 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.1 | 1.1 | REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 0.1 | 1.4 | REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
| 0.1 | 1.5 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.1 | 1.0 | REACTOME THE NLRP3 INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 0.1 | 4.5 | REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 | Genes involved in SCF(Skp2)-mediated degradation of p27/p21 |
| 0.1 | 0.6 | REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES | Genes involved in p75NTR recruits signalling complexes |
| 0.1 | 3.8 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.1 | 1.0 | REACTOME THE ACTIVATION OF ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
| 0.1 | 2.1 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.1 | 0.8 | REACTOME ROLE OF DCC IN REGULATING APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.1 | 0.8 | REACTOME RNA POL III CHAIN ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |
| 0.1 | 0.4 | REACTOME ERKS ARE INACTIVATED | Genes involved in ERKs are inactivated |
| 0.1 | 1.0 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.0 | 1.1 | REACTOME FGFR1 LIGAND BINDING AND ACTIVATION | Genes involved in FGFR1 ligand binding and activation |
| 0.0 | 0.5 | REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS | Genes involved in Elevation of cytosolic Ca2+ levels |
| 0.0 | 0.3 | REACTOME BINDING AND ENTRY OF HIV VIRION | Genes involved in Binding and entry of HIV virion |
| 0.0 | 0.6 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.0 | 1.1 | REACTOME METABOLISM OF NUCLEOTIDES | Genes involved in Metabolism of nucleotides |
| 0.0 | 3.7 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.0 | 1.0 | REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
| 0.0 | 0.4 | REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
| 0.0 | 1.2 | REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.0 | 0.5 | REACTOME RNA POL III TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
| 0.0 | 0.3 | REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR | Genes involved in Thromboxane signalling through TP receptor |
| 0.0 | 1.1 | REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 | Genes involved in Regulation of AMPK activity via LKB1 |
| 0.0 | 0.7 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.0 | 9.8 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.0 | 0.5 | REACTOME GROWTH HORMONE RECEPTOR SIGNALING | Genes involved in Growth hormone receptor signaling |
| 0.0 | 0.5 | REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
| 0.0 | 0.5 | REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION | Genes involved in RORA Activates Circadian Expression |
| 0.0 | 1.0 | REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.0 | 1.0 | REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
| 0.0 | 0.3 | REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR | Genes involved in Signaling by constitutively active EGFR |
| 0.0 | 0.3 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.0 | 0.4 | REACTOME KERATAN SULFATE DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.0 | 0.6 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.0 | 1.1 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.0 | 0.3 | REACTOME EGFR DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.0 | 2.7 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.0 | 0.5 | REACTOME MRNA SPLICING MINOR PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
| 0.0 | 0.5 | REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS | Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
| 0.0 | 1.6 | REACTOME GLUCAGON TYPE LIGAND RECEPTORS | Genes involved in Glucagon-type ligand receptors |
| 0.0 | 0.9 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.0 | 2.2 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.0 | 0.0 | REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE | Genes involved in Cell death signalling via NRAGE, NRIF and NADE |
| 0.0 | 0.5 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.0 | 1.2 | REACTOME NUCLEAR SIGNALING BY ERBB4 | Genes involved in Nuclear signaling by ERBB4 |
| 0.0 | 0.7 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.0 | 1.2 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.0 | 0.3 | REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY | Genes involved in Adenylate cyclase activating pathway |
| 0.0 | 0.5 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.0 | 0.2 | REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
| 0.0 | 1.1 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.0 | 0.5 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
| 0.0 | 0.5 | REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 0.0 | 0.5 | REACTOME G ALPHA Z SIGNALLING EVENTS | Genes involved in G alpha (z) signalling events |
| 0.0 | 0.6 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.0 | 0.1 | REACTOME CALNEXIN CALRETICULIN CYCLE | Genes involved in Calnexin/calreticulin cycle |
| 0.0 | 0.4 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.0 | 0.3 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.0 | 0.2 | REACTOME METABOLISM OF NON CODING RNA | Genes involved in Metabolism of non-coding RNA |
| 0.0 | 0.4 | REACTOME GPVI MEDIATED ACTIVATION CASCADE | Genes involved in GPVI-mediated activation cascade |
| 0.0 | 0.3 | REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
| 0.0 | 0.2 | REACTOME CD28 DEPENDENT PI3K AKT SIGNALING | Genes involved in CD28 dependent PI3K/Akt signaling |
| 0.0 | 0.1 | REACTOME INWARDLY RECTIFYING K CHANNELS | Genes involved in Inwardly rectifying K+ channels |
| 0.0 | 0.3 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
| 0.0 | 0.4 | REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS | Genes involved in Regulation of Water Balance by Renal Aquaporins |
| 0.0 | 0.7 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
| 0.0 | 0.4 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.0 | 0.6 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |