Project

Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

Navigation
Downloads

Results for E2F8

Z-value: 1.38

Motif logo

Transcription factors associated with E2F8

Gene Symbol Gene ID Gene Info
ENSG00000129173.13 E2F8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2F8hg38_v1_chr11_-_19241598_19241628,
hg38_v1_chr11_-_19240936_19240968
0.727.9e-06Click!

Activity profile of E2F8 motif

Sorted Z-values of E2F8 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of E2F8

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image
Promoter Score Transcript Gene Gene Info
chr20_+_43667105 5.99 ENST00000217026.5
MYB proto-oncogene like 2
chr19_-_51342130 5.96 ENST00000335624.5
V-set and immunoglobulin domain containing 10 like
chr9_-_120877026 5.88 ENST00000436309.5
PHD finger protein 19
chr22_+_19479826 5.42 ENST00000437685.6
ENST00000263201.7
ENST00000404724.7
cell division cycle 45
chr12_+_8822610 5.33 ENST00000299698.12
alpha-2-macroglobulin like 1
chr2_+_10123171 4.88 ENST00000615152.5
ribonucleotide reductase regulatory subunit M2
chr11_+_125625967 4.87 ENST00000428830.6
ENST00000278916.8
ENST00000544373.5
ENST00000532669.5
ENST00000527013.6
ENST00000526937.5
ENST00000534685.5
checkpoint kinase 1
chr2_+_10122730 4.66 ENST00000304567.10
ribonucleotide reductase regulatory subunit M2
chr22_+_35400115 4.53 ENST00000382011.9
ENST00000216122.9
ENST00000416905.1
minichromosome maintenance complex component 5
chr22_+_37675629 4.41 ENST00000215909.10
galectin 1
chr8_-_23404076 4.39 ENST00000524168.1
ENST00000389131.8
ENST00000523833.2
ENST00000519243.1
lysyl oxidase like 2
chr9_-_120877167 4.24 ENST00000373896.8
ENST00000312189.10
PHD finger protein 19
chr11_+_125626229 4.09 ENST00000532449.6
ENST00000534070.5
checkpoint kinase 1
chr2_-_135876382 3.82 ENST00000264156.3
minichromosome maintenance complex component 6
chr19_+_4909430 3.77 ENST00000620565.4
ENST00000613817.4
ENST00000624301.3
ENST00000650932.1
ubiquitin like with PHD and ring finger domains 1
chr17_-_43545707 3.29 ENST00000545089.5
ETS variant transcription factor 4
chr17_+_41819201 3.20 ENST00000455106.1
FKBP prolyl isomerase 10
chr14_-_55191534 3.11 ENST00000395425.6
ENST00000247191.7
DLG associated protein 5
chr10_-_17617235 3.11 ENST00000466335.1
3-hydroxyacyl-CoA dehydratase 1
chr2_+_102311502 2.81 ENST00000404917.6
ENST00000410040.5
interleukin 1 receptor like 1
interleukin 18 receptor 1
chr7_+_26291850 2.78 ENST00000338523.9
ENST00000446848.6
sorting nexin 10
chr20_+_43667019 2.71 ENST00000396863.8
MYB proto-oncogene like 2
chr17_-_43545891 2.67 ENST00000591713.5
ENST00000538265.5
ETS variant transcription factor 4
chr3_+_127598400 2.65 ENST00000265056.12
minichromosome maintenance complex component 2
chr1_-_16980607 2.63 ENST00000375535.4
microfibril associated protein 2
chr12_-_56752366 2.62 ENST00000672280.1
DNA primase subunit 1
chr11_-_19240936 2.59 ENST00000250024.9
E2F transcription factor 8
chr8_+_27774566 2.58 ENST00000519637.1
establishment of sister chromatid cohesion N-acetyltransferase 2
chr12_-_56752311 2.53 ENST00000338193.11
ENST00000550770.1
DNA primase subunit 1
chr11_-_107858777 2.50 ENST00000525815.6
solute carrier family 35 member F2
chr12_+_106774630 2.47 ENST00000392839.6
ENST00000548914.5
ENST00000355478.6
ENST00000552619.1
ENST00000549643.5
ENST00000392837.9
RIC8 guanine nucleotide exchange factor B
chr17_-_43546323 2.47 ENST00000545954.5
ENST00000319349.10
ETS variant transcription factor 4
chr19_+_39655907 2.44 ENST00000392051.4
galectin 16
chr16_+_11345429 2.41 ENST00000576027.1
ENST00000312499.6
ENST00000648619.1
RecQ mediated genome instability 2
chr17_-_43545636 2.40 ENST00000393664.6
ETS variant transcription factor 4
chr11_+_5383812 2.32 ENST00000642046.1
olfactory receptor family 51 subfamily M member 1
chr9_-_35079923 2.25 ENST00000378643.8
ENST00000448890.1
FA complementation group G
chr11_+_35180279 2.23 ENST00000531873.5
CD44 molecule (Indian blood group)
chr11_+_47215032 2.13 ENST00000622090.4
ENST00000378600.7
ENST00000378603.7
damage specific DNA binding protein 2
chr4_-_173333672 2.09 ENST00000438704.6
high mobility group box 2
chr7_-_56051544 2.03 ENST00000395471.7
phosphoserine phosphatase
chr15_-_64381431 1.96 ENST00000558008.3
ENST00000300035.9
ENST00000559519.5
ENST00000380258.6
PCNA clamp associated factor
chr7_-_56051288 1.87 ENST00000419984.6
ENST00000413218.5
ENST00000275605.8
ENST00000424596.1
ENST00000421312.5
ENST00000416592.1
phosphoserine phosphatase
chr17_-_76585808 1.86 ENST00000225276.10
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
chr11_-_19241598 1.83 ENST00000532666.1
ENST00000527884.5
ENST00000620009.4
E2F transcription factor 8
chr1_+_70411180 1.82 ENST00000411986.6
cystathionine gamma-lyase
chr1_-_150720842 1.82 ENST00000442853.5
ENST00000368995.8
ENST00000322343.11
ENST00000361824.7
HORMA domain containing 1
chr1_+_156054761 1.78 ENST00000368305.9
ENST00000368304.9
ENST00000368302.3
late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
chr7_+_2244476 1.77 ENST00000397049.2
nudix hydrolase 1
chr12_+_122527229 1.74 ENST00000450485.6
ENST00000333479.12
kinetochore associated 1
chr1_+_70411241 1.68 ENST00000370938.8
ENST00000346806.2
cystathionine gamma-lyase
chr12_-_8662619 1.64 ENST00000544889.1
ENST00000543369.5
microfibril associated protein 5
chr17_+_39738317 1.64 ENST00000394211.7
growth factor receptor bound protein 7
chr1_-_25905989 1.61 ENST00000399728.5
stathmin 1
chr3_+_44761765 1.57 ENST00000326047.9
kinesin family member 15
chr22_+_42553862 1.57 ENST00000340239.8
ENST00000327678.10
serine hydrolase like 2
chr19_-_49361475 1.56 ENST00000598810.5
TEA domain transcription factor 2
chr12_-_8662703 1.55 ENST00000535336.5
microfibril associated protein 5
chr21_+_38272410 1.51 ENST00000398934.5
ENST00000398930.5
potassium inwardly rectifying channel subfamily J member 15
chr7_+_135557904 1.50 ENST00000285968.11
nucleoporin 205
chr18_+_24139013 1.48 ENST00000399481.6
ENST00000327201.10
calcium binding tyrosine phosphorylation regulated
chr11_+_47214937 1.46 ENST00000256996.9
damage specific DNA binding protein 2
chr18_+_24139053 1.44 ENST00000463087.5
ENST00000585037.5
ENST00000399496.8
ENST00000486759.6
ENST00000577705.1
ENST00000415309.6
ENST00000621648.4
ENST00000581397.5
calcium binding tyrosine phosphorylation regulated
chr14_+_24429932 1.42 ENST00000556842.5
ENST00000553935.6
KH and NYN domain containing
chr4_-_21697755 1.41 ENST00000382148.7
potassium voltage-gated channel interacting protein 4
chr19_+_4402615 1.40 ENST00000301280.10
chromatin assembly factor 1 subunit A
chr6_+_109978297 1.38 ENST00000275169.5
G protein-coupled receptor 6
chr3_+_197950176 1.37 ENST00000448864.6
ENST00000647248.2
ribosomal protein L35a
chr14_+_64388296 1.37 ENST00000554739.5
ENST00000554768.6
ENST00000652179.1
ENST00000652337.1
ENST00000557370.3
methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1
chr8_+_127736220 1.36 ENST00000524013.2
ENST00000621592.8
MYC proto-oncogene, bHLH transcription factor
chr8_-_91040814 1.36 ENST00000520014.1
ENST00000285419.8
phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2
chr6_+_109978256 1.34 ENST00000414000.3
G protein-coupled receptor 6
chr8_+_47961028 1.34 ENST00000650216.1
minichromosome maintenance complex component 4
chr8_+_27774530 1.34 ENST00000305188.13
establishment of sister chromatid cohesion N-acetyltransferase 2
chr18_+_24138958 1.32 ENST00000627314.1
calcium binding tyrosine phosphorylation regulated
chr17_+_77405070 1.28 ENST00000585930.5
septin 9
chr1_+_32817442 1.25 ENST00000373476.5
ENST00000529027.5
S100P binding protein
chr1_-_52033772 1.24 ENST00000371614.2
KTI12 chromatin associated homolog
chr19_+_50384323 1.23 ENST00000599857.7
ENST00000613923.6
ENST00000601098.6
ENST00000440232.7
ENST00000595904.6
ENST00000593887.1
DNA polymerase delta 1, catalytic subunit
chr12_+_56128217 1.22 ENST00000267113.4
ENST00000394048.10
extended synaptotagmin 1
chr8_+_47960883 1.21 ENST00000648407.1
ENST00000649838.1
ENST00000649919.1
ENST00000262105.6
ENST00000649973.1
minichromosome maintenance complex component 4
chr6_+_69866546 1.21 ENST00000620364.5
collagen type XIX alpha 1 chain
chr22_-_17007992 1.20 ENST00000643316.1
ENST00000400588.5
GRB2 associated binding protein family member 4
chr15_+_75347727 1.17 ENST00000565051.5
ENST00000564257.1
ENST00000567005.1
nei like DNA glycosylase 1
chr8_+_127736046 1.17 ENST00000641036.1
ENST00000377970.6
MYC proto-oncogene, bHLH transcription factor
chr9_-_135699473 1.16 ENST00000425225.2
ENST00000298466.9
spermatogenesis and oogenesis specific basic helix-loop-helix 1
chr19_-_49362376 1.16 ENST00000601519.5
ENST00000593945.6
ENST00000539846.5
ENST00000596757.1
ENST00000311227.6
TEA domain transcription factor 2
chr6_+_26251607 1.15 ENST00000619466.2
H2B clustered histone 9
chr4_-_129093548 1.14 ENST00000503401.1
sodium channel and clathrin linker 1
chr14_-_23365149 1.13 ENST00000216733.8
embryonal Fyn-associated substrate
chr3_+_155083523 1.13 ENST00000680057.1
membrane metalloendopeptidase
chr16_-_370338 1.11 ENST00000450882.1
ENST00000441883.5
ENST00000447696.5
ENST00000389675.6
mitochondrial ribosomal protein L28
chr15_-_88913362 1.11 ENST00000558029.5
ENST00000268150.13
ENST00000542878.5
ENST00000268151.11
ENST00000566497.5
milk fat globule EGF and factor V/VIII domain containing
chr1_+_150272772 1.09 ENST00000369098.3
ENST00000369099.8
chromosome 1 open reading frame 54
chr11_+_126355894 1.09 ENST00000530591.5
ENST00000534083.5
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr11_+_13009306 1.08 ENST00000529419.3
Ras association domain family member 10
chr11_+_126355634 1.06 ENST00000227495.10
ENST00000676545.1
ENST00000678865.1
ENST00000444328.7
ENST00000677503.1
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr4_-_173334249 1.06 ENST00000506267.1
ENST00000296503.10
high mobility group box 2
chr10_+_113553039 1.05 ENST00000351270.4
hyaluronan binding protein 2
chrX_+_136532205 1.05 ENST00000370634.8
vestigial like family member 1
chrX_+_52751132 1.05 ENST00000616191.4
ENST00000596480.6
ENST00000612490.1
SSX family member 2B
chr9_-_120926752 1.05 ENST00000373887.8
TNF receptor associated factor 1
chr11_+_74171266 1.04 ENST00000328257.13
ENST00000398427.6
protein phosphatase methylesterase 1
chr2_-_214809650 1.03 ENST00000260947.9
ENST00000613706.5
BRCA1 associated RING domain 1
chr14_-_24429665 1.03 ENST00000267406.11
cerebellin 3 precursor
chr2_-_130181542 1.02 ENST00000441135.1
ENST00000680679.1
ENST00000680401.1
ENST00000351288.10
ENST00000680298.1
ENST00000431183.6
sphingomyelin phosphodiesterase 4
chr22_+_29603658 1.01 ENST00000334961.11
ENST00000353887.8
neurofibromin 2
chrX_-_52707161 1.00 ENST00000336777.9
ENST00000337502.5
SSX family member 2
chr22_+_20117734 0.99 ENST00000416427.5
ENST00000421656.5
ENST00000423859.5
ENST00000418705.2
RAN binding protein 1
chr19_+_11435619 0.98 ENST00000589126.5
ENST00000588269.1
ENST00000587509.5
ENST00000591462.6
ENST00000592741.5
ENST00000677123.1
ENST00000593101.5
ENST00000587327.5
protein kinase C substrate 80K-H
chr1_+_32817645 0.97 ENST00000526230.1
ENST00000373475.10
ENST00000531256.1
ENST00000482212.1
S100P binding protein
chr15_+_43826961 0.96 ENST00000381246.6
ENST00000452115.1
ENST00000263795.11
WD repeat domain 76
chrX_-_154653579 0.96 ENST00000247306.4
ENST00000369585.4
cancer/testis antigen 2
chr7_+_114922854 0.92 ENST00000423503.1
ENST00000427207.5
MyoD family inhibitor domain containing
chr17_+_58692563 0.92 ENST00000461271.5
ENST00000583539.5
ENST00000337432.9
ENST00000421782.3
RAD51 paralog C
chr11_+_33376077 0.91 ENST00000658780.2
KIAA1549 like
chrX_+_132023294 0.90 ENST00000481105.5
ENST00000354719.10
ENST00000394334.7
ENST00000394335.6
serine/threonine kinase 26
chr9_-_133163895 0.90 ENST00000372036.4
ENST00000372038.7
ENST00000487864.1
ENST00000372040.9
ENST00000540636.6
ENST00000646215.1
ENST00000372043.7
ENST00000470431.5
ENST00000647146.1
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS blood group)
novel protein
chr10_+_110644306 0.89 ENST00000369519.4
RNA binding motif protein 20
chr12_+_20368495 0.88 ENST00000359062.4
phosphodiesterase 3A
chr4_-_129093454 0.88 ENST00000281142.10
ENST00000511426.5
sodium channel and clathrin linker 1
chrX_+_119399286 0.87 ENST00000217909.8
solute carrier family 25 member 43
chr11_-_13463168 0.85 ENST00000526841.1
ENST00000278174.10
ENST00000529708.5
ENST00000528120.5
BTB domain containing 10
chr4_-_99088704 0.84 ENST00000626055.2
ENST00000296412.14
alcohol dehydrogenase 5 (class III), chi polypeptide
chrX_-_23743201 0.83 ENST00000492081.1
ENST00000379303.10
ENST00000336430.11
acyl-CoA thioesterase 9
chr9_-_72060605 0.82 ENST00000377024.8
ENST00000651200.2
ENST00000652752.1
chromosome 9 open reading frame 57
chr1_+_248445512 0.82 ENST00000642130.1
ENST00000641925.2
olfactory receptor family 2 subfamily T member 2
chr14_-_50668287 0.82 ENST00000556735.1
ENST00000324679.5
salvador family WW domain containing protein 1
chr1_-_43172504 0.81 ENST00000431635.6
EBNA1 binding protein 2
chr9_+_128566741 0.79 ENST00000630866.1
spectrin alpha, non-erythrocytic 1
chr16_+_56657999 0.77 ENST00000568475.1
metallothionein 1F
chr22_+_20117497 0.76 ENST00000331821.7
ENST00000411892.5
RAN binding protein 1
chr7_+_114922561 0.75 ENST00000448022.1
MyoD family inhibitor domain containing
chr4_+_152779934 0.75 ENST00000451320.6
ENST00000429148.6
ENST00000353617.7
ENST00000405727.6
ENST00000356064.3
ADP ribosylation factor interacting protein 1
chr22_+_40346461 0.74 ENST00000623632.4
ENST00000625194.4
ENST00000637666.2
ENST00000680978.1
ENST00000623063.3
ENST00000679723.1
ENST00000342312.9
adenylosuccinate lyase
chr2_+_130181662 0.73 ENST00000425361.5
ENST00000457492.5
mitotic spindle organizing protein 2B
chr1_-_159923717 0.73 ENST00000368096.5
transgelin 2
chr7_+_100539188 0.72 ENST00000300176.9
ArfGAP with FG repeats 2
chr9_-_128724088 0.71 ENST00000406904.2
ENST00000452105.5
ENST00000372667.9
ENST00000372663.9
zinc finger DHHC-type palmitoyltransferase 12
chrX_-_40735476 0.71 ENST00000324817.6
mediator complex subunit 14
chrX_+_55000329 0.69 ENST00000374987.4
apurinic/apyrimidinic endodeoxyribonuclease 2
chr14_+_104689588 0.69 ENST00000330634.11
ENST00000392634.9
ENST00000675482.1
ENST00000398337.8
inverted formin 2
chr15_+_81000913 0.67 ENST00000267984.4
talin rod domain containing 1
chr22_+_40346508 0.67 ENST00000636714.1
ENST00000216194.11
ENST00000623978.3
ENST00000636265.1
ENST00000680378.1
adenylosuccinate lyase
chr20_-_2664186 0.67 ENST00000474315.5
ENST00000380843.9
ENST00000380851.9
ENST00000613370.1
isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta
chrX_+_52184874 0.66 ENST00000599522.7
ENST00000471932.6
MAGE family member D4
chr12_+_55931148 0.65 ENST00000549629.5
ENST00000555218.5
ENST00000331886.10
diacylglycerol kinase alpha
chr12_-_70609788 0.65 ENST00000547715.1
ENST00000538708.5
ENST00000550857.5
ENST00000261266.9
protein tyrosine phosphatase receptor type B
chr4_+_25312766 0.64 ENST00000302874.9
ENST00000612982.1
zinc finger CCHC-type containing 4
chr19_-_46788586 0.64 ENST00000542575.6
solute carrier family 1 member 5
chr1_-_111140040 0.63 ENST00000286692.8
ENST00000484310.6
DNA damage regulated autophagy modulator 2
chr10_+_69088096 0.63 ENST00000242465.4
serglycin
chr2_+_131476112 0.63 ENST00000321253.7
tubulin alpha 3d
chr5_+_66828762 0.63 ENST00000490016.6
ENST00000403666.5
ENST00000450827.5
microtubule associated serine/threonine kinase family member 4
chr4_+_15427998 0.62 ENST00000444304.3
C1q and TNF related 7
chr12_-_116881431 0.62 ENST00000257572.5
harakiri, BCL2 interacting protein
chr4_-_8127650 0.61 ENST00000545242.6
ENST00000676532.1
actin binding LIM protein family member 2
chr7_-_100827504 0.61 ENST00000616502.4
ENST00000358173.8
EPH receptor B4
chr16_+_56657924 0.61 ENST00000334350.7
metallothionein 1F
chr4_-_4542034 0.61 ENST00000306200.7
syntaxin 18
chr19_-_45643688 0.60 ENST00000536630.5
EMAP like 2
chr1_+_153357846 0.60 ENST00000368738.4
S100 calcium binding protein A9
chr2_-_208129824 0.60 ENST00000282141.4
crystallin gamma C
chr13_-_19181773 0.60 ENST00000618094.1
ENST00000400113.8
tubulin alpha 3c
chr15_-_34343112 0.60 ENST00000557912.1
ENST00000328848.6
NOP10 ribonucleoprotein
chr10_+_69278492 0.59 ENST00000643399.2
hexokinase 1
chr2_-_164841410 0.58 ENST00000342193.8
ENST00000375458.6
cordon-bleu WH2 repeat protein like 1
chr9_-_23821275 0.58 ENST00000380110.8
ELAV like RNA binding protein 2
chr4_+_54229261 0.58 ENST00000508170.5
ENST00000512143.1
ENST00000257290.10
platelet derived growth factor receptor alpha
chr12_+_56752449 0.58 ENST00000554643.5
ENST00000556650.5
ENST00000554150.5
ENST00000554155.1
hydroxysteroid 17-beta dehydrogenase 6
chr6_+_24356903 0.57 ENST00000274766.2
kidney associated antigen 1
chr20_+_33007695 0.56 ENST00000170150.4
BPI fold containing family B member 2
chr17_-_15262537 0.56 ENST00000395936.7
ENST00000675819.1
ENST00000674707.1
ENST00000675854.1
ENST00000426385.4
ENST00000395938.7
ENST00000612492.5
ENST00000675808.1
peripheral myelin protein 22
chr6_-_41779859 0.56 ENST00000373018.7
fibroblast growth factor receptor substrate 3
chr19_+_2236816 0.56 ENST00000221494.10
splicing factor 3a subunit 2
chr1_-_158686700 0.55 ENST00000643759.2
spectrin alpha, erythrocytic 1
chr4_+_15339818 0.55 ENST00000397700.6
ENST00000295297.4
C1q and TNF related 7
chr6_-_30932147 0.55 ENST00000359086.4
surfactant associated 2
chr3_-_125595488 0.54 ENST00000296220.6
oxysterol binding protein like 11
chr12_+_109900518 0.54 ENST00000312777.9
ENST00000536408.2
trichoplein keratin filament binding
chr11_-_114559866 0.54 ENST00000534921.2
neurexophilin and PC-esterase domain family member 1
chr6_-_2962097 0.53 ENST00000380524.5
serpin family B member 6
chr2_-_24360445 0.53 ENST00000443927.5
ENST00000406921.7
ENST00000412011.5
ENST00000355123.9
intersectin 2
chr12_-_16608183 0.53 ENST00000354662.5
ENST00000538051.5
LIM domain only 3
chr17_-_58007217 0.53 ENST00000258962.5
ENST00000582730.6
ENST00000584773.5
ENST00000585096.1
serine and arginine rich splicing factor 1
chrX_-_52069172 0.52 ENST00000486010.1
ENST00000497164.5
ENST00000360134.10
ENST00000485287.5
ENST00000335504.9
MAGE family member D4B
chr1_-_32362081 0.52 ENST00000432622.1
family with sequence similarity 229 member A
chr16_-_71230676 0.52 ENST00000321489.9
ENST00000539973.5
ENST00000288168.14
ENST00000545267.1
ENST00000541601.5
ENST00000393567.7
ENST00000538248.5
HYDIN axonemal central pair apparatus protein
chr10_+_104269163 0.52 ENST00000338595.7
glutathione S-transferase omega 2
chr8_+_7926337 0.51 ENST00000400120.3
zinc finger protein 705B
chr19_-_54280498 0.49 ENST00000391746.5
leukocyte immunoglobulin like receptor B2
chr22_+_29603556 0.48 ENST00000413209.6
ENST00000403435.5
ENST00000361452.8
ENST00000403999.7
ENST00000338641.10
ENST00000672896.1
neurofibromin 2
chr3_+_69936629 0.48 ENST00000394348.2
ENST00000531774.1
melanocyte inducing transcription factor
chr9_+_111525148 0.48 ENST00000358151.8
ENST00000309235.6
ENST00000355824.7
ENST00000374374.3
zinc finger protein 483
chr2_-_113235443 0.48 ENST00000465084.1
paired box 8
chr3_-_51875597 0.47 ENST00000446461.2
IQ motif containing F5
chr11_+_24496988 0.46 ENST00000336930.11
leucine zipper protein 2
chr17_+_7012417 0.45 ENST00000548577.5
ribonuclease K
chr6_+_26204552 0.45 ENST00000615164.2
H4 clustered histone 5
chr17_+_7012601 0.44 ENST00000570898.1
ENST00000593646.6
ENST00000552039.2
ENST00000552842.1
ENST00000549393.2
ribonuclease K

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 9.0 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
1.8 5.4 GO:0031938 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) regulation of chromatin silencing at telomere(GO:0031938) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
1.5 4.4 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
1.0 10.1 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.9 4.4 GO:0002317 plasma cell differentiation(GO:0002317)
0.8 3.9 GO:0034421 post-translational protein acetylation(GO:0034421)
0.7 5.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.7 3.5 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.7 9.0 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.6 2.5 GO:0090096 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.5 3.1 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.4 3.0 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.4 3.8 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
0.4 2.6 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.3 1.4 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.3 9.5 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.3 1.2 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.3 3.9 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.3 1.4 GO:0006167 AMP biosynthetic process(GO:0006167)
0.3 0.8 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.3 2.7 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.2 3.6 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.2 1.8 GO:0046061 dGTP catabolic process(GO:0006203) dATP metabolic process(GO:0046060) dATP catabolic process(GO:0046061)
0.2 1.9 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.2 0.6 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.2 3.1 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.2 0.6 GO:0072275 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.2 0.5 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.2 2.2 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.2 1.2 GO:0030259 lipid glycosylation(GO:0030259)
0.2 0.7 GO:0061358 negative regulation of Wnt protein secretion(GO:0061358)
0.2 0.6 GO:0010585 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.2 3.1 GO:0030497 fatty acid elongation(GO:0030497)
0.2 0.6 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.2 0.6 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 0.6 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.1 4.2 GO:0003351 epithelial cilium movement(GO:0003351) sperm capacitation(GO:0048240)
0.1 2.4 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.1 1.6 GO:1905098 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 0.9 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1 2.7 GO:0030903 notochord development(GO:0030903)
0.1 0.9 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 1.5 GO:0014010 Schwann cell proliferation(GO:0014010)
0.1 2.7 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.1 1.1 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 1.9 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.5 GO:2000612 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.1 4.3 GO:0046688 response to copper ion(GO:0046688)
0.1 1.1 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 0.4 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.1 0.4 GO:1903294 regulation of glutamate secretion, neurotransmission(GO:1903294) positive regulation of glutamate secretion, neurotransmission(GO:1903296)
0.1 4.0 GO:0097503 sialylation(GO:0097503)
0.1 0.6 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.1 0.3 GO:0001983 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.1 0.7 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 0.7 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
0.1 1.2 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.1 0.4 GO:1904640 response to methionine(GO:1904640)
0.1 3.4 GO:0000732 strand displacement(GO:0000732)
0.1 0.3 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.1 0.3 GO:1904732 regulation of electron carrier activity(GO:1904732)
0.1 0.2 GO:0098758 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.1 0.6 GO:0006710 androgen catabolic process(GO:0006710)
0.1 0.2 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.1 11.4 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.1 1.0 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.6 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 2.1 GO:0034063 stress granule assembly(GO:0034063)
0.1 1.4 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 3.0 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 0.2 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.1 0.2 GO:0031052 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) oncogene-induced cell senescence(GO:0090402) positive regulation of cellular response to X-ray(GO:2000685)
0.1 0.5 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 1.5 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.1 0.7 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 2.4 GO:0006270 DNA replication initiation(GO:0006270)
0.1 1.7 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.1 0.5 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.6 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.6 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.1 0.5 GO:0090487 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
0.1 3.2 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.3 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
0.0 0.4 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 1.0 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.2 GO:0000189 MAPK import into nucleus(GO:0000189)
0.0 1.0 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 1.5 GO:0015695 organic cation transport(GO:0015695)
0.0 0.9 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.3 GO:1903297 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
0.0 0.2 GO:0002554 serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554)
0.0 0.9 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 1.7 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 1.8 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 2.9 GO:0001541 ovarian follicle development(GO:0001541)
0.0 0.8 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.8 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 0.4 GO:0007144 female meiosis I(GO:0007144)
0.0 0.5 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 1.8 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:2000813 negative regulation of barbed-end actin filament capping(GO:2000813)
0.0 0.6 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.3 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.7 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 2.5 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.3 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.9 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.2 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.6 GO:0032060 bleb assembly(GO:0032060)
0.0 0.6 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.1 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.0 0.7 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 1.2 GO:0051693 actin filament capping(GO:0051693)
0.0 0.2 GO:0035791 platelet-derived growth factor receptor-beta signaling pathway(GO:0035791)
0.0 0.4 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.9 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.0 0.7 GO:0018345 protein palmitoylation(GO:0018345)
0.0 6.2 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.7 GO:0006284 base-excision repair(GO:0006284)
0.0 1.0 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 1.4 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 1.6 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.6 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.5 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.0 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0 1.9 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 9.5 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
1.8 5.4 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
1.7 8.7 GO:0031523 Myb complex(GO:0031523)
1.1 4.2 GO:0097229 sperm end piece(GO:0097229)
0.9 5.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.8 13.3 GO:0042555 MCM complex(GO:0042555)
0.7 1.4 GO:0033186 CAF-1 complex(GO:0033186)
0.7 2.7 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.5 1.5 GO:0044611 nuclear pore inner ring(GO:0044611)
0.4 1.7 GO:1990423 RZZ complex(GO:1990423)
0.3 3.6 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.3 1.6 GO:0005873 plus-end kinesin complex(GO:0005873)
0.3 2.8 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.3 8.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.3 3.9 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.2 1.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.2 5.8 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.2 1.8 GO:0071986 Ragulator complex(GO:0071986)
0.2 1.0 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.2 2.2 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.2 0.9 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.2 0.5 GO:1990716 axonemal central apparatus(GO:1990716)
0.2 3.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 3.8 GO:0005720 nuclear heterochromatin(GO:0005720)
0.1 1.9 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 2.0 GO:0071439 clathrin complex(GO:0071439)
0.1 0.7 GO:0070847 core mediator complex(GO:0070847)
0.1 0.6 GO:1990246 uniplex complex(GO:1990246)
0.1 0.7 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 0.4 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 0.6 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.1 0.6 GO:0032437 cuticular plate(GO:0032437)
0.1 0.5 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 0.4 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 6.5 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.1 0.8 GO:0008091 spectrin(GO:0008091)
0.0 0.3 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 1.2 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.5 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.5 GO:0045179 apical cortex(GO:0045179)
0.0 0.3 GO:0005683 U7 snRNP(GO:0005683)
0.0 1.2 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.2 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.3 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.6 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.2 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 11.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.6 GO:0042588 zymogen granule(GO:0042588)
0.0 0.3 GO:0070449 elongin complex(GO:0070449)
0.0 2.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 2.1 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.3 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 3.1 GO:0000793 condensed chromosome(GO:0000793)
0.0 0.6 GO:0043218 compact myelin(GO:0043218)
0.0 1.1 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.7 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 1.7 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 2.4 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 15.6 GO:0005730 nucleolus(GO:0005730)
0.0 0.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 1.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.0 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 1.2 GO:0005604 basement membrane(GO:0005604)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 9.0 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
1.9 9.5 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
1.4 6.8 GO:0030395 lactose binding(GO:0030395)
1.0 5.2 GO:0003896 DNA primase activity(GO:0003896)
1.0 3.1 GO:0080023 3R-hydroxyacyl-CoA dehydratase activity(GO:0080023)
1.0 3.0 GO:0002113 interleukin-33 binding(GO:0002113)
0.8 3.1 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.8 3.9 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.8 3.8 GO:0031493 nucleosomal histone binding(GO:0031493)
0.7 4.4 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.6 10.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.6 1.8 GO:0047693 GTP diphosphatase activity(GO:0036219) 2-hydroxy-adenosine triphosphate pyrophosphatase activity(GO:0044713) 2-hydroxy-(deoxy)adenosine-triphosphate pyrophosphatase activity(GO:0044714) ATP diphosphatase activity(GO:0047693)
0.4 3.5 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.4 2.1 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.3 1.4 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.3 0.9 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.3 0.8 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.2 1.9 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.2 3.5 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.2 0.7 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.2 2.7 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.2 0.7 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.2 0.8 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.2 0.7 GO:0004979 beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.2 1.4 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 0.3 GO:0017129 triglyceride binding(GO:0017129)
0.1 3.2 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 6.0 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 8.9 GO:0035064 methylated histone binding(GO:0035064)
0.1 1.8 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.7 GO:0032396 inhibitory MHC class I receptor activity(GO:0032396)
0.1 0.9 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 2.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.5 GO:0050610 glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.1 0.6 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 1.0 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.2 GO:0019959 interleukin-8 binding(GO:0019959)
0.1 1.2 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.1 0.6 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 2.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 1.7 GO:0030957 Tat protein binding(GO:0030957)
0.1 0.6 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.3 GO:0031716 calcitonin receptor binding(GO:0031716)
0.1 0.3 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.1 2.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.8 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1 1.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 1.4 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.1 1.8 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.5 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.1 0.6 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 1.9 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 0.3 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 0.3 GO:0030620 U2 snRNA binding(GO:0030620)
0.1 1.0 GO:0031996 thioesterase binding(GO:0031996)
0.1 0.5 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.1 0.6 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 4.3 GO:0003684 damaged DNA binding(GO:0003684)
0.0 1.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.8 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 5.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 4.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 3.0 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0090422 thiamine pyrophosphate transporter activity(GO:0090422)
0.0 0.2 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.9 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 1.6 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.3 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.3 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 1.6 GO:0000049 tRNA binding(GO:0000049)
0.0 1.2 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 1.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 1.0 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.9 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 2.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.8 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 2.2 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.6 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 2.6 GO:0032947 protein complex scaffold(GO:0032947)
0.0 1.0 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.6 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 5.4 GO:0001047 core promoter binding(GO:0001047)
0.0 4.4 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.2 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.5 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 1.7 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.1 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.8 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0008641 small protein activating enzyme activity(GO:0008641)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 8.7 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2 22.0 PID E2F PATHWAY E2F transcription factor network
0.1 11.0 PID LKB1 PATHWAY LKB1 signaling events
0.1 1.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 4.6 PID RAS PATHWAY Regulation of Ras family activation
0.1 2.9 PID BARD1 PATHWAY BARD1 signaling events
0.1 6.1 PID NOTCH PATHWAY Notch signaling pathway
0.1 3.1 PID AURORA A PATHWAY Aurora A signaling
0.1 2.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 2.8 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 2.4 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 1.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.9 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 1.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 10.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.1 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 3.6 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.1 PID ATR PATHWAY ATR signaling pathway
0.0 1.0 PID CD40 PATHWAY CD40/CD40L signaling
0.0 1.4 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.7 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.5 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 2.2 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.6 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.6 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 3.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.9 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.6 PID SHP2 PATHWAY SHP2 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 19.0 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.5 8.7 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.4 9.6 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.4 6.4 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.3 7.9 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.2 3.1 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 3.9 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 3.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 1.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 2.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 3.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 1.9 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 1.0 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 2.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 1.9 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.6 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 1.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.6 REACTOME KINESINS Genes involved in Kinesins
0.0 1.8 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.5 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.9 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 1.3 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 1.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.7 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.7 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.3 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 1.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.2 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.4 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.3 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.4 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 1.4 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.6 REACTOME FRS2 MEDIATED CASCADE Genes involved in FRS2-mediated cascade
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease