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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for EGR1_EGR4

Z-value: 0.50

Motif logo

Transcription factors associated with EGR1_EGR4

Gene Symbol Gene ID Gene Info
ENSG00000120738.8 EGR1
ENSG00000135625.8 EGR4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EGR1hg38_v1_chr5_+_138465472_1384654870.173.8e-01Click!
EGR4hg38_v1_chr2_-_73293538_732937010.067.7e-01Click!

Activity profile of EGR1_EGR4 motif

Sorted Z-values of EGR1_EGR4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of EGR1_EGR4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_-_9129085 1.31 ENST00000377411.5
G protein-coupled receptor 157
chr21_-_6467509 0.76 ENST00000624406.3
ENST00000398168.5
ENST00000624934.3
cystathionine beta-synthase like
chr20_+_59577463 0.70 ENST00000359926.7
phosphatase and actin regulator 3
chr19_-_51002527 0.67 ENST00000595238.1
ENST00000600767.5
kallikrein related peptidase 8
chr1_-_93847150 0.58 ENST00000370244.5
BCAR3 adaptor protein, NSP family member
chr11_+_65919261 0.57 ENST00000525501.5
DR1 associated protein 1
chr9_+_87497852 0.53 ENST00000408954.8
death associated protein kinase 1
chr9_+_87497222 0.51 ENST00000358077.9
death associated protein kinase 1
chr9_+_17579059 0.51 ENST00000380607.5
SH3 domain containing GRB2 like 2, endophilin A1
chr2_+_30231524 0.50 ENST00000395323.9
ENST00000406087.5
ENST00000404397.5
LBH regulator of WNT signaling pathway
chr19_-_50968775 0.50 ENST00000391808.5
kallikrein related peptidase 6
chr1_-_109740304 0.49 ENST00000540225.2
glutathione S-transferase mu 3
chr9_+_87498491 0.47 ENST00000622514.4
death associated protein kinase 1
chr15_+_39581068 0.44 ENST00000397591.2
ENST00000260356.6
thrombospondin 1
chr16_+_28822982 0.44 ENST00000336783.9
ENST00000340394.12
ENST00000325215.10
ENST00000382686.8
ENST00000395547.6
ENST00000564304.5
ataxin 2 like
chr1_+_109687834 0.44 ENST00000349334.7
ENST00000476065.6
ENST00000483399.6
ENST00000369819.2
glutathione S-transferase mu 1
chr5_+_151253171 0.43 ENST00000357164.4
GM2 ganglioside activator
chr5_-_177497561 0.43 ENST00000359895.6
ENST00000355572.6
ENST00000393551.5
ENST00000505074.5
ENST00000393546.8
ENST00000355841.7
PDZ and LIM domain 7
chr19_-_50968966 0.43 ENST00000376851.7
kallikrein related peptidase 6
chr20_+_59835853 0.42 ENST00000492611.5
phosphatase and actin regulator 3
chr19_+_680707 0.42 ENST00000592947.5
ENST00000588773.5
ENST00000591573.1
ENST00000605925.3
follistatin like 3
chr8_-_143568854 0.42 ENST00000524906.5
ENST00000532862.1
ENST00000534459.5
maestro heat like repeat family member 6
chr17_+_81035122 0.41 ENST00000321280.11
ENST00000575989.5
ENST00000428708.7
ENST00000575712.5
ENST00000575245.5
ENST00000435091.7
ENST00000321300.10
BAR/IMD domain containing adaptor protein 2
chr9_+_34989641 0.40 ENST00000453597.8
ENST00000312316.9
ENST00000458263.6
ENST00000537321.5
ENST00000682809.1
ENST00000684748.1
DnaJ heat shock protein family (Hsp40) member B5
chr12_+_57089094 0.40 ENST00000342556.6
ENST00000300131.8
NGFI-A binding protein 2
chr19_-_51723968 0.40 ENST00000222115.5
ENST00000540069.7
hyaluronan synthase 1
chr2_+_190880834 0.39 ENST00000338435.8
glutaminase
chr22_-_38317380 0.39 ENST00000413574.6
casein kinase 1 epsilon
chr15_-_29822077 0.38 ENST00000677774.1
tight junction protein 1
chr21_+_44455471 0.38 ENST00000291592.6
leucine rich repeat containing 3
chr21_-_43076362 0.37 ENST00000359624.7
ENST00000352178.9
cystathionine beta-synthase
chr15_-_89496574 0.37 ENST00000268122.9
Rh family C glycoprotein
chr5_-_173235194 0.36 ENST00000329198.5
ENST00000521848.1
NK2 homeobox 5
chr11_+_65919331 0.35 ENST00000376991.6
DR1 associated protein 1
chr22_-_38317423 0.35 ENST00000396832.6
ENST00000403904.5
ENST00000405675.7
casein kinase 1 epsilon
chr19_-_14112641 0.34 ENST00000536649.5
protein kinase cAMP-activated catalytic subunit alpha
chr7_-_44325490 0.34 ENST00000350811.7
calcium/calmodulin dependent protein kinase II beta
chr21_-_43075831 0.34 ENST00000398158.5
ENST00000398165.8
cystathionine beta-synthase
chr1_-_231040218 0.33 ENST00000366654.5
family with sequence similarity 89 member A
chr21_-_46228751 0.33 ENST00000450351.1
ENST00000397728.8
ENST00000522411.5
ENST00000356396.8
ENST00000457828.6
lanosterol synthase
chr12_-_76031588 0.32 ENST00000602540.5
pleckstrin homology like domain family A member 1
chr5_-_88883199 0.32 ENST00000514015.5
ENST00000503075.1
myocyte enhancer factor 2C
chr4_+_155758990 0.31 ENST00000505154.5
ENST00000652626.1
ENST00000502959.5
ENST00000264424.13
ENST00000505764.5
ENST00000507146.5
ENST00000503520.5
guanylate cyclase 1 soluble subunit beta 1
chr19_-_14090963 0.31 ENST00000269724.5
sterile alpha motif domain containing 1
chr9_+_87497675 0.31 ENST00000472284.5
ENST00000469640.6
death associated protein kinase 1
chr16_+_3020359 0.31 ENST00000341627.5
ENST00000326577.9
ENST00000575124.1
ENST00000575836.1
TNF receptor superfamily member 12A
chr6_+_85450033 0.30 ENST00000257770.8
ENST00000369646.7
5'-nucleotidase ecto
chr19_-_1863497 0.30 ENST00000617223.1
ENST00000250916.6
Kruppel like factor 16
chr15_-_29822028 0.29 ENST00000545208.6
tight junction protein 1
chr4_+_155666827 0.29 ENST00000511507.5
ENST00000506455.6
guanylate cyclase 1 soluble subunit alpha 1
chr3_-_127823177 0.29 ENST00000434178.6
monoglyceride lipase
chr2_+_218568865 0.29 ENST00000295701.9
CCR4-NOT transcription complex subunit 9
chr8_-_141000937 0.28 ENST00000520892.5
protein tyrosine kinase 2
chr14_+_51651858 0.28 ENST00000395718.6
FERM domain containing 6
chr2_+_190880809 0.28 ENST00000320717.8
glutaminase
chr11_+_65919480 0.28 ENST00000527119.5
DR1 associated protein 1
chr3_-_127823235 0.27 ENST00000398104.5
monoglyceride lipase
chr9_+_34652167 0.27 ENST00000441545.7
ENST00000553620.5
interleukin 11 receptor subunit alpha
chr16_+_28823212 0.27 ENST00000570200.5
ataxin 2 like
chr8_-_123396412 0.27 ENST00000287394.10
ATPase family AAA domain containing 2
chr3_-_13880059 0.26 ENST00000285018.5
Wnt family member 7A
chr5_-_173328407 0.26 ENST00000265087.9
stanniocalcin 2
chr19_+_676385 0.26 ENST00000166139.9
follistatin like 3
chr19_+_29811944 0.26 ENST00000262643.8
ENST00000575243.5
cyclin E1
chr12_-_84912816 0.26 ENST00000680469.1
ENST00000450363.4
ENST00000681106.1
solute carrier family 6 member 15
chr21_-_44261854 0.26 ENST00000431166.1
DNA methyltransferase 3 like
chr4_+_155666718 0.26 ENST00000621234.4
ENST00000511108.5
guanylate cyclase 1 soluble subunit alpha 1
chr14_-_100587404 0.25 ENST00000554140.2
brain enriched guanylate kinase associated
chr4_+_155666963 0.25 ENST00000455639.6
guanylate cyclase 1 soluble subunit alpha 1
chr14_+_51651901 0.25 ENST00000344768.10
FERM domain containing 6
chr7_-_130668705 0.25 ENST00000330992.8
ENST00000425248.5
COPI coat complex subunit gamma 2
chr6_+_151325665 0.25 ENST00000354675.10
A-kinase anchoring protein 12
chr4_+_155667096 0.25 ENST00000393832.7
guanylate cyclase 1 soluble subunit alpha 1
chr2_-_27495185 0.25 ENST00000264703.4
fibronectin type III domain containing 4
chr3_-_45226268 0.25 ENST00000503771.2
transmembrane protein 158
chr14_+_66508495 0.25 ENST00000543237.5
gephyrin
chr4_+_150078426 0.24 ENST00000296550.12
doublecortin like kinase 2
chr1_-_21937300 0.24 ENST00000374695.8
heparan sulfate proteoglycan 2
chr19_-_51065067 0.24 ENST00000595547.5
ENST00000335422.3
ENST00000595793.6
ENST00000596955.1
kallikrein related peptidase 13
chr12_+_53097656 0.24 ENST00000301464.4
insulin like growth factor binding protein 6
chr3_-_127822835 0.24 ENST00000453507.6
monoglyceride lipase
chr17_-_43546323 0.24 ENST00000545954.5
ENST00000319349.10
ETS variant transcription factor 4
chr4_+_155667198 0.23 ENST00000296518.11
guanylate cyclase 1 soluble subunit alpha 1
chr21_-_44261884 0.23 ENST00000628202.3
DNA methyltransferase 3 like
chr19_-_15200902 0.23 ENST00000601011.1
ENST00000263388.7
notch receptor 3
chr1_+_156106698 0.23 ENST00000675667.1
lamin A/C
chr12_-_84912783 0.23 ENST00000680892.1
ENST00000266682.10
ENST00000680714.1
ENST00000552192.5
solute carrier family 6 member 15
chr14_+_66508127 0.22 ENST00000459628.5
ENST00000478722.6
gephyrin
chr9_-_75028274 0.22 ENST00000376834.8
carnosine N-methyltransferase 1
chr20_+_1894462 0.22 ENST00000622179.4
signal regulatory protein alpha
chr10_+_127907036 0.22 ENST00000254667.8
ENST00000442830.5
protein tyrosine phosphatase receptor type E
chrX_+_136147465 0.22 ENST00000651929.2
four and a half LIM domains 1
chr12_+_70366277 0.22 ENST00000258111.5
potassium calcium-activated channel subfamily M regulatory beta subunit 4
chrX_-_48957027 0.22 ENST00000455452.5
OTU deubiquitinase 5
chr16_-_352714 0.22 ENST00000262320.8
axin 1
chr21_-_44262216 0.22 ENST00000270172.7
DNA methyltransferase 3 like
chr16_+_788614 0.22 ENST00000262315.14
ENST00000455171.6
ENST00000317063.10
chromosome transmission fidelity factor 18
chr11_-_107858777 0.22 ENST00000525815.6
solute carrier family 35 member F2
chrX_+_136147556 0.21 ENST00000651089.1
ENST00000420362.5
four and a half LIM domains 1
chr14_+_85533167 0.21 ENST00000682132.1
fibronectin leucine rich transmembrane protein 2
chr3_-_197749688 0.21 ENST00000273582.9
rubicon autophagy regulator
chr16_+_58463663 0.21 ENST00000258187.9
NDRG family member 4
chr11_+_119206298 0.21 ENST00000634586.1
ENST00000634840.1
ENST00000264033.6
ENST00000637974.1
Cbl proto-oncogene
chrX_+_136147525 0.21 ENST00000652745.1
ENST00000627578.2
ENST00000652457.1
ENST00000394155.8
ENST00000618438.4
four and a half LIM domains 1
chr1_+_26280059 0.21 ENST00000270792.10
SH3 domain binding glutamate rich protein like 3
chr1_+_109687789 0.20 ENST00000309851.10
ENST00000369823.6
glutathione S-transferase mu 1
chr14_-_91253925 0.20 ENST00000531499.2
G protein-coupled receptor 68
chr1_-_85276467 0.20 ENST00000648566.1
BCL10 immune signaling adaptor
chr2_-_191150971 0.20 ENST00000409995.5
ENST00000392320.7
signal transducer and activator of transcription 4
chr7_-_92833896 0.20 ENST00000265734.8
cyclin dependent kinase 6
chr15_+_41774539 0.20 ENST00000514566.5
mitogen-activated protein kinase binding protein 1
chr17_+_77140898 0.20 ENST00000585618.5
SEC14 like lipid binding 1
chr5_-_141618914 0.20 ENST00000518047.5
diaphanous related formin 1
chr10_+_3104676 0.20 ENST00000415005.6
ENST00000468050.1
phosphofructokinase, platelet
chr7_-_101165114 0.19 ENST00000445482.2
VGF nerve growth factor inducible
chr20_+_43457885 0.19 ENST00000668808.1
ENST00000670741.1
ENST00000662078.1
ENST00000244020.5
ENST00000657241.1
serine and arginine rich splicing factor 6
novel protein
chr1_-_20486197 0.19 ENST00000375078.4
calcium/calmodulin dependent protein kinase II inhibitor 1
chr3_+_197749855 0.19 ENST00000241502.9
forty-two-three domain containing 1
chrX_-_48957548 0.19 ENST00000376488.8
ENST00000396743.7
ENST00000156084.8
OTU deubiquitinase 5
chr16_+_29806078 0.19 ENST00000545521.5
MYC associated zinc finger protein
chr19_+_45340760 0.19 ENST00000585434.5
kinesin light chain 3
chr19_+_45340736 0.19 ENST00000391946.7
kinesin light chain 3
chr22_-_30326923 0.19 ENST00000215790.12
TBC1 domain family member 10A
chr5_-_141619049 0.19 ENST00000647433.1
ENST00000253811.10
ENST00000389057.9
ENST00000398557.8
diaphanous related formin 1
chr7_-_101217569 0.19 ENST00000223127.8
procollagen-lysine,2-oxoglutarate 5-dioxygenase 3
chr16_-_88785210 0.19 ENST00000301015.14
piezo type mechanosensitive ion channel component 1
chr12_-_109880421 0.18 ENST00000544393.5
glycolipid transfer protein
chr9_-_34637800 0.18 ENST00000680730.1
ENST00000477726.1
sigma non-opioid intracellular receptor 1
chr2_+_48314637 0.18 ENST00000413569.5
ENST00000340553.8
forkhead box N2
chr16_+_30183595 0.18 ENST00000219150.10
ENST00000570045.5
ENST00000565497.5
ENST00000570244.5
coronin 1A
chr22_-_30326877 0.18 ENST00000403477.7
TBC1 domain family member 10A
chr3_-_171460063 0.18 ENST00000284483.12
ENST00000475336.5
ENST00000357327.9
ENST00000460047.5
ENST00000488470.5
ENST00000470834.5
TRAF2 and NCK interacting kinase
chr13_-_20161038 0.18 ENST00000241125.4
gap junction protein alpha 3
chr15_-_79971164 0.18 ENST00000335661.6
ENST00000267953.4
ENST00000677151.1
BCL2 related protein A1
chr12_+_113358542 0.18 ENST00000545182.6
ENST00000280800.5
phospholipase B domain containing 2
chr2_-_40452008 0.18 ENST00000417271.1
solute carrier family 8 member A1
chr6_+_157823191 0.18 ENST00000681534.1
ENST00000681183.1
ENST00000679732.1
ENST00000681186.1
ENST00000680078.1
ENST00000681138.1
ENST00000680495.1
ENST00000392185.8
sorting nexin 9
chr11_-_64778747 0.18 ENST00000227503.13
ENST00000377394.7
ENST00000334944.9
splicing factor 1
chr19_-_40690553 0.18 ENST00000598779.5
NUMB like endocytic adaptor protein
chr1_+_26280117 0.18 ENST00000319041.6
SH3 domain binding glutamate rich protein like 3
chr6_-_111873421 0.18 ENST00000368678.8
ENST00000523238.5
ENST00000354650.7
FYN proto-oncogene, Src family tyrosine kinase
chr11_-_64745331 0.17 ENST00000377489.5
ENST00000354024.7
RAS guanyl releasing protein 2
chr14_+_93347168 0.17 ENST00000342144.3
cytochrome c oxidase subunit 8C
chr9_-_34637719 0.17 ENST00000378892.5
ENST00000680277.1
ENST00000277010.9
ENST00000679597.1
ENST00000680244.1
sigma non-opioid intracellular receptor 1
chr11_-_66958366 0.17 ENST00000651036.1
ENST00000652125.1
ENST00000531614.6
ENST00000524491.6
ENST00000529047.6
ENST00000393960.7
ENST00000393958.7
ENST00000528403.6
ENST00000651854.1
pyruvate carboxylase
chr17_-_38825303 0.17 ENST00000614790.5
CWC25 spliceosome associated protein homolog
chr1_-_37808168 0.17 ENST00000373044.3
yrdC N6-threonylcarbamoyltransferase domain containing
chr2_+_190343561 0.17 ENST00000322522.8
ENST00000392329.7
ENST00000430311.5
inositol polyphosphate-1-phosphatase
chr12_-_48957365 0.17 ENST00000398092.4
ENST00000539611.1
novel protein
ADP ribosylation factor 3
chr19_-_2151525 0.17 ENST00000345016.9
ENST00000643116.3
adaptor related protein complex 3 subunit delta 1
chr1_+_25616780 0.17 ENST00000374332.9
mannosidase alpha class 1C member 1
chr6_+_36027773 0.17 ENST00000468133.5
mitogen-activated protein kinase 14
chr6_+_43771960 0.16 ENST00000230480.10
vascular endothelial growth factor A
chr8_-_126558461 0.16 ENST00000304916.4
LRAT domain containing 2
chr17_-_42181116 0.16 ENST00000264661.4
potassium voltage-gated channel subfamily H member 4
chr14_+_64504574 0.16 ENST00000358738.3
zinc finger and BTB domain containing 1
chr5_-_141618957 0.16 ENST00000389054.8
diaphanous related formin 1
chr17_-_44385332 0.16 ENST00000648408.1
integrin subunit alpha 2b
chr11_+_35943981 0.16 ENST00000528989.5
ENST00000524419.5
ENST00000315571.6
low density lipoprotein receptor class A domain containing 3
chr19_+_53869384 0.16 ENST00000391769.2
myeloid associated differentiation marker
chr17_+_62627628 0.16 ENST00000303375.10
mannose receptor C type 2
chr3_-_171460368 0.16 ENST00000436636.7
ENST00000465393.1
ENST00000341852.10
TRAF2 and NCK interacting kinase
chr3_-_125055987 0.16 ENST00000311127.9
heart development protein with EGF like domains 1
chr2_-_225042433 0.16 ENST00000258390.12
dedicator of cytokinesis 10
chr5_-_131797030 0.16 ENST00000615660.4
folliculin interacting protein 1
chr5_-_177496845 0.16 ENST00000506537.1
PDZ and LIM domain 7
chr22_+_38201932 0.15 ENST00000538999.1
ENST00000538320.5
ENST00000338483.7
ENST00000441709.1
MAF bZIP transcription factor F
chr19_-_40690629 0.15 ENST00000252891.8
NUMB like endocytic adaptor protein
chr6_+_15248855 0.15 ENST00000397311.4
jumonji and AT-rich interaction domain containing 2
chr12_-_32896757 0.15 ENST00000070846.11
ENST00000340811.9
plakophilin 2
chr4_+_165873231 0.15 ENST00000061240.7
tolloid like 1
chr19_+_16067526 0.15 ENST00000646974.2
tropomyosin 4
chr17_-_41624541 0.15 ENST00000540235.5
ENST00000311208.13
keratin 17
chr20_+_1894733 0.15 ENST00000356025.7
signal regulatory protein alpha
chr16_+_81314922 0.15 ENST00000648994.2
gigaxonin
chr9_-_4666495 0.15 ENST00000475086.5
spermatogenesis associated 6 like
chr11_-_68213577 0.15 ENST00000402789.5
ENST00000402185.6
ENST00000458496.1
lysine methyltransferase 5B
chr11_-_73761051 0.15 ENST00000336083.8
ENST00000536566.5
ENST00000541588.5
ENST00000540771.5
ENST00000310653.10
RAB6A, member RAS oncogene family
chr1_+_34781174 0.15 ENST00000373366.3
gap junction protein beta 3
chr19_-_50333504 0.15 ENST00000474951.1
potassium voltage-gated channel subfamily C member 3
chr11_-_61816985 0.15 ENST00000350997.12
fatty acid desaturase 1
chr17_-_7251691 0.15 ENST00000574322.6
CTD nuclear envelope phosphatase 1
chr15_-_29822418 0.15 ENST00000614355.5
ENST00000495972.6
ENST00000346128.10
tight junction protein 1
chr1_+_25819926 0.15 ENST00000533762.5
ENST00000529116.5
ENST00000474295.5
ENST00000488327.6
ENST00000472643.5
ENST00000374303.7
ENST00000526894.5
ENST00000524618.5
ENST00000374307.9
mitochondrial fission regulator 1 like
chr6_+_157823367 0.15 ENST00000679691.1
sorting nexin 9
chr17_-_44324770 0.15 ENST00000592857.5
ENST00000586016.5
ENST00000590194.5
ENST00000588049.5
ENST00000586633.5
ENST00000377095.10
ENST00000537904.6
ENST00000585636.5
ENST00000585523.1
ENST00000225308.12
solute carrier family 25 member 39
chr1_-_111449209 0.14 ENST00000235090.10
WD repeat domain 77
chr17_-_42181081 0.14 ENST00000607371.5
potassium voltage-gated channel subfamily H member 4
chr11_-_62545629 0.14 ENST00000528508.5
ENST00000533365.5
AHNAK nucleoprotein
chr17_+_32486975 0.14 ENST00000313401.4
cyclin dependent kinase 5 regulatory subunit 1
chr1_-_25859352 0.14 ENST00000374298.4
ENST00000538789.5
aurora kinase A and ninein interacting protein
chr14_-_68979076 0.14 ENST00000538545.6
ENST00000684639.1
actinin alpha 1
chr1_-_84690255 0.14 ENST00000603677.1
SSX family member 2 interacting protein
chr11_-_64778502 0.14 ENST00000681407.1
ENST00000377390.8
splicing factor 1
chr10_-_43267059 0.14 ENST00000395810.6
RasGEF domain family member 1A
chr20_-_4015518 0.14 ENST00000545616.2
ENST00000358395.11
ring finger protein 24
chr1_+_202462730 0.14 ENST00000290419.9
ENST00000491336.5
protein phosphatase 1 regulatory subunit 12B
chr8_+_32548210 0.14 ENST00000523079.5
ENST00000650919.1
neuregulin 1
chr11_-_64778469 0.14 ENST00000377387.5
splicing factor 1
chr20_+_1895365 0.14 ENST00000358771.5
signal regulatory protein alpha

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0070458 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.2 1.5 GO:0006535 cysteine biosynthetic process from serine(GO:0006535)
0.2 0.8 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.2 0.5 GO:0018315 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.1 0.4 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of cGMP-mediated signaling(GO:0010752)
0.1 0.4 GO:0003162 atrioventricular node development(GO:0003162)
0.1 0.7 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 0.3 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.1 0.5 GO:1904674 positive regulation of somatic stem cell population maintenance(GO:1904674)
0.1 0.4 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.5 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1 0.3 GO:0060823 canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823)
0.1 0.5 GO:0003383 apical constriction(GO:0003383)
0.1 0.9 GO:0071926 endocannabinoid signaling pathway(GO:0071926)
0.1 0.4 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.1 0.7 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.1 0.4 GO:0060988 lipid tube assembly(GO:0060988)
0.1 1.5 GO:0060019 radial glial cell differentiation(GO:0060019)
0.1 0.4 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) positive regulation of interleukin-12 secretion(GO:2001184)
0.1 0.3 GO:2000327 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.1 0.2 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1 1.8 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.1 0.3 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1 0.4 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.1 0.5 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.2 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.1 0.2 GO:0003169 coronary vein morphogenesis(GO:0003169) regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 0.4 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.3 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 0.2 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 0.2 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.2 GO:0042418 epinephrine biosynthetic process(GO:0042418)
0.1 0.2 GO:0032765 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906) positive regulation of mast cell cytokine production(GO:0032765)
0.1 0.3 GO:0046086 AMP catabolic process(GO:0006196) adenosine biosynthetic process(GO:0046086)
0.0 0.9 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.4 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.3 GO:1904978 regulation of endosome organization(GO:1904978)
0.0 0.1 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.0 0.2 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.2 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.0 0.2 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.1 GO:1903947 positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
0.0 0.1 GO:0035498 carnosine metabolic process(GO:0035498)
0.0 0.1 GO:2000174 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.0 0.4 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.0 0.5 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.2 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.5 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.2 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.0 0.6 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.2 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.0 0.2 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.1 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
0.0 0.2 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.3 GO:0007068 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.0 0.2 GO:0009635 response to herbicide(GO:0009635)
0.0 0.1 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.3 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.0 0.1 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.2 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.0 GO:0007521 muscle cell fate determination(GO:0007521)
0.0 0.1 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 0.1 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.0 0.1 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.8 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.1 GO:0019858 cytosine metabolic process(GO:0019858)
0.0 0.1 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.6 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.1 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.0 0.1 GO:0019046 release from viral latency(GO:0019046)
0.0 0.3 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.2 GO:0072104 glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.0 0.7 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.1 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.0 0.1 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 0.1 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.0 0.4 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.5 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.3 GO:0046836 glycolipid transport(GO:0046836)
0.0 0.4 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.0 0.2 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.2 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.5 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.2 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.1 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473) retinal cell apoptotic process(GO:1990009)
0.0 0.2 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.0 0.1 GO:0072209 positive regulation of glomerular filtration(GO:0003104) metanephric mesangial cell differentiation(GO:0072209) metanephric glomerular mesangial cell differentiation(GO:0072254)
0.0 0.1 GO:0052552 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.0 0.1 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.0 0.1 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340) regulation of embryonic cell shape(GO:0016476)
0.0 0.2 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.2 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0 0.1 GO:0099557 trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission(GO:0099557)
0.0 0.1 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.0 0.1 GO:0034970 regulation of growth plate cartilage chondrocyte proliferation(GO:0003420) histone H3-R2 methylation(GO:0034970)
0.0 0.2 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.0 GO:0060025 regulation of synaptic activity(GO:0060025)
0.0 0.1 GO:0072156 distal tubule morphogenesis(GO:0072156) metanephric proximal tubule development(GO:0072237)
0.0 0.2 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.1 GO:1904580 regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582)
0.0 0.1 GO:0061184 positive regulation of dermatome development(GO:0061184)
0.0 0.1 GO:1904021 negative regulation of G-protein coupled receptor internalization(GO:1904021)
0.0 0.6 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.0 0.1 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.2 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.1 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.3 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.1 GO:0006258 UDP-glucose catabolic process(GO:0006258) negative regulation of type B pancreatic cell development(GO:2000077)
0.0 0.1 GO:0042946 glucoside transport(GO:0042946) glycoside transport(GO:1901656)
0.0 0.1 GO:0036116 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 0.3 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:0090096 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.0 0.3 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.0 GO:0090135 actin filament branching(GO:0090135)
0.0 0.0 GO:0042662 negative regulation of cell fate specification(GO:0009996) negative regulation of mesodermal cell fate specification(GO:0042662)
0.0 0.1 GO:0006850 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.0 0.3 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.1 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0 0.1 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.0 0.1 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.0 0.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.1 GO:0097360 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.0 0.1 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.2 GO:0071313 cellular response to caffeine(GO:0071313)
0.0 0.1 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.0 0.1 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.3 GO:0090205 positive regulation of cholesterol metabolic process(GO:0090205)
0.0 0.2 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.4 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.2 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.1 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.1 GO:0008355 olfactory learning(GO:0008355)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.1 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.0 0.1 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.1 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.3 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.6 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.1 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.0 0.1 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.0 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 0.1 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.2 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.3 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.0 0.2 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.0 0.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.2 GO:0038129 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.0 0.0 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.0 0.3 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.1 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.5 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.0 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0 0.1 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.0 0.1 GO:1900454 positive regulation of norepinephrine secretion(GO:0010701) positive regulation of long term synaptic depression(GO:1900454)
0.0 0.2 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.0 0.1 GO:0030821 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821)
0.0 0.2 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.1 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.2 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.1 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.0 0.1 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0 0.1 GO:1903182 regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
0.0 0.1 GO:0071321 cellular response to cGMP(GO:0071321)
0.0 0.1 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0 0.2 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.2 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.1 GO:1902162 platelet alpha granule organization(GO:0070889) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.0 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.0 0.0 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.0 0.0 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.0 0.1 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.0 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.0 0.3 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0 0.1 GO:1900242 regulation of synaptic vesicle endocytosis(GO:1900242)
0.0 0.2 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.0 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.3 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.4 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.0 GO:1904761 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760) negative regulation of myofibroblast differentiation(GO:1904761)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.3 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 0.1 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.1 GO:0038026 glycoprotein transport(GO:0034436) reelin-mediated signaling pathway(GO:0038026)
0.0 0.2 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.0 0.0 GO:0003358 noradrenergic neuron development(GO:0003358)
0.0 0.1 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.1 0.2 GO:0036284 tubulobulbar complex(GO:0036284)
0.0 0.5 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.1 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.2 GO:0032449 CBM complex(GO:0032449)
0.0 0.4 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.2 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.4 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.2 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.1 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.3 GO:0061574 ASAP complex(GO:0061574)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.5 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 1.1 GO:0005921 gap junction(GO:0005921)
0.0 0.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.2 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.1 GO:0044308 axonal spine(GO:0044308)
0.0 0.5 GO:0031143 pseudopodium(GO:0031143)
0.0 0.2 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.3 GO:0016600 flotillin complex(GO:0016600)
0.0 0.0 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0090661 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.0 GO:0043293 apoptosome(GO:0043293)
0.0 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 1.5 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:1990356 sumoylated E2 ligase complex(GO:1990356)
0.0 0.1 GO:0005873 plus-end kinesin complex(GO:0005873)
0.0 0.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.1 GO:0043196 varicosity(GO:0043196)
0.0 0.0 GO:0030849 autosome(GO:0030849)
0.0 0.1 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 1.4 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.1 GO:0035859 Seh1-associated complex(GO:0035859)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 1.2 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.2 0.5 GO:0061598 nitrate reductase activity(GO:0008940) molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.2 0.5 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 0.4 GO:0070052 collagen V binding(GO:0070052)
0.1 0.4 GO:0030290 sphingolipid activator protein activity(GO:0030290) beta-N-acetylgalactosaminidase activity(GO:0032428)
0.1 0.7 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.5 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.1 0.4 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.4 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.3 GO:0017089 glycolipid transporter activity(GO:0017089)
0.1 0.2 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.1 1.1 GO:0043295 glutathione binding(GO:0043295)
0.1 0.2 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.1 0.3 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.1 0.3 GO:0039552 RIG-I binding(GO:0039552)
0.1 0.3 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.1 GO:0070704 C-5 sterol desaturase activity(GO:0000248) sterol desaturase activity(GO:0070704)
0.0 0.2 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.2 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.1 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.0 0.9 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.5 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:0000247 C-8 sterol isomerase activity(GO:0000247)
0.0 0.2 GO:0070051 fibrinogen binding(GO:0070051)
0.0 1.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.2 GO:0032810 sterol response element binding(GO:0032810)
0.0 0.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.2 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.1 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.0 0.8 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0031687 A2A adenosine receptor binding(GO:0031687)
0.0 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.0 0.3 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.6 GO:0048185 activin binding(GO:0048185)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.6 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.5 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.2 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.1 GO:0042947 glucoside transmembrane transporter activity(GO:0042947)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.9 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.6 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.4 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.0 0.2 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.1 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.2 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.3 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.4 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.0 GO:0000994 RNA polymerase III core binding(GO:0000994)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.2 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.2 GO:0009374 biotin binding(GO:0009374)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.6 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.0 0.1 GO:0005471 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.0 0.2 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.0 GO:0008988 rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.1 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.2 GO:0016866 intramolecular transferase activity(GO:0016866)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.1 GO:0008430 selenium binding(GO:0008430)
0.0 0.1 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.0 0.1 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.3 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.3 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.4 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.0 GO:0098918 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.0 0.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0001129 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.0 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.0 GO:0008893 guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity(GO:0008893) diphosphoric monoester hydrolase activity(GO:0016794)
0.0 0.1 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 2.6 PID IFNG PATHWAY IFN-gamma pathway
0.0 1.6 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.4 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.1 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.2 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.8 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.0 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.0 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.7 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.1 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.6 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.8 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 1.0 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.1 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.0 0.8 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.9 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.6 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.0 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.5 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.9 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.5 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.4 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.9 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.0 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.4 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression