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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for EN1_ESX1_GBX1

Z-value: 0.74

Motif logo

Transcription factors associated with EN1_ESX1_GBX1

Gene Symbol Gene ID Gene Info
ENSG00000163064.7 EN1
ENSG00000123576.5 ESX1
ENSG00000164900.5 GBX1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ESX1hg38_v1_chrX_-_104254921_104254936-0.144.7e-01Click!
EN1hg38_v1_chr2_-_118847638_118847654-0.134.9e-01Click!
GBX1hg38_v1_chr7_-_151167692_1511676970.057.8e-01Click!

Activity profile of EN1_ESX1_GBX1 motif

Sorted Z-values of EN1_ESX1_GBX1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of EN1_ESX1_GBX1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_-_16978276 3.84 ENST00000375534.7
microfibril associated protein 2
chr4_+_168092530 2.55 ENST00000359299.8
annexin A10
chr3_+_111999326 1.43 ENST00000494932.1
transgelin 3
chr6_+_130018565 1.36 ENST00000361794.7
ENST00000526087.5
ENST00000533560.5
L3MBTL histone methyl-lysine binding protein 3
chr3_-_195811889 1.36 ENST00000475231.5
mucin 4, cell surface associated
chr12_-_27970047 1.26 ENST00000395868.7
parathyroid hormone like hormone
chr3_-_74521140 1.18 ENST00000263665.6
contactin 3
chr3_-_195811857 1.14 ENST00000349607.8
ENST00000346145.8
mucin 4, cell surface associated
chr3_-_195811916 1.14 ENST00000463781.8
mucin 4, cell surface associated
chr12_-_27970273 1.00 ENST00000542963.1
ENST00000535992.5
parathyroid hormone like hormone
chr2_+_157257687 0.97 ENST00000259056.5
polypeptide N-acetylgalactosaminyltransferase 5
chr5_+_136059151 0.92 ENST00000503087.1
transforming growth factor beta induced
chr8_+_7881387 0.89 ENST00000314357.4
defensin beta 103A
chr6_+_26199509 0.89 ENST00000356530.5
H2B clustered histone 7
chr10_-_29736956 0.84 ENST00000674475.1
supervillin
chr11_-_101129806 0.83 ENST00000325455.10
ENST00000617858.4
ENST00000619228.2
progesterone receptor
chr3_+_111998739 0.82 ENST00000393917.6
ENST00000273368.8
transgelin 3
chr5_+_31193739 0.81 ENST00000514738.5
cadherin 6
chr3_+_111999189 0.78 ENST00000455401.6
transgelin 3
chr19_+_44905785 0.77 ENST00000446996.5
ENST00000252486.9
ENST00000434152.5
apolipoprotein E
chr5_+_151259793 0.76 ENST00000523004.1
GM2 ganglioside activator
chr3_-_142029108 0.76 ENST00000497579.5
transcription factor Dp-2
chr16_-_55833085 0.74 ENST00000360526.8
carboxylesterase 1
chr1_-_74733253 0.72 ENST00000417775.5
crystallin zeta
chr3_+_111998915 0.70 ENST00000478951.6
transgelin 3
chr12_+_26195313 0.70 ENST00000422622.3
sarcospan
chr3_+_122055355 0.68 ENST00000330540.7
ENST00000469710.5
ENST00000493101.5
CD86 molecule
chrX_+_7219431 0.65 ENST00000674499.1
ENST00000217961.5
steroid sulfatase
chr4_-_56681588 0.65 ENST00000554144.5
ENST00000381260.7
HOP homeobox
chr3_-_138329839 0.63 ENST00000333911.9
ENST00000383180.6
NME/NM23 family member 9
chr4_-_56681288 0.63 ENST00000556376.6
ENST00000420433.6
HOP homeobox
chr1_+_209704836 0.63 ENST00000367027.5
hydroxysteroid 11-beta dehydrogenase 1
chr17_-_40755328 0.62 ENST00000312150.5
keratin 25
chr5_+_31193678 0.61 ENST00000265071.3
cadherin 6
chr2_-_207167220 0.61 ENST00000421199.5
ENST00000457962.5
Kruppel like factor 7
chr2_-_187554351 0.60 ENST00000437725.5
ENST00000409676.5
ENST00000233156.9
ENST00000339091.8
ENST00000420747.1
tissue factor pathway inhibitor
chr17_-_41055211 0.60 ENST00000542910.1
ENST00000398477.1
keratin associated protein 2-2
chr11_-_18236795 0.60 ENST00000278222.7
serum amyloid A4, constitutive
chr6_-_110179995 0.59 ENST00000392586.5
ENST00000419252.1
ENST00000359451.6
ENST00000392588.5
WASP family member 1
chr10_-_49762276 0.57 ENST00000374103.9
oxoglutarate dehydrogenase L
chr12_-_10802627 0.57 ENST00000240687.2
taste 2 receptor member 7
chr1_+_202348687 0.56 ENST00000608999.6
ENST00000391959.5
ENST00000480184.5
protein phosphatase 1 regulatory subunit 12B
chr12_-_10826358 0.55 ENST00000240619.2
taste 2 receptor member 10
chr6_-_111759053 0.54 ENST00000462856.6
ENST00000229471.8
FYN proto-oncogene, Src family tyrosine kinase
chr4_-_67883987 0.54 ENST00000283916.11
transmembrane serine protease 11D
chr8_-_42377227 0.53 ENST00000220812.3
dickkopf WNT signaling pathway inhibitor 4
chr10_-_49762335 0.51 ENST00000419399.4
ENST00000432695.2
oxoglutarate dehydrogenase L
chr12_-_9869345 0.48 ENST00000228438.3
C-type lectin domain family 2 member B
chr1_-_201171545 0.48 ENST00000367333.6
transmembrane protein 9
chr12_+_26195543 0.47 ENST00000242729.7
sarcospan
chr7_+_130344810 0.47 ENST00000497503.5
ENST00000463587.5
ENST00000461828.5
ENST00000474905.6
ENST00000494311.1
ENST00000466363.6
carboxypeptidase A5
chr14_+_21841182 0.46 ENST00000390433.1
T cell receptor alpha variable 12-1
chr6_-_39725387 0.45 ENST00000287152.12
kinesin family member 6
chr14_+_74348440 0.43 ENST00000256362.5
vertebrae development associated
chr3_+_155080307 0.43 ENST00000360490.7
membrane metalloendopeptidase
chr15_+_88621290 0.42 ENST00000332810.4
ENST00000559528.1
apoptosis enhancing nuclease
chr1_+_27934980 0.42 ENST00000373894.8
sphingomyelin phosphodiesterase acid like 3B
chr19_+_7030578 0.42 ENST00000329753.5
methyl-CpG binding domain protein 3 like 5
chr5_+_177384430 0.42 ENST00000512593.5
ENST00000324417.6
solute carrier family 34 member 1
chr20_-_37261808 0.42 ENST00000373614.7
growth hormone releasing hormone
chr18_+_58221535 0.41 ENST00000431212.6
ENST00000586268.5
ENST00000587190.5
NEDD4 like E3 ubiquitin protein ligase
chr2_+_186694007 0.41 ENST00000304698.10
family with sequence similarity 171 member B
chr20_-_52105644 0.41 ENST00000371523.8
ZFP64 zinc finger protein
chr1_+_160190567 0.40 ENST00000368078.8
calsequestrin 1
chr9_+_72577369 0.40 ENST00000651183.1
transmembrane channel like 1
chr18_+_61333424 0.40 ENST00000262717.9
cadherin 20
chr1_+_27935110 0.40 ENST00000549094.1
sphingomyelin phosphodiesterase acid like 3B
chr11_-_101129706 0.40 ENST00000534013.5
progesterone receptor
chr15_-_41972504 0.39 ENST00000220325.9
EH domain containing 4
chr6_-_26199272 0.39 ENST00000650491.1
ENST00000635200.1
ENST00000341023.2
novel protein
H2A clustered histone 7
chr14_+_22271921 0.38 ENST00000390464.2
T cell receptor alpha variable 38-1
chr7_-_101217569 0.38 ENST00000223127.8
procollagen-lysine,2-oxoglutarate 5-dioxygenase 3
chr12_-_21910853 0.37 ENST00000544039.5
ATP binding cassette subfamily C member 9
chr12_+_107318395 0.37 ENST00000420571.6
ENST00000280758.10
BTB domain containing 11
chr11_-_125111579 0.37 ENST00000532156.5
ENST00000532407.5
ENST00000279968.8
ENST00000527766.5
ENST00000529583.5
ENST00000524373.5
ENST00000527271.5
ENST00000526175.5
ENST00000529609.5
ENST00000682305.1
ENST00000533273.1
transmembrane protein 218
chr6_-_127459364 0.37 ENST00000487331.2
ENST00000483725.8
KIAA0408
chr17_-_66229380 0.36 ENST00000205948.11
apolipoprotein H
chr5_-_83673544 0.36 ENST00000503117.1
ENST00000510978.5
hyaluronan and proteoglycan link protein 1
chr11_-_122116215 0.36 ENST00000560104.2
BH3-like motif containing, cell death inducer
chr12_+_119668109 0.36 ENST00000229328.10
ENST00000630317.1
protein kinase AMP-activated non-catalytic subunit beta 1
chr1_+_151060357 0.36 ENST00000368921.5
MLLT11 transcription factor 7 cofactor
chr20_-_57711536 0.36 ENST00000265626.8
prostate transmembrane protein, androgen induced 1
chr6_+_131250375 0.36 ENST00000474850.2
A-kinase anchoring protein 7
chrX_+_108045050 0.36 ENST00000458383.1
ENST00000217957.10
V-set and immunoglobulin domain containing 1
chr12_-_89352395 0.35 ENST00000308385.6
dual specificity phosphatase 6
chr5_-_147906530 0.35 ENST00000318315.5
ENST00000515291.1
chromosome 5 open reading frame 46
chr19_-_46634685 0.35 ENST00000300873.4
G protein subunit gamma 8
chr12_+_28257195 0.35 ENST00000381259.5
coiled-coil domain containing 91
chr2_+_170178136 0.35 ENST00000409044.7
ENST00000408978.9
myosin IIIB
chrX_-_18672101 0.35 ENST00000379984.4
retinoschisin 1
chr15_-_55270280 0.35 ENST00000564609.5
RAB27A, member RAS oncogene family
chr14_-_106038355 0.34 ENST00000390597.3
immunoglobulin heavy variable 2-5
chr12_-_47079926 0.34 ENST00000429635.1
ENST00000550413.2
adhesion molecule with Ig like domain 2
chr6_-_116545658 0.34 ENST00000368602.4
trafficking protein particle complex 3 like
chrX_+_101550537 0.34 ENST00000372829.8
armadillo repeat containing X-linked 1
chr4_-_142305935 0.33 ENST00000511838.5
inositol polyphosphate-4-phosphatase type II B
chr1_-_120054225 0.33 ENST00000602566.6
notch receptor 2
chr16_+_86566821 0.33 ENST00000649859.1
forkhead box C2
chr8_-_7385558 0.33 ENST00000400156.4
zinc finger protein 705G
chr21_+_30396030 0.33 ENST00000355459.4
keratin associated protein 13-1
chrX_+_108044967 0.33 ENST00000415430.7
V-set and immunoglobulin domain containing 1
chr12_-_10130241 0.32 ENST00000353231.9
ENST00000525605.1
C-type lectin domain containing 7A
chr17_-_59151794 0.32 ENST00000584089.1
spindle and kinetochore associated complex subunit 2
chr11_+_33039996 0.32 ENST00000432887.5
ENST00000528898.1
ENST00000531632.6
t-complex 11 like 1
chr4_-_76007501 0.32 ENST00000264888.6
C-X-C motif chemokine ligand 9
chr19_+_41363989 0.32 ENST00000413014.6
transmembrane protein 91
chr16_-_29899245 0.32 ENST00000537485.5
seizure related 6 homolog like 2
chr11_+_59436469 0.32 ENST00000641045.1
olfactory receptor family 5 subfamily A member 1
chr11_-_117876892 0.32 ENST00000539526.5
FXYD domain containing ion transport regulator 6
chr7_-_41703062 0.31 ENST00000242208.5
inhibin subunit beta A
chr17_-_81683659 0.31 ENST00000574938.5
ENST00000570561.5
ENST00000573392.5
ENST00000576135.5
ENST00000573715.2
ADP ribosylation factor like GTPase 16
chr15_-_55270874 0.31 ENST00000567380.5
ENST00000565972.5
ENST00000569493.5
RAB27A, member RAS oncogene family
chr7_-_23347704 0.31 ENST00000619562.4
insulin like growth factor 2 mRNA binding protein 3
chr17_-_9791586 0.31 ENST00000571134.2
dehydrogenase/reductase 7C
chr3_-_125055987 0.31 ENST00000311127.9
heart development protein with EGF like domains 1
chr11_-_117877463 0.31 ENST00000527717.5
FXYD domain containing ion transport regulator 6
chr12_-_10130143 0.31 ENST00000298523.9
ENST00000396484.6
ENST00000310002.4
ENST00000304084.13
C-type lectin domain containing 7A
chr9_+_107306459 0.31 ENST00000457811.1
RAD23 homolog B, nucleotide excision repair protein
chr4_-_108762964 0.31 ENST00000512646.5
ENST00000411864.6
ENST00000296486.8
ENST00000510706.5
ethanolamine-phosphate phospho-lyase
chr13_-_36214584 0.30 ENST00000317764.6
spermatogenesis and oogenesis specific basic helix-loop-helix 2
chr14_+_22281097 0.30 ENST00000390465.2
T cell receptor alpha variable 38-2/delta variable 8
chr7_+_130344837 0.30 ENST00000485477.5
ENST00000431780.6
carboxypeptidase A5
chr6_+_29099490 0.30 ENST00000641659.2
olfactory receptor family 2 subfamily J member 1
chr3_-_179266971 0.30 ENST00000349697.2
ENST00000497599.5
potassium calcium-activated channel subfamily M regulatory beta subunit 3
chr7_-_24980148 0.30 ENST00000313367.7
oxysterol binding protein like 3
chr19_-_3557563 0.30 ENST00000389395.7
ENST00000355415.7
major facilitator superfamily domain containing 12
chr19_-_7021431 0.30 ENST00000636986.2
ENST00000637800.1
methyl-CpG binding domain protein 3 like 2B
chr1_-_93681829 0.30 ENST00000260502.11
BCAR3 adaptor protein, NSP family member
chr6_+_26158115 0.30 ENST00000377777.5
ENST00000289316.2
H2B clustered histone 5
chr10_+_47322450 0.30 ENST00000581492.3
growth differentiation factor 2
chr11_+_75815180 0.30 ENST00000356136.8
UV radiation resistance associated
chr2_+_209579598 0.29 ENST00000445941.5
ENST00000673860.1
microtubule associated protein 2
chr4_-_8871817 0.29 ENST00000400677.5
H6 family homeobox 1
chr3_-_151316795 0.29 ENST00000260843.5
G protein-coupled receptor 87
chr3_-_187291882 0.29 ENST00000392470.6
ENST00000169293.10
ENST00000439271.1
ENST00000392472.6
ENST00000392475.2
mannan binding lectin serine peptidase 1
chr11_-_117876719 0.29 ENST00000529335.6
ENST00000260282.8
FXYD domain containing ion transport regulator 6
chr11_-_71821548 0.29 ENST00000525199.1
zinc finger protein 705E
chr10_-_54801179 0.29 ENST00000373955.5
protocadherin related 15
chr6_-_27912396 0.28 ENST00000303324.4
olfactory receptor family 2 subfamily B member 2
chr10_-_48605032 0.28 ENST00000249601.9
Rho GTPase activating protein 22
chr12_-_119803383 0.27 ENST00000392520.2
ENST00000678677.1
ENST00000679249.1
ENST00000676849.1
citron rho-interacting serine/threonine kinase
chr8_-_7430348 0.27 ENST00000318124.3
defensin beta 103B
chr12_-_89352487 0.27 ENST00000548755.1
ENST00000279488.8
dual specificity phosphatase 6
chr8_+_12108172 0.27 ENST00000400078.3
zinc finger protein 705D
chr19_-_51019699 0.26 ENST00000358789.8
kallikrein related peptidase 10
chr15_+_21579912 0.26 ENST00000628444.1
long intergenic non-protein coding RNA 2203
chr13_-_30306997 0.26 ENST00000380617.7
ENST00000441394.1
katanin catalytic subunit A1 like 1
chr18_+_36544544 0.26 ENST00000591635.5
formin homology 2 domain containing 3
chr17_-_41047267 0.26 ENST00000542137.1
ENST00000391419.3
keratin associated protein 2-1
chr19_-_14529193 0.26 ENST00000596853.6
ENST00000676515.1
ENST00000678338.1
ENST00000595992.6
ENST00000677848.1
ENST00000677762.1
ENST00000678009.1
ENST00000596075.2
ENST00000601533.6
ENST00000396969.8
ENST00000598692.2
ENST00000678098.1
DnaJ heat shock protein family (Hsp40) member B1
chr6_+_29170907 0.25 ENST00000641417.1
olfactory receptor family 2 subfamily J member 2
chr21_+_29130630 0.25 ENST00000399926.5
ENST00000399928.6
MAP3K7 C-terminal like
chr5_+_136058849 0.25 ENST00000508076.5
transforming growth factor beta induced
chr18_-_14132423 0.25 ENST00000589498.5
ENST00000590202.3
zinc finger protein 519
chr6_+_63521738 0.24 ENST00000648894.1
ENST00000639568.2
protein tyrosine phosphatase 4A1
chr5_-_9630351 0.24 ENST00000382492.4
taste 2 receptor member 1
chr4_-_115113614 0.24 ENST00000264363.7
N-deacetylase and N-sulfotransferase 4
chr1_-_117929557 0.24 ENST00000369442.3
ENST00000369443.10
ganglioside induced differentiation associated protein 2
chr8_-_18887018 0.24 ENST00000523619.5
pleckstrin and Sec7 domain containing 3
chr14_-_22957061 0.24 ENST00000557591.5
ENST00000541587.6
ENST00000490506.5
ENST00000554406.1
HAUS augmin like complex subunit 4
chr5_-_126595237 0.24 ENST00000637206.1
ENST00000553117.5
aldehyde dehydrogenase 7 family member A1
chr19_+_3762705 0.24 ENST00000589174.1
mitochondrial ribosomal protein L54
chr7_+_154305256 0.24 ENST00000619756.4
dipeptidyl peptidase like 6
chr7_-_73624492 0.23 ENST00000414749.6
ENST00000429400.6
ENST00000434326.5
ENST00000313375.8
ENST00000354613.5
ENST00000453275.1
MLX interacting protein like
chr16_-_20691256 0.23 ENST00000307493.8
acyl-CoA synthetase medium chain family member 1
chr8_+_7926337 0.23 ENST00000400120.3
zinc finger protein 705B
chr10_-_97687191 0.23 ENST00000370626.4
arginine vasopressin induced 1
chr6_+_29550407 0.23 ENST00000641137.1
olfactory receptor family 2 subfamily I member 1 pseudogene
chr3_+_130850585 0.23 ENST00000505330.5
ENST00000504381.5
ENST00000507488.6
ATPase secretory pathway Ca2+ transporting 1
chr17_-_40994159 0.23 ENST00000391586.3
keratin associated protein 3-3
chr14_+_32329341 0.23 ENST00000557354.5
ENST00000557102.1
ENST00000557272.1
A-kinase anchoring protein 6
chr22_-_18936142 0.22 ENST00000438924.5
ENST00000457083.1
ENST00000357068.11
ENST00000420436.5
ENST00000334029.6
ENST00000610940.4
proline dehydrogenase 1
chr12_+_80716906 0.22 ENST00000228644.4
myogenic factor 5
chr1_+_151762899 0.22 ENST00000635322.1
ENST00000321531.10
ornithine decarboxylase antizyme 3
chr4_-_88284590 0.22 ENST00000510548.6
protein phosphatase, Mg2+/Mn2+ dependent 1K
chr4_-_88284616 0.22 ENST00000508256.5
protein phosphatase, Mg2+/Mn2+ dependent 1K
chr14_-_22957100 0.22 ENST00000555367.5
HAUS augmin like complex subunit 4
chr8_+_22567038 0.22 ENST00000523348.1
sorbin and SH3 domain containing 3
chr16_-_29899532 0.22 ENST00000308713.9
ENST00000617533.5
seizure related 6 homolog like 2
chr12_-_6124662 0.22 ENST00000261405.10
von Willebrand factor
chr10_-_13707536 0.22 ENST00000632570.1
ENST00000477221.2
FERM domain containing 4A
chr17_-_81683782 0.22 ENST00000622299.5
ADP ribosylation factor like GTPase 16
chr14_-_22957128 0.22 ENST00000342454.12
ENST00000555986.5
ENST00000554516.5
ENST00000347758.6
ENST00000206474.11
ENST00000555040.5
HAUS augmin like complex subunit 4
chr20_+_58907981 0.22 ENST00000656419.1
GNAS complex locus
chr10_-_48652493 0.22 ENST00000435790.6
Rho GTPase activating protein 22
chr11_+_65181194 0.21 ENST00000533820.5
calpain 1
chr17_+_8002610 0.21 ENST00000254854.5
guanylate cyclase 2D, retinal
chr5_+_127649018 0.21 ENST00000379445.7
cortexin 3
chr12_-_10453330 0.21 ENST00000347831.9
ENST00000359151.8
killer cell lectin like receptor C1
chr8_-_130386864 0.21 ENST00000521426.5
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr7_+_124476371 0.21 ENST00000473520.1
SSU72 pseudogene 8
chr1_-_27672178 0.21 ENST00000339145.8
ENST00000361157.11
ENST00000362020.4
ENST00000679644.1
interferon alpha inducible protein 6
chr16_+_11965234 0.21 ENST00000562385.1
TNF receptor superfamily member 17
chr9_-_37025733 0.21 ENST00000651550.1
paired box 5
chr8_-_134510182 0.21 ENST00000521673.5
zinc finger and AT-hook domain containing
chr9_+_122371036 0.21 ENST00000619306.5
ENST00000426608.6
ENST00000223423.8
prostaglandin-endoperoxide synthase 1
chr4_+_69931066 0.20 ENST00000246891.9
casein alpha s1
chr4_-_142305826 0.20 ENST00000514525.1
inositol polyphosphate-4-phosphatase type II B
chr15_+_62561361 0.20 ENST00000561311.5
talin 2
chr16_+_24729692 0.20 ENST00000315183.11
trinucleotide repeat containing adaptor 6A

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.8 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.3 0.8 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.2 1.2 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.2 0.7 GO:0002668 negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017)
0.2 4.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.2 0.7 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.1 0.4 GO:2000118 dentinogenesis(GO:0097187) regulation of sodium-dependent phosphate transport(GO:2000118)
0.1 0.4 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.1 0.6 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.1 0.3 GO:0035470 positive regulation of vascular wound healing(GO:0035470)
0.1 0.5 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.1 0.1 GO:0003257 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.1 0.3 GO:0060279 positive regulation of ovulation(GO:0060279)
0.1 0.3 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.3 GO:0015847 putrescine transport(GO:0015847)
0.1 0.4 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 1.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.5 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.8 GO:0006689 ganglioside catabolic process(GO:0006689)
0.1 0.7 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 0.2 GO:0018874 benzoate metabolic process(GO:0018874)
0.1 0.2 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 0.6 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.2 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.1 2.1 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.1 0.2 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.1 0.8 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.2 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.1 0.5 GO:0050957 equilibrioception(GO:0050957)
0.1 1.4 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.1 0.2 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.1 0.4 GO:0019236 response to pheromone(GO:0019236)
0.0 0.2 GO:0015855 canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.0 0.1 GO:0003162 atrioventricular node development(GO:0003162)
0.0 0.7 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.1 GO:0033025 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) mast cell proliferation(GO:0070662)
0.0 0.5 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.7 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.4 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.2 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.3 GO:0097680 maintenance of Golgi location(GO:0051684) double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0 0.2 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.1 GO:0099540 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.0 0.1 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.3 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:0097272 ammonia homeostasis(GO:0097272)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.2 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 1.5 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.9 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.1 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 0.1 GO:1990451 cellular stress response to acidic pH(GO:1990451)
0.0 0.1 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.0 0.1 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.4 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.6 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.2 GO:0048241 epinephrine transport(GO:0048241)
0.0 0.3 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.0 0.1 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.0 0.3 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.6 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.1 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.0 0.2 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.3 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.3 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.3 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.4 GO:0035878 nail development(GO:0035878)
0.0 0.3 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.1 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.4 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.4 GO:0032196 transposition(GO:0032196)
0.0 0.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 1.0 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.1 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.7 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.1 GO:0071626 mastication(GO:0071626) learned vocalization behavior(GO:0098583)
0.0 1.2 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.4 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.5 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.0 0.4 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.1 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.0 0.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.0 0.7 GO:0006706 steroid catabolic process(GO:0006706)
0.0 0.1 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.3 GO:0009642 response to light intensity(GO:0009642)
0.0 0.2 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.1 GO:0061552 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.0 0.9 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.3 GO:0061314 Notch signaling involved in heart development(GO:0061314)
0.0 0.6 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.3 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.3 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.0 GO:0044771 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.3 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.1 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.0 0.4 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.4 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.1 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.0 0.2 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.0 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.0 0.2 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.2 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.1 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.1 GO:1903961 positive regulation of anion transmembrane transport(GO:1903961)
0.0 0.1 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.2 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.2 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.9 GO:0044364 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.0 0.4 GO:0006907 pinocytosis(GO:0006907)
0.0 0.1 GO:0002934 desmosome organization(GO:0002934)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.2 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.1 GO:0060770 epithelial cell proliferation involved in prostate gland development(GO:0060767) regulation of epithelial cell proliferation involved in prostate gland development(GO:0060768) negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.1 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.0 0.1 GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0 0.1 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 1.0 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.2 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.3 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.2 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.1 GO:0003350 pulmonary myocardium development(GO:0003350)
0.0 0.2 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.1 GO:0038129 ERBB3 signaling pathway(GO:0038129)
0.0 0.1 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.1 GO:2000504 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.2 GO:0018026 histone H3-K36 methylation(GO:0010452) peptidyl-lysine monomethylation(GO:0018026)
0.0 0.0 GO:0043396 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
0.0 0.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.4 GO:0048305 immunoglobulin secretion(GO:0048305)
0.0 0.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.2 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.6 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.0 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.0 GO:0048058 compound eye corneal lens development(GO:0048058)
0.0 0.5 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0 0.0 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.0 0.4 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.2 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.0 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.2 0.8 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.2 3.8 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 1.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.3 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.9 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.4 GO:0014802 terminal cisterna(GO:0014802)
0.1 0.7 GO:0070652 HAUS complex(GO:0070652)
0.1 0.3 GO:0071942 XPC complex(GO:0071942)
0.1 0.8 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.3 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.6 GO:0031209 SCAR complex(GO:0031209)
0.0 0.5 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 1.1 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 1.1 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.0 0.4 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.3 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.3 GO:0030897 HOPS complex(GO:0030897)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.1 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 2.3 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 3.9 GO:0043209 myelin sheath(GO:0043209)
0.0 2.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.0 GO:0019031 viral envelope(GO:0019031) viral membrane(GO:0036338)
0.0 0.0 GO:0005592 collagen type XI trimer(GO:0005592)
0.0 0.4 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.0 GO:0060342 photoreceptor inner segment membrane(GO:0060342)
0.0 0.1 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.6 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.6 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.3 0.8 GO:0032428 sphingolipid activator protein activity(GO:0030290) beta-N-acetylgalactosaminidase activity(GO:0032428)
0.2 0.6 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.2 0.7 GO:0070404 NADH binding(GO:0070404)
0.2 1.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.2 0.7 GO:0004773 steryl-sulfatase activity(GO:0004773)
0.2 0.8 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1 0.7 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.1 0.4 GO:0016608 growth hormone-releasing hormone activity(GO:0016608)
0.1 0.5 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 0.3 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.1 0.3 GO:0017129 triglyceride binding(GO:0017129)
0.1 0.3 GO:0015489 polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
0.1 0.4 GO:0050211 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211)
0.1 0.4 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 0.5 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 0.4 GO:0004803 transposase activity(GO:0004803)
0.1 0.3 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 0.4 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.8 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.2 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.1 0.3 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 1.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 0.4 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.4 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.2 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.1 2.5 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 0.2 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.1 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.0 0.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.4 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.2 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.1 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.0 0.3 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.0 0.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0000994 RNA polymerase III core binding(GO:0000994)
0.0 0.3 GO:0034711 inhibin binding(GO:0034711)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 2.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.4 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.5 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.4 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.1 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.0 0.0 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.1 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0 0.6 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.5 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.6 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 1.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.3 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 4.1 GO:0051015 actin filament binding(GO:0051015)
0.0 0.7 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.1 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.1 GO:0019862 IgA binding(GO:0019862)
0.0 0.1 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.0 GO:0005042 netrin receptor activity(GO:0005042)
0.0 1.6 GO:0051117 ATPase binding(GO:0051117)
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.0 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.3 GO:0005549 odorant binding(GO:0005549)
0.0 0.2 GO:0048185 activin binding(GO:0048185)
0.0 0.0 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.0 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 4.2 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.8 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 5.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.7 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.7 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.2 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.4 PID CONE PATHWAY Visual signal transduction: Cones

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 1.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 1.2 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.7 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.4 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 1.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.6 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 1.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.3 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.9 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 3.2 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 1.0 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 1.5 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.5 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.1 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.4 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis