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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for EOMES

Z-value: 0.87

Motif logo

Transcription factors associated with EOMES

Gene Symbol Gene ID Gene Info
ENSG00000163508.13 EOMES

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EOMEShg38_v1_chr3_-_27722699_277227170.232.2e-01Click!

Activity profile of EOMES motif

Sorted Z-values of EOMES motif

Network of associatons between targets according to the STRING database.

First level regulatory network of EOMES

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr6_+_116616467 5.03 ENST00000229554.10
ENST00000368581.8
ENST00000368580.4
radial spoke head component 4A
chr16_-_66925526 3.89 ENST00000299759.11
ENST00000420652.5
RRAD, Ras related glycolysis inhibitor and calcium channel regulator
chr19_-_55166565 3.84 ENST00000526003.5
ENST00000534170.5
ENST00000524407.7
dynein axonemal assembly factor 3
chr15_-_56465130 3.65 ENST00000260453.4
meiosis specific nuclear structural 1
chr4_-_16084002 3.56 ENST00000447510.7
prominin 1
chr4_-_16083714 3.01 ENST00000508167.5
prominin 1
chr4_-_16083695 3.00 ENST00000510224.5
prominin 1
chr22_-_50532077 2.94 ENST00000428989.3
ENST00000403326.5
outer dense fiber of sperm tails 3B
chr17_+_9576627 2.74 ENST00000396219.7
ENST00000352665.10
cilia and flagella associated protein 52
chr20_-_40689228 2.62 ENST00000373313.3
MAF bZIP transcription factor B
chr22_-_50532137 2.45 ENST00000405135.5
ENST00000401779.5
ENST00000682240.1
outer dense fiber of sperm tails 3B
chr3_-_114056481 2.39 ENST00000295878.8
ENST00000483766.1
ENST00000491000.5
coiled-coil domain containing 191
chr2_+_98087160 2.31 ENST00000477737.6
von Willebrand factor A domain containing 3B
chr7_+_6754109 2.28 ENST00000403107.5
ENST00000404077.5
ENST00000435395.5
ENST00000418406.1
radial spoke head 10 homolog B2
chr7_-_5970632 2.18 ENST00000455618.2
ENST00000405415.5
ENST00000404406.5
ENST00000542644.1
radial spoke head 10 homolog B
chr1_-_206921987 2.14 ENST00000530505.1
ENST00000442471.4
Fc fragment of IgM receptor
chr5_+_157266079 2.14 ENST00000616178.4
ENST00000522463.5
ENST00000435847.6
ENST00000620254.5
ENST00000521420.5
ENST00000617629.4
cytoplasmic FMR1 interacting protein 2
chr1_-_206921867 2.14 ENST00000628511.2
ENST00000367091.8
Fc fragment of IgM receptor
chr17_-_19362732 2.07 ENST00000395616.7
B9 domain containing 1
chr3_-_108222362 1.95 ENST00000492106.1
intraflagellar transport 57
chr5_+_76403266 1.89 ENST00000274364.11
IQ motif containing GTPase activating protein 2
chr7_+_90245167 1.86 ENST00000389297.8
cilia and flagella associated protein 69
chr7_+_90245207 1.71 ENST00000497910.5
cilia and flagella associated protein 69
chr14_-_53954470 1.66 ENST00000417573.5
bone morphogenetic protein 4
chr7_+_102464921 1.56 ENST00000463739.5
ENST00000292616.10
ENST00000626402.1
leucine rich repeats and WD repeat domain containing 1
chr12_-_94459854 1.50 ENST00000397809.10
centrosomal protein 83
chr11_-_8593940 1.47 ENST00000315204.5
ENST00000396672.5
ENST00000431279.6
ENST00000418597.5
serine/threonine kinase 33
chr14_+_96392095 1.45 ENST00000267584.9
ENST00000555570.1
adenylate kinase 7
chr8_+_98064522 1.37 ENST00000545282.1
glutamate rich 5
chr16_-_2329687 1.35 ENST00000567910.1
ATP binding cassette subfamily A member 3
chr9_+_68705230 1.29 ENST00000265382.8
phosphatidylinositol-4-phosphate 5-kinase type 1 beta
chr22_-_50532489 1.29 ENST00000329363.9
ENST00000437588.2
outer dense fiber of sperm tails 3B
chr17_-_19362669 1.28 ENST00000268841.10
ENST00000663089.1
ENST00000675510.1
ENST00000647252.1
ENST00000477683.5
ENST00000575478.7
ENST00000261499.10
B9 domain containing 1
chr11_-_8594181 1.28 ENST00000358872.7
ENST00000454443.2
serine/threonine kinase 33
chr2_-_228181612 1.28 ENST00000344657.5
SPHK1 interactor, AKAP domain containing
chr3_-_128123765 1.26 ENST00000322623.10
RuvB like AAA ATPase 1
chr2_-_228181669 1.24 ENST00000392056.8
SPHK1 interactor, AKAP domain containing
chr7_+_107044689 1.23 ENST00000265717.5
protein kinase cAMP-dependent type II regulatory subunit beta
chr1_+_3698027 1.23 ENST00000378290.4
tumor protein p73
chr1_-_167937037 1.23 ENST00000271373.9
mitochondrial pyruvate carrier 2
chr8_+_80485641 1.17 ENST00000430430.5
zinc finger and BTB domain containing 10
chr11_-_106022209 1.16 ENST00000301919.9
ENST00000534458.1
ENST00000530108.1
ENST00000530788.1
Myb/SANT DNA binding domain containing 4 with coiled-coils
chr8_+_98064559 1.15 ENST00000318528.8
glutamate rich 5
chrY_+_12904860 1.09 ENST00000336079.8
DEAD-box helicase 3 Y-linked
chr11_+_65711991 1.09 ENST00000377046.7
ENST00000352980.8
lysine acetyltransferase 5
chr11_+_65712231 1.09 ENST00000530446.5
ENST00000534104.5
ENST00000341318.9
ENST00000530605.5
ENST00000528198.5
ENST00000531880.1
ENST00000534650.5
lysine acetyltransferase 5
chr17_+_70104848 1.02 ENST00000392670.5
potassium inwardly rectifying channel subfamily J member 16
chr7_+_91940970 1.01 ENST00000359028.7
A-kinase anchoring protein 9
chr3_+_125969152 0.98 ENST00000251776.8
ENST00000504401.1
rhophilin associated tail protein 1B
chr5_+_56909586 0.97 ENST00000285947.5
SET domain containing 9
chr7_-_138798188 0.95 ENST00000310018.7
ATPase H+ transporting V0 subunit a4
chr4_+_54657918 0.92 ENST00000412167.6
ENST00000288135.6
KIT proto-oncogene, receptor tyrosine kinase
chr5_+_149730260 0.91 ENST00000360453.8
ENST00000394320.7
ENST00000309241.10
PPARG coactivator 1 beta
chr17_-_35448742 0.91 ENST00000534689.5
ENST00000532210.5
ENST00000285013.11
ENST00000526861.5
ENST00000531588.1
schlafen family member 13
chr6_-_139291987 0.89 ENST00000358430.8
taxilin beta
chr1_-_115089414 0.87 ENST00000433172.3
ENST00000369515.6
ENST00000369516.7
tetraspanin 2
chr22_-_42090743 0.86 ENST00000498737.8
ENST00000617763.1
NADH:ubiquinone oxidoreductase subunit A6
chr13_+_24680407 0.84 ENST00000381946.5
ENST00000218548.10
ATPase H+/K+ transporting non-gastric alpha2 subunit
chr7_+_116953514 0.83 ENST00000446490.5
suppression of tumorigenicity 7
chr16_-_4847265 0.83 ENST00000591451.5
ENST00000436648.9
ENST00000321919.14
ENST00000588297.5
glyoxylate reductase 1 homolog
chr9_+_97307645 0.83 ENST00000529487.3
coiled-coil domain containing 180
chr20_-_63831214 0.82 ENST00000302995.2
ENST00000245663.9
zinc finger and BTB domain containing 46
chr10_-_60141004 0.82 ENST00000355288.6
ankyrin 3
chr1_-_108661375 0.82 ENST00000370032.9
HEN methyltransferase 1
chr15_-_52678560 0.81 ENST00000562351.2
ENST00000261844.11
ENST00000399202.8
ENST00000562135.5
family with sequence similarity 214 member A
chr7_-_138798104 0.81 ENST00000353492.4
ATPase H+ transporting V0 subunit a4
chr1_+_14929734 0.80 ENST00000376028.8
ENST00000400798.6
kazrin, periplakin interacting protein
chr8_+_143018479 0.80 ENST00000429120.6
ENST00000521699.5
ENST00000520531.5
ENST00000520466.5
ENST00000521003.5
ENST00000522528.5
ENST00000292494.11
ENST00000522971.5
ENST00000519611.5
ENST00000521182.5
ENST00000519546.5
ENST00000523847.5
ENST00000522024.1
lymphocyte antigen 6 family member E
chr6_-_131628060 0.78 ENST00000539158.1
ENST00000368058.5
mediator complex subunit 23
chr17_+_60677822 0.78 ENST00000407086.8
ENST00000589222.5
ENST00000626960.2
ENST00000390652.9
BCAS3 microtubule associated cell migration factor
chr1_-_108661055 0.78 ENST00000370031.5
ENST00000651461.1
ENST00000402983.5
ENST00000420055.1
HEN methyltransferase 1
chrX_+_51406947 0.77 ENST00000342995.4
EZH inhibitory protein
chr12_-_89524734 0.75 ENST00000529983.3
polypeptide N-acetylgalactosaminyltransferase 4
chr17_-_19362542 0.75 ENST00000440841.1
ENST00000671102.1
ENST00000461069.6
B9 domain containing 1
chr8_+_17027230 0.74 ENST00000318063.10
mitochondrial calcium uptake family member 3
chr7_+_138797952 0.74 ENST00000397602.7
ENST00000442682.7
ENST00000458494.1
ENST00000413208.1
transmembrane protein 213
chr5_-_801145 0.73 ENST00000424784.3
zinc finger DHHC-type containing 11
chr7_+_91940836 0.73 ENST00000680534.1
ENST00000680513.1
ENST00000680072.1
A-kinase anchoring protein 9
chr17_-_43907467 0.72 ENST00000520406.5
ENST00000518478.1
ENST00000522172.5
ENST00000461854.5
ENST00000521178.5
ENST00000269095.9
ENST00000520305.5
ENST00000523501.5
ENST00000520241.5
membrane palmitoylated protein 2
chr11_-_45907265 0.72 ENST00000449465.2
chromosome 11 open reading frame 94
chr11_+_1919694 0.70 ENST00000278317.11
ENST00000453458.5
ENST00000381557.6
ENST00000381579.7
ENST00000381589.7
ENST00000381563.8
ENST00000344578.8
ENST00000381558.6
troponin T3, fast skeletal type
chr8_+_95133746 0.70 ENST00000315367.4
pleckstrin homology and FYVE domain containing 2
chrX_+_10158448 0.70 ENST00000380829.5
ENST00000421085.7
ENST00000674669.1
ENST00000454850.1
chloride voltage-gated channel 4
chr18_+_51030100 0.69 ENST00000589076.5
ENST00000590061.1
ENST00000342988.8
SMAD family member 4
chr6_-_3157536 0.68 ENST00000333628.4
tubulin beta 2A class IIa
chr17_-_10198592 0.67 ENST00000432992.7
growth arrest specific 7
chr11_+_537517 0.66 ENST00000270115.8
leucine rich repeat containing 56
chr19_+_48993525 0.66 ENST00000601968.5
ENST00000596837.5
RuvB like AAA ATPase 2
chr2_-_148020754 0.65 ENST00000440042.1
ENST00000536575.5
origin recognition complex subunit 4
chr15_-_93073706 0.65 ENST00000425933.6
repulsive guidance molecule BMP co-receptor a
chr4_-_75630473 0.65 ENST00000307465.9
cyclin dependent kinase like 2
chrX_+_35798791 0.65 ENST00000399985.1
MAGE family member B16
chr17_-_64497025 0.64 ENST00000539111.7
DNA polymerase gamma 2, accessory subunit
chr14_-_91836440 0.64 ENST00000340892.9
ENST00000360594.9
tandem C2 domains, nuclear
chr22_-_42070778 0.63 ENST00000396398.8
ENST00000403363.5
ENST00000402937.1
alpha-N-acetylgalactosaminidase
chr22_-_37149900 0.63 ENST00000216223.10
interleukin 2 receptor subunit beta
chr2_-_218010202 0.63 ENST00000646520.1
tensin 1
chr20_-_62937936 0.63 ENST00000266070.8
ENST00000370371.8
death inducer-obliterator 1
chr5_+_139648914 0.62 ENST00000502336.5
ENST00000520967.1
ENST00000511048.1
CXXC finger protein 5
chr11_-_8594140 0.62 ENST00000534493.5
ENST00000422559.6
serine/threonine kinase 33
chr17_-_58219227 0.61 ENST00000581180.2
ENST00000313863.11
ENST00000393119.7
ENST00000678463.1
ENST00000676787.1
ENST00000580127.6
ENST00000585134.2
ENST00000581761.6
MKS transition zone complex subunit 1
chr9_+_976648 0.61 ENST00000190165.3
doublesex and mab-3 related transcription factor 3
chr10_-_13300051 0.60 ENST00000479604.1
ENST00000263038.9
phytanoyl-CoA 2-hydroxylase
chr11_+_120240135 0.60 ENST00000543440.7
POU class 2 homeobox 3
chr10_-_50623897 0.60 ENST00000361781.7
ENST00000429490.5
ENST00000619438.4
sphingomyelin synthase 1
chr2_-_148020689 0.59 ENST00000457954.5
ENST00000392857.10
ENST00000540442.5
ENST00000535373.5
origin recognition complex subunit 4
chr15_-_43330537 0.59 ENST00000305641.7
ENST00000567039.1
leucine carboxyl methyltransferase 2
chr3_-_123992046 0.58 ENST00000467907.5
ENST00000459660.5
ENST00000495093.1
ENST00000460743.5
ENST00000405845.7
ENST00000484329.1
ENST00000479867.1
ENST00000496145.5
rhophilin associated tail protein 1
chrY_+_2935281 0.58 ENST00000383052.5
ENST00000155093.8
ENST00000625061.3
ENST00000443793.1
ENST00000449237.4
zinc finger protein Y-linked
chr12_+_130953898 0.57 ENST00000261654.10
adhesion G protein-coupled receptor D1
chr6_+_1312090 0.57 ENST00000296839.5
forkhead box Q1
chr17_+_69502397 0.57 ENST00000613873.4
ENST00000589647.5
mitogen-activated protein kinase kinase 6
chr11_+_8081202 0.56 ENST00000299506.3
TUB bipartite transcription factor
chr2_+_45651650 0.56 ENST00000306156.8
protein kinase C epsilon
chr16_+_31117656 0.56 ENST00000219797.9
ENST00000448516.6
lysine acetyltransferase 8
chr22_-_23751080 0.56 ENST00000341976.5
zinc finger protein 70
chr3_-_43105939 0.56 ENST00000441964.1
protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)
chr7_-_100428657 0.56 ENST00000360951.8
ENST00000398027.6
ENST00000684423.1
ENST00000472716.1
zinc finger CW-type and PWWP domain containing 1
chr9_-_127874964 0.54 ENST00000373156.5
adenylate kinase 1
chr22_+_46674593 0.54 ENST00000408031.1
GRAM domain containing 4
chr17_-_61928005 0.54 ENST00000444766.7
integrator complex subunit 2
chr17_-_17206264 0.53 ENST00000321560.4
phospholipase D family member 6
chr1_+_246566422 0.53 ENST00000366513.9
ENST00000366512.7
consortin, connexin sorting protein
chr8_-_89984231 0.53 ENST00000517337.1
ENST00000409330.5
nibrin
chr14_-_21511290 0.53 ENST00000298717.9
methyltransferase like 3
chr17_+_70169516 0.53 ENST00000243457.4
potassium inwardly rectifying channel subfamily J member 2
chr7_-_36985060 0.52 ENST00000396040.6
engulfment and cell motility 1
chr15_+_83447411 0.52 ENST00000324537.5
SH3 domain containing GRB2 like 3, endophilin A3
chr10_+_22321056 0.52 ENST00000376663.8
BMI1 proto-oncogene, polycomb ring finger
chr17_-_61927968 0.51 ENST00000646954.1
ENST00000251334.7
ENST00000647009.1
integrator complex subunit 2
chr8_-_78805306 0.51 ENST00000639719.1
ENST00000263851.9
interleukin 7
chr5_+_139648338 0.51 ENST00000302517.8
CXXC finger protein 5
chr1_-_43285559 0.51 ENST00000523677.6
chromosome 1 open reading frame 210
chr19_+_37594830 0.50 ENST00000589117.5
zinc finger protein 540
chr1_+_26111798 0.50 ENST00000374269.2
ENST00000374271.8
PDLIM1 interacting kinase 1 like
chr12_-_42483604 0.49 ENST00000640132.1
prickle planar cell polarity protein 1
chr8_-_78805515 0.49 ENST00000379113.6
ENST00000541183.2
interleukin 7
chr3_-_43106057 0.49 ENST00000344697.3
protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)
chr8_+_95133940 0.48 ENST00000519516.1
pleckstrin homology and FYVE domain containing 2
chr17_-_7329266 0.48 ENST00000571887.5
ENST00000315614.11
ENST00000399464.7
ENST00000570460.5
neuralized E3 ubiquitin protein ligase 4
chr16_+_4846652 0.47 ENST00000592120.5
ubinuclein 1
chr21_+_37073213 0.47 ENST00000418766.5
ENST00000450533.5
ENST00000438055.5
ENST00000355666.5
ENST00000540756.5
ENST00000399010.5
tetratricopeptide repeat domain 3
chr15_-_34969688 0.47 ENST00000156471.10
aquarius intron-binding spliceosomal factor
chr6_-_131628165 0.47 ENST00000368053.8
ENST00000354577.8
ENST00000368060.7
ENST00000368068.8
mediator complex subunit 23
chr14_+_75661186 0.47 ENST00000556977.5
ENST00000298832.14
ENST00000557636.5
ENST00000286650.9
tubulin tyrosine ligase like 5
chr2_+_183124428 0.47 ENST00000295119.9
nucleoporin 35
chr17_+_7705193 0.46 ENST00000226091.3
ephrin B3
chr11_-_64284639 0.46 ENST00000394532.7
ENST00000394531.3
ENST00000309032.8
BCL2 associated agonist of cell death
chr1_-_203175783 0.46 ENST00000621380.1
ENST00000255416.9
myosin binding protein H
chr1_+_15247267 0.46 ENST00000358897.8
ENST00000433640.7
forkhead associated phosphopeptide binding domain 1
chr8_-_89984609 0.46 ENST00000519426.5
ENST00000265433.8
nibrin
chr6_+_148342759 0.46 ENST00000367467.8
SAM and SH3 domain containing 1
chr2_-_101151253 0.46 ENST00000376840.8
ENST00000409318.2
TBC1 domain family member 8
chr7_+_70596078 0.45 ENST00000644506.1
activator of transcription and developmental regulator AUTS2
chr12_-_42483958 0.45 ENST00000548696.6
ENST00000552240.6
prickle planar cell polarity protein 1
chr3_-_105869035 0.45 ENST00000447441.6
ENST00000403724.5
ENST00000405772.5
Cbl proto-oncogene B
chr16_+_66880503 0.45 ENST00000568869.1
ENST00000311765.4
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr4_-_75940964 0.45 ENST00000507956.5
ENST00000507187.2
ENST00000286733.9
N-acylethanolamine acid amidase
chr17_+_74431338 0.45 ENST00000342648.9
ENST00000652232.1
ENST00000481232.2
G protein-coupled receptor class C group 5 member C
chr9_+_2017383 0.45 ENST00000382194.6
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr13_+_112979306 0.45 ENST00000421756.5
MCF.2 cell line derived transforming sequence like
chr3_-_158732442 0.45 ENST00000479756.1
ENST00000237696.10
retinoic acid receptor responder 1
chr1_+_25272492 0.45 ENST00000454452.6
Rh blood group D antigen
chr8_+_117520696 0.44 ENST00000297347.7
mediator complex subunit 30
chr6_+_78867524 0.44 ENST00000369940.7
interleukin 1 receptor associated kinase 1 binding protein 1
chr14_-_103562257 0.44 ENST00000337322.4
ENST00000445922.2
BAG cochaperone 5
chr1_+_152663378 0.44 ENST00000368784.2
late cornified envelope 2D
chr6_+_167826848 0.44 ENST00000683244.1
ENST00000400825.8
afadin, adherens junction formation factor
chr12_+_31659187 0.44 ENST00000395763.7
electron transfer flavoprotein subunit beta lysine methyltransferase
chr1_+_160151597 0.44 ENST00000368081.9
ATPase Na+/K+ transporting subunit alpha 4
chr7_-_56116401 0.43 ENST00000329309.4
nuclear protein 2, transcriptional regulator
chr4_+_105895487 0.43 ENST00000506666.5
ENST00000503451.5
nephronectin
chr1_+_222618075 0.43 ENST00000344922.10
MIA SH3 domain ER export factor 3
chr11_+_63938971 0.42 ENST00000539656.5
ENST00000377793.9
N-alpha-acetyltransferase 40, NatD catalytic subunit
chr20_-_18057841 0.41 ENST00000278780.7
ovo like zinc finger 2
chr6_-_85643778 0.41 ENST00000676637.1
ENST00000678528.1
synaptotagmin binding cytoplasmic RNA interacting protein
chr12_-_121016345 0.41 ENST00000535367.1
ENST00000538296.5
ENST00000288757.7
ENST00000539736.5
ENST00000537817.5
chromosome 12 open reading frame 43
chr6_+_127266875 0.41 ENST00000610162.5
ENST00000608991.5
ENST00000610153.1
ring finger protein 146
chr5_-_123423337 0.41 ENST00000306467.10
ENST00000675330.1
ENST00000674684.1
centrosomal protein 120
chr11_+_73787853 0.40 ENST00000310614.12
ENST00000497094.6
ENST00000411840.6
ENST00000535277.5
ENST00000398483.7
ENST00000542303.5
mitochondrial ribosomal protein L48
chr18_+_32092610 0.40 ENST00000578107.5
ENST00000257190.9
ENST00000580499.1
ring finger protein 138
chr21_+_42513834 0.39 ENST00000352133.3
solute carrier family 37 member 1
chrX_+_70452286 0.39 ENST00000374355.7
discs large MAGUK scaffold protein 3
chr15_-_63833911 0.39 ENST00000560462.1
ENST00000558532.1
ENST00000561400.1
ENST00000443617.7
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
chr11_+_46277648 0.39 ENST00000621158.5
cAMP responsive element binding protein 3 like 1
chr10_-_102419693 0.39 ENST00000611678.4
pleckstrin and Sec7 domain containing
chr17_-_6640653 0.39 ENST00000571642.5
ENST00000361413.8
ENST00000572370.5
KIAA0753
chr5_+_80654644 0.39 ENST00000265081.7
mutS homolog 3
chr9_+_113221528 0.39 ENST00000374212.5
solute carrier family 31 member 1
chr1_-_36385872 0.39 ENST00000373129.7
serine/threonine kinase 40
chr2_-_98608452 0.39 ENST00000328709.8
ENST00000409997.1
cytochrome c oxidase assembly factor 5
chr4_-_7434895 0.38 ENST00000319098.7
prosaposin like 1
chr19_-_37594746 0.38 ENST00000593133.5
ENST00000590751.5
ENST00000358744.3
ENST00000328550.6
ENST00000451802.7
zinc finger protein 571
chr19_-_48364034 0.38 ENST00000435956.7
transmembrane protein 143
chr9_-_113221288 0.38 ENST00000446284.6
ENST00000414250.2
FKBP prolyl isomerase family member 15
chr19_-_36008752 0.38 ENST00000340477.9
ENST00000490730.1
ENST00000324444.9
spectrin repeat containing nuclear envelope family member 4
chr12_-_107093509 0.37 ENST00000008527.10
cryptochrome circadian regulator 1
chr3_-_52835011 0.37 ENST00000446157.3
musculoskeletal, embryonic nuclear protein 1
chr16_-_1981463 0.37 ENST00000356120.9
ENST00000354249.8
NADPH oxidase organizer 1
chr19_+_49453211 0.37 ENST00000540132.5
ENST00000293350.9
ENST00000455361.6
aldehyde dehydrogenase 16 family member A1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 9.6 GO:2000768 positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
1.0 3.9 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.7 2.6 GO:0035284 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.6 1.7 GO:0055020 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.3 2.1 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.3 0.9 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162) mast cell proliferation(GO:0070662)
0.3 2.3 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.2 1.2 GO:0006850 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.2 0.7 GO:0035262 gonad morphogenesis(GO:0035262)
0.2 0.8 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 0.6 GO:0072709 cellular response to sorbitol(GO:0072709)
0.2 0.9 GO:2000691 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.2 0.5 GO:0035498 carnosine metabolic process(GO:0035498)
0.2 0.5 GO:0030719 oocyte construction(GO:0007308) oocyte axis specification(GO:0007309) oocyte anterior/posterior axis specification(GO:0007314) pole plasm assembly(GO:0007315) maternal determination of anterior/posterior axis, embryo(GO:0008358) P granule organization(GO:0030719)
0.2 6.4 GO:0044458 motile cilium assembly(GO:0044458)
0.2 0.5 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.2 1.2 GO:0097338 response to clozapine(GO:0097338)
0.2 3.7 GO:0070986 left/right axis specification(GO:0070986)
0.2 0.5 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139) positive regulation of type B pancreatic cell development(GO:2000078)
0.1 0.6 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.1 0.9 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.1 1.0 GO:0031860 regulation of DNA-dependent DNA replication initiation(GO:0030174) telomeric 3' overhang formation(GO:0031860)
0.1 0.7 GO:0061083 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.1 1.8 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 1.3 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 1.7 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 0.5 GO:0033306 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
0.1 0.4 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1 0.4 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.1 1.3 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.4 GO:1904732 regulation of electron carrier activity(GO:1904732)
0.1 0.3 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1 0.4 GO:1903296 regulation of glutamate secretion, neurotransmission(GO:1903294) positive regulation of glutamate secretion, neurotransmission(GO:1903296)
0.1 0.3 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.1 5.5 GO:0035082 axoneme assembly(GO:0035082)
0.1 0.3 GO:0006532 fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
0.1 0.4 GO:1901143 insulin catabolic process(GO:1901143)
0.1 0.3 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.4 GO:2000847 negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.1 0.5 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.1 0.6 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.1 0.4 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.1 0.5 GO:1904688 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.1 0.4 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.1 1.6 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 0.8 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.1 0.3 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.1 2.6 GO:0000729 DNA double-strand break processing(GO:0000729)
0.1 0.6 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 0.5 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.1 1.9 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.1 1.0 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.1 0.4 GO:0060214 endocardium formation(GO:0060214)
0.1 0.3 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 0.6 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 0.3 GO:1904693 serotonergic neuron axon guidance(GO:0036515) midbrain morphogenesis(GO:1904693)
0.1 0.5 GO:0016198 axon choice point recognition(GO:0016198)
0.1 0.6 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 1.3 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.1 0.2 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 0.6 GO:0016139 glycoside catabolic process(GO:0016139)
0.1 0.6 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.1 2.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 0.5 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 0.2 GO:0031453 regulation of heterochromatin assembly(GO:0031445) positive regulation of heterochromatin assembly(GO:0031453)
0.1 0.4 GO:0015853 adenine transport(GO:0015853)
0.1 0.3 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 0.2 GO:0021784 postganglionic parasympathetic fiber development(GO:0021784)
0.1 1.2 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.1 0.3 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.1 0.1 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.1 0.3 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 4.1 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.1 0.2 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.1 1.9 GO:0071539 protein localization to centrosome(GO:0071539)
0.1 0.2 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.0 0.4 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.7 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 1.3 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.6 GO:0010578 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0 0.2 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.0 0.8 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 4.3 GO:0006968 cellular defense response(GO:0006968)
0.0 0.2 GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
0.0 0.5 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0 0.2 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.4 GO:0015677 copper ion import(GO:0015677)
0.0 0.2 GO:0061358 negative regulation of Wnt protein secretion(GO:0061358)
0.0 0.3 GO:0046103 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.0 0.3 GO:0040031 snRNA modification(GO:0040031)
0.0 0.7 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.2 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.3 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.6 GO:0070257 positive regulation of synaptic transmission, GABAergic(GO:0032230) positive regulation of mucus secretion(GO:0070257)
0.0 0.1 GO:0071033 nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
0.0 0.1 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0 0.4 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.2 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.6 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.2 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 2.1 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.5 GO:0007379 segment specification(GO:0007379)
0.0 0.6 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.6 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.2 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0 0.1 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.2 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.4 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.4 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 0.3 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.1 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.0 0.6 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 1.7 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.2 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.5 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.4 GO:0006983 ER overload response(GO:0006983)
0.0 0.9 GO:0046710 GDP metabolic process(GO:0046710)
0.0 0.6 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.0 0.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 1.0 GO:0002360 T cell lineage commitment(GO:0002360)
0.0 0.4 GO:0060263 regulation of respiratory burst(GO:0060263)
0.0 0.4 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.0 0.7 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.1 GO:0060157 urinary bladder development(GO:0060157)
0.0 0.2 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.6 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.5 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 1.0 GO:0010107 potassium ion import(GO:0010107)
0.0 0.2 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.0 0.4 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.6 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.4 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.8 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.0 0.2 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.2 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.4 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.1 GO:1904021 negative regulation of G-protein coupled receptor internalization(GO:1904021)
0.0 1.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.3 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.0 0.3 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.3 GO:0015871 choline transport(GO:0015871)
0.0 0.6 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.1 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.2 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.2 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.3 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.2 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.8 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.4 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.0 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.3 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.0 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.0 0.6 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.3 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.1 GO:1903027 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.0 0.2 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.3 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 0.0 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.0 0.1 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.1 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.7 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.0 0.6 GO:0097352 autophagosome maturation(GO:0097352)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 GO:0001534 radial spoke(GO:0001534)
0.5 1.4 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.4 9.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.4 1.7 GO:0044307 dendritic branch(GO:0044307)
0.4 1.6 GO:0031933 telomeric heterochromatin(GO:0031933)
0.3 2.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.2 0.6 GO:0000229 cytoplasmic chromosome(GO:0000229)
0.2 0.8 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.2 4.7 GO:0036038 MKS complex(GO:0036038)
0.2 1.8 GO:0097255 R2TP complex(GO:0097255)
0.2 1.8 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 2.1 GO:0044292 dendrite terminus(GO:0044292)
0.1 0.7 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 0.3 GO:0097543 ciliary inversin compartment(GO:0097543)
0.1 1.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.5 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 0.7 GO:0097452 GAIT complex(GO:0097452)
0.1 0.3 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 0.4 GO:0032302 MutSbeta complex(GO:0032302)
0.1 1.0 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.4 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.4 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 1.0 GO:0032039 integrator complex(GO:0032039)
0.1 0.6 GO:0072487 MSL complex(GO:0072487)
0.1 1.4 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 1.6 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.1 1.3 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 1.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0070701 mucus layer(GO:0070701)
0.0 0.4 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.3 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 0.8 GO:0000786 nucleosome(GO:0000786)
0.0 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.8 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 1.2 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.7 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.3 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 3.4 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.6 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 1.2 GO:0016592 mediator complex(GO:0016592)
0.0 0.4 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.9 GO:0042629 mast cell granule(GO:0042629)
0.0 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.4 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 1.2 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.5 GO:0032982 myosin filament(GO:0032982)
0.0 0.2 GO:0070552 BRISC complex(GO:0070552)
0.0 0.2 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 1.0 GO:0031941 filamentous actin(GO:0031941)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.4 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)
0.0 0.2 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.0 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753) proton-transporting ATP synthase complex(GO:0045259)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.4 GO:0042101 T cell receptor complex(GO:0042101)
0.0 2.0 GO:0031901 early endosome membrane(GO:0031901)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.1 GO:0008158 hedgehog receptor activity(GO:0008158)
0.4 1.3 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.3 1.0 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.3 0.8 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.3 1.9 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.3 0.8 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.2 1.4 GO:0004127 cytidylate kinase activity(GO:0004127)
0.2 0.6 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.2 0.8 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.2 0.5 GO:0046577 long-chain-alcohol oxidase activity(GO:0046577)
0.2 0.6 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.2 1.2 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.6 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 1.9 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.4 GO:0031626 beta-endorphin binding(GO:0031626)
0.1 1.7 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.7 GO:0030172 troponin C binding(GO:0030172)
0.1 9.9 GO:0042805 actinin binding(GO:0042805)
0.1 0.5 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.6 GO:0035276 ethanol binding(GO:0035276)
0.1 0.3 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 0.4 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.1 0.9 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 0.3 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 0.3 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 1.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 0.3 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.1 0.4 GO:0004146 dihydrofolate reductase activity(GO:0004146)
0.1 0.4 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.1 0.2 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.1 1.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.4 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 0.4 GO:0000406 double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.1 1.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.7 GO:0043199 sulfate binding(GO:0043199)
0.1 0.2 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.1 0.2 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.1 0.2 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 1.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 1.8 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 0.2 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.1 0.9 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 3.7 GO:0051018 protein kinase A binding(GO:0051018)
0.1 0.5 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.1 0.6 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1 0.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0071566 UFM1 activating enzyme activity(GO:0071566)
0.0 0.2 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 1.6 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.2 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0038047 beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.0 0.2 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.2 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.5 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.3 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.2 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.0 0.2 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 1.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:0015141 succinate transmembrane transporter activity(GO:0015141)
0.0 0.4 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.5 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.8 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.3 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.5 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.4 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.4 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0 0.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.3 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 2.2 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.7 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0031687 A2A adenosine receptor binding(GO:0031687)
0.0 0.1 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.7 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.6 GO:0035497 cAMP response element binding(GO:0035497)
0.0 1.1 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 0.4 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.2 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 1.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.0 0.5 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.4 GO:0009881 photoreceptor activity(GO:0009881)
0.0 0.4 GO:0043422 protein kinase B binding(GO:0043422)
0.0 1.7 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 0.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.4 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.2 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.7 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.0 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.0 1.3 GO:0016278 lysine N-methyltransferase activity(GO:0016278)
0.0 0.4 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.3 GO:0070513 death domain binding(GO:0070513)
0.0 0.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.3 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.3 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.0 GO:0097259 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.3 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.3 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.4 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.6 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.0 PID MYC PATHWAY C-MYC pathway
0.0 4.4 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.1 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.6 PID ALK2 PATHWAY ALK2 signaling events
0.0 2.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.2 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.2 PID BMP PATHWAY BMP receptor signaling
0.0 0.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.0 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.8 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.9 PID E2F PATHWAY E2F transcription factor network
0.0 0.6 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.7 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.5 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.6 PID P53 REGULATION PATHWAY p53 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1 1.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 1.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 1.8 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 2.0 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 1.0 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.2 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.9 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.6 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 1.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 1.1 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 1.9 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.4 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.5 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.6 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.9 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.4 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 1.8 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.4 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.6 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.3 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.6 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.6 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.4 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)