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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)
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Results for EP300
Z-value: 0.87
Motif logo
Transcription factors associated with EP300
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
EP300
|
ENSG00000100393.14 | EP300 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| EP300 | hg38_v1_chr22_+_41092869_41093005, hg38_v1_chr22_+_41092585_41092633 | -0.27 | 1.5e-01 | Click! |
Activity profile of EP300 motif
Sorted Z-values of EP300 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of EP300
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 6.2 | GO:0060356 | leucine import(GO:0060356) |
| 0.6 | 1.8 | GO:1905000 | regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000) |
| 0.5 | 1.0 | GO:0014724 | regulation of twitch skeletal muscle contraction(GO:0014724) |
| 0.5 | 1.6 | GO:2000537 | regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538) |
| 0.5 | 1.5 | GO:0035565 | regulation of pronephros size(GO:0035565) |
| 0.5 | 4.4 | GO:0060744 | thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744) epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) |
| 0.5 | 1.4 | GO:0005989 | lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989) |
| 0.4 | 3.7 | GO:0031444 | slow-twitch skeletal muscle fiber contraction(GO:0031444) |
| 0.4 | 4.5 | GO:0060753 | regulation of mast cell chemotaxis(GO:0060753) |
| 0.4 | 0.8 | GO:0051885 | positive regulation of anagen(GO:0051885) |
| 0.4 | 1.2 | GO:0035026 | leading edge cell differentiation(GO:0035026) |
| 0.3 | 3.6 | GO:0034625 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.3 | 0.7 | GO:0030807 | positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) |
| 0.3 | 1.3 | GO:0002541 | activation of plasma proteins involved in acute inflammatory response(GO:0002541) |
| 0.3 | 0.9 | GO:1903926 | signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926) |
| 0.3 | 2.2 | GO:0060066 | regulation of axon diameter(GO:0031133) oviduct development(GO:0060066) |
| 0.3 | 1.9 | GO:0033274 | response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829) |
| 0.3 | 2.0 | GO:0030421 | defecation(GO:0030421) |
| 0.3 | 7.1 | GO:0051639 | actin filament network formation(GO:0051639) |
| 0.3 | 1.1 | GO:0018106 | peptidyl-histidine phosphorylation(GO:0018106) |
| 0.3 | 0.8 | GO:1901876 | regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) |
| 0.2 | 0.7 | GO:0060762 | regulation of branching involved in mammary gland duct morphogenesis(GO:0060762) |
| 0.2 | 1.0 | GO:0046642 | negative regulation of alpha-beta T cell proliferation(GO:0046642) |
| 0.2 | 0.7 | GO:0097252 | oligodendrocyte apoptotic process(GO:0097252) |
| 0.2 | 0.7 | GO:0030221 | basophil differentiation(GO:0030221) |
| 0.2 | 1.3 | GO:0090238 | positive regulation of arachidonic acid secretion(GO:0090238) |
| 0.2 | 1.3 | GO:0008204 | ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204) |
| 0.2 | 0.6 | GO:0021503 | neural fold bending(GO:0021503) |
| 0.2 | 0.6 | GO:0002590 | regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641) |
| 0.2 | 2.1 | GO:0010756 | positive regulation of plasminogen activation(GO:0010756) |
| 0.2 | 0.8 | GO:1903436 | regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490) |
| 0.2 | 0.8 | GO:0009298 | GDP-mannose biosynthetic process(GO:0009298) |
| 0.2 | 4.4 | GO:0035589 | G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589) |
| 0.2 | 0.7 | GO:0003409 | optic cup structural organization(GO:0003409) |
| 0.2 | 2.4 | GO:0019532 | oxalate transport(GO:0019532) |
| 0.2 | 0.5 | GO:0098974 | postsynaptic actin cytoskeleton organization(GO:0098974) |
| 0.2 | 0.3 | GO:1900238 | positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591) |
| 0.2 | 1.6 | GO:0043696 | dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697) |
| 0.2 | 0.5 | GO:0007406 | negative regulation of neuroblast proliferation(GO:0007406) |
| 0.2 | 1.7 | GO:0007168 | receptor guanylyl cyclase signaling pathway(GO:0007168) |
| 0.2 | 0.6 | GO:1905150 | regulation of voltage-gated sodium channel activity(GO:1905150) |
| 0.2 | 0.8 | GO:0010751 | negative regulation of nitric oxide mediated signal transduction(GO:0010751) |
| 0.1 | 0.9 | GO:0071105 | response to interleukin-11(GO:0071105) |
| 0.1 | 0.6 | GO:0009631 | cold acclimation(GO:0009631) |
| 0.1 | 0.9 | GO:0071460 | cellular response to cell-matrix adhesion(GO:0071460) |
| 0.1 | 0.4 | GO:0050653 | chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653) |
| 0.1 | 1.9 | GO:0035092 | sperm chromatin condensation(GO:0035092) |
| 0.1 | 0.7 | GO:0010836 | negative regulation of protein ADP-ribosylation(GO:0010836) |
| 0.1 | 1.0 | GO:0060154 | cellular process regulating host cell cycle in response to virus(GO:0060154) |
| 0.1 | 0.4 | GO:0090237 | regulation of arachidonic acid secretion(GO:0090237) |
| 0.1 | 1.1 | GO:0070236 | negative regulation of activation-induced cell death of T cells(GO:0070236) |
| 0.1 | 1.0 | GO:1904431 | positive regulation of t-circle formation(GO:1904431) |
| 0.1 | 0.6 | GO:0014050 | negative regulation of glutamate secretion(GO:0014050) |
| 0.1 | 0.9 | GO:0019732 | antifungal humoral response(GO:0019732) |
| 0.1 | 0.3 | GO:1900111 | positive regulation of histone H3-K9 dimethylation(GO:1900111) |
| 0.1 | 1.7 | GO:0014051 | gamma-aminobutyric acid secretion(GO:0014051) |
| 0.1 | 0.3 | GO:0015917 | aminophospholipid transport(GO:0015917) |
| 0.1 | 0.5 | GO:0051673 | membrane disruption in other organism(GO:0051673) |
| 0.1 | 0.5 | GO:0048133 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
| 0.1 | 0.2 | GO:0000117 | regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117) |
| 0.1 | 1.1 | GO:2000535 | regulation of entry of bacterium into host cell(GO:2000535) |
| 0.1 | 0.4 | GO:2000255 | negative regulation of male germ cell proliferation(GO:2000255) |
| 0.1 | 0.8 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
| 0.1 | 0.2 | GO:0046601 | positive regulation of centriole replication(GO:0046601) |
| 0.1 | 0.3 | GO:0030997 | regulation of centriole-centriole cohesion(GO:0030997) |
| 0.1 | 0.5 | GO:2000286 | receptor internalization involved in canonical Wnt signaling pathway(GO:2000286) |
| 0.1 | 0.3 | GO:2001274 | immunoglobulin biosynthetic process(GO:0002378) negative regulation of glucose import in response to insulin stimulus(GO:2001274) |
| 0.1 | 7.6 | GO:0008088 | axo-dendritic transport(GO:0008088) |
| 0.1 | 2.8 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
| 0.1 | 0.4 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
| 0.1 | 0.3 | GO:0022007 | neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) |
| 0.1 | 0.7 | GO:0046604 | positive regulation of mitotic centrosome separation(GO:0046604) |
| 0.1 | 0.4 | GO:0033058 | directional locomotion(GO:0033058) |
| 0.1 | 0.3 | GO:0006550 | isoleucine catabolic process(GO:0006550) |
| 0.1 | 0.3 | GO:0046882 | negative regulation of B cell differentiation(GO:0045578) negative regulation of follicle-stimulating hormone secretion(GO:0046882) |
| 0.1 | 1.2 | GO:2000543 | positive regulation of gastrulation(GO:2000543) |
| 0.1 | 0.6 | GO:0010482 | epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482) |
| 0.1 | 0.9 | GO:0017182 | peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) |
| 0.1 | 0.5 | GO:0098706 | endosome localization(GO:0032439) ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706) negative regulation of vacuolar transport(GO:1903336) |
| 0.1 | 0.7 | GO:0009972 | cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087) |
| 0.1 | 0.3 | GO:1902723 | negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723) |
| 0.1 | 0.3 | GO:0060708 | spongiotrophoblast differentiation(GO:0060708) |
| 0.1 | 0.4 | GO:1901097 | negative regulation of autophagosome maturation(GO:1901097) |
| 0.1 | 0.7 | GO:0048170 | positive regulation of long-term neuronal synaptic plasticity(GO:0048170) |
| 0.1 | 0.3 | GO:0018199 | peptidyl-glutamine modification(GO:0018199) |
| 0.1 | 1.1 | GO:0006600 | creatine metabolic process(GO:0006600) |
| 0.1 | 1.2 | GO:0010991 | negative regulation of SMAD protein complex assembly(GO:0010991) |
| 0.1 | 0.2 | GO:0001827 | inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828) |
| 0.1 | 0.7 | GO:0045345 | positive regulation of MHC class I biosynthetic process(GO:0045345) |
| 0.1 | 0.3 | GO:0019082 | viral protein processing(GO:0019082) regulation of neurotrophin production(GO:0032899) negative regulation of neurotrophin production(GO:0032900) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472) |
| 0.1 | 0.2 | GO:0045556 | TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556) |
| 0.1 | 0.3 | GO:0006049 | UDP-N-acetylglucosamine catabolic process(GO:0006049) |
| 0.1 | 0.7 | GO:0000733 | DNA strand renaturation(GO:0000733) |
| 0.1 | 0.5 | GO:0034201 | response to oleic acid(GO:0034201) |
| 0.1 | 0.2 | GO:0036510 | trimming of terminal mannose on C branch(GO:0036510) |
| 0.1 | 1.5 | GO:0006491 | N-glycan processing(GO:0006491) |
| 0.1 | 1.0 | GO:0060907 | positive regulation of macrophage cytokine production(GO:0060907) |
| 0.1 | 0.2 | GO:0072023 | thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233) |
| 0.1 | 0.7 | GO:0098909 | regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909) |
| 0.1 | 0.4 | GO:0035965 | cardiolipin acyl-chain remodeling(GO:0035965) |
| 0.1 | 0.6 | GO:0032287 | peripheral nervous system myelin maintenance(GO:0032287) |
| 0.1 | 0.2 | GO:0072579 | molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579) |
| 0.1 | 1.6 | GO:0071243 | cellular response to arsenic-containing substance(GO:0071243) |
| 0.0 | 0.7 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
| 0.0 | 0.6 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.0 | 0.2 | GO:0045048 | protein insertion into ER membrane(GO:0045048) |
| 0.0 | 0.5 | GO:0031119 | tRNA pseudouridine synthesis(GO:0031119) |
| 0.0 | 0.4 | GO:0046070 | dGTP metabolic process(GO:0046070) |
| 0.0 | 0.1 | GO:0021526 | medial motor column neuron differentiation(GO:0021526) |
| 0.0 | 0.1 | GO:0046338 | phosphatidylethanolamine catabolic process(GO:0046338) |
| 0.0 | 0.5 | GO:0070120 | brainstem development(GO:0003360) ciliary neurotrophic factor-mediated signaling pathway(GO:0070120) |
| 0.0 | 1.2 | GO:0007213 | G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) |
| 0.0 | 0.3 | GO:0097338 | response to clozapine(GO:0097338) |
| 0.0 | 0.6 | GO:1903690 | negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
| 0.0 | 0.3 | GO:0021553 | olfactory nerve development(GO:0021553) |
| 0.0 | 0.9 | GO:0048742 | regulation of skeletal muscle fiber development(GO:0048742) |
| 0.0 | 0.0 | GO:1904933 | regulation of cell proliferation in midbrain(GO:1904933) |
| 0.0 | 0.4 | GO:1900122 | positive regulation of receptor binding(GO:1900122) |
| 0.0 | 1.0 | GO:0005513 | detection of calcium ion(GO:0005513) |
| 0.0 | 0.9 | GO:2000675 | negative regulation of type B pancreatic cell apoptotic process(GO:2000675) |
| 0.0 | 0.2 | GO:0051001 | negative regulation of nitric-oxide synthase activity(GO:0051001) |
| 0.0 | 0.2 | GO:0035627 | ceramide transport(GO:0035627) |
| 0.0 | 0.6 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 0.0 | 0.2 | GO:0038155 | interleukin-23-mediated signaling pathway(GO:0038155) |
| 0.0 | 0.6 | GO:0031274 | positive regulation of pseudopodium assembly(GO:0031274) |
| 0.0 | 0.6 | GO:0032808 | lacrimal gland development(GO:0032808) |
| 0.0 | 0.5 | GO:0060391 | positive regulation of SMAD protein import into nucleus(GO:0060391) |
| 0.0 | 0.1 | GO:0051795 | positive regulation of catagen(GO:0051795) |
| 0.0 | 0.3 | GO:0035469 | determination of pancreatic left/right asymmetry(GO:0035469) |
| 0.0 | 0.7 | GO:0043248 | proteasome assembly(GO:0043248) |
| 0.0 | 0.2 | GO:0070317 | negative regulation of G0 to G1 transition(GO:0070317) |
| 0.0 | 0.7 | GO:0006004 | fucose metabolic process(GO:0006004) |
| 0.0 | 0.4 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 0.0 | 0.1 | GO:0070172 | positive regulation of tooth mineralization(GO:0070172) |
| 0.0 | 0.9 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
| 0.0 | 1.9 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.0 | 0.6 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.0 | 0.6 | GO:0060856 | establishment of blood-brain barrier(GO:0060856) |
| 0.0 | 1.1 | GO:0097503 | sialylation(GO:0097503) |
| 0.0 | 0.8 | GO:0048745 | smooth muscle tissue development(GO:0048745) |
| 0.0 | 0.2 | GO:0006701 | progesterone biosynthetic process(GO:0006701) |
| 0.0 | 0.4 | GO:0016081 | synaptic vesicle docking(GO:0016081) |
| 0.0 | 0.1 | GO:0021759 | globus pallidus development(GO:0021759) |
| 0.0 | 0.3 | GO:0015747 | urate transport(GO:0015747) |
| 0.0 | 0.1 | GO:1900227 | positive regulation of NLRP3 inflammasome complex assembly(GO:1900227) |
| 0.0 | 1.2 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
| 0.0 | 0.5 | GO:0001778 | plasma membrane repair(GO:0001778) |
| 0.0 | 2.1 | GO:0043268 | positive regulation of potassium ion transport(GO:0043268) |
| 0.0 | 0.3 | GO:0060137 | maternal process involved in parturition(GO:0060137) |
| 0.0 | 0.1 | GO:0045629 | negative regulation of T-helper 2 cell differentiation(GO:0045629) |
| 0.0 | 0.7 | GO:2000369 | regulation of clathrin-mediated endocytosis(GO:2000369) |
| 0.0 | 0.4 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
| 0.0 | 0.1 | GO:0090234 | regulation of kinetochore assembly(GO:0090234) |
| 0.0 | 1.0 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
| 0.0 | 0.8 | GO:1900027 | regulation of ruffle assembly(GO:1900027) |
| 0.0 | 0.2 | GO:0060484 | lung-associated mesenchyme development(GO:0060484) |
| 0.0 | 0.2 | GO:0043654 | recognition of apoptotic cell(GO:0043654) |
| 0.0 | 0.9 | GO:0006359 | regulation of transcription from RNA polymerase III promoter(GO:0006359) |
| 0.0 | 0.0 | GO:2000619 | negative regulation of histone H4-K16 acetylation(GO:2000619) |
| 0.0 | 0.6 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.0 | 4.5 | GO:0007219 | Notch signaling pathway(GO:0007219) |
| 0.0 | 0.3 | GO:0006228 | UTP biosynthetic process(GO:0006228) |
| 0.0 | 0.6 | GO:0045332 | phospholipid translocation(GO:0045332) |
| 0.0 | 0.2 | GO:0035897 | proteolysis in other organism(GO:0035897) |
| 0.0 | 1.2 | GO:0001755 | neural crest cell migration(GO:0001755) |
| 0.0 | 0.6 | GO:0006833 | water transport(GO:0006833) |
| 0.0 | 0.1 | GO:0099538 | synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551) |
| 0.0 | 0.1 | GO:0048560 | establishment of anatomical structure orientation(GO:0048560) |
| 0.0 | 0.3 | GO:0090435 | protein localization to nuclear envelope(GO:0090435) |
| 0.0 | 0.8 | GO:0006692 | prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693) |
| 0.0 | 0.2 | GO:0021520 | spinal cord motor neuron cell fate specification(GO:0021520) |
| 0.0 | 0.1 | GO:0089700 | protein kinase D signaling(GO:0089700) |
| 0.0 | 0.2 | GO:0014718 | positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718) |
| 0.0 | 0.9 | GO:0044380 | protein localization to cytoskeleton(GO:0044380) |
| 0.0 | 0.3 | GO:0045793 | positive regulation of cell size(GO:0045793) |
| 0.0 | 0.5 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
| 0.0 | 0.6 | GO:0035428 | hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659) |
| 0.0 | 0.4 | GO:0006884 | cell volume homeostasis(GO:0006884) |
| 0.0 | 0.4 | GO:0035518 | histone H2A monoubiquitination(GO:0035518) |
| 0.0 | 0.2 | GO:0010457 | centriole-centriole cohesion(GO:0010457) positive regulation of nonmotile primary cilium assembly(GO:1902857) |
| 0.0 | 0.2 | GO:0015727 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) |
| 0.0 | 0.2 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
| 0.0 | 1.4 | GO:0006027 | glycosaminoglycan catabolic process(GO:0006027) |
| 0.0 | 1.1 | GO:0030834 | regulation of actin filament depolymerization(GO:0030834) |
| 0.0 | 0.4 | GO:0006294 | nucleotide-excision repair, preincision complex assembly(GO:0006294) |
| 0.0 | 0.2 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
| 0.0 | 0.7 | GO:0007080 | mitotic metaphase plate congression(GO:0007080) |
| 0.0 | 0.6 | GO:0000266 | mitochondrial fission(GO:0000266) |
| 0.0 | 0.1 | GO:0006335 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.0 | 0.0 | GO:0042989 | sequestering of actin monomers(GO:0042989) |
| 0.0 | 0.8 | GO:0007032 | endosome organization(GO:0007032) |
| 0.0 | 0.3 | GO:0006349 | regulation of gene expression by genetic imprinting(GO:0006349) |
| 0.0 | 0.1 | GO:0019464 | glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464) |
| 0.0 | 0.1 | GO:0051182 | coenzyme transport(GO:0051182) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 7.5 | GO:0035253 | ciliary rootlet(GO:0035253) |
| 0.4 | 1.8 | GO:0031523 | Myb complex(GO:0031523) |
| 0.3 | 7.1 | GO:0005916 | fascia adherens(GO:0005916) |
| 0.2 | 0.7 | GO:0010370 | perinucleolar chromocenter(GO:0010370) |
| 0.2 | 1.5 | GO:0032280 | symmetric synapse(GO:0032280) |
| 0.2 | 2.1 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.2 | 1.2 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 0.2 | 1.1 | GO:0035838 | growing cell tip(GO:0035838) |
| 0.2 | 3.9 | GO:0005861 | troponin complex(GO:0005861) |
| 0.1 | 0.6 | GO:0098984 | neuron to neuron synapse(GO:0098984) |
| 0.1 | 1.1 | GO:0032584 | growth cone membrane(GO:0032584) |
| 0.1 | 0.5 | GO:0097059 | CNTFR-CLCF1 complex(GO:0097059) |
| 0.1 | 1.2 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
| 0.1 | 2.6 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.1 | 0.3 | GO:0043512 | inhibin complex(GO:0043511) inhibin A complex(GO:0043512) |
| 0.1 | 0.3 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
| 0.1 | 0.6 | GO:1990357 | terminal web(GO:1990357) |
| 0.1 | 3.5 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.1 | 0.6 | GO:1990393 | 3M complex(GO:1990393) |
| 0.1 | 2.1 | GO:0097440 | apical dendrite(GO:0097440) |
| 0.1 | 0.6 | GO:0042721 | mitochondrial inner membrane protein insertion complex(GO:0042721) |
| 0.1 | 0.7 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
| 0.1 | 1.0 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.1 | 1.3 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.1 | 0.6 | GO:0000796 | condensin complex(GO:0000796) |
| 0.1 | 1.4 | GO:0005845 | mRNA cap binding complex(GO:0005845) |
| 0.1 | 0.6 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
| 0.1 | 0.6 | GO:0005879 | axonemal microtubule(GO:0005879) |
| 0.1 | 0.7 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
| 0.1 | 0.5 | GO:0098559 | cytoplasmic side of early endosome membrane(GO:0098559) |
| 0.1 | 0.3 | GO:0019815 | B cell receptor complex(GO:0019815) |
| 0.1 | 0.5 | GO:0097443 | sorting endosome(GO:0097443) |
| 0.0 | 0.4 | GO:0032585 | multivesicular body membrane(GO:0032585) |
| 0.0 | 0.8 | GO:0070938 | contractile ring(GO:0070938) |
| 0.0 | 1.1 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
| 0.0 | 0.4 | GO:0000110 | nucleotide-excision repair factor 1 complex(GO:0000110) |
| 0.0 | 1.3 | GO:0031233 | intrinsic component of external side of plasma membrane(GO:0031233) |
| 0.0 | 0.5 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.0 | 0.6 | GO:0035749 | myelin sheath adaxonal region(GO:0035749) |
| 0.0 | 4.6 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
| 0.0 | 0.5 | GO:0097433 | dense body(GO:0097433) |
| 0.0 | 0.3 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.0 | 0.6 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.0 | 0.2 | GO:0072536 | interleukin-23 receptor complex(GO:0072536) |
| 0.0 | 3.4 | GO:1904724 | tertiary granule lumen(GO:1904724) |
| 0.0 | 1.2 | GO:0097381 | photoreceptor disc membrane(GO:0097381) |
| 0.0 | 0.2 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
| 0.0 | 0.6 | GO:0045180 | basal cortex(GO:0045180) |
| 0.0 | 1.0 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 0.0 | 0.5 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.0 | 4.4 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.0 | 6.2 | GO:0048770 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.0 | 2.7 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
| 0.0 | 0.7 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.0 | 0.8 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.0 | 0.3 | GO:0019774 | proteasome core complex, beta-subunit complex(GO:0019774) |
| 0.0 | 1.2 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.0 | 0.2 | GO:1990745 | EARP complex(GO:1990745) |
| 0.0 | 1.6 | GO:0000502 | proteasome complex(GO:0000502) |
| 0.0 | 2.1 | GO:0008021 | synaptic vesicle(GO:0008021) |
| 0.0 | 3.7 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.0 | 0.5 | GO:0005685 | U1 snRNP(GO:0005685) |
| 0.0 | 0.3 | GO:0008091 | spectrin(GO:0008091) |
| 0.0 | 1.0 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.0 | 0.1 | GO:0005854 | nascent polypeptide-associated complex(GO:0005854) |
| 0.0 | 6.0 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.0 | 3.3 | GO:0030658 | transport vesicle membrane(GO:0030658) |
| 0.0 | 0.3 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 0.0 | 2.1 | GO:0043679 | axon terminus(GO:0043679) |
| 0.0 | 0.1 | GO:0032021 | NELF complex(GO:0032021) |
| 0.0 | 0.3 | GO:0033202 | Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202) |
| 0.0 | 0.1 | GO:0005960 | glycine cleavage complex(GO:0005960) |
| 0.0 | 1.0 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.0 | 0.3 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.0 | 0.4 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.0 | 2.0 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 0.9 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 1.0 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.0 | 0.1 | GO:0070652 | HAUS complex(GO:0070652) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 1.1 | GO:0035651 | AP-3 adaptor complex binding(GO:0035651) |
| 0.4 | 1.1 | GO:0052798 | beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798) |
| 0.4 | 1.4 | GO:0004461 | lactose synthase activity(GO:0004461) |
| 0.4 | 1.8 | GO:0034988 | Fc-gamma receptor I complex binding(GO:0034988) |
| 0.3 | 6.2 | GO:0005432 | calcium:sodium antiporter activity(GO:0005432) |
| 0.3 | 3.6 | GO:0102337 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.3 | 1.3 | GO:0045569 | TRAIL binding(GO:0045569) |
| 0.3 | 1.9 | GO:0004489 | methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489) |
| 0.3 | 3.9 | GO:0031014 | troponin T binding(GO:0031014) |
| 0.3 | 7.1 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.2 | 1.3 | GO:0004310 | farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996) |
| 0.2 | 2.1 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 0.2 | 0.8 | GO:0008184 | glycogen phosphorylase activity(GO:0008184) |
| 0.2 | 2.4 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
| 0.2 | 4.4 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
| 0.2 | 0.9 | GO:0005152 | interleukin-1 receptor antagonist activity(GO:0005152) |
| 0.2 | 2.0 | GO:0004972 | NMDA glutamate receptor activity(GO:0004972) |
| 0.2 | 0.5 | GO:0098973 | structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973) |
| 0.2 | 0.8 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
| 0.2 | 0.8 | GO:0047374 | methylumbelliferyl-acetate deacetylase activity(GO:0047374) |
| 0.2 | 0.9 | GO:1990254 | keratin filament binding(GO:1990254) |
| 0.1 | 1.2 | GO:0008048 | calcium sensitive guanylate cyclase activator activity(GO:0008048) |
| 0.1 | 0.6 | GO:0010851 | cyclase regulator activity(GO:0010851) |
| 0.1 | 0.4 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
| 0.1 | 3.7 | GO:0048018 | receptor agonist activity(GO:0048018) |
| 0.1 | 1.1 | GO:0043426 | MRF binding(GO:0043426) |
| 0.1 | 1.4 | GO:0019215 | intermediate filament binding(GO:0019215) |
| 0.1 | 0.5 | GO:0035614 | snRNA stem-loop binding(GO:0035614) |
| 0.1 | 1.4 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
| 0.1 | 7.5 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.1 | 0.5 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
| 0.1 | 0.4 | GO:0003985 | acetyl-CoA C-acetyltransferase activity(GO:0003985) |
| 0.1 | 0.9 | GO:0010859 | calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859) |
| 0.1 | 0.6 | GO:0017108 | 5'-flap endonuclease activity(GO:0017108) |
| 0.1 | 1.1 | GO:0016868 | intramolecular transferase activity, phosphotransferases(GO:0016868) |
| 0.1 | 1.0 | GO:0051434 | BH3 domain binding(GO:0051434) |
| 0.1 | 0.4 | GO:0047237 | glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237) glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238) |
| 0.1 | 0.9 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.1 | 1.9 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.1 | 0.3 | GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827) |
| 0.1 | 0.7 | GO:0036310 | annealing helicase activity(GO:0036310) |
| 0.1 | 0.6 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
| 0.1 | 0.3 | GO:0052655 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
| 0.1 | 1.2 | GO:0098748 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.1 | 1.2 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.1 | 3.9 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.1 | 1.4 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
| 0.1 | 0.7 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
| 0.1 | 2.6 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
| 0.1 | 0.6 | GO:1990459 | transferrin receptor binding(GO:1990459) |
| 0.1 | 0.9 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.1 | 0.2 | GO:0061598 | nitrate reductase activity(GO:0008940) molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599) |
| 0.1 | 0.5 | GO:0004897 | ciliary neurotrophic factor receptor activity(GO:0004897) |
| 0.1 | 0.7 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.0 | 0.7 | GO:0048406 | nerve growth factor binding(GO:0048406) |
| 0.0 | 0.4 | GO:1990599 | 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599) |
| 0.0 | 0.4 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
| 0.0 | 0.5 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
| 0.0 | 0.9 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.0 | 0.2 | GO:0017089 | glycolipid transporter activity(GO:0017089) |
| 0.0 | 1.2 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.0 | 1.1 | GO:0072349 | modified amino acid transmembrane transporter activity(GO:0072349) |
| 0.0 | 0.1 | GO:0004992 | platelet activating factor receptor activity(GO:0004992) |
| 0.0 | 0.3 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
| 0.0 | 0.2 | GO:0042020 | interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020) |
| 0.0 | 0.6 | GO:0015245 | fatty acid transporter activity(GO:0015245) |
| 0.0 | 2.0 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.0 | 0.3 | GO:0019136 | deoxynucleoside kinase activity(GO:0019136) |
| 0.0 | 0.7 | GO:0008417 | fucosyltransferase activity(GO:0008417) |
| 0.0 | 0.9 | GO:0031432 | titin binding(GO:0031432) |
| 0.0 | 0.6 | GO:0015250 | water channel activity(GO:0015250) |
| 0.0 | 0.8 | GO:0032183 | SUMO binding(GO:0032183) |
| 0.0 | 0.4 | GO:0070679 | inositol 1,4,5 trisphosphate binding(GO:0070679) |
| 0.0 | 0.3 | GO:0004117 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) |
| 0.0 | 0.4 | GO:0033691 | sialic acid binding(GO:0033691) |
| 0.0 | 1.0 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.0 | 0.5 | GO:0019957 | C-C chemokine binding(GO:0019957) |
| 0.0 | 1.8 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.0 | 0.5 | GO:0042834 | peptidoglycan binding(GO:0042834) |
| 0.0 | 0.9 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 0.9 | GO:0008198 | ferrous iron binding(GO:0008198) |
| 0.0 | 1.2 | GO:0008188 | neuropeptide receptor activity(GO:0008188) |
| 0.0 | 0.3 | GO:0015143 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
| 0.0 | 1.2 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.0 | 0.4 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
| 0.0 | 0.5 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
| 0.0 | 0.4 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.0 | 0.8 | GO:0030506 | ankyrin binding(GO:0030506) |
| 0.0 | 0.5 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.0 | 0.8 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.0 | 0.3 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.0 | 0.7 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 0.0 | 1.7 | GO:0019843 | rRNA binding(GO:0019843) |
| 0.0 | 0.5 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
| 0.0 | 1.0 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
| 0.0 | 0.1 | GO:0008413 | 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539) |
| 0.0 | 0.2 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
| 0.0 | 4.5 | GO:0008201 | heparin binding(GO:0008201) |
| 0.0 | 0.1 | GO:0051185 | coenzyme transporter activity(GO:0051185) |
| 0.0 | 0.3 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.0 | 0.1 | GO:0060175 | brain-derived neurotrophic factor-activated receptor activity(GO:0060175) |
| 0.0 | 0.4 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
| 0.0 | 1.1 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
| 0.0 | 1.2 | GO:0005080 | protein kinase C binding(GO:0005080) |
| 0.0 | 0.5 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.0 | 1.4 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 0.1 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 0.0 | 0.6 | GO:0008301 | DNA binding, bending(GO:0008301) |
| 0.0 | 0.3 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 0.0 | 0.3 | GO:0016755 | transferase activity, transferring amino-acyl groups(GO:0016755) |
| 0.0 | 0.4 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.0 | 0.7 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.0 | 0.3 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.0 | 0.2 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.0 | 0.2 | GO:0008061 | chitin binding(GO:0008061) |
| 0.0 | 0.4 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.0 | 0.1 | GO:0047499 | calcium-independent phospholipase A2 activity(GO:0047499) |
| 0.0 | 0.2 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 0.0 | 0.4 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.0 | 0.9 | GO:0001540 | beta-amyloid binding(GO:0001540) |
| 0.0 | 5.2 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.0 | 1.0 | GO:0030276 | clathrin binding(GO:0030276) |
| 0.0 | 0.3 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.0 | 0.4 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.0 | 0.3 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.0 | 0.6 | GO:0016814 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814) |
| 0.0 | 0.3 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 0.0 | 0.1 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 9.1 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.1 | 4.4 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.1 | 3.9 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
| 0.1 | 6.5 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.1 | 1.7 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.0 | 1.6 | SA PTEN PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
| 0.0 | 0.8 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 0.0 | 2.1 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
| 0.0 | 1.0 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.0 | 1.1 | PID WNT CANONICAL PATHWAY | Canonical Wnt signaling pathway |
| 0.0 | 2.5 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.0 | 1.5 | PID PS1 PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.0 | 2.3 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.0 | 1.0 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.0 | 0.3 | SA TRKA RECEPTOR | The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. |
| 0.0 | 3.0 | PID E2F PATHWAY | E2F transcription factor network |
| 0.0 | 1.4 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.0 | 1.0 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
| 0.0 | 0.7 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 0.0 | 1.9 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.0 | 1.5 | PID ARF6 TRAFFICKING PATHWAY | Arf6 trafficking events |
| 0.0 | 0.8 | ST WNT CA2 CYCLIC GMP PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 0.0 | 0.4 | PID NFKAPPAB ATYPICAL PATHWAY | Atypical NF-kappaB pathway |
| 0.0 | 1.3 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.0 | 1.0 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.0 | 0.5 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.0 | 4.8 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 0.4 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.0 | 0.7 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.0 | 0.2 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.0 | 0.4 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.0 | 0.4 | PID REELIN PATHWAY | Reelin signaling pathway |
| 0.0 | 0.5 | SIG CHEMOTAXIS | Genes related to chemotaxis |
| 0.0 | 0.4 | PID IL23 PATHWAY | IL23-mediated signaling events |
| 0.0 | 1.7 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 8.2 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.2 | 7.1 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.1 | 3.8 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.1 | 2.5 | REACTOME P2Y RECEPTORS | Genes involved in P2Y receptors |
| 0.1 | 4.2 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.1 | 4.8 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.1 | 1.5 | REACTOME CALNEXIN CALRETICULIN CYCLE | Genes involved in Calnexin/calreticulin cycle |
| 0.1 | 2.6 | REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
| 0.1 | 1.1 | REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
| 0.1 | 0.4 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.1 | 0.7 | REACTOME PACKAGING OF TELOMERE ENDS | Genes involved in Packaging Of Telomere Ends |
| 0.1 | 3.9 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.1 | 1.4 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.1 | 2.8 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 0.1 | 1.2 | REACTOME GAP JUNCTION DEGRADATION | Genes involved in Gap junction degradation |
| 0.1 | 0.9 | REACTOME G2 M DNA DAMAGE CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.0 | 0.8 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 0.0 | 1.6 | REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
| 0.0 | 1.1 | REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
| 0.0 | 1.1 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.0 | 0.8 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.0 | 0.5 | REACTOME GLYCOPROTEIN HORMONES | Genes involved in Glycoprotein hormones |
| 0.0 | 1.6 | REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION | Genes involved in Unblocking of NMDA receptor, glutamate binding and activation |
| 0.0 | 0.6 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.0 | 0.4 | REACTOME ERKS ARE INACTIVATED | Genes involved in ERKs are inactivated |
| 0.0 | 1.4 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.0 | 2.1 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.0 | 1.0 | REACTOME INFLAMMASOMES | Genes involved in Inflammasomes |
| 0.0 | 1.4 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.0 | 1.2 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.0 | 1.3 | REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE | Genes involved in Formation of Fibrin Clot (Clotting Cascade) |
| 0.0 | 0.6 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.0 | 0.4 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 0.0 | 1.9 | REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 | Genes involved in SCF(Skp2)-mediated degradation of p27/p21 |
| 0.0 | 0.9 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.0 | 0.4 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.0 | 1.8 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.0 | 0.6 | REACTOME BETA DEFENSINS | Genes involved in Beta defensins |
| 0.0 | 0.7 | REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB | Genes involved in PKA-mediated phosphorylation of CREB |
| 0.0 | 1.8 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 0.0 | 2.2 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.0 | 0.5 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.0 | 0.3 | REACTOME RETROGRADE NEUROTROPHIN SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
| 0.0 | 0.3 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.0 | 1.3 | REACTOME ASPARAGINE N LINKED GLYCOSYLATION | Genes involved in Asparagine N-linked glycosylation |
| 0.0 | 0.8 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.0 | 0.2 | REACTOME PLATELET SENSITIZATION BY LDL | Genes involved in Platelet sensitization by LDL |
| 0.0 | 0.3 | REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
| 0.0 | 0.4 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.0 | 0.6 | REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING | Genes involved in Integrin alphaIIb beta3 signaling |
| 0.0 | 1.3 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.0 | 0.4 | REACTOME LYSOSOME VESICLE BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 0.0 | 0.3 | REACTOME FORMATION OF INCISION COMPLEX IN GG NER | Genes involved in Formation of incision complex in GG-NER |
| 0.0 | 0.2 | REACTOME ENOS ACTIVATION AND REGULATION | Genes involved in eNOS activation and regulation |
| 0.0 | 0.3 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.0 | 0.9 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.0 | 0.3 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.0 | 0.3 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.0 | 0.8 | REACTOME PROTEIN FOLDING | Genes involved in Protein folding |