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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for EPAS1_BCL3

Z-value: 1.27

Motif logo

Transcription factors associated with EPAS1_BCL3

Gene Symbol Gene ID Gene Info
ENSG00000116016.14 EPAS1
ENSG00000069399.15 BCL3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EPAS1hg38_v1_chr2_+_46297397_46297414-0.232.2e-01Click!
BCL3hg38_v1_chr19_+_44751251_44751321-0.183.4e-01Click!

Activity profile of EPAS1_BCL3 motif

Sorted Z-values of EPAS1_BCL3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of EPAS1_BCL3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr15_+_40351026 1.92 ENST00000448599.2
proline, histidine and glycine rich 1
chr7_+_154305256 1.89 ENST00000619756.4
dipeptidyl peptidase like 6
chr12_+_56021316 1.67 ENST00000547791.2
IKAROS family zinc finger 4
chr3_-_116444983 1.43 ENST00000333617.8
limbic system associated membrane protein
chr20_-_2800576 1.39 ENST00000380605.3
carboxypeptidase X, M14 family member 1
chr20_-_45115149 1.38 ENST00000307971.7
ENST00000372789.5
WAP four-disulfide core domain 5
chr16_+_82626955 1.34 ENST00000268613.14
ENST00000567109.6
ENST00000565636.5
ENST00000431540.7
ENST00000428848.7
cadherin 13
chr1_+_158254414 1.28 ENST00000289429.6
CD1a molecule
chr19_+_35138778 1.22 ENST00000351325.9
ENST00000586871.5
ENST00000592174.1
FXYD domain containing ion transport regulator 1
novel transcript
chr1_+_152514474 1.19 ENST00000368790.4
cysteine rich C-terminal 1
chr2_+_237566574 1.18 ENST00000165524.1
prolactin releasing hormone
chr17_+_21376321 1.16 ENST00000583088.6
potassium inwardly rectifying channel subfamily J member 12
chr6_-_6007511 1.05 ENST00000616243.1
neuritin 1
chr20_+_44715360 1.03 ENST00000190983.5
cellular communication network factor 5
chr10_-_97185758 1.00 ENST00000371070.8
slit guidance ligand 1
chr3_-_187291882 0.98 ENST00000392470.6
ENST00000169293.10
ENST00000439271.1
ENST00000392472.6
ENST00000392475.2
mannan binding lectin serine peptidase 1
chr16_-_11273610 0.97 ENST00000327157.4
protamine 3
chr16_+_1528674 0.96 ENST00000253934.9
transmembrane protein 204
chr9_+_34652167 0.95 ENST00000441545.7
ENST00000553620.5
interleukin 11 receptor subunit alpha
chr12_-_2835018 0.94 ENST00000337508.9
nuclear receptor interacting protein 2
chrX_+_1268807 0.94 ENST00000381524.8
ENST00000381529.9
ENST00000412290.6
colony stimulating factor 2 receptor subunit alpha
chr7_+_148339452 0.90 ENST00000463592.3
contactin associated protein 2
chr16_+_4958289 0.89 ENST00000251170.12
SEC14 like lipid binding 5
chr16_-_20669855 0.88 ENST00000524149.5
acyl-CoA synthetase medium chain family member 1
chr1_-_39691450 0.87 ENST00000612703.3
ENST00000617690.2
hippocalcin like 4
chr20_+_44714835 0.86 ENST00000372868.6
cellular communication network factor 5
chr14_+_32934383 0.86 ENST00000551634.6
neuronal PAS domain protein 3
chr8_-_69834970 0.85 ENST00000260126.9
solute carrier organic anion transporter family member 5A1
chr14_-_94509469 0.84 ENST00000677451.1
serpin family A member 12
chr19_-_8981342 0.83 ENST00000397910.8
mucin 16, cell surface associated
chr12_+_26195647 0.81 ENST00000535504.1
sarcospan
chr8_-_139704091 0.80 ENST00000648164.1
potassium two pore domain channel subfamily K member 9
chr11_+_65833944 0.77 ENST00000308342.7
sorting nexin 32
chr19_+_35138993 0.77 ENST00000612146.4
ENST00000589209.5
FXYD domain containing ion transport regulator 1
chr7_-_36724380 0.75 ENST00000617267.4
acyloxyacyl hydrolase
chr8_+_27491125 0.75 ENST00000517536.5
ENST00000521400.6
ENST00000521780.5
ENST00000380476.7
ENST00000518379.5
ENST00000521684.1
epoxide hydrolase 2
chr20_+_44714853 0.75 ENST00000372865.4
cellular communication network factor 5
chrX_+_1268786 0.74 ENST00000501036.7
ENST00000417535.7
colony stimulating factor 2 receptor subunit alpha
chr16_+_72056153 0.73 ENST00000576168.6
ENST00000567185.7
ENST00000567612.2
haptoglobin
chr3_-_128493173 0.72 ENST00000498200.1
ENST00000341105.7
GATA binding protein 2
chr11_+_10450627 0.70 ENST00000396554.7
ENST00000524866.5
adenosine monophosphate deaminase 3
chr7_-_38368169 0.69 ENST00000390348.2
T cell receptor gamma variable 1 (non-functional)
chr7_-_76409682 0.69 ENST00000275560.4
scavenger receptor cysteine rich family member with 4 domains
chr19_-_48513161 0.68 ENST00000673139.1
lemur tyrosine kinase 3
chr10_-_133336862 0.66 ENST00000368555.3
ENST00000252939.9
ENST00000368558.1
calcyon neuron specific vesicular protein
chr8_+_76683779 0.64 ENST00000523885.2
zinc finger homeobox 4
chr3_-_127823177 0.64 ENST00000434178.6
monoglyceride lipase
chr11_-_75351609 0.63 ENST00000420843.7
arrestin beta 1
chr7_-_36724457 0.63 ENST00000617537.5
ENST00000435386.1
acyloxyacyl hydrolase
chr19_+_35139724 0.62 ENST00000588715.5
ENST00000588607.5
FXYD domain containing ion transport regulator 1
chr3_-_127823235 0.62 ENST00000398104.5
monoglyceride lipase
chr9_+_87498491 0.62 ENST00000622514.4
death associated protein kinase 1
chr6_+_146027662 0.62 ENST00000492807.6
ENST00000361719.6
glutamate metabotropic receptor 1
chr6_-_152563271 0.61 ENST00000535896.7
ENST00000672122.1
spectrin repeat containing nuclear envelope protein 1
chr3_+_127629161 0.61 ENST00000342480.7
podocalyxin like 2
chr9_+_87497852 0.60 ENST00000408954.8
death associated protein kinase 1
chr2_-_27119099 0.60 ENST00000402550.5
ENST00000402394.6
cell growth regulator with EF-hand domain 1
chr2_+_219572304 0.60 ENST00000243786.3
inhibin subunit alpha
chr3_-_127822835 0.60 ENST00000453507.6
monoglyceride lipase
chr19_+_35139440 0.59 ENST00000455515.6
FXYD domain containing ion transport regulator 1
chr11_+_10450289 0.59 ENST00000444303.6
adenosine monophosphate deaminase 3
chr14_+_41608344 0.58 ENST00000554120.5
leucine rich repeat and fibronectin type III domain containing 5
chr2_+_209579429 0.58 ENST00000361559.8
microtubule associated protein 2
chr7_-_38330935 0.58 ENST00000390343.2
T cell receptor gamma variable 8
chr10_-_5499544 0.58 ENST00000380332.5
calmodulin like 5
chr19_+_30372364 0.58 ENST00000355537.4
zinc finger protein 536
chr15_-_65422894 0.56 ENST00000352385.3
immunoglobulin superfamily DCC subclass member 4
chr4_-_16084002 0.55 ENST00000447510.7
prominin 1
chr9_+_87497222 0.54 ENST00000358077.9
death associated protein kinase 1
chr1_+_109656092 0.54 ENST00000369836.9
ENST00000326729.9
glutathione S-transferase mu 4
chr3_-_193554952 0.54 ENST00000392443.7
ATPase 13A4
chr18_-_23662810 0.54 ENST00000322980.13
ankyrin repeat domain 29
chr19_+_37371092 0.53 ENST00000436120.7
zinc finger protein 527
chr1_-_39691393 0.53 ENST00000372844.8
hippocalcin like 4
chr15_+_47717344 0.53 ENST00000558816.5
ENST00000536845.7
semaphorin 6D
chr1_-_26360050 0.52 ENST00000475866.3
crystallin beta-gamma domain containing 2
chr2_-_85418421 0.52 ENST00000409275.1
capping actin protein, gelsolin like
chr2_+_30231524 0.51 ENST00000395323.9
ENST00000406087.5
ENST00000404397.5
LBH regulator of WNT signaling pathway
chr9_+_18474100 0.50 ENST00000327883.11
ENST00000431052.6
ENST00000380570.8
ENST00000380548.9
ADAMTS like 1
chr1_+_153678680 0.50 ENST00000368680.4
natriuretic peptide receptor 1
chr15_+_74173693 0.50 ENST00000249842.8
immunoglobulin superfamily containing leucine rich repeat
chr22_-_37484505 0.50 ENST00000442496.1
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr3_-_185152974 0.50 ENST00000335012.3
chromosome 3 open reading frame 70
chr1_+_109656322 0.49 ENST00000369833.5
ENST00000336075.6
ENST00000638994.1
glutathione S-transferase mu 4
chr22_+_39456996 0.49 ENST00000341184.7
beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
chr3_+_134795248 0.49 ENST00000398015.8
EPH receptor B1
chr10_+_100462969 0.48 ENST00000343737.6
Wnt family member 8B
chr3_+_113211539 0.48 ENST00000682979.1
ENST00000485230.5
BOC cell adhesion associated, oncogene regulated
chr7_-_132576463 0.48 ENST00000423507.6
plexin A4
chr13_-_98752619 0.48 ENST00000376503.10
solute carrier family 15 member 1
chr17_-_43545707 0.48 ENST00000545089.5
ETS variant transcription factor 4
chr8_+_109086585 0.48 ENST00000518632.2
thyrotropin releasing hormone receptor
chr7_-_38349972 0.47 ENST00000390344.2
T cell receptor gamma variable 5
chr22_-_30574572 0.47 ENST00000402369.5
galactose-3-O-sulfotransferase 1
chr1_-_21345531 0.47 ENST00000649812.1
endothelin converting enzyme 1
chr19_-_35134861 0.47 ENST00000591633.2
leucine rich repeat LGI family member 4
chr21_-_29939912 0.47 ENST00000399907.5
ENST00000399909.5
glutamate ionotropic receptor kainate type subunit 1
chr19_+_56404314 0.46 ENST00000333201.13
ENST00000391778.3
zinc finger protein 583
chr19_+_53521245 0.46 ENST00000649326.1
zinc finger protein 331
chr1_+_203626775 0.46 ENST00000367218.7
ATPase plasma membrane Ca2+ transporting 4
chrX_-_20116871 0.46 ENST00000379651.7
ENST00000443379.7
ENST00000379643.10
MAP7 domain containing 2
chr17_-_43546323 0.46 ENST00000545954.5
ENST00000319349.10
ETS variant transcription factor 4
chr17_-_7207245 0.45 ENST00000649971.1
discs large MAGUK scaffold protein 4
chr1_+_218346235 0.45 ENST00000366929.4
transforming growth factor beta 2
chr8_+_10672623 0.45 ENST00000304519.10
chromosome 8 open reading frame 74
chr3_-_193554885 0.45 ENST00000342695.9
ATPase 13A4
chr14_+_104724221 0.45 ENST00000330877.7
adenylosuccinate synthase 1
chr8_+_22057857 0.44 ENST00000517305.4
ENST00000265800.9
ENST00000517418.5
dematin actin binding protein
chr17_-_7114240 0.43 ENST00000446679.6
asialoglycoprotein receptor 2
chr17_+_8039106 0.43 ENST00000573359.1
arachidonate 15-lipoxygenase type B
chr11_+_117986386 0.43 ENST00000227752.8
interleukin 10 receptor subunit alpha
chr9_+_72577939 0.43 ENST00000645773.1
transmembrane channel like 1
chr18_+_63777773 0.43 ENST00000447428.5
ENST00000546027.5
serpin family B member 7
chr1_-_44031352 0.43 ENST00000372306.7
ENST00000475075.6
solute carrier family 6 member 9
chr7_+_74773962 0.43 ENST00000289473.10
neutrophil cytosolic factor 1
chr5_-_11588842 0.43 ENST00000503622.5
catenin delta 2
chr9_-_14910421 0.43 ENST00000380880.4
FRAS1 related extracellular matrix 1
chr19_+_37594830 0.43 ENST00000589117.5
zinc finger protein 540
chr14_+_70641896 0.43 ENST00000256367.3
tetratricopeptide repeat domain 9
chr12_+_120650492 0.43 ENST00000351200.6
calcium binding protein 1
chr1_-_23424692 0.42 ENST00000374601.7
ENST00000450454.7
transcription elongation factor A3
chr18_-_23662868 0.42 ENST00000586087.1
ENST00000592179.6
ankyrin repeat domain 29
chr14_+_96039328 0.42 ENST00000553764.1
ENST00000555004.3
ENST00000556728.1
ENST00000553782.1
chromosome 14 open reading frame 132
chrX_+_130171903 0.42 ENST00000257017.5
RAB33A, member RAS oncogene family
chr12_-_7665897 0.42 ENST00000229304.5
apolipoprotein B mRNA editing enzyme catalytic subunit 1
chr2_+_209579399 0.42 ENST00000360351.8
microtubule associated protein 2
chr17_-_76027296 0.42 ENST00000301607.8
envoplakin
chr9_-_114930508 0.41 ENST00000223795.3
ENST00000618336.4
TNF superfamily member 8
chr8_+_144107733 0.41 ENST00000323662.9
WD repeat domain 97
chr19_-_42937201 0.41 ENST00000406070.7
pregnancy specific beta-1-glycoprotein 7
chr19_+_55857437 0.41 ENST00000587891.5
NLR family pyrin domain containing 4
chrX_-_75523011 0.40 ENST00000373367.8
zinc finger DHHC-type palmitoyltransferase 15
chr17_-_74859863 0.40 ENST00000293190.10
glutamate ionotropic receptor NMDA type subunit 2C
chr8_+_62248591 0.40 ENST00000519049.6
sodium/potassium transporting ATPase interacting 3
chr2_+_209579598 0.40 ENST00000445941.5
ENST00000673860.1
microtubule associated protein 2
chr2_-_27119012 0.39 ENST00000312734.8
cell growth regulator with EF-hand domain 1
chr9_+_72628020 0.39 ENST00000646619.1
transmembrane channel like 1
chr9_+_87497675 0.39 ENST00000472284.5
ENST00000469640.6
death associated protein kinase 1
chr14_+_79279403 0.39 ENST00000281127.11
neurexin 3
chr5_-_148654130 0.39 ENST00000360693.7
5-hydroxytryptamine receptor 4
chr5_+_167754918 0.38 ENST00000519204.5
teneurin transmembrane protein 2
chr16_+_66603874 0.38 ENST00000563672.5
ENST00000424011.6
CKLF like MARVEL transmembrane domain containing 3
chr11_-_111912871 0.38 ENST00000528628.5
crystallin alpha B
chr7_+_154305105 0.37 ENST00000332007.7
dipeptidyl peptidase like 6
chr8_+_68330923 0.37 ENST00000518698.6
chromosome 8 open reading frame 34
chr1_-_44031446 0.37 ENST00000372310.8
ENST00000466926.1
solute carrier family 6 member 9
chr16_+_50693568 0.37 ENST00000647318.2
ENST00000531674.1
nucleotide binding oligomerization domain containing 2
chr9_+_92974476 0.37 ENST00000337352.10
FYVE, RhoGEF and PH domain containing 3
chr1_+_13584262 0.37 ENST00000376061.8
ENST00000513143.5
podoplanin
chr2_+_74002685 0.37 ENST00000305799.8
tet methylcytosine dioxygenase 3
chr1_+_13583762 0.37 ENST00000376057.8
ENST00000621990.5
ENST00000510906.5
podoplanin
chr4_+_157220691 0.37 ENST00000509417.5
ENST00000645636.1
ENST00000296526.12
ENST00000264426.14
glutamate ionotropic receptor AMPA type subunit 2
chr9_+_101028721 0.36 ENST00000374874.8
phospholipid phosphatase related 1
chr19_-_50511146 0.36 ENST00000594350.1
ENST00000601423.5
Josephin domain containing 2
chr16_+_71626149 0.36 ENST00000567566.1
MARVEL domain containing 3
chr4_-_108167784 0.36 ENST00000438313.6
lymphoid enhancer binding factor 1
chr19_-_9792991 0.36 ENST00000592587.1
zinc finger protein 846
chr20_+_58689124 0.36 ENST00000525967.5
ENST00000525817.5
aminopeptidase like 1
chr19_+_35292145 0.36 ENST00000595791.5
ENST00000597035.5
ENST00000537831.2
ENST00000392213.8
myelin associated glycoprotein
chr2_+_33476640 0.36 ENST00000425210.5
ENST00000444784.5
ENST00000423159.5
ENST00000403687.8
RAS guanyl releasing protein 3
chr3_-_127822455 0.36 ENST00000265052.10
monoglyceride lipase
chrX_+_102651366 0.36 ENST00000415986.5
ENST00000444152.5
ENST00000361600.9
G protein-coupled receptor associated sorting protein 1
chr7_-_132576493 0.35 ENST00000321063.8
plexin A4
chr21_-_29939532 0.35 ENST00000327783.8
ENST00000389124.6
ENST00000389125.7
ENST00000399913.5
glutamate ionotropic receptor kainate type subunit 1
chr17_-_7204502 0.35 ENST00000486626.8
ENST00000648263.1
discs large MAGUK scaffold protein 4
chr19_-_11577632 0.35 ENST00000590420.1
ENST00000648477.1
acid phosphatase 5, tartrate resistant
chr2_-_219571529 0.35 ENST00000404537.6
obscurin like cytoskeletal adaptor 1
chr12_-_23949642 0.35 ENST00000537393.5
ENST00000451604.7
ENST00000381381.6
SRY-box transcription factor 5
chr19_-_51723968 0.35 ENST00000222115.5
ENST00000540069.7
hyaluronan synthase 1
chr8_-_133297092 0.35 ENST00000522890.5
ENST00000675983.1
ENST00000518176.5
ENST00000323851.13
ENST00000522476.5
ENST00000518066.5
ENST00000521544.5
ENST00000674605.1
ENST00000518480.5
ENST00000523892.5
N-myc downstream regulated 1
chr4_+_40196907 0.35 ENST00000622175.4
ENST00000619474.4
ENST00000615083.4
ENST00000610353.4
ENST00000614836.1
ras homolog family member H
chr12_+_50057548 0.35 ENST00000228468.8
ENST00000447966.7
acid sensing ion channel subunit 1
chrX_+_102651476 0.34 ENST00000537097.2
G protein-coupled receptor associated sorting protein 1
chr18_+_65751000 0.34 ENST00000397968.4
cadherin 7
chr1_+_20290869 0.34 ENST00000289815.13
ENST00000375079.6
von Willebrand factor A domain containing 5B1
chr4_-_56681588 0.34 ENST00000554144.5
ENST00000381260.7
HOP homeobox
chr2_-_2331336 0.34 ENST00000648933.1
ENST00000644820.1
myelin transcription factor 1 like
chr16_+_66604100 0.33 ENST00000562357.5
ENST00000562707.5
ENST00000361909.8
ENST00000460097.5
ENST00000565666.5
CKLF like MARVEL transmembrane domain containing 3
chr17_+_1279655 0.33 ENST00000333813.4
trafficking regulator of GLUT4 (SLC2A4) 1
chr16_+_981762 0.33 ENST00000293894.4
SRY-box transcription factor 8
chr15_-_64046322 0.33 ENST00000457488.5
ENST00000612884.4
death associated protein kinase 2
chr2_-_27118900 0.33 ENST00000405600.5
ENST00000260595.9
cell growth regulator with EF-hand domain 1
chr7_+_1709162 0.33 ENST00000561626.3
extracellular leucine rich repeat and fibronectin type III domain containing 1
chr9_-_14722725 0.33 ENST00000380911.4
cerberus 1, DAN family BMP antagonist
chr1_+_228165794 0.32 ENST00000366711.4
iron-sulfur cluster assembly factor IBA57
chr4_+_157220654 0.32 ENST00000393815.6
glutamate ionotropic receptor AMPA type subunit 2
chr3_-_184017863 0.32 ENST00000427120.6
ENST00000334444.11
ENST00000392579.6
ENST00000382494.6
ENST00000265586.10
ENST00000446941.2
ATP binding cassette subfamily C member 5
chr14_-_24429665 0.32 ENST00000267406.11
cerebellin 3 precursor
chr4_+_40197023 0.32 ENST00000381799.10
ras homolog family member H
chr16_+_4371840 0.32 ENST00000304735.4
vasorin
chr9_-_127877665 0.32 ENST00000644144.2
adenylate kinase 1
chr2_-_218831791 0.32 ENST00000439262.6
ENST00000430489.1
protein kinase AMP-activated non-catalytic subunit gamma 3
chr7_+_142111739 0.32 ENST00000550469.6
ENST00000477922.3
maltase-glucoamylase 2 (putative)
chr7_+_101127095 0.32 ENST00000223095.5
serpin family E member 1
chr10_+_110207587 0.32 ENST00000332674.9
ENST00000453116.5
MAX interactor 1, dimerization protein
chr19_-_50511203 0.31 ENST00000595669.5
Josephin domain containing 2
chr5_+_146338835 0.31 ENST00000646991.2
POU class 4 homeobox 3
chr8_-_88327475 0.31 ENST00000286614.11
matrix metallopeptidase 16
chr22_+_22818994 0.31 ENST00000390316.2
immunoglobulin lambda variable 3-9
chr8_-_72075575 0.31 ENST00000262209.5
transient receptor potential cation channel subfamily A member 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.2 GO:0010732 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.4 1.2 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.3 1.0 GO:0018874 benzoate metabolic process(GO:0018874)
0.3 0.9 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.3 0.8 GO:0021793 chemorepulsion of branchiomotor axon(GO:0021793)
0.3 0.8 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
0.2 2.2 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.2 0.7 GO:1990764 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.2 0.7 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.2 1.4 GO:0006196 AMP catabolic process(GO:0006196)
0.2 1.3 GO:0018916 nitrobenzene metabolic process(GO:0018916)
0.2 0.6 GO:0072034 renal vesicle induction(GO:0072034)
0.2 0.6 GO:0099557 trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission(GO:0099557)
0.2 0.9 GO:0071109 superior temporal gyrus development(GO:0071109)
0.2 0.7 GO:0035854 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.2 0.8 GO:1901205 regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204) negative regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901205)
0.2 0.5 GO:0042938 dipeptide transport(GO:0042938)
0.2 0.9 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.2 0.5 GO:1905006 negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905006)
0.1 0.4 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310) regulation of mRNA modification(GO:0090365)
0.1 0.7 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.1 1.3 GO:0055096 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.1 1.5 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.1 0.4 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.1 0.1 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.1 0.4 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.4 GO:0044725 chromatin reprogramming in the zygote(GO:0044725)
0.1 0.4 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 0.5 GO:2000910 negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
0.1 0.8 GO:2000035 regulation of stem cell division(GO:2000035)
0.1 0.7 GO:1901731 positive regulation of platelet aggregation(GO:1901731)
0.1 1.1 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.1 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 0.4 GO:0046882 negative regulation of B cell differentiation(GO:0045578) negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.1 0.4 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1 0.4 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 2.2 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.1 0.6 GO:0071895 odontoblast differentiation(GO:0071895)
0.1 0.5 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 0.4 GO:1903755 regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
0.1 0.4 GO:0060584 detection of peptidoglycan(GO:0032499) activation of MAPK activity involved in innate immune response(GO:0035419) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 0.3 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 0.5 GO:0050968 detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.1 0.4 GO:0050915 sensory perception of sour taste(GO:0050915)
0.1 0.3 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1 1.1 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 2.3 GO:0035641 locomotory exploration behavior(GO:0035641)
0.1 0.4 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.4 GO:1902943 regulation of voltage-gated chloride channel activity(GO:1902941) positive regulation of voltage-gated chloride channel activity(GO:1902943)
0.1 0.5 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 0.4 GO:0003419 growth plate cartilage chondrocyte proliferation(GO:0003419)
0.1 0.3 GO:0002325 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.1 0.8 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.3 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.1 0.4 GO:0033058 directional locomotion(GO:0033058)
0.1 0.6 GO:2000768 positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.1 0.2 GO:1905237 response to cyclosporin A(GO:1905237) positive regulation of response to drug(GO:2001025)
0.1 0.2 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 0.3 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.1 0.2 GO:1903004 regulation of protein K63-linked deubiquitination(GO:1903004) positive regulation of protein K63-linked deubiquitination(GO:1903006)
0.1 0.1 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.1 0.8 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.2 GO:0071206 establishment of protein localization to juxtaparanode region of axon(GO:0071206)
0.1 0.2 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1 0.2 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.1 0.2 GO:0099624 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372) atrial cardiac muscle cell membrane repolarization(GO:0099624)
0.1 0.2 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.1 0.3 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.1 0.6 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.1 0.9 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.1 0.2 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.1 0.8 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.1 0.3 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.1 0.2 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.1 0.2 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.1 1.0 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.2 GO:0072096 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.1 0.2 GO:0051885 positive regulation of anagen(GO:0051885)
0.1 0.5 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 0.2 GO:0006172 ADP biosynthetic process(GO:0006172) purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183)
0.1 0.2 GO:0043091 L-arginine import(GO:0043091) arginine import(GO:0090467)
0.1 0.2 GO:0052331 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.1 0.2 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.1 0.2 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.1 0.4 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.1 0.1 GO:0003099 positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.1 0.2 GO:0034443 negative regulation of lipoprotein oxidation(GO:0034443)
0.1 0.3 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.1 GO:0003275 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.1 0.4 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.1 0.2 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.1 0.2 GO:1904327 tail-anchored membrane protein insertion into ER membrane(GO:0071816) protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1 0.5 GO:0015886 heme transport(GO:0015886)
0.1 0.4 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.1 0.2 GO:0010157 response to chlorate(GO:0010157)
0.1 0.2 GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.0 0.5 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.3 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.0 0.2 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.0 0.1 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.0 0.6 GO:1902414 protein localization to cell junction(GO:1902414)
0.0 0.1 GO:0099538 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.0 0.7 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.2 GO:0042494 detection of bacterial lipoprotein(GO:0042494)
0.0 0.2 GO:0035744 T-helper 1 cell cytokine production(GO:0035744)
0.0 0.2 GO:0031022 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473) nuclear migration along microfilament(GO:0031022)
0.0 0.1 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
0.0 0.2 GO:0060677 ureteric bud elongation(GO:0060677)
0.0 0.2 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 2.1 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.3 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.2 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 1.0 GO:0010744 positive regulation of macrophage derived foam cell differentiation(GO:0010744)
0.0 0.7 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.7 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.1 GO:1904580 regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582)
0.0 0.7 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.1 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.0 0.7 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.2 GO:0072299 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.0 0.1 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.0 0.1 GO:0002818 intracellular defense response(GO:0002818)
0.0 0.1 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.0 0.1 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.0 0.3 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.6 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.2 GO:0034436 glycoprotein transport(GO:0034436)
0.0 0.1 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.1 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.0 0.3 GO:1904252 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.0 0.2 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 0.6 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.3 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.2 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.3 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.8 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.2 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.3 GO:0003360 brainstem development(GO:0003360)
0.0 0.3 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.1 GO:0021569 rhombomere 3 development(GO:0021569)
0.0 0.3 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.2 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.0 0.4 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.0 0.4 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.0 0.2 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 0.2 GO:1990262 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.0 0.1 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 0.1 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.0 0.3 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.1 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.4 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.0 0.3 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.1 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 1.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.2 GO:0002158 osteoclast proliferation(GO:0002158)
0.0 0.1 GO:0001189 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.0 0.1 GO:0061047 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) positive regulation of branching involved in lung morphogenesis(GO:0061047) canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.0 0.2 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
0.0 0.4 GO:0071313 cellular response to caffeine(GO:0071313)
0.0 0.1 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 0.4 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.2 GO:0003183 mitral valve morphogenesis(GO:0003183)
0.0 0.4 GO:0032740 positive regulation of interleukin-17 production(GO:0032740)
0.0 0.4 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.3 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.0 0.8 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.7 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.1 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.3 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.1 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
0.0 0.2 GO:0071830 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0 0.1 GO:0035548 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.0 0.1 GO:0015766 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 0.1 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.0 0.3 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.4 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 0.0 GO:1902567 negative regulation of eosinophil activation(GO:1902567)
0.0 0.2 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.0 0.2 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.0 0.4 GO:0032196 transposition(GO:0032196)
0.0 0.2 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.0 0.1 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.3 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.2 GO:0097012 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.1 GO:1903975 regulation of glial cell migration(GO:1903975)
0.0 0.1 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.6 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.2 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.2 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.1 GO:0051792 short-chain fatty acid biosynthetic process(GO:0051790) medium-chain fatty acid biosynthetic process(GO:0051792)
0.0 0.4 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.1 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.0 0.4 GO:0090009 primitive streak formation(GO:0090009)
0.0 0.1 GO:0071105 response to interleukin-11(GO:0071105)
0.0 0.1 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.7 GO:0001945 lymph vessel development(GO:0001945)
0.0 0.2 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.4 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 2.6 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.0 0.1 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.0 0.1 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 0.1 GO:0060763 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721) mammary duct terminal end bud growth(GO:0060763)
0.0 0.1 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.0 1.1 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 1.1 GO:0010107 potassium ion import(GO:0010107)
0.0 0.4 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.0 0.1 GO:0070272 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.8 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.5 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.0 GO:0030222 eosinophil differentiation(GO:0030222)
0.0 0.1 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0 0.3 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.2 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.2 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.3 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.1 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.5 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0 0.1 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.1 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:0018032 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.0 0.1 GO:0070889 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) platelet alpha granule organization(GO:0070889) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.1 GO:0060454 positive regulation of gastric acid secretion(GO:0060454)
0.0 0.2 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722) regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:1990523 bone regeneration(GO:1990523)
0.0 0.1 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.0 0.2 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.3 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.2 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.1 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.3 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.2 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.3 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.3 GO:0060134 prepulse inhibition(GO:0060134)
0.0 0.2 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.0 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.0 0.2 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.1 GO:0035934 corticosterone secretion(GO:0035934)
0.0 0.1 GO:0015692 lead ion transport(GO:0015692)
0.0 0.1 GO:0030432 peristalsis(GO:0030432) somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0 1.0 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.2 GO:0051024 positive regulation of immunoglobulin secretion(GO:0051024)
0.0 0.1 GO:1903906 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0 0.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 0.2 GO:0001696 gastric acid secretion(GO:0001696)
0.0 0.5 GO:0021591 ventricular system development(GO:0021591)
0.0 0.5 GO:0032801 receptor catabolic process(GO:0032801)
0.0 0.4 GO:0060561 apoptotic process involved in morphogenesis(GO:0060561)
0.0 0.1 GO:0061042 vascular wound healing(GO:0061042)
0.0 0.4 GO:0032098 regulation of appetite(GO:0032098)
0.0 0.0 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.1 GO:0042711 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0 0.4 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.2 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.1 GO:1902571 regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.1 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.2 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.2 GO:1903350 response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
0.0 0.0 GO:0036451 cap mRNA methylation(GO:0036451)
0.0 0.3 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.2 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.1 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.1 GO:0006710 androgen catabolic process(GO:0006710)
0.0 1.3 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.0 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.0 1.0 GO:0030317 sperm motility(GO:0030317)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.4 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.2 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.0 0.2 GO:0021930 cell proliferation in hindbrain(GO:0021534) cell proliferation in external granule layer(GO:0021924) cerebellar granule cell precursor proliferation(GO:0021930)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 1.2 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.3 GO:0007616 long-term memory(GO:0007616)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.1 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0007501 mesodermal cell fate specification(GO:0007501)
0.0 0.1 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.1 GO:0007512 adult heart development(GO:0007512)
0.0 0.6 GO:0007566 embryo implantation(GO:0007566)
0.0 0.0 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.2 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.1 GO:1902913 positive regulation of melanocyte differentiation(GO:0045636) positive regulation of neuroepithelial cell differentiation(GO:1902913)
0.0 0.3 GO:1903859 regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.4 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.2 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.6 GO:0008088 axo-dendritic transport(GO:0008088)
0.0 0.5 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.0 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.2 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.2 0.7 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.2 0.7 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.2 0.6 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.1 3.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.4 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.7 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.1 0.4 GO:1990356 sumoylated E2 ligase complex(GO:1990356)
0.1 0.4 GO:1990425 ryanodine receptor complex(GO:1990425)
0.1 0.3 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.1 0.4 GO:1990393 3M complex(GO:1990393)
0.1 0.7 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 1.1 GO:0032426 stereocilium tip(GO:0032426)
0.1 1.0 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.3 GO:1990761 growth cone lamellipodium(GO:1990761)
0.1 0.2 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 0.2 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 0.9 GO:0033010 paranodal junction(GO:0033010)
0.0 0.4 GO:0032010 phagolysosome(GO:0032010)
0.0 0.4 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.8 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.8 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.2 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 1.0 GO:0000786 nucleosome(GO:0000786)
0.0 0.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 1.1 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.4 GO:0001940 male pronucleus(GO:0001940)
0.0 0.2 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.7 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.3 GO:0045298 tubulin complex(GO:0045298)
0.0 0.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.5 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.3 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.5 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.8 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 1.3 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0001652 granular component(GO:0001652)
0.0 0.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.2 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.3 GO:0071546 pi-body(GO:0071546)
0.0 0.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.2 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.3 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.1 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.4 GO:0097512 cardiac myofibril(GO:0097512)
0.0 3.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.3 GO:0032009 early phagosome(GO:0032009)
0.0 0.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.7 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.0 0.5 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.4 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.2 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0097444 spine apparatus(GO:0097444)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.6 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.1 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.6 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.2 GO:0016600 flotillin complex(GO:0016600)
0.0 3.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.4 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.1 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 1.8 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.3 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.7 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 3.4 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 0.1 GO:0061202 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.4 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.2 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.4 1.3 GO:0055100 adiponectin binding(GO:0055100)
0.2 0.7 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.2 0.9 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.2 0.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.2 1.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 0.5 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.1 1.3 GO:0030883 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.1 0.7 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.4 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.1 1.2 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.8 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 0.5 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 1.0 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 1.0 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 0.3 GO:0030305 heparanase activity(GO:0030305)
0.1 0.3 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.1 0.7 GO:0030492 hemoglobin binding(GO:0030492)
0.1 0.6 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1 0.8 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 2.0 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 1.0 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 0.4 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.1 0.5 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.1 0.5 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.1 0.4 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.1 0.3 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.1 1.1 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 0.3 GO:0097604 temperature-gated cation channel activity(GO:0097604)
0.1 0.4 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 1.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 2.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.3 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.1 0.2 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 0.3 GO:0099609 microtubule lateral binding(GO:0099609)
0.1 0.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.4 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.8 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 0.4 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.1 0.4 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 1.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.4 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.2 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 0.3 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.1 0.4 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 0.4 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.1 0.6 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.6 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.4 GO:0044548 S100 protein binding(GO:0044548)
0.1 0.5 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 0.2 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.1 0.2 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.1 1.0 GO:0043295 glutathione binding(GO:0043295)
0.1 0.7 GO:0008517 folic acid transporter activity(GO:0008517)
0.1 0.3 GO:1902444 riboflavin binding(GO:1902444)
0.1 0.4 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.5 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.9 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 1.0 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.3 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.2 GO:0032089 NACHT domain binding(GO:0032089)
0.0 0.2 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.4 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.4 GO:0034711 inhibin binding(GO:0034711)
0.0 0.3 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.1 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.0 0.2 GO:0004803 transposase activity(GO:0004803)
0.0 2.8 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.2 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 2.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.4 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.4 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.3 GO:0042835 BRE binding(GO:0042835)
0.0 1.2 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.4 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.2 GO:0097108 hedgehog family protein binding(GO:0097108)
0.0 0.9 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.3 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.0 0.2 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0 0.3 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.1 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.0 0.3 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 1.2 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.1 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.0 0.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 1.0 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.6 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.3 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.5 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.5 GO:0019864 IgG binding(GO:0019864)
0.0 1.1 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.2 GO:0005330 dopamine:sodium symporter activity(GO:0005330)
0.0 0.7 GO:0048156 tau protein binding(GO:0048156)
0.0 0.2 GO:0051373 FATZ binding(GO:0051373)
0.0 0.7 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.3 GO:0016015 morphogen activity(GO:0016015)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.3 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.2 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.7 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.4 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.2 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.0 0.1 GO:0015154 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 1.4 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 1.5 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.4 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 3.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0033265 choline binding(GO:0033265)
0.0 0.3 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.6 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.5 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.1 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.6 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.1 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 3.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.1 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.0 0.5 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.2 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0 0.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.3 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.2 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.0 0.8 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0001626 nociceptin receptor activity(GO:0001626)
0.0 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 1.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.6 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 1.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 1.3 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.0 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.1 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.2 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.1 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 0.1 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.0 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.1 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.0 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.1 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0 0.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.0 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.1 GO:0035925 C-C chemokine binding(GO:0019957) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 0.2 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 2.2 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 3.2 PID LKB1 PATHWAY LKB1 signaling events
0.0 2.8 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.2 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.1 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 1.2 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.2 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.8 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.1 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.5 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.7 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.8 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.6 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 4.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.3 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.3 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 0.1 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.1 0.3 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 2.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 0.8 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 1.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 0.9 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.1 2.0 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 1.1 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.6 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.5 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.4 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 1.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.7 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.5 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.7 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.6 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.7 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.5 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.5 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.8 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.4 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.1 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.9 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.4 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.7 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.2 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 0.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.2 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.1 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 1.2 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)