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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for EVX2

Z-value: 0.26

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Transcription factors associated with EVX2

Gene Symbol Gene ID Gene Info
EVX2
ENSG00000174279.4 EVX2

Activity profile of EVX2 motif

Sorted Z-values of EVX2 motif

Network of associatons between targets according to the STRING database.

Top targets:

Promoter Score Transcript Gene Gene Info
chr3_+_111999326 0.66 ENST00000494932.1
TAGLN3
transgelin 3
chr11_-_115504389 0.66 ENST00000545380.5
ENST00000452722.7
ENST00000331581.11
ENST00000537058.5
ENST00000536727.5
ENST00000542447.6
CADM1
cell adhesion molecule 1
chr3_+_111998915 0.54 ENST00000478951.6
TAGLN3
transgelin 3
chr3_+_111998739 0.54 ENST00000393917.6
ENST00000273368.8
TAGLN3
transgelin 3
chr3_+_111999189 0.53 ENST00000455401.6
TAGLN3
transgelin 3
chr1_+_27934980 0.25 ENST00000373894.8
SMPDL3B
sphingomyelin phosphodiesterase acid like 3B
chr1_+_27935110 0.23 ENST00000549094.1
SMPDL3B
sphingomyelin phosphodiesterase acid like 3B
chr20_-_51802433 0.22 ENST00000395997.3
SALL4
spalt like transcription factor 4
chr5_-_97142579 0.21 ENST00000274382.9
LIX1
limb and CNS expressed 1
chr20_-_51802509 0.18 ENST00000371539.7
ENST00000217086.9
SALL4
spalt like transcription factor 4
chr4_+_143433491 0.14 ENST00000512843.1
GAB1
GRB2 associated binding protein 1
chr4_+_76435216 0.10 ENST00000296043.7
SHROOM3
shroom family member 3
chr4_-_73620629 0.09 ENST00000342081.7
RASSF6
Ras association domain family member 6
chr4_+_112860912 0.09 ENST00000671951.1
ANK2
ankyrin 2
chr4_+_112861053 0.09 ENST00000672221.1
ANK2
ankyrin 2
chr4_+_112860981 0.08 ENST00000671704.1
ANK2
ankyrin 2
chr2_+_71276553 0.08 ENST00000494621.5
ENST00000466975.5
ENST00000410075.5
ENST00000466330.5
ZNF638
zinc finger protein 638
chr4_-_145180496 0.05 ENST00000447906.8
OTUD4
OTU deubiquitinase 4
chr1_-_99766620 0.05 ENST00000646001.2
FRRS1
ferric chelate reductase 1
chr1_+_27935022 0.05 ENST00000411604.5
ENST00000373888.8
SMPDL3B
sphingomyelin phosphodiesterase acid like 3B
chr6_+_39792298 0.04 ENST00000633794.1
ENST00000274867.9
DAAM2
dishevelled associated activator of morphogenesis 2
chr21_-_31160904 0.04 ENST00000636887.1
TIAM1
TIAM Rac1 associated GEF 1
chr12_+_119668109 0.04 ENST00000229328.10
ENST00000630317.1
PRKAB1
protein kinase AMP-activated non-catalytic subunit beta 1
chr20_+_31879798 0.03 ENST00000620043.4
TTLL9
tubulin tyrosine ligase like 9
chr6_-_62286161 0.03 ENST00000281156.5
KHDRBS2
KH RNA binding domain containing, signal transduction associated 2
chr12_-_53336342 0.02 ENST00000537210.2
ENST00000536324.4
SP7
Sp7 transcription factor
chr17_+_18183803 0.01 ENST00000399138.5
ALKBH5
alkB homolog 5, RNA demethylase
chr1_-_151459169 0.01 ENST00000368863.6
ENST00000409503.5
ENST00000491586.5
ENST00000533351.5
POGZ
pogo transposable element derived with ZNF domain
chr12_+_28257195 0.01 ENST00000381259.5
CCDC91
coiled-coil domain containing 91
chrX_-_63755187 0.00 ENST00000635729.1
ENST00000623566.3
ARHGEF9
Cdc42 guanine nucleotide exchange factor 9
chr19_-_46634685 0.00 ENST00000300873.4
GNG8
G protein subunit gamma 8

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.5 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.3 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.4 GO:0001833 inner cell mass cell proliferation(GO:0001833)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions