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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for FIGLA

Z-value: 0.87

Motif logo

Transcription factors associated with FIGLA

Gene Symbol Gene ID Gene Info
ENSG00000183733.6 FIGLA

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FIGLAhg38_v1_chr2_-_70790643_707906430.319.6e-02Click!

Activity profile of FIGLA motif

Sorted Z-values of FIGLA motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FIGLA

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr6_-_39322688 2.90 ENST00000437525.3
potassium two pore domain channel subfamily K member 16
chr17_+_41105332 2.58 ENST00000391415.1
ENST00000617453.1
keratin associated protein 4-9
chr17_-_41055211 2.23 ENST00000542910.1
ENST00000398477.1
keratin associated protein 2-2
chr17_+_41255384 1.99 ENST00000394008.1
keratin associated protein 9-9
chr17_-_41178219 1.94 ENST00000377726.3
keratin associated protein 4-2
chr11_+_118304881 1.84 ENST00000528600.1
CD3e molecule
chr11_+_118304721 1.83 ENST00000361763.9
CD3e molecule
chr17_-_41149823 1.75 ENST00000343246.6
keratin associated protein 4-5
chr17_-_41124178 1.48 ENST00000394014.2
keratin associated protein 4-12
chr17_-_41047267 1.43 ENST00000542137.1
ENST00000391419.3
keratin associated protein 2-1
chr3_+_49022077 1.42 ENST00000326925.11
NADH:ubiquinone oxidoreductase complex assembly factor 3
chr3_+_49021605 1.36 ENST00000451378.2
NADH:ubiquinone oxidoreductase complex assembly factor 3
chr20_+_45812632 1.16 ENST00000335046.7
ENST00000356455.9
ENST00000243893.10
ubiquitin conjugating enzyme E2 C
chr20_+_45812665 1.14 ENST00000352551.9
ubiquitin conjugating enzyme E2 C
chr20_+_45812576 1.14 ENST00000405520.5
ENST00000617055.4
ubiquitin conjugating enzyme E2 C
chr17_+_41226648 1.08 ENST00000377721.3
keratin associated protein 9-2
chr11_-_123654939 1.07 ENST00000657191.1
sodium voltage-gated channel beta subunit 3
chr17_+_41237998 1.04 ENST00000254072.7
keratin associated protein 9-8
chr19_-_50952942 1.00 ENST00000594846.1
ENST00000336334.8
kallikrein related peptidase 5
chr17_-_41160746 0.98 ENST00000390661.5
keratin associated protein 4-4
chr6_+_96015964 0.98 ENST00000302103.6
fucosyltransferase 9
chr11_-_123654581 0.91 ENST00000392770.6
ENST00000530277.5
ENST00000299333.8
sodium voltage-gated channel beta subunit 3
chr17_+_50056095 0.85 ENST00000320031.13
integrin subunit alpha 3
chr11_-_35419098 0.85 ENST00000606205.6
ENST00000645303.1
solute carrier family 1 member 2
chr11_-_35419462 0.83 ENST00000643522.1
solute carrier family 1 member 2
chr11_-_35419213 0.82 ENST00000642171.1
ENST00000644050.1
ENST00000643134.1
solute carrier family 1 member 2
chr11_-_35418966 0.81 ENST00000531628.2
solute carrier family 1 member 2
chrX_-_30308333 0.80 ENST00000378963.1
nuclear receptor subfamily 0 group B member 1
chr12_-_129904017 0.77 ENST00000422113.7
transmembrane protein 132D
chr5_+_69167216 0.75 ENST00000508407.5
ENST00000505500.5
cyclin B1
chr8_+_32548303 0.74 ENST00000650967.1
neuregulin 1
chr8_+_32548210 0.70 ENST00000523079.5
ENST00000650919.1
neuregulin 1
chr11_+_60455839 0.64 ENST00000532491.5
ENST00000532073.5
ENST00000345732.9
ENST00000534668.6
ENST00000528313.1
ENST00000533306.6
ENST00000674194.1
membrane spanning 4-domains A1
chr12_-_117968972 0.61 ENST00000339824.7
kinase suppressor of ras 2
chr4_+_127730386 0.57 ENST00000281154.6
solute carrier family 25 member 31
chr6_-_37258110 0.56 ENST00000357219.4
ENST00000652386.1
ENST00000652639.1
transmembrane protein 217
chr2_-_174764407 0.56 ENST00000409219.5
ENST00000409542.5
cholinergic receptor nicotinic alpha 1 subunit
chr7_-_100100716 0.53 ENST00000354230.7
ENST00000425308.5
minichromosome maintenance complex component 7
chr1_+_21977014 0.50 ENST00000337107.11
chymotrypsin like elastase 3B
chr15_+_88638947 0.49 ENST00000559876.2
interferon stimulated exonuclease gene 20
chr11_+_119087979 0.48 ENST00000535253.5
ENST00000392841.1
ENST00000648374.1
hydroxymethylbilane synthase
chr2_-_2326378 0.47 ENST00000647618.1
myelin transcription factor 1 like
chr16_+_87602478 0.45 ENST00000284262.3
junctophilin 3
chr1_+_6555301 0.44 ENST00000333172.11
ENST00000351136.7
taste 1 receptor member 1
chr15_+_45430579 0.43 ENST00000558435.5
ENST00000344300.3
ENST00000396650.7
chromosome 15 open reading frame 48
chr7_+_120273129 0.43 ENST00000331113.9
potassium voltage-gated channel subfamily D member 2
chr5_-_160312756 0.43 ENST00000644313.1
cyclin J like
chrX_-_154014246 0.43 ENST00000444254.1
interleukin 1 receptor associated kinase 1
chr12_-_117968223 0.42 ENST00000425217.5
kinase suppressor of ras 2
chr17_+_8339837 0.42 ENST00000328248.7
ENST00000584943.1
outer dense fiber of sperm tails 4
chr1_+_183186238 0.42 ENST00000493293.5
ENST00000264144.5
laminin subunit gamma 2
chr11_+_66011994 0.42 ENST00000312134.3
cystatin E/M
chr17_+_9645502 0.42 ENST00000285199.12
ubiquitin specific peptidase 43
chr5_-_160312524 0.42 ENST00000520748.1
ENST00000257536.13
ENST00000393977.7
cyclin J like
chr6_+_41921491 0.41 ENST00000230340.9
bystin like
chr7_+_18496231 0.41 ENST00000401921.5
histone deacetylase 9
chrX_-_138711663 0.40 ENST00000315930.11
fibroblast growth factor 13
chr4_-_138242325 0.40 ENST00000280612.9
solute carrier family 7 member 11
chr11_+_71453189 0.40 ENST00000319023.7
NAD synthetase 1
chr17_+_41249687 0.40 ENST00000334109.3
keratin associated protein 9-4
chrX_+_111096211 0.39 ENST00000372010.5
ENST00000519681.5
p21 (RAC1) activated kinase 3
chr7_-_100101333 0.39 ENST00000303887.10
minichromosome maintenance complex component 7
chr11_-_84923162 0.39 ENST00000524982.5
discs large MAGUK scaffold protein 2
chr4_-_21948733 0.39 ENST00000447367.6
ENST00000382152.7
potassium voltage-gated channel interacting protein 4
chr15_+_88639009 0.39 ENST00000306072.10
interferon stimulated exonuclease gene 20
chr3_+_172750682 0.38 ENST00000232458.9
ENST00000540509.5
epithelial cell transforming 2
chr11_-_84923403 0.38 ENST00000532653.5
discs large MAGUK scaffold protein 2
chr1_+_21981099 0.38 ENST00000400277.2
chymotrypsin like elastase 3B
chr3_+_172750715 0.38 ENST00000392692.8
ENST00000417960.5
ENST00000428567.5
ENST00000366090.6
ENST00000426894.5
epithelial cell transforming 2
chr16_+_6483379 0.37 ENST00000552089.5
RNA binding fox-1 homolog 1
chr2_-_174764436 0.37 ENST00000409323.1
ENST00000261007.9
ENST00000348749.9
ENST00000672640.1
cholinergic receptor nicotinic alpha 1 subunit
chr1_-_16978276 0.37 ENST00000375534.7
microfibril associated protein 2
chr8_-_144358458 0.35 ENST00000331890.6
ENST00000455319.6
F-box and leucine rich repeat protein 6
chr7_+_2647703 0.35 ENST00000403167.5
tweety family member 3
chr8_-_92017292 0.35 ENST00000521553.5
RUNX1 partner transcriptional co-repressor 1
chr15_+_90184912 0.35 ENST00000561085.1
ENST00000332496.10
semaphorin 4B
chr1_-_11060000 0.34 ENST00000376957.7
spermidine synthase
chr6_+_44216914 0.34 ENST00000573382.3
ENST00000576476.1
myomixer, myoblast fusion factor
chr7_-_130687432 0.34 ENST00000456951.5
testis specific 13
chr8_+_32548267 0.34 ENST00000356819.7
neuregulin 1
chr12_+_47963557 0.34 ENST00000256686.10
ENST00000549288.5
ENST00000429772.7
ENST00000552561.5
ENST00000546749.5
ENST00000552546.5
ENST00000550552.5
transmembrane protein 106C
chr9_+_133061981 0.32 ENST00000372080.8
carboxyl ester lipase
chr3_-_50322733 0.32 ENST00000428028.1
ENST00000357750.9
hyaluronidase 2
chr3_-_50322759 0.32 ENST00000442581.1
ENST00000447092.5
hyaluronidase 2
chr17_-_41098084 0.32 ENST00000318329.6
ENST00000333822.5
keratin associated protein 4-8
chr6_+_108848387 0.32 ENST00000368972.7
ENST00000392644.9
armadillo repeat containing 2
chr17_-_35089212 0.32 ENST00000584655.5
ENST00000447669.6
ENST00000315249.11
ring finger and FYVE like domain containing E3 ubiquitin protein ligase
chr2_+_37344594 0.31 ENST00000404976.5
ENST00000338415.8
glutaminyl-peptide cyclotransferase
chr15_+_59438149 0.31 ENST00000288228.10
ENST00000559628.5
ENST00000557914.5
ENST00000560474.5
family with sequence similarity 81 member A
chr17_+_81528370 0.31 ENST00000417245.7
ENST00000334850.7
fascin actin-bundling protein 2, retinal
chr12_-_52192007 0.30 ENST00000394815.3
keratin 80
chr22_+_49918626 0.30 ENST00000328268.9
ENST00000404488.7
cysteine rich with EGF like domains 2
chr1_-_28643005 0.30 ENST00000263974.4
ENST00000373824.9
ENST00000495422.2
TATA-box binding protein associated factor 12
chr2_+_135531460 0.30 ENST00000683871.1
ENST00000409478.5
ENST00000264160.8
ENST00000438014.5
R3H domain containing 1
chr7_-_11832190 0.29 ENST00000423059.9
ENST00000617773.1
thrombospondin type 1 domain containing 7A
chr16_+_6483728 0.29 ENST00000675459.1
ENST00000551752.5
RNA binding fox-1 homolog 1
chr3_+_35679614 0.29 ENST00000474696.5
ENST00000412048.5
ENST00000396482.6
ENST00000432682.5
cAMP regulated phosphoprotein 21
chr20_-_22585451 0.29 ENST00000377115.4
forkhead box A2
chr16_-_46831043 0.28 ENST00000565112.1
chromosome 16 open reading frame 87
chr19_-_15479469 0.28 ENST00000292609.8
ENST00000340880.5
peptidoglycan recognition protein 2
chr7_-_44189428 0.28 ENST00000673284.1
ENST00000403799.8
ENST00000671824.1
glucokinase
chr7_+_18495723 0.28 ENST00000681950.1
ENST00000622668.4
ENST00000405010.7
ENST00000406451.8
ENST00000441542.7
ENST00000428307.6
ENST00000681273.1
histone deacetylase 9
chr3_-_49929800 0.28 ENST00000455683.6
MON1 homolog A, secretory trafficking associated
chr3_-_48556785 0.28 ENST00000232375.8
ENST00000383734.6
ENST00000416568.5
ENST00000412035.5
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr4_-_89836213 0.28 ENST00000618500.4
ENST00000508895.5
synuclein alpha
chr5_+_6448832 0.27 ENST00000399816.4
ubiquitin conjugating enzyme E2 Q family like 1
chr7_+_18496162 0.27 ENST00000406072.5
histone deacetylase 9
chr12_-_52191981 0.27 ENST00000313234.9
keratin 80
chr5_+_69492767 0.27 ENST00000681041.1
ENST00000680098.1
ENST00000680784.1
ENST00000396442.7
ENST00000681895.1
occludin
chr7_-_151210488 0.27 ENST00000644661.2
H2B.E variant histone 1
chr8_-_48921419 0.27 ENST00000020945.4
snail family transcriptional repressor 2
chr5_+_141489150 0.27 ENST00000610789.1
protocadherin gamma subfamily C, 5
chr22_+_20917398 0.27 ENST00000354336.8
CRK like proto-oncogene, adaptor protein
chr11_+_44726811 0.26 ENST00000533202.5
ENST00000520358.7
ENST00000533080.5
ENST00000520999.6
tetraspanin 18
chrX_+_151694967 0.26 ENST00000448726.5
ENST00000538575.5
proline rich and Gla domain 3
chr7_-_78771265 0.26 ENST00000630991.2
ENST00000629359.2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr1_-_53142577 0.26 ENST00000620347.5
ENST00000611397.5
solute carrier family 1 member 7
chr1_+_10450004 0.26 ENST00000377049.4
cortistatin
chr6_-_39322540 0.26 ENST00000425054.6
ENST00000373227.8
ENST00000373229.9
potassium two pore domain channel subfamily K member 16
chr7_+_129144691 0.25 ENST00000486685.3
tetraspanin 33
chr2_-_24360445 0.25 ENST00000443927.5
ENST00000406921.7
ENST00000412011.5
ENST00000355123.9
intersectin 2
chr16_+_6483813 0.25 ENST00000675653.1
RNA binding fox-1 homolog 1
chr15_+_83107572 0.25 ENST00000379390.10
ENST00000322019.14
ENST00000565774.5
ENST00000565982.1
transmembrane 6 superfamily member 1
chr17_-_41168219 0.25 ENST00000391356.4
keratin associated protein 4-3
chr4_+_6269869 0.25 ENST00000506362.2
wolframin ER transmembrane glycoprotein
chr1_-_53142617 0.25 ENST00000371491.4
ENST00000371494.9
solute carrier family 1 member 7
chr5_-_54985579 0.25 ENST00000381405.5
ENST00000381403.4
endothelial cell specific molecule 1
chr5_+_142771119 0.25 ENST00000642734.1
Rho GTPase activating protein 26
chr2_-_75560893 0.25 ENST00000410113.5
ENST00000393913.8
eva-1 homolog A, regulator of programmed cell death
chr2_-_162152404 0.25 ENST00000375497.3
glucagon
chr2_+_169733811 0.25 ENST00000392647.7
kelch like family member 23
chr15_+_53978410 0.24 ENST00000260323.16
unc-13 homolog C
chr19_+_35856885 0.24 ENST00000347900.10
ENST00000360202.10
kirre like nephrin family adhesion molecule 2
chr15_+_53978201 0.24 ENST00000647821.1
unc-13 homolog C
chr6_+_46793379 0.24 ENST00000230588.9
ENST00000611727.2
meprin A subunit alpha
chr2_-_162152239 0.24 ENST00000418842.7
glucagon
chr4_+_6269831 0.24 ENST00000503569.5
ENST00000673991.1
ENST00000682275.1
ENST00000226760.5
wolframin ER transmembrane glycoprotein
chr2_+_135586250 0.23 ENST00000410054.5
ENST00000628915.2
R3H domain containing 1
chr19_-_50514624 0.23 ENST00000601207.5
ENST00000598657.1
ENST00000376916.7
aspartate dehydrogenase domain containing
chr3_-_167474026 0.23 ENST00000466903.1
ENST00000264677.8
serpin family I member 2
chr17_-_31297231 0.22 ENST00000247271.5
oligodendrocyte myelin glycoprotein
chr17_-_36534841 0.22 ENST00000614623.5
ENST00000621344.4
myosin XIX
chr8_-_28490220 0.22 ENST00000517673.5
ENST00000380254.7
ENST00000518734.5
ENST00000346498.6
F-box protein 16
chr1_-_156705742 0.22 ENST00000368221.1
cellular retinoic acid binding protein 2
chr16_+_4795357 0.22 ENST00000586005.6
small integral membrane protein 22
chrX_+_71223216 0.22 ENST00000361726.7
gap junction protein beta 1
chr16_+_29995661 0.22 ENST00000304516.11
INO80 complex subunit E
chr16_+_4795378 0.22 ENST00000588606.5
small integral membrane protein 22
chr11_-_88337722 0.21 ENST00000677976.1
ENST00000528020.2
ENST00000393301.5
ENST00000529974.2
ENST00000227266.10
ENST00000678464.1
ENST00000679199.1
ENST00000527018.6
ENST00000679224.1
ENST00000678506.1
ENST00000678915.1
ENST00000524463.6
cathepsin C
chr1_-_24415035 0.21 ENST00000374409.5
sperm tail PG-rich repeat containing 1
chr19_+_53882186 0.20 ENST00000682028.1
ENST00000683513.1
ENST00000263431.4
ENST00000419486.1
protein kinase C gamma
chr15_-_34336749 0.20 ENST00000397707.6
ENST00000560611.5
solute carrier family 12 member 6
chr7_-_85187039 0.20 ENST00000284136.11
semaphorin 3D
chr16_-_75536071 0.20 ENST00000336257.8
carbohydrate sulfotransferase 5
chr2_+_64454145 0.19 ENST00000238875.10
galectin like
chr6_+_150683593 0.19 ENST00000644968.1
pleckstrin homology and RhoGEF domain containing G1
chr22_-_18518161 0.19 ENST00000619998.1
gamma-glutamyltransferase light chain family member 3
chr3_+_184230373 0.19 ENST00000426955.6
von Willebrand factor A domain containing 5B2
chr3_+_68006224 0.19 ENST00000496687.1
TAFA chemokine like family member 1
chr2_+_240435652 0.19 ENST00000264039.7
glypican 1
chr1_-_12616762 0.18 ENST00000464917.5
dehydrogenase/reductase 3
chr14_+_30874541 0.18 ENST00000396618.9
ENST00000644874.2
ENST00000555117.2
ENST00000475087.5
cochlin
chr2_-_223837553 0.18 ENST00000396654.7
ENST00000396653.2
ENST00000443700.5
adaptor related protein complex 1 subunit sigma 3
chr7_+_148339452 0.18 ENST00000463592.3
contactin associated protein 2
chr1_-_156705764 0.18 ENST00000621784.4
ENST00000368220.1
cellular retinoic acid binding protein 2
chr5_+_53560627 0.18 ENST00000296684.10
ENST00000506765.1
NADH:ubiquinone oxidoreductase subunit S4
chr11_+_66857056 0.18 ENST00000309602.5
ENST00000393952.3
leucine rich repeat and fibronectin type III domain containing 4
chr4_-_109729956 0.17 ENST00000502283.1
phospholipase A2 group XIIA
chr1_-_156705575 0.17 ENST00000368222.8
cellular retinoic acid binding protein 2
chr1_-_171652675 0.17 ENST00000037502.11
myocilin
chr14_-_106324743 0.16 ENST00000390612.3
immunoglobulin heavy variable 4-28
chr3_+_50155024 0.16 ENST00000414301.5
ENST00000450338.5
ENST00000413852.5
semaphorin 3F
chr3_+_156674579 0.16 ENST00000295924.12
TCDD inducible poly(ADP-ribose) polymerase
chr1_-_41918858 0.16 ENST00000372583.6
HIVEP zinc finger 3
chr1_-_41918666 0.16 ENST00000372584.5
HIVEP zinc finger 3
chr5_+_83471925 0.16 ENST00000502527.2
versican
chr1_-_243163310 0.16 ENST00000492145.1
ENST00000490813.5
ENST00000464936.5
centrosomal protein 170
chr4_+_183099244 0.16 ENST00000403733.8
WW and C2 domain containing 2
chr16_+_30372291 0.15 ENST00000568749.5
myosin light chain, phosphorylatable, fast skeletal muscle
chr12_-_30754927 0.15 ENST00000541765.5
ENST00000537108.5
caprin family member 2
chr2_-_178807415 0.15 ENST00000342992.10
ENST00000460472.6
ENST00000589042.5
ENST00000591111.5
ENST00000360870.10
titin
chrX_-_154409278 0.15 ENST00000369808.7
deoxyribonuclease 1 like 1
chr17_-_41118369 0.15 ENST00000391413.4
keratin associated protein 4-11
chr5_+_151447576 0.15 ENST00000243389.8
ENST00000616007.4
ENST00000517945.5
ENST00000521925.5
solute carrier family 36 member 1
chr22_-_42720813 0.15 ENST00000381278.4
alpha 1,4-galactosyltransferase (P blood group)
chrX_-_154409246 0.14 ENST00000369807.6
deoxyribonuclease 1 like 1
chr22_+_30694851 0.14 ENST00000332585.11
oxysterol binding protein 2
chr17_+_41084150 0.14 ENST00000391417.5
ENST00000621138.1
keratin associated protein 4-7
chr6_+_17281341 0.14 ENST00000379052.10
RNA binding motif protein 24
chr5_-_16936231 0.14 ENST00000507288.1
ENST00000274203.13
ENST00000513610.6
myosin X
chr17_+_42833390 0.14 ENST00000590720.6
ENST00000586114.5
ENST00000585805.5
ENST00000441946.6
ENST00000591152.5
ENST00000589469.5
ENST00000293362.7
ENST00000592169.2
proteasome activator subunit 3
chr3_+_63911929 0.14 ENST00000487717.5
ataxin 7
chr7_-_149028452 0.14 ENST00000413966.1
ENST00000652332.1
protein disulfide isomerase family A member 4
chr16_-_46831134 0.14 ENST00000394806.6
ENST00000285697.9
chromosome 16 open reading frame 87
chr18_+_57352541 0.13 ENST00000324000.4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr11_+_68312542 0.13 ENST00000294304.12
LDL receptor related protein 5
chr7_-_149028651 0.13 ENST00000286091.9
protein disulfide isomerase family A member 4
chr1_+_178725227 0.13 ENST00000367635.8
Ral GEF with PH domain and SH3 binding motif 2
chr11_-_63144221 0.13 ENST00000417740.5
ENST00000612278.4
ENST00000326192.5
solute carrier family 22 member 24
chr22_+_22811737 0.13 ENST00000390315.3
immunoglobulin lambda variable 3-10

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.7 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.3 3.4 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.3 0.8 GO:0071283 regulation of chromosome condensation(GO:0060623) cellular response to iron(III) ion(GO:0071283)
0.2 2.0 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.2 0.9 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.2 3.2 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.2 1.0 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
0.2 0.5 GO:1903892 negative regulation of ATF6-mediated unfolded protein response(GO:1903892)
0.2 0.5 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.1 1.9 GO:0038129 ERBB3 signaling pathway(GO:0038129)
0.1 0.4 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 0.6 GO:0070295 transformation of host cell by virus(GO:0019087) renal water absorption(GO:0070295)
0.1 0.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.1 0.5 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.1 0.3 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.1 2.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.3 GO:0032824 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.1 0.3 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.1 0.8 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.1 0.2 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.1 0.3 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.1 14.6 GO:0031424 keratinization(GO:0031424)
0.1 0.4 GO:0050917 sensory perception of umami taste(GO:0050917)
0.1 0.9 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.3 GO:0051594 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.1 1.0 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.1 0.3 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.1 0.3 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.9 GO:0034983 peptidyl-lysine deacetylation(GO:0034983) positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 0.8 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.1 0.2 GO:1903770 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.1 0.3 GO:0001575 globoside metabolic process(GO:0001575)
0.1 0.5 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.9 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 0.8 GO:0033327 Leydig cell differentiation(GO:0033327)
0.1 0.4 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.1 0.3 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.1 0.3 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.3 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.2 GO:0030200 proteoglycan catabolic process(GO:0030167) heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.3 GO:0051621 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.0 0.1 GO:0036292 DNA rewinding(GO:0036292)
0.0 0.6 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.2 GO:0032425 positive regulation of mismatch repair(GO:0032425)
0.0 0.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0 0.3 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.2 GO:0071109 superior temporal gyrus development(GO:0071109)
0.0 0.6 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.1 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.2 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.2 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.0 0.2 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.3 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.8 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 2.4 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:0003409 optic cup structural organization(GO:0003409)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.2 GO:0035290 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.0 0.2 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.3 GO:0070673 response to interleukin-18(GO:0070673)
0.0 0.2 GO:0006477 protein sulfation(GO:0006477)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.3 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.0 0.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.3 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.2 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.0 GO:0034031 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034)
0.0 0.4 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.0 GO:0048560 establishment of anatomical structure orientation(GO:0048560)
0.0 0.1 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.0 0.2 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.4 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.0 0.4 GO:0035640 exploration behavior(GO:0035640)
0.0 0.7 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.2 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.1 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.2 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.4 GO:0009435 NAD biosynthetic process(GO:0009435)
0.0 0.2 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.2 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.0 GO:0097360 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.0 0.5 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.2 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.1 GO:0072092 ureteric bud invasion(GO:0072092)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.7 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 0.9 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.2 0.8 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.2 16.1 GO:0045095 keratin filament(GO:0045095)
0.1 1.0 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 0.8 GO:0097149 centralspindlin complex(GO:0097149)
0.1 3.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 4.4 GO:0030673 axolemma(GO:0030673)
0.1 2.0 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.3 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 0.5 GO:0044305 calyx of Held(GO:0044305)
0.1 0.3 GO:0071821 FANCM-MHF complex(GO:0071821)
0.1 0.8 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.9 GO:0042555 MCM complex(GO:0042555)
0.0 0.4 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.4 GO:0043256 laminin complex(GO:0043256)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.1 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.5 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.8 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.6 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 0.2 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.7 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.0 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.0 0.4 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.2 GO:0070187 telosome(GO:0070187)
0.0 0.5 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.6 GO:0001533 cornified envelope(GO:0001533)
0.0 0.8 GO:0015030 Cajal body(GO:0015030)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.1 GO:0098839 postsynaptic density membrane(GO:0098839)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0008859 exoribonuclease II activity(GO:0008859)
0.3 3.7 GO:0042608 T cell receptor binding(GO:0042608)
0.2 3.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.2 2.0 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.2 0.5 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.1 0.6 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.1 0.8 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 0.3 GO:0004766 spermidine synthase activity(GO:0004766)
0.1 2.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 1.8 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 1.0 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1 0.4 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1 0.3 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.1 3.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 0.4 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.5 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1 0.4 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.2 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.1 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.4 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.3 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.3 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.1 GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
0.0 0.9 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.4 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.3 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.7 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.6 GO:0019841 retinol binding(GO:0019841)
0.0 0.2 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.8 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 1.0 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.1 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.8 GO:0000217 DNA secondary structure binding(GO:0000217)
0.0 0.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.6 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.3 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.3 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.0 0.9 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.4 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.4 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.2 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.0 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.2 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.2 GO:0031433 telethonin binding(GO:0031433)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.5 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.8 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.5 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.0 PID ATR PATHWAY ATR signaling pathway
0.0 1.1 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.9 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 3.7 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 4.3 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.1 0.9 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 1.8 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 2.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 4.3 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.4 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.9 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.9 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.6 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.5 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.3 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS