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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for FLI1

Z-value: 0.50

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Transcription factors associated with FLI1

Gene Symbol Gene ID Gene Info
ENSG00000151702.17 FLI1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FLI1hg38_v1_chr11_+_128694052_128694108,
hg38_v1_chr11_+_128693887_128693931
0.106.1e-01Click!

Activity profile of FLI1 motif

Sorted Z-values of FLI1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FLI1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_+_156815633 0.88 ENST00000392302.7
ENST00000674537.1
neurotrophic receptor tyrosine kinase 1
chr17_-_45432916 0.81 ENST00000290470.3
Rho GTPase activating protein 27
chrY_+_2841864 0.70 ENST00000430575.1
ribosomal protein S4 Y-linked 1
chr19_-_11577632 0.69 ENST00000590420.1
ENST00000648477.1
acid phosphatase 5, tartrate resistant
chr6_+_151239951 0.69 ENST00000402676.7
A-kinase anchoring protein 12
chr15_+_40161003 0.67 ENST00000412359.7
ENST00000287598.11
BUB1 mitotic checkpoint serine/threonine kinase B
chr5_+_892844 0.64 ENST00000166345.8
thyroid hormone receptor interactor 13
chr1_-_205449924 0.64 ENST00000367154.5
LEM domain containing 1
chr14_+_54567100 0.61 ENST00000554335.6
sterile alpha motif domain containing 4A
chr5_-_151686908 0.59 ENST00000231061.9
secreted protein acidic and cysteine rich
chr14_+_54567612 0.58 ENST00000251091.9
ENST00000392067.7
ENST00000631086.2
sterile alpha motif domain containing 4A
chr2_+_218607861 0.56 ENST00000450993.7
phospholipase C delta 4
chr14_-_93976550 0.56 ENST00000555019.6
ankyrin repeat and SOCS box containing 2
chr1_-_159954213 0.54 ENST00000368092.7
ENST00000368093.4
SLAM family member 9
chr16_+_50266530 0.53 ENST00000566433.6
ENST00000394697.7
ENST00000673801.1
adenylate cyclase 7
chr17_-_5234801 0.53 ENST00000571800.5
ENST00000574081.6
ENST00000399600.8
ENST00000574297.1
SLP adaptor and CSK interacting membrane protein
chr16_+_1706163 0.53 ENST00000250894.8
ENST00000673691.1
ENST00000356010.9
ENST00000610761.2
mitogen-activated protein kinase 8 interacting protein 3
chr4_+_2812259 0.51 ENST00000502260.5
ENST00000435136.8
SH3 domain binding protein 2
chrY_+_2841594 0.51 ENST00000250784.13
ribosomal protein S4 Y-linked 1
chr1_-_109283175 0.51 ENST00000409138.6
proline and serine rich coiled-coil 1
chr1_-_109283129 0.50 ENST00000369907.7
ENST00000369909.6
proline and serine rich coiled-coil 1
chr1_-_109283097 0.50 ENST00000369904.7
ENST00000369903.6
ENST00000429031.5
ENST00000418914.2
ENST00000409267.5
proline and serine rich coiled-coil 1
chr3_+_122077850 0.48 ENST00000482356.5
ENST00000393627.6
CD86 molecule
chr7_+_101127095 0.48 ENST00000223095.5
serpin family E member 1
chr9_-_120877026 0.48 ENST00000436309.5
PHD finger protein 19
chr18_+_63752935 0.48 ENST00000425392.5
ENST00000336429.6
serpin family B member 7
chr3_-_28348629 0.47 ENST00000334100.10
5-azacytidine induced 2
chrX_+_136148440 0.46 ENST00000627383.2
ENST00000630084.2
four and a half LIM domains 1
chr9_-_120876356 0.46 ENST00000456291.1
PHD finger protein 19
chr8_-_124565699 0.46 ENST00000519168.5
MTSS I-BAR domain containing 1
chr3_-_28348924 0.46 ENST00000414162.5
ENST00000420543.6
5-azacytidine induced 2
chr3_+_122077776 0.45 ENST00000264468.9
CD86 molecule
chr4_+_185396834 0.45 ENST00000335174.6
ankyrin repeat domain 37
chr1_+_209686173 0.44 ENST00000615289.4
ENST00000367028.6
ENST00000261465.5
hydroxysteroid 11-beta dehydrogenase 1
chr20_+_31739260 0.44 ENST00000340513.4
ENST00000300403.11
TPX2 microtubule nucleation factor
chr1_-_153094521 0.44 ENST00000368750.8
small proline rich protein 2E
chr2_+_233060295 0.44 ENST00000445964.6
inositol polyphosphate-5-phosphatase D
chr5_+_138465472 0.43 ENST00000239938.5
early growth response 1
chr1_+_150508074 0.43 ENST00000369049.8
extracellular matrix protein 1
chr1_+_44746401 0.43 ENST00000372217.5
kinesin family member 2C
chr2_+_233059838 0.43 ENST00000359570.9
inositol polyphosphate-5-phosphatase D
chr12_+_107318395 0.42 ENST00000420571.6
ENST00000280758.10
BTB domain containing 11
chr1_+_150508099 0.42 ENST00000346569.6
ENST00000369047.9
extracellular matrix protein 1
chr1_+_84144260 0.42 ENST00000370685.7
protein kinase cAMP-activated catalytic subunit beta
chr5_-_115626161 0.42 ENST00000282382.8
TMED7-TICAM2 readthrough
chr1_+_3454657 0.41 ENST00000378378.9
Rho guanine nucleotide exchange factor 16
chrX_+_70290077 0.40 ENST00000374403.4
kinesin family member 4A
chr7_+_2242207 0.40 ENST00000356714.6
nudix hydrolase 1
chr19_+_58183029 0.40 ENST00000424679.6
ENST00000617501.5
ENST00000345813.7
zinc finger protein 274
chr6_-_131063233 0.40 ENST00000392427.7
ENST00000337057.8
ENST00000525271.5
ENST00000527411.5
erythrocyte membrane protein band 4.1 like 2
chr18_-_35497591 0.39 ENST00000589273.1
ENST00000586489.5
INO80 complex subunit C
chr19_+_1077394 0.39 ENST00000590577.2
Rho GTPase activating protein 45
chr1_+_156893678 0.39 ENST00000292357.8
ENST00000338302.7
ENST00000455314.5
platelet endothelial aggregation receptor 1
chr7_+_2242256 0.39 ENST00000397046.5
ENST00000397048.5
ENST00000454650.1
nudix hydrolase 1
chr16_-_3099228 0.39 ENST00000572431.1
ENST00000572548.1
ENST00000575108.5
ENST00000576985.6
ENST00000576483.1
ENST00000538082.5
zinc finger and SCAN domain containing 10
chr6_-_131063207 0.39 ENST00000530481.5
erythrocyte membrane protein band 4.1 like 2
chr1_+_154327737 0.38 ENST00000672630.1
ATPase phospholipid transporting 8B2
chr6_-_131063272 0.38 ENST00000445890.6
ENST00000368128.6
ENST00000628542.2
erythrocyte membrane protein band 4.1 like 2
chr10_+_100347225 0.38 ENST00000370355.3
stearoyl-CoA desaturase
chr11_-_10693955 0.38 ENST00000547195.5
inositol 1,4,5-triphosphate receptor associated 1
chr6_-_11382247 0.38 ENST00000397378.7
ENST00000513989.5
ENST00000508546.5
ENST00000504387.5
neural precursor cell expressed, developmentally down-regulated 9
chr1_-_204166334 0.37 ENST00000272190.9
renin
chr12_+_51238854 0.37 ENST00000549732.6
ENST00000604900.5
DAZ associated protein 2
chr2_+_31234144 0.37 ENST00000322054.10
EH domain containing 3
chr22_-_37484505 0.37 ENST00000442496.1
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr2_+_157257687 0.36 ENST00000259056.5
polypeptide N-acetylgalactosaminyltransferase 5
chr5_-_139482714 0.36 ENST00000652543.1
stimulator of interferon response cGAMP interactor 1
chr20_+_44355692 0.36 ENST00000316673.8
ENST00000609795.5
ENST00000457232.5
ENST00000609262.5
hepatocyte nuclear factor 4 alpha
chr12_+_71664352 0.36 ENST00000547843.1
THAP domain containing 2
chr22_-_37519349 0.36 ENST00000251973.10
caspase recruitment domain family member 10
chr19_-_51065067 0.36 ENST00000595547.5
ENST00000335422.3
ENST00000595793.6
ENST00000596955.1
kallikrein related peptidase 13
chr17_+_4433904 0.35 ENST00000355530.7
sphingolipid transporter 3 (putative)
chr22_-_37519528 0.35 ENST00000403299.5
caspase recruitment domain family member 10
chr12_-_13095664 0.35 ENST00000337630.10
ENST00000545699.1
germ cell associated 1
chr1_-_153057504 0.35 ENST00000392653.3
small proline rich protein 2A
chrX_+_15500800 0.34 ENST00000348343.11
BMX non-receptor tyrosine kinase
chr12_-_6631632 0.34 ENST00000431922.1
lysophosphatidic acid receptor 5
chr7_-_1556194 0.34 ENST00000297477.10
transmembrane protein 184A
chr11_+_47248924 0.34 ENST00000481889.6
ENST00000436778.5
ENST00000531660.5
ENST00000407404.5
nuclear receptor subfamily 1 group H member 3
chr2_+_108378176 0.34 ENST00000409309.3
sulfotransferase family 1C member 4
chr4_-_152679984 0.34 ENST00000304385.8
ENST00000504064.1
transmembrane protein 154
chr6_-_42451910 0.34 ENST00000372922.8
ENST00000541110.5
transcriptional regulating factor 1
chr4_+_8199363 0.34 ENST00000382521.7
ENST00000457650.7
SH3 domain and tetratricopeptide repeats 1
chr4_+_8199239 0.34 ENST00000245105.8
SH3 domain and tetratricopeptide repeats 1
chr3_-_28348805 0.34 ENST00000457172.5
ENST00000479665.6
5-azacytidine induced 2
chr5_-_139482741 0.34 ENST00000330794.9
stimulator of interferon response cGAMP interactor 1
chr11_+_47248885 0.34 ENST00000395397.7
ENST00000405576.5
nuclear receptor subfamily 1 group H member 3
chr5_-_139482685 0.33 ENST00000651565.1
stimulator of interferon response cGAMP interactor 1
chr10_-_96271553 0.33 ENST00000224337.10
B cell linker
chr17_-_40937641 0.33 ENST00000209718.8
keratin 23
chr5_-_139482341 0.33 ENST00000651699.1
stimulator of interferon response cGAMP interactor 1
chr12_+_93677352 0.33 ENST00000552983.5
ENST00000332896.8
ENST00000552033.5
ENST00000548483.5
CASP2 and RIPK1 domain containing adaptor with death domain
chr19_-_52171643 0.32 ENST00000597065.1
zinc finger protein 836
chr2_+_24076817 0.32 ENST00000613899.4
family with sequence similarity 228 member B
chr17_-_40937445 0.32 ENST00000436344.7
ENST00000485751.1
keratin 23
chr14_-_100376251 0.32 ENST00000556645.5
ENST00000556209.5
ENST00000556504.5
ENST00000556435.5
ENST00000554772.5
ENST00000553581.1
ENST00000553769.6
ENST00000554605.5
ENST00000557722.5
ENST00000553413.5
ENST00000553524.5
ENST00000358655.8
tryptophanyl-tRNA synthetase 1
chr12_-_109833373 0.32 ENST00000261740.7
transient receptor potential cation channel subfamily V member 4
chr1_-_112935984 0.32 ENST00000443580.6
solute carrier family 16 member 1
chr1_-_150808251 0.32 ENST00000271651.8
ENST00000676970.1
ENST00000679260.1
ENST00000676751.1
ENST00000677887.1
cathepsin K
chr10_-_96271508 0.32 ENST00000427367.6
ENST00000413476.6
ENST00000371176.6
B cell linker
chr15_+_92900338 0.31 ENST00000625990.3
chromodomain helicase DNA binding protein 2
chr12_+_93677556 0.31 ENST00000542893.2
CASP2 and RIPK1 domain containing adaptor with death domain
chr17_+_4948252 0.31 ENST00000520221.5
enolase 3
chr15_+_67138001 0.31 ENST00000439724.7
SMAD family member 3
chr2_+_108377947 0.31 ENST00000272452.7
sulfotransferase family 1C member 4
chr16_+_30896606 0.31 ENST00000279804.3
ENST00000395019.3
cardiotrophin 1
chr5_+_96743536 0.31 ENST00000515663.5
calpastatin
chr6_-_155314444 0.31 ENST00000367166.5
transcription factor B1, mitochondrial
chr21_+_42403856 0.30 ENST00000291535.11
ubiquitin associated and SH3 domain containing A
chr2_+_118088432 0.30 ENST00000245787.9
insulin induced gene 2
chr7_+_44044634 0.30 ENST00000490734.6
drebrin like
chr19_-_48249771 0.30 ENST00000522431.5
ENST00000520153.5
ENST00000520015.5
caspase recruitment domain family member 8
chr14_-_106374129 0.30 ENST00000390616.2
immunoglobulin heavy variable 4-34
chr22_-_37244417 0.30 ENST00000405484.5
ENST00000441619.5
ENST00000406508.5
Rac family small GTPase 2
chr14_+_64715677 0.30 ENST00000634379.2
pleckstrin homology and RhoGEF domain containing G3
chr2_+_233251571 0.30 ENST00000347464.9
ENST00000444735.5
ENST00000373525.9
ENST00000392017.9
ENST00000419681.5
autophagy related 16 like 1
chr8_+_38728550 0.30 ENST00000520340.5
ENST00000518415.5
transforming acidic coiled-coil containing protein 1
chr17_+_35587478 0.29 ENST00000618940.4
adaptor related protein complex 2 subunit beta 1
chr10_+_73744346 0.29 ENST00000345254.9
ENST00000339365.2
SEC24 homolog C, COPII coat complex component
chr1_+_27879638 0.29 ENST00000456990.1
thymocyte selection associated family member 2
chr5_-_128537821 0.29 ENST00000508989.5
fibrillin 2
chr17_+_2796404 0.29 ENST00000366401.8
ENST00000254695.13
ENST00000542807.1
RAP1 GTPase activating protein 2
chr1_+_32222415 0.29 ENST00000678420.1
ENST00000678162.1
ENST00000678711.1
ENST00000678883.1
ENST00000677353.1
ENST00000355082.10
eukaryotic translation initiation factor 3 subunit I
chr3_-_179451387 0.29 ENST00000675901.1
ENST00000232564.8
ENST00000674862.1
ENST00000497513.1
G protein subunit beta 4
chr9_-_83956677 0.28 ENST00000376344.8
chromosome 9 open reading frame 64
chr1_+_209768482 0.28 ENST00000367023.5
TRAF3 interacting protein 3
chr3_+_4493442 0.28 ENST00000456211.8
ENST00000443694.5
ENST00000648266.1
inositol 1,4,5-trisphosphate receptor type 1
chr2_+_233251694 0.28 ENST00000417017.5
ENST00000392020.8
ENST00000392018.1
autophagy related 16 like 1
chr16_-_18876305 0.28 ENST00000563235.5
SMG1 nonsense mediated mRNA decay associated PI3K related kinase
chr19_-_52171443 0.28 ENST00000598982.5
ENST00000594362.1
ENST00000597252.5
novel transcript
zinc finger protein 836
chr6_-_109455698 0.28 ENST00000431946.1
ENST00000358577.7
ENST00000358807.8
microtubule associated monooxygenase, calponin and LIM domain containing 1
chr1_+_32222393 0.28 ENST00000676679.1
ENST00000678689.1
ENST00000373586.2
ENST00000679290.1
ENST00000677378.1
ENST00000678534.1
ENST00000678968.1
ENST00000678063.1
ENST00000678150.1
ENST00000677198.1
ENST00000677540.1
eukaryotic translation initiation factor 3 subunit I
chr4_-_48080172 0.28 ENST00000507351.1
TXK tyrosine kinase
chr12_-_9999176 0.28 ENST00000298527.10
ENST00000348658.4
C-type lectin domain family 1 member B
chr3_-_183555696 0.27 ENST00000341319.8
kelch like family member 6
chr12_-_21941300 0.27 ENST00000684084.1
ATP binding cassette subfamily C member 9
chr7_+_99598255 0.27 ENST00000431679.6
ENST00000453227.5
transmembrane protein 225B
chrX_-_154371210 0.27 ENST00000369856.8
ENST00000422373.6
ENST00000360319.9
filamin A
chr9_-_112333562 0.27 ENST00000343327.6
polypyrimidine tract binding protein 3
chr7_+_150323239 0.27 ENST00000323078.7
ENST00000493307.1
ENST00000359623.9
leucine rich repeat containing 61
chr2_-_36966471 0.27 ENST00000379213.3
striatin
chr17_+_2056073 0.27 ENST00000576444.1
ENST00000322941.3
HIC ZBTB transcriptional repressor 1
chr7_+_44044663 0.27 ENST00000456905.5
ENST00000440166.5
ENST00000452943.5
ENST00000448521.6
ENST00000468694.5
ENST00000494774.5
drebrin like
chrX_-_120560884 0.26 ENST00000404115.8
cullin 4B
chr3_+_28348695 0.26 ENST00000383768.7
zinc finger CW-type and PWWP domain containing 2
chr11_+_63839086 0.26 ENST00000350490.11
ENST00000402010.8
microtubule affinity regulating kinase 2
chrX_+_15507302 0.26 ENST00000342014.6
BMX non-receptor tyrosine kinase
chr3_+_4493471 0.26 ENST00000544951.6
ENST00000650294.1
inositol 1,4,5-trisphosphate receptor type 1
chr17_+_80415447 0.26 ENST00000520136.6
ENST00000520284.5
ENST00000517795.5
ENST00000523228.5
ENST00000523828.5
ENST00000522200.5
ENST00000521565.5
ENST00000518907.5
ENST00000518644.5
ENST00000518901.5
endonuclease V
chr2_+_113059194 0.26 ENST00000393200.7
interleukin 36 receptor antagonist
chr6_-_168075831 0.26 ENST00000440994.6
FERM domain containing 1
chr3_+_190615308 0.26 ENST00000412080.1
interleukin 1 receptor accessory protein
chr17_+_42458844 0.25 ENST00000393829.6
ENST00000537728.5
ENST00000343619.9
ENST00000264649.10
ENST00000585525.5
ENST00000544137.5
ENST00000589727.5
ENST00000587824.5
ATPase H+ transporting V0 subunit a1
chr19_-_45424364 0.25 ENST00000589165.5
ERCC excision repair 1, endonuclease non-catalytic subunit
chr4_-_176792913 0.25 ENST00000618562.2
vascular endothelial growth factor C
chr11_+_119168705 0.25 ENST00000409109.6
ENST00000409991.5
ENST00000292199.6
NLR family member X1
chrX_+_23908006 0.25 ENST00000379211.8
ENST00000648352.1
chromosome X open reading frame 58
chr11_-_82997477 0.25 ENST00000534301.5
RAB30, member RAS oncogene family
chr1_-_85276467 0.25 ENST00000648566.1
BCL10 immune signaling adaptor
chr20_+_3786772 0.25 ENST00000344256.10
ENST00000379598.9
cell division cycle 25B
chr4_-_151325488 0.25 ENST00000604030.7
SH3 domain containing 19
chr3_+_46987972 0.24 ENST00000651747.1
neurobeachin like 2
chr11_+_63839005 0.24 ENST00000508192.5
ENST00000361128.9
microtubule affinity regulating kinase 2
chr8_+_27311471 0.24 ENST00000397501.5
protein tyrosine kinase 2 beta
chr4_-_151227881 0.24 ENST00000652233.1
ENST00000514152.5
SH3 domain containing 19
chr9_+_34652167 0.24 ENST00000441545.7
ENST00000553620.5
interleukin 11 receptor subunit alpha
chr11_-_28108109 0.24 ENST00000263181.7
kinesin family member 18A
chr6_+_34236865 0.24 ENST00000674029.1
ENST00000447654.5
ENST00000347617.10
ENST00000401473.7
ENST00000311487.9
high mobility group AT-hook 1
chr1_+_28328994 0.24 ENST00000373842.9
ENST00000398997.2
mediator complex subunit 18
chr10_-_70602687 0.23 ENST00000638674.1
perforin 1
chr19_+_10928777 0.23 ENST00000270502.7
translocase of inner mitochondrial membrane 29
chr2_+_167135901 0.23 ENST00000628543.2
xin actin binding repeat containing 2
chr8_-_37899454 0.23 ENST00000522727.5
ENST00000287263.8
ENST00000330843.9
RAB11 family interacting protein 1
chr17_-_45410414 0.23 ENST00000532038.5
ENST00000528677.1
Rho GTPase activating protein 27
chr13_-_60163869 0.23 ENST00000400324.9
diaphanous related formin 3
chr22_-_35840218 0.23 ENST00000414461.6
ENST00000416721.6
ENST00000449924.6
ENST00000262829.11
ENST00000397305.3
RNA binding fox-1 homolog 2
chr20_+_9514562 0.23 ENST00000246070.3
lysosomal associated membrane protein family member 5
chr3_+_9902619 0.23 ENST00000421412.5
interleukin 17 receptor E
chr6_-_130970428 0.23 ENST00000529208.5
erythrocyte membrane protein band 4.1 like 2
chr4_+_76251694 0.23 ENST00000510328.5
ENST00000424749.7
ENST00000502320.2
ENST00000515604.5
family with sequence similarity 47 member E
FAM47E-STBD1 readthrough
chr12_-_610407 0.22 ENST00000397265.7
ninjurin 2
chr7_+_157336988 0.22 ENST00000262177.9
ENST00000417758.5
ENST00000443280.5
DnaJ heat shock protein family (Hsp40) member B6
chr6_-_32816910 0.22 ENST00000447394.1
ENST00000438763.7
major histocompatibility complex, class II, DO beta
chr16_+_66604100 0.22 ENST00000562357.5
ENST00000562707.5
ENST00000361909.8
ENST00000460097.5
ENST00000565666.5
CKLF like MARVEL transmembrane domain containing 3
chr13_+_31846713 0.22 ENST00000645780.1
FRY microtubule binding protein
chr2_-_151261839 0.22 ENST00000331426.6
RNA binding motif protein 43
chr6_-_42142604 0.22 ENST00000356542.5
ENST00000341865.9
chromosome 6 open reading frame 132
chr17_+_4950147 0.22 ENST00000522301.5
enolase 3
chr14_+_67720842 0.22 ENST00000267502.3
retinol dehydrogenase 12
chr4_-_10021490 0.22 ENST00000264784.8
solute carrier family 2 member 9
chr11_+_65639860 0.22 ENST00000527525.5
signal-induced proliferation-associated 1
chr11_+_63838902 0.22 ENST00000377810.8
microtubule affinity regulating kinase 2
chr13_+_45464995 0.22 ENST00000617493.1
component of oligomeric golgi complex 3
chr1_-_63523175 0.22 ENST00000371092.7
ENST00000271002.15
integrin subunit beta 3 binding protein
chr19_-_52171600 0.21 ENST00000682614.1
zinc finger protein 836
chr5_-_139482285 0.21 ENST00000652110.1
stimulator of interferon response cGAMP interactor 1
chr9_+_2621766 0.21 ENST00000382100.8
very low density lipoprotein receptor
chr9_+_2621556 0.21 ENST00000680746.1
very low density lipoprotein receptor
chr1_+_89364051 0.21 ENST00000370456.5
guanylate binding protein family member 6
chr12_+_112418889 0.21 ENST00000392597.5
protein tyrosine phosphatase non-receptor type 11

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0002665 negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017)
0.3 1.3 GO:0044565 dendritic cell proliferation(GO:0044565)
0.2 0.7 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.2 0.9 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1 0.4 GO:0098758 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.1 0.7 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 0.8 GO:0021553 olfactory nerve development(GO:0021553)
0.1 0.3 GO:0032641 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.1 0.2 GO:2000537 regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.1 0.5 GO:0002540 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.1 0.6 GO:0002357 defense response to tumor cell(GO:0002357)
0.1 0.3 GO:0007231 osmosensory signaling pathway(GO:0007231)
0.1 0.4 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.1 0.8 GO:0046061 dGTP catabolic process(GO:0006203) dATP catabolic process(GO:0046061)
0.1 0.4 GO:0035744 T-helper 1 cell cytokine production(GO:0035744)
0.1 0.7 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.1 0.6 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.1 0.5 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.5 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.9 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 0.5 GO:0030035 microspike assembly(GO:0030035)
0.1 0.3 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.1 0.4 GO:0099543 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
0.1 0.6 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.1 0.3 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.1 0.6 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.1 0.2 GO:1902365 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.1 0.3 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
0.1 0.3 GO:0001927 exocyst assembly(GO:0001927)
0.1 0.4 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.1 0.2 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.1 0.2 GO:1901254 modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
0.1 1.2 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 0.2 GO:1905237 response to cyclosporin A(GO:1905237) positive regulation of response to drug(GO:2001025)
0.1 0.2 GO:0031938 regulation of chromatin silencing at telomere(GO:0031938)
0.1 0.2 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.1 0.3 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.1 1.0 GO:0070914 UV-damage excision repair(GO:0070914)
0.1 0.7 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.4 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 0.2 GO:0032826 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.1 0.4 GO:0097338 response to clozapine(GO:0097338)
0.1 0.4 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.1 0.2 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.1 0.3 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.1 0.2 GO:0036451 cap mRNA methylation(GO:0036451)
0.1 0.1 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.1 0.2 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.1 0.2 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.1 0.2 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.2 GO:0042631 cellular response to water deprivation(GO:0042631)
0.1 0.4 GO:0034436 glycoprotein transport(GO:0034436)
0.1 0.4 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.2 GO:0035048 splicing factor protein import into nucleus(GO:0035048)
0.1 0.1 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.1 0.3 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.2 GO:0021503 neural fold bending(GO:0021503)
0.1 0.6 GO:0001865 NK T cell differentiation(GO:0001865)
0.1 0.4 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0 0.5 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.2 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.0 0.7 GO:0007144 female meiosis I(GO:0007144)
0.0 0.2 GO:0052251 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.0 0.4 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.1 GO:0016487 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488)
0.0 0.3 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.5 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.3 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.4 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.2 GO:0045626 negative regulation of T-helper 1 cell differentiation(GO:0045626)
0.0 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.2 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.4 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 1.6 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.0 0.6 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
0.0 0.1 GO:0002585 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.0 0.2 GO:0046203 spermidine catabolic process(GO:0046203)
0.0 0.2 GO:0090299 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.0 0.1 GO:1902309 regulation of heart rate by hormone(GO:0003064) negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.2 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.0 0.1 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.0 0.2 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.0 0.3 GO:0007506 gonadal mesoderm development(GO:0007506)
0.0 0.2 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.0 0.3 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 0.3 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.0 0.1 GO:0038091 VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
0.0 0.1 GO:0060003 copper ion export(GO:0060003) cellular response to lead ion(GO:0071284)
0.0 0.2 GO:0098728 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.2 GO:0009624 response to nematode(GO:0009624)
0.0 0.2 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.5 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.1 GO:0051463 negative regulation of cortisol secretion(GO:0051463)
0.0 0.3 GO:0036018 cellular response to erythropoietin(GO:0036018)
0.0 0.1 GO:0060528 regulation of translational initiation by iron(GO:0006447) secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.3 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.0 0.3 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.4 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.4 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.4 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.2 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.1 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.0 0.3 GO:0015886 heme transport(GO:0015886)
0.0 0.4 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.4 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.2 GO:0043606 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.3 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 0.1 GO:0090135 actin filament branching(GO:0090135)
0.0 0.2 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0 0.3 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.0 0.1 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.0 0.4 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0 0.2 GO:0019740 regulation of nitrogen utilization(GO:0006808) nitrogen utilization(GO:0019740)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.8 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.1 GO:0035552 oxidative single-stranded DNA demethylation(GO:0035552)
0.0 0.2 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.0 0.1 GO:1903259 exon-exon junction complex disassembly(GO:1903259)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.1 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.2 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.1 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.1 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.0 0.6 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.4 GO:0046541 saliva secretion(GO:0046541)
0.0 0.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.5 GO:0045076 regulation of interleukin-2 biosynthetic process(GO:0045076)
0.0 0.1 GO:0044007 negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010768) transmission of virus(GO:0019089) dissemination or transmission of symbiont from host(GO:0044007) dissemination or transmission of organism from other organism involved in symbiotic interaction(GO:0051821)
0.0 0.0 GO:0090241 negative regulation of histone H4 acetylation(GO:0090241)
0.0 0.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of fibrinolysis(GO:0051919)
0.0 0.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.1 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.1 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.6 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.1 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.1 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.5 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.6 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.1 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.5 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.1 GO:0036269 swimming behavior(GO:0036269)
0.0 0.2 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.0 0.1 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
0.0 0.1 GO:1900081 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of adrenergic receptor signaling pathway(GO:0071878) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204) negative regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901205) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.0 0.1 GO:1904073 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.0 0.3 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.3 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.4 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.4 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.3 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.1 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.0 0.3 GO:0002467 germinal center formation(GO:0002467)
0.0 0.1 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.1 GO:0019075 virus maturation(GO:0019075)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.1 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.2 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.0 0.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.0 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.0 GO:0032470 positive regulation of endoplasmic reticulum calcium ion concentration(GO:0032470)
0.0 0.2 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.3 GO:0060363 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cranial suture morphogenesis(GO:0060363) cellular response to sterol depletion(GO:0071501)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.1 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.5 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.1 GO:0001555 oocyte growth(GO:0001555) regulation of progesterone secretion(GO:2000870)
0.0 0.1 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.0 0.6 GO:0042554 superoxide anion generation(GO:0042554)
0.0 0.2 GO:0060215 primitive hemopoiesis(GO:0060215)
0.0 0.0 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.0 0.1 GO:0071504 cellular response to heparin(GO:0071504)
0.0 0.1 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0 0.1 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.1 GO:0046968 peptide antigen transport(GO:0046968)
0.0 0.1 GO:0016121 tetraterpenoid metabolic process(GO:0016108) carotenoid metabolic process(GO:0016116) carotene catabolic process(GO:0016121) xanthophyll metabolic process(GO:0016122) terpene catabolic process(GO:0046247)
0.0 0.1 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.0 GO:2000553 positive regulation of T-helper 2 cell cytokine production(GO:2000553)
0.0 0.2 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.3 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.0 0.2 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.3 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 1.0 GO:0061621 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.2 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.2 GO:0070836 caveola assembly(GO:0070836)
0.0 0.1 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.0 0.1 GO:2000510 positive regulation of dendritic cell chemotaxis(GO:2000510)
0.0 0.1 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.0 0.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.1 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.1 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.2 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.1 GO:0060721 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.0 0.4 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 1.2 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.2 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.0 GO:0036245 cellular response to menadione(GO:0036245)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.0 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.0 0.2 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.1 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.1 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.0 0.1 GO:1905247 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.0 0.0 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.0 GO:1903233 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.2 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.0 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.2 GO:0021817 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.2 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.9 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:0007135 meiosis II(GO:0007135)
0.0 0.7 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.1 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.1 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.0 GO:0044725 chromatin reprogramming in the zygote(GO:0044725)
0.0 0.1 GO:1904306 regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306)
0.0 0.1 GO:0071422 succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422)
0.0 0.0 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.0 0.2 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.2 GO:0060717 chorio-allantoic fusion(GO:0060710) chorion development(GO:0060717)
0.0 0.3 GO:0031529 ruffle organization(GO:0031529)
0.0 0.1 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.1 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.0 0.2 GO:0033622 integrin activation(GO:0033622)
0.0 0.5 GO:0030220 platelet formation(GO:0030220)
0.0 0.0 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.0 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.1 GO:0045963 cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963) positive regulation of homocysteine metabolic process(GO:0050668)
0.0 0.2 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.0 0.2 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.0 GO:0010749 regulation of nitric oxide mediated signal transduction(GO:0010749)
0.0 0.3 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0 0.1 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.7 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.1 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.2 GO:0090344 negative regulation of cell aging(GO:0090344)
0.0 2.1 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.1 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.2 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 0.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.1 GO:1902969 mitotic DNA replication(GO:1902969)
0.0 0.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.0 GO:0050904 diapedesis(GO:0050904)
0.0 0.5 GO:0001783 B cell apoptotic process(GO:0001783)
0.0 0.2 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 0.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.1 GO:0046102 adenosine catabolic process(GO:0006154) inosine metabolic process(GO:0046102) inosine biosynthetic process(GO:0046103)
0.0 0.1 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.1 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.1 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.1 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.2 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.1 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.9 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.1 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.3 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.3 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.1 GO:0098706 ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.4 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.1 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 0.2 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.1 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.2 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.3 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.0 GO:0038178 complement component C5a signaling pathway(GO:0038178)
0.0 0.1 GO:0051414 response to cortisol(GO:0051414)
0.0 0.1 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.0 0.2 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.0 GO:1904849 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.0 0.0 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.9 GO:0090307 mitotic spindle assembly(GO:0090307)
0.0 0.2 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.0 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.0 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.0 0.5 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0032532 regulation of microvillus length(GO:0032532)
0.0 0.1 GO:2000819 regulation of nucleotide-excision repair(GO:2000819)
0.0 0.1 GO:0002051 osteoblast fate commitment(GO:0002051)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0032449 CBM complex(GO:0032449)
0.1 1.2 GO:0097427 microtubule bundle(GO:0097427)
0.1 0.5 GO:1990425 ryanodine receptor complex(GO:1990425)
0.1 0.9 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 1.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 1.4 GO:0008091 spectrin(GO:0008091)
0.1 0.2 GO:1902737 dendritic filopodium(GO:1902737)
0.1 0.6 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.1 0.2 GO:0060342 photoreceptor inner segment membrane(GO:0060342)
0.1 0.7 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.2 GO:0036117 hyaluranon cable(GO:0036117)
0.1 0.2 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.1 0.7 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.6 GO:0044194 cytolytic granule(GO:0044194)
0.1 0.6 GO:0032010 phagolysosome(GO:0032010)
0.1 0.4 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.1 0.2 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.1 0.2 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.2 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.1 0.5 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.4 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.4 GO:0070847 core mediator complex(GO:0070847)
0.1 0.3 GO:0031523 Myb complex(GO:0031523)
0.1 0.2 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.1 0.2 GO:1990075 periciliary membrane compartment(GO:1990075)
0.0 0.4 GO:0043203 axon hillock(GO:0043203)
0.0 0.5 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.1 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.0 0.7 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.7 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.4 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.1 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
0.0 0.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.2 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.1 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.2 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 0.2 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.3 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.3 GO:0043196 varicosity(GO:0043196)
0.0 0.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.8 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 2.4 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.2 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.9 GO:0030128 clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.2 GO:0000796 condensin complex(GO:0000796)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.1 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.6 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.0 0.0 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 0.1 GO:0005760 gamma DNA polymerase complex(GO:0005760)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.3 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.5 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.5 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.2 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 1.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0020003 symbiont-containing vacuole(GO:0020003)
0.0 0.2 GO:0031298 replication fork protection complex(GO:0031298)
0.0 1.0 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.1 GO:0051286 cell tip(GO:0051286)
0.0 0.5 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.0 GO:0030689 Noc complex(GO:0030689)
0.0 0.2 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.0 0.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.1 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.1 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.1 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.1 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.2 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.4 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0035363 histone locus body(GO:0035363)
0.0 0.2 GO:0044613 nuclear pore central transport channel(GO:0044613)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0044713 GTP diphosphatase activity(GO:0036219) 2-hydroxy-adenosine triphosphate pyrophosphatase activity(GO:0044713) 2-hydroxy-(deoxy)adenosine-triphosphate pyrophosphatase activity(GO:0044714) ATP diphosphatase activity(GO:0047693)
0.1 0.4 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.9 GO:0005166 neurotrophin p75 receptor binding(GO:0005166) nerve growth factor receptor activity(GO:0010465)
0.1 0.7 GO:0032810 sterol response element binding(GO:0032810)
0.1 1.4 GO:0042731 PH domain binding(GO:0042731)
0.1 0.7 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 0.5 GO:0032089 NACHT domain binding(GO:0032089)
0.1 0.8 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.4 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 0.4 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.1 0.3 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.1 0.4 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 0.4 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.9 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.4 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 0.3 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 0.7 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.1 0.6 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.1 0.4 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 0.6 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.3 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 0.3 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 0.4 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.2 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.1 0.3 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 1.0 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.2 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.1 0.3 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.3 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.1 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.2 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.1 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0055100 adiponectin binding(GO:0055100)
0.0 0.5 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 1.0 GO:0070513 death domain binding(GO:0070513)
0.0 0.2 GO:0005471 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.0 0.3 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 0.1 GO:0045550 geranylgeranyl reductase activity(GO:0045550)
0.0 0.6 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.4 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.2 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.2 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.0 0.4 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.6 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.4 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.2 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0 0.2 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.1 GO:0004618 copper-exporting ATPase activity(GO:0004008) phosphoglycerate kinase activity(GO:0004618) copper-transporting ATPase activity(GO:0043682)
0.0 0.5 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.3 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.3 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.0 0.5 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.3 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.3 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 1.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.6 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.1 GO:0052815 medium-chain acyl-CoA hydrolase activity(GO:0052815) long-chain acyl-CoA hydrolase activity(GO:0052816)
0.0 0.1 GO:0098808 mRNA cap binding(GO:0098808)
0.0 0.7 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.1 GO:0035514 DNA demethylase activity(GO:0035514)
0.0 0.2 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.2 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.6 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.2 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.4 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.0 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0 0.2 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.3 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.1 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.0 0.4 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.2 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.2 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.1 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.0 1.2 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.1 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.0 0.5 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.3 GO:0004673 protein histidine kinase activity(GO:0004673)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.2 GO:0089720 caspase binding(GO:0089720)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.2 GO:0043426 MRF binding(GO:0043426)
0.0 0.3 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.9 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.2 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.1 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.1 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.3 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.2 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.1 GO:0008859 exoribonuclease II activity(GO:0008859)
0.0 0.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.3 GO:0031702 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.0 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.0 0.0 GO:0098918 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.0 0.2 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0016297 oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297)
0.0 0.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.3 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.0 0.1 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 1.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0015141 succinate transmembrane transporter activity(GO:0015141)
0.0 0.7 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.6 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0 0.6 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.5 GO:0022829 wide pore channel activity(GO:0022829)
0.0 0.2 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0039706 co-receptor binding(GO:0039706)
0.0 1.0 GO:0019843 rRNA binding(GO:0019843)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0070004 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.0 0.1 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.0 0.6 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.2 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.0 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.0 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.0 0.1 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.1 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.3 GO:0017166 vinculin binding(GO:0017166)
0.0 0.4 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.0 0.1 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.1 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.1 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.0 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.0 0.3 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.0 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 0.1 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.0 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.2 GO:0005095 GTPase inhibitor activity(GO:0005095)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.9 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 1.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 3.8 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 1.6 PID AURORA A PATHWAY Aurora A signaling
0.0 0.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.4 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.3 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 2.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.3 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.6 ST GAQ PATHWAY G alpha q Pathway
0.0 0.9 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.4 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.1 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.3 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.4 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.4 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.6 PID AURORA B PATHWAY Aurora B signaling
0.0 0.6 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.7 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.0 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.1 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.4 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 1.3 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 1.4 REACTOME KINESINS Genes involved in Kinesins
0.0 0.5 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.2 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 2.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.1 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.9 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.8 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.5 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.4 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.4 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.6 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.5 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.1 REACTOME SIGNALLING TO RAS Genes involved in Signalling to RAS
0.0 0.7 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.5 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 1.2 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.3 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.1 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.2 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.1 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.2 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.6 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.4 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 1.0 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling