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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for FOSB

Z-value: 0.55

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Transcription factors associated with FOSB

Gene Symbol Gene ID Gene Info
FOSB
ENSG00000125740.14 FOSB

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOSBhg38_v1_chr19_+_45469841_454699130.393.5e-02Click!

Activity profile of FOSB motif

Sorted Z-values of FOSB motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FOSB

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr1_+_152908538 2.00 ENST00000368764.4
IVL
involucrin
chr18_+_23873000 1.87 ENST00000269217.11
ENST00000587184.5
LAMA3
laminin subunit alpha 3
chr1_-_153057504 1.78 ENST00000392653.3
SPRR2A
small proline rich protein 2A
chr19_-_35528221 1.43 ENST00000588674.5
ENST00000452271.7
ENST00000518157.1
SBSN
suprabasin
chr1_-_153094521 1.26 ENST00000368750.8
SPRR2E
small proline rich protein 2E
chr17_-_41612757 1.21 ENST00000301653.9
ENST00000593067.1
KRT16
keratin 16
chr11_-_65900375 1.18 ENST00000312562.7
FOSL1
FOS like 1, AP-1 transcription factor subunit
chr6_+_73695779 1.18 ENST00000422508.6
ENST00000437994.6
CD109
CD109 molecule
chr6_+_73696145 1.14 ENST00000287097.6
CD109
CD109 molecule
chr1_-_153113507 1.13 ENST00000468739.2
SPRR2F
small proline rich protein 2F
chr1_-_153549238 1.08 ENST00000368713.8
S100A3
S100 calcium binding protein A3
chr12_+_53098846 1.04 ENST00000650247.1
ENST00000549628.1
IGFBP6
insulin like growth factor binding protein 6
chr11_-_65900413 0.99 ENST00000448083.6
ENST00000531493.5
ENST00000532401.1
FOSL1
FOS like 1, AP-1 transcription factor subunit
chr1_-_153041111 0.97 ENST00000360379.4
SPRR2D
small proline rich protein 2D
chr3_-_48595267 0.97 ENST00000328333.12
ENST00000681320.1
COL7A1
collagen type VII alpha 1 chain
chr1_-_153549120 0.97 ENST00000368712.1
S100A3
S100 calcium binding protein A3
chr22_+_31082860 0.90 ENST00000619644.4
SMTN
smoothelin
chr12_-_95116967 0.90 ENST00000551521.5
FGD6
FYVE, RhoGEF and PH domain containing 6
chr19_-_51065067 0.84 ENST00000595547.5
ENST00000335422.3
ENST00000595793.6
ENST00000596955.1
KLK13
kallikrein related peptidase 13
chr3_+_172754457 0.83 ENST00000441497.6
ECT2
epithelial cell transforming 2
chr5_+_136059151 0.81 ENST00000503087.1
TGFBI
transforming growth factor beta induced
chr10_+_17228215 0.80 ENST00000544301.7
VIM
vimentin
chr11_-_102798148 0.75 ENST00000315274.7
MMP1
matrix metallopeptidase 1
chr19_-_35513641 0.73 ENST00000339686.8
ENST00000447113.6
DMKN
dermokine
chr18_+_63775369 0.69 ENST00000540675.5
SERPINB7
serpin family B member 7
chr19_-_48511793 0.62 ENST00000600059.6
LMTK3
lemur tyrosine kinase 3
chr15_+_67166019 0.62 ENST00000537194.6
SMAD3
SMAD family member 3
chr5_-_177496845 0.61 ENST00000506537.1
PDLIM7
PDZ and LIM domain 7
chr6_+_47698538 0.60 ENST00000327753.7
ADGRF4
adhesion G protein-coupled receptor F4
chr6_+_47698574 0.60 ENST00000283303.3
ADGRF4
adhesion G protein-coupled receptor F4
chr17_+_76385256 0.59 ENST00000392496.3
SPHK1
sphingosine kinase 1
chr18_+_63775395 0.59 ENST00000398019.7
SERPINB7
serpin family B member 7
chr15_+_67125707 0.58 ENST00000540846.6
SMAD3
SMAD family member 3
chr19_+_46601237 0.57 ENST00000597743.5
CALM3
calmodulin 3
chr19_-_35501878 0.56 ENST00000593342.5
ENST00000601650.1
ENST00000408915.6
DMKN
dermokine
chr5_-_177496802 0.54 ENST00000506161.5
PDLIM7
PDZ and LIM domain 7
chr2_-_65366650 0.53 ENST00000443619.6
SPRED2
sprouty related EVH1 domain containing 2
chr16_-_30113528 0.52 ENST00000406256.8
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr1_+_26280117 0.49 ENST00000319041.6
SH3BGRL3
SH3 domain binding glutamate rich protein like 3
chr11_+_706595 0.47 ENST00000531348.5
ENST00000530636.5
EPS8L2
EPS8 like 2
chr1_+_89364051 0.45 ENST00000370456.5
GBP6
guanylate binding protein family member 6
chr1_+_22007450 0.45 ENST00000400271.2
CELA3A
chymotrypsin like elastase 3A
chr18_+_63476927 0.45 ENST00000489441.5
ENST00000382771.9
ENST00000424602.1
SERPINB5
serpin family B member 5
chr4_+_83536097 0.44 ENST00000395226.6
ENST00000264409.5
GPAT3
glycerol-3-phosphate acyltransferase 3
chr19_-_38773432 0.44 ENST00000599035.1
ENST00000378626.5
LGALS7
galectin 7
chr19_-_35490456 0.43 ENST00000338897.4
ENST00000484218.6
KRTDAP
keratinocyte differentiation associated protein
chr7_+_143381286 0.43 ENST00000449630.5
ENST00000322764.10
ENST00000457235.5
ZYX
zyxin
chr6_+_32153441 0.42 ENST00000414204.5
ENST00000361568.6
ENST00000395523.5
PPT2
palmitoyl-protein thioesterase 2
chr12_-_54419259 0.42 ENST00000293379.9
ITGA5
integrin subunit alpha 5
chr7_+_134843884 0.41 ENST00000445569.6
CALD1
caldesmon 1
chr11_-_64759967 0.41 ENST00000377432.7
ENST00000164139.4
PYGM
glycogen phosphorylase, muscle associated
chr17_-_19004727 0.40 ENST00000388995.11
FAM83G
family with sequence similarity 83 member G
chr14_+_94026314 0.40 ENST00000203664.10
ENST00000553723.1
OTUB2
OTU deubiquitinase, ubiquitin aldehyde binding 2
chr19_+_46601296 0.38 ENST00000598871.5
ENST00000291295.14
ENST00000594523.5
CALM3
calmodulin 3
chr17_+_75721451 0.37 ENST00000200181.8
ITGB4
integrin subunit beta 4
chr8_+_86098901 0.36 ENST00000285393.4
ATP6V0D2
ATPase H+ transporting V0 subunit d2
chr20_-_653189 0.34 ENST00000381962.4
SRXN1
sulfiredoxin 1
chr2_-_118847638 0.32 ENST00000295206.7
EN1
engrailed homeobox 1
chr9_+_4985227 0.32 ENST00000381652.4
JAK2
Janus kinase 2
chr6_-_43629222 0.32 ENST00000307126.10
GTPBP2
GTP binding protein 2
chr17_-_41055211 0.31 ENST00000542910.1
ENST00000398477.1
KRTAP2-2
keratin associated protein 2-2
chr8_-_124372686 0.31 ENST00000297632.8
TMEM65
transmembrane protein 65
chr9_-_107489754 0.31 ENST00000610832.1
ENST00000374672.5
KLF4
Kruppel like factor 4
chr12_-_8612850 0.30 ENST00000229335.11
ENST00000537228.5
AICDA
activation induced cytidine deaminase
chr17_+_4950147 0.29 ENST00000522301.5
ENO3
enolase 3
chr11_+_706196 0.29 ENST00000534755.5
ENST00000650127.1
EPS8L2
EPS8 like 2
chr1_+_203026481 0.29 ENST00000367240.6
PPFIA4
PTPRF interacting protein alpha 4
chr10_-_29634964 0.29 ENST00000375398.6
ENST00000355867.8
SVIL
supervillin
chr5_-_16916400 0.29 ENST00000513882.5
MYO10
myosin X
chr12_-_94616061 0.28 ENST00000551457.1
TMCC3
transmembrane and coiled-coil domain family 3
chr11_-_2903490 0.28 ENST00000455942.3
ENST00000625099.4
SLC22A18AS
solute carrier family 22 member 18 antisense
chr1_+_156126160 0.27 ENST00000448611.6
ENST00000368297.5
LMNA
lamin A/C
chr5_+_14664653 0.27 ENST00000284274.5
OTULIN
OTU deubiquitinase with linear linkage specificity
chr3_-_125055987 0.26 ENST00000311127.9
HEG1
heart development protein with EGF like domains 1
chr19_-_43670153 0.26 ENST00000601723.5
ENST00000339082.7
ENST00000340093.8
PLAUR
plasminogen activator, urokinase receptor
chr10_+_84328625 0.26 ENST00000224756.12
CCSER2
coiled-coil serine rich protein 2
chr11_+_706222 0.26 ENST00000318562.13
ENST00000533500.5
EPS8L2
EPS8 like 2
chr8_-_142614469 0.25 ENST00000356613.4
ARC
activity regulated cytoskeleton associated protein
chr2_-_203535253 0.25 ENST00000457812.5
ENST00000319170.10
ENST00000630330.2
ENST00000308091.8
ENST00000453034.5
ENST00000420371.2
RAPH1
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr6_-_35921047 0.25 ENST00000361690.7
ENST00000512445.5
SRPK1
SRSF protein kinase 1
chr11_+_706117 0.25 ENST00000533256.5
ENST00000614442.4
EPS8L2
EPS8 like 2
chr4_-_88158605 0.25 ENST00000237612.8
ABCG2
ATP binding cassette subfamily G member 2 (Junior blood group)
chr11_-_102955705 0.24 ENST00000615555.4
ENST00000340273.4
ENST00000260302.8
MMP13
matrix metallopeptidase 13
chr17_-_8118489 0.24 ENST00000380149.6
ENST00000448843.7
ALOXE3
arachidonate lipoxygenase 3
chr4_-_79408198 0.24 ENST00000358842.5
GK2
glycerol kinase 2
chr17_-_41786688 0.24 ENST00000310706.9
ENST00000393931.8
ENST00000424457.5
ENST00000591690.5
JUP
junction plakoglobin
chr7_+_2647703 0.23 ENST00000403167.5
TTYH3
tweety family member 3
chr18_+_44700796 0.23 ENST00000677130.1
SETBP1
SET binding protein 1
chr19_+_926001 0.22 ENST00000263620.8
ARID3A
AT-rich interaction domain 3A
chr6_-_35921079 0.22 ENST00000507909.1
ENST00000373825.7
SRPK1
SRSF protein kinase 1
chr6_-_35921128 0.22 ENST00000510290.5
ENST00000423325.6
SRPK1
SRSF protein kinase 1
chrX_+_49171889 0.21 ENST00000376327.6
PLP2
proteolipid protein 2
chr2_-_135876382 0.21 ENST00000264156.3
MCM6
minichromosome maintenance complex component 6
chr11_-_66336396 0.21 ENST00000627248.1
ENST00000311320.9
RIN1
Ras and Rab interactor 1
chr8_-_142742398 0.20 ENST00000246515.2
SLURP1
secreted LY6/PLAUR domain containing 1
chr17_-_35063648 0.20 ENST00000394597.7
RFFL
ring finger and FYVE like domain containing E3 ubiquitin protein ligase
chr11_-_11353241 0.20 ENST00000528848.3
CSNK2A3
casein kinase 2 alpha 3
chr8_-_67746348 0.20 ENST00000297770.10
CPA6
carboxypeptidase A6
chr2_+_190343561 0.20 ENST00000322522.8
ENST00000392329.7
ENST00000430311.5
INPP1
inositol polyphosphate-1-phosphatase
chr3_-_53844617 0.20 ENST00000481668.5
ENST00000467802.1
CHDH
choline dehydrogenase
chr16_-_72172135 0.20 ENST00000537465.5
ENST00000237353.15
PMFBP1
polyamine modulated factor 1 binding protein 1
chr1_-_23799561 0.19 ENST00000445705.1
GALE
UDP-galactose-4-epimerase
chr22_-_31662180 0.19 ENST00000435900.5
PISD
phosphatidylserine decarboxylase
chr5_-_79514127 0.19 ENST00000334082.11
HOMER1
homer scaffold protein 1
chr6_+_125219804 0.19 ENST00000524679.1
TPD52L1
TPD52 like 1
chr8_-_8893548 0.19 ENST00000276282.7
MFHAS1
malignant fibrous histiocytoma amplified sequence 1
chr7_-_20217342 0.18 ENST00000400331.10
ENST00000332878.8
MACC1
MET transcriptional regulator MACC1
chr12_-_52406335 0.18 ENST00000257974.3
KRT82
keratin 82
chr7_+_39623547 0.18 ENST00000005257.7
RALA
RAS like proto-oncogene A
chr17_-_29176752 0.18 ENST00000533112.5
MYO18A
myosin XVIIIA
chr11_-_95232514 0.18 ENST00000634898.1
ENST00000542176.1
ENST00000278499.6
SESN3
sestrin 3
chr14_-_23155302 0.18 ENST00000529705.6
SLC7A8
solute carrier family 7 member 8
chr2_+_28392802 0.18 ENST00000379619.5
ENST00000264716.9
FOSL2
FOS like 2, AP-1 transcription factor subunit
chr4_+_73740541 0.17 ENST00000401931.1
ENST00000307407.8
CXCL8
C-X-C motif chemokine ligand 8
chr1_-_23799533 0.17 ENST00000429356.5
GALE
UDP-galactose-4-epimerase
chr8_-_109975757 0.17 ENST00000524391.6
KCNV1
potassium voltage-gated channel modifier subfamily V member 1
chr11_-_2171805 0.17 ENST00000381178.5
ENST00000381175.5
ENST00000333684.9
ENST00000352909.8
TH
tyrosine hydroxylase
chr10_+_84328581 0.17 ENST00000359979.8
ENST00000372088.8
CCSER2
coiled-coil serine rich protein 2
chr6_+_159890964 0.16 ENST00000434562.2
ENST00000674077.2
ENSG00000236823.2
MAS1
novel transcript
MAS1 proto-oncogene, G protein-coupled receptor
chr9_+_100429511 0.16 ENST00000613183.1
MSANTD3
Myb/SANT DNA binding domain containing 3
chr2_+_169069537 0.16 ENST00000428522.5
ENST00000450153.1
ENST00000674881.1
ENST00000421653.5
DHRS9
dehydrogenase/reductase 9
chr17_-_81923532 0.16 ENST00000392366.7
MAFG
MAF bZIP transcription factor G
chr11_+_18599782 0.16 ENST00000634992.1
ENST00000635674.1
ENST00000511927.2
SPTY2D1OS
SPTY2D1 opposite strand
chr3_+_36380477 0.16 ENST00000457375.6
ENST00000273183.8
ENST00000434649.1
STAC
SH3 and cysteine rich domain
chr11_-_123885627 0.16 ENST00000528595.1
ENST00000375026.7
TMEM225
transmembrane protein 225
chr6_-_656963 0.15 ENST00000380907.2
HUS1B
HUS1 checkpoint clamp component B
chr7_+_112423137 0.15 ENST00000005558.8
ENST00000621379.4
IFRD1
interferon related developmental regulator 1
chr11_-_64246190 0.15 ENST00000392210.6
PPP1R14B
protein phosphatase 1 regulatory inhibitor subunit 14B
chr17_+_77319465 0.15 ENST00000329047.13
SEPTIN9
septin 9
chr6_+_30717433 0.15 ENST00000681435.1
TUBB
tubulin beta class I
chr15_+_40239042 0.15 ENST00000558055.5
ENST00000455577.6
PAK6
p21 (RAC1) activated kinase 6
chr6_+_63571702 0.15 ENST00000672924.1
PTP4A1
protein tyrosine phosphatase 4A1
chr1_+_36155930 0.14 ENST00000316156.8
MAP7D1
MAP7 domain containing 1
chr12_-_48957365 0.14 ENST00000398092.4
ENST00000539611.1
ENSG00000272822.2
ARF3
novel protein
ADP ribosylation factor 3
chr11_+_68903849 0.14 ENST00000675615.1
ENST00000255078.8
IGHMBP2
immunoglobulin mu DNA binding protein 2
chr8_-_42768602 0.14 ENST00000534622.5
CHRNA6
cholinergic receptor nicotinic alpha 6 subunit
chr17_-_75405486 0.14 ENST00000392562.5
GRB2
growth factor receptor bound protein 2
chr5_-_88731827 0.14 ENST00000627170.2
MEF2C
myocyte enhancer factor 2C
chr1_-_6602885 0.13 ENST00000377663.3
KLHL21
kelch like family member 21
chr12_-_95996302 0.13 ENST00000261208.8
ENST00000538703.5
ENST00000541929.5
HAL
histidine ammonia-lyase
chr17_+_48892761 0.13 ENST00000355938.9
ENST00000393366.7
ENST00000503641.5
ENST00000514808.5
ENST00000506855.1
ATP5MC1
ATP synthase membrane subunit c locus 1
chr15_+_40239420 0.13 ENST00000560346.5
PAK6
p21 (RAC1) activated kinase 6
chr9_+_98943705 0.13 ENST00000610452.1
COL15A1
collagen type XV alpha 1 chain
chr1_-_94541636 0.13 ENST00000370207.4
F3
coagulation factor III, tissue factor
chr20_+_43558968 0.13 ENST00000647834.1
ENST00000373100.7
ENST00000648083.1
ENST00000648530.1
SGK2
serum/glucocorticoid regulated kinase 2
chr1_+_36156096 0.13 ENST00000474796.2
ENST00000373150.8
ENST00000373151.6
MAP7D1
MAP7 domain containing 1
chr19_+_38899680 0.13 ENST00000576510.5
ENST00000392079.7
NFKBIB
NFKB inhibitor beta
chr22_+_22720615 0.13 ENST00000390309.2
IGLV3-19
immunoglobulin lambda variable 3-19
chr17_-_75405647 0.13 ENST00000316804.10
ENST00000316615.9
GRB2
growth factor receptor bound protein 2
chr1_-_6602859 0.13 ENST00000377658.8
KLHL21
kelch like family member 21
chr1_+_26863140 0.13 ENST00000339276.6
SFN
stratifin
chr5_+_66828762 0.13 ENST00000490016.6
ENST00000403666.5
ENST00000450827.5
MAST4
microtubule associated serine/threonine kinase family member 4
chr16_+_89921851 0.12 ENST00000554444.5
ENST00000556565.5
TUBB3
tubulin beta 3 class III
chr22_-_38755990 0.12 ENST00000405018.5
ENST00000438058.5
SUN2
Sad1 and UNC84 domain containing 2
chr9_-_74887720 0.12 ENST00000449912.6
TRPM6
transient receptor potential cation channel subfamily M member 6
chr1_-_94541746 0.12 ENST00000334047.12
F3
coagulation factor III, tissue factor
chrX_+_49171918 0.12 ENST00000376322.7
PLP2
proteolipid protein 2
chr22_-_38755458 0.12 ENST00000405510.5
ENST00000433561.5
SUN2
Sad1 and UNC84 domain containing 2
chr5_-_150086511 0.11 ENST00000675795.1
CSF1R
colony stimulating factor 1 receptor
chr5_+_54455661 0.11 ENST00000302005.3
HSPB3
heat shock protein family B (small) member 3
chr17_+_76738012 0.11 ENST00000590514.5
MFSD11
major facilitator superfamily domain containing 11
chr12_-_48957445 0.11 ENST00000541959.5
ENST00000447318.6
ENST00000256682.9
ARF3
ADP ribosylation factor 3
chr17_-_75154534 0.10 ENST00000356033.8
JPT1
Jupiter microtubule associated homolog 1
chr12_-_118190510 0.10 ENST00000540561.5
ENST00000537952.1
ENST00000537822.1
TAOK3
TAO kinase 3
chr4_+_70721953 0.10 ENST00000381006.8
ENST00000226328.8
RUFY3
RUN and FYVE domain containing 3
chr11_+_10456186 0.10 ENST00000528723.5
AMPD3
adenosine monophosphate deaminase 3
chr2_-_190062721 0.10 ENST00000260950.5
MSTN
myostatin
chr2_+_219572304 0.10 ENST00000243786.3
INHA
inhibin subunit alpha
chr17_-_29078857 0.10 ENST00000359450.6
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr15_+_75206398 0.10 ENST00000565074.1
C15orf39
chromosome 15 open reading frame 39
chr14_-_75069478 0.10 ENST00000555463.1
ACYP1
acylphosphatase 1
chr8_-_42768781 0.10 ENST00000276410.7
CHRNA6
cholinergic receptor nicotinic alpha 6 subunit
chr3_-_98522514 0.10 ENST00000503004.5
ENST00000506575.1
ENST00000513452.5
ENST00000515620.5
CLDND1
claudin domain containing 1
chr18_+_9885964 0.10 ENST00000357775.6
ENST00000306084.6
TXNDC2
thioredoxin domain containing 2
chr17_+_7440738 0.10 ENST00000575398.5
ENST00000575082.5
FGF11
fibroblast growth factor 11
chr6_-_38703066 0.09 ENST00000373365.5
GLO1
glyoxalase I
chr8_+_26293112 0.09 ENST00000523925.5
ENST00000315985.7
PPP2R2A
protein phosphatase 2 regulatory subunit Balpha
chr9_-_70414657 0.09 ENST00000377126.4
KLF9
Kruppel like factor 9
chr9_-_74887914 0.09 ENST00000360774.6
TRPM6
transient receptor potential cation channel subfamily M member 6
chr3_-_31981228 0.09 ENST00000396556.7
ENST00000438237.6
OSBPL10
oxysterol binding protein like 10
chr12_+_53299682 0.09 ENST00000267103.10
ENST00000548632.5
MYG1
MYG1 exonuclease
chr7_+_143222037 0.09 ENST00000408947.4
TAS2R40
taste 2 receptor member 40
chr3_-_149576203 0.09 ENST00000472417.1
WWTR1
WW domain containing transcription regulator 1
chr11_-_64245816 0.09 ENST00000542235.1
PPP1R14B
protein phosphatase 1 regulatory inhibitor subunit 14B
chr19_+_1407517 0.09 ENST00000336761.10
ENST00000233078.9
ENST00000592522.5
DAZAP1
DAZ associated protein 1
chr20_-_17558811 0.09 ENST00000536626.7
ENST00000377868.6
BFSP1
beaded filament structural protein 1
chr11_-_5516690 0.08 ENST00000380184.2
UBQLNL
ubiquilin like
chr11_+_128693887 0.08 ENST00000281428.12
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr4_+_168832005 0.08 ENST00000393726.7
ENST00000507735.6
PALLD
palladin, cytoskeletal associated protein
chr11_-_47185840 0.08 ENST00000539589.5
ENST00000528462.5
PACSIN3
protein kinase C and casein kinase substrate in neurons 3
chr3_-_169869833 0.08 ENST00000523069.1
ENST00000264676.9
ENST00000316428.10
LRRC31
leucine rich repeat containing 31
chr2_-_96035974 0.08 ENST00000434632.5
GPAT2
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr7_-_42237187 0.08 ENST00000395925.8
GLI3
GLI family zinc finger 3
chr8_-_27258414 0.07 ENST00000523048.5
STMN4
stathmin 4
chr2_-_169031317 0.07 ENST00000650372.1
ABCB11
ATP binding cassette subfamily B member 11
chr8_-_27258386 0.07 ENST00000350889.8
ENST00000519997.5
ENST00000519614.5
ENST00000522908.1
ENST00000265770.11
STMN4
stathmin 4
chr20_+_36154630 0.07 ENST00000338074.7
ENST00000636016.2
ENST00000373945.5
EPB41L1
erythrocyte membrane protein band 4.1 like 1
chr7_-_32070396 0.07 ENST00000396191.6
PDE1C
phosphodiesterase 1C
chr3_+_148730100 0.07 ENST00000474935.5
ENST00000475347.5
ENST00000461609.1
AGTR1
angiotensin II receptor type 1
chr9_-_35112379 0.07 ENST00000488109.6
FAM214B
family with sequence similarity 214 member B

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.5 2.3 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.4 2.2 GO:0007296 vitellogenesis(GO:0007296)
0.3 1.3 GO:1903575 cornified envelope assembly(GO:1903575)
0.3 1.3 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.2 1.2 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.2 0.6 GO:0046521 sphingoid catabolic process(GO:0046521)
0.2 0.5 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.1 0.3 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.3 GO:1902728 positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.1 0.3 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.1 0.3 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.1 5.1 GO:0018149 peptide cross-linking(GO:0018149)
0.1 2.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.2 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.1 1.2 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 0.3 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 1.2 GO:0051546 keratinocyte migration(GO:0051546)
0.1 0.2 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.1 0.2 GO:1903028 positive regulation of opsonization(GO:1903028)
0.1 0.2 GO:0052314 phthalate metabolic process(GO:0018963) epinephrine biosynthetic process(GO:0042418) phytoalexin metabolic process(GO:0052314)
0.1 0.8 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.1 0.7 GO:0035092 sperm chromatin condensation(GO:0035092)
0.1 0.2 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.1 0.1 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.1 0.2 GO:0007518 myoblast fate determination(GO:0007518)
0.0 0.2 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.2 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.0 0.3 GO:0061743 motor learning(GO:0061743)
0.0 0.3 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.8 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.2 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.3 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0 0.4 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.2 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.4 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 1.0 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.1 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.2 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.1 GO:0060873 subpallium cell proliferation in forebrain(GO:0022012) lateral ganglionic eminence cell proliferation(GO:0022018) lambdoid suture morphogenesis(GO:0060366) sagittal suture morphogenesis(GO:0060367) anterior semicircular canal development(GO:0060873) lateral semicircular canal development(GO:0060875)
0.0 0.1 GO:0045578 negative regulation of B cell differentiation(GO:0045578) negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0 0.2 GO:0015886 heme transport(GO:0015886)
0.0 0.4 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.5 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.5 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.4 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 2.1 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.4 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.2 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.1 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.1 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.2 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.0 0.1 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.2 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.3 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.2 GO:0051665 membrane raft localization(GO:0051665)
0.0 0.1 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.0 0.1 GO:0051414 response to cortisol(GO:0051414)
0.0 0.1 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.4 GO:0060512 prostate gland morphogenesis(GO:0060512)
0.0 0.0 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.4 GO:0005980 glycogen catabolic process(GO:0005980)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.9 GO:0005610 laminin-5 complex(GO:0005610)
0.2 1.0 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.4 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.8 GO:0097149 centralspindlin complex(GO:0097149)
0.1 1.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 7.4 GO:0001533 cornified envelope(GO:0001533)
0.1 1.0 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 2.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.3 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.3 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.1 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 0.3 GO:0005827 polar microtubule(GO:0005827)
0.0 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 0.3 GO:0005638 lamin filament(GO:0005638)
0.0 0.3 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.4 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.2 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.3 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.4 GO:0042599 lamellar body(GO:0042599)
0.0 0.4 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.3 GO:0032433 filopodium tip(GO:0032433)
0.0 1.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.1 GO:0035363 histone locus body(GO:0035363)
0.0 0.2 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0032797 SMN complex(GO:0032797)
0.0 2.0 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.1 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.0 1.8 GO:0005882 intermediate filament(GO:0005882)
0.0 0.3 GO:0048786 presynaptic active zone(GO:0048786)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.8 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.5 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 1.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.4 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.1 0.4 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.1 1.0 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.5 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.6 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.2 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.1 0.3 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 0.2 GO:0031755 endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
0.1 2.3 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.2 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 0.2 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.0 0.2 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.4 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.0 0.3 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.4 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.0 0.3 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.4 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.4 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.3 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.2 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity(GO:0008441)
0.0 0.2 GO:0034617 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714) tetrahydrobiopterin binding(GO:0034617)
0.0 0.1 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.3 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.2 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 2.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 1.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.2 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 5.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 2.2 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.7 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.6 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 1.4 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 4.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.9 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.8 PID AURORA B PATHWAY Aurora B signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 1.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.8 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 2.5 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.7 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac