ISMARA results: FOSL2

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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for FOSL2_SMARCC1

Z-value: 2.04

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Transcription factors associated with FOSL2_SMARCC1

Gene Symbol	Gene ID	Gene Info
FOSL2 Ensembl NCBI GeneCards UniProt	ENSG00000075426.12	FOSL2
SMARCC1 Ensembl NCBI GeneCards UniProt	ENSG00000173473.11	SMARCC1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
FOSL2	hg38_v1_chr2_+_28395511_28395743	0.81	5.9e-08	Click!
SMARCC1	hg38_v1_chr3_-_47781837_47781908	-0.38	4.1e-02	Click!

Activity profile of FOSL2_SMARCC1 motif

Sorted Z-values of FOSL2_SMARCC1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FOSL2_SMARCC1

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View png image

Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr18_+_23873000 Show fit	23.17	ENST00000269217.11 ENST00000587184.5	LAMA3 Ensembl NCBI GeneCards UniProt Show fit	laminin subunit alpha 3
chr1_+_150508074 Show fit	20.83	ENST00000369049.8	ECM1 Ensembl NCBI GeneCards UniProt Show fit	extracellular matrix protein 1
chr1_+_150508099 Show fit	20.71	ENST00000346569.6 ENST00000369047.9	ECM1 Ensembl NCBI GeneCards UniProt Show fit	extracellular matrix protein 1
chr19_-_35528221 Show fit	20.34	ENST00000588674.5 ENST00000452271.7 ENST00000518157.1	SBSN Ensembl NCBI GeneCards UniProt Show fit	suprabasin
chr17_-_41612757 Show fit	15.68	ENST00000301653.9 ENST00000593067.1	KRT16 Ensembl NCBI GeneCards UniProt Show fit	keratin 16
chr1_-_153549120 Show fit	12.37	ENST00000368712.1	S100A3 Ensembl NCBI GeneCards UniProt Show fit	S100 calcium binding protein A3
chr2_+_113117889 Show fit	11.71	ENST00000361779.7 ENST00000259206.9 ENST00000354115.6	IL1RN Ensembl NCBI GeneCards UniProt Show fit	interleukin 1 receptor antagonist
chr1_-_153057504 Show fit	10.45	ENST00000392653.3	SPRR2A Ensembl NCBI GeneCards UniProt Show fit	small proline rich protein 2A
chr6_+_73695779 Show fit	10.14	ENST00000422508.6 ENST00000437994.6	CD109 Ensembl NCBI GeneCards UniProt Show fit	CD109 molecule
chr6_+_73696145 Show fit	9.97	ENST00000287097.6	CD109 Ensembl NCBI GeneCards UniProt Show fit	CD109 molecule
chr1_-_153549238 Show fit	9.90	ENST00000368713.8	S100A3 Ensembl NCBI GeneCards UniProt Show fit	S100 calcium binding protein A3
chr1_-_153094521 Show fit	9.37	ENST00000368750.8	SPRR2E Ensembl NCBI GeneCards UniProt Show fit	small proline rich protein 2E
chr11_-_65900375 Show fit	9.34	ENST00000312562.7	FOSL1 Ensembl NCBI GeneCards UniProt Show fit	FOS like 1, AP-1 transcription factor subunit
chr12_-_121800558 Show fit	9.33	ENST00000546227.5	RHOF Ensembl NCBI GeneCards UniProt Show fit	ras homolog family member F, filopodia associated
chr19_-_50969567 Show fit	8.93	ENST00000310157.7	KLK6 Ensembl NCBI GeneCards UniProt Show fit	kallikrein related peptidase 6
chr12_+_53098846 Show fit	8.68	ENST00000650247.1 ENST00000549628.1	IGFBP6 Ensembl NCBI GeneCards UniProt Show fit	insulin like growth factor binding protein 6
chr12_-_119804298 Show fit	8.39	ENST00000678652.1 ENST00000678494.1	CIT Ensembl NCBI GeneCards UniProt Show fit	citron rho-interacting serine/threonine kinase
chr12_-_119804472 Show fit	8.39	ENST00000678087.1 ENST00000677993.1	CIT Ensembl NCBI GeneCards UniProt Show fit	citron rho-interacting serine/threonine kinase
chr15_-_74212219 Show fit	8.31	ENST00000449139.6	STRA6 Ensembl NCBI GeneCards UniProt Show fit	signaling receptor and transporter of retinol STRA6
chr11_-_65900413 Show fit	8.10	ENST00000448083.6 ENST00000531493.5 ENST00000532401.1	FOSL1 Ensembl NCBI GeneCards UniProt Show fit	FOS like 1, AP-1 transcription factor subunit
chr6_+_47698538 Show fit	7.44	ENST00000327753.7	ADGRF4 Ensembl NCBI GeneCards UniProt Show fit	adhesion G protein-coupled receptor F4
chr18_+_63775395 Show fit	7.39	ENST00000398019.7	SERPINB7 Ensembl NCBI GeneCards UniProt Show fit	serpin family B member 7
chr6_+_47698574 Show fit	7.30	ENST00000283303.3	ADGRF4 Ensembl NCBI GeneCards UniProt Show fit	adhesion G protein-coupled receptor F4
chr18_+_63775369 Show fit	7.26	ENST00000540675.5	SERPINB7 Ensembl NCBI GeneCards UniProt Show fit	serpin family B member 7
chr12_-_95116967 Show fit	6.92	ENST00000551521.5	FGD6 Ensembl NCBI GeneCards UniProt Show fit	FYVE, RhoGEF and PH domain containing 6
chr1_-_153113507 Show fit	6.87	ENST00000468739.2	SPRR2F Ensembl NCBI GeneCards UniProt Show fit	small proline rich protein 2F
chr18_+_36544544 Show fit	6.80	ENST00000591635.5	FHOD3 Ensembl NCBI GeneCards UniProt Show fit	formin homology 2 domain containing 3
chr11_-_62556230 Show fit	6.75	ENST00000530285.5	AHNAK Ensembl NCBI GeneCards UniProt Show fit	AHNAK nucleoprotein
chr3_-_48595267 Show fit	6.65	ENST00000328333.12 ENST00000681320.1	COL7A1 Ensembl NCBI GeneCards UniProt Show fit	collagen type VII alpha 1 chain
chr9_+_137225166 Show fit	6.55	ENST00000650725.2	CYSRT1 Ensembl NCBI GeneCards UniProt Show fit	cysteine rich tail 1
chr5_-_177496845 Show fit	6.50	ENST00000506537.1	PDLIM7 Ensembl NCBI GeneCards UniProt Show fit	PDZ and LIM domain 7
chr7_+_48088596 Show fit	6.42	ENST00000416681.5 ENST00000331803.8 ENST00000432131.5	UPP1 Ensembl NCBI GeneCards UniProt Show fit	uridine phosphorylase 1
chr12_+_13196718 Show fit	6.22	ENST00000431267.2 ENST00000542474.5 ENST00000544053.5 ENST00000256951.10	EMP1 Ensembl NCBI GeneCards UniProt Show fit	epithelial membrane protein 1
chr5_-_177496802 Show fit	6.08	ENST00000506161.5	PDLIM7 Ensembl NCBI GeneCards UniProt Show fit	PDZ and LIM domain 7
chr11_-_6320494 Show fit	5.93	ENST00000303927.4 ENST00000530979.1	CAVIN3 Ensembl NCBI GeneCards UniProt Show fit	caveolae associated protein 3
chr21_-_26843012 Show fit	5.89	ENST00000517777.6	ADAMTS1 Ensembl NCBI GeneCards UniProt Show fit	ADAM metallopeptidase with thrombospondin type 1 motif 1
chr19_-_35501878 Show fit	5.80	ENST00000593342.5 ENST00000601650.1 ENST00000408915.6	DMKN Ensembl NCBI GeneCards UniProt Show fit	dermokine
chr21_-_26843063 Show fit	5.75	ENST00000678221.1	ADAMTS1 Ensembl NCBI GeneCards UniProt Show fit	ADAM metallopeptidase with thrombospondin type 1 motif 1
chr19_-_51034840 Show fit	5.71	ENST00000529888.5	KLK12 Ensembl NCBI GeneCards UniProt Show fit	kallikrein related peptidase 12
chr12_-_94616061 Show fit	5.62	ENST00000551457.1	TMCC3 Ensembl NCBI GeneCards UniProt Show fit	transmembrane and coiled-coil domain family 3
chr19_-_51034892 Show fit	5.61	ENST00000319590.8 ENST00000250351.4	KLK12 Ensembl NCBI GeneCards UniProt Show fit	kallikrein related peptidase 12
chr17_+_4950147 Show fit	5.59	ENST00000522301.5	ENO3 Ensembl NCBI GeneCards UniProt Show fit	enolase 3
chr10_+_17228215 Show fit	5.54	ENST00000544301.7	VIM Ensembl NCBI GeneCards UniProt Show fit	vimentin
chr20_-_653189 Show fit	5.49	ENST00000381962.4	SRXN1 Ensembl NCBI GeneCards UniProt Show fit	sulfiredoxin 1
chr8_+_10672623 Show fit	5.32	ENST00000304519.10	C8orf74 Ensembl NCBI GeneCards UniProt Show fit	chromosome 8 open reading frame 74
chr11_-_66336396 Show fit	5.32	ENST00000627248.1 ENST00000311320.9	RIN1 Ensembl NCBI GeneCards UniProt Show fit	Ras and Rab interactor 1
chr19_-_51034993 Show fit	5.30	ENST00000684732.1	KLK12 Ensembl NCBI GeneCards UniProt Show fit	kallikrein related peptidase 12
chr5_+_136059151 Show fit	5.29	ENST00000503087.1	TGFBI Ensembl NCBI GeneCards UniProt Show fit	transforming growth factor beta induced
chr19_-_35513641 Show fit	5.26	ENST00000339686.8 ENST00000447113.6	DMKN Ensembl NCBI GeneCards UniProt Show fit	dermokine
chr7_+_143381286 Show fit	5.22	ENST00000449630.5 ENST00000322764.10 ENST00000457235.5	ZYX Ensembl NCBI GeneCards UniProt Show fit	zyxin
chr13_+_77535681 Show fit	5.15	ENST00000349847.4	SCEL Ensembl NCBI GeneCards UniProt Show fit	sciellin
chr13_+_77535742 Show fit	5.12	ENST00000377246.7	SCEL Ensembl NCBI GeneCards UniProt Show fit	sciellin
chr13_+_77535669 Show fit	5.10	ENST00000535157.5	SCEL Ensembl NCBI GeneCards UniProt Show fit	sciellin
chr11_-_102798148 Show fit	4.94	ENST00000315274.7	MMP1 Ensembl NCBI GeneCards UniProt Show fit	matrix metallopeptidase 1
chr19_+_38789198 Show fit	4.84	ENST00000314980.5	LGALS7B Ensembl NCBI GeneCards UniProt Show fit	galectin 7B
chr1_+_154405326 Show fit	4.77	ENST00000368485.8	IL6R Ensembl NCBI GeneCards UniProt Show fit	interleukin 6 receptor
chr19_-_51020154 Show fit	4.71	ENST00000391805.5 ENST00000599077.1	KLK10 Ensembl NCBI GeneCards UniProt Show fit	kallikrein related peptidase 10
chr5_+_150497772 Show fit	4.69	ENST00000523767.5	NDST1 Ensembl NCBI GeneCards UniProt Show fit	N-deacetylase and N-sulfotransferase 1
chr1_+_183186238 Show fit	4.66	ENST00000493293.5 ENST00000264144.5	LAMC2 Ensembl NCBI GeneCards UniProt Show fit	laminin subunit gamma 2
chr20_+_35172046 Show fit	4.60	ENST00000216968.5	PROCR Ensembl NCBI GeneCards UniProt Show fit	protein C receptor
chr17_-_42423246 Show fit	4.58	ENST00000357037.6	CAVIN1 Ensembl NCBI GeneCards UniProt Show fit	caveolae associated protein 1
chr2_-_112784486 Show fit	4.53	ENST00000263339.4	IL1A Ensembl NCBI GeneCards UniProt Show fit	interleukin 1 alpha
chr16_-_30113528 Show fit	4.52	ENST00000406256.8	GDPD3 Ensembl NCBI GeneCards UniProt Show fit	glycerophosphodiester phosphodiesterase domain containing 3
chr15_+_67128103 Show fit	4.43	ENST00000558894.5	SMAD3 Ensembl NCBI GeneCards UniProt Show fit	SMAD family member 3
chr20_+_37383648 Show fit	4.24	ENST00000373567.6	SRC Ensembl NCBI GeneCards UniProt Show fit	SRC proto-oncogene, non-receptor tyrosine kinase
chr3_-_98522514 Show fit	4.14	ENST00000503004.5 ENST00000506575.1 ENST00000513452.5 ENST00000515620.5	CLDND1 Ensembl NCBI GeneCards UniProt Show fit	claudin domain containing 1
chr1_-_204151884 Show fit	4.11	ENST00000367201.7	ETNK2 Ensembl NCBI GeneCards UniProt Show fit	ethanolamine kinase 2
chr9_+_35673917 Show fit	4.06	ENST00000617161.1 ENST00000378357.9	CA9 Ensembl NCBI GeneCards UniProt Show fit	carbonic anhydrase 9
chr1_+_154405193 Show fit	4.05	ENST00000622330.4 ENST00000344086.8	IL6R Ensembl NCBI GeneCards UniProt Show fit	interleukin 6 receptor
chr19_-_51020019 Show fit	3.89	ENST00000309958.7	KLK10 Ensembl NCBI GeneCards UniProt Show fit	kallikrein related peptidase 10
chr6_+_41637005 Show fit	3.81	ENST00000419164.6 ENST00000373051.6	MDFI Ensembl NCBI GeneCards UniProt Show fit	MyoD family inhibitor
chr15_-_74212256 Show fit	3.80	ENST00000416286.7	STRA6 Ensembl NCBI GeneCards UniProt Show fit	signaling receptor and transporter of retinol STRA6
chrX_+_136169624 Show fit	3.79	ENST00000394153.6	FHL1 Ensembl NCBI GeneCards UniProt Show fit	four and a half LIM domains 1
chr1_-_204152010 Show fit	3.69	ENST00000367202.9	ETNK2 Ensembl NCBI GeneCards UniProt Show fit	ethanolamine kinase 2
chrX_+_136169833 Show fit	3.68	ENST00000628032.2	FHL1 Ensembl NCBI GeneCards UniProt Show fit	four and a half LIM domains 1
chr1_-_159954213 Show fit	3.63	ENST00000368092.7 ENST00000368093.4	SLAMF9 Ensembl NCBI GeneCards UniProt Show fit	SLAM family member 9
chr15_-_79971164 Show fit	3.61	ENST00000335661.6 ENST00000267953.4 ENST00000677151.1	BCL2A1 Ensembl NCBI GeneCards UniProt Show fit	BCL2 related protein A1
chr7_-_108003122 Show fit	3.56	ENST00000393559.2 ENST00000222399.11 ENST00000676777.1 ENST00000439976.6 ENST00000393560.5 ENST00000677793.1 ENST00000679244.1	LAMB1 Ensembl NCBI GeneCards UniProt Show fit	laminin subunit beta 1
chr17_+_76385256 Show fit	3.56	ENST00000392496.3	SPHK1 Ensembl NCBI GeneCards UniProt Show fit	sphingosine kinase 1
chr19_-_43781249 Show fit	3.48	ENST00000615047.4	KCNN4 Ensembl NCBI GeneCards UniProt Show fit	potassium calcium-activated channel subfamily N member 4
chr1_-_28193873 Show fit	3.48	ENST00000305392.3 ENST00000539896.1	PTAFR Ensembl NCBI GeneCards UniProt Show fit	platelet activating factor receptor
chr18_+_63777773 Show fit	3.46	ENST00000447428.5 ENST00000546027.5	SERPINB7 Ensembl NCBI GeneCards UniProt Show fit	serpin family B member 7
chr15_+_67166019 Show fit	3.45	ENST00000537194.6	SMAD3 Ensembl NCBI GeneCards UniProt Show fit	SMAD family member 3
chrX_+_136169664 Show fit	3.43	ENST00000456445.5	FHL1 Ensembl NCBI GeneCards UniProt Show fit	four and a half LIM domains 1
chr1_+_26280117 Show fit	3.43	ENST00000319041.6	SH3BGRL3 Ensembl NCBI GeneCards UniProt Show fit	SH3 domain binding glutamate rich protein like 3
chr1_-_156705575 Show fit	3.42	ENST00000368222.8	CRABP2 Ensembl NCBI GeneCards UniProt Show fit	cellular retinoic acid binding protein 2
chr17_-_7590072 Show fit	3.42	ENST00000538513.6 ENST00000570788.1 ENST00000250055.3	SOX15 Ensembl NCBI GeneCards UniProt Show fit	SRY-box transcription factor 15
chr16_+_58500135 Show fit	3.39	ENST00000563978.5 ENST00000569923.5 ENST00000356752.8 ENST00000563799.5 ENST00000562999.5 ENST00000570248.5 ENST00000562731.5 ENST00000568424.1	NDRG4 Ensembl NCBI GeneCards UniProt Show fit	NDRG family member 4
chr10_-_88851809 Show fit	3.37	ENST00000371930.5	ANKRD22 Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat domain 22
chr4_-_39032343 Show fit	3.37	ENST00000381938.4	TMEM156 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 156
chr19_-_43780957 Show fit	3.35	ENST00000648319.1	KCNN4 Ensembl NCBI GeneCards UniProt Show fit	potassium calcium-activated channel subfamily N member 4
chr19_-_51065067 Show fit	3.33	ENST00000595547.5 ENST00000335422.3 ENST00000595793.6 ENST00000596955.1	KLK13 Ensembl NCBI GeneCards UniProt Show fit	kallikrein related peptidase 13
chr19_-_43670153 Show fit	3.33	ENST00000601723.5 ENST00000339082.7 ENST00000340093.8	PLAUR Ensembl NCBI GeneCards UniProt Show fit	plasminogen activator, urokinase receptor
chr3_+_191329020 Show fit	3.31	ENST00000392456.4	CCDC50 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 50
chr20_+_46008900 Show fit	3.22	ENST00000372330.3	MMP9 Ensembl NCBI GeneCards UniProt Show fit	matrix metallopeptidase 9
chr7_+_26291850 Show fit	3.14	ENST00000338523.9 ENST00000446848.6	SNX10 Ensembl NCBI GeneCards UniProt Show fit	sorting nexin 10
chr4_+_73740541 Show fit	3.13	ENST00000401931.1 ENST00000307407.8	CXCL8 Ensembl NCBI GeneCards UniProt Show fit	C-X-C motif chemokine ligand 8
chr18_+_58671517 Show fit	3.13	ENST00000345724.7	MALT1 Ensembl NCBI GeneCards UniProt Show fit	MALT1 paracaspase
chr9_-_35112379 Show fit	3.12	ENST00000488109.6	FAM214B Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 214 member B
chr16_+_50266530 Show fit	3.12	ENST00000566433.6 ENST00000394697.7 ENST00000673801.1	ADCY7 Ensembl NCBI GeneCards UniProt Show fit	adenylate cyclase 7
chr12_-_48865863 Show fit	3.02	ENST00000309739.6	RND1 Ensembl NCBI GeneCards UniProt Show fit	Rho family GTPase 1
chr2_+_90021567 Show fit	3.01	ENST00000436451.2	IGKV6D-21 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 6D-21 (non-functional)
chr12_-_47758828 Show fit	2.94	ENST00000389212.7 ENST00000449771.7	RAPGEF3 Ensembl NCBI GeneCards UniProt Show fit	Rap guanine nucleotide exchange factor 3
chrX_+_100644183 Show fit	2.92	ENST00000640889.1 ENST00000373004.5	SRPX2 Ensembl NCBI GeneCards UniProt Show fit	sushi repeat containing protein X-linked 2
chr8_-_142614469 Show fit	2.92	ENST00000356613.4	ARC Ensembl NCBI GeneCards UniProt Show fit	activity regulated cytoskeleton associated protein
chr11_+_62881686 Show fit	2.90	ENST00000536981.6 ENST00000539891.6	SLC3A2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 3 member 2
chr6_-_35921047 Show fit	2.82	ENST00000361690.7 ENST00000512445.5	SRPK1 Ensembl NCBI GeneCards UniProt Show fit	SRSF protein kinase 1
chr3_-_12759224 Show fit	2.80	ENST00000314124.12 ENST00000435218.6 ENST00000435575.5	TMEM40 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 40
chr19_-_43198079 Show fit	2.80	ENST00000597374.5 ENST00000599371.1	PSG4 Ensembl NCBI GeneCards UniProt Show fit	pregnancy specific beta-1-glycoprotein 4
chrX_+_49171889 Show fit	2.78	ENST00000376327.6	PLP2 Ensembl NCBI GeneCards UniProt Show fit	proteolipid protein 2
chr11_-_64246190 Show fit	2.77	ENST00000392210.6	PPP1R14B Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1 regulatory inhibitor subunit 14B
chr17_-_29176752 Show fit	2.76	ENST00000533112.5	MYO18A Ensembl NCBI GeneCards UniProt Show fit	myosin XVIIIA
chr6_+_106098933 Show fit	2.75	ENST00000369089.3	PRDM1 Ensembl NCBI GeneCards UniProt Show fit	PR/SET domain 1
chr15_+_67125707 Show fit	2.75	ENST00000540846.6	SMAD3 Ensembl NCBI GeneCards UniProt Show fit	SMAD family member 3
chrX_+_136169891 Show fit	2.70	ENST00000449474.5	FHL1 Ensembl NCBI GeneCards UniProt Show fit	four and a half LIM domains 1
chr16_-_72620 Show fit	2.69	ENST00000262316.10	RHBDF1 Ensembl NCBI GeneCards UniProt Show fit	rhomboid 5 homolog 1
chr6_+_32153441 Show fit	2.68	ENST00000414204.5 ENST00000361568.6 ENST00000395523.5	PPT2 Ensembl NCBI GeneCards UniProt Show fit	palmitoyl-protein thioesterase 2
chr8_+_86098901 Show fit	2.66	ENST00000285393.4	ATP6V0D2 Ensembl NCBI GeneCards UniProt Show fit	ATPase H+ transporting V0 subunit d2
chr8_+_125430333 Show fit	2.62	ENST00000311922.4	TRIB1 Ensembl NCBI GeneCards UniProt Show fit	tribbles pseudokinase 1
chr19_-_38773432 Show fit	2.61	ENST00000599035.1 ENST00000378626.5	LGALS7 Ensembl NCBI GeneCards UniProt Show fit	galectin 7
chr9_-_107489754 Show fit	2.59	ENST00000610832.1 ENST00000374672.5	KLF4 Ensembl NCBI GeneCards UniProt Show fit	Kruppel like factor 4
chr17_+_7579491 Show fit	2.56	ENST00000380498.10 ENST00000584502.1 ENST00000250092.11	CD68 Ensembl NCBI GeneCards UniProt Show fit	CD68 molecule
chr1_+_156126160 Show fit	2.53	ENST00000448611.6 ENST00000368297.5	LMNA Ensembl NCBI GeneCards UniProt Show fit	lamin A/C
chr2_+_90069662 Show fit	2.53	ENST00000390271.2	IGKV6D-41 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 6D-41 (non-functional)
chr5_+_136058849 Show fit	2.53	ENST00000508076.5	TGFBI Ensembl NCBI GeneCards UniProt Show fit	transforming growth factor beta induced
chr11_+_844406 Show fit	2.49	ENST00000397404.5	TSPAN4 Ensembl NCBI GeneCards UniProt Show fit	tetraspanin 4
chr4_-_39032922 Show fit	2.47	ENST00000344606.6	TMEM156 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 156
chr17_+_75721327 Show fit	2.45	ENST00000579662.5	ITGB4 Ensembl NCBI GeneCards UniProt Show fit	integrin subunit beta 4
chr11_+_35176696 Show fit	2.39	ENST00000528455.5	CD44 Ensembl NCBI GeneCards UniProt Show fit	CD44 molecule (Indian blood group)
chr1_+_154325512 Show fit	2.39	ENST00000368489.6 ENST00000368487.7	ATP8B2 Ensembl NCBI GeneCards UniProt Show fit	ATPase phospholipid transporting 8B2
chr6_-_35921079 Show fit	2.38	ENST00000507909.1 ENST00000373825.7	SRPK1 Ensembl NCBI GeneCards UniProt Show fit	SRSF protein kinase 1
chr4_-_174522791 Show fit	2.38	ENST00000541923.5 ENST00000542498.5	HPGD Ensembl NCBI GeneCards UniProt Show fit	15-hydroxyprostaglandin dehydrogenase
chr11_+_35618450 Show fit	2.38	ENST00000317811.6	FJX1 Ensembl NCBI GeneCards UniProt Show fit	four-jointed box kinase 1
chr10_+_73911104 Show fit	2.37	ENST00000446342.5 ENST00000372764.4	PLAU Ensembl NCBI GeneCards UniProt Show fit	plasminogen activator, urokinase
chr6_-_130956371 Show fit	2.36	ENST00000639623.1 ENST00000525193.5 ENST00000527659.5	EPB41L2 Ensembl NCBI GeneCards UniProt Show fit	erythrocyte membrane protein band 4.1 like 2
chr18_+_54828406 Show fit	2.35	ENST00000262094.10	RAB27B Ensembl NCBI GeneCards UniProt Show fit	RAB27B, member RAS oncogene family
chr6_-_35921128 Show fit	2.35	ENST00000510290.5 ENST00000423325.6	SRPK1 Ensembl NCBI GeneCards UniProt Show fit	SRSF protein kinase 1
chrX_-_15664798 Show fit	2.32	ENST00000380342.4	CLTRN Ensembl NCBI GeneCards UniProt Show fit	collectrin, amino acid transport regulator
chr11_+_394196 Show fit	2.30	ENST00000331563.7 ENST00000531857.1	PKP3 Ensembl NCBI GeneCards UniProt Show fit	plakophilin 3
chr17_+_75721471 Show fit	2.30	ENST00000450894.7	ITGB4 Ensembl NCBI GeneCards UniProt Show fit	integrin subunit beta 4
chr18_+_63587336 Show fit	2.30	ENST00000344731.10	SERPINB13 Ensembl NCBI GeneCards UniProt Show fit	serpin family B member 13
chr9_-_35685462 Show fit	2.29	ENST00000607559.1	TPM2 Ensembl NCBI GeneCards UniProt Show fit	tropomyosin 2
chr11_+_73289403 Show fit	2.26	ENST00000535931.2 ENST00000544437.6	P2RY6 Ensembl NCBI GeneCards UniProt Show fit	pyrimidinergic receptor P2Y6
chr7_+_134843884 Show fit	2.24	ENST00000445569.6	CALD1 Ensembl NCBI GeneCards UniProt Show fit	caldesmon 1
chr12_-_76084612 Show fit	2.23	ENST00000535020.6 ENST00000552342.5	NAP1L1 Ensembl NCBI GeneCards UniProt Show fit	nucleosome assembly protein 1 like 1
chr11_-_118264445 Show fit	2.19	ENST00000438295.2	MPZL2 Ensembl NCBI GeneCards UniProt Show fit	myelin protein zero like 2
chr22_-_32159301 Show fit	2.18	ENST00000382097.4	C22orf42 Ensembl NCBI GeneCards UniProt Show fit	chromosome 22 open reading frame 42
chr7_+_130293134 Show fit	2.18	ENST00000445470.6 ENST00000492072.5 ENST00000222482.10 ENST00000473956.5 ENST00000493259.5 ENST00000486598.1	CPA4 Ensembl NCBI GeneCards UniProt Show fit	carboxypeptidase A4
chr1_-_150235972 Show fit	2.17	ENST00000534220.1	ANP32E Ensembl NCBI GeneCards UniProt Show fit	acidic nuclear phosphoprotein 32 family member E
chr12_-_57520480 Show fit	2.16	ENST00000642841.1 ENST00000547303.5 ENST00000552740.5 ENST00000547526.1 ENST00000346473.8 ENST00000551116.5	ENSG00000285133.1 Ensembl NCBI GeneCards UniProt Show fit DDIT3 Ensembl NCBI GeneCards UniProt Show fit	novel protein DNA damage inducible transcript 3
chr20_-_1329131 Show fit	2.11	ENST00000360779.4	SDCBP2 Ensembl NCBI GeneCards UniProt Show fit	syndecan binding protein 2
chr11_+_35176575 Show fit	2.09	ENST00000526000.6	CD44 Ensembl NCBI GeneCards UniProt Show fit	CD44 molecule (Indian blood group)
chr3_+_11137093 Show fit	2.08	ENST00000438284.2	HRH1 Ensembl NCBI GeneCards UniProt Show fit	histamine receptor H1
chr2_+_219627650 Show fit	2.06	ENST00000317151.7	SLC4A3 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 4 member 3
chr16_+_58500047 Show fit	2.05	ENST00000566192.5 ENST00000565088.5 ENST00000568640.5	NDRG4 Ensembl NCBI GeneCards UniProt Show fit	NDRG family member 4
chr2_+_190927649 Show fit	2.03	ENST00000409428.5 ENST00000409215.5	GLS Ensembl NCBI GeneCards UniProt Show fit	glutaminase
chr11_+_35176639 Show fit	2.03	ENST00000527889.6	CD44 Ensembl NCBI GeneCards UniProt Show fit	CD44 molecule (Indian blood group)
chr9_-_127578989 Show fit	2.03	ENST00000373314.7	NIBAN2 Ensembl NCBI GeneCards UniProt Show fit	niban apoptosis regulator 2
chr22_-_37188281 Show fit	2.03	ENST00000397110.6	C1QTNF6 Ensembl NCBI GeneCards UniProt Show fit	C1q and TNF related 6
chr5_-_177497561 Show fit	2.02	ENST00000359895.6 ENST00000355572.6 ENST00000393551.5 ENST00000505074.5 ENST00000393546.8 ENST00000355841.7	PDLIM7 Ensembl NCBI GeneCards UniProt Show fit	PDZ and LIM domain 7
chr11_+_35176611 Show fit	2.02	ENST00000279452.10	CD44 Ensembl NCBI GeneCards UniProt Show fit	CD44 molecule (Indian blood group)
chr2_+_219627565 Show fit	2.01	ENST00000273063.10	SLC4A3 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 4 member 3
chr1_-_151992571 Show fit	2.01	ENST00000368809.1	S100A10 Ensembl NCBI GeneCards UniProt Show fit	S100 calcium binding protein A10
chr3_-_149377637 Show fit	1.99	ENST00000305366.8	TM4SF1 Ensembl NCBI GeneCards UniProt Show fit	transmembrane 4 L six family member 1
chr8_-_67746348 Show fit	1.97	ENST00000297770.10	CPA6 Ensembl NCBI GeneCards UniProt Show fit	carboxypeptidase A6
chr2_+_219627622 Show fit	1.97	ENST00000358055.8	SLC4A3 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 4 member 3
chr11_-_82997477 Show fit	1.94	ENST00000534301.5	RAB30 Ensembl NCBI GeneCards UniProt Show fit	RAB30, member RAS oncogene family
chr1_+_36155930 Show fit	1.90	ENST00000316156.8	MAP7D1 Ensembl NCBI GeneCards UniProt Show fit	MAP7 domain containing 1
chr6_-_30744537 Show fit	1.89	ENST00000259874.6 ENST00000376377.2	IER3 Ensembl NCBI GeneCards UniProt Show fit	immediate early response 3
chr1_-_243843164 Show fit	1.89	ENST00000491219.6 ENST00000680056.1 ENST00000492957.2	AKT3 Ensembl NCBI GeneCards UniProt Show fit	AKT serine/threonine kinase 3
chr3_+_155080088 Show fit	1.89	ENST00000462745.5	MME Ensembl NCBI GeneCards UniProt Show fit	membrane metalloendopeptidase
chr3_+_172754457 Show fit	1.89	ENST00000441497.6	ECT2 Ensembl NCBI GeneCards UniProt Show fit	epithelial cell transforming 2
chr17_-_19004727 Show fit	1.86	ENST00000388995.11	FAM83G Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 83 member G
chr2_-_89160329 Show fit	1.85	ENST00000390256.2	IGKV6-21 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 6-21 (non-functional)
chr18_+_24155938 Show fit	1.82	ENST00000582229.1	CABYR Ensembl NCBI GeneCards UniProt Show fit	calcium binding tyrosine phosphorylation regulated
chr1_-_27490130 Show fit	1.80	ENST00000618852.5	WASF2 Ensembl NCBI GeneCards UniProt Show fit	WASP family member 2
chr20_+_36154630 Show fit	1.78	ENST00000338074.7 ENST00000636016.2 ENST00000373945.5	EPB41L1 Ensembl NCBI GeneCards UniProt Show fit	erythrocyte membrane protein band 4.1 like 1
chr15_+_73873557 Show fit	1.78	ENST00000300504.7	TBC1D21 Ensembl NCBI GeneCards UniProt Show fit	TBC1 domain family member 21
chr6_-_43629222 Show fit	1.77	ENST00000307126.10	GTPBP2 Ensembl NCBI GeneCards UniProt Show fit	GTP binding protein 2
chr22_+_20507571 Show fit	1.77	ENST00000414658.5 ENST00000432052.5 ENST00000292733.11 ENST00000263205.11 ENST00000406969.5	MED15 Ensembl NCBI GeneCards UniProt Show fit	mediator complex subunit 15
chr18_+_58671439 Show fit	1.76	ENST00000649217.2	MALT1 Ensembl NCBI GeneCards UniProt Show fit	MALT1 paracaspase
chr1_-_150235995 Show fit	1.75	ENST00000436748.6	ANP32E Ensembl NCBI GeneCards UniProt Show fit	acidic nuclear phosphoprotein 32 family member E
chr1_-_154970735 Show fit	1.75	ENST00000368445.9 ENST00000448116.7 ENST00000368449.8	SHC1 Ensembl NCBI GeneCards UniProt Show fit	SHC adaptor protein 1
chr8_-_109975757 Show fit	1.75	ENST00000524391.6	KCNV1 Ensembl NCBI GeneCards UniProt Show fit	potassium voltage-gated channel modifier subfamily V member 1
chr17_-_1486124 Show fit	1.74	ENST00000575158.5	MYO1C Ensembl NCBI GeneCards UniProt Show fit	myosin IC
chr1_+_36156096 Show fit	1.74	ENST00000474796.2 ENST00000373150.8 ENST00000373151.6	MAP7D1 Ensembl NCBI GeneCards UniProt Show fit	MAP7 domain containing 1
chr2_+_169069537 Show fit	1.73	ENST00000428522.5 ENST00000450153.1 ENST00000674881.1 ENST00000421653.5	DHRS9 Ensembl NCBI GeneCards UniProt Show fit	dehydrogenase/reductase 9
chr2_+_89851723 Show fit	1.73	ENST00000429992.2	IGKV2D-40 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 2D-40
chr1_-_150235943 Show fit	1.70	ENST00000533654.5	ANP32E Ensembl NCBI GeneCards UniProt Show fit	acidic nuclear phosphoprotein 32 family member E
chr19_+_926001 Show fit	1.70	ENST00000263620.8	ARID3A Ensembl NCBI GeneCards UniProt Show fit	AT-rich interaction domain 3A
chr4_-_993430 Show fit	1.68	ENST00000361661.6 ENST00000622731.4	SLC26A1 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 26 member 1
chr1_+_156893678 Show fit	1.67	ENST00000292357.8 ENST00000338302.7 ENST00000455314.5	PEAR1 Ensembl NCBI GeneCards UniProt Show fit	platelet endothelial aggregation receptor 1
chr1_+_966466 Show fit	1.66	ENST00000379410.8 ENST00000379407.7 ENST00000379409.6	PLEKHN1 Ensembl NCBI GeneCards UniProt Show fit	pleckstrin homology domain containing N1
chr2_+_89959979 Show fit	1.63	ENST00000453166.2	IGKV2D-28 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 2D-28
chrX_+_49171918 Show fit	1.62	ENST00000376322.7	PLP2 Ensembl NCBI GeneCards UniProt Show fit	proteolipid protein 2
chrX_-_15493234 Show fit	1.62	ENST00000380420.10	PIR Ensembl NCBI GeneCards UniProt Show fit	pirin
chr12_+_56128217 Show fit	1.62	ENST00000267113.4 ENST00000394048.10	ESYT1 Ensembl NCBI GeneCards UniProt Show fit	extended synaptotagmin 1
chr14_-_24337382 Show fit	1.62	ENST00000555591.1 ENST00000554569.1	ENSG00000258973.1 Ensembl NCBI GeneCards UniProt Show fit RIPK3 Ensembl NCBI GeneCards UniProt Show fit	novel transcript receptor interacting serine/threonine kinase 3
chr15_-_25865076 Show fit	1.61	ENST00000619904.1	ATP10A Ensembl NCBI GeneCards UniProt Show fit	ATPase phospholipid transporting 10A (putative)
chr1_+_155033824 Show fit	1.59	ENST00000295542.6 ENST00000423025.6 ENST00000368419.2	DCST1 Ensembl NCBI GeneCards UniProt Show fit	DC-STAMP domain containing 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.6	18.1	GO:0090362	positive regulation of platelet-derived growth factor production(GO:0090362)
3.6	18.1	GO:0072674	multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
2.9	17.4	GO:0007296	vitellogenesis(GO:0007296)
2.8	11.1	GO:1903575	cornified envelope assembly(GO:1903575)
2.1	6.4	GO:0046108	uridine metabolic process(GO:0046108)
2.1	8.6	GO:0002384	hepatic immune response(GO:0002384)
2.0	12.1	GO:0061143	alveolar primary septum development(GO:0061143)
2.0	5.9	GO:0006113	fermentation(GO:0006113) regulation of fermentation(GO:0043465)
1.8	10.6	GO:0061767	negative regulation of lung blood pressure(GO:0061767)
1.4	41.4	GO:0030502	negative regulation of bone mineralization(GO:0030502)
1.3	36.0	GO:0031581	hemidesmosome assembly(GO:0031581)
1.3	8.9	GO:2000660	negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
1.2	3.6	GO:0046521	sphingoid catabolic process(GO:0046521)
1.1	3.4	GO:0070318	positive regulation of G0 to G1 transition(GO:0070318)
1.1	3.3	GO:0014740	negative regulation of muscle hyperplasia(GO:0014740)
1.1	3.3	GO:0038195	urokinase plasminogen activator signaling pathway(GO:0038195)
1.0	3.0	GO:0044007	negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010768) transmission of virus(GO:0019089) dissemination or transmission of symbiont from host(GO:0044007) dissemination or transmission of organism from other organism involved in symbiotic interaction(GO:0051821)
0.9	18.9	GO:0051546	keratinocyte migration(GO:0051546)
0.9	2.8	GO:1903028	positive regulation of opsonization(GO:1903028)
0.9	2.8	GO:1990654	regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
0.9	3.5	GO:0002159	desmosome assembly(GO:0002159)
0.9	2.6	GO:0045645	regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.8	4.2	GO:0071393	cellular response to progesterone stimulus(GO:0071393)
0.8	4.9	GO:0001923	B-1 B cell differentiation(GO:0001923)
0.8	2.4	GO:2000097	regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.8	3.8	GO:1903238	positive regulation of leukocyte tethering or rolling(GO:1903238)
0.7	8.5	GO:1900623	regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.7	1.4	GO:0090271	positive regulation of fibroblast growth factor production(GO:0090271)
0.6	5.3	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
0.6	4.7	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.6	7.5	GO:0035092	sperm chromatin condensation(GO:0035092)
0.6	4.5	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.5	8.7	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.5	1.6	GO:2000452	CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:0035698) regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:2000452)
0.5	2.6	GO:2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.5	1.6	GO:0000117	regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.5	2.0	GO:1905205	positive regulation of connective tissue replacement(GO:1905205)
0.5	6.6	GO:0046541	saliva secretion(GO:0046541)
0.5	2.9	GO:0060356	leucine import(GO:0060356)
0.4	2.7	GO:0035105	sterol regulatory element binding protein import into nucleus(GO:0035105)
0.4	3.5	GO:0032960	regulation of inositol trisphosphate biosynthetic process(GO:0032960) positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.4	6.1	GO:0034242	negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.4	4.3	GO:0071492	cellular response to UV-A(GO:0071492)
0.4	1.7	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
0.4	1.3	GO:0035425	autocrine signaling(GO:0035425)
0.4	1.3	GO:0098759	response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.4	2.9	GO:2000969	positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.4	26.1	GO:0018149	peptide cross-linking(GO:0018149)
0.4	3.2	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.4	1.6	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.4	1.9	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.4	1.1	GO:1902031	regulation of NADP metabolic process(GO:1902031)
0.4	5.5	GO:0060020	Bergmann glial cell differentiation(GO:0060020)
0.4	3.0	GO:2000467	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.4	1.1	GO:0070295	renal water absorption(GO:0070295)
0.4	1.1	GO:1990009	cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473) retinal cell apoptotic process(GO:1990009)
0.4	2.2	GO:0032792	negative regulation of CREB transcription factor activity(GO:0032792)
0.4	1.4	GO:0097325	melanocyte proliferation(GO:0097325)
0.4	0.7	GO:1902304	positive regulation of potassium ion export(GO:1902304)
0.4	1.1	GO:0060720	spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.3	6.3	GO:0002138	retinoic acid biosynthetic process(GO:0002138)
0.3	2.0	GO:0006543	glutamine catabolic process(GO:0006543)
0.3	0.3	GO:0052047	interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.3	1.0	GO:0045556	TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556)
0.3	5.4	GO:2001135	regulation of endocytic recycling(GO:2001135)
0.3	18.7	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.3	7.8	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.3	3.8	GO:0060707	trophoblast giant cell differentiation(GO:0060707)
0.3	0.9	GO:0043988	histone H3-S28 phosphorylation(GO:0043988)
0.3	1.4	GO:0046167	glycerol-3-phosphate biosynthetic process(GO:0046167)
0.3	3.1	GO:2000535	regulation of entry of bacterium into host cell(GO:2000535)
0.3	2.3	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.3	1.7	GO:0006041	glucosamine metabolic process(GO:0006041)
0.3	0.3	GO:0042938	dipeptide transport(GO:0042938)
0.3	0.8	GO:0007518	myoblast fate determination(GO:0007518)
0.3	6.8	GO:0051639	actin filament network formation(GO:0051639)
0.3	2.3	GO:2001206	positive regulation of osteoclast development(GO:2001206)
0.2	8.9	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.2	0.7	GO:1990785	response to water-immersion restraint stress(GO:1990785)
0.2	0.7	GO:2000176	regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.2	0.9	GO:0007206	phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.2	8.4	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.2	1.4	GO:0015680	intracellular copper ion transport(GO:0015680)
0.2	2.9	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.2	2.7	GO:0098734	macromolecule depalmitoylation(GO:0098734)
0.2	1.1	GO:0007406	negative regulation of neuroblast proliferation(GO:0007406)
0.2	1.8	GO:0003172	primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.2	1.7	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.2	1.1	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.2	2.4	GO:2001300	lipoxin metabolic process(GO:2001300)
0.2	1.7	GO:0035879	plasma membrane lactate transport(GO:0035879)
0.2	5.8	GO:0032060	bleb assembly(GO:0032060)
0.2	1.7	GO:0031022	nuclear migration along microfilament(GO:0031022)
0.2	2.0	GO:0050428	purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.2	0.6	GO:0042636	negative regulation of hair cycle(GO:0042636)
0.2	1.4	GO:0060478	acrosomal vesicle exocytosis(GO:0060478)
0.2	2.3	GO:0097283	keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.2	2.3	GO:0030321	transepithelial chloride transport(GO:0030321)
0.2	0.8	GO:0035606	peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.2	0.6	GO:0018874	benzoate metabolic process(GO:0018874)
0.2	2.6	GO:0044351	macropinocytosis(GO:0044351)
0.2	0.7	GO:0002268	follicular dendritic cell differentiation(GO:0002268)
0.2	9.5	GO:0061718	NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.2	9.9	GO:0015701	bicarbonate transport(GO:0015701)
0.2	3.0	GO:0016322	neuron remodeling(GO:0016322)
0.2	0.5	GO:0032455	nerve growth factor processing(GO:0032455)
0.2	0.5	GO:0086097	phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.2	3.1	GO:0071361	cellular response to ethanol(GO:0071361)
0.2	3.6	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.2	1.3	GO:0034141	positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.2	3.4	GO:0070208	protein heterotrimerization(GO:0070208)
0.2	1.6	GO:0001866	NK T cell proliferation(GO:0001866)
0.2	16.7	GO:0070268	cornification(GO:0070268)
0.2	13.2	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.2	2.6	GO:0007021	tubulin complex assembly(GO:0007021)
0.2	1.7	GO:0043654	recognition of apoptotic cell(GO:0043654)
0.2	8.1	GO:0043486	histone exchange(GO:0043486)
0.1	9.2	GO:0035987	endodermal cell differentiation(GO:0035987)
0.1	3.5	GO:0035855	megakaryocyte development(GO:0035855)
0.1	0.9	GO:0045792	negative regulation of cell size(GO:0045792)
0.1	1.0	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.1	1.0	GO:0010482	epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.1	0.4	GO:0098974	postsynaptic actin cytoskeleton organization(GO:0098974)
0.1	1.9	GO:0019388	galactose catabolic process(GO:0019388)
0.1	1.9	GO:0097107	postsynaptic density assembly(GO:0097107) gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.1	13.7	GO:0045669	positive regulation of osteoblast differentiation(GO:0045669)
0.1	0.4	GO:1902938	regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.1	1.2	GO:2000580	regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1	4.0	GO:0045332	phospholipid translocation(GO:0045332)
0.1	2.5	GO:1904778	regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1	0.6	GO:0090131	mesenchyme migration(GO:0090131)
0.1	1.9	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1	0.7	GO:0060750	antral ovarian follicle growth(GO:0001547) mammary gland branching involved in pregnancy(GO:0060745) epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.1	1.5	GO:0071803	positive regulation of podosome assembly(GO:0071803)
0.1	0.8	GO:0060681	branch elongation involved in ureteric bud branching(GO:0060681)
0.1	0.7	GO:0002036	regulation of L-glutamate transport(GO:0002036)
0.1	2.5	GO:0035588	G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.1	2.3	GO:0071985	multivesicular body sorting pathway(GO:0071985)
0.1	1.2	GO:0001765	membrane raft assembly(GO:0001765)
0.1	1.0	GO:1902866	regulation of retina development in camera-type eye(GO:1902866)
0.1	4.6	GO:0009303	termination of RNA polymerase I transcription(GO:0006363) rRNA transcription(GO:0009303)
0.1	0.3	GO:1901656	glucoside transport(GO:0042946) glycoside transport(GO:1901656)
0.1	0.8	GO:0051414	response to cortisol(GO:0051414)
0.1	0.6	GO:1902459	positive regulation of stem cell population maintenance(GO:1902459)
0.1	0.1	GO:0060440	trachea formation(GO:0060440)
0.1	0.8	GO:1901525	negative regulation of macromitophagy(GO:1901525)
0.1	1.3	GO:0015074	DNA integration(GO:0015074)
0.1	1.0	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.1	1.4	GO:0006228	UTP biosynthetic process(GO:0006228)
0.1	0.4	GO:0034224	cellular response to zinc ion starvation(GO:0034224)
0.1	0.6	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.1	0.7	GO:0010624	regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.1	3.1	GO:0071539	protein localization to centrosome(GO:0071539)
0.1	1.3	GO:2000304	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1	1.6	GO:1903543	positive regulation of exosomal secretion(GO:1903543)
0.1	10.3	GO:0030216	keratinocyte differentiation(GO:0030216)
0.1	0.9	GO:0010968	regulation of microtubule nucleation(GO:0010968)
0.1	4.1	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.1	4.8	GO:0030834	regulation of actin filament depolymerization(GO:0030834)
0.1	1.5	GO:0060294	inner dynein arm assembly(GO:0036159) cilium movement involved in cell motility(GO:0060294)
0.1	2.7	GO:0007035	vacuolar acidification(GO:0007035)
0.1	0.4	GO:0006701	progesterone biosynthetic process(GO:0006701) negative regulation of vasoconstriction(GO:0045906)
0.1	0.3	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
0.1	0.9	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.1	1.4	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1	0.4	GO:2001181	positive regulation of interleukin-10 secretion(GO:2001181)
0.1	4.1	GO:0050819	negative regulation of coagulation(GO:0050819)
0.1	0.8	GO:0034625	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1	0.2	GO:0010982	regulation of high-density lipoprotein particle clearance(GO:0010982)
0.1	0.3	GO:0044571	[2Fe-2S] cluster assembly(GO:0044571)
0.1	0.5	GO:0030421	defecation(GO:0030421)
0.1	1.1	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.1	1.5	GO:0042481	regulation of odontogenesis(GO:0042481)
0.1	0.7	GO:0070307	lens fiber cell development(GO:0070307)
0.1	0.8	GO:0019344	cysteine biosynthetic process(GO:0019344)
0.1	3.6	GO:0030574	collagen catabolic process(GO:0030574)
0.1	0.8	GO:0036155	acylglycerol acyl-chain remodeling(GO:0036155)
0.1	0.5	GO:0060742	epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.1	1.2	GO:0016024	CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1	0.2	GO:0002188	translation reinitiation(GO:0002188)
0.1	1.7	GO:0032465	regulation of cytokinesis(GO:0032465)
0.1	1.1	GO:0050962	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1	0.8	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.1	0.2	GO:0044210	'de novo' CTP biosynthetic process(GO:0044210)
0.0	1.0	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	5.6	GO:0002062	chondrocyte differentiation(GO:0002062)
0.0	1.7	GO:0007176	regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.0	0.6	GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0	0.3	GO:1902715	positive regulation of interferon-gamma secretion(GO:1902715)
0.0	0.7	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0	0.6	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.0	0.3	GO:0030728	ovulation(GO:0030728)
0.0	1.0	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	3.2	GO:0006968	cellular defense response(GO:0006968)
0.0	0.1	GO:1901052	sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.0	2.7	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0	0.8	GO:0051683	establishment of Golgi localization(GO:0051683)
0.0	2.1	GO:1901385	regulation of voltage-gated calcium channel activity(GO:1901385)
0.0	2.4	GO:0042058	regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.0	0.2	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.0	0.3	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
0.0	0.2	GO:0015862	uridine transport(GO:0015862)
0.0	0.1	GO:0060842	arterial endothelial cell differentiation(GO:0060842)
0.0	0.8	GO:0006700	C21-steroid hormone biosynthetic process(GO:0006700)
0.0	0.8	GO:0051412	response to corticosterone(GO:0051412)
0.0	1.8	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.0	1.2	GO:1904659	hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0	2.1	GO:0006334	nucleosome assembly(GO:0006334)
0.0	1.8	GO:0003281	ventricular septum development(GO:0003281)
0.0	0.2	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.0	2.3	GO:0048208	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0	0.3	GO:0030091	protein repair(GO:0030091)
0.0	1.1	GO:0009250	glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0	0.1	GO:0072365	regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.0	0.1	GO:0035552	oxidative single-stranded DNA demethylation(GO:0035552)
0.0	4.3	GO:0002377	immunoglobulin production(GO:0002377)
0.0	2.0	GO:0043462	regulation of ATPase activity(GO:0043462)
0.0	0.4	GO:0045604	regulation of epidermal cell differentiation(GO:0045604)
0.0	1.6	GO:0030224	monocyte differentiation(GO:0030224)
0.0	0.2	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0	0.5	GO:0048240	sperm capacitation(GO:0048240)
0.0	0.4	GO:2000010	positive regulation of protein localization to cell surface(GO:2000010)
0.0	0.1	GO:0006617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0	0.2	GO:0014718	positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0	0.3	GO:0034498	early endosome to Golgi transport(GO:0034498)
0.0	0.2	GO:0051014	actin filament severing(GO:0051014)
0.0	0.3	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	2.7	GO:0030038	contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0	0.2	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.9	GO:0003231	cardiac ventricle development(GO:0003231)
0.0	0.1	GO:0036149	phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0	0.2	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.2	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.0	0.3	GO:0034134	toll-like receptor 2 signaling pathway(GO:0034134)
0.0	0.3	GO:0030214	hyaluronan catabolic process(GO:0030214)
0.0	0.8	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.2	GO:0005980	glycogen catabolic process(GO:0005980)
0.0	0.4	GO:0030207	chondroitin sulfate catabolic process(GO:0030207)
0.0	0.3	GO:0034374	low-density lipoprotein particle remodeling(GO:0034374)
0.0	1.4	GO:0001578	microtubule bundle formation(GO:0001578)
0.0	0.4	GO:0036150	phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0	0.0	GO:0044778	meiotic DNA integrity checkpoint(GO:0044778)
0.0	0.0	GO:0033603	positive regulation of dopamine secretion(GO:0033603)
0.0	0.5	GO:0031103	axon regeneration(GO:0031103)
0.0	1.8	GO:0098869	cellular oxidant detoxification(GO:0098869)
0.0	0.7	GO:0045670	regulation of osteoclast differentiation(GO:0045670)
0.0	0.6	GO:0034198	cellular response to amino acid starvation(GO:0034198)
0.0	0.2	GO:0097240	meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0	1.2	GO:0006096	glycolytic process(GO:0006096)
0.0	0.7	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.2	GO:0035729	cellular response to hepatocyte growth factor stimulus(GO:0035729)
0.0	2.0	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0	0.1	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0	0.0	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0	0.0	GO:1905232	cellular response to L-glutamate(GO:1905232)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.4	24.0	GO:0005610	laminin-5 complex(GO:0005610)
2.1	41.7	GO:0031089	platelet dense granule lumen(GO:0031089)
1.8	3.6	GO:0043259	laminin-10 complex(GO:0043259)
1.7	8.6	GO:0005896	interleukin-6 receptor complex(GO:0005896)
1.6	4.7	GO:0043256	laminin complex(GO:0043256)
1.2	10.6	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
1.1	6.6	GO:0030934	anchoring collagen complex(GO:0030934)
1.0	4.9	GO:0032449	CBM complex(GO:0032449)
0.8	8.5	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.8	2.3	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.7	43.3	GO:0001533	cornified envelope(GO:0001533)
0.7	8.7	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.7	2.2	GO:1990622	CHOP-ATF3 complex(GO:1990622)
0.7	6.8	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.6	3.2	GO:0045160	myosin I complex(GO:0045160)
0.5	1.6	GO:0033565	ESCRT-0 complex(GO:0033565)
0.5	19.5	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.5	1.8	GO:0097229	sperm end piece(GO:0097229)
0.4	1.7	GO:0070435	Shc-EGFR complex(GO:0070435)
0.4	8.1	GO:0000812	Swr1 complex(GO:0000812)
0.4	3.1	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.4	1.5	GO:0036156	inner dynein arm(GO:0036156)
0.3	2.7	GO:0005827	polar microtubule(GO:0005827)
0.3	4.7	GO:0071438	invadopodium membrane(GO:0071438)
0.3	1.9	GO:0097149	centralspindlin complex(GO:0097149)
0.3	0.9	GO:0071148	TEAD-1-YAP complex(GO:0071148)
0.2	5.7	GO:0030056	hemidesmosome(GO:0030056)
0.2	2.7	GO:0005638	lamin filament(GO:0005638)
0.2	1.4	GO:0002081	inner acrosomal membrane(GO:0002079) outer acrosomal membrane(GO:0002081)
0.2	2.6	GO:0097512	cardiac myofibril(GO:0097512)
0.2	3.7	GO:0008091	spectrin(GO:0008091)
0.2	0.6	GO:0034515	proteasome storage granule(GO:0034515)
0.2	9.9	GO:0043034	costamere(GO:0043034)
0.2	0.6	GO:0019031	viral envelope(GO:0019031) viral membrane(GO:0036338)
0.2	3.1	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.2	0.7	GO:0033257	Bcl3/NF-kappaB2 complex(GO:0033257)
0.2	5.4	GO:0005865	striated muscle thin filament(GO:0005865)
0.2	17.8	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.2	4.7	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.2	1.1	GO:0035686	sperm fibrous sheath(GO:0035686)
0.2	3.7	GO:0097342	ripoptosome(GO:0097342)
0.2	1.8	GO:0005955	calcineurin complex(GO:0005955)
0.2	2.7	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.2	3.0	GO:0042589	zymogen granule membrane(GO:0042589)
0.2	3.4	GO:0042641	actomyosin(GO:0042641)
0.1	2.2	GO:0030478	actin cap(GO:0030478)
0.1	0.1	GO:0002139	stereocilia coupling link(GO:0002139)
0.1	22.5	GO:0005882	intermediate filament(GO:0005882)
0.1	0.9	GO:0030057	desmosome(GO:0030057)
0.1	17.6	GO:0042734	presynaptic membrane(GO:0042734)
0.1	1.8	GO:0031209	SCAR complex(GO:0031209)
0.1	17.7	GO:0031985	Golgi cisterna(GO:0031985)
0.1	0.8	GO:0070436	Grb2-EGFR complex(GO:0070436)
0.1	1.9	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.1	0.5	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.1	1.5	GO:0008290	F-actin capping protein complex(GO:0008290)
0.1	13.9	GO:0005604	basement membrane(GO:0005604)
0.1	4.4	GO:0002102	podosome(GO:0002102)
0.1	1.7	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	2.6	GO:0005719	nuclear euchromatin(GO:0005719)
0.1	1.2	GO:0019774	proteasome core complex, beta-subunit complex(GO:0019774)
0.1	0.6	GO:0098559	cytoplasmic side of early endosome membrane(GO:0098559)
0.1	2.3	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.1	0.3	GO:0044279	other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.1	0.8	GO:0097452	GAIT complex(GO:0097452)
0.1	0.7	GO:0097550	transcriptional preinitiation complex(GO:0097550)
0.1	2.7	GO:0031528	microvillus membrane(GO:0031528)
0.1	2.4	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.1	0.3	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.1	1.2	GO:0005641	nuclear envelope lumen(GO:0005641)
0.1	5.9	GO:1904724	tertiary granule lumen(GO:1904724)
0.1	1.7	GO:0001891	phagocytic cup(GO:0001891)
0.1	2.0	GO:0044232	organelle membrane contact site(GO:0044232)
0.1	0.6	GO:0032585	multivesicular body membrane(GO:0032585)
0.1	0.9	GO:0031931	TORC1 complex(GO:0031931)
0.1	0.4	GO:0005854	nascent polypeptide-associated complex(GO:0005854)
0.1	0.4	GO:0035748	myelin sheath abaxonal region(GO:0035748)
0.1	7.3	GO:0005901	caveola(GO:0005901)
0.1	18.0	GO:0031012	extracellular matrix(GO:0031012)
0.1	1.5	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.1	14.5	GO:0030027	lamellipodium(GO:0030027)
0.1	0.3	GO:0033553	rDNA heterochromatin(GO:0033553)
0.1	0.2	GO:0055028	cortical microtubule(GO:0055028)
0.0	1.3	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.6	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	19.3	GO:0030667	secretory granule membrane(GO:0030667)
0.0	1.2	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	2.6	GO:0055038	recycling endosome membrane(GO:0055038)
0.0	0.6	GO:0061700	GATOR2 complex(GO:0061700)
0.0	0.4	GO:0070652	HAUS complex(GO:0070652)
0.0	1.8	GO:0016592	mediator complex(GO:0016592)
0.0	0.4	GO:0031597	cytosolic proteasome complex(GO:0031597)
0.0	0.2	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.0	0.6	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.0	0.3	GO:0016272	prefoldin complex(GO:0016272)
0.0	2.4	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.8	GO:0005922	connexon complex(GO:0005922)
0.0	0.9	GO:0014704	intercalated disc(GO:0014704)
0.0	0.7	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	48.9	GO:0005615	extracellular space(GO:0005615)
0.0	10.0	GO:0030055	cell-substrate junction(GO:0030055)
0.0	0.2	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	1.0	GO:0030315	T-tubule(GO:0030315)
0.0	1.3	GO:0031526	brush border membrane(GO:0031526)
0.0	1.0	GO:0005903	brush border(GO:0005903)
0.0	2.5	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.0	1.4	GO:0042383	sarcolemma(GO:0042383)
0.0	0.5	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.3	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.3	GO:0031229	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0	1.1	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.5	GO:0030686	90S preribosome(GO:0030686)
0.0	0.4	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
0.0	1.1	GO:0042470	melanosome(GO:0042470) pigment granule(GO:0048770)
0.0	0.2	GO:0005845	mRNA cap binding complex(GO:0005845)
0.0	0.5	GO:0005902	microvillus(GO:0005902)
0.0	2.0	GO:0005938	cell cortex(GO:0005938)
0.0	0.6	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.0	1.6	GO:0016363	nuclear matrix(GO:0016363)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.9	41.5	GO:0005134	interleukin-2 receptor binding(GO:0005134)
3.9	11.7	GO:0005150	interleukin-1, Type I receptor binding(GO:0005150)
2.9	8.8	GO:0070119	ciliary neurotrophic factor binding(GO:0070119)
2.1	6.4	GO:0004850	uridine phosphorylase activity(GO:0004850)
1.8	10.6	GO:0031962	mineralocorticoid receptor binding(GO:0031962)
1.2	4.7	GO:0050119	N-acetylglucosamine deacetylase activity(GO:0050119)
1.1	4.6	GO:0042134	rRNA primary transcript binding(GO:0042134)
1.1	6.8	GO:1990254	keratin filament binding(GO:1990254)
1.1	7.8	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.8	3.2	GO:0004992	platelet activating factor receptor activity(GO:0004992)
0.7	8.7	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.7	9.4	GO:0030280	structural constituent of epidermis(GO:0030280)
0.7	6.8	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.6	6.2	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.6	4.8	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.6	1.7	GO:0008859	exoribonuclease II activity(GO:0008859)
0.5	21.3	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.5	2.6	GO:0001010	transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.5	3.6	GO:0017050	sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.5	2.4	GO:0016404	15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.5	1.9	GO:0003978	UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.4	4.2	GO:0071253	connexin binding(GO:0071253)
0.4	1.3	GO:0019959	interleukin-8 binding(GO:0019959)
0.4	3.0	GO:0050815	phosphoserine binding(GO:0050815) phosphothreonine binding(GO:0050816)
0.4	2.3	GO:0045029	UDP-activated nucleotide receptor activity(GO:0045029)
0.4	1.1	GO:0004618	phosphoglycerate kinase activity(GO:0004618)
0.4	1.4	GO:0016532	superoxide dismutase copper chaperone activity(GO:0016532)
0.3	1.4	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.3	2.0	GO:0004359	glutaminase activity(GO:0004359)
0.3	2.1	GO:0048408	epidermal growth factor binding(GO:0048408)
0.3	8.1	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.3	0.9	GO:0004711	ribosomal protein S6 kinase activity(GO:0004711)
0.3	1.4	GO:0004370	glycerol kinase activity(GO:0004370)
0.3	0.8	GO:0050613	delta14-sterol reductase activity(GO:0050613)
0.3	5.7	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.3	1.3	GO:0016230	sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.3	2.7	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.3	4.5	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.3	0.8	GO:0035605	peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.3	3.8	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.2	0.7	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.2	1.0	GO:0008426	protein kinase C inhibitor activity(GO:0008426)
0.2	2.7	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.2	2.8	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.2	9.1	GO:0005540	hyaluronic acid binding(GO:0005540)
0.2	2.0	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2	2.9	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.2	1.1	GO:0004473	malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.2	2.7	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2	4.2	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.2	2.4	GO:0042731	PH domain binding(GO:0042731)
0.2	0.8	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.2	0.4	GO:0005135	interleukin-3 receptor binding(GO:0005135)
0.2	3.6	GO:0005132	type I interferon receptor binding(GO:0005132)
0.2	2.1	GO:0004969	histamine receptor activity(GO:0004969)
0.2	1.2	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.2	5.8	GO:0017160	Ral GTPase binding(GO:0017160)
0.2	1.2	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.2	9.5	GO:0051183	vitamin transporter activity(GO:0051183)
0.2	25.9	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.2	0.9	GO:0043208	glycosphingolipid binding(GO:0043208)
0.2	2.6	GO:0055106	ubiquitin-protein transferase regulator activity(GO:0055106)
0.2	3.1	GO:0004383	guanylate cyclase activity(GO:0004383)
0.2	1.0	GO:0042835	BRE binding(GO:0042835)
0.2	3.6	GO:0051400	BH domain binding(GO:0051400)
0.2	2.0	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.2	16.1	GO:0097110	scaffold protein binding(GO:0097110)
0.2	0.5	GO:0001596	angiotensin type I receptor activity(GO:0001596)
0.2	2.9	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.2	50.8	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.2	3.4	GO:0016918	retinal binding(GO:0016918)
0.1	1.7	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.1	1.3	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.1	0.4	GO:0098918	structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.1	0.3	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
0.1	2.2	GO:0043522	leucine zipper domain binding(GO:0043522)
0.1	4.0	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.1	0.4	GO:1903135	cupric ion binding(GO:1903135)
0.1	1.2	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.1	3.8	GO:0015035	protein disulfide oxidoreductase activity(GO:0015035)
0.1	0.5	GO:0005163	nerve growth factor receptor binding(GO:0005163)
0.1	0.7	GO:0038052	RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1	0.8	GO:0030284	estrogen receptor activity(GO:0030284)
0.1	0.7	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.1	1.2	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.1	3.2	GO:0031489	myosin V binding(GO:0031489)
0.1	1.4	GO:0019215	intermediate filament binding(GO:0019215)
0.1	2.3	GO:0045294	alpha-catenin binding(GO:0045294)
0.1	2.3	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1	2.3	GO:0097109	neuroligin family protein binding(GO:0097109)
0.1	14.0	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.1	1.5	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1	5.2	GO:0016667	oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
0.1	0.4	GO:0004991	parathyroid hormone receptor activity(GO:0004991)
0.1	1.0	GO:0015321	sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.1	2.6	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1	0.3	GO:0042947	glucoside transmembrane transporter activity(GO:0042947)
0.1	1.0	GO:0048406	nerve growth factor binding(GO:0048406)
0.1	3.7	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.1	3.5	GO:0019956	chemokine binding(GO:0019956)
0.1	1.6	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1	2.7	GO:0045503	dynein light chain binding(GO:0045503)
0.1	1.8	GO:0003680	AT DNA binding(GO:0003680)
0.1	3.1	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.1	2.6	GO:0005523	tropomyosin binding(GO:0005523)
0.1	0.3	GO:0051431	corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.1	5.3	GO:0005080	protein kinase C binding(GO:0005080)
0.1	2.5	GO:0005212	structural constituent of eye lens(GO:0005212)
0.1	13.1	GO:0005178	integrin binding(GO:0005178)
0.1	2.4	GO:0022848	acetylcholine-gated cation channel activity(GO:0022848)
0.1	0.8	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.1	3.0	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.1	5.3	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1	2.3	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1	0.8	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
0.1	1.7	GO:0043495	protein anchor(GO:0043495)
0.1	0.8	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1	0.8	GO:0009922	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1	0.6	GO:0050544	arachidonic acid binding(GO:0050544)
0.1	2.8	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.1	1.2	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.1	1.7	GO:0008200	ion channel inhibitor activity(GO:0008200) channel inhibitor activity(GO:0016248)
0.1	1.3	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1	0.3	GO:0023024	MHC class I protein complex binding(GO:0023024)
0.1	0.3	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1	0.3	GO:1990460	leptin receptor binding(GO:1990460)
0.1	4.9	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.1	0.6	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.1	0.9	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
0.1	0.4	GO:0061133	endopeptidase activator activity(GO:0061133)
0.1	0.3	GO:0003875	ADP-ribosylarginine hydrolase activity(GO:0003875)
0.1	0.4	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
0.1	10.5	GO:0044325	ion channel binding(GO:0044325)
0.1	0.5	GO:0004565	beta-galactosidase activity(GO:0004565)
0.1	0.2	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.1	0.2	GO:0003883	CTP synthase activity(GO:0003883)
0.0	0.6	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	44.8	GO:0005198	structural molecule activity(GO:0005198)
0.0	2.8	GO:0043531	ADP binding(GO:0043531)
0.0	1.8	GO:0051393	alpha-actinin binding(GO:0051393)
0.0	3.7	GO:0043621	protein self-association(GO:0043621)
0.0	0.8	GO:0036374	glutathione hydrolase activity(GO:0036374)
0.0	0.2	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.7	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.0	0.1	GO:0008480	sarcosine dehydrogenase activity(GO:0008480)
0.0	0.9	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.8	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.1	GO:0070984	SET domain binding(GO:0070984)
0.0	0.3	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	1.1	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.6	GO:0048156	tau protein binding(GO:0048156)
0.0	0.7	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	4.8	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.2	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.0	0.4	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.0	0.7	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.0	4.3	GO:0008201	heparin binding(GO:0008201)
0.0	0.1	GO:0035514	DNA demethylase activity(GO:0035514)
0.0	9.3	GO:0003924	GTPase activity(GO:0003924)
0.0	0.9	GO:0004622	lysophospholipase activity(GO:0004622)
0.0	0.1	GO:0005436	sodium:phosphate symporter activity(GO:0005436)
0.0	1.1	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.5	GO:0047617	acyl-CoA hydrolase activity(GO:0047617)
0.0	0.6	GO:0004707	MAP kinase activity(GO:0004707)
0.0	5.0	GO:0000287	magnesium ion binding(GO:0000287)
0.0	0.2	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.1	GO:0070095	fructose-6-phosphate binding(GO:0070095)
0.0	0.1	GO:0031728	CCR3 chemokine receptor binding(GO:0031728)
0.0	2.2	GO:0002039	p53 binding(GO:0002039)
0.0	0.3	GO:0001013	RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0	0.2	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.5	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.0	0.3	GO:0097602	cullin family protein binding(GO:0097602)
0.0	0.6	GO:0017022	myosin binding(GO:0017022)
0.0	0.1	GO:0031708	endothelin B receptor binding(GO:0031708)
0.0	0.1	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.0	0.3	GO:0046965	retinoid X receptor binding(GO:0046965)
0.0	2.0	GO:0004984	olfactory receptor activity(GO:0004984)
0.0	0.7	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	0.8	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	6.6	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0	0.5	GO:0050699	WW domain binding(GO:0050699)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	1.0	GO:0005525	GTP binding(GO:0005525)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.9	37.0	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.7	12.8	ST STAT3 PATHWAY	STAT3 Pathway
0.5	31.9	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.3	9.5	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.3	10.6	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2	18.2	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.2	7.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.2	9.6	PID IL1 PATHWAY	IL1-mediated signaling events
0.2	14.6	PID RHOA PATHWAY	RhoA signaling pathway
0.2	53.1	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.2	8.9	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.2	10.7	PID BCR 5PATHWAY	BCR signaling pathway
0.2	3.1	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.2	3.2	ST G ALPHA S PATHWAY	G alpha s Pathway
0.1	4.3	PID S1P S1P1 PATHWAY	S1P1 pathway
0.1	40.6	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1	5.3	PID RAS PATHWAY	Regulation of Ras family activation
0.1	6.6	NABA COLLAGENS	Genes encoding collagen proteins
0.1	0.6	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.1	4.8	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.1	8.0	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.1	2.1	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1	2.9	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.1	2.1	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.1	3.7	PID AURORA B PATHWAY	Aurora B signaling
0.1	3.5	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.1	0.6	PID NECTIN PATHWAY	Nectin adhesion pathway
0.1	3.0	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.1	3.0	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	2.5	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	1.8	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	0.9	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	0.5	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.7	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	16.5	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.0	2.2	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.5	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.5	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.0	0.7	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	2.3	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	1.3	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.0	1.9	PID PLK1 PATHWAY	PLK1 signaling events
0.0	0.6	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	0.9	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	0.5	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.8	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.5	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.6	PID CONE PATHWAY	Visual signal transduction: Cones
0.0	2.1	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.0	0.3	PID FGF PATHWAY	FGF signaling pathway
0.0	0.3	PID IL12 2PATHWAY	IL12-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	16.9	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.5	8.6	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.4	9.9	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.4	7.8	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.4	6.4	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.3	11.2	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.2	4.2	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.2	0.5	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.2	4.2	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.2	9.7	REACTOME AMYLOIDS	Genes involved in Amyloids
0.2	3.1	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.2	4.5	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2	29.3	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.2	11.6	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.2	3.0	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2	10.4	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.2	3.6	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.2	2.2	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1	1.0	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.1	2.6	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.1	2.6	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1	2.9	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.1	4.7	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.1	2.3	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.1	2.4	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1	1.2	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.1	2.8	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.1	4.6	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.1	5.2	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	2.6	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	3.9	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1	2.7	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.1	1.1	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1	3.3	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1	3.9	REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING	Genes involved in Integrin alphaIIb beta3 signaling
0.1	6.6	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	2.4	REACTOME EXTRACELLULAR MATRIX ORGANIZATION	Genes involved in Extracellular matrix organization
0.1	4.4	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.1	2.0	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.1	1.3	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.1	3.4	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.1	0.7	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1	1.9	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1	1.3	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	1.8	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.6	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	1.7	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	6.9	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	2.0	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	3.5	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.8	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.5	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.8	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	1.7	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	9.0	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	1.8	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.0	0.5	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.8	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	1.4	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.8	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.5	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	0.6	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	1.7	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.8	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	2.6	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	0.8	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	1.3	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.8	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	2.9	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	1.9	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.5	REACTOME LIPOPROTEIN METABOLISM	Genes involved in Lipoprotein metabolism
0.0	1.0	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	2.0	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.0	0.7	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.0	0.6	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	1.2	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.4	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.2	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0	0.2	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors

Results for FOSL2_SMARCC1

Z-value: 2.04

Motif logo

Transcription factors associated with FOSL2_SMARCC1

Activity-expression correlation:

Activity profile of FOSL2_SMARCC1 motif

Sorted Z-values of FOSL2_SMARCC1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FOSL2_SMARCC1

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: