Project
Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)
Navigation
Downloads
Results for FOXA1
Z-value: 0.83
Motif logo
Transcription factors associated with FOXA1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| FOXA1 | hg38_v1_chr14_-_37595224_37595281 | 0.15 | 4.4e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of FOXA1
| Promoter | Score | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr20_+_33235987 Show fit | 4.67 |
ENST00000375422.6
ENST00000375413.8 ENST00000354297.9 |
BPI fold containing family A member 1 |
|
| chr4_+_164754045 Show fit | 4.24 |
ENST00000515485.5
|
small integral membrane protein 31 |
|
| chr4_+_164754116 Show fit | 3.32 |
ENST00000507311.1
|
small integral membrane protein 31 |
|
| chr10_-_46046264 Show fit | 2.39 |
ENST00000581478.5
ENST00000582163.3 |
microseminoprotein beta |
|
| chr12_-_71157992 Show fit | 1.76 |
ENST00000247829.8
|
tetraspanin 8 |
|
| chr12_-_71157872 Show fit | 1.73 |
ENST00000546561.2
|
tetraspanin 8 |
|
| chr2_+_70935919 Show fit | 1.65 |
ENST00000412314.5
|
ATPase H+ transporting V1 subunit B1 |
|
| chr2_+_70935864 Show fit | 1.65 |
ENST00000234396.10
ENST00000454446.6 |
ATPase H+ transporting V1 subunit B1 |
|
| chr9_-_86947496 Show fit | 1.56 |
ENST00000298743.9
|
growth arrest specific 1 |
|
| chr7_+_80602150 Show fit | 1.54 |
ENST00000309881.11
|
CD36 molecule |
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 4.7 | GO:1900191 | biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229) |
| 0.1 | 3.3 | GO:0015991 | ATP hydrolysis coupled proton transport(GO:0015991) |
| 0.0 | 3.2 | GO:1900047 | negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047) |
| 0.3 | 3.1 | GO:0072564 | response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334) |
| 0.0 | 2.0 | GO:0006968 | cellular defense response(GO:0006968) |
| 0.3 | 1.9 | GO:0003051 | angiotensin catabolic process in blood(GO:0002005) angiotensin-mediated drinking behavior(GO:0003051) |
| 0.1 | 1.9 | GO:0072189 | ureter development(GO:0072189) |
| 0.2 | 1.8 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
| 0.4 | 1.6 | GO:0072134 | nephrogenic mesenchyme morphogenesis(GO:0072134) allantois development(GO:1905069) |
| 0.1 | 1.6 | GO:0060628 | regulation of ER to Golgi vesicle-mediated transport(GO:0060628) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 3.3 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
| 0.1 | 2.1 | GO:0042589 | zymogen granule membrane(GO:0042589) |
| 0.0 | 1.9 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.0 | 1.6 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.0 | 1.2 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.1 | 0.7 | GO:0098647 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 0.2 | 0.6 | GO:0016938 | kinesin I complex(GO:0016938) |
| 0.1 | 0.6 | GO:0032302 | MutSalpha complex(GO:0032301) MutSbeta complex(GO:0032302) |
| 0.0 | 0.6 | GO:0032590 | dendrite membrane(GO:0032590) |
| 0.2 | 0.5 | GO:0033150 | cytoskeletal calyx(GO:0033150) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.3 | GO:0015078 | hydrogen ion transmembrane transporter activity(GO:0015078) |
| 0.4 | 3.1 | GO:0070892 | lipoteichoic acid receptor activity(GO:0070892) |
| 0.0 | 2.6 | GO:0005178 | integrin binding(GO:0005178) |
| 0.4 | 1.9 | GO:0008241 | peptidyl-dipeptidase activity(GO:0008241) |
| 0.6 | 1.7 | GO:0035375 | zymogen binding(GO:0035375) |
| 0.1 | 1.6 | GO:0070700 | BMP receptor binding(GO:0070700) |
| 0.0 | 1.6 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.0 | 1.4 | GO:0070410 | co-SMAD binding(GO:0070410) |
| 0.2 | 1.2 | GO:0003835 | beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835) |
| 0.1 | 1.2 | GO:0016015 | morphogen activity(GO:0016015) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.0 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 1.7 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.0 | 1.7 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.1 | 1.6 | PID ALK2 PATHWAY | ALK2 signaling events |
| 0.0 | 1.6 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 1.2 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.0 | 0.8 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.0 | 0.3 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.0 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.1 | 3.3 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |
| 0.0 | 1.4 | REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 0.1 | 1.2 | REACTOME N GLYCAN ANTENNAE ELONGATION | Genes involved in N-Glycan antennae elongation |
| 0.0 | 1.2 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.0 | 0.8 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.0 | 0.7 | REACTOME IRON UPTAKE AND TRANSPORT | Genes involved in Iron uptake and transport |
| 0.0 | 0.7 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.0 | 0.7 | REACTOME GLUCOSE TRANSPORT | Genes involved in Glucose transport |
| 0.0 | 0.6 | REACTOME KINESINS | Genes involved in Kinesins |