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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for FOXA2_FOXJ3

Z-value: 0.74

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Transcription factors associated with FOXA2_FOXJ3

Gene Symbol Gene ID Gene Info
FOXA2
ENSG00000125798.15 FOXA2
FOXJ3
ENSG00000198815.9 FOXJ3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXA2hg38_v1_chr20_-_22584547_22584585,
hg38_v1_chr20_-_22585451_22585459		-0.251.9e-01Click!
FOXJ3hg38_v1_chr1_-_42335869_42335891,
hg38_v1_chr1_-_42335189_42335242		0.057.9e-01Click!

Activity profile of FOXA2_FOXJ3 motif

Sorted Z-values of FOXA2_FOXJ3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXA2_FOXJ3

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr13_-_38990856 4.54 ENST00000423210.1
STOML3
stomatin like 3
chr13_-_38990824 3.23 ENST00000379631.9
STOML3
stomatin like 3
chr5_-_110726649 2.78 ENST00000511883.6
ENST00000455884.7
TMEM232
transmembrane protein 232
chr11_-_114595750 2.34 ENST00000424261.6
NXPE4
neurexophilin and PC-esterase domain family member 4
chr11_-_114595777 2.25 ENST00000375478.4
NXPE4
neurexophilin and PC-esterase domain family member 4
chr2_+_232662733 2.03 ENST00000410095.5
ENST00000611312.1
EFHD1
EF-hand domain family member D1
chr13_-_61415508 1.90 ENST00000409204.4
PCDH20
protocadherin 20
chr12_-_68302872 1.78 ENST00000539972.5
MDM1
Mdm1 nuclear protein
chr4_+_164754045 1.73 ENST00000515485.5
SMIM31
small integral membrane protein 31
chr4_+_69995958 1.69 ENST00000381060.2
ENST00000246895.9
STATH
statherin
chr12_+_48904116 1.43 ENST00000552942.5
ENST00000320516.5
CCDC65
coiled-coil domain containing 65
chr9_-_4300049 1.41 ENST00000381971.8
GLIS3
GLIS family zinc finger 3
chr6_+_52420992 1.38 ENST00000636954.1
ENST00000636566.1
ENST00000638075.1
EFHC1
EF-hand domain containing 1
chr1_+_226940279 1.37 ENST00000366778.5
ENST00000366777.4
COQ8A
coenzyme Q8A
chr4_+_164754116 1.35 ENST00000507311.1
SMIM31
small integral membrane protein 31
chrX_-_66040057 1.19 ENST00000412866.2
VSIG4
V-set and immunoglobulin domain containing 4
chr17_-_41047267 1.19 ENST00000542137.1
ENST00000391419.3
KRTAP2-1
keratin associated protein 2-1
chrX_-_66040072 1.18 ENST00000374737.9
VSIG4
V-set and immunoglobulin domain containing 4
chrX_-_66040107 1.16 ENST00000455586.6
VSIG4
V-set and immunoglobulin domain containing 4
chr17_-_31858927 1.11 ENST00000579741.1
COPRS
coordinator of PRMT5 and differentiation stimulator
chr10_+_96000091 1.01 ENST00000424464.5
ENST00000410012.6
ENST00000344386.3
CC2D2B
coiled-coil and C2 domain containing 2B
chr16_-_53052849 1.00 ENST00000619363.2
ENSG00000277639.2
novel protein
chrY_+_14522573 1.00 ENST00000643089.1
ENST00000382872.5
NLGN4Y
neuroligin 4 Y-linked
chr18_-_27185284 0.99 ENST00000580774.2
ENST00000618847.5
CHST9
carbohydrate sulfotransferase 9
chr9_+_27109393 0.96 ENST00000406359.8
TEK
TEK receptor tyrosine kinase
chr8_+_36784324 0.92 ENST00000523973.5
ENST00000399881.8
KCNU1
potassium calcium-activated channel subfamily U member 1
chr9_+_122159886 0.90 ENST00000373764.8
ENST00000536616.5
MORN5
MORN repeat containing 5
chr1_-_206921987 0.85 ENST00000530505.1
ENST00000442471.4
FCMR
Fc fragment of IgM receptor
chr6_-_29045175 0.82 ENST00000377175.2
OR2W1
olfactory receptor family 2 subfamily W member 1
chr17_-_31858952 0.82 ENST00000378634.6
COPRS
coordinator of PRMT5 and differentiation stimulator
chr12_-_51324652 0.81 ENST00000544402.5
BIN2
bridging integrator 2
chr9_+_72114595 0.80 ENST00000545168.5
GDA
guanine deaminase
chr1_-_216805367 0.78 ENST00000360012.7
ESRRG
estrogen related receptor gamma
chr12_+_48904105 0.76 ENST00000266984.9
CCDC65
coiled-coil domain containing 65
chr12_-_12684490 0.74 ENST00000540510.1
GPR19
G protein-coupled receptor 19
chr16_+_56191476 0.74 ENST00000262493.12
GNAO1
G protein subunit alpha o1
chr12_-_121669646 0.73 ENST00000355329.7
MORN3
MORN repeat containing 3
chr4_-_137532452 0.69 ENST00000412923.6
ENST00000511115.5
ENST00000344876.9
ENST00000507846.5
ENST00000510305.5
ENST00000611581.1
PCDH18
protocadherin 18
chr6_-_87095059 0.66 ENST00000369582.6
ENST00000610310.3
ENST00000630630.2
ENST00000627148.3
ENST00000625577.1
CGA
glycoprotein hormones, alpha polypeptide
chr1_-_160523204 0.65 ENST00000368055.1
ENST00000368057.8
ENST00000368059.7
SLAMF6
SLAM family member 6
chr4_-_69653223 0.64 ENST00000286604.8
ENST00000505512.1
ENST00000514019.1
UGT2A1
UDP glucuronosyltransferase family 2 member A1 complex locus
chr1_-_20119527 0.64 ENST00000375105.8
ENST00000617227.1
PLA2G2D
phospholipase A2 group IID
chr3_-_108222362 0.63 ENST00000492106.1
IFT57
intraflagellar transport 57
chr1_-_151372683 0.63 ENST00000458566.5
ENST00000447402.7
ENST00000426705.6
ENST00000368868.10
SELENBP1
selenium binding protein 1
chr1_-_206921867 0.62 ENST00000628511.2
ENST00000367091.8
FCMR
Fc fragment of IgM receptor
chr11_+_72080313 0.61 ENST00000307198.11
ENST00000538413.6
ENST00000642648.1
ENST00000289488.7
ENSG00000284922.2
LRTOMT
leucine rich transmembrane and O-methyltransferase domain containing
leucine rich transmembrane and O-methyltransferase domain containing
chr3_+_132597260 0.60 ENST00000249887.3
ACKR4
atypical chemokine receptor 4
chr1_+_3690654 0.59 ENST00000378285.5
ENST00000378280.5
ENST00000378288.8
TP73
tumor protein p73
chr1_-_56966133 0.59 ENST00000535057.5
ENST00000543257.5
C8B
complement C8 beta chain
chr8_-_71547626 0.57 ENST00000647540.1
ENST00000644229.1
EYA1
EYA transcriptional coactivator and phosphatase 1
chr7_+_120273129 0.57 ENST00000331113.9
KCND2
potassium voltage-gated channel subfamily D member 2
chr10_-_67838173 0.57 ENST00000225171.7
DNAJC12
DnaJ heat shock protein family (Hsp40) member C12
chr15_+_78565556 0.55 ENST00000559554.5
CHRNA5
cholinergic receptor nicotinic alpha 5 subunit
chr5_+_141223332 0.54 ENST00000239449.7
ENST00000624896.1
ENST00000624396.1
PCDHB14
ENSG00000279983.1
protocadherin beta 14
novel protein
chr6_-_79537423 0.54 ENST00000369846.9
ENST00000392959.5
ENST00000467898.3
LCA5
lebercilin LCA5
chr14_+_104801082 0.54 ENST00000342537.8
ZBTB42
zinc finger and BTB domain containing 42
chr10_+_7703300 0.54 ENST00000358415.9
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr15_+_70892809 0.54 ENST00000260382.10
ENST00000560755.5
LRRC49
leucine rich repeat containing 49
chr11_-_122116215 0.53 ENST00000560104.2
BLID
BH3-like motif containing, cell death inducer
chr1_+_86468902 0.52 ENST00000394711.2
CLCA1
chloride channel accessory 1
chr3_+_171843337 0.52 ENST00000334567.9
ENST00000619900.4
ENST00000450693.1
TMEM212
transmembrane protein 212
chr16_+_10386049 0.52 ENST00000562527.5
ENST00000396559.5
ENST00000396560.6
ENST00000562102.5
ENST00000543967.5
ENST00000569939.5
ENST00000569900.5
ATF7IP2
activating transcription factor 7 interacting protein 2
chr9_-_20382461 0.51 ENST00000380321.5
ENST00000629733.3
MLLT3
MLLT3 super elongation complex subunit
chr2_+_98245427 0.50 ENST00000614454.1
VWA3B
von Willebrand factor A domain containing 3B
chr12_-_15221394 0.50 ENST00000537647.5
ENST00000256953.6
ENST00000546331.5
RERG
RAS like estrogen regulated growth inhibitor
chr9_+_117704168 0.50 ENST00000472304.2
ENST00000394487.5
TLR4
toll like receptor 4
chr2_-_212124901 0.50 ENST00000402597.6
ERBB4
erb-b2 receptor tyrosine kinase 4
chr3_-_151203201 0.49 ENST00000480322.1
ENST00000309180.6
GPR171
G protein-coupled receptor 171
chr17_-_31314066 0.49 ENST00000577894.1
EVI2B
ecotropic viral integration site 2B
chr14_+_50872045 0.49 ENST00000337334.7
ABHD12B
abhydrolase domain containing 12B
chr1_-_56966006 0.48 ENST00000371237.9
C8B
complement C8 beta chain
chr14_-_58427134 0.48 ENST00000555930.6
TIMM9
translocase of inner mitochondrial membrane 9
chrX_-_109482075 0.47 ENST00000218006.3
GUCY2F
guanylate cyclase 2F, retinal
chr3_+_148730100 0.47 ENST00000474935.5
ENST00000475347.5
ENST00000461609.1
AGTR1
angiotensin II receptor type 1
chr5_+_140806929 0.47 ENST00000378125.4
ENST00000618834.1
ENST00000530339.2
ENST00000512229.6
ENST00000672575.1
PCDHA4
protocadherin alpha 4
chr4_+_158315309 0.47 ENST00000460056.6
RXFP1
relaxin family peptide receptor 1
chr1_+_3698027 0.47 ENST00000378290.4
TP73
tumor protein p73
chr10_-_121596117 0.46 ENST00000351936.11
FGFR2
fibroblast growth factor receptor 2
chr16_-_28623560 0.45 ENST00000350842.8
SULT1A1
sulfotransferase family 1A member 1
chr1_+_207496268 0.44 ENST00000529814.1
CR1
complement C3b/C4b receptor 1 (Knops blood group)
chr10_-_50279715 0.43 ENST00000395526.9
ASAH2
N-acylsphingosine amidohydrolase 2
chr3_-_109118131 0.43 ENST00000232603.10
MORC1
MORC family CW-type zinc finger 1
chr7_+_123845048 0.43 ENST00000488323.5
ENST00000223026.9
HYAL4
hyaluronidase 4
chr6_-_132659178 0.43 ENST00000275216.3
TAAR1
trace amine associated receptor 1
chr19_+_56176006 0.43 ENST00000357330.7
ENST00000440823.1
GALP
galanin like peptide
chr1_+_246566422 0.43 ENST00000366513.9
ENST00000366512.7
CNST
consortin, connexin sorting protein
chr3_+_174859315 0.40 ENST00000454872.6
NAALADL2
N-acetylated alpha-linked acidic dipeptidase like 2
chr4_-_99290975 0.40 ENST00000209668.3
ADH1A
alcohol dehydrogenase 1A (class I), alpha polypeptide
chr2_-_2326210 0.39 ENST00000647755.1
MYT1L
myelin transcription factor 1 like
chrX_+_49162564 0.39 ENST00000616266.4
MAGIX
MAGI family member, X-linked
chr9_+_105700953 0.39 ENST00000374688.5
TMEM38B
transmembrane protein 38B
chr2_-_127858107 0.39 ENST00000409955.1
ENST00000272645.9
POLR2D
RNA polymerase II subunit D
chr13_-_37869723 0.39 ENST00000426868.6
ENST00000379705.8
ENST00000338947.9
ENST00000355779.6
ENST00000358477.6
ENST00000379673.2
TRPC4
transient receptor potential cation channel subfamily C member 4
chr6_-_152168349 0.39 ENST00000539504.5
SYNE1
spectrin repeat containing nuclear envelope protein 1
chr11_+_27055215 0.39 ENST00000525090.1
BBOX1
gamma-butyrobetaine hydroxylase 1
chr17_+_7583828 0.39 ENST00000396501.8
ENST00000250124.11
ENST00000584378.5
ENST00000423172.6
ENST00000579445.5
ENST00000585217.5
ENST00000581380.1
MPDU1
mannose-P-dolichol utilization defect 1
chrX_-_102380093 0.39 ENST00000604395.5
NXF2B
nuclear RNA export factor 2B
chr10_-_48274567 0.39 ENST00000636244.1
ENST00000374201.8
FRMPD2
FERM and PDZ domain containing 2
chrY_-_23694579 0.38 ENST00000343584.10
PRYP3
PTPN13 like Y-linked pseudogene 3
chr6_-_152168291 0.38 ENST00000354674.5
SYNE1
spectrin repeat containing nuclear envelope protein 1
chr1_+_44405164 0.38 ENST00000355387.6
RNF220
ring finger protein 220
chr17_-_62806632 0.38 ENST00000583803.1
ENST00000456609.6
MARCHF10
membrane associated ring-CH-type finger 10
chr4_-_122621011 0.38 ENST00000611104.2
ENST00000648588.1
IL21
interleukin 21
chr1_+_103617427 0.38 ENST00000423678.2
ENST00000414303.7
AMY2A
amylase alpha 2A
chr6_+_26216928 0.38 ENST00000303910.4
H2AC8
H2A clustered histone 8
chr11_+_60492775 0.37 ENST00000526784.5
ENST00000537076.5
ENST00000016913.8
ENST00000530007.1
MS4A12
membrane spanning 4-domains A12
chr12_+_53985138 0.37 ENST00000303460.5
HOXC10
homeobox C10
chr1_-_230745574 0.37 ENST00000681269.1
AGT
angiotensinogen
chr7_-_122995700 0.37 ENST00000249284.3
TAS2R16
taste 2 receptor member 16
chr6_-_168079159 0.36 ENST00000283309.10
FRMD1
FERM domain containing 1
chr11_-_85686123 0.36 ENST00000316398.5
CCDC89
coiled-coil domain containing 89
chr3_-_58537283 0.36 ENST00000459701.6
ACOX2
acyl-CoA oxidase 2
chr2_+_165239432 0.35 ENST00000636071.2
ENST00000636985.2
SCN2A
sodium voltage-gated channel alpha subunit 2
chr2_-_2326378 0.35 ENST00000647618.1
MYT1L
myelin transcription factor 1 like
chr10_+_94938649 0.34 ENST00000461906.1
ENST00000260682.8
CYP2C9
cytochrome P450 family 2 subfamily C member 9
chr4_+_183905266 0.34 ENST00000308497.9
STOX2
storkhead box 2
chr12_-_10098977 0.34 ENST00000315330.8
ENST00000457018.6
CLEC1A
C-type lectin domain family 1 member A
chr3_-_58537181 0.34 ENST00000302819.10
ACOX2
acyl-CoA oxidase 2
chr1_-_157841800 0.34 ENST00000368174.5
CD5L
CD5 molecule like
chr1_+_196652022 0.34 ENST00000367429.9
ENST00000630130.2
ENST00000359637.2
CFH
complement factor H
chr1_+_103750406 0.33 ENST00000370079.3
AMY1C
amylase alpha 1C
chr7_-_138755892 0.33 ENST00000644341.1
ENST00000478480.2
ATP6V0A4
ATPase H+ transporting V0 subunit a4
chr9_-_83817632 0.33 ENST00000376365.7
ENST00000376371.7
GKAP1
G kinase anchoring protein 1
chr1_-_77219399 0.33 ENST00000359130.1
ENST00000370812.8
ENST00000445065.5
PIGK
phosphatidylinositol glycan anchor biosynthesis class K
chr1_+_61203496 0.33 ENST00000663597.1
NFIA
nuclear factor I A
chr11_-_26572254 0.32 ENST00000529533.6
MUC15
mucin 15, cell surface associated
chrX_+_102307022 0.32 ENST00000604790.2
NXF2
nuclear RNA export factor 2
chr7_-_6059139 0.32 ENST00000446699.1
ENST00000199389.11
EIF2AK1
eukaryotic translation initiation factor 2 alpha kinase 1
chr9_+_78236037 0.31 ENST00000424347.6
ENST00000645398.1
ENST00000643347.1
ENST00000643273.2
ENST00000647199.1
ENST00000643847.1
ENST00000643499.1
ENST00000415759.6
ENST00000376597.9
ENST00000277082.9
ENST00000642669.1
ENST00000642214.1
ENST00000644208.1
ENST00000376598.3
CEP78
centrosomal protein 78
chr2_+_165239388 0.31 ENST00000424833.5
ENST00000375437.7
ENST00000631182.3
SCN2A
sodium voltage-gated channel alpha subunit 2
chr19_+_52336237 0.31 ENST00000403906.8
ENST00000321287.12
ZNF610
zinc finger protein 610
chr3_+_119597874 0.31 ENST00000488919.5
ENST00000273371.9
ENST00000495992.5
PLA1A
phospholipase A1 member A
chr2_-_178702479 0.31 ENST00000414766.5
TTN
titin
chr7_+_6577416 0.31 ENST00000405731.7
ENST00000396713.6
ENST00000396707.6
ENST00000335965.11
ENST00000396709.5
ENST00000483589.5
ENST00000396706.2
ZDHHC4
zinc finger DHHC-type palmitoyltransferase 4
chr19_+_52336260 0.30 ENST00000601151.5
ZNF610
zinc finger protein 610
chr19_-_48110793 0.30 ENST00000599111.5
ENST00000599921.6
PLA2G4C
phospholipase A2 group IVC
chr18_+_58341038 0.30 ENST00000679791.1
NEDD4L
NEDD4 like E3 ubiquitin protein ligase
chr6_-_109009498 0.30 ENST00000356644.7
SESN1
sestrin 1
chr6_-_32666648 0.29 ENST00000399082.7
ENST00000399079.7
ENST00000374943.8
ENST00000434651.6
HLA-DQB1
major histocompatibility complex, class II, DQ beta 1
chrX_+_13655295 0.29 ENST00000380600.1
TCEANC
transcription elongation factor A N-terminal and central domain containing
chr19_-_48110775 0.29 ENST00000354276.7
PLA2G4C
phospholipase A2 group IVC
chr10_-_124093582 0.29 ENST00000462406.1
ENST00000435907.6
CHST15
carbohydrate sulfotransferase 15
chr3_+_124384513 0.29 ENST00000682540.1
ENST00000522553.6
ENST00000682695.1
ENST00000682674.1
ENST00000684382.1
KALRN
kalirin RhoGEF kinase
chr2_+_12716893 0.29 ENST00000381465.2
ENST00000155926.9
TRIB2
tribbles pseudokinase 2
chr2_-_71227055 0.28 ENST00000244221.9
PAIP2B
poly(A) binding protein interacting protein 2B
chr16_-_88706262 0.28 ENST00000562544.1
RNF166
ring finger protein 166
chr11_+_55262152 0.28 ENST00000417545.5
TRIM48
tripartite motif containing 48
chr14_+_88385643 0.28 ENST00000393545.9
ENST00000356583.9
ENST00000555401.5
ENST00000553885.5
SPATA7
spermatogenesis associated 7
chr8_-_100309368 0.28 ENST00000523167.1
RNF19A
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr1_+_174875505 0.28 ENST00000486220.5
RABGAP1L
RAB GTPase activating protein 1 like
chr3_-_150703889 0.28 ENST00000295910.11
ENST00000474463.5
ERICH6
glutamate rich 6
chr3_-_150703943 0.27 ENST00000491361.5
ERICH6
glutamate rich 6
chr1_-_246566238 0.27 ENST00000366514.5
TFB2M
transcription factor B2, mitochondrial
chr6_-_32192845 0.27 ENST00000487761.5
GPSM3
G protein signaling modulator 3
chr14_+_74084947 0.27 ENST00000674221.1
ENST00000554938.2
LIN52
lin-52 DREAM MuvB core complex component
chr15_+_84237586 0.27 ENST00000512109.1
GOLGA6L4
golgin A6 family like 4
chr18_+_58044343 0.26 ENST00000356462.10
ENST00000589054.5
ENST00000617539.1
ENST00000676024.1
ENST00000382850.8
ENST00000256830.13
NEDD4L
NEDD4 like E3 ubiquitin protein ligase
chr3_-_149792547 0.26 ENST00000446160.7
ENST00000462519.3
ANKUB1
ankyrin repeat and ubiquitin domain containing 1
chr3_-_154430184 0.26 ENST00000389740.3
GPR149
G protein-coupled receptor 149
chr10_-_97334698 0.26 ENST00000371019.4
FRAT2
FRAT regulator of WNT signaling pathway 2
chr6_-_32192630 0.26 ENST00000375040.8
GPSM3
G protein signaling modulator 3
chr1_+_174701019 0.25 ENST00000367687.5
ENST00000347255.6
RABGAP1L
RAB GTPase activating protein 1 like
chr17_+_9021501 0.25 ENST00000173229.7
NTN1
netrin 1
chr2_+_108588286 0.25 ENST00000332345.10
LIMS1
LIM zinc finger domain containing 1
chrX_-_48835553 0.25 ENST00000218230.6
PCSK1N
proprotein convertase subtilisin/kexin type 1 inhibitor
chr9_-_13175824 0.25 ENST00000545857.5
MPDZ
multiple PDZ domain crumbs cell polarity complex component
chr1_-_91906280 0.25 ENST00000370399.6
TGFBR3
transforming growth factor beta receptor 3
chr19_-_12610799 0.25 ENST00000311437.11
ZNF490
zinc finger protein 490
chr17_-_19387170 0.25 ENST00000395592.6
ENST00000299610.5
MFAP4
microfibril associated protein 4
chr5_+_161848536 0.25 ENST00000519621.2
ENST00000636573.1
GABRA1
gamma-aminobutyric acid type A receptor subunit alpha1
chr19_-_58150772 0.24 ENST00000597186.5
ENST00000598312.6
ZNF329
zinc finger protein 329
chr4_-_139302460 0.24 ENST00000394223.2
ENST00000676245.1
NDUFC1
NADH:ubiquinone oxidoreductase subunit C1
chr12_-_21775581 0.24 ENST00000537950.1
ENST00000665145.1
KCNJ8
potassium inwardly rectifying channel subfamily J member 8
chr1_-_89126066 0.23 ENST00000370466.4
GBP2
guanylate binding protein 2
chr2_-_55693817 0.23 ENST00000625249.1
ENST00000447944.7
PNPT1
polyribonucleotide nucleotidyltransferase 1
chr15_-_55365231 0.23 ENST00000568543.1
CCPG1
cell cycle progression 1
chr1_-_89270751 0.23 ENST00000370459.7
GBP5
guanylate binding protein 5
chr7_+_90709231 0.22 ENST00000446790.5
ENST00000265741.7
CDK14
cyclin dependent kinase 14
chr9_+_131125578 0.22 ENST00000359428.10
ENST00000411637.6
ENST00000652454.1
NUP214
nucleoporin 214
chr10_+_60778331 0.22 ENST00000519078.6
ENST00000316629.8
ENST00000395284.8
CDK1
cyclin dependent kinase 1
chr19_-_12484773 0.22 ENST00000397732.8
ZNF709
zinc finger protein 709
chr19_-_5978133 0.21 ENST00000340578.10
ENST00000591736.5
ENST00000587479.2
RANBP3
RAN binding protein 3
chr1_+_161153968 0.21 ENST00000368003.6
UFC1
ubiquitin-fold modifier conjugating enzyme 1
chr8_+_99013247 0.21 ENST00000441350.2
ENST00000357162.7
ENST00000358544.7
VPS13B
vacuolar protein sorting 13 homolog B
chr9_+_27109135 0.21 ENST00000519097.5
ENST00000615002.4
TEK
TEK receptor tyrosine kinase
chr1_+_181483541 0.21 ENST00000367570.5
ENST00000621791.4
CACNA1E
calcium voltage-gated channel subunit alpha1 E
chr9_-_21368057 0.21 ENST00000449498.2
IFNA13
interferon alpha 13
chr1_+_241532370 0.21 ENST00000366559.9
ENST00000366557.8
KMO
kynurenine 3-monooxygenase
chr2_+_108607140 0.21 ENST00000410093.5
LIMS1
LIM zinc finger domain containing 1
chr1_+_222928415 0.21 ENST00000284476.7
DISP1
dispatched RND transporter family member 1
chrX_-_123623155 0.21 ENST00000618150.4
THOC2
THO complex 2
chr2_+_61145068 0.21 ENST00000426997.5
ENST00000464909.2
ENST00000489686.5
C2orf74
chromosome 2 open reading frame 74
chr9_+_27109200 0.20 ENST00000380036.10
TEK
TEK receptor tyrosine kinase
chr14_+_58427425 0.20 ENST00000619722.5
ENST00000423743.7
KIAA0586
KIAA0586
chr2_+_113437691 0.20 ENST00000259199.9
ENST00000416503.6
ENST00000433343.6
CBWD2
COBW domain containing 2
chr19_-_50163175 0.20 ENST00000293405.7
IZUMO2
IZUMO family member 2
chr9_+_21440437 0.20 ENST00000276927.3
IFNA1
interferon alpha 1
chr19_-_9435490 0.20 ENST00000592292.5
ENST00000588221.5
ZNF266
zinc finger protein 266
chr8_+_104339796 0.20 ENST00000622554.1
ENST00000297581.2
DCSTAMP
dendrocyte expressed seven transmembrane protein
chr19_+_18097763 0.20 ENST00000262811.10
MAST3
microtubule associated serine/threonine kinase 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0006147 guanine catabolic process(GO:0006147)
0.3 5.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 0.6 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
0.2 1.9 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.2 1.4 GO:0048014 Tie signaling pathway(GO:0048014)
0.2 0.5 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.1 1.8 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 0.4 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.1 0.6 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.1 0.4 GO:0014873 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199) response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.1 0.5 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 0.3 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.1 1.5 GO:0046541 saliva secretion(GO:0046541)
0.1 0.3 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.3 GO:0001546 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.1 1.0 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.1 0.2 GO:0000964 mitochondrial RNA 5'-end processing(GO:0000964) rRNA import into mitochondrion(GO:0035928)
0.1 0.5 GO:0035603 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915)
0.1 0.4 GO:0044026 DNA hypermethylation(GO:0044026)
0.1 0.3 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1 0.8 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.2 GO:0035638 patched ligand maturation(GO:0007225) signal maturation(GO:0035638)
0.1 0.2 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.1 0.6 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 0.2 GO:0060979 transforming growth factor beta receptor complex assembly(GO:0007181) response to luteinizing hormone(GO:0034699) vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.1 0.2 GO:0002316 follicular B cell differentiation(GO:0002316)
0.1 1.1 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.1 0.3 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.1 0.4 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 0.5 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 1.4 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.2 GO:0034241 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241)
0.0 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.3 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.0 0.4 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.7 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 0.1 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.0 0.6 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.5 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.1 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 0.6 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.2 GO:0043335 protein unfolding(GO:0043335)
0.0 0.2 GO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.0 0.1 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.2 GO:1902617 response to fluoride(GO:1902617)
0.0 1.1 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0 0.1 GO:1903217 regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.0 0.1 GO:0090134 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.0 0.5 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.4 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0 0.7 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.6 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.1 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.6 GO:0042424 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0 0.2 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.5 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.2 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.1 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.0 0.3 GO:0060125 habituation(GO:0046959) negative regulation of growth hormone secretion(GO:0060125)
0.0 0.8 GO:0006067 ethanol metabolic process(GO:0006067)
0.0 0.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.6 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 1.1 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.1 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.6 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.2 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.1 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.0 0.3 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.4 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.1 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.4 GO:0006828 manganese ion transport(GO:0006828) gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.9 GO:0071800 podosome assembly(GO:0071800)
0.0 0.4 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.5 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.4 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0090427 egg activation(GO:0007343) activation of meiosis(GO:0090427)
0.0 0.1 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.0 0.2 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.1 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.5 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.7 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.2 GO:0071351 interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.0 0.3 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 0.1 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.1 GO:0033625 positive regulation of integrin activation(GO:0033625)
0.0 0.2 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 1.0 GO:0035036 sperm-egg recognition(GO:0035036)
0.0 0.3 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.1 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0 0.4 GO:0032098 regulation of appetite(GO:0032098)
0.0 0.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.7 GO:0043278 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0 0.1 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.0 1.4 GO:0006968 cellular defense response(GO:0006968)
0.0 0.1 GO:0021914 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0 0.4 GO:0071420 cellular response to histamine(GO:0071420)
0.0 2.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.3 GO:0072189 ureter development(GO:0072189)
0.0 0.1 GO:1902896 terminal web assembly(GO:1902896)
0.0 1.0 GO:0030204 chondroitin sulfate metabolic process(GO:0030204)
0.0 0.1 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.0 0.6 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 1.0 GO:0021795 cerebral cortex cell migration(GO:0021795)
0.0 0.1 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.0 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.1 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 0.7 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.0 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.7 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.0 GO:0036245 cellular response to menadione(GO:0036245)
0.0 0.1 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.1 GO:0051451 myoblast migration(GO:0051451)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.6 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.2 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.1 0.2 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.1 0.3 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.3 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 0.4 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.7 GO:0044292 dendrite terminus(GO:0044292)
0.0 0.4 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.3 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.8 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.2 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.7 GO:0042588 zymogen granule(GO:0042588)
0.0 0.7 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.9 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:0071953 elastic fiber(GO:0071953)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.1 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 1.4 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.3 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.5 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.3 GO:0030914 STAGA complex(GO:0030914)
0.0 2.8 GO:0005814 centriole(GO:0005814)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.3 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 1.2 GO:0045095 keratin filament(GO:0045095)
0.0 7.4 GO:0045121 membrane raft(GO:0045121)
0.0 0.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 1.5 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.1 GO:0035363 histone locus body(GO:0035363)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0046848 hydroxyapatite binding(GO:0046848)
0.3 0.8 GO:0008892 guanine deaminase activity(GO:0008892)
0.2 0.5 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 1.0 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.1 0.7 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.1 0.4 GO:0004877 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
0.1 0.4 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.4 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.3 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.1 0.3 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.1 0.9 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.8 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 1.1 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 0.6 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.4 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.1 0.6 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.3 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.1 0.6 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.1 0.2 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.1 0.2 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.1 0.4 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.1 0.6 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 0.3 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 0.3 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 0.4 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.2 GO:0042008 interleukin-18 receptor activity(GO:0042008)
0.1 0.4 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.6 GO:0008430 selenium binding(GO:0008430)
0.1 0.3 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.4 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.7 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.4 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.4 GO:0071253 connexin binding(GO:0071253)
0.0 0.1 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.0 0.4 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.4 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.9 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.2 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.5 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.5 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.1 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.5 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.5 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
0.0 0.6 GO:0019870 potassium channel inhibitor activity(GO:0019870) sodium channel inhibitor activity(GO:0019871)
0.0 0.7 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0004905 type I interferon receptor activity(GO:0004905)
0.0 0.3 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.2 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.7 GO:0005521 lamin binding(GO:0005521)
0.0 0.4 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.7 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.6 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.3 GO:0031433 telethonin binding(GO:0031433)
0.0 0.2 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.2 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 1.2 GO:0043531 ADP binding(GO:0043531)
0.0 1.2 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.0 0.3 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.6 GO:0019956 chemokine binding(GO:0019956)
0.0 0.5 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.6 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.4 GO:0046961 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.1 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.2 GO:0015197 peptide transporter activity(GO:0015197)
0.0 0.2 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.1 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.7 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.5 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.1 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.1 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.3 PID MYC PATHWAY C-MYC pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.1 0.7 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 0.9 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 0.6 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 1.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.8 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 1.6 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.4 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.4 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.6 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.1 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.7 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.5 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.4 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.7 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.8 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.4 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.2 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP