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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for FOXC1

Z-value: 0.78

Motif logo

Transcription factors associated with FOXC1

Gene Symbol Gene ID Gene Info
ENSG00000054598.9 FOXC1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXC1hg38_v1_chr6_+_1609890_16099320.496.2e-03Click!

Activity profile of FOXC1 motif

Sorted Z-values of FOXC1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXC1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr2_-_72147819 2.60 ENST00000001146.7
ENST00000546307.5
ENST00000474509.1
cytochrome P450 family 26 subfamily B member 1
chr13_-_61415508 1.73 ENST00000409204.4
protocadherin 20
chr2_-_160200289 1.58 ENST00000409872.1
integrin subunit beta 6
chr2_-_160200251 1.41 ENST00000428609.6
ENST00000409967.6
ENST00000283249.7
integrin subunit beta 6
chr9_-_86947496 1.40 ENST00000298743.9
growth arrest specific 1
chr8_-_23404076 1.23 ENST00000524168.1
ENST00000389131.8
ENST00000523833.2
ENST00000519243.1
lysyl oxidase like 2
chr1_-_205455954 1.09 ENST00000495594.2
ENST00000629624.2
LEM domain containing 1
bladder cancer associated transcript 1
chr1_+_12464912 0.98 ENST00000543766.2
vacuolar protein sorting 13 homolog D
chr11_+_114060204 0.95 ENST00000683318.1
zinc finger and BTB domain containing 16
chr8_-_107498041 0.92 ENST00000297450.7
angiopoietin 1
chr8_-_107497909 0.91 ENST00000517746.6
angiopoietin 1
chr13_+_32031706 0.87 ENST00000542859.6
FRY microtubule binding protein
chr11_+_114059755 0.84 ENST00000684295.1
zinc finger and BTB domain containing 16
chr3_-_16482850 0.84 ENST00000432519.5
raftlin, lipid raft linker 1
chr3_+_172754457 0.78 ENST00000441497.6
epithelial cell transforming 2
chr7_+_80602200 0.77 ENST00000534394.5
CD36 molecule
chr7_+_80602150 0.77 ENST00000309881.11
CD36 molecule
chr5_-_73448769 0.74 ENST00000615637.3
forkhead box D1
chr2_+_85753984 0.73 ENST00000306279.4
atonal bHLH transcription factor 8
chr4_-_102345469 0.69 ENST00000356736.5
ENST00000682932.1
solute carrier family 39 member 8
chr8_+_119067239 0.67 ENST00000332843.3
collectin subfamily member 10
chr12_+_59596010 0.66 ENST00000547379.6
ENST00000552432.5
solute carrier family 16 member 7
chr14_+_36657560 0.61 ENST00000402703.6
paired box 9
chr11_-_122116215 0.60 ENST00000560104.2
BH3-like motif containing, cell death inducer
chr21_+_38256698 0.60 ENST00000613499.4
ENST00000612702.4
ENST00000398925.5
ENST00000398928.5
ENST00000328656.8
ENST00000443341.5
potassium inwardly rectifying channel subfamily J member 15
chr13_-_35855627 0.59 ENST00000379893.5
doublecortin like kinase 1
chr3_-_71132099 0.56 ENST00000650188.1
ENST00000648121.1
ENST00000648794.1
ENST00000649592.1
forkhead box P1
chr10_-_67838173 0.55 ENST00000225171.7
DnaJ heat shock protein family (Hsp40) member C12
chr1_+_222928415 0.54 ENST00000284476.7
dispatched RND transporter family member 1
chr6_-_32154326 0.52 ENST00000475826.1
ENST00000485392.5
ENST00000494332.5
ENST00000498575.1
ENST00000428778.5
novel transcript
novel protein
chr9_+_125748175 0.52 ENST00000491787.7
ENST00000447726.6
PBX homeobox 3
chr20_-_63956382 0.51 ENST00000358711.7
ENST00000354216.11
uridine-cytidine kinase 1 like 1
chr7_+_80369547 0.49 ENST00000435819.5
CD36 molecule
chr17_-_39607876 0.47 ENST00000302584.5
neuronal differentiation 2
chr4_-_88823306 0.47 ENST00000395002.6
family with sequence similarity 13 member A
chr2_+_142877653 0.46 ENST00000375773.6
ENST00000409512.5
ENST00000264170.9
ENST00000410015.6
kynureninase
chr10_+_103555124 0.45 ENST00000437579.1
neuralized E3 ubiquitin protein ligase 1
chr12_+_92702843 0.45 ENST00000397833.3
pleckstrin homology and RhoGEF domain containing G7
chr13_+_31945826 0.45 ENST00000647500.1
FRY microtubule binding protein
chr17_-_59151794 0.45 ENST00000584089.1
spindle and kinetochore associated complex subunit 2
chr8_+_69492793 0.44 ENST00000616868.1
ENST00000419716.7
ENST00000402687.9
sulfatase 1
chr8_+_11809135 0.43 ENST00000528643.5
ENST00000525777.5
farnesyl-diphosphate farnesyltransferase 1
chr1_-_93614091 0.43 ENST00000370247.7
BCAR3 adaptor protein, NSP family member
chr7_+_139829242 0.42 ENST00000455353.6
ENST00000458722.6
ENST00000448866.7
ENST00000411653.6
thromboxane A synthase 1
chr21_+_38256984 0.42 ENST00000398938.7
potassium inwardly rectifying channel subfamily J member 15
chr19_-_42427379 0.41 ENST00000244289.9
lipase E, hormone sensitive type
chr7_+_139829153 0.40 ENST00000652056.1
thromboxane A synthase 1
chr12_+_92702983 0.40 ENST00000344636.6
ENST00000544406.2
pleckstrin homology and RhoGEF domain containing G7
chr5_-_128339191 0.39 ENST00000507835.5
fibrillin 2
chr1_-_93847150 0.39 ENST00000370244.5
BCAR3 adaptor protein, NSP family member
chr10_+_52314272 0.38 ENST00000373970.4
dickkopf WNT signaling pathway inhibitor 1
chr10_-_52772763 0.37 ENST00000675947.1
ENST00000674931.1
mannose binding lectin 2
chr5_-_116536458 0.36 ENST00000510263.5
semaphorin 6A
chr4_-_98657635 0.35 ENST00000515287.5
ENST00000511651.5
ENST00000505184.5
tetraspanin 5
chr3_-_71583683 0.35 ENST00000649631.1
ENST00000648718.1
forkhead box P1
chr3_-_71583592 0.35 ENST00000650156.1
ENST00000649596.1
forkhead box P1
chr3_+_156674579 0.34 ENST00000295924.12
TCDD inducible poly(ADP-ribose) polymerase
chr19_-_50637939 0.34 ENST00000338916.8
synaptotagmin 3
chr5_+_162067858 0.34 ENST00000361925.9
gamma-aminobutyric acid type A receptor subunit gamma2
chr5_+_162068031 0.34 ENST00000356592.8
gamma-aminobutyric acid type A receptor subunit gamma2
chr15_-_72271244 0.33 ENST00000287196.13
poly(ADP-ribose) polymerase family member 6
chr19_+_18007182 0.31 ENST00000595712.6
arrestin domain containing 2
chr21_+_36699100 0.31 ENST00000290399.11
SIM bHLH transcription factor 2
chr8_-_133297092 0.31 ENST00000522890.5
ENST00000675983.1
ENST00000518176.5
ENST00000323851.13
ENST00000522476.5
ENST00000518066.5
ENST00000521544.5
ENST00000674605.1
ENST00000518480.5
ENST00000523892.5
N-myc downstream regulated 1
chr4_-_73620391 0.30 ENST00000395777.6
ENST00000307439.10
Ras association domain family member 6
chr1_+_156106698 0.30 ENST00000675667.1
lamin A/C
chr2_-_2326378 0.30 ENST00000647618.1
myelin transcription factor 1 like
chr20_+_59628609 0.30 ENST00000541461.5
phosphatase and actin regulator 3
chr18_+_62715526 0.29 ENST00000262719.10
PH domain and leucine rich repeat protein phosphatase 1
chr1_-_28058087 0.29 ENST00000373864.5
EYA transcriptional coactivator and phosphatase 3
chrX_-_78659328 0.29 ENST00000321110.2
retrotransposon Gag like 3
chr5_-_36241798 0.28 ENST00000514504.5
NAD kinase 2, mitochondrial
chr4_-_185775271 0.28 ENST00000430503.5
ENST00000319454.10
ENST00000450341.5
sorbin and SH3 domain containing 2
chr3_-_187736493 0.28 ENST00000232014.8
BCL6 transcription repressor
chr4_+_77605807 0.28 ENST00000682537.1
C-X-C motif chemokine ligand 13
chr3_+_37990768 0.28 ENST00000383759.7
villin like
chr3_-_169147734 0.27 ENST00000464456.5
MDS1 and EVI1 complex locus
chr16_-_690419 0.27 ENST00000248142.7
WD repeat domain 24
chr16_+_8621717 0.27 ENST00000561758.5
methyltransferase like 22
chr12_-_92145838 0.27 ENST00000256015.5
BTG anti-proliferation factor 1
chr3_-_71581540 0.27 ENST00000650068.1
forkhead box P1
chr8_-_144529048 0.26 ENST00000527462.1
ENST00000313465.5
ENST00000524821.6
chromosome 8 open reading frame 82
chr8_+_96584920 0.26 ENST00000521590.5
syndecan 2
chr14_-_23551729 0.26 ENST00000419474.5
zinc finger homeobox 2
chr7_+_136868622 0.26 ENST00000680005.1
ENST00000445907.6
cholinergic receptor muscarinic 2
chr3_-_71581829 0.26 ENST00000649610.1
forkhead box P1
chr10_+_112950586 0.26 ENST00000355717.9
ENST00000352065.10
ENST00000369395.6
ENST00000545257.6
transcription factor 7 like 2
chr16_-_690387 0.26 ENST00000293883.9
WD repeat domain 24
chr19_-_36032625 0.25 ENST00000593074.5
CAP-Gly domain containing linker protein 3
chr3_+_155080307 0.25 ENST00000360490.7
membrane metalloendopeptidase
chr15_+_75724034 0.25 ENST00000332145.3
outer dense fiber of sperm tails 3 like 1
chr16_+_8621679 0.25 ENST00000563958.5
ENST00000381920.8
ENST00000564554.1
methyltransferase like 22
chr16_-_690247 0.25 ENST00000647644.1
WD repeat domain 24
chr6_+_83853576 0.25 ENST00000369687.2
ripply transcriptional repressor 2
chr19_-_40413364 0.25 ENST00000291825.11
ENST00000324001.8
periaxin
chr5_+_162067764 0.24 ENST00000639213.2
ENST00000414552.6
gamma-aminobutyric acid type A receptor subunit gamma2
chr1_-_159714581 0.24 ENST00000255030.9
ENST00000437342.1
ENST00000368112.5
ENST00000368111.5
ENST00000368110.1
C-reactive protein
chr10_+_80413817 0.24 ENST00000372187.9
peroxiredoxin like 2A
chr18_+_22169580 0.24 ENST00000269216.10
GATA binding protein 6
chr5_+_143812161 0.24 ENST00000289448.4
histocompatibility minor HB-1
chr15_-_78077657 0.24 ENST00000300584.8
ENST00000409931.7
TBC1 domain family member 2B
chr6_+_34236865 0.24 ENST00000674029.1
ENST00000447654.5
ENST00000347617.10
ENST00000401473.7
ENST00000311487.9
high mobility group AT-hook 1
chr2_-_2326210 0.24 ENST00000647755.1
myelin transcription factor 1 like
chr12_-_31326171 0.24 ENST00000542983.1
SIN3-HDAC complex associated factor
chr5_+_162067500 0.23 ENST00000639384.1
ENST00000640985.1
ENST00000638772.1
gamma-aminobutyric acid type A receptor subunit gamma2
chr1_-_153958576 0.23 ENST00000368630.7
ENST00000368633.2
CREB regulated transcription coactivator 2
chr3_+_172040554 0.22 ENST00000336824.8
ENST00000423424.5
fibronectin type III domain containing 3B
chr8_-_71361860 0.22 ENST00000303824.11
ENST00000645451.1
EYA transcriptional coactivator and phosphatase 1
chr13_-_35855758 0.22 ENST00000615680.4
doublecortin like kinase 1
chr6_+_108560906 0.21 ENST00000406360.2
forkhead box O3
chr5_+_162067458 0.21 ENST00000639975.1
ENST00000639111.2
ENST00000639683.1
gamma-aminobutyric acid type A receptor subunit gamma2
chr3_-_187745460 0.21 ENST00000406870.7
BCL6 transcription repressor
chr9_-_4300049 0.21 ENST00000381971.8
GLIS family zinc finger 3
chr20_-_22585451 0.21 ENST00000377115.4
forkhead box A2
chr2_+_28751737 0.21 ENST00000441461.5
ENST00000358506.6
protein phosphatase 1 catalytic subunit beta
chr4_+_85475167 0.21 ENST00000503995.5
Rho GTPase activating protein 24
chr4_-_73620629 0.20 ENST00000342081.7
Ras association domain family member 6
chr8_-_71362054 0.20 ENST00000340726.8
EYA transcriptional coactivator and phosphatase 1
chr20_-_37261808 0.20 ENST00000373614.7
growth hormone releasing hormone
chr7_+_130266847 0.20 ENST00000222481.9
carboxypeptidase A2
chr3_+_57890011 0.20 ENST00000494088.6
ENST00000438794.5
sarcolemma associated protein
chr6_-_110815408 0.20 ENST00000368911.8
cyclin dependent kinase 19
chr11_-_7830840 0.19 ENST00000641167.1
olfactory receptor family 5 subfamily P member 3
chr10_+_68109433 0.19 ENST00000613327.4
ENST00000358913.10
ENST00000373675.3
myopalladin
chr17_+_43211835 0.19 ENST00000588693.5
ENST00000588659.5
ENST00000541594.5
ENST00000536052.5
ENST00000612339.4
transmembrane protein 106A
chr4_-_163613505 0.19 ENST00000339875.9
membrane associated ring-CH-type finger 1
chr6_-_99994173 0.19 ENST00000281806.7
ENST00000369212.2
melanin concentrating hormone receptor 2
chr12_+_10212867 0.19 ENST00000545047.5
ENST00000266458.10
ENST00000629504.1
ENST00000543602.5
ENST00000545887.1
GABA type A receptor associated protein like 1
chr8_-_19682576 0.19 ENST00000332246.10
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr1_-_109393197 0.18 ENST00000538502.5
ENST00000482236.5
sortilin 1
chr6_+_32154131 0.18 ENST00000375143.6
ENST00000324816.11
ENST00000424499.1
palmitoyl-protein thioesterase 2
chr2_+_28751802 0.18 ENST00000296122.10
ENST00000395366.3
protein phosphatase 1 catalytic subunit beta
chr6_+_118894144 0.18 ENST00000229595.6
anti-silencing function 1A histone chaperone
chr12_-_31326142 0.18 ENST00000337682.9
SIN3-HDAC complex associated factor
chr22_-_38302990 0.17 ENST00000612795.2
ENST00000451964.5
casein kinase 1 epsilon
chr16_+_7303245 0.17 ENST00000674626.1
RNA binding fox-1 homolog 1
chr8_-_80080816 0.17 ENST00000520527.5
ENST00000517427.5
ENST00000379097.7
ENST00000448733.3
tumor protein D52
chr22_+_20507571 0.17 ENST00000414658.5
ENST00000432052.5
ENST00000292733.11
ENST00000263205.11
ENST00000406969.5
mediator complex subunit 15
chr3_-_134250831 0.17 ENST00000623711.4
receptor like tyrosine kinase
chr10_+_110225955 0.17 ENST00000239007.11
MAX interactor 1, dimerization protein
chr5_-_111756245 0.17 ENST00000447165.6
neuronal regeneration related protein
chr3_-_71583713 0.17 ENST00000649528.3
ENST00000471386.3
ENST00000493089.7
forkhead box P1
chr4_+_85475131 0.17 ENST00000395184.6
Rho GTPase activating protein 24
chr6_+_138773747 0.17 ENST00000617445.5
coiled-coil domain containing 28A
chr8_-_94436926 0.16 ENST00000481490.3
fibrinogen silencer binding protein
chr9_+_6413191 0.16 ENST00000276893.10
ubiquitin like with PHD and ring finger domains 2
chrX_+_86714623 0.16 ENST00000484479.1
dachshund family transcription factor 2
chr8_-_92095627 0.16 ENST00000517919.5
ENST00000617740.4
ENST00000613302.4
ENST00000436581.6
ENST00000614812.4
ENST00000519847.5
RUNX1 partner transcriptional co-repressor 1
chr4_+_164877164 0.16 ENST00000507152.6
ENST00000515275.1
apelin receptor early endogenous ligand
chr11_-_127000762 0.16 ENST00000525144.7
kirre like nephrin family adhesion molecule 3
chr3_-_71582096 0.16 ENST00000648895.1
forkhead box P1
chr6_+_32154010 0.16 ENST00000375137.6
palmitoyl-protein thioesterase 2
chr2_+_113127588 0.16 ENST00000409930.4
interleukin 1 receptor antagonist
chrX_-_139708190 0.16 ENST00000414978.5
ENST00000519895.5
MCF.2 cell line derived transforming sequence
chr9_-_107489754 0.16 ENST00000610832.1
ENST00000374672.5
Kruppel like factor 4
chr18_+_31591869 0.16 ENST00000237014.8
transthyretin
chr12_+_15956585 0.15 ENST00000526530.1
deoxyribose-phosphate aldolase
chr4_+_70721953 0.15 ENST00000381006.8
ENST00000226328.8
RUN and FYVE domain containing 3
chr12_-_31326111 0.15 ENST00000539409.5
SIN3-HDAC complex associated factor
chr5_-_36241875 0.15 ENST00000381937.9
NAD kinase 2, mitochondrial
chr14_+_69260146 0.15 ENST00000448469.8
polypeptide N-acetylgalactosaminyltransferase 16
chr5_-_36241944 0.15 ENST00000511088.1
ENST00000282512.7
ENST00000506945.5
NAD kinase 2, mitochondrial
chr3_-_20012250 0.15 ENST00000389050.5
protein phosphatase 2C like domain containing 1
chr10_+_112950452 0.15 ENST00000369397.8
transcription factor 7 like 2
chr5_+_76875177 0.14 ENST00000613039.1
S100 calcium binding protein Z
chr8_-_92095215 0.14 ENST00000360348.6
ENST00000520428.5
ENST00000518992.5
ENST00000520556.5
ENST00000518317.5
ENST00000521319.5
ENST00000521375.5
ENST00000518449.5
ENST00000613886.4
RUNX1 partner transcriptional co-repressor 1
chr15_-_41230697 0.14 ENST00000314992.9
ENST00000558396.1
ENST00000458580.7
exonuclease 3'-5' domain containing 1
chr10_-_95441015 0.14 ENST00000371241.5
ENST00000354106.7
ENST00000371239.5
ENST00000361941.7
ENST00000277982.9
ENST00000371245.7
sorbin and SH3 domain containing 1
chr3_-_114178698 0.13 ENST00000467632.5
dopamine receptor D3
chr7_-_87219709 0.13 ENST00000257637.8
transmembrane protein 243
chr10_-_24721866 0.13 ENST00000416305.1
ENST00000320481.10
Rho GTPase activating protein 21
chr8_-_92095598 0.13 ENST00000520724.5
ENST00000518844.5
RUNX1 partner transcriptional co-repressor 1
chr19_+_35533436 0.13 ENST00000222286.9
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr1_+_246566422 0.13 ENST00000366513.9
ENST00000366512.7
consortin, connexin sorting protein
chr8_+_103372388 0.13 ENST00000520337.1
collagen triple helix repeat containing 1
chr15_-_65029576 0.13 ENST00000220058.9
mitochondrial methionyl-tRNA formyltransferase
chr19_-_36032799 0.12 ENST00000592017.5
ENST00000360535.9
CAP-Gly domain containing linker protein 3
chr4_-_115113614 0.12 ENST00000264363.7
N-deacetylase and N-sulfotransferase 4
chr2_-_189179754 0.12 ENST00000374866.9
ENST00000618828.1
collagen type V alpha 2 chain
chr2_-_216013517 0.12 ENST00000263268.11
melanoregulin
chr10_+_112950240 0.12 ENST00000627217.3
ENST00000534894.5
ENST00000538897.5
ENST00000536810.5
ENST00000355995.8
ENST00000542695.5
ENST00000543371.5
transcription factor 7 like 2
chr2_+_167248638 0.12 ENST00000295237.10
xin actin binding repeat containing 2
chr14_-_73558945 0.12 ENST00000563329.1
ENST00000553558.6
ENST00000334988.2
HEAT repeat containing 4
chr11_+_112961247 0.11 ENST00000621518.4
ENST00000618266.4
ENST00000615112.4
ENST00000615285.4
ENST00000619839.4
ENST00000401611.6
ENST00000621128.4
neural cell adhesion molecule 1
chrX_-_11665908 0.11 ENST00000337414.9
Rho GTPase activating protein 6
chr6_-_42048648 0.11 ENST00000502771.1
ENST00000508143.5
ENST00000514588.1
ENST00000510503.5
cyclin D3
chr15_+_75347431 0.11 ENST00000567657.5
nei like DNA glycosylase 1
chr1_-_150010675 0.11 ENST00000417191.2
ENST00000581312.6
OTU deubiquitinase 7B
chr22_+_24432119 0.11 ENST00000472248.5
ENST00000610595.4
ENST00000618076.3
ENST00000436735.1
adenosine A2a receptor
chr12_+_98645218 0.11 ENST00000551964.6
ENST00000333991.5
ENST00000357310.5
ENST00000359972.6
apoptotic peptidase activating factor 1
chr2_-_182242031 0.11 ENST00000358139.6
phosphodiesterase 1A
chr2_+_161160420 0.10 ENST00000392749.7
ENST00000405852.5
TRAF family member associated NFKB activator
chr5_+_160187367 0.10 ENST00000393980.8
fatty acid binding protein 6
chr14_+_69259937 0.10 ENST00000337827.8
polypeptide N-acetylgalactosaminyltransferase 16
chr6_-_56851888 0.10 ENST00000312431.10
ENST00000520645.5
dystonin
chr14_+_50560137 0.10 ENST00000358385.12
atlastin GTPase 1
chr10_+_49299159 0.10 ENST00000374144.8
chromosome 10 open reading frame 71
chr6_+_133953210 0.10 ENST00000367869.1
ENST00000237264.9
ENST00000674115.1
TATA-box binding protein like 1
novel protein
chr14_-_92106535 0.10 ENST00000526872.3
ENST00000532032.5
ENST00000506466.5
ENST00000554592.5
ENST00000555381.5
ENST00000553491.5
ENST00000556220.5
ENST00000557311.6
ENST00000617719.4
ENST00000554672.6
ENST00000644486.2
ENST00000502250.5
ENST00000503767.5
ataxin 3
chr1_+_234373439 0.10 ENST00000366615.10
ENST00000619305.1
cytochrome c oxidase assembly factor 6

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653) regulation of skeletal muscle fiber differentiation(GO:1902809)
0.6 1.8 GO:0035691 macrophage migration inhibitory factor signaling pathway(GO:0035691)
0.3 1.3 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.3 1.8 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.3 3.0 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.2 2.0 GO:2000332 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.2 0.5 GO:0007225 patched ligand maturation(GO:0007225) signal maturation(GO:0035638)
0.1 0.7 GO:0072268 nephrogenic mesenchyme development(GO:0072076) pattern specification involved in metanephros development(GO:0072268)
0.1 0.4 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.4 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.1 2.1 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.5 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.1 0.8 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.1 0.5 GO:0048294 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 0.3 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.1 0.5 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 1.4 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.1 0.5 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.7 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 0.2 GO:0032912 negative regulation of transforming growth factor beta2 production(GO:0032912)
0.1 0.6 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.4 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 0.2 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 0.2 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.1 0.7 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1 0.4 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.2 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.1 0.5 GO:0044211 CTP salvage(GO:0044211)
0.1 0.1 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 0.2 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1 1.0 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.5 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.2 GO:0090134 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.1 0.2 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.1 1.4 GO:0071420 cellular response to histamine(GO:0071420)
0.1 0.3 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.1 0.6 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 0.5 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.2 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.0 0.7 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.0 0.2 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.3 GO:0008218 bioluminescence(GO:0008218)
0.0 0.2 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.0 0.4 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.8 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.8 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.3 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.3 GO:0002667 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.0 1.3 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.0 1.0 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.1 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416) musculoskeletal movement, spinal reflex action(GO:0050883)
0.0 0.1 GO:0036451 cap mRNA methylation(GO:0036451)
0.0 0.2 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.3 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.4 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.0 0.8 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.3 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287) positive regulation of spindle checkpoint(GO:0090232)
0.0 0.3 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.2 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.2 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.0 1.0 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.2 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.1 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 0.2 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.2 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.2 GO:0002118 aggressive behavior(GO:0002118)
0.0 0.1 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.0 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 1.0 GO:0010107 potassium ion import(GO:0010107)
0.0 0.4 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.8 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.2 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
0.0 0.1 GO:0072396 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.0 0.2 GO:0032930 positive regulation of superoxide anion generation(GO:0032930)
0.0 0.1 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.0 0.1 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.5 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880) osteoblast fate commitment(GO:0002051)
0.0 0.0 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.2 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.2 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.1 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.6 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.2 GO:0043970 histone H3-K9 acetylation(GO:0043970)
0.0 0.1 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0 0.1 GO:1990822 L-cystine transport(GO:0015811) basic amino acid transmembrane transport(GO:1990822)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.0 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.1 0.8 GO:0097149 centralspindlin complex(GO:0097149)
0.1 0.2 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.0 2.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.6 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.8 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.3 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.1 GO:0043293 apoptosome(GO:0043293)
0.0 0.4 GO:0042587 glycogen granule(GO:0042587) PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 1.4 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.3 GO:0005638 lamin filament(GO:0005638)
0.0 1.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.5 GO:0097440 apical dendrite(GO:0097440)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 1.7 GO:0005902 microvillus(GO:0005902)
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 1.8 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.3 0.8 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.3 2.0 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.2 0.7 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.2 1.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.4 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 1.8 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.5 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1 0.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 1.4 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 0.4 GO:0017018 myosin phosphatase activity(GO:0017018)
0.1 0.4 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.2 GO:0016608 growth hormone-releasing hormone activity(GO:0016608)
0.1 0.4 GO:0097001 glycosphingolipid binding(GO:0043208) ceramide binding(GO:0097001)
0.1 0.2 GO:0033265 choline binding(GO:0033265)
0.1 0.3 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 1.0 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.2 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.0 0.5 GO:0004849 uridine kinase activity(GO:0004849)
0.0 1.0 GO:0005537 mannose binding(GO:0005537)
0.0 0.4 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.3 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.1 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.2 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.2 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237) glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.2 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.3 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.4 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.5 GO:0015197 peptide transporter activity(GO:0015197)
0.0 0.1 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 3.2 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.8 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.2 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 2.0 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.6 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.0 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.0 0.3 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 1.5 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 1.0 GO:0070888 E-box binding(GO:0070888)
0.0 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.2 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0050436 microfibril binding(GO:0050436)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 1.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.2 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.8 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.9 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.2 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 3.3 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.6 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 1.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.0 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 3.1 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 2.7 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.6 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis