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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for FOXD1_FOXO1_FOXO6_FOXG1_FOXP1

Z-value: 0.87

Motif logo

Transcription factors associated with FOXD1_FOXO1_FOXO6_FOXG1_FOXP1

Gene Symbol Gene ID Gene Info
ENSG00000251493.5 FOXD1
ENSG00000150907.10 FOXO1
ENSG00000204060.7 FOXO6
ENSG00000176165.12 FOXG1
ENSG00000114861.23 FOXP1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXD1hg38_v1_chr5_-_73448769_73448784-0.232.3e-01Click!
FOXP1hg38_v1_chr3_-_71305986_713059980.202.9e-01Click!
FOXO1hg38_v1_chr13_-_40666600_406666500.115.8e-01Click!
FOXG1hg38_v1_chr14_+_28766755_28766802-0.086.9e-01Click!

Activity profile of FOXD1_FOXO1_FOXO6_FOXG1_FOXP1 motif

Sorted Z-values of FOXD1_FOXO1_FOXO6_FOXG1_FOXP1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXD1_FOXO1_FOXO6_FOXG1_FOXP1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_-_161367872 3.61 ENST00000367974.2
cilia and flagella associated protein 126
chr13_-_38990856 2.46 ENST00000423210.1
stomatin like 3
chr13_-_38990824 2.45 ENST00000379631.9
stomatin like 3
chr1_+_20186076 2.28 ENST00000375099.4
UBX domain protein 10
chr17_+_60677822 2.13 ENST00000407086.8
ENST00000589222.5
ENST00000626960.2
ENST00000390652.9
BCAS3 microtubule associated cell migration factor
chr1_-_201127184 1.87 ENST00000449188.3
achaete-scute family bHLH transcription factor 5
chr15_-_60592507 1.80 ENST00000449337.6
RAR related orphan receptor A
chr6_+_151494007 1.79 ENST00000239374.8
coiled-coil domain containing 170
chr3_-_19934189 1.74 ENST00000295824.14
EF-hand domain family member B
chr1_+_161166390 1.70 ENST00000352210.9
ENST00000367999.9
ENST00000497522.5
ENST00000652182.1
ENST00000544598.5
ENST00000535223.5
protoporphyrinogen oxidase
chr11_-_34513750 1.64 ENST00000532417.1
E74 like ETS transcription factor 5
chr9_-_3525968 1.54 ENST00000382004.7
ENST00000617270.5
ENST00000449190.5
regulatory factor X3
chr1_+_226940279 1.54 ENST00000366778.5
ENST00000366777.4
coenzyme Q8A
chr5_+_79236092 1.48 ENST00000396137.5
junction mediating and regulatory protein, p53 cofactor
chr1_+_12746192 1.40 ENST00000614859.5
chromosome 1 open reading frame 158
chr12_-_71157872 1.36 ENST00000546561.2
tetraspanin 8
chr11_+_10455292 1.33 ENST00000396553.6
adenosine monophosphate deaminase 3
chr6_+_135181323 1.31 ENST00000367814.8
MYB proto-oncogene, transcription factor
chr6_+_135181268 1.28 ENST00000341911.10
ENST00000442647.7
ENST00000618728.4
ENST00000316528.12
ENST00000616088.4
MYB proto-oncogene, transcription factor
chr5_+_122129533 1.27 ENST00000296600.5
ENST00000504912.1
ENST00000505843.1
zinc finger protein 474
chr12_-_71157992 1.20 ENST00000247829.8
tetraspanin 8
chr10_+_94089034 1.17 ENST00000676102.1
ENST00000371385.8
phospholipase C epsilon 1
chr10_+_94089067 1.14 ENST00000371375.1
ENST00000675218.1
phospholipase C epsilon 1
chr11_-_34513785 1.12 ENST00000257832.7
ENST00000429939.6
E74 like ETS transcription factor 5
chr2_+_188292771 1.10 ENST00000359135.7
GULP PTB domain containing engulfment adaptor 1
chr13_+_42781578 1.04 ENST00000313851.3
family with sequence similarity 216 member B
chr13_+_42781547 1.03 ENST00000537894.5
family with sequence similarity 216 member B
chr17_-_7044091 1.00 ENST00000574600.3
ENST00000662352.3
ENST00000673828.2
solute carrier family 16 member 11
chr7_+_91940970 1.00 ENST00000359028.7
A-kinase anchoring protein 9
chr3_-_114758940 1.00 ENST00000464560.5
zinc finger and BTB domain containing 20
chr7_+_91940836 0.99 ENST00000680534.1
ENST00000680513.1
ENST00000680072.1
A-kinase anchoring protein 9
chr9_-_81688354 0.99 ENST00000418319.5
TLE family member 1, transcriptional corepressor
chr7_+_91940851 0.98 ENST00000679821.1
ENST00000681722.1
ENST00000680181.1
ENST00000356239.8
ENST00000679521.1
ENST00000680952.1
ENST00000681412.1
ENST00000680766.1
A-kinase anchoring protein 9
chrX_+_38006551 0.97 ENST00000297875.7
synaptotagmin like 5
chr2_-_71227055 0.96 ENST00000244221.9
poly(A) binding protein interacting protein 2B
chr17_-_7043906 0.94 ENST00000308009.5
ENST00000447225.1
solute carrier family 16 member 11
chr3_+_171843337 0.91 ENST00000334567.9
ENST00000619900.4
ENST00000450693.1
transmembrane protein 212
chr3_-_93973833 0.91 ENST00000348974.5
ENST00000647936.1
ENST00000394236.9
ENST00000407433.6
protein S
chr1_+_152514474 0.91 ENST00000368790.4
cysteine rich C-terminal 1
chr3_-_93973933 0.91 ENST00000650591.1
protein S
chr5_+_122129597 0.90 ENST00000514925.1
novel zinc finger protein
chr17_-_76141240 0.88 ENST00000322957.7
forkhead box J1
chr7_+_114414809 0.88 ENST00000350908.9
forkhead box P2
chr9_-_95507416 0.86 ENST00000429896.6
patched 1
chr11_-_115504389 0.84 ENST00000545380.5
ENST00000452722.7
ENST00000331581.11
ENST00000537058.5
ENST00000536727.5
ENST00000542447.6
cell adhesion molecule 1
chr13_+_50015254 0.84 ENST00000360473.8
potassium channel regulator
chr13_+_50015438 0.84 ENST00000312942.2
potassium channel regulator
chr11_-_111910790 0.83 ENST00000533280.6
crystallin alpha B
chr6_+_135181361 0.83 ENST00000527615.5
ENST00000420123.6
ENST00000525369.5
ENST00000528774.5
ENST00000533624.5
ENST00000534044.5
ENST00000534121.5
MYB proto-oncogene, transcription factor
chr11_-_111910830 0.83 ENST00000526167.5
ENST00000651650.1
crystallin alpha B
chr14_-_21025490 0.82 ENST00000553442.5
ENST00000555869.5
ENST00000556457.5
ENST00000397844.6
ENST00000554415.5
ENST00000556974.5
ENST00000554419.5
ENST00000298687.9
ENST00000397858.5
ENST00000360463.7
ENST00000350792.7
ENST00000397847.6
NDRG family member 2
chr1_+_116111395 0.82 ENST00000684484.1
ENST00000369500.4
mab-21 like 3
chr9_-_134068518 0.82 ENST00000371834.6
bromodomain containing 3
chr11_-_111910888 0.81 ENST00000525823.1
ENST00000528961.6
crystallin alpha B
chr14_+_104801082 0.80 ENST00000342537.8
zinc finger and BTB domain containing 42
chr15_-_70702273 0.79 ENST00000558758.5
ENST00000379983.6
ENST00000560441.5
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr14_+_24114627 0.79 ENST00000559115.5
ENST00000558215.5
ENST00000557810.5
ENST00000561375.5
ENST00000446197.8
ENST00000559796.5
ENST00000560713.5
ENST00000560901.5
ENST00000559382.5
ENST00000561001.5
DDB1 and CUL4 associated factor 11
chr7_+_107168961 0.79 ENST00000468410.5
ENST00000478930.5
ENST00000464009.1
ENST00000222574.9
HMG-box transcription factor 1
chr2_+_96816236 0.79 ENST00000377060.7
ENST00000305510.4
cyclin and CBS domain divalent metal cation transport mediator 3
chr16_-_30096170 0.77 ENST00000566134.5
ENST00000565110.5
ENST00000398841.6
ENST00000398838.8
yippee like 3
chr8_-_40897814 0.76 ENST00000297737.11
ENST00000315769.11
zinc finger matrin-type 4
chr7_+_90709816 0.76 ENST00000436577.3
cyclin dependent kinase 14
chr18_+_31318144 0.75 ENST00000257192.5
desmoglein 1
chr11_+_34632464 0.75 ENST00000531794.5
ETS homologous factor
chr1_+_84164684 0.75 ENST00000370680.5
protein kinase cAMP-activated catalytic subunit beta
chr1_-_45491150 0.75 ENST00000372086.4
testis associated actin remodelling kinase 2
chr3_+_113897470 0.75 ENST00000440446.2
ENST00000488680.1
GRAM domain containing 1C
chr14_+_24115299 0.74 ENST00000559354.5
ENST00000560459.5
ENST00000559593.5
ENST00000396941.8
ENST00000396936.5
DDB1 and CUL4 associated factor 11
chr1_+_174964750 0.74 ENST00000367688.3
RAB GTPase activating protein 1 like
chr1_-_145996567 0.72 ENST00000582401.6
thioredoxin interacting protein
chr10_+_110225955 0.72 ENST00000239007.11
MAX interactor 1, dimerization protein
chr17_-_47957824 0.71 ENST00000300557.3
proline rich 15 like
chr3_-_18424533 0.70 ENST00000417717.6
SATB homeobox 1
chr11_-_85686123 0.69 ENST00000316398.5
coiled-coil domain containing 89
chr6_+_138773747 0.69 ENST00000617445.5
coiled-coil domain containing 28A
chr17_+_59331633 0.69 ENST00000312655.9
yippee like 2
chr6_+_162727941 0.68 ENST00000366888.6
parkin coregulated
chr12_+_96194501 0.68 ENST00000552142.5
ETS transcription factor ELK3
chr3_-_114759115 0.68 ENST00000471418.5
zinc finger and BTB domain containing 20
chr7_+_30134956 0.67 ENST00000324453.13
ENST00000409688.1
maturin, neural progenitor differentiation regulator homolog
chr1_-_27490045 0.67 ENST00000536657.1
WASP family member 2
chr2_+_70935919 0.66 ENST00000412314.5
ATPase H+ transporting V1 subunit B1
chr2_-_159616442 0.66 ENST00000541068.6
ENST00000392783.7
ENST00000392782.5
bromodomain adjacent to zinc finger domain 2B
chr2_+_70935864 0.66 ENST00000234396.10
ENST00000454446.6
ATPase H+ transporting V1 subunit B1
chr5_-_16508788 0.64 ENST00000682142.1
reticulophagy regulator 1
chr1_+_246566422 0.64 ENST00000366513.9
ENST00000366512.7
consortin, connexin sorting protein
chr3_+_181711915 0.64 ENST00000325404.3
SRY-box transcription factor 2
chr1_+_24319342 0.64 ENST00000361548.9
grainyhead like transcription factor 3
chr1_+_24319511 0.63 ENST00000356046.6
grainyhead like transcription factor 3
chrX_-_15600953 0.63 ENST00000679212.1
ENST00000679278.1
ENST00000678046.1
ENST00000252519.8
angiotensin I converting enzyme 2
chr3_+_189171948 0.63 ENST00000345063.8
tumor protein p63 regulated 1
chr22_-_31292445 0.62 ENST00000402249.7
ENST00000215912.10
ENST00000443175.1
ENST00000441972.5
phosphoinositide-3-kinase interacting protein 1
chr19_+_49877660 0.60 ENST00000535102.6
TBC1 domain family member 17
chr17_+_59565598 0.60 ENST00000251241.9
ENST00000425628.7
ENST00000584385.5
ENST00000580030.1
DEAH-box helicase 40
chrX_+_49162564 0.60 ENST00000616266.4
MAGI family member, X-linked
chrX_+_71095838 0.59 ENST00000374259.8
forkhead box O4
chr5_-_16508990 0.59 ENST00000399793.6
reticulophagy regulator 1
chr19_+_49877694 0.59 ENST00000221543.10
TBC1 domain family member 17
chr6_-_159045010 0.58 ENST00000338313.5
T cell activation RhoGTPase activating protein
chr2_+_188292814 0.58 ENST00000409580.5
ENST00000409637.7
GULP PTB domain containing engulfment adaptor 1
chr17_-_42745025 0.57 ENST00000592492.5
ENST00000585893.5
ENST00000593214.5
ENST00000590078.5
ENST00000428826.7
ENST00000586382.5
ENST00000415827.6
ENST00000592743.5
ENST00000586089.5
enhancer of zeste 1 polycomb repressive complex 2 subunit
chr19_+_49877425 0.57 ENST00000622860.4
TBC1 domain family member 17
chr3_+_158571171 0.56 ENST00000484955.5
ENST00000359117.9
ENST00000619577.5
ENST00000471745.5
ENST00000477042.6
ENST00000650753.1
ENST00000651984.1
ENST00000355893.11
ENST00000466246.7
ENST00000469452.5
ENST00000482628.5
myeloid leukemia factor 1
chr2_-_233013228 0.56 ENST00000264051.8
neuronal guanine nucleotide exchange factor
chr3_+_158571153 0.56 ENST00000491767.6
ENST00000618075.4
myeloid leukemia factor 1
chr11_+_117178886 0.56 ENST00000620360.4
SID1 transmembrane family member 2
chr10_-_96357155 0.55 ENST00000536387.5
oligodendrocytic myelin paranodal and inner loop protein
chr4_-_151227881 0.55 ENST00000652233.1
ENST00000514152.5
SH3 domain containing 19
chr1_-_217076889 0.54 ENST00000493748.5
ENST00000463665.5
estrogen related receptor gamma
chr16_+_4371840 0.54 ENST00000304735.4
vasorin
chr19_+_12791470 0.53 ENST00000302754.6
JunB proto-oncogene, AP-1 transcription factor subunit
chr7_+_114416286 0.52 ENST00000635534.1
forkhead box P2
chr17_-_8156320 0.52 ENST00000584202.1
ENST00000354903.9
ENST00000577253.5
period circadian regulator 1
chr14_-_21025000 0.52 ENST00000554489.5
ENST00000555657.5
ENST00000557274.5
ENST00000555158.5
ENST00000554833.5
ENST00000555384.5
ENST00000556420.5
ENST00000554893.5
ENST00000553503.5
ENST00000555733.5
ENST00000397856.7
ENST00000553867.5
ENST00000556147.6
ENST00000556008.5
ENST00000557182.5
ENST00000554483.5
ENST00000556688.5
ENST00000397853.7
ENST00000556329.6
ENST00000397851.6
ENST00000554143.5
ENST00000555142.5
ENST00000557676.5
ENST00000556924.5
NDRG family member 2
chr9_+_137230757 0.51 ENST00000673865.1
ENST00000538474.5
ENST00000673835.1
ENST00000673953.1
ENST00000361134.2
solute carrier family 34 member 3
chr5_-_131796921 0.51 ENST00000307968.11
ENST00000307954.12
folliculin interacting protein 1
chr11_-_72794032 0.50 ENST00000334805.11
StAR related lipid transfer domain containing 10
chr11_+_117178728 0.50 ENST00000532960.5
ENST00000324225.9
SID1 transmembrane family member 2
chr7_-_122304738 0.50 ENST00000442488.7
FEZ family zinc finger 1
chr18_+_13218769 0.50 ENST00000677055.1
ENST00000399848.7
low density lipoprotein receptor class A domain containing 4
chr19_-_47231191 0.50 ENST00000439096.3
BCL2 binding component 3
chr14_+_24398986 0.49 ENST00000382554.4
NYN domain and retroviral integrase containing
chr3_-_15797930 0.48 ENST00000683139.1
ankyrin repeat domain 28
chr9_-_37465402 0.48 ENST00000307750.5
zinc finger and BTB domain containing 5
chr2_+_111120906 0.48 ENST00000337565.9
ENST00000357757.6
ENST00000308659.12
ENST00000393256.8
ENST00000610735.4
ENST00000615946.4
ENST00000619294.4
ENST00000620862.4
ENST00000621302.4
ENST00000622509.4
ENST00000622612.4
BCL2 like 11
chr11_+_72080313 0.48 ENST00000307198.11
ENST00000538413.6
ENST00000642648.1
ENST00000289488.7
leucine rich transmembrane and O-methyltransferase domain containing
leucine rich transmembrane and O-methyltransferase domain containing
chr3_+_158571215 0.46 ENST00000498592.6
ENST00000478894.7
myeloid leukemia factor 1
chr5_-_131797030 0.46 ENST00000615660.4
folliculin interacting protein 1
chr11_-_86069811 0.46 ENST00000531930.5
ENST00000528398.5
phosphatidylinositol binding clathrin assembly protein
chr8_+_125430333 0.46 ENST00000311922.4
tribbles pseudokinase 1
chr1_-_179143044 0.46 ENST00000504405.5
ENST00000512653.5
ENST00000344730.7
ABL proto-oncogene 2, non-receptor tyrosine kinase
chr20_-_57266342 0.46 ENST00000395864.7
bone morphogenetic protein 7
chr8_+_26293112 0.45 ENST00000523925.5
ENST00000315985.7
protein phosphatase 2 regulatory subunit Balpha
chr5_-_40755885 0.45 ENST00000636863.1
ENST00000637375.1
ENST00000337702.5
ENST00000636106.1
tetratricopeptide repeat domain 33
chr3_-_15798184 0.45 ENST00000624145.3
ankyrin repeat domain 28
chr1_-_27490130 0.45 ENST00000618852.5
WASP family member 2
chr1_-_152159227 0.44 ENST00000316073.3
repetin
chr17_+_74431338 0.44 ENST00000342648.9
ENST00000652232.1
ENST00000481232.2
G protein-coupled receptor class C group 5 member C
chrX_+_119896157 0.44 ENST00000371422.5
ENST00000334356.2
A-kinase anchoring protein 14
chr19_-_45406327 0.44 ENST00000593226.5
ENST00000418234.6
protein phosphatase 1 regulatory subunit 13 like
chr15_+_98648502 0.43 ENST00000650285.1
ENST00000649865.1
insulin like growth factor 1 receptor
chr4_-_40630588 0.43 ENST00000514014.1
RNA binding motif protein 47
chr21_-_46318199 0.43 ENST00000417060.5
chromosome 21 open reading frame 58
chr1_-_161223408 0.43 ENST00000491350.1
apolipoprotein A2
chrX_+_119895837 0.43 ENST00000371425.8
ENST00000371431.8
A-kinase anchoring protein 14
chr3_+_188212931 0.42 ENST00000618621.4
ENST00000640853.1
LIM domain containing preferred translocation partner in lipoma
chr11_+_117179127 0.42 ENST00000278951.11
SID1 transmembrane family member 2
chr12_+_12611839 0.42 ENST00000228865.3
cAMP responsive element binding protein like 2
chr10_+_91162958 0.42 ENST00000614189.4
polycomb group ring finger 5
chr4_-_122621011 0.42 ENST00000611104.2
ENST00000648588.1
interleukin 21
chrX_-_15601077 0.41 ENST00000680121.1
angiotensin I converting enzyme 2
chr18_-_55589770 0.40 ENST00000565018.6
ENST00000636400.2
transcription factor 4
chr7_-_122304499 0.40 ENST00000427185.2
FEZ family zinc finger 1
chr12_+_130953898 0.40 ENST00000261654.10
adhesion G protein-coupled receptor D1
chr6_+_108656346 0.40 ENST00000540898.1
forkhead box O3
chr2_-_174395640 0.39 ENST00000342016.8
corepressor interacting with RBPJ, CIR1
chr11_-_72793592 0.39 ENST00000536377.5
ENST00000359373.9
StAR related lipid transfer domain containing 10
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr4_+_186227501 0.39 ENST00000446598.6
ENST00000264690.11
ENST00000513864.2
kallikrein B1
chr1_-_1421248 0.39 ENST00000442470.1
ENST00000537107.6
ankyrin repeat domain 65
chr10_-_31928864 0.39 ENST00000375245.8
ENST00000396144.8
Rho GTPase activating protein 12
chr2_+_65056382 0.39 ENST00000377990.7
ENST00000537589.1
ENST00000260569.4
centrosomal protein 68
chr8_-_132760548 0.39 ENST00000519187.5
ENST00000523829.5
ENST00000677595.1
ENST00000356838.7
ENST00000377901.8
ENST00000519304.1
transmembrane protein 71
chr11_-_26572130 0.38 ENST00000527569.1
mucin 15, cell surface associated
chr5_-_16508812 0.37 ENST00000683414.1
reticulophagy regulator 1
chr12_+_6772512 0.37 ENST00000441671.6
ENST00000203629.3
lymphocyte activating 3
chr1_-_114716729 0.37 ENST00000369535.5
NRAS proto-oncogene, GTPase
chr6_-_27912396 0.37 ENST00000303324.4
olfactory receptor family 2 subfamily B member 2
chr4_-_151325488 0.37 ENST00000604030.7
SH3 domain containing 19
chr20_+_64255728 0.37 ENST00000369758.8
ENST00000308824.11
ENST00000609372.1
ENST00000610196.1
ENST00000609764.1
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
chr17_+_81395469 0.36 ENST00000584436.7
BAH domain and coiled-coil containing 1
chr5_+_72956030 0.36 ENST00000430046.7
ENST00000507345.6
ENST00000512348.5
ENST00000287761.7
FCH and mu domain containing endocytic adaptor 2
chr5_-_16508858 0.36 ENST00000684456.1
reticulophagy regulator 1
chr17_+_81395449 0.36 ENST00000675386.2
BAH domain and coiled-coil containing 1
chr15_-_43266857 0.36 ENST00000349114.8
ENST00000220420.10
transglutaminase 5
chr18_+_63907948 0.36 ENST00000238508.8
serpin family B member 10
chr21_-_30216047 0.36 ENST00000399899.2
claudin 8
chr15_-_56465130 0.35 ENST00000260453.4
meiosis specific nuclear structural 1
chr9_+_75890639 0.35 ENST00000545128.5
proprotein convertase subtilisin/kexin type 5
chr18_+_3449620 0.35 ENST00000405385.7
TGFB induced factor homeobox 1
chr10_-_44978789 0.35 ENST00000448778.1
ENST00000298295.4
DEPP1 autophagy regulator
chr2_+_12716893 0.34 ENST00000381465.2
ENST00000155926.9
tribbles pseudokinase 2
chr8_-_123541197 0.34 ENST00000517956.5
ENST00000443022.2
F-box protein 32
chr17_+_39665340 0.34 ENST00000578283.1
ENST00000309889.3
titin-cap
chr3_-_115147277 0.34 ENST00000675478.1
zinc finger and BTB domain containing 20
chr1_-_1421302 0.34 ENST00000520296.5
ankyrin repeat domain 65
chr14_+_50533026 0.34 ENST00000441560.6
atlastin GTPase 1
chr6_-_49744434 0.34 ENST00000433368.6
ENST00000354620.4
cysteine rich secretory protein 3
chr16_+_86578543 0.34 ENST00000320241.5
forkhead box L1
chr9_-_135501734 0.34 ENST00000371791.5
chromosome 9 open reading frame 116
chr4_-_86358487 0.34 ENST00000641066.1
ENST00000512689.6
ENST00000641803.1
ENST00000640970.1
ENST00000641983.1
mitogen-activated protein kinase 10
chr4_+_15374541 0.34 ENST00000382383.7
ENST00000429690.5
C1q and TNF related 7
chr3_-_115147237 0.34 ENST00000357258.8
zinc finger and BTB domain containing 20
chrX_-_31178149 0.34 ENST00000679437.1
dystrophin
chr6_-_49744378 0.33 ENST00000371159.8
ENST00000263045.9
cysteine rich secretory protein 3
chr12_-_70637405 0.33 ENST00000548122.2
ENST00000551525.5
ENST00000550358.5
ENST00000334414.11
protein tyrosine phosphatase receptor type B
chr18_-_55589836 0.33 ENST00000537578.5
ENST00000564403.6
transcription factor 4
chr9_+_131289685 0.33 ENST00000372264.4
phospholipid phosphatase 7 (inactive)
chr10_+_23439060 0.33 ENST00000376495.5
OTU deubiquitinase 1
chr10_+_30434021 0.32 ENST00000542547.5
mitogen-activated protein kinase kinase kinase 8
chr5_-_16508951 0.32 ENST00000682628.1
reticulophagy regulator 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.5 1.6 GO:0021757 caudate nucleus development(GO:0021757) putamen development(GO:0021758)
0.5 1.5 GO:0002071 glandular epithelial cell maturation(GO:0002071) positive regulation of type B pancreatic cell development(GO:2000078)
0.4 2.8 GO:0001712 ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712)
0.3 2.3 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.3 1.5 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.3 2.3 GO:0061709 reticulophagy(GO:0061709)
0.3 1.1 GO:0010157 response to chlorate(GO:0010157)
0.2 0.5 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.2 1.1 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.2 1.3 GO:0006196 AMP catabolic process(GO:0006196)
0.2 3.0 GO:0051661 maintenance of centrosome location(GO:0051661)
0.2 1.2 GO:0002005 angiotensin catabolic process in blood(GO:0002005)
0.2 0.6 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.2 0.7 GO:1905069 nephrogenic mesenchyme morphogenesis(GO:0072134) allantois development(GO:1905069)
0.2 0.5 GO:1990785 response to water-immersion restraint stress(GO:1990785)
0.2 1.3 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.2 0.5 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.1 2.5 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 1.5 GO:0033227 dsRNA transport(GO:0033227)
0.1 0.8 GO:0031438 negative regulation of mRNA cleavage(GO:0031438) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.1 0.8 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 1.8 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1 0.5 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.1 0.9 GO:0072139 metanephric part of ureteric bud development(GO:0035502) negative regulation of interleukin-6 biosynthetic process(GO:0045409) glomerular parietal epithelial cell differentiation(GO:0072139)
0.1 0.3 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1 0.9 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.3 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1 0.4 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.1 0.8 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.1 0.3 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 0.4 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.1 1.8 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 1.7 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.1 0.5 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.3 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 1.6 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.1 0.3 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.5 GO:0097167 circadian regulation of translation(GO:0097167)
0.1 0.4 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.1 0.3 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1 0.6 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.2 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.1 0.2 GO:0007518 myoblast fate determination(GO:0007518)
0.1 1.3 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 0.6 GO:0002001 renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999) renin secretion into blood stream(GO:0002001) nerve growth factor processing(GO:0032455)
0.1 0.6 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.4 GO:0001777 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.6 GO:0001714 endodermal cell fate specification(GO:0001714)
0.1 0.5 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.5 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 0.3 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.1 0.2 GO:0035565 regulation of pronephros size(GO:0035565)
0.1 0.3 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.1 0.3 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.1 1.3 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 0.3 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 0.8 GO:0032782 bile acid secretion(GO:0032782)
0.1 0.3 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1 0.2 GO:1903248 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.1 0.5 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 0.1 GO:0044266 multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266)
0.1 0.1 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
0.1 0.5 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 0.2 GO:0015917 aminophospholipid transport(GO:0015917)
0.1 0.4 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 0.2 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.1 0.3 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.1 1.5 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.6 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.1 0.6 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.1 0.7 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 1.1 GO:0031507 heterochromatin assembly(GO:0031507)
0.1 0.3 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.1 0.2 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.0 0.6 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.5 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 2.2 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 1.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.5 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 1.1 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.2 GO:0021590 cerebellum maturation(GO:0021590) cerebellar Purkinje cell layer maturation(GO:0021691) cerebellar cortex maturation(GO:0021699)
0.0 0.3 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 1.0 GO:0002347 response to tumor cell(GO:0002347)
0.0 0.2 GO:1902617 response to fluoride(GO:1902617)
0.0 0.3 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.1 GO:0097325 melanocyte proliferation(GO:0097325)
0.0 0.9 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.3 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.1 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.4 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.1 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.0 2.1 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.2 GO:2000690 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0 0.2 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.2 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.0 0.1 GO:0061055 myotome development(GO:0061055)
0.0 0.1 GO:0090285 regulation of protein glycosylation in Golgi(GO:0090283) negative regulation of protein glycosylation in Golgi(GO:0090285)
0.0 0.2 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.2 GO:0030070 insulin processing(GO:0030070)
0.0 0.3 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.2 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 0.4 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0 0.2 GO:0002353 kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.0 2.1 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.5 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:0018032 protein amidation(GO:0018032)
0.0 0.4 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.2 GO:0035604 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development(GO:0035607) fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915)
0.0 0.7 GO:0060117 auditory receptor cell development(GO:0060117)
0.0 1.1 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.1 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.3 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.1 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.0 0.5 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.2 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.0 0.2 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 0.0 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.0 0.2 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.1 GO:2000910 negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
0.0 0.8 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.1 GO:0035048 splicing factor protein import into nucleus(GO:0035048)
0.0 0.1 GO:1990654 regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
0.0 0.5 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.8 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.2 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.2 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.2 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.2 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.1 GO:1990535 neuron projection maintenance(GO:1990535)
0.0 2.6 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.4 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.7 GO:2000811 negative regulation of anoikis(GO:2000811)
0.0 0.4 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.3 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.2 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.2 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.5 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 0.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.4 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.2 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.2 GO:0071073 positive regulation of phospholipid biosynthetic process(GO:0071073)
0.0 0.3 GO:0035878 nail development(GO:0035878)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.1 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.2 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.1 GO:0090133 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.2 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.0 GO:0060932 His-Purkinje system cell differentiation(GO:0060932)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 3.1 GO:0044782 cilium organization(GO:0044782)
0.0 0.2 GO:0036315 cellular response to sterol(GO:0036315)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.1 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.2 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.2 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.5 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.0 GO:0060596 mammary placode formation(GO:0060596)
0.0 0.1 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.2 GO:0072189 ureter development(GO:0072189)
0.0 0.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.9 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.8 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0035864 response to potassium ion(GO:0035864)
0.0 0.4 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.1 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.2 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.2 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.1 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.0 GO:0001842 neural fold formation(GO:0001842)
0.0 0.2 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.1 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.0 0.0 GO:0060594 mammary gland specification(GO:0060594)
0.0 0.1 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.0 0.0 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.0 0.4 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.0 0.2 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.1 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.0 0.6 GO:0008088 axo-dendritic transport(GO:0008088)
0.0 0.8 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.3 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.6 GO:0051646 mitochondrion localization(GO:0051646)
0.0 0.3 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.0 0.9 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.0 GO:0044307 dendritic branch(GO:0044307)
0.2 2.5 GO:0097512 cardiac myofibril(GO:0097512)
0.1 1.1 GO:0044294 dendritic growth cone(GO:0044294)
0.1 0.8 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 0.3 GO:0034657 GID complex(GO:0034657)
0.1 1.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 0.5 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 1.1 GO:0031209 SCAR complex(GO:0031209)
0.1 2.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 0.3 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 1.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 1.1 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 2.1 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 0.6 GO:0035976 AP1 complex(GO:0035976)
0.1 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.5 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1 0.6 GO:0097427 microtubule bundle(GO:0097427)
0.0 1.7 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 1.9 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.3 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.5 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.2 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.7 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.7 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 2.4 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 1.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.6 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 3.0 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.2 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 2.1 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.1 GO:0001534 radial spoke(GO:0001534)
0.0 0.1 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.8 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 1.8 GO:0005776 autophagosome(GO:0005776)
0.0 0.0 GO:0070939 Dsl1p complex(GO:0070939)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.1 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 2.5 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.5 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.1 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 2.7 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.5 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.8 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.3 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.4 GO:0034364 high-density lipoprotein particle(GO:0034364)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.3 2.0 GO:0008142 oxysterol binding(GO:0008142)
0.3 3.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.3 1.5 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.2 1.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.2 1.1 GO:0005119 smoothened binding(GO:0005119) hedgehog family protein binding(GO:0097108)
0.2 1.0 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.2 0.8 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 1.3 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.4 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 1.7 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1 1.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.8 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 0.7 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 1.9 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 2.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.7 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 0.2 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.1 0.4 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.3 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.1 0.2 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.1 0.6 GO:0071253 connexin binding(GO:0071253)
0.1 0.2 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.1 0.2 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.1 0.3 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.4 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 0.2 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 0.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.4 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.7 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.5 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.1 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.5 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.1 0.7 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.3 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.3 GO:0051373 FATZ binding(GO:0051373)
0.0 0.2 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 1.9 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.2 GO:0030226 apolipoprotein receptor activity(GO:0030226)
0.0 0.2 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.0 0.4 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.0 0.7 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 0.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.0 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.2 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.0 0.2 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.7 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 1.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.2 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.5 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.5 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:0008513 secondary active organic cation transmembrane transporter activity(GO:0008513)
0.0 0.1 GO:0055100 adiponectin binding(GO:0055100)
0.0 0.1 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 0.1 GO:0004577 N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity(GO:0004577)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.3 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.6 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 1.9 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.5 GO:0048156 tau protein binding(GO:0048156)
0.0 0.2 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 1.5 GO:0043531 ADP binding(GO:0043531)
0.0 0.4 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.7 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 5.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.6 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 2.5 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.5 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.1 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.0 0.8 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.1 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 3.7 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.6 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.4 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0004096 catalase activity(GO:0004096)
0.0 0.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.2 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 1.0 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.3 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.4 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 4.4 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 2.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.7 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.1 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.8 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.4 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 2.3 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.2 PID FOXO PATHWAY FoxO family signaling
0.0 2.8 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.5 PID IGF1 PATHWAY IGF1 pathway
0.0 0.6 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.8 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 3.1 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 1.7 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.9 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.2 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.6 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.9 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.4 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.8 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.3 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 1.1 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.1 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.4 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.5 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 1.3 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.1 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.3 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.9 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus