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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for GAGGUAG

Z-value: 1.29

Motif logo

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miRNA associated with seed GAGGUAG

NamemiRBASE accession
hsa-let-7a-5p
MIMAT0000062
hsa-let-7b-5p
MIMAT0000063
hsa-let-7c-5p
MIMAT0000064
hsa-let-7d-5p
MIMAT0000065
hsa-let-7e-5p
MIMAT0000066
hsa-let-7f-5p
MIMAT0000067
hsa-let-7g-5p
MIMAT0000414
hsa-let-7i-5p
MIMAT0000415
hsa-miR-4458
MIMAT0018980
hsa-miR-4500
MIMAT0019036
hsa-miR-98-5p
MIMAT0000096

Activity profile of GAGGUAG motif

Sorted Z-values of GAGGUAG motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GAGGUAG

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr12_-_24949026 5.21 ENST00000539780.5
ENST00000546285.1
ENST00000342945.9
ENST00000261192.12
BCAT1
branched chain amino acid transaminase 1
chr1_+_152514474 4.64 ENST00000368790.4
CRCT1
cysteine rich C-terminal 1
chr2_-_1744442 4.35 ENST00000433670.5
ENST00000425171.1
ENST00000252804.9
PXDN
peroxidasin
chr19_+_6531018 3.57 ENST00000245817.5
TNFSF9
TNF superfamily member 9
chrX_-_108438407 3.51 ENST00000334504.12
ENST00000621266.4
ENST00000538570.5
ENST00000394872.6
ENST00000545689.2
COL4A6
collagen type IV alpha 6 chain
chr12_+_4273751 3.51 ENST00000675880.1
ENST00000261254.8
CCND2
cyclin D2
chr9_+_128411715 3.48 ENST00000420034.5
ENST00000372842.5
CERCAM
cerebral endothelial cell adhesion molecule
chr1_-_9129085 3.40 ENST00000377411.5
GPR157
G protein-coupled receptor 157
chr7_-_23470469 3.30 ENST00000258729.8
IGF2BP3
insulin like growth factor 2 mRNA binding protein 3
chr21_-_26845402 3.24 ENST00000284984.8
ENST00000676955.1
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr12_+_65824475 3.21 ENST00000403681.7
HMGA2
high mobility group AT-hook 2
chr5_-_140346596 2.96 ENST00000230990.7
HBEGF
heparin binding EGF like growth factor
chr5_+_157460173 2.90 ENST00000435489.7
ENST00000311946.8
NIPAL4
NIPA like domain containing 4
chr13_+_110307276 2.88 ENST00000360467.7
ENST00000650540.1
COL4A2
collagen type IV alpha 2 chain
chr10_+_100347225 2.80 ENST00000370355.3
SCD
stearoyl-CoA desaturase
chr1_-_28176665 2.74 ENST00000373857.8
PTAFR
platelet activating factor receptor
chr15_+_39581068 2.71 ENST00000397591.2
ENST00000260356.6
THBS1
thrombospondin 1
chr1_+_15409858 2.69 ENST00000375980.9
EFHD2
EF-hand domain family member D2
chr12_-_68933161 2.66 ENST00000549781.1
ENST00000551568.6
ENST00000548262.5
CPM
carboxypeptidase M
chr17_+_43398984 2.56 ENST00000320033.5
ARL4D
ADP ribosylation factor like GTPase 4D
chr5_+_38846002 2.42 ENST00000274276.8
OSMR
oncostatin M receptor
chr1_-_204151884 2.38 ENST00000367201.7
ETNK2
ethanolamine kinase 2
chr20_-_5610980 2.37 ENST00000379019.7
GPCPD1
glycerophosphocholine phosphodiesterase 1
chr6_+_34236865 2.34 ENST00000674029.1
ENST00000447654.5
ENST00000347617.10
ENST00000401473.7
ENST00000311487.9
HMGA1
high mobility group AT-hook 1
chr2_-_189179754 2.30 ENST00000374866.9
ENST00000618828.1
COL5A2
collagen type V alpha 2 chain
chr7_+_101154445 2.21 ENST00000337619.11
ENST00000429457.1
AP1S1
adaptor related protein complex 1 subunit sigma 1
chr12_+_1691011 2.14 ENST00000357103.5
ADIPOR2
adiponectin receptor 2
chr11_+_130448633 2.09 ENST00000299164.4
ADAMTS15
ADAM metallopeptidase with thrombospondin type 1 motif 15
chr2_+_200811882 2.04 ENST00000409600.6
BZW1
basic leucine zipper and W2 domains 1
chr8_-_143541425 2.03 ENST00000262577.6
ZC3H3
zinc finger CCCH-type containing 3
chr3_-_86991135 1.98 ENST00000398399.7
VGLL3
vestigial like family member 3
chr9_-_69672341 1.90 ENST00000265381.7
APBA1
amyloid beta precursor protein binding family A member 1
chr6_+_36678699 1.89 ENST00000405375.5
ENST00000244741.10
ENST00000373711.3
CDKN1A
cyclin dependent kinase inhibitor 1A
chr8_-_29350666 1.88 ENST00000240100.7
DUSP4
dual specificity phosphatase 4
chr2_+_74834113 1.83 ENST00000290573.7
HK2
hexokinase 2
chr6_+_106098933 1.82 ENST00000369089.3
PRDM1
PR/SET domain 1
chr16_+_2429427 1.81 ENST00000397066.9
CCNF
cyclin F
chr20_+_6767678 1.81 ENST00000378827.5
BMP2
bone morphogenetic protein 2
chr1_+_37692506 1.76 ENST00000373055.6
CDCA8
cell division cycle associated 8
chr20_-_47786553 1.73 ENST00000467815.5
ENST00000359930.8
ENST00000484875.5
SULF2
sulfatase 2
chr22_+_37051731 1.71 ENST00000610767.4
ENST00000402077.7
ENST00000403888.7
KCTD17
potassium channel tetramerization domain containing 17
chr3_-_52056552 1.64 ENST00000495880.2
DUSP7
dual specificity phosphatase 7
chr19_+_926001 1.64 ENST00000263620.8
ARID3A
AT-rich interaction domain 3A
chr1_-_153390976 1.62 ENST00000368732.5
ENST00000368733.4
S100A8
S100 calcium binding protein A8
chr13_-_30307539 1.62 ENST00000380615.8
KATNAL1
katanin catalytic subunit A1 like 1
chr2_+_10122315 1.59 ENST00000360566.6
RRM2
ribonucleotide reductase regulatory subunit M2
chr14_-_52695543 1.59 ENST00000395686.8
ERO1A
endoplasmic reticulum oxidoreductase 1 alpha
chr3_+_49171590 1.58 ENST00000332780.4
KLHDC8B
kelch domain containing 8B
chr6_+_12290353 1.58 ENST00000379375.6
EDN1
endothelin 1
chr12_+_56521798 1.56 ENST00000262031.10
RBMS2
RNA binding motif single stranded interacting protein 2
chr1_+_203626775 1.52 ENST00000367218.7
ATP2B4
ATPase plasma membrane Ca2+ transporting 4
chr18_-_12658052 1.49 ENST00000409402.8
SPIRE1
spire type actin nucleation factor 1
chrX_+_65667645 1.49 ENST00000360270.7
MSN
moesin
chr14_+_75002903 1.48 ENST00000266126.10
EIF2B2
eukaryotic translation initiation factor 2B subunit beta
chr17_-_50201618 1.45 ENST00000225964.10
COL1A1
collagen type I alpha 1 chain
chr1_+_230067198 1.45 ENST00000366672.5
GALNT2
polypeptide N-acetylgalactosaminyltransferase 2
chr19_+_531750 1.43 ENST00000215574.9
CDC34
cell division cycle 34, ubiqiutin conjugating enzyme
chr7_-_24980148 1.40 ENST00000313367.7
OSBPL3
oxysterol binding protein like 3
chr2_+_69915100 1.40 ENST00000264444.7
MXD1
MAX dimerization protein 1
chr15_-_45522747 1.39 ENST00000261867.5
SLC30A4
solute carrier family 30 member 4
chr5_-_132227808 1.36 ENST00000401867.5
ENST00000379086.5
ENST00000379100.7
ENST00000418055.5
ENST00000453286.5
ENST00000360568.8
ENST00000379104.7
ENST00000166534.8
P4HA2
prolyl 4-hydroxylase subunit alpha 2
chr12_-_109477293 1.35 ENST00000228495.11
ENST00000542858.1
ENST00000542262.5
KCTD10
potassium channel tetramerization domain containing 10
chr3_-_185498964 1.35 ENST00000296254.3
TMEM41A
transmembrane protein 41A
chr6_+_41638438 1.35 ENST00000441667.5
ENST00000230321.11
ENST00000373050.8
ENST00000446650.1
ENST00000435476.1
MDFI
MyoD family inhibitor
chr6_-_32190170 1.33 ENST00000375050.6
PBX2
PBX homeobox 2
chr21_-_41508146 1.29 ENST00000679054.1
ENST00000678348.1
ENST00000332149.10
ENST00000679016.1
ENST00000678743.1
ENST00000678171.1
ENST00000458356.6
TMPRSS2
transmembrane serine protease 2
chr9_-_35115839 1.28 ENST00000378566.5
ENST00000322813.10
FAM214B
family with sequence similarity 214 member B
chr15_+_63189554 1.28 ENST00000559006.1
ENST00000321437.9
RAB8B
RAB8B, member RAS oncogene family
chr14_+_24398986 1.28 ENST00000382554.4
NYNRIN
NYN domain and retroviral integrase containing
chr17_+_42020079 1.28 ENST00000393885.9
ENST00000393880.5
ENST00000393881.7
ENST00000462043.6
ENST00000449471.8
ENST00000316082.4
NKIRAS2
NFKB inhibitor interacting Ras like 2
chr6_+_46652968 1.27 ENST00000371347.10
SLC25A27
solute carrier family 25 member 27
chr13_-_33285682 1.25 ENST00000336934.10
STARD13
StAR related lipid transfer domain containing 13
chr14_-_34713788 1.25 ENST00000341223.8
CFL2
cofilin 2
chr15_+_74541200 1.23 ENST00000622429.1
ENST00000346246.10
ARID3B
AT-rich interaction domain 3B
chr16_+_397183 1.20 ENST00000620944.4
ENST00000621774.4
ENST00000219479.7
NME4
NME/NM23 nucleoside diphosphate kinase 4
chr5_-_55712280 1.19 ENST00000506624.5
ENST00000513275.5
ENST00000513993.5
ENST00000396865.7
ENST00000503891.5
ENST00000507109.5
SLC38A9
solute carrier family 38 member 9
chr3_+_150408314 1.19 ENST00000361875.7
TSC22D2
TSC22 domain family member 2
chr11_+_119206298 1.17 ENST00000634586.1
ENST00000634840.1
ENST00000264033.6
ENST00000637974.1
CBL
Cbl proto-oncogene
chr7_+_76461676 1.17 ENST00000425780.5
ENST00000456590.5
ENST00000451769.5
ENST00000324432.9
ENST00000457529.5
ENST00000446600.5
ENST00000430490.7
ENST00000413936.6
ENST00000423646.5
ENST00000438930.5
DTX2
deltex E3 ubiquitin ligase 2
chr9_+_125747345 1.15 ENST00000342287.9
ENST00000373489.10
ENST00000373487.8
PBX3
PBX homeobox 3
chr5_-_64768619 1.14 ENST00000513458.9
SREK1IP1
SREK1 interacting protein 1
chr1_+_154405193 1.13 ENST00000622330.4
ENST00000344086.8
IL6R
interleukin 6 receptor
chr3_-_16264891 1.12 ENST00000488423.2
ENST00000383775.4
DPH3
diphthamide biosynthesis 3
chr3_+_172040554 1.12 ENST00000336824.8
ENST00000423424.5
FNDC3B
fibronectin type III domain containing 3B
chr2_+_17541157 1.11 ENST00000406397.1
VSNL1
visinin like 1
chr11_+_63813384 1.09 ENST00000294244.9
SPINDOC
spindlin interactor and repressor of chromatin binding
chr3_+_122055355 1.07 ENST00000330540.7
ENST00000469710.5
ENST00000493101.5
CD86
CD86 molecule
chrX_+_56232343 1.05 ENST00000468660.6
KLF8
Kruppel like factor 8
chr10_+_123666355 1.04 ENST00000284674.2
GPR26
G protein-coupled receptor 26
chr15_+_90001300 1.03 ENST00000268154.9
ZNF710
zinc finger protein 710
chr8_-_130443581 1.01 ENST00000357668.2
ENST00000518721.6
ASAP1
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr9_+_123356189 1.01 ENST00000373631.8
CRB2
crumbs cell polarity complex component 2
chr2_-_230068905 1.00 ENST00000457406.5
ENST00000295190.9
SLC16A14
solute carrier family 16 member 14
chr17_+_7439504 0.97 ENST00000575331.1
ENST00000293829.9
ENSG00000272884.1
FGF11
novel transcript
fibroblast growth factor 11
chr20_-_49915509 0.96 ENST00000289431.10
SPATA2
spermatogenesis associated 2
chr19_+_33796846 0.96 ENST00000590771.5
ENST00000589786.5
ENST00000284006.10
ENST00000683859.1
ENST00000588881.5
KCTD15
potassium channel tetramerization domain containing 15
chr1_-_23800402 0.95 ENST00000374497.7
ENST00000425913.5
GALE
UDP-galactose-4-epimerase
chr6_+_11093753 0.94 ENST00000416247.4
SMIM13
small integral membrane protein 13
chr3_+_196867856 0.93 ENST00000445299.6
ENST00000323460.10
ENST00000419026.5
SENP5
SUMO specific peptidase 5
chr19_+_45079195 0.93 ENST00000591607.1
ENST00000591747.5
ENST00000270257.9
ENST00000391951.2
ENST00000587566.5
GEMIN7
MARK4
gem nuclear organelle associated protein 7
microtubule affinity regulating kinase 4
chr3_+_102435015 0.91 ENST00000306176.5
ENST00000466937.2
ZPLD1
zona pellucida like domain containing 1
chr2_+_74654228 0.91 ENST00000611975.4
ENST00000357877.7
ENST00000339773.9
ENST00000434486.5
SEMA4F
ssemaphorin 4F
chrX_-_7148118 0.91 ENST00000486446.3
ENST00000381077.10
ENST00000412827.6
ENST00000424830.6
PUDP
pseudouridine 5'-phosphatase
chr15_+_45587366 0.91 ENST00000220531.9
BLOC1S6
biogenesis of lysosomal organelles complex 1 subunit 6
chr9_-_74952904 0.91 ENST00000376854.6
C9orf40
chromosome 9 open reading frame 40
chr8_+_125430333 0.91 ENST00000311922.4
TRIB1
tribbles pseudokinase 1
chr8_-_123541197 0.90 ENST00000517956.5
ENST00000443022.2
FBXO32
F-box protein 32
chr11_-_12009082 0.90 ENST00000396505.7
DKK3
dickkopf WNT signaling pathway inhibitor 3
chr9_+_75088498 0.90 ENST00000346234.7
OSTF1
osteoclast stimulating factor 1
chr20_-_34112205 0.89 ENST00000374980.3
EIF2S2
eukaryotic translation initiation factor 2 subunit beta
chr1_+_100266195 0.86 ENST00000370128.9
ENST00000260563.4
RTCA
RNA 3'-terminal phosphate cyclase
chr11_+_69641146 0.86 ENST00000227507.3
ENST00000536559.1
CCND1
cyclin D1
chr3_-_48188356 0.86 ENST00000351231.7
ENST00000437972.1
ENST00000302506.8
CDC25A
cell division cycle 25A
chr1_-_119648165 0.86 ENST00000421812.3
ZNF697
zinc finger protein 697
chr22_-_35840218 0.86 ENST00000414461.6
ENST00000416721.6
ENST00000449924.6
ENST00000262829.11
ENST00000397305.3
RBFOX2
RNA binding fox-1 homolog 2
chr22_-_39244969 0.85 ENST00000331163.11
PDGFB
platelet derived growth factor subunit B
chr15_+_81000913 0.85 ENST00000267984.4
TLNRD1
talin rod domain containing 1
chr9_-_70414657 0.84 ENST00000377126.4
KLF9
Kruppel like factor 9
chr19_+_13952466 0.83 ENST00000254337.10
DCAF15
DDB1 and CUL4 associated factor 15
chr5_-_172771187 0.83 ENST00000239223.4
DUSP1
dual specificity phosphatase 1
chr12_-_12562851 0.82 ENST00000298573.9
DUSP16
dual specificity phosphatase 16
chr1_+_204073104 0.81 ENST00000367204.6
SOX13
SRY-box transcription factor 13
chr1_+_167630093 0.81 ENST00000537350.5
ENST00000361496.3
ENST00000367854.8
RCSD1
RCSD domain containing 1
chr5_+_157743703 0.80 ENST00000286307.6
LSM11
LSM11, U7 small nuclear RNA associated
chr15_+_88621290 0.80 ENST00000332810.4
ENST00000559528.1
AEN
apoptosis enhancing nuclease
chr3_-_185825029 0.80 ENST00000382199.7
IGF2BP2
insulin like growth factor 2 mRNA binding protein 2
chr9_+_116153783 0.79 ENST00000328252.4
PAPPA
pappalysin 1
chr3_-_33096794 0.79 ENST00000416695.6
ENST00000399402.7
TMPPE
GLB1
transmembrane protein with metallophosphoesterase domain
galactosidase beta 1
chr22_+_17563485 0.79 ENST00000327451.11
SLC25A18
solute carrier family 25 member 18
chr21_-_44711555 0.79 ENST00000323084.9
TSPEAR
thrombospondin type laminin G domain and EAR repeats
chr1_+_12166978 0.78 ENST00000376259.7
ENST00000536782.2
TNFRSF1B
TNF receptor superfamily member 1B
chr6_-_79947541 0.77 ENST00000369816.5
ELOVL4
ELOVL fatty acid elongase 4
chr15_-_51338575 0.77 ENST00000557858.5
ENST00000558328.5
ENST00000396402.6
ENST00000396404.8
ENST00000561075.5
ENST00000405011.6
ENST00000559980.5
ENST00000453807.6
CYP19A1
cytochrome P450 family 19 subfamily A member 1
chr22_+_50170720 0.76 ENST00000159647.9
ENST00000395842.3
PANX2
pannexin 2
chr12_+_88142290 0.76 ENST00000549011.5
ENST00000551088.1
ENST00000266712.11
TMTC3
transmembrane O-mannosyltransferase targeting cadherins 3
chr4_+_83536097 0.76 ENST00000395226.6
ENST00000264409.5
GPAT3
glycerol-3-phosphate acyltransferase 3
chr5_+_148826600 0.76 ENST00000305988.6
ADRB2
adrenoceptor beta 2
chr7_-_106661148 0.76 ENST00000523505.3
CCDC71L
coiled-coil domain containing 71 like
chr3_-_122514876 0.75 ENST00000493510.1
ENST00000476916.5
ENST00000344337.11
ENST00000465882.5
KPNA1
karyopherin subunit alpha 1
chr7_+_107580215 0.74 ENST00000465919.5
ENST00000005259.9
ENST00000445771.6
ENST00000479917.5
ENST00000421217.5
ENST00000457837.5
BCAP29
B cell receptor associated protein 29
chr8_-_124372686 0.73 ENST00000297632.8
TMEM65
transmembrane protein 65
chr6_-_31139063 0.73 ENST00000259845.5
PSORS1C2
psoriasis susceptibility 1 candidate 2
chr5_+_150778733 0.73 ENST00000526627.2
SMIM3
small integral membrane protein 3
chr2_+_233251571 0.73 ENST00000347464.9
ENST00000444735.5
ENST00000373525.9
ENST00000392017.9
ENST00000419681.5
ATG16L1
autophagy related 16 like 1
chr1_-_229342489 0.71 ENST00000366687.5
CCSAP
centriole, cilia and spindle associated protein
chr19_+_38319807 0.70 ENST00000263372.5
KCNK6
potassium two pore domain channel subfamily K member 6
chr2_+_112482133 0.70 ENST00000233336.7
TTL
tubulin tyrosine ligase
chr5_+_172834225 0.69 ENST00000393784.8
ERGIC1
endoplasmic reticulum-golgi intermediate compartment 1
chr6_-_99349647 0.69 ENST00000389677.6
FAXC
failed axon connections homolog, metaxin like GST domain containing
chr8_+_24914942 0.68 ENST00000433454.3
NEFM
neurofilament medium
chr2_-_36966503 0.68 ENST00000263918.9
STRN
striatin
chr14_+_74881887 0.68 ENST00000334220.9
ENST00000626051.1
ENST00000554806.5
DLST
dihydrolipoamide S-succinyltransferase
chr4_+_15002443 0.68 ENST00000538197.7
CPEB2
cytoplasmic polyadenylation element binding protein 2
chr10_+_18659382 0.68 ENST00000377275.4
ARL5B
ADP ribosylation factor like GTPase 5B
chr16_-_88941198 0.67 ENST00000327483.9
ENST00000564416.1
CBFA2T3
CBFA2/RUNX1 partner transcriptional co-repressor 3
chr8_+_69466617 0.67 ENST00000525061.5
ENST00000260128.8
ENST00000458141.6
SULF1
sulfatase 1
chr10_+_99659430 0.67 ENST00000370489.5
ENTPD7
ectonucleoside triphosphate diphosphohydrolase 7
chr7_+_108569832 0.67 ENST00000249356.4
DNAJB9
DnaJ heat shock protein family (Hsp40) member B9
chr7_+_16646131 0.66 ENST00000415365.5
ENST00000433922.6
ENST00000630952.2
ENST00000258761.8
ENST00000405202.5
BZW2
basic leucine zipper and W2 domains 2
chrX_-_54357993 0.65 ENST00000375169.7
ENST00000354646.6
WNK3
WNK lysine deficient protein kinase 3
chr19_-_51020019 0.65 ENST00000309958.7
KLK10
kallikrein related peptidase 10
chr8_-_47738153 0.65 ENST00000408965.4
CEBPD
CCAAT enhancer binding protein delta
chr15_+_82986198 0.64 ENST00000304191.4
RAMAC
RNA guanine-7 methyltransferase activating subunit
chr3_-_69386079 0.63 ENST00000398540.8
FRMD4B
FERM domain containing 4B
chrX_-_15335407 0.63 ENST00000635543.1
ENST00000542278.6
ENST00000482148.6
ENST00000333590.6
ENST00000637296.1
ENST00000634582.1
ENST00000634640.1
PIGA
phosphatidylinositol glycan anchor biosynthesis class A
chr2_+_30231524 0.62 ENST00000395323.9
ENST00000406087.5
ENST00000404397.5
LBH
LBH regulator of WNT signaling pathway
chr22_+_50185894 0.61 ENST00000380909.9
ENST00000303434.8
TRABD
TraB domain containing
chr19_-_43596123 0.61 ENST00000422989.6
ENST00000598324.1
IRGQ
immunity related GTPase Q
chr13_+_51584435 0.60 ENST00000612477.1
ENST00000298125.7
WDFY2
WD repeat and FYVE domain containing 2
chr12_-_95217373 0.60 ENST00000549499.1
ENST00000546711.5
ENST00000343958.9
FGD6
FYVE, RhoGEF and PH domain containing 6
chr16_-_2858154 0.60 ENST00000571228.1
ENST00000161006.8
PRSS22
serine protease 22
chr1_-_179229671 0.59 ENST00000502732.6
ENST00000392043.4
ABL2
ABL proto-oncogene 2, non-receptor tyrosine kinase
chr15_-_82806054 0.59 ENST00000541889.1
ENST00000334574.12
ENST00000561368.1
FSD2
fibronectin type III and SPRY domain containing 2
chr14_-_70809494 0.59 ENST00000381250.8
ENST00000554752.7
ENST00000555993.6
MAP3K9
mitogen-activated protein kinase kinase kinase 9
chr19_+_1450113 0.59 ENST00000590469.6
ENST00000590877.5
ENST00000233607.6
APC2
APC regulator of WNT signaling pathway 2
chr9_+_100427123 0.58 ENST00000395067.7
MSANTD3
Myb/SANT DNA binding domain containing 3
chr12_-_42238203 0.58 ENST00000327791.8
ENST00000534854.7
YAF2
YY1 associated factor 2
chr22_-_45240859 0.57 ENST00000336156.10
KIAA0930
KIAA0930
chr6_+_4889992 0.57 ENST00000343762.5
CDYL
chromodomain Y like
chr11_-_78341876 0.57 ENST00000340149.6
GAB2
GRB2 associated binding protein 2
chr21_+_29298890 0.56 ENST00000286800.8
BACH1
BTB domain and CNC homolog 1
chr15_+_22786610 0.56 ENST00000337435.9
NIPA1
NIPA magnesium transporter 1
chr1_-_84506565 0.56 ENST00000370641.3
ENST00000370645.9
GNG5
G protein subunit gamma 5
chr13_+_39038292 0.56 ENST00000470258.5
NHLRC3
NHL repeat containing 3
chr6_+_43427535 0.55 ENST00000372530.9
ABCC10
ATP binding cassette subfamily C member 10
chr14_+_52552830 0.55 ENST00000321662.11
GPR137C
G protein-coupled receptor 137C
chr3_-_57693045 0.55 ENST00000311128.10
DENND6A
DENN domain containing 6A
chr19_+_1753499 0.55 ENST00000382349.5
ONECUT3
one cut homeobox 3
chr1_-_208244375 0.55 ENST00000367033.4
PLXNA2
plexin A2
chr1_+_150149819 0.54 ENST00000369124.5
PLEKHO1
pleckstrin homology domain containing O1
chr11_+_117327829 0.54 ENST00000533153.5
ENST00000278935.8
ENST00000525416.5
CEP164
centrosomal protein 164
chr5_-_37371061 0.53 ENST00000513532.1
ENST00000231498.8
NUP155
nucleoporin 155
chr11_+_112074287 0.53 ENST00000532163.5
ENST00000280352.13
ENST00000393047.8
ENST00000526879.5
ENST00000525785.5
NKAPD1
NKAP domain containing 1
chr1_+_153259684 0.53 ENST00000368742.4
LORICRIN
loricrin cornified envelope precursor protein
chr2_+_152718604 0.52 ENST00000326446.10
ARL6IP6
ADP ribosylation factor like GTPase 6 interacting protein 6
chrX_+_153642473 0.52 ENST00000370167.8
DUSP9
dual specificity phosphatase 9
chr7_+_38977904 0.52 ENST00000518318.7
ENST00000403058.6
POU6F2
POU class 6 homeobox 2
chr7_-_92833896 0.51 ENST00000265734.8
CDK6
cyclin dependent kinase 6
chr1_-_165356703 0.51 ENST00000342310.7
LMX1A
LIM homeobox transcription factor 1 alpha
chr11_+_65333834 0.50 ENST00000528416.6
ENST00000415073.6
ENST00000252268.8
DPF2
double PHD fingers 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 5.6 GO:0090402 oncogene-induced cell senescence(GO:0090402)
1.0 5.2 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.9 2.7 GO:0010752 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of cGMP-mediated signaling(GO:0010752)
0.9 3.6 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.8 2.4 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.8 2.3 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.6 1.8 GO:1990654 regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
0.6 1.8 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) regulation of calcium-independent cell-cell adhesion(GO:0051040) corticotropin hormone secreting cell differentiation(GO:0060128)
0.5 2.7 GO:1903238 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609) regulation of voltage-gated chloride channel activity(GO:1902941) positive regulation of voltage-gated chloride channel activity(GO:1902943) positive regulation of leukocyte tethering or rolling(GO:1903238)
0.5 1.6 GO:0030185 nitric oxide transport(GO:0030185)
0.5 1.5 GO:0033241 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.5 1.4 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.5 1.4 GO:0044691 tooth eruption(GO:0044691)
0.4 3.0 GO:0051541 elastin metabolic process(GO:0051541)
0.4 1.8 GO:1904925 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.4 1.1 GO:0032681 negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017)
0.3 2.4 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.3 1.0 GO:0014028 notochord formation(GO:0014028)
0.3 0.3 GO:1903525 regulation of membrane tubulation(GO:1903525) negative regulation of membrane tubulation(GO:1903526)
0.3 1.3 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.3 1.9 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.3 0.9 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.3 0.9 GO:2000591 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) metanephric mesangial cell differentiation(GO:0072209) metanephric glomerular mesangial cell differentiation(GO:0072254) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.3 1.1 GO:0002384 hepatic immune response(GO:0002384)
0.3 3.5 GO:0015693 magnesium ion transport(GO:0015693)
0.3 2.4 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.3 1.3 GO:0045204 MAPK export from nucleus(GO:0045204)
0.3 2.0 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.2 1.5 GO:0022614 membrane to membrane docking(GO:0022614)
0.2 2.1 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.2 3.5 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.2 1.3 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
0.2 0.4 GO:1901204 regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204) negative regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901205)
0.2 1.3 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.2 1.0 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.2 0.8 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.2 1.1 GO:0007386 compartment pattern specification(GO:0007386)
0.2 0.8 GO:2000481 positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
0.2 0.6 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.2 2.7 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.2 3.2 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.2 0.9 GO:1902612 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.2 0.5 GO:0048867 stem cell fate determination(GO:0048867)
0.2 0.7 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.2 1.4 GO:0016926 protein desumoylation(GO:0016926)
0.2 3.4 GO:0060019 radial glial cell differentiation(GO:0060019)
0.2 1.5 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.2 0.5 GO:0021793 chemorepulsion of branchiomotor axon(GO:0021793)
0.2 1.6 GO:0051013 microtubule severing(GO:0051013)
0.2 0.8 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.2 3.5 GO:0071481 cellular response to X-ray(GO:0071481)
0.2 2.4 GO:0032119 sequestering of zinc ion(GO:0032119)
0.2 0.6 GO:2000035 regulation of stem cell division(GO:2000035)
0.2 0.5 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.1 0.3 GO:0002351 serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554)
0.1 1.4 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.7 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.1 4.3 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.1 0.7 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.1 0.9 GO:0002176 male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)
0.1 0.6 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.1 0.7 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.7 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.1 1.9 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.1 1.3 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.1 1.0 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.1 0.9 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 0.4 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.1 1.6 GO:0022417 protein maturation by protein folding(GO:0022417)
0.1 0.4 GO:0001927 exocyst assembly(GO:0001927)
0.1 0.8 GO:0051414 response to cortisol(GO:0051414)
0.1 0.2 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1 1.1 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 1.8 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.1 0.5 GO:0043137 DNA replication, removal of RNA primer(GO:0043137) mitochondrial DNA repair(GO:0043504) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.1 0.3 GO:0070295 renal water absorption(GO:0070295)
0.1 0.3 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.1 2.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 0.3 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.4 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.1 0.3 GO:0035498 carnosine metabolic process(GO:0035498)
0.1 0.5 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016)
0.1 0.3 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.1 0.2 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
0.1 0.5 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.1 0.4 GO:0016240 autophagosome docking(GO:0016240)
0.1 0.7 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 0.2 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.1 1.2 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.8 GO:0071474 cellular hyperosmotic response(GO:0071474)
0.1 0.4 GO:0032252 secretory granule localization(GO:0032252)
0.1 0.3 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.8 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.6 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.7 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.1 0.5 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 0.6 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.1 0.3 GO:0046778 modification by virus of host mRNA processing(GO:0046778)
0.1 0.9 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.3 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.1 0.2 GO:0046337 phosphatidylethanolamine metabolic process(GO:0046337)
0.1 0.5 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.1 0.7 GO:1902019 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.1 0.5 GO:0043697 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.1 1.6 GO:0051290 protein heterotetramerization(GO:0051290)
0.1 0.8 GO:0034214 protein hexamerization(GO:0034214)
0.1 1.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.1 0.6 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 0.9 GO:0070141 response to UV-A(GO:0070141)
0.1 0.9 GO:0016081 synaptic vesicle docking(GO:0016081)
0.1 1.9 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.1 0.2 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.1 0.9 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.1 2.8 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
0.1 0.2 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.1 0.3 GO:1904073 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.1 0.6 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.1 0.5 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.1 0.1 GO:0001878 response to yeast(GO:0001878)
0.1 0.3 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.1 0.8 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.1 0.3 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.1 2.0 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.4 GO:1903912 negative regulation of PERK-mediated unfolded protein response(GO:1903898) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.0 0.5 GO:0051451 myoblast migration(GO:0051451)
0.0 0.3 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.4 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.5 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.3 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.4 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.2 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 2.2 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.6 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.4 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.4 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
0.0 0.4 GO:0034378 chylomicron assembly(GO:0034378)
0.0 3.5 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.6 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.0 0.8 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.3 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.6 GO:0010225 response to UV-C(GO:0010225)
0.0 0.8 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.4 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.9 GO:0043097 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.1 GO:0071486 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473) retinal cell apoptotic process(GO:1990009)
0.0 0.3 GO:0042048 olfactory behavior(GO:0042048)
0.0 0.1 GO:0034147 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
0.0 0.0 GO:0060978 angiogenesis involved in coronary vascular morphogenesis(GO:0060978)
0.0 0.4 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.0 0.1 GO:1901382 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.0 0.3 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.3 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.0 0.3 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.6 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.3 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.3 GO:0070170 regulation of tooth mineralization(GO:0070170)
0.0 1.8 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.7 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 0.3 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
0.0 0.1 GO:0021612 facial nerve structural organization(GO:0021612)
0.0 3.1 GO:0042035 regulation of cytokine biosynthetic process(GO:0042035)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.8 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.8 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 1.4 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.7 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 2.7 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.6 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.9 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.1 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.0 0.9 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.0 0.9 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0 0.3 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 1.3 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.1 GO:0035627 ceramide transport(GO:0035627)
0.0 0.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0097466 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.0 0.1 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.0 0.6 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.7 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.5 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0 0.4 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 1.5 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 1.0 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.3 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.1 GO:0043000 Golgi to plasma membrane CFTR protein transport(GO:0043000)
0.0 0.9 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.6 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 1.6 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.5 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.3 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.3 GO:0097264 self proteolysis(GO:0097264)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532) sulfate transmembrane transport(GO:1902358)
0.0 0.2 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.3 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.2 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955)
0.0 0.6 GO:0051353 positive regulation of oxidoreductase activity(GO:0051353)
0.0 0.2 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.2 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.0 1.2 GO:0006970 response to osmotic stress(GO:0006970)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882) embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0 0.1 GO:1901679 nucleotide transmembrane transport(GO:1901679)
0.0 1.0 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.2 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.0 0.7 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.8 7.0 GO:0005587 collagen type IV trimer(GO:0005587)
0.8 2.3 GO:0005588 collagen type V trimer(GO:0005588)
0.6 5.6 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.6 3.5 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.5 1.6 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.4 1.9 GO:0070557 PCNA-p21 complex(GO:0070557)
0.3 1.6 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.3 1.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.3 2.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.2 2.7 GO:0005577 fibrinogen complex(GO:0005577)
0.2 0.9 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.2 1.8 GO:0032133 chromosome passenger complex(GO:0032133)
0.2 2.1 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 1.5 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.2 0.5 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.2 0.5 GO:0044611 nuclear pore inner ring(GO:0044611)
0.2 0.5 GO:0005760 gamma DNA polymerase complex(GO:0005760)
0.1 1.2 GO:0071986 Ragulator complex(GO:0071986)
0.1 0.7 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.1 2.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 1.3 GO:0051286 cell tip(GO:0051286)
0.1 0.2 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.8 GO:0005683 U7 snRNP(GO:0005683)
0.1 1.2 GO:0016600 flotillin complex(GO:0016600)
0.1 0.9 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.1 0.4 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.4 GO:1990425 ryanodine receptor complex(GO:1990425)
0.1 0.3 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 1.0 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 1.5 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 0.3 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 0.4 GO:0031417 NatC complex(GO:0031417)
0.1 0.7 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 1.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.7 GO:0005883 neurofilament(GO:0005883)
0.1 0.4 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.1 0.3 GO:0097422 tubular endosome(GO:0097422)
0.1 0.4 GO:0043196 varicosity(GO:0043196)
0.1 0.6 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.3 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.3 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.4 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.5 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 0.3 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.6 GO:0016342 catenin complex(GO:0016342)
0.0 0.5 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.5 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 3.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0044308 axonal spine(GO:0044308)
0.0 2.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.6 GO:0097228 sperm principal piece(GO:0097228)
0.0 4.2 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.4 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.1 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
0.0 3.1 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.2 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.8 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.0 0.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 2.4 GO:0005795 Golgi stack(GO:0005795)
0.0 0.7 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.7 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.5 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.6 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 1.8 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 1.7 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 2.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 0.4 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 8.2 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 2.5 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.8 GO:0005921 gap junction(GO:0005921)
0.0 1.0 GO:0002102 podosome(GO:0002102)
0.0 2.0 GO:0005604 basement membrane(GO:0005604)
0.0 0.4 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 1.0 GO:0016235 aggresome(GO:0016235)
0.0 0.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 1.4 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 4.7 GO:0045121 membrane raft(GO:0045121)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 3.3 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.8 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.2 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.9 2.7 GO:0070052 collagen V binding(GO:0070052)
0.9 2.7 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.9 4.3 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.8 3.2 GO:0035501 MH1 domain binding(GO:0035501)
0.8 2.4 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.7 2.1 GO:0055100 adiponectin binding(GO:0055100)
0.7 2.8 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.7 2.7 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.5 1.5 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.4 2.4 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.4 1.1 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981) ciliary neurotrophic factor binding(GO:0070119)
0.4 1.9 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.3 2.4 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.3 1.4 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.3 1.6 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.3 1.6 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.3 0.8 GO:0071209 U7 snRNA binding(GO:0071209)
0.3 1.6 GO:0031708 endothelin B receptor binding(GO:0031708)
0.2 0.9 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.2 1.6 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.2 1.4 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.2 0.9 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.2 3.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 2.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 1.8 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 1.0 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.2 1.6 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.2 0.8 GO:0016936 galactoside binding(GO:0016936)
0.2 3.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.2 0.8 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.1 2.1 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.5 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 0.4 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.1 1.9 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.5 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 2.8 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.6 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.3 GO:0000247 C-8 sterol isomerase activity(GO:0000247)
0.1 0.3 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.1 0.7 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 0.8 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.1 0.3 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.1 1.3 GO:0030911 TPR domain binding(GO:0030911)
0.1 0.4 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 0.5 GO:0016890 site-specific endodeoxyribonuclease activity, specific for altered base(GO:0016890)
0.1 0.5 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 4.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 10.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 1.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 2.2 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.3 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 0.5 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 1.2 GO:1901612 cardiolipin binding(GO:1901612)
0.1 3.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 1.6 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.1 0.8 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.4 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.3 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 0.7 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 1.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.6 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.5 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.3 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.1 0.4 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.1 0.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.3 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.7 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 2.4 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.3 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.6 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.5 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0 0.4 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.3 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.0 0.3 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 1.0 GO:0005112 Notch binding(GO:0005112)
0.0 2.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.7 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.7 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 1.2 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.9 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 2.5 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 5.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.4 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.3 GO:0046975 histone methyltransferase activity (H4-K20 specific)(GO:0042799) histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.7 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.3 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.3 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 2.1 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.2 GO:0089720 caspase binding(GO:0089720)
0.0 0.3 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.8 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 1.0 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.7 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.9 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.4 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 1.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.0 0.2 GO:0043184 C-X3-C chemokine binding(GO:0019960) vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 1.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.8 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.2 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.1 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.2 GO:0004630 phospholipase D activity(GO:0004630)
0.0 1.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.1 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.2 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.3 GO:0034452 dynactin binding(GO:0034452)
0.0 0.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.7 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 2.2 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.0 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
0.0 1.4 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.5 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.1 GO:0035197 siRNA binding(GO:0035197)
0.0 0.3 GO:0055103 ligase regulator activity(GO:0055103)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 3.0 GO:0051015 actin filament binding(GO:0051015)
0.0 5.2 GO:0045296 cadherin binding(GO:0045296)
0.0 2.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.7 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2 11.4 NABA COLLAGENS Genes encoding collagen proteins
0.1 3.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 10.6 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 3.8 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 1.9 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.6 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.0 PID ARF 3PATHWAY Arf1 pathway
0.0 2.1 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 1.2 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 3.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.5 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 1.0 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 8.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.3 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.1 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.8 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.2 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.9 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.3 PID FOXO PATHWAY FoxO family signaling
0.0 5.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.2 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.6 PID E2F PATHWAY E2F transcription factor network
0.0 1.4 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.1 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.6 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 2.1 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.5 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.5 PID ATR PATHWAY ATR signaling pathway
0.0 0.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.2 PID NETRIN PATHWAY Netrin-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.3 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.2 3.5 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.2 5.0 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 11.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 2.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 2.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 6.7 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 2.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 3.0 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 2.6 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 0.9 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 1.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 0.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.7 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.7 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 1.2 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.5 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.9 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.9 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.7 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 3.0 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 3.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 5.2 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.0 1.2 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.9 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.3 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.6 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.8 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.7 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.4 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.3 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.6 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.3 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.3 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.6 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 1.0 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase