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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for GCM2

Z-value: 0.58

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Transcription factors associated with GCM2

Gene Symbol Gene ID Gene Info
ENSG00000124827.7 GCM2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GCM2hg38_v1_chr6_-_10882037_108820480.086.7e-01Click!

Activity profile of GCM2 motif

Sorted Z-values of GCM2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GCM2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_-_205455954 1.10 ENST00000495594.2
ENST00000629624.2
LEM domain containing 1
bladder cancer associated transcript 1
chr22_+_31093358 0.99 ENST00000404574.5
smoothelin
chr1_+_150549734 0.85 ENST00000674043.1
ENST00000674058.1
ADAMTS like 4
chr1_+_150549384 0.83 ENST00000369041.9
ENST00000271643.9
ADAMTS like 4
chr11_-_58578096 0.70 ENST00000528954.5
ENST00000528489.1
leupaxin
chr1_+_43358968 0.62 ENST00000310955.11
cell division cycle 20
chr1_+_43358998 0.61 ENST00000372462.1
cell division cycle 20
chr16_+_22814154 0.58 ENST00000261374.4
heparan sulfate-glucosamine 3-sulfotransferase 2
chr1_+_20552515 0.56 ENST00000332947.6
family with sequence similarity 43 member B
chr5_+_83471736 0.53 ENST00000265077.8
versican
chr5_+_83471668 0.49 ENST00000342785.8
ENST00000343200.9
versican
chr15_-_41332487 0.47 ENST00000560640.1
ENST00000220514.8
Opa interacting protein 5
chr18_-_14132423 0.47 ENST00000589498.5
ENST00000590202.3
zinc finger protein 519
chr17_-_74361860 0.47 ENST00000375366.4
BTB domain containing 17
chr17_-_44830242 0.45 ENST00000592524.6
gap junction protein gamma 1
chr19_-_45785659 0.45 ENST00000537879.1
ENST00000596586.5
ENST00000595946.1
DM1 locus, WD repeat containing
novel protein
chr19_+_46602050 0.45 ENST00000599839.5
ENST00000596362.1
calmodulin 3
chr5_+_83471764 0.44 ENST00000512590.6
ENST00000513960.5
ENST00000513984.5
versican
chr15_+_41332862 0.44 ENST00000450592.6
ENST00000414849.6
ENST00000559596.6
ENST00000560747.5
ENST00000560177.5
nucleolar and spindle associated protein 1
chr22_+_37051787 0.41 ENST00000456470.1
potassium channel tetramerization domain containing 17
chr8_+_31640358 0.41 ENST00000523534.5
neuregulin 1
chr19_+_54502799 0.41 ENST00000301202.7
leukocyte associated immunoglobulin like receptor 2
chr9_+_125748175 0.40 ENST00000491787.7
ENST00000447726.6
PBX homeobox 3
chr3_-_86991135 0.40 ENST00000398399.7
vestigial like family member 3
chr19_-_51368979 0.40 ENST00000601435.1
ENST00000291715.5
claudin domain containing 2
chr19_+_54502867 0.39 ENST00000351841.2
leukocyte associated immunoglobulin like receptor 2
chr3_-_48556785 0.39 ENST00000232375.8
ENST00000383734.6
ENST00000416568.5
ENST00000412035.5
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr19_+_35292125 0.38 ENST00000600291.5
ENST00000361922.8
myelin associated glycoprotein
chr14_+_104579757 0.38 ENST00000331952.6
ENST00000557649.6
chromosome 14 open reading frame 180
chr19_+_35292145 0.38 ENST00000595791.5
ENST00000597035.5
ENST00000537831.2
ENST00000392213.8
myelin associated glycoprotein
chr7_-_105679089 0.37 ENST00000477775.5
ataxin 7 like 1
chr17_-_44830774 0.36 ENST00000590758.3
ENST00000591424.5
gap junction protein gamma 1
chr16_+_71358713 0.36 ENST00000349553.9
ENST00000302628.9
ENST00000562305.5
calbindin 2
chr13_+_31846713 0.35 ENST00000645780.1
FRY microtubule binding protein
chr11_-_6320494 0.35 ENST00000303927.4
ENST00000530979.1
caveolae associated protein 3
chr3_+_155079663 0.35 ENST00000460393.6
membrane metalloendopeptidase
chr11_-_10693740 0.35 ENST00000423302.7
inositol 1,4,5-triphosphate receptor associated 1
chr7_+_2631978 0.34 ENST00000258796.12
tweety family member 3
chr1_-_243850070 0.34 ENST00000366539.6
ENST00000672578.1
AKT serine/threonine kinase 3
chr3_+_155079847 0.33 ENST00000615825.2
membrane metalloendopeptidase
chr13_-_44161257 0.33 ENST00000400419.2
small integral membrane protein 2
chr5_+_83471925 0.33 ENST00000502527.2
versican
chr1_+_27872536 0.33 ENST00000328928.11
ENST00000373921.8
ENST00000373925.5
ENST00000373927.7
ENST00000427466.1
ENST00000442118.5
thymocyte selection associated family member 2
chr7_-_94656197 0.33 ENST00000643903.1
ENST00000644122.1
ENST00000447873.6
ENST00000644816.1
ENST00000644375.1
sarcoglycan epsilon
chr7_-_94655993 0.33 ENST00000647110.1
ENST00000647048.1
ENST00000643020.1
ENST00000644682.1
ENST00000646119.1
ENST00000646265.1
ENST00000645445.1
ENST00000647334.1
ENST00000645262.1
ENST00000428696.7
ENST00000647096.1
ENST00000642394.1
ENST00000645725.1
ENST00000647351.1
ENST00000646943.1
ENST00000648936.2
ENST00000642707.1
ENST00000645109.1
ENST00000646489.1
ENST00000642933.1
ENST00000643128.1
ENST00000445866.7
ENST00000645101.1
ENST00000644116.1
ENST00000642441.1
ENST00000646879.1
ENST00000647018.1
sarcoglycan epsilon
chr16_+_2009870 0.32 ENST00000567649.1
neuropeptide W
chr9_+_70043840 0.32 ENST00000377182.5
MAM domain containing 2
chr1_-_16431371 0.32 ENST00000612240.1
spermatogenesis associated 21
chr3_+_155079911 0.32 ENST00000675418.2
membrane metalloendopeptidase
chr6_-_110179702 0.32 ENST00000392587.6
WASP family member 1
chr1_+_44800367 0.31 ENST00000372201.5
polo like kinase 3
chr17_-_58488375 0.31 ENST00000323777.8
heat shock transcription factor 5
chr6_-_110179623 0.30 ENST00000265601.7
ENST00000447287.5
ENST00000392589.6
ENST00000444391.5
WASP family member 1
chr7_-_94656160 0.30 ENST00000644609.1
ENST00000643272.1
ENST00000646137.1
ENST00000646098.1
ENST00000643193.1
ENST00000437425.7
ENST00000644551.1
ENST00000415788.3
sarcoglycan epsilon
chr2_+_94871419 0.30 ENST00000295201.5
tektin 4
chr12_+_14973020 0.30 ENST00000266395.3
phosphodiesterase 6H
chr7_+_2632029 0.29 ENST00000407643.5
tweety family member 3
chr4_-_152779710 0.29 ENST00000304337.3
tigger transposable element derived 4
chr5_+_123512214 0.29 ENST00000511130.6
ENST00000512718.7
casein kinase 1 gamma 3
chr1_-_31798755 0.29 ENST00000452755.6
SPOC domain containing 1
chr11_-_10693504 0.29 ENST00000529547.1
ENST00000558540.5
inositol 1,4,5-triphosphate receptor associated 1
chr2_-_219543793 0.28 ENST00000243776.11
chondroitin polymerizing factor
chr3_+_155080088 0.28 ENST00000462745.5
membrane metalloendopeptidase
chr19_+_39296399 0.28 ENST00000333625.3
interferon lambda 1
chr9_-_96655280 0.27 ENST00000446045.1
ENST00000375234.8
peroxiredoxin like 2C
chr19_+_35856885 0.27 ENST00000347900.10
ENST00000360202.10
kirre like nephrin family adhesion molecule 2
chr20_+_43514492 0.27 ENST00000373135.8
ENST00000373134.5
L3MBTL histone methyl-lysine binding protein 1
chrX_-_154805516 0.26 ENST00000413259.7
membrane palmitoylated protein 1
chr17_-_16353409 0.26 ENST00000299736.5
centromere protein V
chr22_+_37051731 0.26 ENST00000610767.4
ENST00000402077.7
ENST00000403888.7
potassium channel tetramerization domain containing 17
chr5_-_173328407 0.26 ENST00000265087.9
stanniocalcin 2
chr4_-_76421121 0.26 ENST00000682701.1
coiled-coil domain containing 158
chr12_-_52618559 0.25 ENST00000305748.7
keratin 73
chr15_+_88621290 0.25 ENST00000332810.4
ENST00000559528.1
apoptosis enhancing nuclease
chr19_+_40717091 0.25 ENST00000263370.3
inositol-trisphosphate 3-kinase C
chr5_-_54985579 0.24 ENST00000381405.5
ENST00000381403.4
endothelial cell specific molecule 1
chr8_-_86069662 0.24 ENST00000276616.3
protein serine kinase H2
chr17_-_78903193 0.24 ENST00000322630.3
ENST00000586713.5
CEP295 N-terminal like
chr3_+_50674896 0.24 ENST00000266037.10
dedicator of cytokinesis 3
chr20_+_43457885 0.24 ENST00000668808.1
ENST00000670741.1
ENST00000662078.1
ENST00000244020.5
ENST00000657241.1
serine and arginine rich splicing factor 6
novel protein
chr16_-_10182394 0.23 ENST00000330684.4
glutamate ionotropic receptor NMDA type subunit 2A
chr22_+_19718390 0.23 ENST00000383045.7
ENST00000438754.6
septin 5
chr5_-_150290093 0.23 ENST00000672479.1
calcium/calmodulin dependent protein kinase II alpha
chr12_+_55966821 0.23 ENST00000553376.5
ENST00000440311.6
ENST00000266970.9
ENST00000354056.4
cyclin dependent kinase 2
chr1_-_243850216 0.23 ENST00000673466.1
AKT serine/threonine kinase 3
chr18_+_3449620 0.23 ENST00000405385.7
TGFB induced factor homeobox 1
chr14_+_64504574 0.23 ENST00000358738.3
zinc finger and BTB domain containing 1
chr4_+_153466324 0.22 ENST00000409663.7
ENST00000409959.8
transmembrane 131 like
chr11_-_124320197 0.22 ENST00000624618.2
olfactory receptor family 8 subfamily D member 2
chr12_-_16606102 0.22 ENST00000537304.6
LIM domain only 3
chr17_-_42979993 0.21 ENST00000409103.5
ENST00000360221.8
ENST00000454303.1
ENST00000591916.7
ENST00000451885.3
PTGES3L-AARSD1 readthrough
prostaglandin E synthase 3 like
chr12_+_56996151 0.21 ENST00000556850.1
G protein-coupled receptor 182
chr4_-_52038260 0.21 ENST00000381431.10
sarcoglycan beta
chr12_-_48004467 0.21 ENST00000380518.8
collagen type II alpha 1 chain
chr12_-_16605939 0.21 ENST00000541295.5
ENST00000535535.5
LIM domain only 3
chr22_+_19723525 0.21 ENST00000366425.4
glycoprotein Ib platelet subunit beta
chr2_+_219544002 0.20 ENST00000421791.1
ENST00000373883.4
ENST00000451952.1
transmembrane protein 198
chr19_+_639895 0.20 ENST00000586042.6
ENST00000215530.6
fibroblast growth factor 22
chr15_+_74615808 0.20 ENST00000395066.9
ENST00000568139.6
ENST00000563297.5
ENST00000568488.6
CDC like kinase 3
chr17_+_7455571 0.20 ENST00000575379.1
cholinergic receptor nicotinic beta 1 subunit
chr14_-_105168753 0.20 ENST00000331782.8
ENST00000347004.2
jagged canonical Notch ligand 2
chr5_-_73448769 0.20 ENST00000615637.3
forkhead box D1
chrX_-_154805386 0.20 ENST00000393531.5
ENST00000369534.8
ENST00000453245.5
ENST00000428488.1
ENST00000369531.1
membrane palmitoylated protein 1
chr11_-_83682414 0.20 ENST00000404783.7
discs large MAGUK scaffold protein 2
chr11_+_117232625 0.20 ENST00000534428.5
ENST00000300650.9
ring finger protein 214
chr20_+_45791930 0.19 ENST00000372622.8
deoxynucleotidyltransferase terminal interacting protein 1
chr19_+_45039040 0.19 ENST00000221455.8
ENST00000391953.8
ENST00000588936.5
CLK4 associating serine/arginine rich protein
chr19_-_40716869 0.19 ENST00000677018.1
ENST00000324464.8
ENST00000594720.6
ENST00000677496.1
coenzyme Q8B
chr1_+_155209213 0.19 ENST00000609421.1
metaxin 1
chr3_+_130931893 0.19 ENST00000504612.5
ATPase secretory pathway Ca2+ transporting 1
chr22_-_39244969 0.19 ENST00000331163.11
platelet derived growth factor subunit B
chr9_-_137423153 0.19 ENST00000479452.5
ENST00000340951.9
ENST00000465160.2
exonuclease 3'-5' domain containing 3
chr19_-_19515542 0.19 ENST00000585580.4
testis specific serine kinase 6
chr19_+_18612848 0.19 ENST00000262817.8
transmembrane protein 59 like
chr7_-_44325421 0.19 ENST00000395747.6
ENST00000347193.8
ENST00000346990.8
ENST00000258682.10
ENST00000353625.8
ENST00000421607.1
ENST00000424197.5
calcium/calmodulin dependent protein kinase II beta
chr19_+_35000275 0.18 ENST00000317991.10
ENST00000680623.1
GRAM domain containing 1A
chr15_-_29968864 0.18 ENST00000356107.11
tight junction protein 1
chr2_+_232406836 0.18 ENST00000295453.8
alkaline phosphatase, germ cell
chr10_-_48524236 0.18 ENST00000374170.5
Rho GTPase activating protein 22
chr6_-_40587314 0.18 ENST00000338305.7
leucine rich repeat and fibronectin type III domain containing 2
chr9_+_132162045 0.18 ENST00000393229.4
netrin G2
chr18_+_57435366 0.18 ENST00000491143.3
one cut homeobox 2
chr1_+_213987929 0.17 ENST00000498508.6
ENST00000366958.9
prospero homeobox 1
chr11_-_12009082 0.17 ENST00000396505.7
dickkopf WNT signaling pathway inhibitor 3
chr20_+_45791978 0.17 ENST00000449078.5
ENST00000456939.5
deoxynucleotidyltransferase terminal interacting protein 1
chr14_+_41608344 0.17 ENST00000554120.5
leucine rich repeat and fibronectin type III domain containing 5
chr17_-_29005913 0.17 ENST00000442608.7
ENST00000317338.17
ENST00000335960.10
seizure related 6 homolog
chr13_-_98577094 0.17 ENST00000539966.6
serine/threonine kinase 24
chr12_-_48004496 0.17 ENST00000337299.7
collagen type II alpha 1 chain
chr9_+_136712531 0.16 ENST00000371692.9
divergent protein kinase domain 1B
chr19_+_45039509 0.16 ENST00000544944.6
CLK4 associating serine/arginine rich protein
chrX_-_71068384 0.16 ENST00000276105.3
ENST00000622259.4
sorting nexin 12
chr14_+_92513766 0.16 ENST00000216487.12
ENST00000620541.4
ENST00000557762.1
Ras and Rab interactor 3
chrX_-_21658324 0.16 ENST00000379499.3
kelch like family member 34
chr9_-_130939205 0.16 ENST00000372338.9
fibrinogen C domain containing 1
chr19_-_10315987 0.15 ENST00000393708.3
ENST00000494368.5
ferredoxin 2
chr11_-_117232033 0.15 ENST00000524507.6
ENST00000320934.8
ENST00000532301.5
ENST00000676339.1
ENST00000540028.5
proprotein convertase subtilisin/kexin type 7
chr12_-_103495953 0.15 ENST00000552578.1
ENST00000548048.5
ENST00000548883.5
ENST00000378113.7
chromosome 12 open reading frame 42
chr17_+_6070361 0.15 ENST00000317744.10
WSC domain containing 1
chr2_+_238158926 0.15 ENST00000546354.6
erythroferrone
chr11_-_12008584 0.15 ENST00000534511.5
ENST00000683431.1
dickkopf WNT signaling pathway inhibitor 3
chr9_-_130939068 0.15 ENST00000448616.5
ENST00000451466.1
fibrinogen C domain containing 1
chrX_+_47078434 0.15 ENST00000397180.6
regucalcin
chrX_+_47078330 0.15 ENST00000457380.5
regucalcin
chrX_+_43654888 0.15 ENST00000542639.5
monoamine oxidase A
chr14_-_59630582 0.15 ENST00000395090.5
reticulon 1
chr12_-_213338 0.15 ENST00000424061.6
solute carrier family 6 member 12
chr8_-_92103217 0.15 ENST00000615601.4
ENST00000523629.5
RUNX1 partner transcriptional co-repressor 1
chr1_-_26360050 0.14 ENST00000475866.3
crystallin beta-gamma domain containing 2
chr11_-_10693570 0.14 ENST00000527509.7
inositol 1,4,5-triphosphate receptor associated 1
chr6_+_46793379 0.14 ENST00000230588.9
ENST00000611727.2
meprin A subunit alpha
chr3_+_186666003 0.14 ENST00000232003.5
histidine rich glycoprotein
chr14_-_64504570 0.14 ENST00000394715.1
zinc finger and BTB domain containing 25
chr14_-_49586325 0.14 ENST00000557519.1
ENST00000396020.7
ENST00000554075.2
ENST00000245458.11
ribosomal protein S29
chr13_-_98577131 0.14 ENST00000397517.6
serine/threonine kinase 24
chr14_-_59630806 0.14 ENST00000342503.8
reticulon 1
chr6_-_138218491 0.14 ENST00000527246.3
prostate and breast cancer overexpressed 1
chr2_+_178194460 0.14 ENST00000392505.6
ENST00000359685.7
ENST00000357080.8
ENST00000190611.9
ENST00000409045.7
oxysterol binding protein like 6
chr2_-_72825982 0.14 ENST00000634650.1
ENST00000272427.11
ENST00000410104.1
exocyst complex component 6B
chr6_-_6007511 0.14 ENST00000616243.1
neuritin 1
chr8_+_133113483 0.14 ENST00000521107.1
thyroglobulin
chr17_+_7435416 0.13 ENST00000323206.2
ENST00000396568.1
transmembrane protein 102
chr11_+_4094775 0.13 ENST00000300738.10
ribonucleotide reductase catalytic subunit M1
chrX_+_47078380 0.13 ENST00000352078.8
regucalcin
chr7_+_5879827 0.13 ENST00000416608.5
oncomodulin
chr3_+_35639589 0.13 ENST00000428373.5
cAMP regulated phosphoprotein 21
chr19_+_7348930 0.13 ENST00000668164.2
Rho/Rac guanine nucleotide exchange factor 18
chr11_+_5488685 0.13 ENST00000322641.5
olfactory receptor family 52 subfamily D member 1
chr15_+_78340344 0.13 ENST00000299529.7
cellular retinoic acid binding protein 1
chr1_+_109910986 0.12 ENST00000369801.1
colony stimulating factor 1
chr1_-_204190324 0.12 ENST00000638118.1
renin
chr5_-_177311882 0.12 ENST00000513169.1
ENST00000423571.6
ENST00000502529.1
ENST00000427908.6
MAX dimerization protein 3
chr11_-_61429934 0.11 ENST00000541963.5
ENST00000477890.6
ENST00000439958.8
cleavage and polyadenylation specific factor 7
chr17_+_1742836 0.11 ENST00000324015.7
ENST00000450523.6
ENST00000453723.5
ENST00000453066.6
ENST00000382061.5
serpin family F member 2
chr19_-_14560170 0.11 ENST00000679223.1
DnaJ heat shock protein family (Hsp40) member B1
chr2_+_219434825 0.11 ENST00000312358.12
striated muscle enriched protein kinase
chr3_+_42685535 0.11 ENST00000287777.5
kelch like family member 40
chr19_-_10315737 0.11 ENST00000492239.5
ferredoxin 2
chr13_-_46897021 0.11 ENST00000542664.4
ENST00000543956.5
5-hydroxytryptamine receptor 2A
chr17_-_27793716 0.11 ENST00000646938.1
nitric oxide synthase 2
chr9_+_100578071 0.11 ENST00000307584.6
caveolae associated protein 4
chr19_-_14475307 0.11 ENST00000292513.4
prostaglandin E receptor 1
chr16_+_55479188 0.11 ENST00000219070.9
matrix metallopeptidase 2
chr6_+_31666056 0.10 ENST00000375882.7
ENST00000375880.6
casein kinase 2 beta
novel protein
chr11_-_83682385 0.10 ENST00000426717.6
discs large MAGUK scaffold protein 2
chr17_-_7219813 0.10 ENST00000399510.8
ENST00000648172.8
discs large MAGUK scaffold protein 4
chr1_-_118988301 0.10 ENST00000369429.5
T-box transcription factor 15
chr11_+_64234569 0.10 ENST00000309422.7
ENST00000426086.3
vascular endothelial growth factor B
chr1_+_2050387 0.10 ENST00000378567.8
protein kinase C zeta
chr6_+_130018565 0.10 ENST00000361794.7
ENST00000526087.5
ENST00000533560.5
L3MBTL histone methyl-lysine binding protein 3
chr22_-_29061831 0.09 ENST00000216071.5
chromosome 22 open reading frame 31
chr21_+_37366744 0.09 ENST00000647188.2
dual specificity tyrosine phosphorylation regulated kinase 1A
chr20_+_43514426 0.09 ENST00000422861.3
L3MBTL histone methyl-lysine binding protein 1
chr17_-_42681840 0.09 ENST00000332438.4
C-C motif chemokine receptor 10
chr1_+_203626775 0.09 ENST00000367218.7
ATPase plasma membrane Ca2+ transporting 4
chr11_-_61430008 0.09 ENST00000394888.8
cleavage and polyadenylation specific factor 7
chr21_+_37367097 0.09 ENST00000644942.1
dual specificity tyrosine phosphorylation regulated kinase 1A
chr22_+_50600783 0.09 ENST00000329492.6
mitogen-activated protein kinase 8 interacting protein 2
chr1_-_159923717 0.09 ENST00000368096.5
transgelin 2
chr1_+_960549 0.09 ENST00000338591.8
ENST00000622660.1
kelch like family member 17

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.1 1.3 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 0.4 GO:0043465 fermentation(GO:0006113) regulation of fermentation(GO:0043465)
0.1 0.5 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.1 0.4 GO:1903627 regulation of calcium-dependent ATPase activity(GO:1903610) negative regulation of calcium-dependent ATPase activity(GO:1903611) regulation of dUTP diphosphatase activity(GO:1903627) positive regulation of dUTP diphosphatase activity(GO:1903629) negative regulation of aminoacyl-tRNA ligase activity(GO:1903631) regulation of leucine-tRNA ligase activity(GO:1903633) negative regulation of leucine-tRNA ligase activity(GO:1903634)
0.1 0.3 GO:2000777 positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.1 1.7 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 0.4 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.1 0.7 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.1 0.3 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.1 0.2 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.1 0.1 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.1 0.6 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.4 GO:0007386 compartment pattern specification(GO:0007386)
0.1 1.8 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 0.4 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.3 GO:1902613 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.1 0.8 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.1 0.2 GO:1903974 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.1 0.2 GO:0035793 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) metanephric mesangial cell differentiation(GO:0072209) metanephric glomerular mesangial cell differentiation(GO:0072254) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.1 0.4 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1 0.2 GO:0043049 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.1 0.2 GO:2000283 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.0 0.2 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 1.2 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.2 GO:0033058 directional locomotion(GO:0033058)
0.0 0.1 GO:0034653 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.0 0.2 GO:0072076 nephrogenic mesenchyme development(GO:0072076)
0.0 0.1 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.0 0.2 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.0 0.3 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.0 0.2 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.4 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.6 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.2 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 0.1 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.0 0.1 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.4 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.2 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0 0.1 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.4 GO:0060174 limb bud formation(GO:0060174)
0.0 0.2 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 0.7 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 0.4 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.1 GO:0044860 protein localization to plasma membrane raft(GO:0044860)
0.0 1.0 GO:0046710 GDP metabolic process(GO:0046710)
0.0 0.2 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.0 0.1 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.3 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.1 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.1 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.0 0.2 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.1 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0 0.0 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0 0.3 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.2 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.1 GO:0035509 negative regulation of myosin-light-chain-phosphatase activity(GO:0035509) negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.2 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.3 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.1 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.5 GO:0061641 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.0 GO:0002184 cytoplasmic translational termination(GO:0002184)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.3 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.1 0.2 GO:0000805 X chromosome(GO:0000805) cyclin E2-CDK2 complex(GO:0097135)
0.1 1.7 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.8 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.7 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 1.3 GO:0005921 gap junction(GO:0005921)
0.0 0.4 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 1.2 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.3 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.4 GO:0010369 chromocenter(GO:0010369)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 2.0 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 1.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.7 GO:0002102 podosome(GO:0002102)
0.0 0.0 GO:0018444 translation release factor complex(GO:0018444)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.1 1.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 0.4 GO:0032093 SAM domain binding(GO:0032093)
0.1 0.4 GO:0004341 gluconolactonase activity(GO:0004341)
0.1 0.6 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.3 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.4 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 0.8 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.4 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.2 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.0 1.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.7 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.6 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.3 GO:0008061 chitin binding(GO:0008061)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 1.0 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.2 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.8 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.7 ST GAQ PATHWAY G alpha q Pathway
0.0 0.9 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.3 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.5 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 1.2 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.8 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.2 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.5 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.3 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.8 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.4 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors