Project

Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

Navigation
Downloads

Results for GLIS2

Z-value: 0.99

Motif logo

Transcription factors associated with GLIS2

Gene Symbol Gene ID Gene Info
ENSG00000126603.9 GLIS2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GLIS2hg38_v1_chr16_+_4316052_4316075-0.561.2e-03Click!

Activity profile of GLIS2 motif

Sorted Z-values of GLIS2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GLIS2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image
Promoter Score Transcript Gene Gene Info
chr19_+_35154914 5.79 ENST00000423817.7
FXYD domain containing ion transport regulator 5
chr19_+_35154715 5.68 ENST00000392218.6
ENST00000543307.5
ENST00000392219.7
ENST00000541435.6
ENST00000590686.5
ENST00000342879.7
ENST00000588699.5
FXYD domain containing ion transport regulator 5
chr6_-_2903300 3.48 ENST00000380698.5
serpin family B member 9
chr7_-_73719629 3.15 ENST00000395155.3
ENST00000395154.7
ENST00000395156.7
ENST00000222812.8
syntaxin 1A
chr1_-_186680411 3.14 ENST00000367468.10
prostaglandin-endoperoxide synthase 2
chr6_-_39322688 2.98 ENST00000437525.3
potassium two pore domain channel subfamily K member 16
chr2_+_233195433 2.54 ENST00000417661.1
inositol polyphosphate-5-phosphatase D
chr1_-_28193873 2.25 ENST00000305392.3
ENST00000539896.1
platelet activating factor receptor
chr1_-_153375591 2.18 ENST00000368737.5
S100 calcium binding protein A12
chr2_+_37344594 2.13 ENST00000404976.5
ENST00000338415.8
glutaminyl-peptide cyclotransferase
chr1_-_6490564 2.12 ENST00000377725.5
ENST00000340850.10
pleckstrin homology and RhoGEF domain containing G5
chr19_+_44905785 2.04 ENST00000446996.5
ENST00000252486.9
ENST00000434152.5
apolipoprotein E
chr19_+_48325323 1.98 ENST00000596315.5
epithelial membrane protein 3
chr22_+_22922594 1.96 ENST00000390331.3
immunoglobulin lambda constant 7
chrX_-_154374623 1.95 ENST00000369850.10
filamin A
chr2_+_24049673 1.94 ENST00000380991.8
FKBP prolyl isomerase 1B
chr12_-_52848986 1.93 ENST00000304620.5
keratin 78
chr2_+_24049705 1.86 ENST00000380986.9
ENST00000452109.1
FKBP prolyl isomerase 1B
chr19_+_1407731 1.85 ENST00000592453.2
DAZ associated protein 1
chr19_+_11089446 1.74 ENST00000557933.5
ENST00000455727.6
ENST00000535915.5
ENST00000545707.5
ENST00000558518.6
ENST00000558013.5
low density lipoprotein receptor
chr19_+_48321454 1.70 ENST00000599704.5
epithelial membrane protein 3
chr13_+_110307276 1.70 ENST00000360467.7
ENST00000650540.1
collagen type IV alpha 2 chain
chr19_+_53869384 1.67 ENST00000391769.2
myeloid associated differentiation marker
chr19_+_44914833 1.67 ENST00000589078.1
ENST00000586638.5
apolipoprotein C1
chr14_+_94174284 1.67 ENST00000304338.8
protein phosphatase 4 regulatory subunit 4
chr5_-_177409535 1.64 ENST00000253496.4
coagulation factor XII
chr9_+_113594118 1.62 ENST00000620489.1
regulator of G protein signaling 3
chrX_-_154371210 1.60 ENST00000369856.8
ENST00000422373.6
ENST00000360319.9
filamin A
chr17_+_43398984 1.59 ENST00000320033.5
ADP ribosylation factor like GTPase 4D
chr8_+_27325516 1.56 ENST00000346049.10
ENST00000420218.3
protein tyrosine kinase 2 beta
chr13_-_20192928 1.53 ENST00000382848.5
gap junction protein beta 2
chr11_-_64878612 1.53 ENST00000320631.8
EH domain containing 1
chr19_+_44914588 1.50 ENST00000592535.6
apolipoprotein C1
chr5_-_132777215 1.46 ENST00000458488.2
septin 8
chr19_+_44914247 1.45 ENST00000588750.5
ENST00000588802.5
apolipoprotein C1
chr1_-_155978427 1.42 ENST00000313667.8
Rho/Rac guanine nucleotide exchange factor 2
chr3_-_48595267 1.42 ENST00000328333.12
ENST00000681320.1
collagen type VII alpha 1 chain
chr21_+_33403391 1.42 ENST00000290219.11
ENST00000381995.5
interferon gamma receptor 2
chr19_+_44914702 1.42 ENST00000592885.5
ENST00000589781.1
apolipoprotein C1
chr1_-_231040218 1.34 ENST00000366654.5
family with sequence similarity 89 member A
chr19_+_17747698 1.30 ENST00000594202.5
ENST00000252771.11
FCH and mu domain containing endocytic adaptor 1
chr16_-_90008988 1.30 ENST00000568662.2
dysbindin domain containing 1
chr11_+_844067 1.29 ENST00000397406.5
ENST00000409543.6
ENST00000525201.5
tetraspanin 4
chr22_+_22644475 1.29 ENST00000618722.4
ENST00000652219.1
ENST00000480559.6
ENST00000448514.2
ENST00000652249.1
ENST00000651213.1
gamma-glutamyltransferase light chain 2
chr19_+_2249317 1.29 ENST00000221496.5
anti-Mullerian hormone
chr9_+_136952256 1.29 ENST00000371633.8
lipocalin 12
chr1_+_34782259 1.26 ENST00000373362.3
gap junction protein beta 3
chr16_+_30183595 1.25 ENST00000219150.10
ENST00000570045.5
ENST00000565497.5
ENST00000570244.5
coronin 1A
chr12_+_57460127 1.24 ENST00000532291.5
ENST00000543426.5
ENST00000546141.5
GLI family zinc finger 1
chr6_-_39322540 1.24 ENST00000425054.6
ENST00000373227.8
ENST00000373229.9
potassium two pore domain channel subfamily K member 16
chr13_-_23433676 1.24 ENST00000682547.1
ENST00000455470.6
ENST00000382292.9
sacsin molecular chaperone
chr19_+_17747737 1.23 ENST00000600676.5
ENST00000600209.5
ENST00000596309.5
ENST00000598539.5
ENST00000597474.5
ENST00000593385.5
ENST00000598067.5
ENST00000593833.5
FCH and mu domain containing endocytic adaptor 1
chr1_-_156705742 1.22 ENST00000368221.1
cellular retinoic acid binding protein 2
chr19_+_41755520 1.20 ENST00000199764.7
CEA cell adhesion molecule 6
chr21_-_30497160 1.17 ENST00000334058.3
keratin associated protein 19-4
chr20_+_46008900 1.16 ENST00000372330.3
matrix metallopeptidase 9
chr19_-_42427379 1.14 ENST00000244289.9
lipase E, hormone sensitive type
chr5_+_169583636 1.14 ENST00000506574.5
ENST00000515224.5
ENST00000629457.2
ENST00000508247.5
ENST00000265295.9
ENST00000513941.5
spindle apparatus coiled-coil protein 1
chr20_-_23988779 1.12 ENST00000335694.4
gamma-glutamyltransferase light chain 1
chrX_-_30308333 1.12 ENST00000378963.1
nuclear receptor subfamily 0 group B member 1
chr3_-_48088824 1.12 ENST00000439356.2
ENST00000395734.7
ENST00000426837.6
microtubule associated protein 4
chr19_-_41353904 1.11 ENST00000221930.6
transforming growth factor beta 1
chr1_-_156705764 1.09 ENST00000621784.4
ENST00000368220.1
cellular retinoic acid binding protein 2
chr6_-_39322968 1.08 ENST00000507712.5
potassium two pore domain channel subfamily K member 16
chr9_+_136952896 1.08 ENST00000371632.7
lipocalin 12
chr1_-_151008365 1.07 ENST00000361936.9
ENST00000361738.11
MINDY lysine 48 deubiquitinase 1
chr1_+_2019379 1.06 ENST00000638771.1
ENST00000640949.1
ENST00000640030.1
gamma-aminobutyric acid type A receptor subunit delta
chr22_-_30289607 1.06 ENST00000404953.7
cytosolic arginine sensor for mTORC1 subunit 1
chr20_+_37346128 1.04 ENST00000373578.7
SRC proto-oncogene, non-receptor tyrosine kinase
chr16_+_57245229 1.04 ENST00000219204.8
ADP ribosylation factor like GTPase 2 binding protein
chr11_+_111245725 1.04 ENST00000280325.7
chromosome 11 open reading frame 53
chr2_+_219627622 1.01 ENST00000358055.8
solute carrier family 4 member 3
chr17_+_6444441 1.01 ENST00000250056.12
ENST00000571373.5
ENST00000570337.6
ENST00000572595.6
ENST00000572447.6
ENST00000576056.5
PICALM interacting mitotic regulator
chr22_-_27801712 1.00 ENST00000302326.5
MN1 proto-oncogene, transcriptional regulator
chr3_+_111859284 1.00 ENST00000498699.5
pleckstrin homology like domain family B member 2
chr2_+_219627650 1.00 ENST00000317151.7
solute carrier family 4 member 3
chr21_+_33403466 0.99 ENST00000405436.5
interferon gamma receptor 2
chr1_-_156705575 0.98 ENST00000368222.8
cellular retinoic acid binding protein 2
chr5_-_1523900 0.96 ENST00000283415.4
lysophosphatidylcholine acyltransferase 1
chr16_-_28506826 0.96 ENST00000356897.1
interleukin 27
chr16_+_70646536 0.94 ENST00000288098.6
interleukin 34
chr11_-_1622093 0.94 ENST00000616115.1
ENST00000399682.1
keratin associated protein 5-4
chr10_-_133336862 0.92 ENST00000368555.3
ENST00000252939.9
ENST00000368558.1
calcyon neuron specific vesicular protein
chr3_+_111859180 0.92 ENST00000412622.5
ENST00000431670.7
pleckstrin homology like domain family B member 2
chr19_-_37906646 0.89 ENST00000303868.5
WD repeat domain 87
chr11_+_450255 0.89 ENST00000308020.6
phosphatidylserine synthase 2
chr19_+_3506355 0.85 ENST00000652521.1
fizzy and cell division cycle 20 related 1
chr11_-_627173 0.85 ENST00000176195.4
secretin
chr9_+_100427123 0.83 ENST00000395067.7
Myb/SANT DNA binding domain containing 3
chr20_+_64084995 0.83 ENST00000349451.3
opioid related nociceptin receptor 1
chr13_+_42272134 0.81 ENST00000025301.4
A-kinase anchoring protein 11
chr2_-_89010515 0.81 ENST00000493819.1
immunoglobulin kappa variable 1-9
chr19_-_37906588 0.80 ENST00000447313.7
WD repeat domain 87
chr9_+_100427254 0.80 ENST00000374885.5
Myb/SANT DNA binding domain containing 3
chr1_+_35079374 0.80 ENST00000359858.9
ENST00000373330.1
zinc finger MYM-type containing 1
chr9_+_123356189 0.80 ENST00000373631.8
crumbs cell polarity complex component 2
chr3_+_111859796 0.79 ENST00000393925.7
pleckstrin homology like domain family B member 2
chr22_-_39244969 0.78 ENST00000331163.11
platelet derived growth factor subunit B
chr6_-_150069066 0.77 ENST00000438272.2
ENST00000367339.7
UL16 binding protein 3
chr19_-_45902594 0.77 ENST00000322217.6
Myb related transcription factor, partner of profilin
chr10_+_104254915 0.77 ENST00000445155.5
glutathione S-transferase omega 1
chr22_+_29073112 0.75 ENST00000327813.9
ENST00000407188.5
kringle containing transmembrane protein 1
chr16_+_57245336 0.75 ENST00000562023.5
ENST00000563234.1
ADP ribosylation factor like GTPase 2 binding protein
chr1_-_155978144 0.74 ENST00000313695.11
ENST00000497907.5
Rho/Rac guanine nucleotide exchange factor 2
chr10_+_104254867 0.73 ENST00000369713.10
glutathione S-transferase omega 1
chr5_-_141680822 0.69 ENST00000504448.1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr20_+_54208072 0.69 ENST00000371419.7
prefoldin subunit 4
chr17_-_42979993 0.69 ENST00000409103.5
ENST00000360221.8
ENST00000454303.1
ENST00000591916.7
ENST00000451885.3
PTGES3L-AARSD1 readthrough
prostaglandin E synthase 3 like
chr16_+_27066919 0.67 ENST00000505035.3
chromosome 16 open reading frame 82
chr12_+_7155867 0.67 ENST00000535313.2
ENST00000331148.5
calsyntenin 3
chr11_-_72642407 0.67 ENST00000376450.7
phosphodiesterase 2A
chr19_-_36152427 0.66 ENST00000589154.1
ENST00000292907.8
cytochrome c oxidase subunit 7A1
chr20_-_31845593 0.65 ENST00000375978.5
forkhead box S1
chr11_-_72642450 0.65 ENST00000444035.6
ENST00000544570.5
phosphodiesterase 2A
chr19_-_4517600 0.65 ENST00000301286.4
perilipin 4
chr2_-_135876382 0.65 ENST00000264156.3
minichromosome maintenance complex component 6
chr19_-_40750302 0.65 ENST00000598485.6
ENST00000378313.7
ENST00000470681.5
chromosome 19 open reading frame 54
chr16_+_69424634 0.64 ENST00000515314.6
ENST00000561792.6
ENST00000568237.1
cytochrome b5 type B
chr19_+_1407653 0.63 ENST00000587079.5
DAZ associated protein 1
chr1_+_150982268 0.62 ENST00000368947.9
annexin A9
chr12_-_110689105 0.62 ENST00000242607.13
hydrogen voltage gated channel 1
chr9_-_35112379 0.62 ENST00000488109.6
family with sequence similarity 214 member B
chr14_-_106211453 0.62 ENST00000390606.3
immunoglobulin heavy variable 3-20
chr1_-_201115372 0.62 ENST00000458416.2
achaete-scute family bHLH transcription factor 5
chr19_+_3185911 0.61 ENST00000246117.9
ENST00000588428.5
nicalin
chr8_-_86069662 0.61 ENST00000276616.3
protein serine kinase H2
chr21_+_46001300 0.61 ENST00000612273.2
ENST00000682634.1
collagen type VI alpha 1 chain
chr19_+_55339867 0.61 ENST00000255613.8
lysine methyltransferase 5C
chr17_+_42017020 0.61 ENST00000307641.9
NFKB inhibitor interacting Ras like 2
chr3_+_38165484 0.60 ENST00000446845.5
ENST00000311806.8
oxidative stress responsive kinase 1
chr3_-_43621897 0.60 ENST00000444344.5
ENST00000456438.5
ENST00000350459.8
ENST00000396091.7
ENST00000451430.6
ENST00000428472.5
ENST00000292246.8
ENST00000414522.6
anoctamin 10
chr8_+_38386433 0.60 ENST00000297720.9
ENST00000524874.5
ENST00000379957.9
ENST00000523983.6
leucine zipper and EF-hand containing transmembrane protein 2
chr11_+_68903849 0.59 ENST00000675615.1
ENST00000255078.8
immunoglobulin mu DNA binding protein 2
chr5_-_132777404 0.58 ENST00000296873.11
septin 8
chr12_-_57547224 0.58 ENST00000678322.1
dynactin subunit 2
chr17_+_7307579 0.57 ENST00000572815.5
eukaryotic translation initiation factor 5A
chr19_+_45079195 0.57 ENST00000591607.1
ENST00000591747.5
ENST00000270257.9
ENST00000391951.2
ENST00000587566.5
gem nuclear organelle associated protein 7
microtubule affinity regulating kinase 4
chr7_+_101154981 0.57 ENST00000646560.1
adaptor related protein complex 1 subunit sigma 1
chr1_+_2019324 0.56 ENST00000638411.1
ENST00000378585.7
ENST00000640067.1
gamma-aminobutyric acid type A receptor subunit delta
chr1_+_65147514 0.56 ENST00000545314.5
adenylate kinase 4
chr20_+_56533246 0.55 ENST00000371325.1
family with sequence similarity 209 member B
chr12_-_57547121 0.55 ENST00000550954.5
ENST00000434715.7
ENST00000678505.1
ENST00000543672.6
ENST00000546670.5
ENST00000548249.6
dynactin subunit 2
chr17_+_18108706 0.55 ENST00000615845.4
myosin XVA
chr19_-_40285277 0.55 ENST00000579047.5
ENST00000392038.7
AKT serine/threonine kinase 2
chr7_-_727242 0.55 ENST00000537384.6
ENST00000417852.5
protein kinase cAMP-dependent type I regulatory subunit beta
chr14_+_99684283 0.54 ENST00000261835.8
cytochrome P450 family 46 subfamily A member 1
chr22_+_50674879 0.54 ENST00000262795.6
SH3 and multiple ankyrin repeat domains 3
chr11_-_2423012 0.54 ENST00000533881.5
ENST00000533060.5
ENST00000528453.1
ENST00000155858.10
transient receptor potential cation channel subfamily M member 5
chr17_+_18108747 0.53 ENST00000647165.2
myosin XVA
chr19_+_1275508 0.52 ENST00000409293.6
family with sequence similarity 174 member C
chr7_-_727611 0.52 ENST00000403562.5
protein kinase cAMP-dependent type I regulatory subunit beta
chr5_+_150671588 0.52 ENST00000523553.1
myozenin 3
chr1_+_160081529 0.51 ENST00000368088.4
potassium inwardly rectifying channel subfamily J member 9
chr9_+_124869126 0.51 ENST00000259477.6
actin related protein 2/3 complex subunit 5 like
chr13_+_46553157 0.51 ENST00000311191.10
ENST00000389797.8
ENST00000389798.7
leucine rich repeats and calponin homology domain containing 1
chr20_-_31723491 0.50 ENST00000676582.1
ENST00000422920.2
BCL2 like 1
chr7_-_712940 0.50 ENST00000544935.5
ENST00000430040.5
ENST00000456696.2
ENST00000406797.5
protein kinase cAMP-dependent type I regulatory subunit beta
chr14_-_105601728 0.49 ENST00000641420.1
ENST00000390541.2
immunoglobulin heavy constant epsilon
chr19_+_39413528 0.49 ENST00000438123.5
ENST00000409797.6
ENST00000451354.6
pleckstrin homology and RhoGEF domain containing G2
chr19_+_53909263 0.49 ENST00000391767.6
calcium voltage-gated channel auxiliary subunit gamma 7
chr17_-_5234801 0.48 ENST00000571800.5
ENST00000574081.6
ENST00000399600.8
ENST00000574297.1
SLP adaptor and CSK interacting membrane protein
chr5_-_132777866 0.48 ENST00000448933.5
septin 8
chr10_+_96304392 0.48 ENST00000630152.1
DNA nucleotidylexotransferase
chr5_-_132777371 0.48 ENST00000620483.4
septin 8
chr10_+_96304425 0.47 ENST00000371174.5
DNA nucleotidylexotransferase
chr8_+_1823918 0.47 ENST00000349830.8
Rho guanine nucleotide exchange factor 10
chr16_+_3020359 0.47 ENST00000341627.5
ENST00000326577.9
ENST00000575124.1
ENST00000575836.1
TNF receptor superfamily member 12A
chr19_+_14529580 0.46 ENST00000215567.10
trans-2,3-enoyl-CoA reductase
chr7_-_712437 0.46 ENST00000360274.8
protein kinase cAMP-dependent type I regulatory subunit beta
chr3_-_28348924 0.45 ENST00000414162.5
ENST00000420543.6
5-azacytidine induced 2
chr1_-_23800402 0.45 ENST00000374497.7
ENST00000425913.5
UDP-galactose-4-epimerase
chr19_+_3506251 0.45 ENST00000441788.7
fizzy and cell division cycle 20 related 1
chr3_-_177197210 0.45 ENST00000431421.5
ENST00000422066.5
ENST00000413084.5
ENST00000673974.1
ENST00000422442.6
TBL1X receptor 1
chr9_-_35958154 0.45 ENST00000341959.2
olfactory receptor family 2 subfamily S member 2
chr12_-_54584302 0.45 ENST00000553113.5
protein phosphatase 1 regulatory inhibitor subunit 1A
chr12_-_48957365 0.44 ENST00000398092.4
ENST00000539611.1
novel protein
ADP ribosylation factor 3
chr19_-_3772211 0.44 ENST00000555978.5
ENST00000555633.3
retina and anterior neural fold homeobox 2
chr15_-_34343112 0.44 ENST00000557912.1
ENST00000328848.6
NOP10 ribonucleoprotein
chr19_+_13764502 0.43 ENST00000040663.8
ENST00000319545.12
methylthioribose-1-phosphate isomerase 1
chr14_-_56810380 0.43 ENST00000672125.1
ENST00000673481.1
orthodenticle homeobox 2
chr19_-_40285395 0.43 ENST00000424901.5
ENST00000578123.5
AKT serine/threonine kinase 2
chr19_-_38812936 0.42 ENST00000307751.9
ENST00000594209.1
galectin 4
chr6_-_70303070 0.42 ENST00000370496.3
ENST00000357250.11
collagen type IX alpha 1 chain
chr15_+_90935277 0.41 ENST00000418476.2
unc-45 myosin chaperone A
chr17_-_41836193 0.41 ENST00000435506.7
ENST00000415460.5
5'-nucleotidase, cytosolic IIIB
chr2_-_196926717 0.41 ENST00000409475.5
ENST00000374738.3
post-GPI attachment to proteins inositol deacylase 1
chr19_+_10871516 0.41 ENST00000327064.9
ENST00000588947.5
coactivator associated arginine methyltransferase 1
chr19_+_44751251 0.40 ENST00000444487.1
BCL3 transcription coactivator
chr19_+_55605639 0.40 ENST00000568956.2
zinc finger protein 865
chr2_-_15561305 0.40 ENST00000281513.10
NBAS subunit of NRZ tethering complex
chr17_+_82458174 0.40 ENST00000579198.5
ENST00000390006.8
ENST00000580296.5
nuclear prelamin A recognition factor
chr1_-_201154418 0.40 ENST00000435310.5
ENST00000485839.6
transmembrane protein 9
chr1_-_114757971 0.39 ENST00000261443.9
ENST00000534699.5
ENST00000339438.10
ENST00000358528.9
ENST00000529046.5
ENST00000525970.5
ENST00000369530.5
ENST00000530886.5
ENST00000610726.4
cold shock domain containing E1
chr14_-_77498808 0.38 ENST00000342219.9
ENST00000493585.5
ENST00000554801.2
isthmin 2
chr5_-_170389634 0.38 ENST00000521859.1
potassium calcium-activated channel subfamily M regulatory beta subunit 1
chr2_+_9843426 0.38 ENST00000625239.2
ENST00000263663.10
TATA-box binding protein associated factor, RNA polymerase I subunit B
chr3_-_11846772 0.38 ENST00000455809.5
ENST00000444133.6
ENST00000273037.9
ENST00000630288.1
TAM41 mitochondrial translocator assembly and maintenance homolog
chr15_-_79090760 0.38 ENST00000419573.7
ENST00000558480.7
Ras protein specific guanine nucleotide releasing factor 1
chr12_-_109833373 0.38 ENST00000261740.7
transient receptor potential cation channel subfamily V member 4
chrX_+_46573757 0.38 ENST00000276055.4
carbohydrate sulfotransferase 7

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 11.5 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
1.5 6.0 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
1.2 3.6 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
1.2 3.5 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
1.1 3.4 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.7 2.0 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.6 2.5 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.6 3.1 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.6 1.7 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.5 2.1 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.5 1.6 GO:2000538 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.5 1.5 GO:0014810 positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014810)
0.5 2.3 GO:0009608 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609) regulation of voltage-gated chloride channel activity(GO:1902941) positive regulation of voltage-gated chloride channel activity(GO:1902943) positive regulation of leukocyte tethering or rolling(GO:1903238)
0.4 1.7 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072)
0.4 1.7 GO:0010899 regulation of phosphatidylcholine catabolic process(GO:0010899) positive regulation of lysosomal protein catabolic process(GO:1905167)
0.4 2.2 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.4 1.3 GO:0001546 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.4 1.2 GO:0060032 notochord regression(GO:0060032)
0.4 1.6 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of fibrinolysis(GO:0051919)
0.4 3.8 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.4 1.1 GO:1903576 response to L-arginine(GO:1903576)
0.3 1.0 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473) retinal cell apoptotic process(GO:1990009)
0.3 1.5 GO:0044752 response to human chorionic gonadotropin(GO:0044752)
0.3 0.8 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187) regulation of somatostatin secretion(GO:0090273) positive regulation of somatostatin secretion(GO:0090274)
0.3 1.1 GO:0052509 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.3 0.8 GO:0014028 notochord formation(GO:0014028)
0.3 1.3 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.2 3.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.2 2.9 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.2 1.0 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641) cellular response to progesterone stimulus(GO:0071393)
0.2 0.6 GO:0051463 negative regulation of cortisol secretion(GO:0051463)
0.2 1.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.2 1.1 GO:0051012 microtubule sliding(GO:0051012)
0.2 0.6 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.2 0.8 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.2 3.8 GO:0030322 stabilization of membrane potential(GO:0030322)
0.2 0.5 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
0.1 0.6 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 1.2 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.1 3.7 GO:0032060 bleb assembly(GO:0032060)
0.1 1.2 GO:0031339 negative regulation of vesicle fusion(GO:0031339) negative regulation of actin nucleation(GO:0051126)
0.1 0.4 GO:0034970 regulation of growth plate cartilage chondrocyte proliferation(GO:0003420) histone H3-R2 methylation(GO:0034970)
0.1 0.4 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.1 0.4 GO:0001189 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.1 0.4 GO:0007231 osmosensory signaling pathway(GO:0007231)
0.1 1.0 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.1 3.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.9 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 0.4 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.1 2.0 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 1.7 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 0.3 GO:0006097 glyoxylate cycle(GO:0006097)
0.1 0.7 GO:0015798 myo-inositol transport(GO:0015798)
0.1 0.5 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 0.5 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.1 0.7 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 0.2 GO:0072720 response to dithiothreitol(GO:0072720)
0.1 0.4 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 0.4 GO:1903413 cellular response to bile acid(GO:1903413)
0.1 0.6 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.1 1.0 GO:0045625 regulation of T-helper 1 cell differentiation(GO:0045625)
0.1 0.2 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 0.2 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.1 0.6 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.4 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.1 2.5 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 0.1 GO:2000547 regulation of dendritic cell dendrite assembly(GO:2000547)
0.1 0.5 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 0.2 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.1 0.5 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1 0.4 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 1.1 GO:0030238 male sex determination(GO:0030238)
0.1 1.3 GO:0006751 glutathione catabolic process(GO:0006751)
0.1 0.1 GO:0060516 primary prostatic bud elongation(GO:0060516)
0.1 0.3 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.1 1.1 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 0.2 GO:2000612 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.1 1.2 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.1 1.7 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 0.9 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.1 1.8 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.1 1.3 GO:0090344 negative regulation of cell aging(GO:0090344)
0.1 0.2 GO:0000103 sulfate assimilation(GO:0000103)
0.1 2.2 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.1 0.4 GO:0060762 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) regulation of branching involved in mammary gland duct morphogenesis(GO:0060762) germline stem cell asymmetric division(GO:0098728)
0.1 0.2 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.2 GO:1990523 bone regeneration(GO:1990523)
0.0 0.4 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.0 3.3 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.4 GO:0044860 protein localization to plasma membrane raft(GO:0044860)
0.0 0.1 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.0 0.2 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.0 0.3 GO:0002254 kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.0 0.1 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.6 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.3 GO:0051754 female meiosis chromosome segregation(GO:0016321) meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 1.6 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.3 GO:1903236 regulation of leukocyte tethering or rolling(GO:1903236)
0.0 1.4 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.4 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.9 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.1 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.0 0.4 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.0 1.9 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.0 0.4 GO:0060992 response to fungicide(GO:0060992)
0.0 2.2 GO:0002548 monocyte chemotaxis(GO:0002548)
0.0 0.7 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.1 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.1 GO:0051795 positive regulation of catagen(GO:0051795)
0.0 0.4 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 0.4 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.7 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.5 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.4 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.3 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 1.8 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.7 GO:0045577 regulation of B cell differentiation(GO:0045577)
0.0 0.3 GO:0045109 intermediate filament organization(GO:0045109)
0.0 1.1 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.4 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.6 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.4 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.5 GO:0030497 fatty acid elongation(GO:0030497)
0.0 0.1 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 1.4 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.3 GO:0071787 positive regulation of mammary gland epithelial cell proliferation(GO:0033601) endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.0 GO:2000374 regulation of oxygen metabolic process(GO:2000374)
0.0 4.3 GO:0031424 keratinization(GO:0031424)
0.0 1.0 GO:0033198 response to ATP(GO:0033198)
0.0 0.2 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.4 GO:0021924 cell proliferation in external granule layer(GO:0021924) cerebellar granule cell precursor proliferation(GO:0021930) proteasome assembly(GO:0043248)
0.0 0.3 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.3 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686) positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.4 GO:0014029 neural crest formation(GO:0014029)
0.0 0.8 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.7 GO:0032094 response to food(GO:0032094)
0.0 0.8 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 1.3 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.0 2.3 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.4 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.2 GO:0070315 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718) G1 to G0 transition involved in cell differentiation(GO:0070315)
0.0 0.1 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.0 0.2 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.2 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.5 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.6 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.6 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.6 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.2 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.3 GO:0040018 positive regulation of multicellular organism growth(GO:0040018)
0.0 0.1 GO:0070673 response to interleukin-18(GO:0070673)
0.0 0.6 GO:0031648 protein destabilization(GO:0031648)
0.0 0.3 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.3 GO:0051923 sulfation(GO:0051923)
0.0 0.1 GO:0044375 peroxisome membrane biogenesis(GO:0016557) regulation of peroxisome size(GO:0044375)
0.0 0.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.3 GO:0051984 positive regulation of chromosome segregation(GO:0051984)
0.0 0.2 GO:0000042 protein targeting to Golgi(GO:0000042)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.7 3.6 GO:0031523 Myb complex(GO:0031523)
0.6 1.7 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.5 2.0 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.3 1.5 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.2 1.4 GO:0030934 anchoring collagen complex(GO:0030934)
0.2 5.6 GO:0042627 chylomicron(GO:0042627)
0.2 1.7 GO:0005587 collagen type IV trimer(GO:0005587)
0.2 3.1 GO:0045180 basal cortex(GO:0045180)
0.1 0.4 GO:0070939 Dsl1p complex(GO:0070939)
0.1 2.7 GO:0005922 connexon complex(GO:0005922)
0.1 0.3 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 1.2 GO:0032797 SMN complex(GO:0032797)
0.1 1.2 GO:0070852 cell body fiber(GO:0070852)
0.1 0.4 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 2.0 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 1.1 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.7 GO:0016272 prefoldin complex(GO:0016272)
0.1 1.1 GO:0005869 dynactin complex(GO:0005869)
0.1 1.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.2 GO:0018444 translation release factor complex(GO:0018444)
0.1 1.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.6 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.4 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 0.4 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 0.4 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.1 1.1 GO:0061700 GATOR2 complex(GO:0061700)
0.1 3.1 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 3.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 3.2 GO:0002102 podosome(GO:0002102)
0.0 0.6 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 1.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.9 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 1.2 GO:0097546 ciliary base(GO:0097546)
0.0 0.6 GO:0042555 MCM complex(GO:0042555)
0.0 3.5 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 1.6 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 1.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.4 GO:0005638 lamin filament(GO:0005638)
0.0 0.9 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.4 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.6 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.3 GO:0005579 membrane attack complex(GO:0005579)
0.0 2.7 GO:0045095 keratin filament(GO:0045095)
0.0 3.5 GO:0005811 lipid particle(GO:0005811)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.4 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 1.0 GO:0000791 euchromatin(GO:0000791)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 2.3 GO:0005901 caveola(GO:0005901)
0.0 2.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 2.0 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 2.0 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.1 GO:0034448 EGO complex(GO:0034448)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.7 GO:0031904 endosome lumen(GO:0031904)
0.0 1.1 GO:0032420 stereocilium(GO:0032420)
0.0 2.3 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 1.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.2 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.1 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 1.1 GO:0005882 intermediate filament(GO:0005882)
0.0 0.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.8 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.7 8.1 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.7 3.6 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.6 3.1 GO:0050473 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.6 2.4 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.6 2.3 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.4 2.7 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.4 1.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.2 1.5 GO:0045174 glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.2 3.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.2 1.0 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.2 1.1 GO:0043515 kinetochore binding(GO:0043515)
0.2 1.0 GO:0071253 connexin binding(GO:0071253)
0.2 1.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.2 0.8 GO:0001626 nociceptin receptor activity(GO:0001626)
0.2 1.0 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.2 1.1 GO:0070004 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.2 3.8 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.2 2.5 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.2 3.5 GO:0019841 retinol binding(GO:0019841)
0.2 1.3 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.2 1.3 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.2 0.5 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.1 1.6 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 2.4 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.1 10.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.9 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 2.7 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.4 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 0.4 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.1 0.6 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 1.1 GO:0034618 arginine binding(GO:0034618)
0.1 0.5 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.1 0.6 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 1.3 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 2.5 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 1.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 2.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 2.0 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 0.3 GO:0070984 SET domain binding(GO:0070984)
0.1 0.9 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.1 0.3 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450) (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.1 0.9 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 1.8 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.6 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 0.4 GO:0016936 galactoside binding(GO:0016936)
0.1 0.2 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 3.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.5 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.5 GO:0051373 FATZ binding(GO:0051373)
0.1 0.8 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 1.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.6 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 1.6 GO:0070628 proteasome binding(GO:0070628)
0.1 3.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.2 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.1 1.0 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 0.4 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.4 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 2.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 1.7 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.5 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.3 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 0.2 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.1 GO:0052870 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.4 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 1.4 GO:0000217 DNA secondary structure binding(GO:0000217)
0.0 0.2 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.5 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.4 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.8 GO:0051787 misfolded protein binding(GO:0051787)
0.0 1.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.8 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.4 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.4 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.3 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.3 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.2 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.6 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.4 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.6 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.2 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 1.0 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 3.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.2 GO:0030942 signal recognition particle binding(GO:0005047) endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.6 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 1.5 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.3 GO:0004985 opioid receptor activity(GO:0004985)
0.0 3.2 GO:0005179 hormone activity(GO:0005179)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 1.3 GO:0030507 spectrin binding(GO:0030507)
0.0 0.7 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.7 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.3 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.4 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.6 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.0 1.7 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.5 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.4 GO:0005521 lamin binding(GO:0005521)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.0 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.7 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.7 GO:0043022 ribosome binding(GO:0043022)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 3.9 PID S1P S1P1 PATHWAY S1P1 pathway
0.1 4.5 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.1 1.7 NABA COLLAGENS Genes encoding collagen proteins
0.1 1.3 PID ALK2 PATHWAY ALK2 signaling events
0.1 4.7 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 3.6 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 1.8 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.6 PID IL5 PATHWAY IL5-mediated signaling events
0.0 2.4 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.2 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.0 PID IL27 PATHWAY IL27-mediated signaling events
0.0 2.0 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.7 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.3 PID AURORA A PATHWAY Aurora A signaling
0.0 1.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.4 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.7 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.5 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 5.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.5 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 4.7 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.8 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 3.8 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 3.1 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 2.7 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 2.4 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 2.6 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 2.2 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 1.9 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 1.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 1.5 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 2.0 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 4.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 3.3 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 1.0 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.0 0.6 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 1.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.7 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 2.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.5 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.3 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.2 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.7 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.7 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.5 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.2 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.8 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 1.3 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 3.0 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 2.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.8 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.6 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 1.2 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 1.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.4 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 1.3 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.1 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes