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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for GUAAACA

Z-value: 0.90

Motif logo

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miRNA associated with seed GUAAACA

NamemiRBASE accession
hsa-miR-30a-5p
MIMAT0000087
hsa-miR-30b-5p
MIMAT0000420
hsa-miR-30c-5p
MIMAT0000244
hsa-miR-30d-5p
MIMAT0000245
hsa-miR-30e-5p
MIMAT0000692

Activity profile of GUAAACA motif

Sorted Z-values of GUAAACA motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GUAAACA

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr6_+_85449584 1.72 ENST00000369651.7
NT5E
5'-nucleotidase ecto
chr10_+_17229267 1.36 ENST00000224237.9
VIM
vimentin
chr11_-_115504389 1.30 ENST00000545380.5
ENST00000452722.7
ENST00000331581.11
ENST00000537058.5
ENST00000536727.5
ENST00000542447.6
CADM1
cell adhesion molecule 1
chr4_-_138242325 1.21 ENST00000280612.9
SLC7A11
solute carrier family 7 member 11
chr7_+_101127095 1.21 ENST00000223095.5
SERPINE1
serpin family E member 1
chr7_-_41703062 1.14 ENST00000242208.5
INHBA
inhibin subunit beta A
chr8_+_26577843 1.11 ENST00000311151.9
DPYSL2
dihydropyrimidinase like 2
chr6_-_30687200 1.00 ENST00000399199.7
PPP1R18
protein phosphatase 1 regulatory subunit 18
chr2_+_95025700 0.92 ENST00000309988.9
ENST00000353004.7
ENST00000354078.7
ENST00000349807.3
MAL
mal, T cell differentiation protein
chr7_-_84194781 0.92 ENST00000265362.9
SEMA3A
semaphorin 3A
chr7_-_143362687 0.92 ENST00000409578.5
ENST00000443739.7
ENST00000409346.5
FAM131B
family with sequence similarity 131 member B
chr11_-_88175432 0.87 ENST00000531138.1
ENST00000526372.1
ENST00000243662.11
RAB38
RAB38, member RAS oncogene family
chr7_+_87876472 0.78 ENST00000265728.6
DBF4
DBF4 zinc finger
chr5_-_157575767 0.77 ENST00000257527.9
ADAM19
ADAM metallopeptidase domain 19
chr5_+_87268922 0.75 ENST00000456692.6
ENST00000512763.5
ENST00000506290.1
RASA1
RAS p21 protein activator 1
chr13_-_61415508 0.75 ENST00000409204.4
PCDH20
protocadherin 20
chr5_+_172641241 0.74 ENST00000369800.6
ENST00000520919.5
ENST00000522853.5
NEURL1B
neuralized E3 ubiquitin protein ligase 1B
chr6_+_117907226 0.74 ENST00000360388.9
SLC35F1
solute carrier family 35 member F1
chr5_+_14143322 0.73 ENST00000344204.9
TRIO
trio Rho guanine nucleotide exchange factor
chr22_+_32801697 0.72 ENST00000266085.7
TIMP3
TIMP metallopeptidase inhibitor 3
chr1_-_9129085 0.71 ENST00000377411.5
GPR157
G protein-coupled receptor 157
chr15_-_83284645 0.70 ENST00000345382.7
BNC1
basonuclin 1
chr15_-_34336749 0.69 ENST00000397707.6
ENST00000560611.5
SLC12A6
solute carrier family 12 member 6
chr1_+_145095967 0.68 ENST00000400889.3
FAM72D
family with sequence similarity 72 member D
chr17_+_72121012 0.68 ENST00000245479.3
SOX9
SRY-box transcription factor 9
chr1_-_121184292 0.67 ENST00000452190.2
ENST00000619376.4
ENST00000369390.7
FAM72B
family with sequence similarity 72 member B
chr14_-_44961889 0.64 ENST00000579157.1
ENST00000396128.9
ENST00000556500.1
KLHL28
kelch like family member 28
chr2_-_25982471 0.63 ENST00000264712.8
KIF3C
kinesin family member 3C
chr10_+_76318330 0.63 ENST00000496424.2
LRMDA
leucine rich melanocyte differentiation associated
chr8_+_91070196 0.62 ENST00000617869.4
ENST00000615618.1
ENST00000285420.8
ENST00000404789.8
OTUD6B
OTU deubiquitinase 6B
chr7_-_27095972 0.62 ENST00000355633.5
ENST00000643460.2
HOXA1
homeobox A1
chr16_-_30010972 0.62 ENST00000565273.5
ENST00000567332.6
ENST00000350119.9
DOC2A
double C2 domain alpha
chr22_-_37427433 0.61 ENST00000452946.1
ENST00000402918.7
ELFN2
ELFN2
extracellular leucine rich repeat and fibronectin type III domain containing 2
extracellular leucine rich repeat and fibronectin type III domain containing 2
chr20_-_21514046 0.61 ENST00000377142.5
NKX2-2
NK2 homeobox 2
chr9_-_69672341 0.60 ENST00000265381.7
APBA1
amyloid beta precursor protein binding family A member 1
chr1_-_20486197 0.60 ENST00000375078.4
CAMK2N1
calcium/calmodulin dependent protein kinase II inhibitor 1
chr9_+_100473140 0.60 ENST00000374879.5
TMEFF1
transmembrane protein with EGF like and two follistatin like domains 1
chr19_+_926001 0.59 ENST00000263620.8
ARID3A
AT-rich interaction domain 3A
chr5_-_135034212 0.58 ENST00000265340.12
PITX1
paired like homeodomain 1
chr10_-_114404480 0.58 ENST00000419268.1
ENST00000304129.9
AFAP1L2
actin filament associated protein 1 like 2
chr7_-_106661148 0.58 ENST00000523505.3
CCDC71L
coiled-coil domain containing 71 like
chr15_-_55917129 0.58 ENST00000338963.6
ENST00000508342.5
NEDD4
NEDD4 E3 ubiquitin protein ligase
chr21_-_15064934 0.57 ENST00000400199.5
ENST00000400202.5
ENST00000318948.7
NRIP1
nuclear receptor interacting protein 1
chr2_+_48314637 0.57 ENST00000413569.5
ENST00000340553.8
FOXN2
forkhead box N2
chr5_-_160312524 0.57 ENST00000520748.1
ENST00000257536.13
ENST00000393977.7
CCNJL
cyclin J like
chr17_-_35121487 0.56 ENST00000593039.5
ENSG00000267618.5
RAD51L3-RFFL readthrough
chr20_-_62407274 0.56 ENST00000279101.9
CABLES2
Cdk5 and Abl enzyme substrate 2
chr18_+_22169580 0.56 ENST00000269216.10
GATA6
GATA binding protein 6
chr6_-_40587314 0.55 ENST00000338305.7
LRFN2
leucine rich repeat and fibronectin type III domain containing 2
chr11_+_63813384 0.55 ENST00000294244.9
SPINDOC
spindlin interactor and repressor of chromatin binding
chr6_+_106098933 0.54 ENST00000369089.3
PRDM1
PR/SET domain 1
chr8_-_94896660 0.53 ENST00000520509.5
CCNE2
cyclin E2
chr20_-_54173976 0.53 ENST00000216862.8
CYP24A1
cytochrome P450 family 24 subfamily A member 1
chr3_+_183253230 0.52 ENST00000326505.4
B3GNT5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr8_-_123541197 0.51 ENST00000517956.5
ENST00000443022.2
FBXO32
F-box protein 32
chr22_-_38700655 0.51 ENST00000216039.9
JOSD1
Josephin domain containing 1
chr1_+_204073104 0.50 ENST00000367204.6
SOX13
SRY-box transcription factor 13
chr9_+_100442271 0.50 ENST00000502978.1
MSANTD3-TMEFF1
MSANTD3-TMEFF1 readthrough
chr6_-_42451910 0.50 ENST00000372922.8
ENST00000541110.5
TRERF1
transcriptional regulating factor 1
chr22_+_39994926 0.49 ENST00000333407.11
FAM83F
family with sequence similarity 83 member F
chr18_-_31684504 0.48 ENST00000383131.3
ENST00000237019.11
ENST00000306851.10
B4GALT6
beta-1,4-galactosyltransferase 6
chr6_-_33746848 0.47 ENST00000634274.1
ENST00000293756.5
ENST00000451316.6
IP6K3
inositol hexakisphosphate kinase 3
chr17_-_78360066 0.47 ENST00000587578.1
ENST00000330871.3
SOCS3
suppressor of cytokine signaling 3
chr7_-_112939773 0.47 ENST00000297145.9
BMT2
base methyltransferase of 25S rRNA 2 homolog
chr6_+_146543824 0.46 ENST00000367495.4
RAB32
RAB32, member RAS oncogene family
chr3_+_141487008 0.46 ENST00000286364.9
ENST00000452898.2
RASA2
RAS p21 protein activator 2
chr5_-_132227808 0.45 ENST00000401867.5
ENST00000379086.5
ENST00000379100.7
ENST00000418055.5
ENST00000453286.5
ENST00000360568.8
ENST00000379104.7
ENST00000166534.8
P4HA2
prolyl 4-hydroxylase subunit alpha 2
chr20_+_43667105 0.45 ENST00000217026.5
MYBL2
MYB proto-oncogene like 2
chr5_+_52989314 0.44 ENST00000296585.10
ITGA2
integrin subunit alpha 2
chr8_+_57994455 0.44 ENST00000361488.7
FAM110B
family with sequence similarity 110 member B
chr1_+_116909869 0.43 ENST00000393203.3
PTGFRN
prostaglandin F2 receptor inhibitor
chr8_-_65842051 0.43 ENST00000401827.8
PDE7A
phosphodiesterase 7A
chr6_-_45377860 0.43 ENST00000371460.5
ENST00000371459.6
SUPT3H
SPT3 homolog, SAGA and STAGA complex component
chr20_-_5610980 0.43 ENST00000379019.7
GPCPD1
glycerophosphocholine phosphodiesterase 1
chr2_-_165794190 0.43 ENST00000392701.8
ENST00000422973.1
GALNT3
polypeptide N-acetylgalactosaminyltransferase 3
chr14_+_54567612 0.41 ENST00000251091.9
ENST00000392067.7
ENST00000631086.2
SAMD4A
sterile alpha motif domain containing 4A
chr4_-_52038260 0.40 ENST00000381431.10
SGCB
sarcoglycan beta
chr17_-_35089212 0.40 ENST00000584655.5
ENST00000447669.6
ENST00000315249.11
RFFL
ring finger and FYVE like domain containing E3 ubiquitin protein ligase
chrX_-_15335407 0.40 ENST00000635543.1
ENST00000542278.6
ENST00000482148.6
ENST00000333590.6
ENST00000637296.1
ENST00000634582.1
ENST00000634640.1
PIGA
phosphatidylinositol glycan anchor biosynthesis class A
chrX_+_118346072 0.40 ENST00000371822.9
ENST00000254029.8
ENST00000371825.7
WDR44
WD repeat domain 44
chr19_-_344786 0.40 ENST00000264819.7
MIER2
MIER family member 2
chr20_+_325536 0.39 ENST00000342665.5
SOX12
SRY-box transcription factor 12
chr14_+_103385506 0.39 ENST00000303622.13
MARK3
microtubule affinity regulating kinase 3
chr10_+_119207560 0.38 ENST00000392870.3
GRK5
G protein-coupled receptor kinase 5
chr21_+_29298890 0.38 ENST00000286800.8
BACH1
BTB domain and CNC homolog 1
chr1_-_208244375 0.38 ENST00000367033.4
PLXNA2
plexin A2
chr21_+_38256698 0.37 ENST00000613499.4
ENST00000612702.4
ENST00000398925.5
ENST00000398928.5
ENST00000328656.8
ENST00000443341.5
KCNJ15
potassium inwardly rectifying channel subfamily J member 15
chr4_-_113761927 0.37 ENST00000296402.9
CAMK2D
calcium/calmodulin dependent protein kinase II delta
chr6_-_108074703 0.37 ENST00000193322.8
OSTM1
osteoclastogenesis associated transmembrane protein 1
chr10_-_103855406 0.37 ENST00000355946.6
ENST00000369774.8
SH3PXD2A
SH3 and PX domains 2A
chr5_+_56909586 0.36 ENST00000285947.5
SETD9
SET domain containing 9
chr13_-_72727600 0.36 ENST00000377818.4
MZT1
mitotic spindle organizing protein 1
chr14_-_68979436 0.36 ENST00000193403.10
ACTN1
actinin alpha 1
chr18_-_12702712 0.36 ENST00000423709.6
ENST00000262127.7
CEP76
centrosomal protein 76
chr19_+_34254543 0.36 ENST00000588470.5
ENST00000299505.8
ENST00000589583.5
GARRE1
granule associated Rac and RHOG effector 1
chr5_+_36152077 0.35 ENST00000546211.6
ENST00000620197.5
ENST00000678270.1
ENST00000679015.1
ENST00000678580.1
ENST00000274255.11
ENST00000508514.5
SKP2
S-phase kinase associated protein 2
chr7_+_18495723 0.35 ENST00000681950.1
ENST00000622668.4
ENST00000405010.7
ENST00000406451.8
ENST00000441542.7
ENST00000428307.6
ENST00000681273.1
HDAC9
histone deacetylase 9
chr3_-_9249623 0.35 ENST00000383836.8
SRGAP3
SLIT-ROBO Rho GTPase activating protein 3
chr12_-_53232182 0.35 ENST00000425354.7
ENST00000546717.1
ENST00000394426.5
RARG
retinoic acid receptor gamma
chr3_+_49554436 0.34 ENST00000296452.5
BSN
bassoon presynaptic cytomatrix protein
chr5_+_34656288 0.34 ENST00000265109.8
RAI14
retinoic acid induced 14
chr1_+_233327710 0.34 ENST00000366624.8
MAP3K21
mitogen-activated protein kinase kinase kinase 21
chr12_+_103965863 0.34 ENST00000392872.8
ENST00000537100.5
TDG
thymine DNA glycosylase
chr14_-_23578756 0.33 ENST00000397118.7
ENST00000356300.9
JPH4
junctophilin 4
chr1_-_197201262 0.33 ENST00000367405.5
ZBTB41
zinc finger and BTB domain containing 41
chr9_-_27573391 0.33 ENST00000644136.1
ENST00000380003.8
C9orf72
C9orf72-SMCR8 complex subunit
chr14_-_34713788 0.33 ENST00000341223.8
CFL2
cofilin 2
chr2_+_135531460 0.33 ENST00000683871.1
ENST00000409478.5
ENST00000264160.8
ENST00000438014.5
R3HDM1
R3H domain containing 1
chr2_-_230068905 0.33 ENST00000457406.5
ENST00000295190.9
SLC16A14
solute carrier family 16 member 14
chr10_-_22714531 0.33 ENST00000376573.9
PIP4K2A
phosphatidylinositol-5-phosphate 4-kinase type 2 alpha
chr12_-_113471851 0.32 ENST00000261731.4
LHX5
LIM homeobox 5
chr8_-_81842192 0.32 ENST00000353788.8
ENST00000520618.5
ENST00000518183.5
ENST00000396330.6
ENST00000519119.5
SNX16
sorting nexin 16
chr3_-_27456743 0.32 ENST00000295736.9
ENST00000428386.5
ENST00000428179.1
SLC4A7
solute carrier family 4 member 7
chr2_-_68252482 0.32 ENST00000234310.8
PPP3R1
protein phosphatase 3 regulatory subunit B, alpha
chr3_+_172040554 0.32 ENST00000336824.8
ENST00000423424.5
FNDC3B
fibronectin type III domain containing 3B
chr17_-_30824665 0.31 ENST00000324238.7
CRLF3
cytokine receptor like factor 3
chr1_+_70411180 0.31 ENST00000411986.6
CTH
cystathionine gamma-lyase
chr22_+_20917398 0.31 ENST00000354336.8
CRKL
CRK like proto-oncogene, adaptor protein
chr17_-_55421818 0.31 ENST00000262065.8
ENST00000649377.1
MMD
monocyte to macrophage differentiation associated
chr6_+_107490103 0.31 ENST00000317357.10
SOBP
sine oculis binding protein homolog
chr7_-_2314365 0.31 ENST00000222990.8
SNX8
sorting nexin 8
chr12_-_77065526 0.31 ENST00000547316.1
ENST00000416496.6
ENST00000550669.5
ENST00000322886.12
E2F7
E2F transcription factor 7
chr1_+_200027702 0.31 ENST00000367362.8
NR5A2
nuclear receptor subfamily 5 group A member 2
chr14_+_36661852 0.30 ENST00000361487.7
PAX9
paired box 9
chr1_-_84690406 0.30 ENST00000605755.5
ENST00000342203.8
ENST00000437941.6
SSX2IP
SSX family member 2 interacting protein
chr10_-_33334625 0.30 ENST00000374875.5
ENST00000374822.8
ENST00000374867.7
NRP1
neuropilin 1
chr1_+_89633086 0.30 ENST00000370454.9
LRRC8C
leucine rich repeat containing 8 VRAC subunit C
chr6_+_15246054 0.30 ENST00000341776.7
JARID2
jumonji and AT-rich interaction domain containing 2
chr2_-_234497035 0.30 ENST00000390645.2
ENST00000339728.6
ARL4C
ADP ribosylation factor like GTPase 4C
chr12_+_111405861 0.29 ENST00000341259.7
SH2B3
SH2B adaptor protein 3
chr18_+_33578213 0.29 ENST00000681521.1
ENST00000269197.12
ASXL3
ASXL transcriptional regulator 3
chr17_-_43022350 0.29 ENST00000587173.5
ENST00000355653.8
VAT1
vesicle amine transport 1
chrX_-_75156272 0.29 ENST00000620875.5
ENST00000669573.1
ENST00000339447.8
ENST00000645829.3
ENST00000529949.5
ENST00000373394.8
ENST00000253577.9
ENST00000644766.1
ENST00000534524.5
ABCB7
ATP binding cassette subfamily B member 7
chr4_+_176319942 0.28 ENST00000503362.2
SPCS3
signal peptidase complex subunit 3
chr15_+_26867047 0.28 ENST00000335625.10
ENST00000555182.5
ENST00000400081.7
GABRA5
gamma-aminobutyric acid type A receptor subunit alpha5
chr1_-_115089414 0.28 ENST00000433172.3
ENST00000369515.6
ENST00000369516.7
TSPAN2
tetraspanin 2
chr13_-_35476682 0.28 ENST00000379919.6
MAB21L1
mab-21 like 1
chr12_-_42238203 0.28 ENST00000327791.8
ENST00000534854.7
YAF2
YY1 associated factor 2
chr15_-_34210073 0.28 ENST00000559515.1
ENST00000560108.5
ENST00000256544.8
ENST00000559462.1
KATNBL1
katanin regulatory subunit B1 like 1
chr2_+_152718604 0.28 ENST00000326446.10
ARL6IP6
ADP ribosylation factor like GTPase 6 interacting protein 6
chr7_-_134316912 0.28 ENST00000378509.9
SLC35B4
solute carrier family 35 member B4
chr16_-_84618067 0.27 ENST00000262428.5
COTL1
coactosin like F-actin binding protein 1
chr12_-_112108743 0.27 ENST00000547133.1
ENST00000261745.9
NAA25
N-alpha-acetyltransferase 25, NatB auxiliary subunit
chr7_+_77798750 0.27 ENST00000416283.6
ENST00000422959.6
ENST00000307305.12
ENST00000424760.5
PHTF2
putative homeodomain transcription factor 2
chr2_-_64144411 0.27 ENST00000358912.5
PELI1
pellino E3 ubiquitin protein ligase 1
chr3_+_50236192 0.27 ENST00000313601.11
GNAI2
G protein subunit alpha i2
chr2_-_38751350 0.27 ENST00000409276.5
ENST00000313117.11
ENST00000446327.6
SRSF7
serine and arginine rich splicing factor 7
chr10_+_111077021 0.26 ENST00000280155.4
ADRA2A
adrenoceptor alpha 2A
chr15_-_52529050 0.26 ENST00000399231.7
MYO5A
myosin VA
chr1_+_32817645 0.26 ENST00000526230.1
ENST00000373475.10
ENST00000531256.1
ENST00000482212.1
S100PBP
S100P binding protein
chr6_-_57221402 0.26 ENST00000317483.4
RAB23
RAB23, member RAS oncogene family
chr12_+_50504970 0.26 ENST00000301180.10
DIP2B
disco interacting protein 2 homolog B
chr2_-_61538313 0.26 ENST00000677803.1
ENST00000677239.1
ENST00000401558.7
XPO1
exportin 1
chr13_+_99981775 0.26 ENST00000376335.8
ZIC2
Zic family member 2
chr2_+_9961165 0.25 ENST00000405379.6
GRHL1
grainyhead like transcription factor 1
chr1_+_6613722 0.25 ENST00000377648.5
PHF13
PHD finger protein 13
chr17_-_78874140 0.24 ENST00000585421.5
TIMP2
TIMP metallopeptidase inhibitor 2
chr3_-_101677119 0.24 ENST00000312938.5
ZBTB11
zinc finger and BTB domain containing 11
chrX_-_132218124 0.24 ENST00000342983.6
RAP2C
RAP2C, member of RAS oncogene family
chr8_+_42896883 0.24 ENST00000307602.9
HOOK3
hook microtubule tethering protein 3
chr6_+_124962420 0.23 ENST00000521654.7
ENST00000560949.5
RNF217
ring finger protein 217
chr17_+_44557476 0.23 ENST00000315323.5
FZD2
frizzled class receptor 2
chr11_+_112961402 0.23 ENST00000613217.4
ENST00000316851.12
ENST00000620046.4
ENST00000531044.5
ENST00000529356.5
NCAM1
neural cell adhesion molecule 1
chr4_-_72569204 0.23 ENST00000286657.10
ADAMTS3
ADAM metallopeptidase with thrombospondin type 1 motif 3
chr2_-_208255055 0.23 ENST00000345146.7
IDH1
isocitrate dehydrogenase (NADP(+)) 1
chr12_-_38905584 0.23 ENST00000331366.10
CPNE8
copine 8
chr10_+_87504867 0.22 ENST00000371994.8
MINPP1
multiple inositol-polyphosphate phosphatase 1
chr19_+_3224701 0.22 ENST00000541430.6
CELF5
CUGBP Elav-like family member 5
chr6_+_20401864 0.22 ENST00000346618.8
ENST00000613242.4
E2F3
E2F transcription factor 3
chr10_+_63133279 0.22 ENST00000277746.11
NRBF2
nuclear receptor binding factor 2
chr6_-_83431038 0.22 ENST00000369705.4
ME1
malic enzyme 1
chr3_+_196867856 0.22 ENST00000445299.6
ENST00000323460.10
ENST00000419026.5
SENP5
SUMO specific peptidase 5
chr1_+_215567279 0.22 ENST00000259154.9
KCTD3
potassium channel tetramerization domain containing 3
chr12_-_46268989 0.22 ENST00000549049.5
ENST00000439706.5
ENST00000398637.10
SLC38A1
solute carrier family 38 member 1
chr5_+_115841878 0.22 ENST00000316788.12
AP3S1
adaptor related protein complex 3 subunit sigma 1
chr16_+_46884323 0.22 ENST00000340124.9
GPT2
glutamic--pyruvic transaminase 2
chr11_-_134411854 0.22 ENST00000392580.5
B3GAT1
beta-1,3-glucuronyltransferase 1
chr1_+_173714908 0.22 ENST00000209884.5
KLHL20
kelch like family member 20
chr6_+_123803853 0.21 ENST00000368417.6
NKAIN2
sodium/potassium transporting ATPase interacting 2
chr9_+_33817126 0.21 ENST00000263228.4
UBE2R2
ubiquitin conjugating enzyme E2 R2
chr12_+_62260338 0.21 ENST00000353364.7
ENST00000549523.5
USP15
ubiquitin specific peptidase 15
chr7_+_139231225 0.21 ENST00000473989.8
UBN2
ubinuclein 2
chr5_+_90474879 0.21 ENST00000504930.5
ENST00000514483.5
POLR3G
RNA polymerase III subunit G
chr2_-_196171565 0.21 ENST00000263955.9
STK17B
serine/threonine kinase 17b
chr10_+_75111595 0.21 ENST00000671800.1
ENST00000542569.6
ENST00000372687.4
SAMD8
sterile alpha motif domain containing 8
chr11_-_117098415 0.21 ENST00000445177.6
ENST00000375300.6
ENST00000446921.6
SIK3
SIK family kinase 3
chr6_+_150143018 0.21 ENST00000361131.5
PPP1R14C
protein phosphatase 1 regulatory inhibitor subunit 14C
chr17_-_44689725 0.21 ENST00000588687.5
ENST00000588210.1
ENST00000315286.13
ENST00000457422.6
CCDC43
coiled-coil domain containing 43
chr17_-_65056659 0.20 ENST00000439174.7
GNA13
G protein subunit alpha 13
chr2_+_28392802 0.20 ENST00000379619.5
ENST00000264716.9
FOSL2
FOS like 2, AP-1 transcription factor subunit
chr6_+_143608170 0.20 ENST00000427704.6
ENST00000305766.10
PHACTR2
phosphatase and actin regulator 2
chr9_-_70414657 0.20 ENST00000377126.4
KLF9
Kruppel like factor 9
chr1_+_112674416 0.20 ENST00000413052.6
ENST00000369645.5
MOV10
Mov10 RISC complex RNA helicase
chr4_+_25312766 0.20 ENST00000302874.9
ENST00000612982.1
ZCCHC4
zinc finger CCHC-type containing 4
chr1_-_109041986 0.20 ENST00000400794.7
ENST00000528747.1
ENST00000361054.7
WDR47
WD repeat domain 47
chr4_-_109729987 0.20 ENST00000243501.10
PLA2G12A
phospholipase A2 group XIIA
chr14_-_45253161 0.20 ENST00000451174.1
ENST00000310806.9
MIS18BP1
MIS18 binding protein 1
chr16_-_20900319 0.20 ENST00000564349.5
ENST00000324344.9
ERI2
DCUN1D3
ERI1 exoribonuclease family member 2
defective in cullin neddylation 1 domain containing 3
chr2_-_226799806 0.20 ENST00000305123.6
IRS1
insulin receptor substrate 1
chrX_+_150983299 0.20 ENST00000325307.12
HMGB3
high mobility group box 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:2000097 chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.4 1.1 GO:0060279 positive regulation of ovulation(GO:0060279)
0.3 1.7 GO:0046086 AMP catabolic process(GO:0006196) adenosine biosynthetic process(GO:0046086)
0.2 1.2 GO:0021828 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.2 1.4 GO:1903232 melanosome assembly(GO:1903232)
0.2 0.7 GO:0072034 primary prostatic bud elongation(GO:0060516) renal vesicle induction(GO:0072034)
0.2 0.6 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.2 0.6 GO:0044007 negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010768) transmission of virus(GO:0019089) dissemination or transmission of symbiont from host(GO:0044007) dissemination or transmission of organism from other organism involved in symbiotic interaction(GO:0051821)
0.2 1.3 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.2 0.6 GO:0032912 negative regulation of transforming growth factor beta2 production(GO:0032912)
0.2 0.7 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.2 0.5 GO:1990654 regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
0.1 0.6 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.1 0.5 GO:0042369 vitamin D catabolic process(GO:0042369)
0.1 0.4 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 0.7 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.1 0.5 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.4 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.1 1.5 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.1 0.3 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877) negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.1 0.7 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 0.3 GO:1990569 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.1 0.3 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.1 0.3 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.1 0.7 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 0.2 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.1 0.2 GO:0006097 glyoxylate cycle(GO:0006097)
0.1 0.4 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 1.0 GO:0045176 apical protein localization(GO:0045176)
0.1 0.3 GO:0035625 negative regulation of epinephrine secretion(GO:0032811) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.1 0.2 GO:1901420 negative regulation of prostaglandin biosynthetic process(GO:0031393) negative regulation of helicase activity(GO:0051097) negative regulation of response to alcohol(GO:1901420)
0.1 0.3 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.1 0.5 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.1 0.3 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.1 0.4 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.1 0.5 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1 0.2 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.1 0.1 GO:1904616 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.1 0.3 GO:2001271 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.3 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.1 0.1 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.1 0.3 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.2 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.3 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.1 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.0 0.4 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.0 0.1 GO:0089709 histidine transport(GO:0015817) L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.0 0.6 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.3 GO:0014004 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.0 0.2 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.0 0.2 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.2 GO:0042853 L-alanine metabolic process(GO:0042851) L-alanine catabolic process(GO:0042853)
0.0 0.2 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.2 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366) diapedesis(GO:0050904)
0.0 0.1 GO:0071206 establishment of protein localization to juxtaparanode region of axon(GO:0071206)
0.0 0.7 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.7 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.5 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.2 GO:1901300 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300)
0.0 0.2 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.2 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.0 1.2 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.4 GO:0015886 heme transport(GO:0015886)
0.0 0.5 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.3 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.4 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.1 GO:0070898 RNA polymerase III transcriptional preinitiation complex assembly(GO:0070898)
0.0 0.2 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.4 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.0 0.3 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.1 GO:0035552 oxidative single-stranded DNA demethylation(GO:0035552)
0.0 0.1 GO:0035910 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.0 0.4 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.4 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.4 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.7 GO:0060019 radial glial cell differentiation(GO:0060019)
0.0 0.4 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.2 GO:0003150 muscular septum morphogenesis(GO:0003150)
0.0 0.1 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0 0.3 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.1 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.1 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.0 0.1 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609)
0.0 0.2 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.2 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.1 GO:0060374 mast cell differentiation(GO:0060374)
0.0 0.2 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.1 GO:0051228 mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.0 0.1 GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
0.0 0.2 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.3 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.2 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.1 GO:0002727 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
0.0 0.2 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.1 GO:0061535 glutamate secretion, neurotransmission(GO:0061535) regulation of glutamate secretion, neurotransmission(GO:1903294) positive regulation of glutamate secretion, neurotransmission(GO:1903296)
0.0 0.2 GO:0016078 tRNA catabolic process(GO:0016078)
0.0 0.4 GO:1901725 regulation of histone deacetylase activity(GO:1901725)
0.0 0.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.1 GO:0003162 atrioventricular node development(GO:0003162)
0.0 0.2 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.0 0.2 GO:0051414 response to cortisol(GO:0051414)
0.0 0.6 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.1 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.2 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.2 GO:0002934 desmosome organization(GO:0002934)
0.0 0.3 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.0 0.1 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.3 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0 0.3 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.1 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.1 GO:0006532 fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
0.0 0.2 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.3 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.3 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.0 GO:0021897 forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897)
0.0 0.1 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.1 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.0 0.4 GO:0045116 protein neddylation(GO:0045116)
0.0 0.4 GO:0046599 regulation of centriole replication(GO:0046599)
0.0 0.3 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.1 GO:0061085 regulation of histone H3-K27 methylation(GO:0061085) positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.3 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.1 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 0.2 GO:0019375 protein localization to paranode region of axon(GO:0002175) galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.0 0.1 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.5 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.1 GO:0015888 thiamine transport(GO:0015888)
0.0 0.1 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.0 0.1 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.3 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.3 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.4 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.0 GO:0001828 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.0 0.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.4 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.3 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.8 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.1 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.2 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.2 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.1 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.1 GO:0034378 chylomicron assembly(GO:0034378)
0.0 0.1 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.2 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.1 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.0 0.1 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.1 GO:1900223 positive regulation of beta-amyloid clearance(GO:1900223)
0.0 0.6 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.6 GO:0032757 positive regulation of interleukin-8 production(GO:0032757)
0.0 0.0 GO:0002371 dendritic cell cytokine production(GO:0002371)
0.0 0.6 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.3 GO:0042481 regulation of odontogenesis(GO:0042481)
0.0 0.3 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.1 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.1 GO:0060613 fat pad development(GO:0060613)
0.0 0.1 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.0 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.0 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.4 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.5 GO:0090102 cochlea development(GO:0090102)
0.0 0.1 GO:0003383 apical constriction(GO:0003383)
0.0 0.6 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.0 0.0 GO:1904783 negative regulation of glutamate receptor signaling pathway(GO:1900450) negative regulation of NMDA glutamate receptor activity(GO:1904782) positive regulation of NMDA glutamate receptor activity(GO:1904783)
0.0 0.3 GO:0016578 histone deubiquitination(GO:0016578)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.3 1.3 GO:0031905 early endosome lumen(GO:0031905)
0.2 0.5 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.1 0.5 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.1 0.4 GO:0031523 Myb complex(GO:0031523)
0.1 0.2 GO:0016939 kinesin II complex(GO:0016939)
0.1 0.2 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.1 0.2 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.1 0.3 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.1 0.2 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.7 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.4 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 1.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.4 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.2 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.4 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.7 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.3 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.0 0.1 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.3 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.1 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.0 0.1 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.3 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.3 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.0 0.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.0 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.2 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 0.3 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.1 GO:0035363 histone locus body(GO:0035363)
0.0 0.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.2 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 1.6 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 1.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 1.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.6 GO:0097542 ciliary tip(GO:0097542)
0.0 0.0 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.1 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0035650 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.4 1.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.3 1.4 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.3 1.6 GO:1990254 keratin filament binding(GO:1990254)
0.2 0.5 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1 1.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.4 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.5 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.1 0.3 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.1 0.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.5 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.1 0.6 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.1 0.3 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.1 0.3 GO:0031696 alpha2-adrenergic receptor activity(GO:0004938) alpha-2C adrenergic receptor binding(GO:0031696)
0.1 1.7 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.2 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450) (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.1 0.2 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416) inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717)
0.1 0.2 GO:0004021 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
0.1 0.6 GO:0050816 phosphoserine binding(GO:0050815) phosphothreonine binding(GO:0050816)
0.1 0.3 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.3 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 0.4 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 0.3 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.5 GO:0016433 rRNA (adenine) methyltransferase activity(GO:0016433)
0.1 0.9 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.4 GO:0038064 collagen receptor activity(GO:0038064) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.2 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.7 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.7 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.2 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.4 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.2 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.2 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.4 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.2 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 1.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.1 GO:0035514 DNA demethylase activity(GO:0035514)
0.0 0.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.1 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.2 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.4 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0 0.1 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.0 0.7 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.2 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.1 GO:0001156 TFIIIB-type transcription factor activity(GO:0001026) TFIIIC-class transcription factor binding(GO:0001156)
0.0 0.5 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.9 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.1 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.2 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.1 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.1 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.2 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.2 GO:1990405 protein antigen binding(GO:1990405)
0.0 0.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.1 GO:0098808 mRNA cap binding(GO:0098808)
0.0 0.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.7 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.0 0.1 GO:0004515 nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.1 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.0 0.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.8 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.3 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.7 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.8 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.6 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.2 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0004905 type I interferon receptor activity(GO:0004905)
0.0 0.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.1 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.1 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.0 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.1 PID AURORA B PATHWAY Aurora B signaling
0.0 0.5 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.0 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.9 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.6 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 1.1 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.8 PID MYC PATHWAY C-MYC pathway
0.0 0.4 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 1.5 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.9 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.1 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.1 PID E2F PATHWAY E2F transcription factor network
0.0 0.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.6 PID FOXO PATHWAY FoxO family signaling
0.0 0.5 PID IL23 PATHWAY IL23-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.7 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 1.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 1.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.4 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 1.1 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.8 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 1.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.7 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.3 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.9 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.6 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 1.0 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.7 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 1.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.7 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.3 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.5 REACTOME GABA B RECEPTOR ACTIVATION Genes involved in GABA B receptor activation
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.5 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.1 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.3 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation