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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for GZF1

Z-value: 0.25

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Transcription factors associated with GZF1

Gene Symbol Gene ID Gene Info
GZF1
ENSG00000125812.16 GZF1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GZF1hg38_v1_chr20_+_23362144_233623200.173.6e-01Click!

Activity profile of GZF1 motif

Sorted Z-values of GZF1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GZF1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr6_-_33080710 1.33 ENST00000419277.5
HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
chr6_+_33080445 1.08 ENST00000428835.5
HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr11_+_102047422 0.79 ENST00000434758.7
ENST00000526781.5
ENST00000534360.1
CFAP300
cilia and flagella associated protein 300
chr1_+_78649818 0.50 ENST00000370747.9
ENST00000438486.1
IFI44
interferon induced protein 44
chr1_-_32336224 0.30 ENST00000329421.8
MARCKSL1
MARCKS like 1
chr18_-_55635948 0.26 ENST00000565124.4
ENST00000398339.5
TCF4
transcription factor 4
chr14_-_21511290 0.23 ENST00000298717.9
METTL3
methyltransferase like 3
chr12_+_104064520 0.23 ENST00000229330.9
HCFC2
host cell factor C2
chr19_+_12995554 0.22 ENST00000397661.6
NFIX
nuclear factor I X
chr19_-_36054224 0.21 ENST00000292894.2
THAP8
THAP domain containing 8
chr3_-_79767987 0.21 ENST00000464233.6
ROBO1
roundabout guidance receptor 1
chr19_+_12995467 0.19 ENST00000592199.6
NFIX
nuclear factor I X
chr16_-_1611985 0.16 ENST00000426508.7
IFT140
intraflagellar transport 140
chr14_-_53153098 0.14 ENST00000612692.4
ENST00000395606.5
DDHD1
DDHD domain containing 1
chr14_-_31457495 0.14 ENST00000310850.9
DTD2
D-aminoacyl-tRNA deacylase 2
chr14_-_31457417 0.13 ENST00000356180.4
DTD2
D-aminoacyl-tRNA deacylase 2
chr7_-_6706843 0.12 ENST00000394917.3
ENST00000342651.9
ENST00000405858.6
ZNF12
zinc finger protein 12
chr1_+_40709475 0.11 ENST00000372651.5
NFYC
nuclear transcription factor Y subunit gamma
chrX_+_103628692 0.10 ENST00000372626.7
TCEAL1
transcription elongation factor A like 1
chr4_+_26343156 0.10 ENST00000680928.1
ENST00000681260.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr19_+_35666515 0.10 ENST00000617999.4
ENST00000616789.4
UPK1A
uroplakin 1A
chr16_+_67842277 0.10 ENST00000303596.3
THAP11
THAP domain containing 11
chr19_-_10315737 0.10 ENST00000492239.5
FDX2
ferredoxin 2
chr14_-_53153281 0.10 ENST00000357758.3
ENST00000673822.2
DDHD1
DDHD domain containing 1
chr14_-_52069228 0.08 ENST00000617139.4
NID2
nidogen 2
chr14_-_52069039 0.07 ENST00000216286.10
NID2
nidogen 2
chr16_+_1612337 0.06 ENST00000674071.1
ENST00000397412.8
CRAMP1
cramped chromatin regulator homolog 1
chr19_+_38390055 0.06 ENST00000587947.5
ENST00000338502.8
SPRED3
sprouty related EVH1 domain containing 3
chr19_-_10315987 0.06 ENST00000393708.3
ENST00000494368.5
FDX2
ferredoxin 2
chr1_+_40709316 0.06 ENST00000372652.5
NFYC
nuclear transcription factor Y subunit gamma
chr16_-_46763237 0.05 ENST00000536476.5
MYLK3
myosin light chain kinase 3
chr1_-_2530256 0.05 ENST00000378453.4
HES5
hes family bHLH transcription factor 5
chr14_-_53152371 0.05 ENST00000323669.10
DDHD1
DDHD domain containing 1
chrX_+_153972729 0.05 ENST00000369982.5
TMEM187
transmembrane protein 187
chr10_-_102120246 0.05 ENST00000425280.2
LDB1
LIM domain binding 1
chr3_+_30606574 0.04 ENST00000295754.10
ENST00000359013.4
TGFBR2
transforming growth factor beta receptor 2
chr10_+_58269132 0.03 ENST00000333926.6
CISD1
CDGSH iron sulfur domain 1
chr9_-_14307928 0.03 ENST00000637640.1
ENST00000493697.1
ENST00000636057.1
NFIB
nuclear factor I B
chr10_-_125160499 0.03 ENST00000494626.6
ENST00000337195.9
CTBP2
C-terminal binding protein 2
chr10_-_125161019 0.03 ENST00000411419.6
CTBP2
C-terminal binding protein 2
chr4_-_47463649 0.03 ENST00000381571.6
COMMD8
COMM domain containing 8
chr4_-_146521891 0.03 ENST00000394059.8
ENST00000502607.1
ENST00000335472.12
ENST00000432059.6
SLC10A7
solute carrier family 10 member 7
chr6_-_36547400 0.03 ENST00000229812.8
STK38
serine/threonine kinase 38
chr11_-_17476801 0.03 ENST00000644772.1
ENST00000642271.1
ENST00000684571.1
ENST00000646902.1
ENST00000647015.1
ENST00000302539.9
ENST00000389817.8
ENST00000643260.1
ENST00000683136.1
ABCC8
ATP binding cassette subfamily C member 8
chr3_+_51671175 0.02 ENST00000614067.4
ENST00000457573.5
ENST00000611400.4
ENST00000412249.5
ENST00000425781.5
ENST00000341333.10
ENST00000415259.5
ENST00000395057.5
ENST00000416589.5
TEX264
testis expressed 264, ER-phagy receptor
chr19_-_3786408 0.02 ENST00000395040.6
MATK
megakaryocyte-associated tyrosine kinase
chr10_-_102120318 0.02 ENST00000673968.1
LDB1
LIM domain binding 1
chr20_-_32743406 0.02 ENST00000474815.2
ENST00000446419.6
ENST00000278980.11
ENST00000642484.1
ENST00000646357.1
COMMD7
ENSG00000285382.1
COMM domain containing 7
novel protein
chr22_-_42959852 0.02 ENST00000402229.5
ENST00000407585.5
ENST00000453079.1
PACSIN2
protein kinase C and casein kinase substrate in neurons 2
chrX_+_81202066 0.02 ENST00000373212.6
SH3BGRL
SH3 domain binding glutamate rich protein like
chr19_-_3786363 0.01 ENST00000310132.11
MATK
megakaryocyte-associated tyrosine kinase
chr10_-_14838561 0.00 ENST00000378442.5
CDNF
cerebral dopamine neurotrophic factor

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0021827 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) negative regulation of negative chemotaxis(GO:0050925)
0.0 0.2 GO:1903677 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.0 2.4 GO:0032729 positive regulation of interferon-gamma production(GO:0032729)
0.0 0.1 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.0 0.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.0 GO:0042668 auditory receptor cell fate determination(GO:0042668) negative regulation of pro-B cell differentiation(GO:2000974)
0.0 0.3 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.1 GO:1901297 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.2 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.0 GO:0060434 bronchus morphogenesis(GO:0060434)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.2 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.2 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 0.3 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 1.1 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.0 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse