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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for HAND1

Z-value: 0.58

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Transcription factors associated with HAND1

Gene Symbol Gene ID Gene Info
HAND1
ENSG00000113196.3 HAND1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HAND1hg38_v1_chr5_-_154478218_1544782340.232.2e-01Click!

Activity profile of HAND1 motif

Sorted Z-values of HAND1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HAND1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr2_+_209579399 1.04 ENST00000360351.8
MAP2
microtubule associated protein 2
chr2_+_209579598 1.03 ENST00000445941.5
ENST00000673860.1
MAP2
microtubule associated protein 2
chr10_+_132036652 0.88 ENST00000657785.1
JAKMIP3
Janus kinase and microtubule interacting protein 3
chr6_+_123804141 0.83 ENST00000368416.5
NKAIN2
sodium/potassium transporting ATPase interacting 2
chr6_-_30684744 0.81 ENST00000615892.4
PPP1R18
protein phosphatase 1 regulatory subunit 18
chr7_+_111091006 0.74 ENST00000451085.5
ENST00000422987.3
ENST00000421101.1
LRRN3
leucine rich repeat neuronal 3
chr7_+_111091119 0.73 ENST00000308478.10
LRRN3
leucine rich repeat neuronal 3
chr11_-_102625332 0.68 ENST00000260228.3
MMP20
matrix metallopeptidase 20
chr6_-_111873421 0.68 ENST00000368678.8
ENST00000523238.5
ENST00000354650.7
FYN
FYN proto-oncogene, Src family tyrosine kinase
chr2_-_196926717 0.68 ENST00000409475.5
ENST00000374738.3
PGAP1
post-GPI attachment to proteins inositol deacylase 1
chr20_-_57710539 0.66 ENST00000395816.7
ENST00000347215.8
PMEPA1
prostate transmembrane protein, androgen induced 1
chr2_+_227813834 0.64 ENST00000358813.5
ENST00000409189.7
CCL20
C-C motif chemokine ligand 20
chr2_-_27495185 0.62 ENST00000264703.4
FNDC4
fibronectin type III domain containing 4
chr1_+_65309517 0.61 ENST00000371069.5
DNAJC6
DnaJ heat shock protein family (Hsp40) member C6
chr9_-_136746006 0.58 ENST00000476567.1
LCN6
lipocalin 6
chr2_+_209579429 0.55 ENST00000361559.8
MAP2
microtubule associated protein 2
chr11_+_118956289 0.54 ENST00000264031.3
UPK2
uroplakin 2
chr22_+_24607638 0.53 ENST00000432867.5
GGT1
gamma-glutamyltransferase 1
chr10_+_132036336 0.53 ENST00000668452.1
JAKMIP3
Janus kinase and microtubule interacting protein 3
chr2_+_113058637 0.53 ENST00000346807.7
IL36RN
interleukin 36 receptor antagonist
chr2_+_203867943 0.50 ENST00000295854.10
ENST00000487393.1
ENST00000472206.1
CTLA4
cytotoxic T-lymphocyte associated protein 4
chr19_+_12751672 0.49 ENST00000549706.5
BEST2
bestrophin 2
chr22_+_24607658 0.48 ENST00000451366.5
ENST00000428855.5
GGT1
gamma-glutamyltransferase 1
chr15_-_89679360 0.47 ENST00000300055.10
PLIN1
perilipin 1
chr15_-_89679411 0.47 ENST00000430628.2
PLIN1
perilipin 1
chr19_+_12751789 0.46 ENST00000553030.6
BEST2
bestrophin 2
chr15_-_76012390 0.46 ENST00000394907.8
NRG4
neuregulin 4
chr22_+_24607602 0.45 ENST00000447416.5
GGT1
gamma-glutamyltransferase 1
chr19_+_35868585 0.44 ENST00000652533.1
APLP1
amyloid beta precursor like protein 1
chr10_-_116273606 0.44 ENST00000682743.1
GFRA1
GDNF family receptor alpha 1
chr19_+_35868518 0.43 ENST00000221891.9
APLP1
amyloid beta precursor like protein 1
chr7_-_117323041 0.42 ENST00000491214.1
ENST00000265441.8
WNT2
Wnt family member 2
chr12_+_49323236 0.40 ENST00000549275.5
ENST00000551245.5
ENST00000380327.9
ENST00000548311.5
ENST00000257909.8
ENST00000550346.5
ENST00000550709.5
ENST00000549534.1
ENST00000547807.5
ENST00000551567.1
TROAP
trophinin associated protein
chr9_+_35042213 0.38 ENST00000378745.3
ENST00000312292.6
C9orf131
chromosome 9 open reading frame 131
chr1_-_52404387 0.37 ENST00000371566.1
ENST00000371568.8
ORC1
origin recognition complex subunit 1
chr12_+_40692413 0.37 ENST00000551295.7
ENST00000547702.5
ENST00000551424.5
CNTN1
contactin 1
chr20_+_46029165 0.37 ENST00000616201.4
ENST00000616202.4
ENST00000616933.4
ENST00000626937.2
SLC12A5
solute carrier family 12 member 5
chr22_+_24603147 0.36 ENST00000412658.5
ENST00000445029.5
ENST00000400382.6
ENST00000419133.5
ENST00000438643.6
ENST00000452551.5
ENST00000412898.5
ENST00000400380.5
ENST00000455483.5
ENST00000430289.5
GGT1
gamma-glutamyltransferase 1
chr12_+_25958891 0.36 ENST00000381352.7
ENST00000535907.5
ENST00000405154.6
ENST00000615708.4
RASSF8
Ras association domain family member 8
chr12_-_10802627 0.35 ENST00000240687.2
TAS2R7
taste 2 receptor member 7
chr17_-_44947637 0.35 ENST00000587309.5
ENST00000593135.6
KIF18B
kinesin family member 18B
chr17_+_45844875 0.35 ENST00000329196.7
SPPL2C
signal peptide peptidase like 2C
chrX_+_50067576 0.32 ENST00000376108.7
CLCN5
chloride voltage-gated channel 5
chr19_+_507487 0.32 ENST00000359315.6
TPGS1
tubulin polyglutamylase complex subunit 1
chr17_-_8210203 0.32 ENST00000578549.5
ENST00000582368.5
AURKB
aurora kinase B
chr17_-_76551174 0.30 ENST00000589145.1
CYGB
cytoglobin
chr2_-_207167220 0.30 ENST00000421199.5
ENST00000457962.5
KLF7
Kruppel like factor 7
chr11_+_125063295 0.30 ENST00000532000.5
ENST00000403796.7
ENST00000308074.4
SLC37A2
solute carrier family 37 member 2
chr6_+_101181254 0.29 ENST00000682090.1
ENST00000421544.6
GRIK2
glutamate ionotropic receptor kainate type subunit 2
chr4_-_25030922 0.28 ENST00000382114.9
LGI2
leucine rich repeat LGI family member 2
chr20_+_142573 0.27 ENST00000382398.4
DEFB126
defensin beta 126
chr2_+_201132872 0.27 ENST00000470178.6
CFLAR
CASP8 and FADD like apoptosis regulator
chr6_+_123803853 0.27 ENST00000368417.6
NKAIN2
sodium/potassium transporting ATPase interacting 2
chr17_-_66220630 0.26 ENST00000585162.1
APOH
apolipoprotein H
chr6_-_53148822 0.26 ENST00000259803.8
GCM1
glial cells missing transcription factor 1
chr9_+_70043840 0.26 ENST00000377182.5
MAMDC2
MAM domain containing 2
chr17_-_42028662 0.26 ENST00000461831.1
ZNF385C
zinc finger protein 385C
chr3_+_124094663 0.26 ENST00000460856.5
ENST00000240874.7
KALRN
kalirin RhoGEF kinase
chr11_-_2301859 0.25 ENST00000456145.2
ENST00000381153.8
C11orf21
chromosome 11 open reading frame 21
chr8_-_92017292 0.25 ENST00000521553.5
RUNX1T1
RUNX1 partner transcriptional co-repressor 1
chr5_-_147906530 0.25 ENST00000318315.5
ENST00000515291.1
C5orf46
chromosome 5 open reading frame 46
chr6_-_87095059 0.24 ENST00000369582.6
ENST00000610310.3
ENST00000630630.2
ENST00000627148.3
ENST00000625577.1
CGA
glycoprotein hormones, alpha polypeptide
chr17_+_39628496 0.24 ENST00000394265.5
ENST00000394267.2
PPP1R1B
protein phosphatase 1 regulatory inhibitor subunit 1B
chr2_+_203867764 0.23 ENST00000648405.2
CTLA4
cytotoxic T-lymphocyte associated protein 4
chr1_-_155934398 0.22 ENST00000368320.7
ENST00000368321.8
KHDC4
KH domain containing 4, pre-mRNA splicing factor
chr12_-_53335737 0.22 ENST00000303846.3
SP7
Sp7 transcription factor
chr6_+_43132472 0.22 ENST00000489707.5
PTK7
protein tyrosine kinase 7 (inactive)
chr11_-_19202004 0.22 ENST00000648719.1
CSRP3
cysteine and glycine rich protein 3
chr16_+_6019585 0.21 ENST00000547372.5
RBFOX1
RNA binding fox-1 homolog 1
chr12_-_53336342 0.21 ENST00000537210.2
ENST00000536324.4
SP7
Sp7 transcription factor
chr11_+_111540659 0.21 ENST00000375615.7
ENST00000525126.5
ENST00000375614.7
ENST00000533265.5
LAYN
layilin
chr19_-_12835400 0.20 ENST00000591512.2
ENST00000587549.1
ENST00000322912.9
RTBDN
retbindin
chr1_-_167914089 0.20 ENST00000476818.2
ENST00000367848.1
ENST00000367851.9
ENST00000545172.5
ADCY10
adenylate cyclase 10
chr9_-_97938157 0.20 ENST00000616898.2
HEMGN
hemogen
chrX_+_150363258 0.20 ENST00000683696.1
MAMLD1
mastermind like domain containing 1
chr19_-_12834548 0.19 ENST00000590404.6
ENST00000592204.5
ENST00000674343.2
RTBDN
retbindin
chr1_+_27392612 0.19 ENST00000374024.4
GPR3
G protein-coupled receptor 3
chr18_+_12308232 0.19 ENST00000590103.5
ENST00000591909.5
ENST00000586653.5
ENST00000317702.10
ENST00000592683.5
ENST00000590967.5
ENST00000591208.1
ENST00000591463.1
TUBB6
tubulin beta 6 class V
chr1_+_11189347 0.19 ENST00000376819.4
ANGPTL7
angiopoietin like 7
chr1_-_101996919 0.19 ENST00000370103.9
OLFM3
olfactomedin 3
chr10_+_103245887 0.18 ENST00000441178.2
RPEL1
ribulose-5-phosphate-3-epimerase like 1
chr9_-_120793377 0.18 ENST00000684001.1
ENST00000684405.1
ENST00000608872.6
FBXW2
F-box and WD repeat domain containing 2
chr19_-_37210484 0.18 ENST00000527838.5
ENST00000591492.5
ENST00000532828.7
ZNF585B
zinc finger protein 585B
chrX_+_150363306 0.18 ENST00000370401.7
ENST00000432680.7
MAMLD1
mastermind like domain containing 1
chr13_-_60013178 0.18 ENST00000498416.2
ENST00000465066.5
DIAPH3
diaphanous related formin 3
chrX_+_15749848 0.18 ENST00000479740.5
ENST00000454127.2
CA5B
carbonic anhydrase 5B
chr11_+_2302119 0.17 ENST00000381121.7
TSPAN32
tetraspanin 32
chr6_+_11093753 0.17 ENST00000416247.4
SMIM13
small integral membrane protein 13
chr1_+_27935022 0.16 ENST00000411604.5
ENST00000373888.8
SMPDL3B
sphingomyelin phosphodiesterase acid like 3B
chr20_+_31368594 0.16 ENST00000253381.3
DEFB118
defensin beta 118
chrX_+_71144818 0.16 ENST00000536169.5
ENST00000358741.4
ENST00000395855.6
ENST00000374051.7
NLGN3
neuroligin 3
chr17_+_6444441 0.16 ENST00000250056.12
ENST00000571373.5
ENST00000570337.6
ENST00000572595.6
ENST00000572447.6
ENST00000576056.5
PIMREG
PICALM interacting mitotic regulator
chr10_+_50990864 0.16 ENST00000401604.8
PRKG1
protein kinase cGMP-dependent 1
chr2_+_201132769 0.15 ENST00000494258.5
CFLAR
CASP8 and FADD like apoptosis regulator
chr1_+_43979179 0.15 ENST00000434555.7
ENST00000372324.6
ENST00000481924.2
B4GALT2
beta-1,4-galactosyltransferase 2
chr17_-_42185452 0.15 ENST00000293330.1
HCRT
hypocretin neuropeptide precursor
chr4_-_103019634 0.15 ENST00000510559.1
ENST00000296422.12
ENST00000394789.7
SLC9B1
solute carrier family 9 member B1
chr17_-_47831509 0.15 ENST00000414011.1
ENST00000351111.7
MRPL10
mitochondrial ribosomal protein L10
chr7_-_142885737 0.14 ENST00000359396.9
ENST00000436401.1
TRPV6
transient receptor potential cation channel subfamily V member 6
chr3_+_141384790 0.14 ENST00000507722.5
ZBTB38
zinc finger and BTB domain containing 38
chr10_+_116590956 0.14 ENST00000358834.9
ENST00000528052.5
PNLIPRP1
pancreatic lipase related protein 1
chr10_+_116591010 0.13 ENST00000530319.5
ENST00000527980.5
ENST00000471549.5
ENST00000534537.5
PNLIPRP1
pancreatic lipase related protein 1
chr17_+_38428456 0.13 ENST00000622683.5
ENST00000620417.4
ARHGAP23
Rho GTPase activating protein 23
chr9_-_120793343 0.13 ENST00000684047.1
FBXW2
F-box and WD repeat domain containing 2
chr2_+_201132928 0.13 ENST00000462763.5
CFLAR
CASP8 and FADD like apoptosis regulator
chr11_-_26722051 0.11 ENST00000396005.8
SLC5A12
solute carrier family 5 member 12
chr12_-_52814106 0.11 ENST00000551956.2
KRT4
keratin 4
chr19_-_12835421 0.11 ENST00000589272.5
RTBDN
retbindin
chr18_-_46756791 0.11 ENST00000538168.5
ENST00000536490.1
ST8SIA5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr7_+_76510516 0.11 ENST00000257632.9
UPK3B
uroplakin 3B
chr14_+_96256194 0.11 ENST00000216629.11
ENST00000553356.1
BDKRB1
bradykinin receptor B1
chr3_-_9769910 0.11 ENST00000256460.8
CAMK1
calcium/calmodulin dependent protein kinase I
chr15_-_31101707 0.10 ENST00000397795.6
ENST00000256552.11
ENST00000559179.2
TRPM1
transient receptor potential cation channel subfamily M member 1
chr2_-_128027273 0.10 ENST00000259235.7
ENST00000357702.9
ENST00000424298.5
SAP130
Sin3A associated protein 130
chr4_+_25160631 0.10 ENST00000510415.1
ENST00000507794.2
ENST00000512921.4
SEPSECS-AS1
PI4K2B
SEPSECS antisense RNA 1 (head to head)
phosphatidylinositol 4-kinase type 2 beta
chr1_+_207089195 0.10 ENST00000452902.6
C4BPB
complement component 4 binding protein beta
chr11_+_2301987 0.09 ENST00000612299.4
ENST00000182290.9
TSPAN32
tetraspanin 32
chr5_+_144205250 0.09 ENST00000507359.3
KCTD16
potassium channel tetramerization domain containing 16
chr5_-_181205182 0.09 ENST00000274773.12
TRIM7
tripartite motif containing 7
chr3_+_148697784 0.09 ENST00000497524.5
ENST00000418473.7
ENST00000349243.8
ENST00000404754.2
AGTR1
angiotensin II receptor type 1
chr18_-_46757012 0.09 ENST00000315087.12
ST8SIA5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr19_+_7920313 0.09 ENST00000221573.11
ENST00000595637.1
SNAPC2
small nuclear RNA activating complex polypeptide 2
chr3_+_124094696 0.09 ENST00000360013.7
ENST00000684186.1
ENST00000684276.1
KALRN
kalirin RhoGEF kinase
chr7_-_81770039 0.08 ENST00000222390.11
ENST00000453411.6
ENST00000457544.7
ENST00000444829.7
HGF
hepatocyte growth factor
chr21_+_33230073 0.08 ENST00000342101.7
ENST00000413881.5
ENST00000443073.5
IFNAR2
interferon alpha and beta receptor subunit 2
chr7_+_97005538 0.08 ENST00000518156.3
DLX6
distal-less homeobox 6
chr1_+_207089233 0.08 ENST00000243611.9
ENST00000367076.7
C4BPB
complement component 4 binding protein beta
chr1_+_45012691 0.08 ENST00000469548.5
UROD
uroporphyrinogen decarboxylase
chr1_+_207089283 0.07 ENST00000391923.1
C4BPB
complement component 4 binding protein beta
chr2_+_201132958 0.07 ENST00000479953.6
ENST00000340870.6
CFLAR
CASP8 and FADD like apoptosis regulator
chr10_+_97584347 0.07 ENST00000370649.3
ENST00000370646.9
ENSG00000249967.1
HOGA1
novel protein
4-hydroxy-2-oxoglutarate aldolase 1
chr1_+_45012896 0.07 ENST00000428106.1
UROD
uroporphyrinogen decarboxylase
chr1_+_207088825 0.06 ENST00000367078.8
C4BPB
complement component 4 binding protein beta
chr19_+_55488404 0.06 ENST00000594321.5
ENST00000389623.11
SSC5D
scavenger receptor cysteine rich family member with 5 domains
chr6_+_44223770 0.05 ENST00000652453.1
ENST00000393841.6
ENST00000371724.6
ENST00000642777.1
ENST00000645692.1
SLC29A1
solute carrier family 29 member 1 (Augustine blood group)
chr12_-_56360084 0.04 ENST00000314128.9
ENST00000557235.5
ENST00000651915.1
STAT2
signal transducer and activator of transcription 2
chr2_-_42361198 0.04 ENST00000234301.3
COX7A2L
cytochrome c oxidase subunit 7A2 like
chr15_-_78811415 0.04 ENST00000388820.5
ADAMTS7
ADAM metallopeptidase with thrombospondin type 1 motif 7
chr20_+_59721210 0.04 ENST00000395636.6
ENST00000361300.4
PHACTR3
phosphatase and actin regulator 3
chr1_+_52404591 0.04 ENST00000257181.10
PRPF38A
pre-mRNA processing factor 38A
chr7_+_112450451 0.03 ENST00000429071.5
ENST00000403825.8
ENST00000675268.1
IFRD1
ENSG00000288634.1
interferon related developmental regulator 1
novel protein
chr14_+_21030509 0.03 ENST00000481535.5
TPPP2
tubulin polymerization promoting protein family member 2
chr12_+_109900258 0.03 ENST00000405876.9
TCHP
trichoplein keratin filament binding
chr12_+_67648737 0.03 ENST00000344096.4
ENST00000393555.3
DYRK2
dual specificity tyrosine phosphorylation regulated kinase 2
chr9_+_122614738 0.02 ENST00000297913.3
OR1Q1
olfactory receptor family 1 subfamily Q member 1
chr3_+_112332500 0.02 ENST00000606471.5
CD200
CD200 molecule
chr11_+_67403887 0.02 ENST00000526387.5
TBC1D10C
TBC1 domain family member 10C
chr10_-_5003850 0.02 ENST00000421196.7
ENST00000455190.2
ENST00000380753.8
AKR1C2
aldo-keto reductase family 1 member C2
chr17_+_7933080 0.02 ENST00000565740.5
CNTROB
centrobin, centriole duplication and spindle assembly protein
chr15_+_68277724 0.02 ENST00000306917.5
FEM1B
fem-1 homolog B
chr3_-_15341368 0.02 ENST00000408919.7
SH3BP5
SH3 domain binding protein 5
chr14_+_73616844 0.02 ENST00000381139.1
ACOT6
acyl-CoA thioesterase 6
chr11_+_67404077 0.02 ENST00000542590.2
ENST00000312390.9
TBC1D10C
TBC1 domain family member 10C
chr5_-_151087131 0.02 ENST00000315050.11
ENST00000523338.5
ENST00000522100.5
TNIP1
TNFAIP3 interacting protein 1
chr9_-_35828579 0.01 ENST00000377984.2
ENST00000423537.7
ENST00000472182.1
FAM221B
family with sequence similarity 221 member B
chr16_+_6019663 0.01 ENST00000422070.8
RBFOX1
RNA binding fox-1 homolog 1
chr7_+_73827737 0.01 ENST00000435050.1
CLDN4
claudin 4
chr10_+_97584314 0.01 ENST00000370647.8
HOGA1
4-hydroxy-2-oxoglutarate aldolase 1
chr7_-_20217342 0.01 ENST00000400331.10
ENST00000332878.8
MACC1
MET transcriptional regulator MACC1
chr16_-_30031259 0.01 ENST00000380495.8
TLCD3B
TLC domain containing 3B
chr16_-_89490479 0.01 ENST00000642600.1
ENST00000301030.10
ANKRD11
ankyrin repeat domain 11
chr7_-_151057848 0.00 ENST00000297518.4
CDK5
cyclin dependent kinase 5
chr9_-_112332962 0.00 ENST00000458258.5
ENST00000210227.4
PTBP3
polypyrimidine tract binding protein 3
chr18_+_7567266 0.00 ENST00000580170.6
PTPRM
protein tyrosine phosphatase receptor type M

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.1 0.9 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.1 0.7 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.1 1.8 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.1 0.7 GO:0015798 myo-inositol transport(GO:0015798)
0.1 0.4 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 0.3 GO:0060018 astrocyte fate commitment(GO:0060018)
0.1 0.5 GO:0019732 antifungal humoral response(GO:0019732)
0.1 0.3 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 0.4 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 0.7 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.1 0.6 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.4 GO:0060492 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.1 0.6 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.7 GO:0070170 enamel mineralization(GO:0070166) regulation of tooth mineralization(GO:0070170)
0.0 0.3 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.0 0.3 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.3 GO:1903027 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.0 0.2 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.7 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.3 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.4 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.3 GO:0060125 habituation(GO:0046959) negative regulation of growth hormone secretion(GO:0060125)
0.0 0.2 GO:0051673 membrane disruption in other organism(GO:0051673)
0.0 0.2 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.3 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.2 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.2 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052) pentose catabolic process(GO:0019323)
0.0 0.1 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 2.6 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.1 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.0 0.3 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.2 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.1 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.1 GO:0042494 detection of bacterial lipoprotein(GO:0042494)
0.0 0.3 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 1.5 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.2 GO:0003351 epithelial cilium movement(GO:0003351)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.6 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.5 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.1 0.3 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.3 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.4 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.4 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 0.6 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.4 GO:1990909 Wnt signalosome(GO:1990909)
0.0 1.0 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.0 0.3 GO:0031089 platelet dense granule lumen(GO:0031089)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0031696 alpha-2C adrenergic receptor binding(GO:0031696)
0.2 0.6 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.1 0.7 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 0.5 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.1 1.8 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 0.5 GO:1902444 riboflavin binding(GO:1902444)
0.1 2.6 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.2 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.1 0.3 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.1 0.4 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1 0.2 GO:0004750 ribulose-phosphate 3-epimerase activity(GO:0004750)
0.1 0.3 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.3 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.2 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.1 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.0 0.3 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.3 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 0.2 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.4 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.4 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.6 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:0004905 type I interferon receptor activity(GO:0004905)
0.0 0.2 GO:0031433 telethonin binding(GO:0031433)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.4 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.7 GO:0050699 WW domain binding(GO:0050699)
0.0 0.3 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.4 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.7 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.9 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.7 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.7 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.7 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.6 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.4 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.5 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.2 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide