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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for HES7_HES5

Z-value: 0.77

Motif logo

Transcription factors associated with HES7_HES5

Gene Symbol Gene ID Gene Info
ENSG00000179111.9 HES7
ENSG00000197921.6 HES5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HES7hg38_v1_chr17_-_8124084_81241140.523.1e-03Click!
HES5hg38_v1_chr1_-_2530256_2530270-0.029.1e-01Click!

Activity profile of HES7_HES5 motif

Sorted Z-values of HES7_HES5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HES7_HES5

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr21_+_41322805 5.00 ENST00000398646.3
FAM3 metabolism regulating signaling molecule B
chr13_+_34942263 4.63 ENST00000379939.7
ENST00000400445.7
neurobeachin
chr7_-_73770258 3.15 ENST00000395145.3
claudin 3
chr9_+_68705414 3.07 ENST00000541509.5
phosphatidylinositol-4-phosphate 5-kinase type 1 beta
chr17_+_41930599 2.43 ENST00000377540.6
outer dynein arm docking complex subunit 4
chr2_+_219253243 2.00 ENST00000490341.3
tubulin alpha 4b
chr1_-_66924791 1.98 ENST00000371023.7
ENST00000371022.3
ENST00000371026.8
dynein axonemal intermediate chain 4
chr11_-_2270584 1.98 ENST00000331289.5
achaete-scute family bHLH transcription factor 2
chr10_+_16436996 1.76 ENST00000535784.7
phosphotriesterase related
chr21_-_44910630 1.76 ENST00000320216.10
ENST00000397852.5
integrin subunit beta 2
chr9_+_89605004 1.65 ENST00000252506.11
ENST00000375769.1
growth arrest and DNA damage inducible gamma
chr17_+_50095331 1.65 ENST00000503176.6
pyruvate dehydrogenase kinase 2
chr20_-_25058115 1.64 ENST00000323482.9
acyl-CoA synthetase short chain family member 1
chr16_+_84175933 1.61 ENST00000569735.1
dynein axonemal assembly factor 1
chr10_+_129467178 1.59 ENST00000306010.8
ENST00000651593.1
O-6-methylguanine-DNA methyltransferase
chr5_-_55233586 1.49 ENST00000282572.5
cyclin O
chr5_+_176810498 1.48 ENST00000509580.2
unc-5 netrin receptor A
chr17_-_5111836 1.48 ENST00000575898.5
zinc finger protein 232
chr5_+_176810552 1.42 ENST00000329542.9
unc-5 netrin receptor A
chr7_+_26152188 1.38 ENST00000056233.4
nuclear factor, erythroid 2 like 3
chr16_-_5065911 1.36 ENST00000472572.8
ENST00000474471.7
chromosome 16 open reading frame 89
chr18_+_50967991 1.34 ENST00000588577.5
elaC ribonuclease Z 1
chr20_-_25058168 1.25 ENST00000432802.6
acyl-CoA synthetase short chain family member 1
chr17_+_50095285 1.22 ENST00000503614.5
pyruvate dehydrogenase kinase 2
chr17_-_17206264 1.17 ENST00000321560.4
phospholipase D family member 6
chr17_+_42289213 1.16 ENST00000677301.1
signal transducer and activator of transcription 5A
chr3_-_126101506 1.16 ENST00000509064.5
ENST00000508835.5
solute carrier family 41 member 3
chr11_+_35662739 1.09 ENST00000299413.7
tripartite motif containing 44
chr11_+_60429595 1.08 ENST00000528905.1
ENST00000528093.1
membrane spanning 4-domains A5
chr1_+_239386942 1.07 ENST00000675184.1
cholinergic receptor muscarinic 3
chr19_+_12995554 1.00 ENST00000397661.6
nuclear factor I X
chr2_+_148644706 0.99 ENST00000258484.11
enhancer of polycomb homolog 2
chr11_-_63608542 0.99 ENST00000540943.1
phospholipase A and acyltransferase 3
chr3_+_48989876 0.98 ENST00000343546.8
prolyl 4-hydroxylase, transmembrane
chr4_-_18021727 0.94 ENST00000675605.1
ENST00000675927.1
ENST00000674942.1
ENST00000675143.1
ENST00000382226.5
ENST00000326877.8
ENST00000635767.1
ligand dependent nuclear receptor corepressor like
chr20_-_2840623 0.92 ENST00000360652.7
ENST00000448755.5
PC-esterase domain containing 1A
chr11_+_60429567 0.90 ENST00000300190.7
membrane spanning 4-domains A5
chr17_-_42194459 0.88 ENST00000593209.5
ENST00000588352.5
ENST00000587427.6
ENST00000414034.7
ENST00000590249.5
ENST00000428494.6
GH3 domain containing
chr17_+_42288429 0.87 ENST00000676631.1
ENST00000677893.1
signal transducer and activator of transcription 5A
chr19_+_42306937 0.84 ENST00000595750.2
proline rich 19
chr11_-_26572102 0.79 ENST00000455601.6
mucin 15, cell surface associated
chr20_+_57391388 0.77 ENST00000356208.10
ENST00000440234.6
RNA binding motif protein 38
chr17_+_42288464 0.76 ENST00000590726.7
ENST00000678903.1
ENST00000590949.6
ENST00000676585.1
ENST00000588868.5
signal transducer and activator of transcription 5A
chr1_+_27934980 0.75 ENST00000373894.8
sphingomyelin phosphodiesterase acid like 3B
chr1_+_44674688 0.74 ENST00000418644.5
ENST00000458657.6
ENST00000535358.6
ENST00000441519.5
ENST00000445071.5
armadillo like helical domain containing 1
chr2_+_27442365 0.70 ENST00000543753.5
ENST00000288873.7
keratinocyte associated protein 3
chr16_+_3500964 0.70 ENST00000574369.5
ENST00000576634.6
ENST00000341633.9
ENST00000571025.5
clusterin associated protein 1
chr10_+_48306698 0.67 ENST00000374179.8
mitogen-activated protein kinase 8
chr3_-_25783434 0.67 ENST00000396649.7
ENST00000280700.10
ENST00000428257.5
N-glycanase 1
chr1_+_27935110 0.66 ENST00000549094.1
sphingomyelin phosphodiesterase acid like 3B
chr2_+_27442421 0.66 ENST00000407293.5
keratinocyte associated protein 3
chr9_-_97633343 0.64 ENST00000341170.5
thiosulfate sulfurtransferase like domain containing 2
chr13_+_114314474 0.62 ENST00000463003.2
ENST00000645174.1
ENST00000361283.4
ENST00000644294.1
chromosome alignment maintaining phosphoprotein 1
chr4_+_127965429 0.61 ENST00000513371.1
ENST00000611882.1
abhydrolase domain containing 18
chr11_+_537517 0.61 ENST00000270115.8
leucine rich repeat containing 56
chr16_+_75222609 0.60 ENST00000495583.1
chymotrypsinogen B1
chr7_+_74209989 0.57 ENST00000361082.7
ENST00000275635.11
ENST00000460943.6
ENST00000470709.1
linker for activation of T cells family member 2
chr4_+_1009954 0.55 ENST00000398484.6
fibroblast growth factor receptor like 1
chr17_-_1628341 0.55 ENST00000571650.5
solute carrier family 43 member 2
chr10_+_48306639 0.55 ENST00000395611.7
ENST00000432379.5
ENST00000374189.5
mitogen-activated protein kinase 8
chr5_+_79236092 0.52 ENST00000396137.5
junction mediating and regulatory protein, p53 cofactor
chr13_-_113208634 0.50 ENST00000375457.2
ENST00000375477.5
ENST00000337344.9
ENST00000246505.9
ENST00000622406.4
ENST00000375479.6
PCI domain containing 2
chr12_-_48924919 0.50 ENST00000444214.6
FKBP prolyl isomerase 11
chr13_-_41194485 0.49 ENST00000379483.4
kelch repeat and BTB domain containing 7
chrX_+_10158448 0.49 ENST00000380829.5
ENST00000421085.7
ENST00000674669.1
ENST00000454850.1
chloride voltage-gated channel 4
chr5_+_149730260 0.48 ENST00000360453.8
ENST00000394320.7
ENST00000309241.10
PPARG coactivator 1 beta
chr11_-_26572130 0.47 ENST00000527569.1
mucin 15, cell surface associated
chr6_+_32637419 0.46 ENST00000374949.2
major histocompatibility complex, class II, DQ alpha 1
chr17_-_7916280 0.46 ENST00000324348.9
ring finger protein 227
chr14_+_65412717 0.45 ENST00000673929.1
fucosyltransferase 8
chr20_-_20712626 0.43 ENST00000202677.12
Ral GTPase activating protein catalytic subunit alpha 2
chr2_-_201739205 0.41 ENST00000681558.1
ENST00000681495.1
alsin Rho guanine nucleotide exchange factor ALS2
chr2_+_10043524 0.40 ENST00000305883.6
Kruppel like factor 11
chr4_-_144019287 0.39 ENST00000638448.1
ENST00000513128.5
ENST00000506516.6
ENST00000429670.3
ENST00000502664.6
glycophorin B (MNS blood group)
chr7_+_23597499 0.39 ENST00000448353.5
coiled-coil domain containing 126
chr17_-_37609361 0.37 ENST00000614941.4
ENST00000619541.4
ENST00000622045.4
ENST00000616179.4
ENST00000621136.4
ENST00000612223.5
ENST00000620424.1
synergin gamma
chr3_+_126394890 0.37 ENST00000352312.6
cilia and flagella associated protein 100
chr7_+_23597373 0.37 ENST00000307471.8
ENST00000409765.5
coiled-coil domain containing 126
chr14_+_65412949 0.36 ENST00000674118.1
ENST00000553924.5
ENST00000358307.6
ENST00000557338.5
ENST00000554610.1
fucosyltransferase 8
chr19_+_12995467 0.36 ENST00000592199.6
nuclear factor I X
chr7_-_72966953 0.35 ENST00000395244.5
tripartite motif containing 74
chr12_+_111766887 0.34 ENST00000416293.7
ENST00000261733.7
aldehyde dehydrogenase 2 family member
chr17_-_7915929 0.34 ENST00000635932.1
ENST00000640240.1
ring finger protein 227
chr8_-_64798725 0.34 ENST00000310193.4
cytochrome P450 family 7 subfamily B member 1
chr11_+_6845683 0.34 ENST00000299454.5
olfactory receptor family 10 subfamily A member 5
chr1_+_166989254 0.34 ENST00000367872.9
ENST00000447624.1
maelstrom spermatogenic transposon silencer
chr10_+_134465 0.33 ENST00000439456.5
ENST00000397962.8
ENST00000309776.8
ENST00000397959.7
zinc finger MYND-type containing 11
chr1_+_239386556 0.33 ENST00000676153.1
cholinergic receptor muscarinic 3
chr11_-_68751441 0.32 ENST00000544963.1
ENST00000443940.6
ENST00000255087.10
testis expressed metallothionein like protein
chr3_-_151384741 0.31 ENST00000302632.4
purinergic receptor P2Y12
chr16_-_29485859 0.31 ENST00000458643.3
nuclear pore complex interacting protein family member B12
chr5_-_115262851 0.31 ENST00000379615.3
ENST00000419445.6
protein geranylgeranyltransferase type I subunit beta
chr1_+_43991588 0.30 ENST00000372318.8
coiled-coil domain containing 24
chr9_-_136304084 0.30 ENST00000638797.2
ENST00000624277.3
coiled-coil domain containing 187
chr17_-_63446260 0.29 ENST00000448884.6
ENST00000582297.5
ENST00000360793.8
ENST00000582034.5
ENST00000578072.1
cytochrome b561
chr19_+_37346283 0.28 ENST00000541583.6
zinc finger protein 875
chr1_+_152686123 0.28 ENST00000368780.4
late cornified envelope 2B
chr16_-_81096163 0.28 ENST00000566566.2
ENST00000569885.6
ENST00000561801.2
ENST00000639689.1
ENST00000638948.1
ENST00000564536.2
ENST00000638192.1
ENST00000640345.1
glycine cleavage system protein H
novel protein
novel protein
chr8_+_17922837 0.28 ENST00000325083.12
pericentriolar material 1
chr8_-_29263063 0.27 ENST00000524189.6
kinesin family member 13B
chr5_+_153490655 0.26 ENST00000518142.5
ENST00000285900.10
glutamate ionotropic receptor AMPA type subunit 1
chr21_+_44012296 0.25 ENST00000291574.9
ENST00000380221.7
trafficking protein particle complex 10
chr16_+_5071806 0.25 ENST00000684335.1
ENST00000684190.1
ENST00000586840.1
ENST00000262374.10
ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase
chr3_+_38496329 0.25 ENST00000287675.10
ENST00000630638.1
ENST00000422077.6
exo/endonuclease G
chr20_-_46363174 0.25 ENST00000372227.5
solute carrier family 35 member C2
chr7_+_74209947 0.24 ENST00000475494.5
ENST00000398475.5
linker for activation of T cells family member 2
chr17_+_47971105 0.24 ENST00000338399.9
ENST00000578018.5
ENST00000579175.5
CDK5 regulatory subunit associated protein 3
chr16_-_4614859 0.23 ENST00000587615.1
ENST00000587649.1
ENST00000590965.1
UBA like domain containing 1
chr10_+_91220603 0.23 ENST00000336126.6
polycomb group ring finger 5
chr16_+_283157 0.23 ENST00000219406.11
ENST00000404312.5
ENST00000456379.1
protein disulfide isomerase family A member 2
chr14_+_105491226 0.23 ENST00000451719.5
ENST00000392523.9
ENST00000392522.7
ENST00000354560.10
ENST00000334656.11
ENST00000450383.1
tubulin epsilon and delta complex 1
chr20_-_18413216 0.23 ENST00000480488.2
double zinc ribbon and ankyrin repeat domains 1
chr2_-_197435002 0.23 ENST00000335508.11
ENST00000414963.2
ENST00000487698.5
splicing factor 3b subunit 1
chr2_+_73984902 0.22 ENST00000409262.8
tet methylcytosine dioxygenase 3
chr16_-_21405319 0.21 ENST00000542817.1
nuclear pore complex interacting protein family member B3
chr7_+_149262165 0.21 ENST00000434415.6
zinc finger family member 783
chr16_-_4614876 0.21 ENST00000591401.5
ENST00000283474.12
ENST00000591897.5
UBA like domain containing 1
chr20_+_36573589 0.21 ENST00000373872.9
ENST00000650844.1
TGFB induced factor homeobox 2
chr16_+_22533600 0.20 ENST00000357370.6
nuclear pore complex interacting protein family member B5
chr3_+_38039199 0.20 ENST00000346219.7
ENST00000308059.11
DLEC1 cilia and flagella associated protein
chr19_+_840991 0.19 ENST00000234347.10
proteinase 3
chr1_+_150282526 0.19 ENST00000447007.5
ENST00000369095.5
ENST00000369094.5
ENST00000290363.6
circadian associated repressor of transcription
chr14_-_50830641 0.19 ENST00000453196.6
ENST00000496749.1
ninein
chr7_+_99616936 0.18 ENST00000394152.7
ENST00000431485.2
zinc finger and SCAN domain containing 25
chr10_-_69409275 0.18 ENST00000373307.5
tachykinin receptor 2
chr15_-_29269750 0.18 ENST00000332303.6
NSE3 homolog, SMC5-SMC6 complex component
chr14_+_65411845 0.18 ENST00000556518.5
ENST00000557164.5
fucosyltransferase 8
chr16_-_21837770 0.17 ENST00000537951.1
nuclear pore complex interacting protein family member B4
chr16_-_30225829 0.17 ENST00000543463.1
nuclear pore complex interacting protein family, member B13
chr14_+_55129242 0.16 ENST00000254301.14
ENST00000554715.1
galectin 3
chr4_+_127965361 0.16 ENST00000444616.5
abhydrolase domain containing 18
chr10_+_4786624 0.15 ENST00000533295.5
aldo-keto reductase family 1 member E2
chr11_+_125904467 0.15 ENST00000263576.11
ENST00000530414.5
ENST00000530129.6
DEAD-box helicase 25
chr19_+_49388243 0.14 ENST00000447857.8
KASH domain containing 5
chr15_-_23039560 0.14 ENST00000615383.5
ENST00000620435.4
tubulin gamma complex associated protein 5
chr6_-_113971120 0.14 ENST00000520895.5
ENST00000521163.5
ENST00000524334.1
ENST00000519065.6
ENST00000368632.6
histone deacetylase 2
chr2_-_2326210 0.13 ENST00000647755.1
myelin transcription factor 1 like
chr7_+_149838365 0.13 ENST00000460379.1
ENST00000223210.5
zinc finger protein 862
chr12_-_90955172 0.13 ENST00000358859.3
coiled-coil glutamate rich protein 1
chr4_-_170003738 0.13 ENST00000502832.1
ENST00000393704.3
microfibril associated protein 3 like
chr7_+_101817601 0.13 ENST00000292535.12
ENST00000546411.7
ENST00000549414.6
ENST00000550008.6
ENST00000556210.1
cut like homeobox 1
chr4_+_93828746 0.12 ENST00000306011.6
atonal bHLH transcription factor 1
chr19_-_52008081 0.12 ENST00000602063.5
ENST00000597747.5
ENST00000594083.5
ENST00000593650.5
ENST00000599631.5
ENST00000598071.6
ENST00000601178.5
ENST00000376716.9
ENST00000391795.7
zinc finger protein 615
chr2_-_231464156 0.12 ENST00000453992.6
ENST00000454824.6
ENST00000417652.6
nucleolin
chr9_-_136764515 0.12 ENST00000316144.6
lipocalin 15
chr15_-_42920638 0.11 ENST00000566931.1
ENST00000564431.5
ENST00000567274.5
ENST00000267890.11
tau tubulin kinase 2
chr15_+_68578970 0.10 ENST00000261861.10
coronin 2B
chr3_+_138434609 0.10 ENST00000389567.9
ENST00000289135.4
extended synaptotagmin 3
chr2_-_287687 0.10 ENST00000401489.6
ENST00000619265.4
ALK and LTK ligand 2
chr9_+_128787331 0.10 ENST00000223865.8
TBC1 domain family member 13
chr2_-_2326378 0.10 ENST00000647618.1
myelin transcription factor 1 like
chr11_-_69675305 0.09 ENST00000535657.5
ENST00000539414.5
ENST00000536870.5
ENST00000538554.6
ENST00000279147.9
LTO1 maturation factor of ABCE1
chr16_+_83968244 0.09 ENST00000305202.9
N-terminal EF-hand calcium binding protein 2
chr9_+_128787243 0.09 ENST00000372648.10
TBC1 domain family member 13
chrX_-_153470555 0.09 ENST00000370211.10
ENST00000330912.7
ENST00000334497.7
ENST00000338525.7
ENST00000370232.4
HAUS augmin like complex subunit 7
three prime repair exonuclease 2
chr19_+_57584131 0.09 ENST00000536878.6
ENST00000597219.1
ENST00000598689.1
ENST00000597850.2
zinc finger protein interacting with K protein 1
chr17_-_46979240 0.08 ENST00000322329.5
reprimo like
chr1_+_160796070 0.08 ENST00000368037.9
lymphocyte antigen 9
chr1_+_160796098 0.08 ENST00000392203.8
lymphocyte antigen 9
chr19_+_4304588 0.08 ENST00000221856.11
fibronectin type III and SPRY domain containing 1
chr2_-_231464475 0.08 ENST00000322723.9
ENST00000678828.1
ENST00000679348.1
ENST00000678246.1
ENST00000678364.1
ENST00000676690.1
nucleolin
chr8_+_103021027 0.07 ENST00000518857.5
ENST00000395862.7
ENST00000518738.2
ENST00000521514.5
ATPase H+ transporting V1 subunit C1
chr17_-_64006880 0.07 ENST00000449662.6
intercellular adhesion molecule 2
chr16_-_23149378 0.07 ENST00000219689.12
ubiquitin specific peptidase 31
chr16_-_48385397 0.06 ENST00000394725.3
siah E3 ubiquitin protein ligase 1
chr1_+_226063466 0.06 ENST00000666609.1
ENST00000661429.1
H3.3 histone A
chr15_-_22980334 0.06 ENST00000610365.4
ENST00000617928.5
ENST00000611832.4
cytoplasmic FMR1 interacting protein 1
chr20_-_47356721 0.05 ENST00000262975.8
ENST00000446994.6
ENST00000355972.8
ENST00000396281.8
ENST00000619049.4
ENST00000611941.4
ENST00000372023.7
zinc finger MYND-type containing 8
chr6_+_122610391 0.05 ENST00000368452.7
cAMP-dependent protein kinase inhibitor beta
chr11_-_69675367 0.05 ENST00000542341.1
LTO1 maturation factor of ABCE1
chr7_+_44748832 0.05 ENST00000309315.9
ENST00000457123.5
zinc finger MIZ-type containing 2
chr16_+_88382950 0.05 ENST00000565624.3
zinc finger protein 469
chr2_-_288056 0.04 ENST00000403610.9
ALK and LTK ligand 2
chr17_-_49414871 0.04 ENST00000504124.6
ENST00000300408.8
ENST00000614445.5
prohibitin
chrX_-_16869840 0.04 ENST00000380084.8
RB binding protein 7, chromatin remodeling factor
chr1_+_1232214 0.04 ENST00000379198.5
beta-1,3-galactosyltransferase 6
chr17_-_49414802 0.03 ENST00000511832.6
ENST00000419140.7
ENST00000617874.5
prohibitin
chr1_+_45688165 0.03 ENST00000372025.5
transmembrane protein 69
chrX_+_106726663 0.03 ENST00000255499.3
ring finger protein 128
chr9_-_132669969 0.02 ENST00000438527.7
DEAD-box helicase 31
chr12_+_57488059 0.02 ENST00000628866.2
ENST00000262027.10
methionyl-tRNA synthetase 1
chr15_-_65185299 0.02 ENST00000300107.7
caseinolytic mitochondrial matrix peptidase chaperone subunit X
chr10_+_116324440 0.02 ENST00000333254.4
coiled-coil domain containing 172
chr2_-_2326161 0.02 ENST00000649810.1
ENST00000648318.1
myelin transcription factor 1 like
chr4_-_127965204 0.02 ENST00000513559.6
ENST00000641186.1
ENST00000641393.1
major facilitator superfamily domain containing 8
chr17_-_44830774 0.02 ENST00000590758.3
ENST00000591424.5
gap junction protein gamma 1
chr1_+_150321523 0.02 ENST00000324862.7
pre-mRNA processing factor 3
chr7_-_1459461 0.02 ENST00000297508.8
MICAL like 2
chr11_+_45922640 0.01 ENST00000401752.6
ENST00000325468.9
LARGE xylosyl- and glucuronyltransferase 2
chr21_+_44353633 0.00 ENST00000397932.6
ENST00000300481.13
transient receptor potential cation channel subfamily M member 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0019427 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate biosynthetic process(GO:0019542)
0.5 2.0 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.4 1.3 GO:0042779 tRNA 3'-trailer cleavage, endonucleolytic(GO:0034414) tRNA 3'-trailer cleavage(GO:0042779)
0.4 1.2 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.4 2.8 GO:0000255 allantoin metabolic process(GO:0000255)
0.4 1.2 GO:0007315 oocyte construction(GO:0007308) oocyte axis specification(GO:0007309) oocyte anterior/posterior axis specification(GO:0007314) pole plasm assembly(GO:0007315) maternal determination of anterior/posterior axis, embryo(GO:0008358) P granule organization(GO:0030719)
0.4 1.5 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.3 1.0 GO:0036071 N-glycan fucosylation(GO:0036071)
0.3 2.9 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.2 1.6 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.2 1.4 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.2 2.9 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 1.6 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 0.5 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 1.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 3.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.5 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
0.1 0.4 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.1 0.2 GO:0044725 chromatin reprogramming in the zygote(GO:0044725)
0.1 1.8 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 1.7 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.1 0.3 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.3 GO:1904124 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.1 0.3 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.2 GO:0033685 negative regulation of luteinizing hormone secretion(GO:0033685)
0.0 0.1 GO:0042668 auditory receptor cell fate determination(GO:0042668)
0.0 0.6 GO:0035372 protein localization to microtubule(GO:0035372) attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.5 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.3 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.1 GO:0070378 positive regulation of ERK5 cascade(GO:0070378)
0.0 0.7 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.2 GO:2000521 negative regulation of immunological synapse formation(GO:2000521)
0.0 0.2 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.0 0.3 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.2 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.3 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.1 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.0 0.3 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.2 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.4 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.6 GO:0060539 diaphragm development(GO:0060539)
0.0 0.1 GO:1904021 negative regulation of G-protein coupled receptor internalization(GO:1904021)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.2 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.6 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.1 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
0.0 0.1 GO:2000259 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.0 0.3 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.1 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 2.8 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 1.3 GO:0016266 O-glycan processing(GO:0016266)
0.0 5.0 GO:0030073 insulin secretion(GO:0030073)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 1.0 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.0 0.2 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.8 GO:0043303 mast cell activation involved in immune response(GO:0002279) mast cell degranulation(GO:0043303)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.9 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.2 1.8 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.2 1.4 GO:0032279 asymmetric synapse(GO:0032279)
0.1 2.8 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 1.0 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.4 GO:0097545 axonemal outer doublet(GO:0097545)
0.1 0.3 GO:0030849 autosome(GO:0030849)
0.1 0.3 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.1 3.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.3 GO:0005960 glycine cleavage complex(GO:0005960)
0.1 2.9 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.4 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:0044308 axonal spine(GO:0044308)
0.0 0.5 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.2 GO:0001940 male pronucleus(GO:0001940)
0.0 0.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.8 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.0 0.5 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 4.1 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.3 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.7 GO:0097542 ciliary tip(GO:0097542)
0.0 0.1 GO:0033391 chromatoid body(GO:0033391)
0.0 0.3 GO:0000242 pericentriolar material(GO:0000242)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.7 2.9 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.5 2.9 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.4 1.3 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.3 1.0 GO:0046921 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.3 1.2 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.2 1.6 GO:0008172 S-methyltransferase activity(GO:0008172) DNA-methyltransferase activity(GO:0009008)
0.2 1.8 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.2 1.4 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 1.5 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.1 1.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.8 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.3 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.1 0.3 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.1 0.3 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.1 0.2 GO:0016497 substance K receptor activity(GO:0016497)
0.1 0.5 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0050571 1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.0 0.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 2.0 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.6 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.5 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.3 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0031687 A2A adenosine receptor binding(GO:0031687)
0.0 2.2 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0030298 receptor signaling protein tyrosine kinase activator activity(GO:0030298)
0.0 0.2 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.3 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.2 GO:0019863 IgE binding(GO:0019863)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.5 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 5.0 GO:0005125 cytokine activity(GO:0005125)
0.0 0.1 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.2 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 1.0 GO:0004402 histone acetyltransferase activity(GO:0004402)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 PID IL5 PATHWAY IL5-mediated signaling events
0.1 3.1 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 2.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 1.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 2.4 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.8 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.8 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.2 2.9 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.2 2.9 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 2.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 1.5 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 3.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 2.8 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 1.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 1.0 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 1.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.5 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 1.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix