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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for HINFP1

Z-value: 0.27

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Transcription factors associated with HINFP1

Gene Symbol Gene ID Gene Info

Activity profile of HINFP1 motif

Sorted Z-values of HINFP1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HINFP1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr5_+_155013755 0.67 ENST00000435029.6
KIF4B
kinesin family member 4B
chr2_-_233854566 0.67 ENST00000432087.5
ENST00000441687.5
ENST00000414924.5
HJURP
Holliday junction recognition protein
chr9_-_91423819 0.61 ENST00000297689.4
NFIL3
nuclear factor, interleukin 3 regulated
chr2_-_233854506 0.56 ENST00000411486.7
HJURP
Holliday junction recognition protein
chr18_+_12308232 0.49 ENST00000590103.5
ENST00000591909.5
ENST00000586653.5
ENST00000317702.10
ENST00000592683.5
ENST00000590967.5
ENST00000591208.1
ENST00000591463.1
TUBB6
tubulin beta 6 class V
chr16_+_560388 0.33 ENST00000409413.4
PRR35
proline rich 35
chr2_-_130181542 0.32 ENST00000441135.1
ENST00000680679.1
ENST00000680401.1
ENST00000351288.10
ENST00000680298.1
ENST00000431183.6
SMPD4
sphingomyelin phosphodiesterase 4
chr20_+_37346128 0.31 ENST00000373578.7
SRC
SRC proto-oncogene, non-receptor tyrosine kinase
chr10_+_119818699 0.29 ENST00000650409.1
INPP5F
inositol polyphosphate-5-phosphatase F
chr12_-_120265719 0.24 ENST00000637617.2
ENST00000267257.11
ENST00000228307.11
ENST00000424649.6
PXN
paxillin
chr2_+_130181662 0.22 ENST00000425361.5
ENST00000457492.5
MZT2B
mitotic spindle organizing protein 2B
chr2_+_130182224 0.21 ENST00000651060.1
ENST00000409255.1
ENST00000281871.11
ENST00000455239.1
MZT2B
mitotic spindle organizing protein 2B
chr3_+_133574434 0.21 ENST00000508481.5
ENST00000420115.6
ENST00000504867.5
ENST00000507408.5
ENST00000511392.5
ENST00000515421.1
CDV3
CDV3 homolog
chr3_+_133573915 0.20 ENST00000431519.6
CDV3
CDV3 homolog
chr18_+_11981548 0.19 ENST00000588927.5
IMPA2
inositol monophosphatase 2
chr18_+_11981488 0.18 ENST00000269159.8
IMPA2
inositol monophosphatase 2
chr21_+_34073569 0.18 ENST00000399312.3
ENST00000381151.5
ENST00000362077.4
MRPS6
SLC5A3
ENSG00000272657.1
mitochondrial ribosomal protein S6
solute carrier family 5 member 3
novel transcript
chr3_+_133574007 0.18 ENST00000503932.5
CDV3
CDV3 homolog
chr1_+_209938207 0.18 ENST00000472886.5
SYT14
synaptotagmin 14
chr1_-_42766978 0.16 ENST00000372526.2
ENST00000236040.8
ENST00000296388.10
ENST00000397054.7
P3H1
prolyl 3-hydroxylase 1
chr1_+_209938169 0.15 ENST00000367019.5
ENST00000537238.5
ENST00000637265.1
SYT14
synaptotagmin 14
chrX_-_126552801 0.14 ENST00000371126.3
DCAF12L1
DDB1 and CUL4 associated factor 12 like 1
chr10_+_110644306 0.13 ENST00000369519.4
RBM20
RNA binding motif protein 20
chr15_+_84981981 0.11 ENST00000339708.9
PDE8A
phosphodiesterase 8A
chr1_-_62319264 0.11 ENST00000354381.3
KANK4
KN motif and ankyrin repeat domains 4
chr10_-_95693893 0.10 ENST00000371209.5
ENST00000680144.1
ENST00000430368.6
ENST00000371217.10
TCTN3
tectonic family member 3
chr10_-_931624 0.09 ENST00000406525.6
LARP4B
La ribonucleoprotein 4B
chr10_-_95693936 0.08 ENST00000680709.1
ENST00000680353.1
ENST00000679566.1
ENST00000614499.5
TCTN3
tectonic family member 3
chr10_+_48306639 0.06 ENST00000395611.7
ENST00000432379.5
ENST00000374189.5
MAPK8
mitogen-activated protein kinase 8
chr14_+_73237493 0.06 ENST00000340738.9
ENST00000644200.2
PAPLN
papilin, proteoglycan like sulfated glycoprotein
chr6_-_144095556 0.05 ENST00000367569.4
SF3B5
splicing factor 3b subunit 5
chr15_+_84981834 0.05 ENST00000394553.6
PDE8A
phosphodiesterase 8A
chr10_+_48306698 0.05 ENST00000374179.8
MAPK8
mitogen-activated protein kinase 8
chr15_-_58065734 0.05 ENST00000347587.7
ALDH1A2
aldehyde dehydrogenase 1 family member A2
chr15_-_58065703 0.05 ENST00000249750.9
ALDH1A2
aldehyde dehydrogenase 1 family member A2
chr1_-_62319425 0.05 ENST00000371153.9
KANK4
KN motif and ankyrin repeat domains 4
chr15_-_58065870 0.04 ENST00000537372.5
ALDH1A2
aldehyde dehydrogenase 1 family member A2
chr8_-_41896713 0.03 ENST00000265709.13
ANK1
ankyrin 1
chr10_+_131900999 0.03 ENST00000455566.6
PPP2R2D
protein phosphatase 2 regulatory subunit Bdelta
chr1_+_222713310 0.03 ENST00000537020.5
ENST00000539697.5
BROX
BRO1 domain and CAAX motif containing
chr10_-_931684 0.03 ENST00000316157.8
LARP4B
La ribonucleoprotein 4B
chr7_-_1569955 0.02 ENST00000288607.3
ENST00000404674.7
PSMG3
proteasome assembly chaperone 3
chr19_-_5680488 0.01 ENST00000587589.1
ENST00000309324.9
MICOS13
mitochondrial contact site and cristae organizing system subunit 13
chr19_+_1524068 0.00 ENST00000642079.2
ENST00000454744.7
ENST00000588430.3
PLK5
polo like kinase 5 (inactive)

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.1 0.4 GO:0006021 inositol biosynthetic process(GO:0006021)
0.1 0.3 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.1 0.2 GO:1901874 negative regulation of post-translational protein modification(GO:1901874)
0.0 0.7 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.1 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.0 1.2 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.2 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.6 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 0.2 GO:0007172 signal complex assembly(GO:0007172)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0052832 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.2 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.0 0.3 GO:0071253 connexin binding(GO:0071253)
0.0 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 ST STAT3 PATHWAY STAT3 Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.0 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway