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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for HIVEP1

Z-value: 0.75

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Transcription factors associated with HIVEP1

Gene Symbol Gene ID Gene Info
ENSG00000095951.17 HIVEP1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HIVEP1hg38_v1_chr6_+_12012304_12012338-0.086.7e-01Click!

Activity profile of HIVEP1 motif

Sorted Z-values of HIVEP1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HIVEP1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr6_+_32439866 3.90 ENST00000374982.5
ENST00000395388.7
major histocompatibility complex, class II, DR alpha
chr5_-_150412743 3.46 ENST00000353334.11
ENST00000009530.12
ENST00000377795.7
CD74 molecule
chr12_-_62935117 2.50 ENST00000228705.7
protein phosphatase, Mg2+/Mn2+ dependent 1H
chr10_-_13099652 2.47 ENST00000378839.1
coiled-coil domain containing 3
chr9_-_110208156 1.99 ENST00000400613.5
chromosome 9 open reading frame 152
chr6_+_32741382 1.94 ENST00000374940.4
major histocompatibility complex, class II, DQ alpha 2
chr11_+_27040725 1.74 ENST00000529202.5
ENST00000263182.8
gamma-butyrobetaine hydroxylase 1
chr17_+_42288464 1.32 ENST00000590726.7
ENST00000678903.1
ENST00000590949.6
ENST00000676585.1
ENST00000588868.5
signal transducer and activator of transcription 5A
chr17_+_42288429 1.30 ENST00000676631.1
ENST00000677893.1
signal transducer and activator of transcription 5A
chr14_+_77181780 1.25 ENST00000298351.5
ENST00000554346.5
transmembrane protein 63C
chr14_+_75522427 1.24 ENST00000286639.8
basic leucine zipper ATF-like transcription factor
chr6_-_32941018 1.12 ENST00000418107.3
major histocompatibility complex, class II, DM beta
chr11_+_827913 1.12 ENST00000525077.2
calcium release activated channel regulator 2B
chr14_+_75522531 1.01 ENST00000555504.1
basic leucine zipper ATF-like transcription factor
chr6_+_32637419 1.01 ENST00000374949.2
major histocompatibility complex, class II, DQ alpha 1
chr10_+_12349685 0.99 ENST00000378845.5
calcium/calmodulin dependent protein kinase ID
chr7_-_120858066 0.99 ENST00000222747.8
tetraspanin 12
chr8_-_100309368 0.96 ENST00000523167.1
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr1_+_212565334 0.95 ENST00000366981.8
ENST00000366987.6
activating transcription factor 3
chr2_+_96816236 0.90 ENST00000377060.7
ENST00000305510.4
cyclin and CBS domain divalent metal cation transport mediator 3
chr19_+_45001430 0.90 ENST00000625761.2
ENST00000505236.1
ENST00000221452.13
RELB proto-oncogene, NF-kB subunit
chr11_+_828150 0.89 ENST00000450448.5
calcium release activated channel regulator 2B
chr10_+_94089067 0.89 ENST00000371375.1
ENST00000675218.1
phospholipase C epsilon 1
chr10_+_94089034 0.89 ENST00000676102.1
ENST00000371385.8
phospholipase C epsilon 1
chr9_-_32526185 0.88 ENST00000379883.3
ENST00000379868.6
ENST00000679859.1
DExD/H-box helicase 58
chr10_+_112374110 0.88 ENST00000354655.9
acyl-CoA synthetase long chain family member 5
chr7_-_120858303 0.86 ENST00000415871.5
ENST00000430985.1
tetraspanin 12
chr11_+_827545 0.85 ENST00000528542.6
calcium release activated channel regulator 2B
chr15_-_72197772 0.82 ENST00000309731.12
GRAM domain containing 2A
chr5_-_16508788 0.77 ENST00000682142.1
reticulophagy regulator 1
chr5_-_16508990 0.75 ENST00000399793.6
reticulophagy regulator 1
chr6_-_31357171 0.75 ENST00000412585.7
ENST00000434333.1
major histocompatibility complex, class I, B
chr10_+_93993897 0.73 ENST00000371380.8
phospholipase C epsilon 1
chr16_+_3065297 0.70 ENST00000325568.9
interleukin 32
chr19_+_55836532 0.69 ENST00000301295.11
NLR family pyrin domain containing 4
chr7_+_24285107 0.68 ENST00000405982.1
neuropeptide Y
chr15_-_41230697 0.67 ENST00000314992.9
ENST00000558396.1
ENST00000458580.7
exonuclease 3'-5' domain containing 1
chr17_-_1628808 0.65 ENST00000301335.10
solute carrier family 43 member 2
chr3_-_146251136 0.64 ENST00000493382.5
ENST00000383083.6
phospholipid scramblase 4
chr11_-_75351609 0.64 ENST00000420843.7
arrestin beta 1
chr16_+_57358775 0.63 ENST00000219235.5
C-C motif chemokine ligand 22
chr6_+_29723421 0.63 ENST00000259951.12
ENST00000434407.6
major histocompatibility complex, class I, F
chr17_-_43907467 0.63 ENST00000520406.5
ENST00000518478.1
ENST00000522172.5
ENST00000461854.5
ENST00000521178.5
ENST00000269095.9
ENST00000520305.5
ENST00000523501.5
ENST00000520241.5
membrane palmitoylated protein 2
chr6_+_29723340 0.63 ENST00000334668.8
major histocompatibility complex, class I, F
chr17_-_58527980 0.63 ENST00000583114.5
septin 4
chr1_-_160031946 0.62 ENST00000368090.5
phosphatidylinositol glycan anchor biosynthesis class M
chr3_-_58211212 0.62 ENST00000461914.7
deoxyribonuclease 1 like 3
chr1_+_46175079 0.62 ENST00000372003.6
tetraspanin 1
chr16_+_2475051 0.61 ENST00000567020.6
ENST00000646147.1
TBC1 domain family member 24
chr20_-_3173516 0.61 ENST00000360342.7
ENST00000645462.1
ENST00000337576.7
leucine zipper tumor suppressor family member 3
chr16_-_66925526 0.61 ENST00000299759.11
ENST00000420652.5
RRAD, Ras related glycolysis inhibitor and calcium channel regulator
chr3_-_146251068 0.60 ENST00000433593.6
ENST00000476202.5
ENST00000354952.7
ENST00000460885.5
phospholipid scramblase 4
chr4_+_73836667 0.59 ENST00000226317.10
C-X-C motif chemokine ligand 6
chr16_-_19884828 0.59 ENST00000300571.7
ENST00000570142.5
ENST00000562469.5
G protein-coupled receptor class C group 5 member B
chr17_-_64020544 0.58 ENST00000583366.5
intercellular adhesion molecule 2
chr22_-_37984534 0.56 ENST00000396884.8
SRY-box transcription factor 10
chr6_+_29942523 0.56 ENST00000376809.10
ENST00000376802.2
ENST00000638375.1
major histocompatibility complex, class I, A
chr6_-_44265541 0.56 ENST00000619360.6
NFKB inhibitor epsilon
chr20_+_2295994 0.54 ENST00000381458.6
transglutaminase 3
chr21_-_41953997 0.54 ENST00000380486.4
C2 calcium dependent domain containing 2
chr19_-_55370455 0.53 ENST00000264563.7
ENST00000585513.1
ENST00000590625.5
interleukin 11
chr7_+_107470050 0.53 ENST00000304402.6
G protein-coupled receptor 22
chr12_+_50057548 0.53 ENST00000228468.8
ENST00000447966.7
acid sensing ion channel subunit 1
chr2_-_96505345 0.53 ENST00000310865.7
ENST00000451794.6
neuralized E3 ubiquitin protein ligase 3
chr5_+_54455661 0.53 ENST00000302005.3
heat shock protein family B (small) member 3
chr9_-_37465402 0.53 ENST00000307750.5
zinc finger and BTB domain containing 5
chr14_-_106470788 0.52 ENST00000434710.1
immunoglobulin heavy variable 3-43
chr6_-_31272069 0.51 ENST00000415537.1
ENST00000376228.9
ENST00000383329.7
major histocompatibility complex, class I, C
chr11_+_46295126 0.49 ENST00000534787.1
cAMP responsive element binding protein 3 like 1
chr5_+_161685748 0.49 ENST00000523217.5
gamma-aminobutyric acid type A receptor subunit alpha6
chr5_+_161685708 0.49 ENST00000274545.10
gamma-aminobutyric acid type A receptor subunit alpha6
chr6_+_137867241 0.49 ENST00000612899.5
ENST00000420009.5
TNF alpha induced protein 3
chr2_+_222424520 0.48 ENST00000321276.8
sphingosine-1-phosphate phosphatase 2
chr16_-_1793719 0.48 ENST00000415638.3
insulin like growth factor binding protein acid labile subunit
chr17_+_74274241 0.47 ENST00000582036.5
dynein axonemal intermediate chain 2
chr5_+_10564064 0.46 ENST00000296657.7
ankyrin repeat domain 33B
chr14_+_103123452 0.45 ENST00000558056.1
ENST00000560869.6
TNF alpha induced protein 2
chr17_+_74274229 0.45 ENST00000311014.11
dynein axonemal intermediate chain 2
chr6_+_137867414 0.45 ENST00000237289.8
ENST00000433680.1
TNF alpha induced protein 3
chr1_+_202010575 0.45 ENST00000367283.7
ENST00000367284.10
E74 like ETS transcription factor 3
chr2_+_10043524 0.45 ENST00000305883.6
Kruppel like factor 11
chr8_-_69834970 0.44 ENST00000260126.9
solute carrier organic anion transporter family member 5A1
chr9_+_129665603 0.44 ENST00000372469.6
paired related homeobox 2
chr7_-_127392310 0.44 ENST00000393312.5
zinc finger protein 800
chr10_-_91909476 0.43 ENST00000311575.6
fibroblast growth factor binding protein 3
chr11_-_17389323 0.43 ENST00000528731.1
potassium inwardly rectifying channel subfamily J member 11
chr17_+_59331633 0.42 ENST00000312655.9
yippee like 2
chr19_-_51630401 0.41 ENST00000683636.1
sialic acid binding Ig like lectin 5
chr11_-_5249836 0.41 ENST00000632727.1
ENST00000330597.5
hemoglobin subunit gamma 1
chr12_+_2053545 0.41 ENST00000682336.1
ENST00000344100.7
ENST00000399591.5
ENST00000399595.5
ENST00000399597.5
ENST00000399601.5
ENST00000399606.5
ENST00000399621.5
ENST00000399629.5
ENST00000399637.5
ENST00000399638.5
ENST00000399644.5
ENST00000399649.5
ENST00000402845.7
ENST00000682686.1
calcium voltage-gated channel subunit alpha1 C
chr6_+_32637396 0.40 ENST00000395363.5
ENST00000496318.5
ENST00000343139.11
major histocompatibility complex, class II, DQ alpha 1
chr3_-_13073408 0.40 ENST00000613206.2
IQ motif and Sec7 domain ArfGEF 1
chr10_+_115093404 0.40 ENST00000527407.5
attractin like 1
chr17_-_74712911 0.40 ENST00000326165.11
ENST00000583937.5
ENST00000301573.13
ENST00000469092.5
CD300 molecule like family member f
chr4_-_73998669 0.39 ENST00000296027.5
C-X-C motif chemokine ligand 5
chr12_-_113335030 0.39 ENST00000552014.5
ENST00000680972.1
ENST00000548186.5
ENST00000202831.7
ENST00000549181.5
solute carrier family 8 member B1
chr16_-_53703810 0.39 ENST00000569716.1
ENST00000562588.5
ENST00000621565.5
ENST00000562230.5
ENST00000563746.5
ENST00000568653.7
ENST00000647211.2
RPGRIP1 like
chr1_-_235649734 0.39 ENST00000391854.7
G protein subunit gamma 4
chr12_-_54981838 0.39 ENST00000316577.12
thymocyte expressed, positive selection associated 1
chr19_-_37207074 0.38 ENST00000588873.1
novel protein
chr22_+_36860973 0.38 ENST00000447071.5
ENST00000397147.7
ENST00000248899.11
neutrophil cytosolic factor 4
chr2_-_162318475 0.38 ENST00000648433.1
interferon induced with helicase C domain 1
chr1_+_160127672 0.38 ENST00000447527.1
ATPase Na+/K+ transporting subunit alpha 2
chr16_-_53703883 0.38 ENST00000262135.9
ENST00000564374.5
ENST00000566096.5
RPGRIP1 like
chr12_-_54588516 0.38 ENST00000547431.5
protein phosphatase 1 regulatory inhibitor subunit 1A
chr5_+_142771119 0.38 ENST00000642734.1
Rho GTPase activating protein 26
chr4_-_82798735 0.38 ENST00000273908.4
ENST00000319540.9
stearoyl-CoA desaturase 5
chr12_+_6946468 0.37 ENST00000543115.5
ENST00000399448.5
protein tyrosine phosphatase non-receptor type 6
chr6_+_135181268 0.37 ENST00000341911.10
ENST00000442647.7
ENST00000618728.4
ENST00000316528.12
ENST00000616088.4
MYB proto-oncogene, transcription factor
chr6_-_43510686 0.37 ENST00000372441.1
leucine rich repeat containing 73
chr1_-_155188351 0.37 ENST00000462317.5
mucin 1, cell surface associated
chr6_-_46652786 0.37 ENST00000275016.3
ENST00000619708.4
cytochrome P450 family 39 subfamily A member 1
chr19_+_10430786 0.36 ENST00000293683.9
phosphodiesterase 4A
chr14_-_92040027 0.36 ENST00000267622.8
thyroid hormone receptor interactor 11
chr4_-_74099187 0.36 ENST00000508487.3
C-X-C motif chemokine ligand 2
chr3_+_187368367 0.36 ENST00000259030.3
receptor transporter protein 4
chr11_-_75351686 0.35 ENST00000360025.7
arrestin beta 1
chr7_-_132576463 0.35 ENST00000423507.6
plexin A4
chr5_+_170105892 0.34 ENST00000306268.8
ENST00000449804.4
forkhead box I1
chr19_+_44809053 0.34 ENST00000611077.5
basal cell adhesion molecule (Lutheran blood group)
chr16_-_55875358 0.34 ENST00000319165.13
ENST00000290567.14
carboxylesterase 5A
chr8_-_17676484 0.34 ENST00000634613.1
ENST00000519066.5
microtubule associated scaffold protein 1
chr6_-_111483700 0.34 ENST00000435970.5
ENST00000358835.7
REV3 like, DNA directed polymerase zeta catalytic subunit
chr7_+_24284181 0.34 ENST00000407573.5
ENST00000242152.7
neuropeptide Y
chr11_+_66480425 0.34 ENST00000541961.5
ENST00000532019.5
ENST00000526515.5
ENST00000530165.5
ENST00000533725.5
dipeptidyl peptidase 3
chr22_+_35066136 0.33 ENST00000308700.6
ENST00000404699.7
intestine specific homeobox
chr19_+_17305801 0.33 ENST00000602206.1
ENST00000252602.2
mitochondrial ribosomal protein L34
chr10_+_19816228 0.33 ENST00000377242.7
plexin domain containing 2
chr3_+_119597874 0.33 ENST00000488919.5
ENST00000273371.9
ENST00000495992.5
phospholipase A1 member A
chr5_+_141199555 0.33 ENST00000624887.1
ENST00000354757.5
protocadherin beta 11
chr11_+_65525067 0.33 ENST00000525364.5
ENST00000270176.10
ENST00000420247.6
ENST00000533862.5
ENST00000524944.5
SCY1 like pseudokinase 1
chr2_-_219387881 0.33 ENST00000322176.11
ENST00000273075.9
aspartyl aminopeptidase
chr3_-_187737943 0.33 ENST00000438077.1
BCL6 transcription repressor
chr17_-_76240289 0.33 ENST00000647930.1
ENST00000592271.1
ENST00000319945.10
ring finger protein 157
chr18_-_55321640 0.32 ENST00000637169.2
transcription factor 4
chr1_+_14945775 0.32 ENST00000400797.3
kazrin, periplakin interacting protein
chr14_-_88554898 0.31 ENST00000556564.6
protein tyrosine phosphatase non-receptor type 21
chr12_+_112013418 0.31 ENST00000261735.4
ENST00000552052.1
endoplasmic reticulum protein 29
chr5_+_50666612 0.31 ENST00000281631.10
poly(ADP-ribose) polymerase family member 8
chr17_-_64505357 0.31 ENST00000583212.2
ENST00000578190.5
ENST00000579091.5
ENST00000583239.6
DEAD-box helicase 5
chr11_+_64284982 0.31 ENST00000539833.5
G protein-coupled receptor 137
chr7_+_101817601 0.31 ENST00000292535.12
ENST00000546411.7
ENST00000549414.6
ENST00000550008.6
ENST00000556210.1
cut like homeobox 1
chr19_-_40218339 0.31 ENST00000311308.6
tetratricopeptide repeat domain 9B
chr17_+_7015035 0.31 ENST00000552775.1
chromosome 17 open reading frame 49
chr12_+_112013348 0.31 ENST00000455836.1
endoplasmic reticulum protein 29
chr1_+_37793787 0.31 ENST00000373045.11
mannosidase endo-alpha like
chr17_-_69150062 0.31 ENST00000522787.5
ENST00000521538.5
ATP binding cassette subfamily A member 10
chr5_-_16508858 0.31 ENST00000684456.1
reticulophagy regulator 1
chr6_+_87590067 0.31 ENST00000546266.5
ENST00000257789.4
ENST00000392844.8
origin recognition complex subunit 3
chr14_+_22304051 0.30 ENST00000390466.1
T cell receptor alpha variable 39
chr14_-_35404650 0.30 ENST00000553342.1
ENST00000557140.5
ENST00000216797.10
NFKB inhibitor alpha
chr19_+_14031746 0.30 ENST00000263379.4
interleukin 27 receptor subunit alpha
chr3_+_9731725 0.30 ENST00000433861.6
ENST00000383829.7
ENST00000684333.1
ENST00000683743.1
ENST00000683639.1
ENST00000684206.1
ENST00000420291.3
ENST00000424362.7
bromodomain and PHD finger containing 1
chr1_+_156642108 0.30 ENST00000457777.6
ENST00000329117.10
ENST00000424639.5
brevican
chr7_+_74028066 0.29 ENST00000431562.5
ENST00000320492.11
ENST00000438906.5
elastin
chr1_+_156642148 0.29 ENST00000361588.5
brevican
chr1_+_37793865 0.29 ENST00000397631.7
mannosidase endo-alpha like
chr2_-_74553934 0.29 ENST00000264094.8
ENST00000393937.6
ENST00000409986.5
lysyl oxidase like 3
chr1_+_236523873 0.29 ENST00000238181.11
galectin 8
chr7_+_74028127 0.29 ENST00000438880.5
ENST00000414324.5
ENST00000380562.8
ENST00000380575.8
ENST00000380584.8
ENST00000458204.5
ENST00000357036.9
ENST00000417091.5
ENST00000429192.5
ENST00000252034.12
ENST00000442310.5
ENST00000380553.8
ENST00000380576.9
ENST00000428787.5
ENST00000320399.10
elastin
chr14_-_106235582 0.29 ENST00000390607.2
immunoglobulin heavy variable 3-21
chr10_-_98011320 0.29 ENST00000309155.3
cartilage acidic protein 1
chr11_+_65525413 0.29 ENST00000527009.5
SCY1 like pseudokinase 1
chr19_+_10416773 0.28 ENST00000592685.5
phosphodiesterase 4A
chr7_+_74027770 0.28 ENST00000445912.5
ENST00000621115.4
elastin
chr2_+_32628026 0.28 ENST00000448773.5
ENST00000317907.9
tetratricopeptide repeat domain 27
chr16_-_1793694 0.28 ENST00000569769.1
ENST00000215539.4
splA/ryanodine receptor domain and SOCS box containing 3
insulin like growth factor binding protein acid labile subunit
chr18_+_58044343 0.28 ENST00000356462.10
ENST00000589054.5
ENST00000617539.1
ENST00000676024.1
ENST00000382850.8
ENST00000256830.13
NEDD4 like E3 ubiquitin protein ligase
chr5_-_16508951 0.28 ENST00000682628.1
reticulophagy regulator 1
chr15_+_76059973 0.28 ENST00000388942.8
transmembrane protein 266
chr3_-_194351290 0.28 ENST00000429275.1
ENST00000323830.4
carboxypeptidase N subunit 2
chr11_+_66291887 0.28 ENST00000327259.5
transmembrane protein 151A
chr14_+_102777555 0.28 ENST00000539721.5
ENST00000560463.5
TNF receptor associated factor 3
chr5_-_16508812 0.28 ENST00000683414.1
reticulophagy regulator 1
chr7_-_50561048 0.27 ENST00000380984.4
ENST00000357936.9
ENST00000426377.5
ENST00000615193.4
ENST00000617822.4
ENST00000622873.4
dopa decarboxylase
chr5_+_31639104 0.27 ENST00000438447.2
PDZ domain containing 2
chr8_-_100309904 0.27 ENST00000523481.5
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr11_+_64285472 0.27 ENST00000535675.5
ENST00000543383.5
G protein-coupled receptor 137
chr12_-_54973683 0.27 ENST00000532804.5
ENST00000531122.5
ENST00000533446.5
thymocyte expressed, positive selection associated 1
chr11_+_64285219 0.27 ENST00000377702.8
G protein-coupled receptor 137
chr7_+_30911845 0.26 ENST00000652696.1
ENST00000311813.11
aquaporin 1 (Colton blood group)
chr7_-_99500240 0.26 ENST00000426306.2
ENST00000337673.7
zinc finger protein 394
chr8_-_100309926 0.26 ENST00000341084.7
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr4_+_52051285 0.26 ENST00000295213.9
ENST00000419395.6
spermatogenesis associated 18
chr17_+_7014745 0.26 ENST00000546760.5
ENST00000552402.5
chromosome 17 open reading frame 49
chrX_+_9560465 0.26 ENST00000647060.1
transducin beta like 1 X-linked
chr15_-_89679360 0.26 ENST00000300055.10
perilipin 1
chr9_-_124941054 0.26 ENST00000373555.9
golgin A1
chr2_+_232697299 0.26 ENST00000476995.5
ENST00000427233.5
ENST00000629305.2
ENST00000428883.5
ENST00000456491.5
ENST00000409480.5
ENST00000492910.5
ENST00000464402.5
ENST00000490612.5
ENST00000475359.6
ENST00000421433.5
ENST00000425040.5
ENST00000430720.5
ENST00000409547.5
ENST00000373563.9
ENST00000423659.5
ENST00000409196.7
ENST00000488734.5
ENST00000409451.7
ENST00000429187.5
ENST00000440945.5
GRB10 interacting GYF protein 2
chr7_+_150800403 0.26 ENST00000484928.5
transmembrane protein 176A
chr3_-_119559529 0.26 ENST00000478182.5
CD80 molecule
chr1_-_33182030 0.26 ENST00000291416.10
tripartite motif containing 62
chr15_-_89679411 0.25 ENST00000430628.2
perilipin 1
chr1_+_113979460 0.25 ENST00000320334.5
olfactomedin like 3
chr10_+_120457197 0.25 ENST00000398250.6
phospholipid phosphatase 4
chr14_+_102777433 0.25 ENST00000392745.8
TNF receptor associated factor 3
chr20_+_297553 0.25 ENST00000500893.4
zinc finger CCHC-type containing 3
chr4_+_678189 0.25 ENST00000507804.1
myosin light chain 5
chr15_+_85380672 0.25 ENST00000361243.6
ENST00000560256.1
A-kinase anchoring protein 13
chr3_-_171809770 0.25 ENST00000331659.2
phospholipase D1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
1.2 3.5 GO:0035691 macrophage migration inhibitory factor signaling pathway(GO:0035691)
0.4 2.6 GO:0000255 allantoin metabolic process(GO:0000255)
0.4 2.5 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.3 1.0 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.3 0.9 GO:0034148 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
0.3 3.1 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.3 2.4 GO:0061709 reticulophagy(GO:0061709)
0.2 1.2 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.2 3.3 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.2 0.7 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 0.7 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.2 1.7 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.2 0.6 GO:0043335 protein unfolding(GO:0043335)
0.1 0.4 GO:0034125 negative regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034125) regulation of interleukin-4-mediated signaling pathway(GO:1902214)
0.1 0.4 GO:0051941 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.1 0.4 GO:0021793 chemorepulsion of branchiomotor axon(GO:0021793)
0.1 0.4 GO:1904897 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.1 0.4 GO:0030573 bile acid catabolic process(GO:0030573)
0.1 0.4 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.1 2.4 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.1 1.0 GO:0032100 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.1 0.6 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.1 1.0 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.1 1.0 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.1 0.3 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.5 GO:0050915 sensory perception of sour taste(GO:0050915)
0.1 0.3 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 0.3 GO:0071288 cellular response to mercury ion(GO:0071288)
0.1 0.4 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 2.5 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.1 0.3 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 0.3 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.1 0.8 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.3 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
0.1 0.3 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1 0.3 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
0.1 0.2 GO:0061565 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.1 0.1 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.1 0.5 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.1 0.5 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.1 1.1 GO:0042940 D-amino acid transport(GO:0042940)
0.1 0.2 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.1 0.4 GO:0050859 abortive mitotic cell cycle(GO:0033277) negative regulation of B cell receptor signaling pathway(GO:0050859)
0.1 0.5 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 1.1 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.1 0.3 GO:0002827 positive regulation of T-helper 1 type immune response(GO:0002827)
0.1 0.2 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.1 0.8 GO:0071316 cellular response to nicotine(GO:0071316)
0.1 0.6 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.1 1.2 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 1.0 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.4 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0 0.1 GO:0051695 actin filament uncapping(GO:0051695)
0.0 0.3 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.2 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0 0.7 GO:0006670 sphingosine metabolic process(GO:0006670)
0.0 1.8 GO:0010842 retina layer formation(GO:0010842)
0.0 0.8 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.2 GO:0042494 detection of bacterial lipoprotein(GO:0042494)
0.0 0.1 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.0 0.2 GO:0070383 DNA cytosine deamination(GO:0070383)
0.0 0.6 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.2 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.6 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.0 0.4 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.1 GO:0021678 third ventricle development(GO:0021678)
0.0 0.2 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0 0.2 GO:0036343 psychomotor behavior(GO:0036343)
0.0 0.4 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.2 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.1 GO:1902997 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.0 0.4 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 1.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.0 GO:0030221 basophil differentiation(GO:0030221)
0.0 0.1 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.0 0.5 GO:0051601 exocyst localization(GO:0051601)
0.0 0.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.2 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.3 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.2 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.1 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.0 0.2 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 3.6 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.6 GO:0015671 oxygen transport(GO:0015671)
0.0 0.3 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.3 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 1.1 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.6 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 0.6 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.1 GO:0035627 ceramide transport(GO:0035627)
0.0 0.2 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.1 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.0 0.3 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.2 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.1 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.2 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.6 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.2 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 0.1 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.2 GO:0051712 positive regulation of killing of cells of other organism(GO:0051712)
0.0 0.1 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.9 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
0.0 0.2 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.2 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.0 0.0 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.7 GO:0046710 GDP metabolic process(GO:0046710)
0.0 0.1 GO:0030222 eosinophil differentiation(GO:0030222)
0.0 0.0 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.1 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.2 GO:1902430 negative regulation of beta-amyloid formation(GO:1902430)
0.0 0.1 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.3 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 0.0 GO:0033590 response to cobalamin(GO:0033590)
0.0 0.1 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.3 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.2 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 0.1 GO:0051552 flavone metabolic process(GO:0051552)
0.0 0.1 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.4 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 1.1 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 1.0 GO:0007585 respiratory gaseous exchange(GO:0007585)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 11.5 GO:0042613 MHC class II protein complex(GO:0042613)
0.3 1.0 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.3 3.1 GO:0042611 MHC protein complex(GO:0042611)
0.1 0.4 GO:0097444 spine apparatus(GO:0097444)
0.1 1.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.3 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.1 0.9 GO:0071953 elastic fiber(GO:0071953)
0.1 0.9 GO:0036157 outer dynein arm(GO:0036157)
0.1 0.8 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 0.8 GO:0005879 axonemal microtubule(GO:0005879)
0.1 0.3 GO:0020003 symbiont-containing vacuole(GO:0020003)
0.1 0.4 GO:0002079 inner acrosomal membrane(GO:0002079) outer acrosomal membrane(GO:0002081)
0.1 0.3 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.4 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.2 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.2 GO:0035841 new growing cell tip(GO:0035841)
0.0 3.1 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.8 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.4 GO:0032010 phagolysosome(GO:0032010)
0.0 0.3 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.8 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.2 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
0.0 0.4 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.5 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.7 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485) integrin alpha8-beta1 complex(GO:0034678)
0.0 0.4 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 1.1 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.2 GO:0060091 kinocilium(GO:0060091)
0.0 0.3 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.2 GO:0001939 female pronucleus(GO:0001939) male pronucleus(GO:0001940)
0.0 0.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.5 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.1 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560)
0.0 0.7 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.3 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.1 GO:0097208 alveolar lamellar body(GO:0097208)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.6 6.9 GO:0032395 MHC class II receptor activity(GO:0032395)
0.5 3.5 GO:0042289 MHC class II protein binding(GO:0042289)
0.3 1.0 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.3 0.8 GO:0031862 prostanoid receptor binding(GO:0031862)
0.2 1.3 GO:0046979 TAP2 binding(GO:0046979)
0.1 0.3 GO:0005055 laminin receptor activity(GO:0005055)
0.1 0.3 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.1 0.5 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 1.5 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.4 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 0.4 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.1 0.5 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 0.6 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.1 1.8 GO:0042605 peptide antigen binding(GO:0042605)
0.1 1.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.9 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 1.1 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 1.2 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 2.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 0.5 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.4 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.2 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.0 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 1.1 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.9 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.3 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.3 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.4 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.3 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.1 GO:0008988 rRNA (adenine-N6-)-methyltransferase activity(GO:0008988)
0.0 0.1 GO:0009032 thymidine phosphorylase activity(GO:0009032) pyrimidine-nucleoside phosphorylase activity(GO:0016154)
0.0 0.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.6 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.3 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.1 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
0.0 0.6 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.2 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.9 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.6 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.6 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.2 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 1.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.4 GO:1990239 steroid hormone binding(GO:1990239)
0.0 0.6 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0035514 DNA demethylase activity(GO:0035514)
0.0 0.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.8 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 2.7 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.2 GO:0098988 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 0.1 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.0 0.5 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.3 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 0.1 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.6 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.5 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 1.1 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.1 GO:0097001 ceramide binding(GO:0097001)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.3 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.5 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.6 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.4 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.3 GO:0019871 potassium channel inhibitor activity(GO:0019870) sodium channel inhibitor activity(GO:0019871)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.4 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.3 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.2 GO:0017081 chloride channel regulator activity(GO:0017081)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 PID IL5 PATHWAY IL5-mediated signaling events
0.1 4.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 0.7 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 2.5 PID RAS PATHWAY Regulation of Ras family activation
0.0 2.3 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.5 PID IL27 PATHWAY IL27-mediated signaling events
0.0 2.0 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.9 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.4 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.4 PID EPO PATHWAY EPO signaling pathway
0.0 0.5 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.4 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.3 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.2 3.4 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 2.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 2.0 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.4 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.6 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 2.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.7 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 1.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 1.0 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 1.0 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 3.9 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.6 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.3 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.5 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 1.1 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.7 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.9 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.2 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.7 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter