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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for HLF_TEF

Z-value: 0.78

Motif logo

Transcription factors associated with HLF_TEF

Gene Symbol Gene ID Gene Info
ENSG00000108924.14 HLF
ENSG00000167074.15 TEF

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TEFhg38_v1_chr22_+_41367269_41367333,
hg38_v1_chr22_+_41381923_41381968
0.242.0e-01Click!
HLFhg38_v1_chr17_+_55266216_55266227-0.183.4e-01Click!

Activity profile of HLF_TEF motif

Sorted Z-values of HLF_TEF motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HLF_TEF

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_+_7784411 3.93 ENST00000613533.4
ENST00000614998.4
period circadian regulator 3
chr20_+_35172046 3.12 ENST00000216968.5
protein C receptor
chr2_-_112836702 2.82 ENST00000416750.1
ENST00000263341.7
ENST00000418817.5
interleukin 1 beta
chr17_-_43545707 2.25 ENST00000545089.5
ETS variant transcription factor 4
chr3_-_48088800 1.87 ENST00000423088.5
microtubule associated protein 4
chr2_-_31414694 1.85 ENST00000379416.4
xanthine dehydrogenase
chr17_-_43545891 1.85 ENST00000591713.5
ENST00000538265.5
ETS variant transcription factor 4
chr17_-_43546323 1.79 ENST00000545954.5
ENST00000319349.10
ETS variant transcription factor 4
chr3_-_48089203 1.70 ENST00000468075.2
ENST00000360240.10
microtubule associated protein 4
chr17_-_43545636 1.61 ENST00000393664.6
ETS variant transcription factor 4
chr1_+_7784251 1.60 ENST00000377532.8
ENST00000377541.5
period circadian regulator 3
chr19_-_35501878 1.45 ENST00000593342.5
ENST00000601650.1
ENST00000408915.6
dermokine
chr2_+_9961165 1.37 ENST00000405379.6
grainyhead like transcription factor 1
chr4_-_76007501 1.27 ENST00000264888.6
C-X-C motif chemokine ligand 9
chr8_-_6877928 1.25 ENST00000297439.4
defensin beta 1
chr5_+_151025343 1.22 ENST00000521632.1
glutathione peroxidase 3
chr20_-_57710539 1.19 ENST00000395816.7
ENST00000347215.8
prostate transmembrane protein, androgen induced 1
chr3_-_48088824 1.15 ENST00000439356.2
ENST00000395734.7
ENST00000426837.6
microtubule associated protein 4
chr17_+_41819201 1.15 ENST00000455106.1
FKBP prolyl isomerase 10
chr16_-_84618067 1.13 ENST00000262428.5
coactosin like F-actin binding protein 1
chr16_-_84618041 1.12 ENST00000564057.1
coactosin like F-actin binding protein 1
chr2_+_113127588 1.12 ENST00000409930.4
interleukin 1 receptor antagonist
chr11_+_35180279 1.09 ENST00000531873.5
CD44 molecule (Indian blood group)
chr10_+_75431605 1.08 ENST00000611255.5
leucine rich melanocyte differentiation associated
chr4_+_74365136 1.03 ENST00000244869.3
epiregulin
chr16_+_70646536 1.02 ENST00000288098.6
interleukin 34
chr21_-_43659460 0.97 ENST00000443485.1
ENST00000291560.7
heat shock transcription factor 2 binding protein
chr1_-_243850070 0.95 ENST00000366539.6
ENST00000672578.1
AKT serine/threonine kinase 3
chr5_-_140633167 0.94 ENST00000302014.11
CD14 molecule
chr5_-_140633690 0.90 ENST00000512545.1
ENST00000401743.6
CD14 molecule
chr11_+_69294107 0.90 ENST00000441339.3
ENST00000308946.3
ENST00000535407.1
myeloma overexpressed
chr15_+_81000913 0.88 ENST00000267984.4
talin rod domain containing 1
chr1_+_154405326 0.88 ENST00000368485.8
interleukin 6 receptor
chr11_+_35180342 0.87 ENST00000639002.1
CD44 molecule (Indian blood group)
chr9_+_98943705 0.79 ENST00000610452.1
collagen type XV alpha 1 chain
chr1_+_44746401 0.79 ENST00000372217.5
kinesin family member 2C
chr15_+_67125707 0.77 ENST00000540846.6
SMAD family member 3
chr4_+_118034480 0.75 ENST00000296499.6
N-deacetylase and N-sulfotransferase 3
chr1_+_154405193 0.75 ENST00000622330.4
ENST00000344086.8
interleukin 6 receptor
chr10_-_14330879 0.72 ENST00000357447.7
FERM domain containing 4A
chr9_+_98943898 0.70 ENST00000375001.8
collagen type XV alpha 1 chain
chr11_-_33774347 0.69 ENST00000526785.5
ENST00000534136.5
ENST00000530401.5
ENST00000265651.8
ENST00000448981.6
F-box protein 3
chr3_+_155080307 0.67 ENST00000360490.7
membrane metalloendopeptidase
chr10_-_17617235 0.65 ENST00000466335.1
3-hydroxyacyl-CoA dehydratase 1
chr7_+_23106267 0.64 ENST00000409689.5
ENST00000410047.1
kelch like family member 7
chr12_+_57229694 0.62 ENST00000557487.5
ENST00000328923.8
ENST00000555634.5
ENST00000556689.5
serine hydroxymethyltransferase 2
chr11_-_64879675 0.59 ENST00000359393.6
ENST00000433803.1
ENST00000411683.1
EH domain containing 1
chr11_-_64879709 0.59 ENST00000621096.4
EH domain containing 1
chr21_-_6467509 0.58 ENST00000624406.3
ENST00000398168.5
ENST00000624934.3
cystathionine beta-synthase like
chr18_+_35041387 0.57 ENST00000538170.6
ENST00000300249.10
ENST00000588910.5
microtubule associated protein RP/EB family member 2
chr2_-_213150236 0.56 ENST00000442445.1
ENST00000342002.6
IKAROS family zinc finger 2
chr17_-_41118369 0.55 ENST00000391413.4
keratin associated protein 4-11
chr6_+_54083423 0.54 ENST00000460844.6
ENST00000370876.6
muscular LMNA interacting protein
chr16_-_55833085 0.53 ENST00000360526.8
carboxylesterase 1
chr10_-_17617326 0.53 ENST00000326961.6
ENST00000361271.8
3-hydroxyacyl-CoA dehydratase 1
chr8_+_123182635 0.52 ENST00000276699.10
ENST00000522648.5
family with sequence similarity 83 member A
chr14_+_96256194 0.52 ENST00000216629.11
ENST00000553356.1
bradykinin receptor B1
chr5_+_96662046 0.52 ENST00000338252.7
ENST00000508830.5
calpastatin
chr12_-_52680398 0.52 ENST00000252244.3
keratin 1
chr8_-_101206064 0.50 ENST00000518336.5
ENST00000520454.1
zinc finger protein 706
chr11_-_62545629 0.49 ENST00000528508.5
ENST00000533365.5
AHNAK nucleoprotein
chr3_-_197183849 0.49 ENST00000443183.5
discs large MAGUK scaffold protein 1
chr1_+_65147657 0.48 ENST00000546702.5
adenylate kinase 4
chr21_+_43719095 0.46 ENST00000468090.5
ENST00000291565.9
pyridoxal kinase
chr1_+_115029823 0.45 ENST00000256592.3
thyroid stimulating hormone subunit beta
chr12_+_57230086 0.43 ENST00000414700.7
ENST00000557703.5
serine hydroxymethyltransferase 2
chr5_-_147782681 0.42 ENST00000616793.5
ENST00000333010.6
ENST00000265272.9
janus kinase and microtubule interacting protein 2
chr12_+_57230301 0.42 ENST00000553474.5
serine hydroxymethyltransferase 2
chr20_+_4686448 0.41 ENST00000379440.9
ENST00000424424.2
ENST00000457586.2
prion protein
chr3_-_99876193 0.40 ENST00000383694.3
filamin A interacting protein 1 like
chr3_-_197183806 0.39 ENST00000671246.1
ENST00000660553.1
discs large MAGUK scaffold protein 1
chr8_+_69492793 0.39 ENST00000616868.1
ENST00000419716.7
ENST00000402687.9
sulfatase 1
chr12_-_70637405 0.39 ENST00000548122.2
ENST00000551525.5
ENST00000550358.5
ENST00000334414.11
protein tyrosine phosphatase receptor type B
chr1_+_65147830 0.38 ENST00000395334.6
adenylate kinase 4
chr3_+_183265302 0.38 ENST00000465010.1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr12_-_75209701 0.38 ENST00000350228.6
ENST00000298972.5
potassium voltage-gated channel subfamily C member 2
chr20_+_38581186 0.37 ENST00000373348.4
ENST00000537425.2
ENST00000416116.2
adipogenin
chr20_+_63739751 0.37 ENST00000266077.5
SLC2A4 regulator
chr12_+_57230336 0.37 ENST00000555773.5
ENST00000554975.5
ENST00000449049.7
serine hydroxymethyltransferase 2
chr19_-_3985451 0.37 ENST00000309311.7
eukaryotic translation elongation factor 2
chr12_-_75209814 0.36 ENST00000549446.6
potassium voltage-gated channel subfamily C member 2
chr19_-_2042066 0.36 ENST00000591588.1
ENST00000591142.5
MAPK interacting serine/threonine kinase 2
chr11_-_106077401 0.35 ENST00000526793.5
kelch repeat and BTB domain containing 3
chr13_-_33205997 0.35 ENST00000399365.7
StAR related lipid transfer domain containing 13
chr17_-_41382298 0.35 ENST00000394001.3
keratin 34
chr12_+_93569814 0.34 ENST00000340600.6
suppressor of cytokine signaling 2
chr1_-_226309198 0.33 ENST00000481685.1
lin-9 DREAM MuvB core complex component
chr16_-_30091226 0.33 ENST00000279386.6
ENST00000627355.2
T-box transcription factor 6
chr5_+_96662314 0.32 ENST00000674702.1
calpastatin
chr15_+_58138368 0.32 ENST00000219919.9
ENST00000536493.1
aquaporin 9
chr16_-_55833186 0.32 ENST00000361503.8
ENST00000422046.6
carboxylesterase 1
chr1_+_65147514 0.32 ENST00000545314.5
adenylate kinase 4
chr10_+_92291155 0.31 ENST00000358935.3
membrane associated ring-CH-type finger 5
chr5_-_179623098 0.30 ENST00000630639.1
ENST00000329433.10
ENST00000510411.5
heterogeneous nuclear ribonucleoprotein H1
chr17_-_75855204 0.30 ENST00000589642.5
ENST00000593002.1
ENST00000590221.5
ENST00000587374.5
ENST00000585462.5
ENST00000254806.8
ENST00000433525.6
ENST00000626827.2
WW domain binding protein 2
chr1_-_150579530 0.30 ENST00000307940.3
ENST00000678610.1
ENST00000678770.1
ENST00000369026.3
MCL1 apoptosis regulator, BCL2 family member
chr3_-_99876104 0.29 ENST00000471562.1
ENST00000495625.2
filamin A interacting protein 1 like
chr20_+_16748358 0.29 ENST00000246081.3
otoraplin
chr17_-_78128630 0.29 ENST00000306591.11
transmembrane channel like 6
chr7_+_44606563 0.28 ENST00000439616.6
oxoglutarate dehydrogenase
chr5_+_96662214 0.27 ENST00000395812.6
calpastatin
chr5_+_96662366 0.26 ENST00000675179.1
ENST00000421689.6
ENST00000674984.1
ENST00000512620.5
calpastatin
chr6_-_30075767 0.26 ENST00000244360.8
ENST00000376751.8
ring finger protein 39
chrX_+_41447322 0.26 ENST00000378220.2
ENST00000342595.2
nyctalopin
chr3_-_99850976 0.26 ENST00000487087.5
filamin A interacting protein 1 like
chrX_-_33211540 0.26 ENST00000357033.9
dystrophin
chr2_-_166149204 0.25 ENST00000635750.1
sodium voltage-gated channel alpha subunit 1
chr2_-_166149120 0.25 ENST00000641575.1
ENST00000641603.1
sodium voltage-gated channel alpha subunit 1
chr11_-_106077313 0.24 ENST00000531837.2
ENST00000534815.1
kelch repeat and BTB domain containing 3
chr9_+_32552305 0.24 ENST00000451672.2
ENST00000644531.1
small integral membrane protein 27
chr1_+_113905156 0.24 ENST00000650596.1
DNA cross-link repair 1B
chr2_+_190343561 0.24 ENST00000322522.8
ENST00000392329.7
ENST00000430311.5
inositol polyphosphate-1-phosphatase
chr9_+_107283256 0.24 ENST00000358015.8
RAD23 homolog B, nucleotide excision repair protein
chr7_+_44606578 0.23 ENST00000443864.6
ENST00000447398.5
ENST00000449767.5
ENST00000419661.5
oxoglutarate dehydrogenase
chr4_-_21948733 0.23 ENST00000447367.6
ENST00000382152.7
potassium voltage-gated channel interacting protein 4
chr1_+_65264694 0.23 ENST00000263441.11
ENST00000395325.7
DnaJ heat shock protein family (Hsp40) member C6
chr8_+_67952028 0.21 ENST00000288368.5
phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2
chr17_-_78128778 0.20 ENST00000589553.5
transmembrane channel like 6
chr13_-_46052712 0.20 ENST00000242848.8
ENST00000679008.1
ENST00000282007.7
zinc finger CCCH-type containing 13
chr19_-_4065732 0.20 ENST00000601588.1
zinc finger and BTB domain containing 7A
chr7_+_20647388 0.20 ENST00000258738.10
ATP binding cassette subfamily B member 5
chr1_-_161238163 0.20 ENST00000367982.8
nuclear receptor subfamily 1 group I member 3
chr12_-_113136224 0.20 ENST00000546530.5
ENST00000261729.9
RAS protein activator like 1
chr6_-_132714045 0.20 ENST00000367928.5
vanin 1
chr20_+_4686320 0.19 ENST00000430350.2
prion protein
chr3_+_124584625 0.19 ENST00000291478.9
ENST00000682363.1
ENST00000454902.1
kalirin RhoGEF kinase
chr2_-_166128004 0.19 ENST00000303395.9
ENST00000674923.1
ENST00000637988.1
ENST00000635776.1
sodium voltage-gated channel alpha subunit 1
chr1_-_150579738 0.19 ENST00000620947.4
MCL1 apoptosis regulator, BCL2 family member
chr17_-_81937320 0.19 ENST00000577624.5
ENST00000403172.8
ENST00000619204.4
ENST00000629768.2
pyrroline-5-carboxylate reductase 1
chr11_+_62728465 0.19 ENST00000316461.9
tetratricopeptide repeat domain 9C
chr6_+_72216442 0.18 ENST00000425662.6
ENST00000453976.6
regulating synaptic membrane exocytosis 1
chr2_+_68467544 0.18 ENST00000303795.9
aprataxin and PNKP like factor
chr22_+_26621952 0.18 ENST00000354760.4
crystallin beta A4
chr9_+_27524285 0.18 ENST00000276943.3
interferon kappa
chr17_-_81937277 0.18 ENST00000405481.8
ENST00000329875.13
ENST00000585215.5
pyrroline-5-carboxylate reductase 1
chr1_-_108192818 0.18 ENST00000370041.4
solute carrier family 25 member 24
chr6_+_96924720 0.18 ENST00000369261.9
kelch like family member 32
chr1_-_161238196 0.17 ENST00000367983.9
ENST00000506209.5
ENST00000367980.6
ENST00000628566.2
nuclear receptor subfamily 1 group I member 3
chr13_+_23180960 0.17 ENST00000218867.4
sarcoglycan gamma
chr17_-_81937221 0.17 ENST00000402252.6
ENST00000583564.5
ENST00000585244.1
ENST00000337943.9
ENST00000579698.5
pyrroline-5-carboxylate reductase 1
chr3_+_141384790 0.17 ENST00000507722.5
zinc finger and BTB domain containing 38
chr1_+_196888014 0.17 ENST00000367416.6
ENST00000608469.6
ENST00000251424.8
ENST00000367418.2
complement factor H related 4
chr1_-_178871060 0.16 ENST00000234816.7
angiopoietin like 1
chr9_-_91423819 0.16 ENST00000297689.4
nuclear factor, interleukin 3 regulated
chr1_-_161238085 0.16 ENST00000512372.5
ENST00000437437.6
ENST00000412844.6
ENST00000428574.6
ENST00000442691.6
ENST00000505005.5
ENST00000508740.5
ENST00000367981.7
ENST00000502985.5
ENST00000504010.5
ENST00000508387.5
ENST00000511676.5
ENST00000511748.5
ENST00000511944.5
ENST00000515621.5
ENST00000367984.8
ENST00000367985.7
nuclear receptor subfamily 1 group I member 3
chr3_+_159069252 0.16 ENST00000640015.1
ENST00000476809.7
ENST00000485419.7
IQCJ-SCHIP1 readthrough
chr6_+_24126186 0.16 ENST00000378478.5
ENST00000378491.9
ENST00000378477.2
neurensin 1
chr10_+_18340821 0.15 ENST00000612743.1
ENST00000612134.4
calcium voltage-gated channel auxiliary subunit beta 2
chr7_-_92833896 0.15 ENST00000265734.8
cyclin dependent kinase 6
chr13_-_37598750 0.15 ENST00000379743.8
ENST00000379742.4
ENST00000379749.8
ENST00000379747.9
ENST00000541179.5
ENST00000541481.5
periostin
chr5_-_147906530 0.15 ENST00000318315.5
ENST00000515291.1
chromosome 5 open reading frame 46
chr9_+_69205141 0.15 ENST00000649134.1
ENST00000539225.2
ENST00000650084.1
ENST00000648402.1
tight junction protein 2
chr11_-_72434330 0.15 ENST00000542555.2
ENST00000535990.5
ENST00000294053.9
ENST00000538039.6
ENST00000340729.9
caseinolytic mitochondrial matrix peptidase chaperone subunit B
chr7_+_20647343 0.14 ENST00000443026.6
ENST00000406935.5
ATP binding cassette subfamily B member 5
chr19_-_41439528 0.14 ENST00000301183.15
ENST00000417807.7
ENST00000590641.6
distal membrane arm assembly complex 2
chr20_-_50931364 0.14 ENST00000645081.1
ENST00000396029.8
ENST00000396032.8
ENST00000621696.5
ENST00000673732.1
activity dependent neuroprotector homeobox
chr3_+_98166696 0.14 ENST00000641450.1
olfactory receptor family 5 subfamily H member 15
chr11_-_35360050 0.14 ENST00000644868.1
ENST00000643454.1
ENST00000646080.1
solute carrier family 1 member 2
chr20_+_2101807 0.14 ENST00000381482.8
serine/threonine kinase 35
chr1_+_11189347 0.14 ENST00000376819.4
angiopoietin like 7
chr19_-_54189670 0.13 ENST00000391754.5
membrane bound O-acyltransferase domain containing 7
chr11_-_14972273 0.13 ENST00000396372.2
ENST00000361010.7
ENST00000331587.9
calcitonin related polypeptide alpha
chr22_-_29061831 0.13 ENST00000216071.5
chromosome 22 open reading frame 31
chr4_+_186266183 0.13 ENST00000403665.7
ENST00000492972.6
ENST00000264692.8
coagulation factor XI
chr7_+_44606619 0.12 ENST00000222673.6
ENST00000444676.5
ENST00000631326.2
oxoglutarate dehydrogenase
chr1_+_161118083 0.12 ENST00000368009.7
ENST00000368007.8
ENST00000392190.9
ENST00000368008.5
nitrilase 1
chr10_+_18340699 0.12 ENST00000377329.10
calcium voltage-gated channel auxiliary subunit beta 2
chr5_+_127653048 0.12 ENST00000395322.3
cortexin 3
chr18_+_13824149 0.11 ENST00000589410.2
melanocortin 5 receptor
chr3_-_58214671 0.11 ENST00000460422.1
ENST00000483681.5
deoxyribonuclease 1 like 3
chr19_+_33374312 0.11 ENST00000585933.2
CCAAT enhancer binding protein gamma
chr3_+_119782094 0.10 ENST00000393716.8
nuclear receptor subfamily 1 group I member 2
chr8_+_24440930 0.10 ENST00000441335.6
ENST00000175238.10
ENST00000380789.5
ADAM metallopeptidase domain 7
chr14_+_20110739 0.10 ENST00000641386.2
ENST00000641633.2
olfactory receptor family 4 subfamily K member 17
chr4_-_64409444 0.10 ENST00000381210.8
ENST00000507440.5
trans-2,3-enoyl-CoA reductase like
chr1_-_226309071 0.10 ENST00000359525.2
ENST00000681046.1
ENST00000460719.5
lin-9 DREAM MuvB core complex component
chrX_+_153056408 0.10 ENST00000619635.1
PNMA family member 3
chrX_+_153056458 0.10 ENST00000593810.3
PNMA family member 3
chr7_+_90403386 0.10 ENST00000287916.8
ENST00000394604.5
ENST00000496677.6
ENST00000394605.2
ENST00000480135.1
claudin 12
novel transcript
chr3_+_157436842 0.10 ENST00000295927.4
pentraxin 3
chr9_+_133534697 0.09 ENST00000651351.2
ADAMTS like 2
chr1_+_56854764 0.09 ENST00000361249.4
complement C8 alpha chain
chr4_-_95549199 0.09 ENST00000504962.1
ENST00000506749.5
unc-5 netrin receptor C
chr14_+_101809855 0.09 ENST00000557714.1
ENST00000445439.7
ENST00000334743.9
ENST00000557095.5
protein phosphatase 2 regulatory subunit B'gamma
chr19_+_1450113 0.09 ENST00000590469.6
ENST00000590877.5
ENST00000233607.6
APC regulator of WNT signaling pathway 2
chr17_-_28614174 0.09 ENST00000530121.5
ENST00000301037.11
ENST00000531839.5
ribosomal protein S6 kinase related
novel protein
chr12_+_103930600 0.09 ENST00000680316.1
ENST00000679861.1
heat shock protein 90 beta family member 1
chr1_-_101025763 0.09 ENST00000342173.11
ENST00000488176.1
ENST00000370109.8
diphthamide biosynthesis 5
chr2_-_87825952 0.08 ENST00000398146.4
RANBP2 like and GRIP domain containing 2
chr5_-_43557689 0.07 ENST00000338972.8
ENST00000511321.5
ENST00000515338.1
poly(A) binding protein interacting protein 1
chr17_-_44067585 0.07 ENST00000591247.6
LSM12 homolog
chr9_-_125484490 0.07 ENST00000444226.1
MAPK associated protein 1
chr6_+_96924614 0.06 ENST00000536676.5
ENST00000539200.5
ENST00000544166.5
kelch like family member 32
chr17_-_34363224 0.06 ENST00000225842.4
C-C motif chemokine ligand 1
chr21_+_25639251 0.06 ENST00000480456.6
junctional adhesion molecule 2
chr18_-_5396265 0.06 ENST00000579951.2
erythrocyte membrane protein band 4.1 like 3
chr6_-_116126120 0.06 ENST00000452729.1
ENST00000651968.1
ENST00000243222.8
collagen type X alpha 1 chain
chr11_-_124313949 0.06 ENST00000641015.1
olfactory receptor family 8 subfamily D member 1
chr16_+_72054477 0.06 ENST00000355906.10
ENST00000570083.5
ENST00000228226.12
ENST00000398131.6
ENST00000569639.5
ENST00000564499.5
ENST00000357763.8
ENST00000613898.1
ENST00000562526.5
ENST00000565574.5
ENST00000568417.6
haptoglobin
chr7_-_80512041 0.06 ENST00000398291.4
G protein subunit alpha transducin 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0060559 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.8 4.7 GO:0051012 microtubule sliding(GO:0051012)
0.6 1.9 GO:0046110 xanthine metabolic process(GO:0046110)
0.4 1.6 GO:0002384 hepatic immune response(GO:0002384)
0.4 1.8 GO:0038123 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.4 1.4 GO:1903575 cornified envelope assembly(GO:1903575)
0.3 1.3 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.3 1.8 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.2 0.9 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.2 1.0 GO:0045410 positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.2 1.2 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.2 0.7 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.2 0.6 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.2 2.0 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.2 0.6 GO:1990535 neuron projection maintenance(GO:1990535)
0.1 5.5 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.1 1.0 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 1.2 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.1 0.4 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.8 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 1.3 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 1.4 GO:0002934 desmosome organization(GO:0002934)
0.1 0.3 GO:0048058 compound eye corneal lens development(GO:0048058)
0.1 0.6 GO:0006535 cysteine biosynthetic process from serine(GO:0006535)
0.1 0.8 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.4 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.1 1.2 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.1 0.8 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 0.3 GO:0015855 canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.1 0.5 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 0.5 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.1 0.7 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 1.1 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 1.0 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.1 1.3 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.1 1.4 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.1 0.4 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.9 GO:1903764 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 1.0 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.3 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.7 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 2.3 GO:0050832 defense response to fungus(GO:0050832)
0.0 3.5 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 0.1 GO:0001983 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.0 0.5 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.2 GO:0031627 telomeric loop formation(GO:0031627)
0.0 0.1 GO:1990523 bone regeneration(GO:1990523)
0.0 0.3 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.0 0.1 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
0.0 0.3 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.2 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.1 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.3 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.2 GO:0060125 habituation(GO:0046959) negative regulation of growth hormone secretion(GO:0060125)
0.0 0.2 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.7 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 1.1 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.0 0.2 GO:0000012 single strand break repair(GO:0000012) positive regulation of DNA ligation(GO:0051106)
0.0 0.1 GO:0010835 regulation of protein ADP-ribosylation(GO:0010835) nitric oxide homeostasis(GO:0033484)
0.0 1.1 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.4 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 1.5 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.0 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.2 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.1 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.0 0.5 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.1 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.3 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.1 GO:0046618 drug export(GO:0046618)
0.0 0.1 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.3 1.3 GO:1990742 microvesicle(GO:1990742)
0.2 1.8 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 1.2 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.2 1.8 GO:0070552 BRISC complex(GO:0070552)
0.2 2.0 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 1.5 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.1 0.8 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.6 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.2 GO:0071942 XPC complex(GO:0071942)
0.0 0.9 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 4.4 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 1.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.4 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.6 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.3 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.9 GO:0030673 axolemma(GO:0030673)
0.0 1.9 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 1.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 1.1 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.5 GO:0043034 costamere(GO:0043034)
0.0 2.3 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.4 1.3 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.4 1.2 GO:0080023 3R-hydroxyacyl-CoA dehydratase activity(GO:0080023)
0.4 1.1 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.3 1.9 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.3 1.8 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.3 1.8 GO:0004793 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.3 1.3 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.2 1.2 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.2 0.6 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.2 0.9 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.2 2.8 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 1.0 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 1.4 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 0.8 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.4 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1 0.8 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.1 0.6 GO:1903135 cupric ion binding(GO:1903135)
0.1 0.3 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.1 0.5 GO:0004882 androgen receptor activity(GO:0004882)
0.1 1.2 GO:0008430 selenium binding(GO:0008430)
0.1 0.8 GO:0019237 centromeric DNA binding(GO:0019237)
0.1 0.6 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.1 0.4 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.1 0.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.5 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.9 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.3 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.3 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 1.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.5 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 1.1 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.5 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.1 GO:0031716 calcitonin receptor binding(GO:0031716)
0.0 0.5 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.4 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.2 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.3 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 1.2 GO:0050699 WW domain binding(GO:0050699)
0.0 0.8 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.5 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.1 GO:0050436 microfibril binding(GO:0050436)
0.0 0.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.3 GO:0002162 dystroglycan binding(GO:0002162)
0.0 7.7 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 5.8 GO:0008017 microtubule binding(GO:0008017)
0.0 0.0 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 1.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.0 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 0.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 7.5 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.8 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.9 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.0 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 1.5 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.3 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.6 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.8 PID AURORA B PATHWAY Aurora B signaling
0.0 0.9 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.4 ST P38 MAPK PATHWAY p38 MAPK Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 1.9 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 1.6 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 2.0 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.0 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 3.2 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 2.0 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.3 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.9 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.8 REACTOME KINESINS Genes involved in Kinesins
0.0 1.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.8 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels