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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for HMGA1

Z-value: 0.92

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Transcription factors associated with HMGA1

Gene Symbol Gene ID Gene Info
HMGA1
ENSG00000137309.20 HMGA1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HMGA1hg38_v1_chr6_+_34236865_342368870.823.7e-08Click!

Activity profile of HMGA1 motif

Sorted Z-values of HMGA1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HMGA1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr1_-_153094521 3.25 ENST00000368750.8
SPRR2E
small proline rich protein 2E
chr9_-_41908681 3.12 ENST00000476961.5
CNTNAP3B
contactin associated protein family member 3B
chr16_-_46621345 3.09 ENST00000303383.8
SHCBP1
SHC binding and spindle associated 1
chr3_-_74521140 3.00 ENST00000263665.6
CNTN3
contactin 3
chr4_+_68447453 2.90 ENST00000305363.9
TMPRSS11E
transmembrane serine protease 11E
chr4_-_142305935 2.77 ENST00000511838.5
INPP4B
inositol polyphosphate-4-phosphatase type II B
chr18_+_31447732 2.63 ENST00000257189.5
DSG3
desmoglein 3
chr7_-_41703062 2.32 ENST00000242208.5
INHBA
inhibin subunit beta A
chr6_+_151325665 2.26 ENST00000354675.10
AKAP12
A-kinase anchoring protein 12
chr11_-_55936400 2.22 ENST00000301532.3
OR5I1
olfactory receptor family 5 subfamily I member 1
chr5_-_39270623 2.14 ENST00000512138.1
ENST00000646045.2
FYB1
FYN binding protein 1
chr10_+_84452208 2.12 ENST00000480006.1
CCSER2
coiled-coil serine rich protein 2
chr12_-_84892120 2.09 ENST00000680379.1
SLC6A15
solute carrier family 6 member 15
chr6_+_36029082 2.05 ENST00000472333.1
MAPK14
mitogen-activated protein kinase 14
chr7_+_134745460 2.03 ENST00000436461.6
CALD1
caldesmon 1
chr1_-_153070840 1.99 ENST00000368755.2
SPRR2B
small proline rich protein 2B
chr2_+_102311502 1.87 ENST00000404917.6
ENST00000410040.5
IL1RL1
IL18R1
interleukin 1 receptor like 1
interleukin 18 receptor 1
chr3_+_130931893 1.79 ENST00000504612.5
ATP2C1
ATPase secretory pathway Ca2+ transporting 1
chr2_+_209580024 1.78 ENST00000392194.5
MAP2
microtubule associated protein 2
chr5_+_69167117 1.76 ENST00000506572.5
ENST00000256442.10
CCNB1
cyclin B1
chr7_-_93890160 1.73 ENST00000451238.1
TFPI2
tissue factor pathway inhibitor 2
chr1_-_153041111 1.70 ENST00000360379.4
SPRR2D
small proline rich protein 2D
chr18_-_12656716 1.69 ENST00000462226.1
ENST00000497844.6
ENST00000309836.9
ENST00000453447.6
SPIRE1
spire type actin nucleation factor 1
chr21_-_26843012 1.61 ENST00000517777.6
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr21_-_26843063 1.57 ENST00000678221.1
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr9_-_39288138 1.53 ENST00000297668.10
CNTNAP3
contactin associated protein family member 3
chr12_+_40692413 1.49 ENST00000551295.7
ENST00000547702.5
ENST00000551424.5
CNTN1
contactin 1
chr4_+_168092530 1.49 ENST00000359299.8
ANXA10
annexin A10
chr1_+_152908538 1.49 ENST00000368764.4
IVL
involucrin
chr3_-_185821092 1.47 ENST00000421047.3
IGF2BP2
insulin like growth factor 2 mRNA binding protein 2
chr4_-_142305826 1.44 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase type II B
chr4_+_73436244 1.41 ENST00000226359.2
AFP
alpha fetoprotein
chr4_+_73436198 1.39 ENST00000395792.7
AFP
alpha fetoprotein
chr3_-_197260369 1.37 ENST00000658155.1
ENST00000453607.5
DLG1
discs large MAGUK scaffold protein 1
chr4_-_56681288 1.37 ENST00000556376.6
ENST00000420433.6
HOPX
HOP homeobox
chr10_-_104338431 1.33 ENST00000647721.1
ENST00000337478.3
ITPRIP
inositol 1,4,5-trisphosphate receptor interacting protein
chr2_+_190927649 1.30 ENST00000409428.5
ENST00000409215.5
GLS
glutaminase
chr3_-_197184131 1.30 ENST00000452595.5
DLG1
discs large MAGUK scaffold protein 1
chr10_+_116427839 1.30 ENST00000369230.4
PNLIPRP3
pancreatic lipase related protein 3
chr15_-_99249523 1.29 ENST00000560235.1
ENST00000394132.7
ENST00000560860.5
ENST00000558078.5
ENST00000560772.5
TTC23
tetratricopeptide repeat domain 23
chr16_-_18876305 1.28 ENST00000563235.5
SMG1
SMG1 nonsense mediated mRNA decay associated PI3K related kinase
chr17_-_59151794 1.28 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr12_-_50025394 1.27 ENST00000454520.6
ENST00000546595.5
ENST00000548824.5
ENST00000549777.5
ENST00000546723.5
ENST00000427314.6
ENST00000552157.5
ENST00000552310.5
ENST00000548644.5
ENST00000546786.5
ENST00000550149.5
ENST00000546764.5
ENST00000552004.2
ENST00000548320.5
ENST00000312377.10
ENST00000547905.5
ENST00000550651.5
ENST00000551145.5
ENST00000552921.5
RACGAP1
Rac GTPase activating protein 1
chr11_-_7796942 1.26 ENST00000329434.3
OR5P2
olfactory receptor family 5 subfamily P member 2
chr20_+_3786772 1.26 ENST00000344256.10
ENST00000379598.9
CDC25B
cell division cycle 25B
chr4_+_154563003 1.25 ENST00000302068.9
ENST00000509493.1
FGB
fibrinogen beta chain
chr5_-_147831627 1.24 ENST00000510027.2
SPINK1
serine peptidase inhibitor Kazal type 1
chr9_+_74615582 1.23 ENST00000396204.2
RORB
RAR related orphan receptor B
chr14_+_32329341 1.22 ENST00000557354.5
ENST00000557102.1
ENST00000557272.1
AKAP6
A-kinase anchoring protein 6
chr1_+_84164962 1.20 ENST00000614872.4
ENST00000394839.6
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr12_-_10826358 1.18 ENST00000240619.2
TAS2R10
taste 2 receptor member 10
chrX_+_80420466 1.17 ENST00000308293.5
TENT5D
terminal nucleotidyltransferase 5D
chr6_+_27138588 1.15 ENST00000615353.1
H4C9
H4 clustered histone 9
chr13_+_108596152 1.11 ENST00000356711.7
ENST00000251041.10
MYO16
myosin XVI
chr4_-_155866277 1.10 ENST00000537611.3
ASIC5
acid sensing ion channel subunit family member 5
chr2_+_101697699 1.10 ENST00000350878.8
ENST00000350198.8
ENST00000324219.8
ENST00000425019.5
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr3_+_99638475 1.05 ENST00000452013.5
ENST00000261037.7
ENST00000652472.1
ENST00000273342.8
ENST00000621757.1
COL8A1
collagen type VIII alpha 1 chain
chr3_+_172754457 1.05 ENST00000441497.6
ECT2
epithelial cell transforming 2
chr6_-_130956371 1.04 ENST00000639623.1
ENST00000525193.5
ENST00000527659.5
EPB41L2
erythrocyte membrane protein band 4.1 like 2
chr5_-_147831663 1.04 ENST00000296695.10
SPINK1
serine peptidase inhibitor Kazal type 1
chr4_-_22443110 1.03 ENST00000508133.5
ADGRA3
adhesion G protein-coupled receptor A3
chr13_+_31945826 1.03 ENST00000647500.1
FRY
FRY microtubule binding protein
chr12_+_21527017 1.02 ENST00000535033.5
SPX
spexin hormone
chr1_-_158554405 1.02 ENST00000641282.1
ENST00000641622.1
OR6Y1
olfactory receptor family 6 subfamily Y member 1
chr3_+_57890011 1.01 ENST00000494088.6
ENST00000438794.5
SLMAP
sarcolemma associated protein
chr7_-_122699108 1.01 ENST00000340112.3
RNF133
ring finger protein 133
chr14_-_34713759 1.01 ENST00000673315.1
CFL2
cofilin 2
chr10_+_74176537 1.00 ENST00000672394.1
ADK
adenosine kinase
chr3_-_122383218 0.99 ENST00000479899.5
ENST00000291458.9
ENST00000497726.5
MIX23
mitochondrial matrix import factor 23
chr3_-_197183963 0.99 ENST00000653795.1
DLG1
discs large MAGUK scaffold protein 1
chr12_-_119804472 0.97 ENST00000678087.1
ENST00000677993.1
CIT
citron rho-interacting serine/threonine kinase
chr12_-_8650529 0.97 ENST00000543467.5
MFAP5
microfibril associated protein 5
chr11_+_69641146 0.95 ENST00000227507.3
ENST00000536559.1
CCND1
cyclin D1
chr1_+_115029823 0.94 ENST00000256592.3
TSHB
thyroid stimulating hormone subunit beta
chr2_+_230759918 0.94 ENST00000614925.1
CAB39
calcium binding protein 39
chr12_-_91111460 0.94 ENST00000266718.5
LUM
lumican
chr22_-_28306645 0.93 ENST00000612946.4
TTC28
tetratricopeptide repeat domain 28
chr1_-_197067234 0.92 ENST00000367412.2
F13B
coagulation factor XIII B chain
chr17_-_445939 0.92 ENST00000329099.4
RFLNB
refilin B
chr3_-_149377637 0.92 ENST00000305366.8
TM4SF1
transmembrane 4 L six family member 1
chr1_-_28058087 0.91 ENST00000373864.5
EYA3
EYA transcriptional coactivator and phosphatase 3
chr1_+_192158448 0.91 ENST00000367460.4
RGS18
regulator of G protein signaling 18
chr8_-_121641424 0.91 ENST00000303924.5
HAS2
hyaluronan synthase 2
chr11_+_89924064 0.90 ENST00000623787.3
TRIM49D2
tripartite motif containing 49D2
chr7_+_130207847 0.90 ENST00000297819.4
SSMEM1
serine rich single-pass membrane protein 1
chr5_-_126595237 0.89 ENST00000637206.1
ENST00000553117.5
ALDH7A1
aldehyde dehydrogenase 7 family member A1
chr22_-_28711931 0.89 ENST00000434810.5
ENST00000456369.5
CHEK2
checkpoint kinase 2
chr6_-_25830557 0.89 ENST00000468082.1
SLC17A1
solute carrier family 17 member 1
chr18_+_63775395 0.87 ENST00000398019.7
SERPINB7
serpin family B member 7
chr19_-_48513161 0.87 ENST00000673139.1
LMTK3
lemur tyrosine kinase 3
chr3_-_197183849 0.87 ENST00000443183.5
DLG1
discs large MAGUK scaffold protein 1
chr17_-_41065879 0.86 ENST00000394015.3
KRTAP2-4
keratin associated protein 2-4
chr15_+_80441229 0.86 ENST00000533983.5
ENST00000527771.5
ENST00000525103.1
ARNT2
aryl hydrocarbon receptor nuclear translocator 2
chr9_+_72628020 0.85 ENST00000646619.1
TMC1
transmembrane channel like 1
chr11_+_55811367 0.84 ENST00000625203.2
OR5L1
olfactory receptor family 5 subfamily L member 1
chr3_-_151329539 0.84 ENST00000325602.6
P2RY13
purinergic receptor P2Y13
chr10_-_93482194 0.84 ENST00000358334.9
ENST00000371488.3
MYOF
myoferlin
chr4_+_141636563 0.82 ENST00000320650.9
ENST00000296545.11
IL15
interleukin 15
chr8_-_48921419 0.82 ENST00000020945.4
SNAI2
snail family transcriptional repressor 2
chr12_+_12891554 0.82 ENST00000014914.6
GPRC5A
G protein-coupled receptor class C group 5 member A
chr9_-_39239174 0.81 ENST00000358144.6
CNTNAP3
contactin associated protein family member 3
chr4_+_141636611 0.80 ENST00000514653.5
IL15
interleukin 15
chr2_-_162536955 0.80 ENST00000621889.1
KCNH7
potassium voltage-gated channel subfamily H member 7
chr1_+_84181630 0.80 ENST00000610457.1
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr12_-_16600703 0.80 ENST00000616247.4
LMO3
LIM domain only 3
chr7_+_77840122 0.80 ENST00000450574.5
ENST00000248550.7
PHTF2
putative homeodomain transcription factor 2
chr2_+_209653171 0.79 ENST00000447185.5
MAP2
microtubule associated protein 2
chr8_+_127737610 0.79 ENST00000652288.1
MYC
MYC proto-oncogene, bHLH transcription factor
chr4_-_73988179 0.79 ENST00000296028.4
PPBP
pro-platelet basic protein
chr8_-_65789084 0.79 ENST00000379419.8
PDE7A
phosphodiesterase 7A
chr4_+_141636923 0.79 ENST00000529613.5
IL15
interleukin 15
chr22_-_28712136 0.78 ENST00000464581.6
CHEK2
checkpoint kinase 2
chr4_-_76007501 0.77 ENST00000264888.6
CXCL9
C-X-C motif chemokine ligand 9
chr12_+_4809176 0.76 ENST00000280684.3
KCNA6
potassium voltage-gated channel subfamily A member 6
chr19_+_926001 0.75 ENST00000263620.8
ARID3A
AT-rich interaction domain 3A
chr17_-_40984297 0.75 ENST00000377755.9
KRT40
keratin 40
chr4_-_89835617 0.73 ENST00000611107.1
ENST00000345009.8
ENST00000505199.5
ENST00000502987.5
SNCA
synuclein alpha
chr4_-_39032343 0.72 ENST00000381938.4
TMEM156
transmembrane protein 156
chr7_-_92134737 0.71 ENST00000450723.5
CYP51A1
cytochrome P450 family 51 subfamily A member 1
chr9_+_128340474 0.71 ENST00000300456.5
SLC27A4
solute carrier family 27 member 4
chr8_-_61646807 0.70 ENST00000522919.5
ASPH
aspartate beta-hydroxylase
chr1_+_108876973 0.70 ENST00000441735.2
ENST00000435987.5
ENST00000642355.1
ENST00000645164.2
ENST00000264126.9
ENST00000674914.1
ENST00000643094.1
ENST00000674700.1
GPSM2
G protein signaling modulator 2
chr7_+_93921720 0.69 ENST00000248564.6
GNG11
G protein subunit gamma 11
chr3_+_101827982 0.69 ENST00000461724.5
ENST00000483180.5
ENST00000394054.6
NFKBIZ
NFKB inhibitor zeta
chr1_+_154429315 0.69 ENST00000476006.5
IL6R
interleukin 6 receptor
chr12_-_54259531 0.69 ENST00000550411.5
ENST00000439541.6
CBX5
chromobox 5
chr8_+_12104389 0.69 ENST00000400085.7
ZNF705D
zinc finger protein 705D
chr12_-_86256267 0.69 ENST00000620241.4
MGAT4C
MGAT4 family member C
chrX_-_101617921 0.69 ENST00000361910.9
ENST00000538627.5
ENST00000539247.5
ARMCX6
armadillo repeat containing X-linked 6
chr11_-_105139750 0.68 ENST00000530950.2
CARD18
caspase recruitment domain family member 18
chr7_+_134866831 0.67 ENST00000435928.1
CALD1
caldesmon 1
chr4_-_159035226 0.66 ENST00000434826.3
C4orf45
chromosome 4 open reading frame 45
chr2_-_24328113 0.66 ENST00000622089.4
ITSN2
intersectin 2
chr1_-_99766620 0.66 ENST00000646001.2
FRRS1
ferric chelate reductase 1
chr8_+_11809135 0.65 ENST00000528643.5
ENST00000525777.5
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr6_-_116829037 0.64 ENST00000368549.7
ENST00000530250.1
ENST00000310357.8
GPRC6A
G protein-coupled receptor class C group 6 member A
chr10_+_88594746 0.64 ENST00000531458.1
LIPJ
lipase family member J
chr1_+_178341445 0.64 ENST00000462775.5
RASAL2
RAS protein activator like 2
chr12_+_96912517 0.64 ENST00000457368.2
NEDD1
NEDD1 gamma-tubulin ring complex targeting factor
chr6_+_116399395 0.64 ENST00000644499.1
ENSG00000285446.1
novel protein
chr12_-_21910853 0.64 ENST00000544039.5
ABCC9
ATP binding cassette subfamily C member 9
chr3_-_51779187 0.64 ENST00000398780.5
ENST00000668964.1
ENST00000667863.2
ENST00000647442.1
IQCF6
IQ motif containing F6
chr3_-_197183806 0.63 ENST00000671246.1
ENST00000660553.1
DLG1
discs large MAGUK scaffold protein 1
chr9_+_102995308 0.63 ENST00000612124.4
ENST00000374798.8
ENST00000487798.5
CYLC2
cylicin 2
chr7_+_18495723 0.63 ENST00000681950.1
ENST00000622668.4
ENST00000405010.7
ENST00000406451.8
ENST00000441542.7
ENST00000428307.6
ENST00000681273.1
HDAC9
histone deacetylase 9
chr2_-_224947030 0.63 ENST00000409592.7
DOCK10
dedicator of cytokinesis 10
chr3_-_167474026 0.62 ENST00000466903.1
ENST00000264677.8
SERPINI2
serpin family I member 2
chr18_+_50375037 0.62 ENST00000398452.6
ENST00000417656.6
ENST00000488454.5
ENST00000285116.8
ENST00000494518.1
SKA1
spindle and kinetochore associated complex subunit 1
chr11_+_5389377 0.61 ENST00000328611.5
OR51M1
olfactory receptor family 51 subfamily M member 1
chr10_-_93482326 0.61 ENST00000359263.9
MYOF
myoferlin
chr18_+_74499939 0.60 ENST00000584768.5
CNDP2
carnosine dipeptidase 2
chr3_-_197226351 0.60 ENST00000656428.1
DLG1
discs large MAGUK scaffold protein 1
chrX_-_132961390 0.60 ENST00000370836.6
ENST00000521489.5
HS6ST2
heparan sulfate 6-O-sulfotransferase 2
chr10_+_119819244 0.60 ENST00000637174.1
INPP5F
inositol polyphosphate-5-phosphatase F
chrX_+_37780049 0.59 ENST00000378588.5
CYBB
cytochrome b-245 beta chain
chr8_+_22995831 0.59 ENST00000522948.5
RHOBTB2
Rho related BTB domain containing 2
chr9_+_94084458 0.59 ENST00000620992.5
ENST00000288976.3
PTPDC1
protein tyrosine phosphatase domain containing 1
chr13_-_46142834 0.59 ENST00000674665.1
LCP1
lymphocyte cytosolic protein 1
chrX_+_12906639 0.58 ENST00000311912.5
TLR8
toll like receptor 8
chr13_+_32031706 0.58 ENST00000542859.6
FRY
FRY microtubule binding protein
chr12_-_84911178 0.58 ENST00000681688.1
SLC6A15
solute carrier family 6 member 15
chr11_+_111255982 0.57 ENST00000637637.1
C11orf53
chromosome 11 open reading frame 53
chr6_-_132659178 0.57 ENST00000275216.3
TAAR1
trace amine associated receptor 1
chr1_+_50103903 0.57 ENST00000371827.5
ELAVL4
ELAV like RNA binding protein 4
chr4_-_70666492 0.57 ENST00000254801.9
ENST00000391614.7
JCHAIN
joining chain of multimeric IgA and IgM
chr14_+_32329256 0.57 ENST00000280979.9
AKAP6
A-kinase anchoring protein 6
chr3_+_98166696 0.56 ENST00000641450.1
OR5H15
olfactory receptor family 5 subfamily H member 15
chr3_+_189631373 0.56 ENST00000264731.8
ENST00000418709.6
ENST00000320472.9
ENST00000392460.7
ENST00000440651.6
TP63
tumor protein p63
chr9_+_706841 0.56 ENST00000382293.7
KANK1
KN motif and ankyrin repeat domains 1
chr5_+_55102635 0.56 ENST00000274306.7
GZMA
granzyme A
chr2_-_210303608 0.54 ENST00000341685.8
MYL1
myosin light chain 1
chr1_-_38876351 0.54 ENST00000360786.3
GJA9
gap junction protein alpha 9
chr6_-_65707214 0.54 ENST00000370621.7
ENST00000393380.6
ENST00000503581.6
EYS
eyes shut homolog
chr20_+_31547367 0.54 ENST00000394552.3
MCTS2P
MCTS family member 2, pseudogene
chr11_+_111245725 0.54 ENST00000280325.7
C11orf53
chromosome 11 open reading frame 53
chr5_+_137867852 0.53 ENST00000421631.6
ENST00000239926.9
MYOT
myotilin
chr6_-_32407123 0.53 ENST00000374993.4
ENST00000544175.2
ENST00000454136.7
ENST00000446536.2
BTNL2
butyrophilin like 2
chr5_-_151924846 0.53 ENST00000274576.9
GLRA1
glycine receptor alpha 1
chr8_+_38728550 0.53 ENST00000520340.5
ENST00000518415.5
TACC1
transforming acidic coiled-coil containing protein 1
chr14_-_106593319 0.52 ENST00000390627.3
IGHV3-53
immunoglobulin heavy variable 3-53
chr5_-_126595185 0.52 ENST00000510111.6
ENST00000635851.1
ENST00000637964.1
ENST00000413020.6
ENST00000637782.1
ENST00000409134.8
ENST00000637272.1
ENST00000636879.1
ENST00000636743.1
ENST00000636886.1
ENST00000509270.2
ALDH7A1
aldehyde dehydrogenase 7 family member A1
chr8_-_94262308 0.52 ENST00000297596.3
ENST00000396194.6
GEM
GTP binding protein overexpressed in skeletal muscle
chr12_+_71664352 0.51 ENST00000547843.1
THAP2
THAP domain containing 2
chr9_-_21482313 0.51 ENST00000448696.4
IFNE
interferon epsilon
chr9_-_92424427 0.51 ENST00000375550.5
OMD
osteomodulin
chr5_-_151924824 0.51 ENST00000455880.2
GLRA1
glycine receptor alpha 1
chr17_-_82840010 0.51 ENST00000269394.4
ENST00000572562.1
ZNF750
zinc finger protein 750
chr3_+_159069252 0.50 ENST00000640015.1
ENST00000476809.7
ENST00000485419.7
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr18_+_616672 0.50 ENST00000338387.11
CLUL1
clusterin like 1
chr17_-_66220630 0.50 ENST00000585162.1
APOH
apolipoprotein H
chrX_+_108045050 0.50 ENST00000458383.1
ENST00000217957.10
VSIG1
V-set and immunoglobulin domain containing 1
chr5_-_88731827 0.50 ENST00000627170.2
MEF2C
myocyte enhancer factor 2C
chr8_-_673547 0.50 ENST00000522893.1
ERICH1
glutamate rich 1
chr1_+_67166448 0.49 ENST00000347310.10
IL23R
interleukin 23 receptor
chr11_-_122116215 0.49 ENST00000560104.2
BLID
BH3-like motif containing, cell death inducer
chr3_+_26694499 0.49 ENST00000456208.2
LRRC3B
leucine rich repeat containing 3B
chrX_+_41689006 0.49 ENST00000378138.5
ENST00000620846.1
ENST00000649219.1
GPR34
G protein-coupled receptor 34
chr8_+_54616078 0.48 ENST00000220676.2
RP1
RP1 axonemal microtubule associated
chr2_+_135586250 0.48 ENST00000410054.5
ENST00000628915.2
R3HDM1
R3H domain containing 1
chr9_-_42129125 0.48 ENST00000617422.4
ENST00000612828.4
ENST00000341990.8
ENST00000377561.7
ENST00000276974.7
CNTNAP3B
contactin associated protein family member 3B

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 1.8 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.8 2.4 GO:0045062 extrathymic T cell selection(GO:0045062)
0.8 2.3 GO:0060279 positive regulation of ovulation(GO:0060279)
0.6 1.8 GO:0060623 regulation of chromosome condensation(GO:0060623) cellular response to iron(III) ion(GO:0071283)
0.6 1.7 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.4 0.8 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.4 1.6 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.4 6.1 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764)
0.4 2.3 GO:0010749 regulation of nitric oxide mediated signal transduction(GO:0010749) negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.4 1.5 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.4 1.5 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.4 1.4 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.3 2.0 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) positive regulation of interleukin-12 secretion(GO:2001184)
0.3 6.0 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.3 1.3 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.3 0.9 GO:0061182 negative regulation of chondrocyte development(GO:0061182)
0.3 1.8 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.3 2.0 GO:0097338 response to clozapine(GO:0097338)
0.3 1.9 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.2 1.0 GO:0006175 adenosine salvage(GO:0006169) dATP biosynthetic process(GO:0006175)
0.2 2.7 GO:0035524 proline transmembrane transport(GO:0035524)
0.2 0.7 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.2 0.9 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.2 0.9 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.2 1.3 GO:0006543 glutamine catabolic process(GO:0006543)
0.2 1.7 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.2 0.8 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.2 0.6 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.2 0.8 GO:0090096 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.2 1.0 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.2 0.8 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.2 2.3 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.2 1.7 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.2 1.8 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.2 0.7 GO:0002384 hepatic immune response(GO:0002384)
0.2 0.5 GO:0009085 lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878)
0.1 0.6 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.1 1.0 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 0.4 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199) negative regulation of icosanoid secretion(GO:0032304)
0.1 1.7 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.1 0.7 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.6 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 0.6 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1 0.7 GO:0031291 Ran protein signal transduction(GO:0031291)
0.1 0.4 GO:0072275 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.1 0.9 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1 0.4 GO:0052331 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.1 0.8 GO:0010966 regulation of phosphate transport(GO:0010966)
0.1 0.5 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 1.0 GO:1904304 regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306)
0.1 7.6 GO:0018149 peptide cross-linking(GO:0018149)
0.1 0.5 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.1 0.4 GO:0048058 compound eye corneal lens development(GO:0048058)
0.1 0.7 GO:0051622 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1 0.6 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 1.3 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.3 GO:1901877 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.1 1.3 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1 0.6 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 0.3 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.1 0.8 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.1 0.9 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 0.1 GO:0060278 regulation of ovulation(GO:0060278)
0.1 1.7 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.3 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 1.3 GO:0007144 female meiosis I(GO:0007144)
0.1 0.5 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1 0.3 GO:0009106 lipoate metabolic process(GO:0009106)
0.1 0.8 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.3 GO:0097534 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.1 0.4 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.1 0.2 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.1 0.2 GO:0060931 sinoatrial node cell development(GO:0060931)
0.1 0.2 GO:0006533 aspartate catabolic process(GO:0006533)
0.1 0.2 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.1 0.3 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.3 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 1.6 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 0.5 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.4 GO:0043382 positive regulation of memory T cell differentiation(GO:0043382)
0.1 0.3 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
0.1 0.3 GO:1990523 bone regeneration(GO:1990523)
0.1 0.4 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.1 0.8 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 0.2 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.1 1.0 GO:0033327 Leydig cell differentiation(GO:0033327) response to UV-A(GO:0070141)
0.1 0.2 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.1 1.8 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.1 0.4 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 0.4 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.1 0.4 GO:0001880 Mullerian duct regression(GO:0001880)
0.1 0.9 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.4 GO:0019060 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.1 0.1 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.1 0.9 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.1 0.6 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.1 0.3 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.1 0.4 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005) collateral sprouting in absence of injury(GO:0048669) smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563) cellular response to norepinephrine stimulus(GO:0071874)
0.1 1.0 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.1 0.1 GO:0009946 proximal/distal axis specification(GO:0009946)
0.1 0.3 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.1 1.3 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1 0.7 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.1 0.4 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.1 0.2 GO:0071206 establishment of protein localization to juxtaparanode region of axon(GO:0071206)
0.1 0.4 GO:0002329 pre-B cell differentiation(GO:0002329)
0.1 1.0 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 1.0 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 0.2 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.3 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.1 0.2 GO:1903487 regulation of lactation(GO:1903487)
0.1 0.5 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.1 0.4 GO:0019236 response to pheromone(GO:0019236)
0.1 0.6 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.1 0.2 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 4.9 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 0.6 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.1 0.7 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.1 0.7 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.1 0.8 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 0.4 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.2 GO:0097325 melanocyte proliferation(GO:0097325)
0.0 0.4 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 1.8 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.8 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.4 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 1.2 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.1 GO:0060739 mesenchymal-epithelial cell signaling involved in prostate gland development(GO:0060739)
0.0 0.0 GO:0045608 inhibition of neuroepithelial cell differentiation(GO:0002085) negative regulation of auditory receptor cell differentiation(GO:0045608)
0.0 0.3 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.6 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.2 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.0 0.7 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.6 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.3 GO:0060536 cartilage morphogenesis(GO:0060536)
0.0 0.2 GO:0007538 primary sex determination(GO:0007538)
0.0 0.5 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.2 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.5 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.3 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.1 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 0.2 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.4 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.2 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 4.0 GO:0070268 cornification(GO:0070268)
0.0 0.2 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.4 GO:2000580 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:0021502 neural fold elevation formation(GO:0021502)
0.0 0.2 GO:0048840 otolith development(GO:0048840)
0.0 0.3 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.6 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.4 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 1.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.4 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 5.8 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.5 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.1 GO:1903973 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973) regulation of microglial cell activation(GO:1903978)
0.0 0.2 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.8 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 1.2 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.4 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.3 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.2 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.4 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.2 GO:0044791 receptor-mediated endocytosis of virus by host cell(GO:0019065) modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 0.7 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.5 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0032571 response to vitamin K(GO:0032571)
0.0 0.1 GO:0046533 negative regulation of photoreceptor cell differentiation(GO:0046533)
0.0 1.4 GO:0031424 keratinization(GO:0031424)
0.0 0.5 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 2.8 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.9 GO:0033189 response to vitamin A(GO:0033189)
0.0 1.0 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.2 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.5 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 0.6 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.1 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.1 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.4 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.0 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.2 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.0 0.3 GO:0019530 taurine metabolic process(GO:0019530)
0.0 0.5 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 1.1 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 1.0 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.6 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 2.1 GO:2000177 regulation of neural precursor cell proliferation(GO:2000177)
0.0 0.1 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 0.2 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0 1.0 GO:0097435 fibril organization(GO:0097435)
0.0 0.2 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.2 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.2 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.4 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.4 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.0 0.1 GO:0060297 regulation of sarcomere organization(GO:0060297)
0.0 0.5 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 0.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.2 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.1 GO:0032930 positive regulation of superoxide anion generation(GO:0032930)
0.0 0.2 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.2 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.4 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.0 0.9 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.1 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.8 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.2 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.0 0.2 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.2 GO:0002097 tRNA wobble base modification(GO:0002097)
0.0 0.2 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.1 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 2.1 GO:0030010 establishment of cell polarity(GO:0030010)
0.0 0.7 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.2 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.1 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.0 0.1 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.7 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.2 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.0 0.2 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.2 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:0007113 endomitotic cell cycle(GO:0007113)
0.0 0.1 GO:0070170 regulation of tooth mineralization(GO:0070170)
0.0 0.1 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.6 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 1.9 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.1 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.2 GO:0009650 UV protection(GO:0009650)
0.0 0.1 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.5 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.9 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.1 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.2 GO:0097264 self proteolysis(GO:0097264)
0.0 0.2 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.2 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.4 1.8 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.4 2.6 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.4 2.3 GO:0097149 centralspindlin complex(GO:0097149)
0.3 5.9 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.2 11.4 GO:0001533 cornified envelope(GO:0001533)
0.2 0.6 GO:0071750 dimeric IgA immunoglobulin complex(GO:0071750) secretory dimeric IgA immunoglobulin complex(GO:0071752) IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
0.2 2.7 GO:0030478 actin cap(GO:0030478)
0.1 0.4 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.4 GO:0033150 cytoskeletal calyx(GO:0033150)
0.1 1.7 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.7 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 1.8 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 1.9 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.4 GO:0097679 other organism cytoplasm(GO:0097679)
0.1 0.5 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.1 0.3 GO:0034515 proteasome storage granule(GO:0034515)
0.1 1.1 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1 2.0 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.4 GO:0071942 XPC complex(GO:0071942)
0.1 1.1 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.2 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 0.4 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.1 0.4 GO:0002079 inner acrosomal membrane(GO:0002079)
0.1 0.7 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 0.2 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.1 1.0 GO:0008091 spectrin(GO:0008091)
0.1 0.4 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 1.2 GO:0031045 dense core granule(GO:0031045)
0.0 0.4 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.2 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.8 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.8 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.4 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.2 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.4 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 0.9 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.3 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 1.0 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 1.0 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.3 GO:0070852 cell body fiber(GO:0070852)
0.0 0.2 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 1.5 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.9 GO:0042627 chylomicron(GO:0042627)
0.0 0.3 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 0.5 GO:0051233 spindle midzone(GO:0051233)
0.0 0.3 GO:0060091 kinocilium(GO:0060091)
0.0 0.8 GO:0010369 chromocenter(GO:0010369)
0.0 6.1 GO:0000922 spindle pole(GO:0000922)
0.0 0.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.5 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 1.7 GO:0097610 cell division site(GO:0032153) cleavage furrow(GO:0032154) cell division site part(GO:0032155) cell surface furrow(GO:0097610)
0.0 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.0 4.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.9 GO:0005859 muscle myosin complex(GO:0005859)
0.0 2.6 GO:0005604 basement membrane(GO:0005604)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.4 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 2.0 GO:0043195 terminal bouton(GO:0043195)
0.0 0.6 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.9 GO:0001772 immunological synapse(GO:0001772)
0.0 0.4 GO:0005922 connexon complex(GO:0005922)
0.0 2.3 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.4 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.2 GO:0098644 complex of collagen trimers(GO:0098644)
0.0 0.1 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 1.8 GO:0005901 caveola(GO:0005901)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0005960 glycine cleavage complex(GO:0005960)
0.0 1.1 GO:0045095 keratin filament(GO:0045095)
0.0 1.3 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 2.1 GO:0016605 PML body(GO:0016605)
0.0 0.3 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.5 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0016011 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0 1.1 GO:0005882 intermediate filament(GO:0005882)
0.0 0.4 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.2 GO:0016013 syntrophin complex(GO:0016013)
0.0 3.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0061574 ASAP complex(GO:0061574)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.2 GO:0017161 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.6 1.9 GO:0042008 interleukin-33 binding(GO:0002113) interleukin-18 receptor activity(GO:0042008)
0.4 2.7 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.4 6.1 GO:0097016 L27 domain binding(GO:0097016)
0.3 1.8 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.3 2.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.3 3.6 GO:0030280 structural constituent of epidermis(GO:0030280)
0.2 1.0 GO:0004001 adenosine kinase activity(GO:0004001)
0.2 0.7 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.2 0.7 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.2 1.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.2 1.3 GO:0004359 glutaminase activity(GO:0004359)
0.2 4.0 GO:0008179 adenylate cyclase binding(GO:0008179)
0.2 1.0 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.2 0.6 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.2 0.6 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.2 5.5 GO:0005549 odorant binding(GO:0005549)
0.2 2.0 GO:0051525 NFAT protein binding(GO:0051525)
0.2 0.9 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.2 0.7 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.2 0.6 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.2 0.8 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.2 0.9 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.2 0.5 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.1 0.4 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 1.1 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.4 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.4 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 0.9 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.5 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.1 0.7 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 2.0 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.6 GO:0019862 IgA binding(GO:0019862)
0.1 0.6 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.7 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 2.7 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.4 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 1.7 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.9 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.1 1.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 0.4 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 0.3 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.1 0.3 GO:0052815 medium-chain acyl-CoA hydrolase activity(GO:0052815) long-chain acyl-CoA hydrolase activity(GO:0052816)
0.1 0.8 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 1.3 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 0.5 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.1 1.7 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 0.4 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 0.6 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1 0.8 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 0.4 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 1.1 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.4 GO:0004370 glycerol kinase activity(GO:0004370)
0.1 1.6 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.3 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.7 GO:0089720 caspase binding(GO:0089720)
0.1 0.5 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 0.4 GO:0031013 troponin I binding(GO:0031013)
0.1 0.4 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.1 0.5 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.8 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 1.6 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.8 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 3.7 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.2 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.1 0.3 GO:0047086 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.0 0.7 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.3 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.6 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.4 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 5.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.7 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.8 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.2 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.3 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.3 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.9 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 1.5 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.9 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.2 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.0 0.6 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 1.1 GO:0070064 proline-rich region binding(GO:0070064)
0.0 1.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 1.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.2 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.0 0.7 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.5 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.4 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.4 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 1.4 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 1.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 2.9 GO:0005179 hormone activity(GO:0005179)
0.0 0.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.5 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 4.0 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 4.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0033265 choline binding(GO:0033265)
0.0 0.3 GO:0042301 phosphate ion binding(GO:0042301)
0.0 1.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.8 GO:0042805 actinin binding(GO:0042805)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.4 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.6 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.2 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.8 GO:0000146 microfilament motor activity(GO:0000146)
0.0 2.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.6 GO:0030552 cAMP binding(GO:0030552)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 0.4 GO:0032183 SUMO binding(GO:0032183)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.1 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.0 0.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.3 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 2.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.5 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.1 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.9 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.1 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.9 GO:0005518 collagen binding(GO:0005518)
0.0 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.4 GO:0001848 complement binding(GO:0001848)
0.0 1.1 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.5 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.2 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 2.6 GO:0051015 actin filament binding(GO:0051015)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 2.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 1.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 7.0 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 3.1 PID IL23 PATHWAY IL23-mediated signaling events
0.1 2.7 PID ALK1 PATHWAY ALK1 signaling events
0.1 4.0 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 0.7 ST STAT3 PATHWAY STAT3 Pathway
0.0 2.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 3.6 PID LKB1 PATHWAY LKB1 signaling events
0.0 3.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 3.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 2.1 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 2.2 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.9 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 1.3 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 2.7 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.3 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.6 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.0 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.4 PID IGF1 PATHWAY IGF1 pathway
0.0 1.5 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.6 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.6 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 1.0 PID PLK1 PATHWAY PLK1 signaling events
0.0 5.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.4 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.5 PID AURORA A PATHWAY Aurora A signaling
0.0 0.8 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.2 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.1 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.1 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.3 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.1 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.2 4.9 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.2 3.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.2 6.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 2.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 2.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 1.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 2.0 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 2.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 1.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 2.1 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 0.8 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 2.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.0 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.6 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 2.0 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.9 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 1.5 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.0 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.0 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 0.7 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.1 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.9 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 5.5 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.9 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 1.3 REACTOME KINESINS Genes involved in Kinesins
0.0 0.8 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.6 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.2 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.6 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.9 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.0 1.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.2 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.2 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 1.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.1 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.6 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.8 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 1.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.6 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.3 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.0 0.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.3 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.4 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 1.0 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.5 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.4 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.4 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 1.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.7 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.6 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 1.8 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.5 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.4 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.6 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 1.0 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.0 0.4 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 1.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.5 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4