ISMARA results: HMX2

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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for HMX2

Z-value: 0.49

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Transcription factors associated with HMX2

Gene Symbol	Gene ID	Gene Info
HMX2 Ensembl NCBI GeneCards UniProt	ENSG00000188816.4	HMX2

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
HMX2	hg38_v1_chr10_+_123148128_123148145	0.20	3.0e-01	Click!

Activity profile of HMX2 motif

Sorted Z-values of HMX2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HMX2

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View png image

Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr19_+_57633161 Show fit	0.74	ENST00000541801.5 ENST00000347302.7 ENST00000240731.5 ENST00000254182.11 ENST00000391703.3	ZNF211 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 211
chr6_-_32668368 Show fit	0.64	ENST00000399084.5	HLA-DQB1 Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class II, DQ beta 1
chr11_+_118533032 Show fit	0.50	ENST00000526853.1	TMEM25 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 25
chr18_+_63702958 Show fit	0.49	ENST00000544088.6	SERPINB11 Ensembl NCBI GeneCards UniProt Show fit	serpin family B member 11
chr3_+_155083889 Show fit	0.47	ENST00000680282.1	MME Ensembl NCBI GeneCards UniProt Show fit	membrane metalloendopeptidase
chr13_-_61427849 Show fit	0.45	ENST00000409186.1 ENST00000472649.2	ENSG00000197991.11 Ensembl NCBI GeneCards UniProt Show fit LINC02339 Ensembl NCBI GeneCards UniProt Show fit	novel protein long intergenic non-protein coding RNA 2339
chr6_-_27890818 Show fit	0.43	ENST00000359303.4	H3C12 Ensembl NCBI GeneCards UniProt Show fit	H3 clustered histone 12
chr1_+_248445512 Show fit	0.41	ENST00000642130.1 ENST00000641925.2	OR2T2 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 2 subfamily T member 2
chr1_+_209704836 Show fit	0.40	ENST00000367027.5	HSD11B1 Ensembl NCBI GeneCards UniProt Show fit	hydroxysteroid 11-beta dehydrogenase 1
chr17_+_9825906 Show fit	0.40	ENST00000262441.10	GLP2R Ensembl NCBI GeneCards UniProt Show fit	glucagon like peptide 2 receptor
chr18_+_44680875 Show fit	0.38	ENST00000649279.2 ENST00000677699.1	SETBP1 Ensembl NCBI GeneCards UniProt Show fit	SET binding protein 1
chr9_+_27109393 Show fit	0.37	ENST00000406359.8	TEK Ensembl NCBI GeneCards UniProt Show fit	TEK receptor tyrosine kinase
chr17_-_31314066 Show fit	0.36	ENST00000577894.1	EVI2B Ensembl NCBI GeneCards UniProt Show fit	ecotropic viral integration site 2B
chr15_+_40764055 Show fit	0.34	ENST00000260447.6 ENST00000561160.1 ENST00000558670.1 ENST00000559445.1	GCHFR Ensembl NCBI GeneCards UniProt Show fit	GTP cyclohydrolase I feedback regulator
chr1_-_151831768 Show fit	0.33	ENST00000318247.7	RORC Ensembl NCBI GeneCards UniProt Show fit	RAR related orphan receptor C
chr2_+_210477708 Show fit	0.31	ENST00000673711.1	CPS1 Ensembl NCBI GeneCards UniProt Show fit	carbamoyl-phosphate synthase 1
chr2_-_159798234 Show fit	0.30	ENST00000429078.6 ENST00000553424.5	CD302 Ensembl NCBI GeneCards UniProt Show fit	CD302 molecule
chr10_-_119536533 Show fit	0.30	ENST00000392865.5	RGS10 Ensembl NCBI GeneCards UniProt Show fit	regulator of G protein signaling 10
chr2_+_210477676 Show fit	0.29	ENST00000673510.1 ENST00000673630.1 ENST00000430249.7	CPS1 Ensembl NCBI GeneCards UniProt Show fit	carbamoyl-phosphate synthase 1
chr1_-_205321737 Show fit	0.28	ENST00000367157.6	NUAK2 Ensembl NCBI GeneCards UniProt Show fit	NUAK family kinase 2
chr2_-_159798043 Show fit	0.27	ENST00000664982.1 ENST00000259053.6	ENSG00000287091.1 Ensembl NCBI GeneCards UniProt Show fit CD302 Ensembl NCBI GeneCards UniProt Show fit	novel transcript, sense intronic to CD302and LY75-CD302 CD302 molecule
chr4_-_69653223 Show fit	0.26	ENST00000286604.8 ENST00000505512.1 ENST00000514019.1	UGT2A1 Ensembl NCBI GeneCards UniProt Show fit	UDP glucuronosyltransferase family 2 member A1 complex locus
chr11_+_7597182 Show fit	0.26	ENST00000528883.5	PPFIBP2 Ensembl NCBI GeneCards UniProt Show fit	PPFIA binding protein 2
chrX_+_106693838 Show fit	0.26	ENST00000324342.7	RNF128 Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 128
chr17_-_445939 Show fit	0.25	ENST00000329099.4	RFLNB Ensembl NCBI GeneCards UniProt Show fit	refilin B
chr3_-_121660892 Show fit	0.24	ENST00000428394.6 ENST00000314583.8	HCLS1 Ensembl NCBI GeneCards UniProt Show fit	hematopoietic cell-specific Lyn substrate 1
chr13_-_48413105 Show fit	0.23	ENST00000620633.5	LPAR6 Ensembl NCBI GeneCards UniProt Show fit	lysophosphatidic acid receptor 6
chr4_+_25914275 Show fit	0.23	ENST00000514384.1	SMIM20 Ensembl NCBI GeneCards UniProt Show fit	small integral membrane protein 20
chr1_+_119711884 Show fit	0.22	ENST00000641947.1 ENST00000641074.1 ENST00000641115.1 ENST00000369409.9 ENST00000641023.2 ENST00000641272.1	PHGDH Ensembl NCBI GeneCards UniProt Show fit	phosphoglycerate dehydrogenase
chr8_-_92966081 Show fit	0.22	ENST00000517858.5 ENST00000378861.9	TRIQK Ensembl NCBI GeneCards UniProt Show fit	triple QxxK/R motif containing
chr6_+_25652272 Show fit	0.22	ENST00000334979.6	SCGN Ensembl NCBI GeneCards UniProt Show fit	secretagogin, EF-hand calcium binding protein
chr6_+_26124161 Show fit	0.22	ENST00000377791.4 ENST00000602637.1	H2AC6 Ensembl NCBI GeneCards UniProt Show fit	H2A clustered histone 6
chr4_+_25914171 Show fit	0.22	ENST00000506197.2	SMIM20 Ensembl NCBI GeneCards UniProt Show fit	small integral membrane protein 20
chrX_+_72776873 Show fit	0.21	ENST00000334036.10	DMRTC1B Ensembl NCBI GeneCards UniProt Show fit	DMRT like family C1B
chr6_+_151239951 Show fit	0.21	ENST00000402676.7	AKAP12 Ensembl NCBI GeneCards UniProt Show fit	A-kinase anchoring protein 12
chrX_-_72943837 Show fit	0.21	ENST00000615063.2	DMRTC1 Ensembl NCBI GeneCards UniProt Show fit	DMRT like family C1
chr16_-_67483541 Show fit	0.21	ENST00000290953.3	AGRP Ensembl NCBI GeneCards UniProt Show fit	agouti related neuropeptide
chr7_-_7640971 Show fit	0.20	ENST00000396682.6	RPA3 Ensembl NCBI GeneCards UniProt Show fit	replication protein A3
chr22_-_16825404 Show fit	0.20	ENST00000684488.1	XKR3 Ensembl NCBI GeneCards UniProt Show fit	XK related 3
chr4_-_137532452 Show fit	0.20	ENST00000412923.6 ENST00000511115.5 ENST00000344876.9 ENST00000507846.5 ENST00000510305.5 ENST00000611581.1	PCDH18 Ensembl NCBI GeneCards UniProt Show fit	protocadherin 18
chr3_-_149221811 Show fit	0.19	ENST00000455472.3 ENST00000264613.11	CP Ensembl NCBI GeneCards UniProt Show fit	ceruloplasmin
chr2_+_108378176 Show fit	0.19	ENST00000409309.3	SULT1C4 Ensembl NCBI GeneCards UniProt Show fit	sulfotransferase family 1C member 4
chr8_-_92966105 Show fit	0.19	ENST00000524037.5 ENST00000520430.5 ENST00000521617.5 ENST00000523580.5	TRIQK Ensembl NCBI GeneCards UniProt Show fit	triple QxxK/R motif containing
chr11_+_64234569 Show fit	0.19	ENST00000309422.7 ENST00000426086.3	VEGFB Ensembl NCBI GeneCards UniProt Show fit	vascular endothelial growth factor B
chr1_+_33081145 Show fit	0.19	ENST00000294517.11 ENST00000373443.7	AZIN2 Ensembl NCBI GeneCards UniProt Show fit	antizyme inhibitor 2
chr6_-_26199272 Show fit	0.19	ENST00000650491.1 ENST00000635200.1 ENST00000341023.2	ENSG00000282988.2 Ensembl NCBI GeneCards UniProt Show fit H2AC7 Ensembl NCBI GeneCards UniProt Show fit	novel protein H2A clustered histone 7
chr9_+_96928310 Show fit	0.18	ENST00000354649.7	NUTM2G Ensembl NCBI GeneCards UniProt Show fit	NUT family member 2G
chr6_-_151452096 Show fit	0.18	ENST00000444024.3 ENST00000682641.1 ENST00000682299.1 ENST00000622845.5	RMND1 Ensembl NCBI GeneCards UniProt Show fit	required for meiotic nuclear division 1 homolog
chr4_-_39032922 Show fit	0.18	ENST00000344606.6	TMEM156 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 156
chr11_+_122882683 Show fit	0.18	ENST00000307257.10 ENST00000227349.7	JHY Ensembl NCBI GeneCards UniProt Show fit	junctional cadherin complex regulator
chr17_+_69502397 Show fit	0.17	ENST00000613873.4 ENST00000589647.5	MAP2K6 Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase kinase 6
chr6_-_151452018 Show fit	0.17	ENST00000491268.2	RMND1 Ensembl NCBI GeneCards UniProt Show fit	required for meiotic nuclear division 1 homolog
chr1_-_107688492 Show fit	0.16	ENST00000415432.6	VAV3 Ensembl NCBI GeneCards UniProt Show fit	vav guanine nucleotide exchange factor 3
chr10_-_5003850 Show fit	0.16	ENST00000421196.7 ENST00000455190.2 ENST00000380753.8	AKR1C2 Ensembl NCBI GeneCards UniProt Show fit	aldo-keto reductase family 1 member C2
chr6_+_85449584 Show fit	0.16	ENST00000369651.7	NT5E Ensembl NCBI GeneCards UniProt Show fit	5'-nucleotidase ecto
chr3_+_123067016 Show fit	0.16	ENST00000316218.12	PDIA5 Ensembl NCBI GeneCards UniProt Show fit	protein disulfide isomerase family A member 5
chrX_-_101932074 Show fit	0.16	ENST00000651725.1	ZMAT1 Ensembl NCBI GeneCards UniProt Show fit	zinc finger matrin-type 1
chr1_+_98661666 Show fit	0.15	ENST00000529992.5	SNX7 Ensembl NCBI GeneCards UniProt Show fit	sorting nexin 7
chr10_-_60141004 Show fit	0.15	ENST00000355288.6	ANK3 Ensembl NCBI GeneCards UniProt Show fit	ankyrin 3
chr12_-_71663791 Show fit	0.15	ENST00000548100.1	ZFC3H1 Ensembl NCBI GeneCards UniProt Show fit	zinc finger C3H1-type containing
chr19_-_43880142 Show fit	0.15	ENST00000324394.7	ZNF404 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 404
chr2_+_157257687 Show fit	0.15	ENST00000259056.5	GALNT5 Ensembl NCBI GeneCards UniProt Show fit	polypeptide N-acetylgalactosaminyltransferase 5
chr3_-_138329839 Show fit	0.15	ENST00000333911.9 ENST00000383180.6	NME9 Ensembl NCBI GeneCards UniProt Show fit	NME/NM23 family member 9
chr16_-_86555021 Show fit	0.15	ENST00000565482.1 ENST00000564364.5 ENST00000561989.5 ENST00000568037.5 ENST00000634347.1 ENST00000543303.6 ENST00000381214.9 ENST00000360900.11 ENST00000546093.5 ENST00000569000.5 ENST00000562994.5 ENST00000561522.1	MTHFSD Ensembl NCBI GeneCards UniProt Show fit	methenyltetrahydrofolate synthetase domain containing
chr19_-_7058640 Show fit	0.14	ENST00000333843.8	MBD3L3 Ensembl NCBI GeneCards UniProt Show fit	methyl-CpG binding domain protein 3 like 3
chr12_+_81078035 Show fit	0.14	ENST00000261206.7 ENST00000548058.6	ACSS3 Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA synthetase short chain family member 3
chr4_-_119322128 Show fit	0.14	ENST00000274024.4	FABP2 Ensembl NCBI GeneCards UniProt Show fit	fatty acid binding protein 2
chr12_+_133037533 Show fit	0.13	ENST00000327668.11	ZNF84 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 84
chr7_+_77696423 Show fit	0.13	ENST00000334955.13	RSBN1L Ensembl NCBI GeneCards UniProt Show fit	round spermatid basic protein 1 like
chr7_-_14841267 Show fit	0.13	ENST00000406247.7 ENST00000399322.7	DGKB Ensembl NCBI GeneCards UniProt Show fit	diacylglycerol kinase beta
chr6_+_63635792 Show fit	0.13	ENST00000262043.8 ENST00000506783.5 ENST00000481385.6 ENST00000515594.5 ENST00000494284.6	PHF3 Ensembl NCBI GeneCards UniProt Show fit	PHD finger protein 3
chrX_+_80420466 Show fit	0.13	ENST00000308293.5	TENT5D Ensembl NCBI GeneCards UniProt Show fit	terminal nucleotidyltransferase 5D
chr8_-_92966129 Show fit	0.12	ENST00000522925.5 ENST00000522903.5 ENST00000537541.1 ENST00000521988.6 ENST00000518748.5 ENST00000519069.5	TRIQK Ensembl NCBI GeneCards UniProt Show fit	triple QxxK/R motif containing
chr19_-_52171643 Show fit	0.12	ENST00000597065.1	ZNF836 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 836
chr1_+_108560031 Show fit	0.12	ENST00000405454.1 ENST00000370035.8	FAM102B Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 102 member B
chr6_-_26123910 Show fit	0.12	ENST00000314332.5 ENST00000396984.1	H2BC4 Ensembl NCBI GeneCards UniProt Show fit	H2B clustered histone 4
chr20_+_49812818 Show fit	0.12	ENST00000361573.3	SLC9A8 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 9 member A8
chr8_-_100559702 Show fit	0.12	ENST00000520311.5 ENST00000520552.5 ENST00000521345.1 ENST00000523000.5 ENST00000335659.7 ENST00000358990.3 ENST00000519597.5	ANKRD46 Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat domain 46
chr13_+_27424583 Show fit	0.11	ENST00000381140.10	GTF3A Ensembl NCBI GeneCards UniProt Show fit	general transcription factor IIIA
chr11_-_74731148 Show fit	0.11	ENST00000263671.9 ENST00000528789.1	CHRDL2 Ensembl NCBI GeneCards UniProt Show fit	chordin like 2
chr12_+_25052634 Show fit	0.11	ENST00000548766.5	IRAG2 Ensembl NCBI GeneCards UniProt Show fit	inositol 1,4,5-triphosphate receptor associated 2
chr10_-_97445850 Show fit	0.11	ENST00000477692.6 ENST00000485122.6 ENST00000370886.9 ENST00000370885.8 ENST00000370902.8 ENST00000370884.5	EXOSC1 Ensembl NCBI GeneCards UniProt Show fit	exosome component 1
chr6_+_25754699 Show fit	0.11	ENST00000439485.6 ENST00000377905.9	SLC17A4 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 17 member 4
chr10_-_72215903 Show fit	0.11	ENST00000526751.5 ENST00000672774.1 ENST00000394919.5 ENST00000394915.7	ASCC1 Ensembl NCBI GeneCards UniProt Show fit	activating signal cointegrator 1 complex subunit 1
chr17_-_75667088 Show fit	0.11	ENST00000578201.5 ENST00000423245.6 ENST00000317905.10	RECQL5 Ensembl NCBI GeneCards UniProt Show fit	RecQ like helicase 5
chr17_-_40665121 Show fit	0.11	ENST00000394052.5	KRT222 Ensembl NCBI GeneCards UniProt Show fit	keratin 222
chr10_-_113854069 Show fit	0.11	ENST00000361384.7	DCLRE1A Ensembl NCBI GeneCards UniProt Show fit	DNA cross-link repair 1A
chr5_+_151025343 Show fit	0.11	ENST00000521632.1	GPX3 Ensembl NCBI GeneCards UniProt Show fit	glutathione peroxidase 3
chr5_-_22853320 Show fit	0.10	ENST00000504376.6 ENST00000382254.6	CDH12 Ensembl NCBI GeneCards UniProt Show fit	cadherin 12
chr13_-_35855758 Show fit	0.10	ENST00000615680.4	DCLK1 Ensembl NCBI GeneCards UniProt Show fit	doublecortin like kinase 1
chr3_+_173398438 Show fit	0.10	ENST00000457714.5	NLGN1 Ensembl NCBI GeneCards UniProt Show fit	neuroligin 1
chr15_+_67543178 Show fit	0.10	ENST00000395476.6	MAP2K5 Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase kinase 5
chr11_-_74731385 Show fit	0.10	ENST00000622063.4 ENST00000376332.8	CHRDL2 Ensembl NCBI GeneCards UniProt Show fit	chordin like 2
chr1_+_64203610 Show fit	0.10	ENST00000371077.10 ENST00000611228.4	UBE2U Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 U
chr3_-_186544377 Show fit	0.10	ENST00000307944.6	CRYGS Ensembl NCBI GeneCards UniProt Show fit	crystallin gamma S
chr21_+_30396030 Show fit	0.10	ENST00000355459.4	KRTAP13-1 Ensembl NCBI GeneCards UniProt Show fit	keratin associated protein 13-1
chr2_-_200510044 Show fit	0.10	ENST00000359878.8 ENST00000409157.5	KCTD18 Ensembl NCBI GeneCards UniProt Show fit	potassium channel tetramerization domain containing 18
chr10_-_48605032 Show fit	0.10	ENST00000249601.9	ARHGAP22 Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 22
chr20_+_43507668 Show fit	0.10	ENST00000434666.5 ENST00000649084.1 ENST00000418998.7 ENST00000427442.8 ENST00000649917.1	L3MBTL1 Ensembl NCBI GeneCards UniProt Show fit	L3MBTL histone methyl-lysine binding protein 1
chr7_-_88226965 Show fit	0.10	ENST00000490437.5 ENST00000431660.5	SRI Ensembl NCBI GeneCards UniProt Show fit	sorcin
chr7_+_141995826 Show fit	0.10	ENST00000549489.6	MGAM Ensembl NCBI GeneCards UniProt Show fit	maltase-glucoamylase
chr1_+_196977550 Show fit	0.09	ENST00000256785.5	CFHR5 Ensembl NCBI GeneCards UniProt Show fit	complement factor H related 5
chr4_-_26490453 Show fit	0.09	ENST00000295589.4	CCKAR Ensembl NCBI GeneCards UniProt Show fit	cholecystokinin A receptor
chr5_-_160685379 Show fit	0.09	ENST00000642502.1	ATP10B Ensembl NCBI GeneCards UniProt Show fit	ATPase phospholipid transporting 10B (putative)
chr7_+_141995872 Show fit	0.09	ENST00000497673.5 ENST00000620571.1 ENST00000475668.6	MGAM Ensembl NCBI GeneCards UniProt Show fit	maltase-glucoamylase
chr13_+_23570370 Show fit	0.09	ENST00000403372.6 ENST00000248484.9	TNFRSF19 Ensembl NCBI GeneCards UniProt Show fit	TNF receptor superfamily member 19
chr11_-_101129706 Show fit	0.09	ENST00000534013.5	PGR Ensembl NCBI GeneCards UniProt Show fit	progesterone receptor
chr4_-_48780242 Show fit	0.09	ENST00000507711.5 ENST00000358350.9	FRYL Ensembl NCBI GeneCards UniProt Show fit	FRY like transcription coactivator
chr10_-_93482194 Show fit	0.09	ENST00000358334.9 ENST00000371488.3	MYOF Ensembl NCBI GeneCards UniProt Show fit	myoferlin
chr7_-_88226987 Show fit	0.09	ENST00000394641.7	SRI Ensembl NCBI GeneCards UniProt Show fit	sorcin
chrX_-_1212634 Show fit	0.09	ENST00000381567.8 ENST00000381566.6 ENST00000400841.8	CRLF2 Ensembl NCBI GeneCards UniProt Show fit	cytokine receptor like factor 2
chr21_+_42653734 Show fit	0.09	ENST00000335512.8 ENST00000328862.10 ENST00000335440.10 ENST00000380328.6 ENST00000398225.7 ENST00000398227.7 ENST00000398229.7 ENST00000398232.7 ENST00000398234.7 ENST00000398236.7 ENST00000349112.7 ENST00000398224.3	PDE9A Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 9A
chr17_-_15566276 Show fit	0.09	ENST00000630868.1	CDRT1 Ensembl NCBI GeneCards UniProt Show fit	CMT1A duplicated region transcript 1
chr14_+_64914361 Show fit	0.08	ENST00000607599.6 ENST00000548752.7 ENST00000551947.6 ENST00000549115.7 ENST00000552002.7 ENST00000551093.6 ENST00000549987.1	CHURC1 Ensembl NCBI GeneCards UniProt Show fit CHURC1-FNTB Ensembl NCBI GeneCards UniProt Show fit	churchill domain containing 1 CHURC1-FNTB readthrough
chr15_+_78873723 Show fit	0.08	ENST00000559690.5 ENST00000559158.5	MORF4L1 Ensembl NCBI GeneCards UniProt Show fit	mortality factor 4 like 1
chr17_+_2033393 Show fit	0.08	ENST00000570477.6	DPH1 Ensembl NCBI GeneCards UniProt Show fit	diphthamide biosynthesis 1
chr12_-_10435940 Show fit	0.08	ENST00000381901.5 ENST00000381902.7 ENST00000539033.1	KLRC2 Ensembl NCBI GeneCards UniProt Show fit ENSG00000255641.1 Ensembl NCBI GeneCards UniProt Show fit	killer cell lectin like receptor C2 novel protein
chr11_-_129024157 Show fit	0.08	ENST00000392657.7	ARHGAP32 Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 32
chr7_+_75395629 Show fit	0.08	ENST00000323819.7 ENST00000430211.5	TRIM73 Ensembl NCBI GeneCards UniProt Show fit	tripartite motif containing 73
chr6_+_26199509 Show fit	0.08	ENST00000356530.5	H2BC7 Ensembl NCBI GeneCards UniProt Show fit	H2B clustered histone 7
chr4_-_68951763 Show fit	0.08	ENST00000251566.9	UGT2A3 Ensembl NCBI GeneCards UniProt Show fit	UDP glucuronosyltransferase family 2 member A3
chr11_+_105610012 Show fit	0.08	ENST00000393125.6	GRIA4 Ensembl NCBI GeneCards UniProt Show fit	glutamate ionotropic receptor AMPA type subunit 4
chr9_-_109119915 Show fit	0.08	ENST00000374586.8	TMEM245 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 245
chr4_-_99290975 Show fit	0.08	ENST00000209668.3	ADH1A Ensembl NCBI GeneCards UniProt Show fit	alcohol dehydrogenase 1A (class I), alpha polypeptide
chr6_+_33075952 Show fit	0.08	ENST00000418931.7	HLA-DPB1 Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class II, DP beta 1
chr1_+_54980610 Show fit	0.07	ENST00000371268.4	TMEM61 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 61
chr6_-_52087569 Show fit	0.07	ENST00000340994.4 ENST00000371117.8	PKHD1 Ensembl NCBI GeneCards UniProt Show fit	PKHD1 ciliary IPT domain containing fibrocystin/polyductin
chrX_-_154751017 Show fit	0.07	ENST00000369575.7 ENST00000369568.8 ENST00000424127.3	GAB3 Ensembl NCBI GeneCards UniProt Show fit	GRB2 associated binding protein 3
chr17_-_75667165 Show fit	0.07	ENST00000584999.1 ENST00000420326.6 ENST00000340830.9	RECQL5 Ensembl NCBI GeneCards UniProt Show fit	RecQ like helicase 5
chr6_+_112087576 Show fit	0.07	ENST00000368656.7 ENST00000604268.1	FAM229B Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 229 member B
chrX_-_18672101 Show fit	0.07	ENST00000379984.4	RS1 Ensembl NCBI GeneCards UniProt Show fit	retinoschisin 1
chr5_+_120531464 Show fit	0.07	ENST00000505123.5	PRR16 Ensembl NCBI GeneCards UniProt Show fit	proline rich 16
chr14_-_50397287 Show fit	0.07	ENST00000216378.2	CDKL1 Ensembl NCBI GeneCards UniProt Show fit	cyclin dependent kinase like 1
chr2_+_27032938 Show fit	0.07	ENST00000238788.14 ENST00000404032.7	TMEM214 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 214
chr19_-_52171600 Show fit	0.07	ENST00000682614.1	ZNF836 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 836
chr3_-_109118131 Show fit	0.07	ENST00000232603.10	MORC1 Ensembl NCBI GeneCards UniProt Show fit	MORC family CW-type zinc finger 1
chr19_-_52171443 Show fit	0.07	ENST00000598982.5 ENST00000594362.1 ENST00000597252.5	ENSG00000267827.5 Ensembl NCBI GeneCards UniProt Show fit ZNF836 Ensembl NCBI GeneCards UniProt Show fit	novel transcript zinc finger protein 836
chr14_+_30622304 Show fit	0.06	ENST00000676658.1 ENST00000679165.1 ENST00000676509.1 ENST00000678716.1 ENST00000678402.1 ENST00000678124.1 ENST00000677413.1 ENST00000553693.6 ENST00000469043.2 ENST00000676954.1 ENST00000676812.1 ENST00000678669.1 ENST00000676520.1 ENST00000557076.6 ENST00000544052.6 ENST00000458591.7 ENST00000677340.1 ENST00000676674.1 ENST00000396629.6 ENST00000678579.1	SCFD1 Ensembl NCBI GeneCards UniProt Show fit	sec1 family domain containing 1
chr3_-_46208304 Show fit	0.06	ENST00000296140.4	CCR1 Ensembl NCBI GeneCards UniProt Show fit	C-C motif chemokine receptor 1
chr1_-_247536440 Show fit	0.06	ENST00000366487.4 ENST00000641802.1	OR2C3 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 2 subfamily C member 3
chr5_+_170232912 Show fit	0.06	ENST00000524171.5 ENST00000517575.4 ENST00000518395.2 ENST00000593851.5	C5orf58 Ensembl NCBI GeneCards UniProt Show fit	chromosome 5 open reading frame 58
chr1_+_92168915 Show fit	0.06	ENST00000637221.2	BTBD8 Ensembl NCBI GeneCards UniProt Show fit	BTB domain containing 8
chrX_+_22136552 Show fit	0.06	ENST00000682888.1 ENST00000684356.1	PHEX Ensembl NCBI GeneCards UniProt Show fit	phosphate regulating endopeptidase homolog X-linked
chr6_-_134950081 Show fit	0.06	ENST00000367847.2 ENST00000265605.7 ENST00000367845.6	ALDH8A1 Ensembl NCBI GeneCards UniProt Show fit	aldehyde dehydrogenase 8 family member A1
chr10_-_93482326 Show fit	0.06	ENST00000359263.9	MYOF Ensembl NCBI GeneCards UniProt Show fit	myoferlin
chr3_+_111978996 Show fit	0.06	ENST00000273359.8 ENST00000494817.1	ABHD10 Ensembl NCBI GeneCards UniProt Show fit	abhydrolase domain containing 10, depalmitoylase
chr4_-_46124046 Show fit	0.06	ENST00000295452.5	GABRG1 Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid type A receptor subunit gamma1
chrX_+_135344784 Show fit	0.06	ENST00000370761.7 ENST00000339249.5	ZNF449 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 449
chr20_-_49188323 Show fit	0.06	ENST00000371856.7	STAU1 Ensembl NCBI GeneCards UniProt Show fit	staufen double-stranded RNA binding protein 1
chr19_+_17952236 Show fit	0.06	ENST00000682733.1	KCNN1 Ensembl NCBI GeneCards UniProt Show fit	potassium calcium-activated channel subfamily N member 1
chr1_-_217631034 Show fit	0.06	ENST00000366934.3 ENST00000366935.8	GPATCH2 Ensembl NCBI GeneCards UniProt Show fit	G-patch domain containing 2
chr6_-_73225465 Show fit	0.06	ENST00000370388.4	KHDC1L Ensembl NCBI GeneCards UniProt Show fit	KH domain containing 1 like
chr12_-_10388976 Show fit	0.05	ENST00000540818.5	KLRK1 Ensembl NCBI GeneCards UniProt Show fit	killer cell lectin like receptor K1
chr6_-_30161200 Show fit	0.05	ENST00000449742.7	TRIM10 Ensembl NCBI GeneCards UniProt Show fit	tripartite motif containing 10
chr1_-_202889099 Show fit	0.05	ENST00000367262.4	RABIF Ensembl NCBI GeneCards UniProt Show fit	RAB interacting factor
chr2_+_227472132 Show fit	0.05	ENST00000409979.6 ENST00000310078.13	AGFG1 Ensembl NCBI GeneCards UniProt Show fit	ArfGAP with FG repeats 1
chr4_+_89901979 Show fit	0.05	ENST00000508372.1	MMRN1 Ensembl NCBI GeneCards UniProt Show fit	multimerin 1
chr20_-_49188360 Show fit	0.05	ENST00000371828.7 ENST00000340954.11 ENST00000347458.9 ENST00000360426.8 ENST00000371792.5 ENST00000371802.5 ENST00000437404.2	STAU1 Ensembl NCBI GeneCards UniProt Show fit	staufen double-stranded RNA binding protein 1
chr3_+_57060658 Show fit	0.05	ENST00000334325.2	SPATA12 Ensembl NCBI GeneCards UniProt Show fit	spermatogenesis associated 12
chr11_-_31804067 Show fit	0.05	ENST00000639548.1 ENST00000640125.1 ENST00000481563.6 ENST00000639079.1 ENST00000638762.1 ENST00000638346.1	PAX6 Ensembl NCBI GeneCards UniProt Show fit	paired box 6
chr10_-_100185993 Show fit	0.05	ENST00000421367.7 ENST00000370408.2 ENST00000407654.7	ERLIN1 Ensembl NCBI GeneCards UniProt Show fit	ER lipid raft associated 1
chr22_+_39399715 Show fit	0.05	ENST00000216160.11 ENST00000331454.3	TAB1 Ensembl NCBI GeneCards UniProt Show fit	TGF-beta activated kinase 1 (MAP3K7) binding protein 1
chr12_+_56080155 Show fit	0.05	ENST00000267101.8	ERBB3 Ensembl NCBI GeneCards UniProt Show fit	erb-b2 receptor tyrosine kinase 3
chr15_-_55408245 Show fit	0.05	ENST00000563171.5 ENST00000425574.7 ENST00000442196.8 ENST00000564092.1	CCPG1 Ensembl NCBI GeneCards UniProt Show fit	cell cycle progression 1
chr13_+_50015438 Show fit	0.04	ENST00000312942.2	KCNRG Ensembl NCBI GeneCards UniProt Show fit	potassium channel regulator
chr17_-_31314040 Show fit	0.04	ENST00000330927.5	EVI2B Ensembl NCBI GeneCards UniProt Show fit	ecotropic viral integration site 2B
chr12_+_10010627 Show fit	0.04	ENST00000338896.11 ENST00000396502.5	CLEC12B Ensembl NCBI GeneCards UniProt Show fit	C-type lectin domain family 12 member B
chr10_-_24706622 Show fit	0.04	ENST00000680286.1	ARHGAP21 Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 21
chr4_+_75724569 Show fit	0.04	ENST00000514213.7 ENST00000264904.8	USO1 Ensembl NCBI GeneCards UniProt Show fit	USO1 vesicle transport factor
chr17_+_56153458 Show fit	0.04	ENST00000318698.6 ENST00000682825.1 ENST00000566473.6	ANKFN1 Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat and fibronectin type III domain containing 1
chr6_+_113857333 Show fit	0.03	ENST00000612661.2	MARCKS Ensembl NCBI GeneCards UniProt Show fit	myristoylated alanine rich protein kinase C substrate
chr19_+_40775511 Show fit	0.03	ENST00000263369.4 ENST00000597140.5	MIA Ensembl NCBI GeneCards UniProt Show fit	MIA SH3 domain containing
chr6_+_10887036 Show fit	0.03	ENST00000283141.11	SYCP2L Ensembl NCBI GeneCards UniProt Show fit	synaptonemal complex protein 2 like
chr13_+_48976597 Show fit	0.03	ENST00000541916.5	FNDC3A Ensembl NCBI GeneCards UniProt Show fit	fibronectin type III domain containing 3A
chr1_-_66801276 Show fit	0.03	ENST00000304526.3	INSL5 Ensembl NCBI GeneCards UniProt Show fit	insulin like 5
chr10_+_79841358 Show fit	0.03	ENST00000602967.5	NUTM2E Ensembl NCBI GeneCards UniProt Show fit	NUT family member 2E
chr3_+_16174628 Show fit	0.03	ENST00000339732.10	GALNT15 Ensembl NCBI GeneCards UniProt Show fit	polypeptide N-acetylgalactosaminyltransferase 15
chr3_+_102099244 Show fit	0.03	ENST00000491959.5	ZPLD1 Ensembl NCBI GeneCards UniProt Show fit	zona pellucida like domain containing 1
chr11_-_64917200 Show fit	0.03	ENST00000377264.8 ENST00000421419.3	ATG2A Ensembl NCBI GeneCards UniProt Show fit	autophagy related 2A
chr5_-_143434677 Show fit	0.02	ENST00000504572.5	NR3C1 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 3 group C member 1
chr9_+_129081098 Show fit	0.02	ENST00000406974.7 ENST00000372546.9	DOLPP1 Ensembl NCBI GeneCards UniProt Show fit	dolichyldiphosphatase 1
chr2_-_150487658 Show fit	0.02	ENST00000375734.6 ENST00000263895.9 ENST00000454202.5	RND3 Ensembl NCBI GeneCards UniProt Show fit	Rho family GTPase 3
chr15_-_55408467 Show fit	0.02	ENST00000310958.10	CCPG1 Ensembl NCBI GeneCards UniProt Show fit	cell cycle progression 1
chrX_-_32412220 Show fit	0.02	ENST00000619831.5	DMD Ensembl NCBI GeneCards UniProt Show fit	dystrophin
chr12_-_13095664 Show fit	0.02	ENST00000337630.10 ENST00000545699.1	GSG1 Ensembl NCBI GeneCards UniProt Show fit	germ cell associated 1
chr17_-_64390852 Show fit	0.02	ENST00000563924.6	PECAM1 Ensembl NCBI GeneCards UniProt Show fit	platelet and endothelial cell adhesion molecule 1
chr8_-_33567118 Show fit	0.02	ENST00000256257.2	RNF122 Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 122
chr5_-_115625972 Show fit	0.02	ENST00000333314.3 ENST00000456936.4	TMED7-TICAM2 Ensembl NCBI GeneCards UniProt Show fit TMED7 Ensembl NCBI GeneCards UniProt Show fit	TMED7-TICAM2 readthrough transmembrane p24 trafficking protein 7
chr11_-_105023136 Show fit	0.02	ENST00000526056.5 ENST00000531367.5 ENST00000456094.1 ENST00000444749.6 ENST00000393141.6 ENST00000418434.5 ENST00000260315.8	CASP5 Ensembl NCBI GeneCards UniProt Show fit	caspase 5
chr9_+_127264740 Show fit	0.02	ENST00000373387.9	GARNL3 Ensembl NCBI GeneCards UniProt Show fit	GTPase activating Rap/RanGAP domain like 3
chr1_-_157552455 Show fit	0.02	ENST00000368190.7 ENST00000368189.3	FCRL5 Ensembl NCBI GeneCards UniProt Show fit	Fc receptor like 5
chr12_-_15221394 Show fit	0.02	ENST00000537647.5 ENST00000256953.6 ENST00000546331.5	RERG Ensembl NCBI GeneCards UniProt Show fit	RAS like estrogen regulated growth inhibitor
chr6_-_2750912 Show fit	0.02	ENST00000274643.9	MYLK4 Ensembl NCBI GeneCards UniProt Show fit	myosin light chain kinase family member 4
chr1_+_192575765 Show fit	0.02	ENST00000469578.2 ENST00000367459.8	RGS1 Ensembl NCBI GeneCards UniProt Show fit	regulator of G protein signaling 1
chr13_+_21140774 Show fit	0.02	ENST00000450573.5 ENST00000467636.1	SAP18 Ensembl NCBI GeneCards UniProt Show fit	Sin3A associated protein 18
chr8_-_38150943 Show fit	0.02	ENST00000276449.9	STAR Ensembl NCBI GeneCards UniProt Show fit	steroidogenic acute regulatory protein
chr20_-_31390483 Show fit	0.02	ENST00000376315.2	DEFB119 Ensembl NCBI GeneCards UniProt Show fit	defensin beta 119
chr1_-_11805294 Show fit	0.02	ENST00000413656.5 ENST00000376592.6 ENST00000376585.6	MTHFR Ensembl NCBI GeneCards UniProt Show fit	methylenetetrahydrofolate reductase
chr14_+_32329341 Show fit	0.02	ENST00000557354.5 ENST00000557102.1 ENST00000557272.1	AKAP6 Ensembl NCBI GeneCards UniProt Show fit	A-kinase anchoring protein 6
chr1_+_74733144 Show fit	0.02	ENST00000457880.6 ENST00000370867.8	TYW3 Ensembl NCBI GeneCards UniProt Show fit	tRNA-yW synthesizing protein 3 homolog

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0070408	carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.1	0.3	GO:0061182	negative regulation of chondrocyte development(GO:0061182)
0.1	0.2	GO:0006566	threonine metabolic process(GO:0006566)
0.1	0.2	GO:1902269	putrescine transport(GO:0015847) positive regulation of polyamine transmembrane transport(GO:1902269)
0.1	0.2	GO:0072709	cellular response to sorbitol(GO:0072709)
0.0	0.4	GO:0048014	Tie signaling pathway(GO:0048014)
0.0	0.2	GO:0000023	maltose metabolic process(GO:0000023)
0.0	0.5	GO:0071492	cellular response to UV-A(GO:0071492)
0.0	0.2	GO:1990414	replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0	0.2	GO:0072660	maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0	0.2	GO:0071395	response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0	0.2	GO:0046086	AMP catabolic process(GO:0006196) adenosine biosynthetic process(GO:0046086)
0.0	0.3	GO:0070131	positive regulation of mitochondrial translation(GO:0070131)
0.0	0.1	GO:0098923	retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
0.0	0.1	GO:2000342	negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0	0.3	GO:1904352	positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0	0.4	GO:0033617	mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.0	0.2	GO:0097577	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0	0.2	GO:0060754	positive regulation of mast cell chemotaxis(GO:0060754)
0.0	0.4	GO:0052695	cellular glucuronidation(GO:0052695)
0.0	0.1	GO:0006982	response to lipid hydroperoxide(GO:0006982)
0.0	0.1	GO:2000502	negative regulation of natural killer cell chemotaxis(GO:2000502)
0.0	0.1	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0	0.4	GO:0006704	glucocorticoid biosynthetic process(GO:0006704)
0.0	0.2	GO:0008343	adult feeding behavior(GO:0008343)
0.0	0.2	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	0.1	GO:1904383	response to sodium phosphate(GO:1904383)
0.0	0.3	GO:0042753	positive regulation of circadian rhythm(GO:0042753)
0.0	0.1	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.0	GO:0002769	natural killer cell inhibitory signaling pathway(GO:0002769)
0.0	0.1	GO:0046726	positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0	0.1	GO:0044026	DNA hypermethylation(GO:0044026)

Gene overrepresentation in cellular component category:

Total log-likelihood	Term	Description
0.7	GO:0042613	MHC class II protein complex(GO:0042613)
0.2	GO:0044326	dendritic spine neck(GO:0044326)
0.1	GO:0005965	protein farnesyltransferase complex(GO:0005965)
0.1	GO:0033503	HULC complex(GO:0033503)
0.0	GO:0001674	female germ cell nucleus(GO:0001674)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	GO:0004087	carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.1	0.4	GO:0003845	11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1	0.4	GO:0004967	glucagon receptor activity(GO:0004967)
0.1	0.2	GO:0004339	glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.1	0.2	GO:0015203	polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
0.0	0.3	GO:0008142	oxysterol binding(GO:0008142)
0.0	0.6	GO:0032395	MHC class II receptor activity(GO:0032395)
0.0	0.2	GO:0043183	vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0	0.2	GO:0030060	L-malate dehydrogenase activity(GO:0030060)
0.0	0.1	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.2	GO:0047086	phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.0	0.1	GO:0032093	SAM domain binding(GO:0032093)
0.0	0.2	GO:0009378	four-way junction helicase activity(GO:0009378)
0.0	0.2	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.2	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.0	0.1	GO:0004660	protein farnesyltransferase activity(GO:0004660)
0.0	0.1	GO:0023024	MHC class I protein complex binding(GO:0023024)
0.0	0.3	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.3	GO:0031005	filamin binding(GO:0031005)
0.0	0.2	GO:0004062	aryl sulfotransferase activity(GO:0004062)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.2	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.2	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.3	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.2	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.4	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.2	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.4	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.3	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.2	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions

Results for HMX2

Z-value: 0.49

Motif logo

Transcription factors associated with HMX2

Activity-expression correlation:

Activity profile of HMX2 motif

Sorted Z-values of HMX2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HMX2

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: