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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for HNF1A_HNF1B

Z-value: 0.94

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Transcription factors associated with HNF1A_HNF1B

Gene Symbol Gene ID Gene Info
HNF1A
ENSG00000135100.19 HNF1A
HNF1B
ENSG00000275410.6 HNF1B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HNF1Ahg38_v1_chr12_+_120978537_120978568-0.451.2e-02Click!
HNF1Bhg38_v1_chr17_-_37745018_377450690.163.9e-01Click!

Activity profile of HNF1A_HNF1B motif

Sorted Z-values of HNF1A_HNF1B motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HNF1A_HNF1B

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr19_+_735026 7.37 ENST00000592155.5
ENST00000590161.2
PALM
paralemmin
chrX_-_15600953 3.31 ENST00000679212.1
ENST00000679278.1
ENST00000678046.1
ENST00000252519.8
ACE2
angiotensin I converting enzyme 2
chr4_-_109801978 2.60 ENST00000510800.1
ENST00000512148.5
ENST00000394634.7
ENST00000394635.8
ENST00000645635.1
CFI
ENSG00000285330.1
complement factor I
novel protein
chr1_+_103750406 2.30 ENST00000370079.3
AMY1C
amylase alpha 1C
chr1_+_103617427 2.29 ENST00000423678.2
ENST00000414303.7
AMY2A
amylase alpha 2A
chr19_+_49513353 2.28 ENST00000596975.5
FCGRT
Fc fragment of IgG receptor and transporter
chr1_+_18480930 2.26 ENST00000400664.3
KLHDC7A
kelch domain containing 7A
chr7_+_141995826 2.16 ENST00000549489.6
MGAM
maltase-glucoamylase
chr7_+_141995872 2.16 ENST00000497673.5
ENST00000620571.1
ENST00000475668.6
MGAM
maltase-glucoamylase
chr17_+_4788926 1.94 ENST00000331264.8
GLTPD2
glycolipid transfer protein domain containing 2
chr17_+_28473635 1.88 ENST00000314669.10
ENST00000545060.2
SLC13A2
solute carrier family 13 member 2
chrX_-_15601077 1.85 ENST00000680121.1
ACE2
angiotensin I converting enzyme 2
chr18_+_58341038 1.83 ENST00000679791.1
NEDD4L
NEDD4 like E3 ubiquitin protein ligase
chr17_+_28473278 1.73 ENST00000444914.7
SLC13A2
solute carrier family 13 member 2
chr4_-_99352730 1.67 ENST00000510055.5
ENST00000515683.6
ENST00000511397.3
ADH1C
alcohol dehydrogenase 1C (class I), gamma polypeptide
chr16_+_20764036 1.64 ENST00000440284.6
ACSM3
acyl-CoA synthetase medium chain family member 3
chr19_+_49513154 1.62 ENST00000426395.7
ENST00000600273.5
ENST00000599988.5
FCGRT
Fc fragment of IgG receptor and transporter
chr22_+_30607145 1.55 ENST00000405742.7
TCN2
transcobalamin 2
chr1_+_162381703 1.54 ENST00000458626.4
C1orf226
chromosome 1 open reading frame 226
chr22_+_30607167 1.50 ENST00000215838.8
TCN2
transcobalamin 2
chr22_+_30607072 1.50 ENST00000450638.5
TCN2
transcobalamin 2
chr8_-_94208548 1.41 ENST00000027335.8
ENST00000441892.6
ENST00000521491.1
CDH17
cadherin 17
chr12_+_109347903 1.36 ENST00000310903.9
MYO1H
myosin IH
chr7_-_50565381 1.23 ENST00000444124.7
DDC
dopa decarboxylase
chr14_-_94388589 1.23 ENST00000402629.1
ENST00000556091.1
ENST00000393087.9
ENST00000554720.1
SERPINA1
serpin family A member 1
chr6_-_29045175 1.20 ENST00000377175.2
OR2W1
olfactory receptor family 2 subfamily W member 1
chr17_-_352784 1.17 ENST00000577079.5
ENST00000331302.12
ENST00000618002.4
ENST00000536489.6
RPH3AL
rabphilin 3A like (without C2 domains)
chr5_-_35195236 1.13 ENST00000509839.5
PRLR
prolactin receptor
chr17_+_70075215 1.11 ENST00000283936.5
ENST00000615244.4
ENST00000392671.6
KCNJ16
potassium inwardly rectifying channel subfamily J member 16
chr17_+_70075317 1.11 ENST00000589377.1
KCNJ16
potassium inwardly rectifying channel subfamily J member 16
chr6_-_154430495 1.03 ENST00000424998.3
CNKSR3
CNKSR family member 3
chr22_-_32255344 0.98 ENST00000266086.6
SLC5A4
solute carrier family 5 member 4
chrX_-_106038721 0.95 ENST00000372563.2
SERPINA7
serpin family A member 7
chr3_-_138115594 0.89 ENST00000327532.7
ENST00000467030.5
DZIP1L
DAZ interacting zinc finger protein 1 like
chr3_-_157503574 0.88 ENST00000494677.5
ENST00000468233.5
VEPH1
ventricular zone expressed PH domain containing 1
chr13_-_103066411 0.85 ENST00000245312.5
SLC10A2
solute carrier family 10 member 2
chr16_+_21233672 0.85 ENST00000311620.7
ANKS4B
ankyrin repeat and sterile alpha motif domain containing 4B
chr9_-_121050264 0.82 ENST00000223642.3
C5
complement C5
chr17_-_28406160 0.79 ENST00000618626.1
ENST00000612814.5
SLC46A1
solute carrier family 46 member 1
chr2_-_96505345 0.77 ENST00000310865.7
ENST00000451794.6
NEURL3
neuralized E3 ubiquitin protein ligase 3
chr4_-_1173168 0.71 ENST00000514490.5
ENST00000431380.5
ENST00000503765.5
SPON2
spondin 2
chr13_+_95433593 0.70 ENST00000376873.7
CLDN10
claudin 10
chr3_-_74521140 0.68 ENST00000263665.6
CNTN3
contactin 3
chr2_+_37950432 0.64 ENST00000407257.5
ENST00000417700.6
ENST00000234195.7
ENST00000442857.5
RMDN2
regulator of microtubule dynamics 2
chr5_+_141192330 0.63 ENST00000239446.6
PCDHB10
protocadherin beta 10
chr16_-_55875299 0.63 ENST00000520435.2
CES5A
carboxylesterase 5A
chr6_-_52763473 0.62 ENST00000493422.3
GSTA2
glutathione S-transferase alpha 2
chr6_-_25930611 0.62 ENST00000360488.7
SLC17A2
solute carrier family 17 member 2
chr12_-_39443390 0.62 ENST00000361961.7
KIF21A
kinesin family member 21A
chr4_-_69653223 0.62 ENST00000286604.8
ENST00000505512.1
ENST00000514019.1
UGT2A1
UDP glucuronosyltransferase family 2 member A1 complex locus
chr6_-_25930678 0.62 ENST00000377850.8
SLC17A2
solute carrier family 17 member 2
chr14_+_20688756 0.59 ENST00000397990.5
ENST00000555597.1
ANG
RNASE4
angiogenin
ribonuclease A family member 4
chr16_-_55875358 0.59 ENST00000319165.13
ENST00000290567.14
CES5A
carboxylesterase 5A
chr4_-_99290975 0.59 ENST00000209668.3
ADH1A
alcohol dehydrogenase 1A (class I), alpha polypeptide
chr2_+_132416795 0.57 ENST00000329321.4
GPR39
G protein-coupled receptor 39
chr12_+_20810698 0.55 ENST00000540853.5
ENST00000381545.8
SLCO1B3
solute carrier organic anion transporter family member 1B3
chr8_-_69833338 0.54 ENST00000524945.5
SLCO5A1
solute carrier organic anion transporter family member 5A1
chr12_-_91180365 0.52 ENST00000547937.5
DCN
decorin
chr8_+_22053543 0.51 ENST00000519850.5
ENST00000381470.7
DMTN
dematin actin binding protein
chr2_-_227379297 0.51 ENST00000304568.4
TM4SF20
transmembrane 4 L six family member 20
chr22_-_30574572 0.51 ENST00000402369.5
GAL3ST1
galactose-3-O-sulfotransferase 1
chr6_+_125749623 0.51 ENST00000368364.4
HEY2
hes related family bHLH transcription factor with YRPW motif 2
chr4_+_3441960 0.48 ENST00000382774.8
ENST00000511533.1
HGFAC
HGF activator
chr8_+_103880412 0.46 ENST00000436393.6
RIMS2
regulating synaptic membrane exocytosis 2
chrX_+_134237047 0.44 ENST00000370809.4
ENST00000517294.5
CCDC160
coiled-coil domain containing 160
chr8_-_107498041 0.44 ENST00000297450.7
ANGPT1
angiopoietin 1
chr8_-_107497909 0.43 ENST00000517746.6
ANGPT1
angiopoietin 1
chr6_+_137871208 0.43 ENST00000614035.4
ENST00000621150.3
ENST00000619035.4
ENST00000615468.4
ENST00000620204.3
TNFAIP3
TNF alpha induced protein 3
chr5_+_132369691 0.43 ENST00000245407.8
SLC22A5
solute carrier family 22 member 5
chr9_+_128098304 0.41 ENST00000373064.9
SLC25A25
solute carrier family 25 member 25
chr6_+_47656436 0.39 ENST00000507065.5
ENST00000296862.5
ADGRF2
adhesion G protein-coupled receptor F2
chr5_+_68290637 0.38 ENST00000336483.9
PIK3R1
phosphoinositide-3-kinase regulatory subunit 1
chr6_+_54307856 0.37 ENST00000370869.7
TINAG
tubulointerstitial nephritis antigen
chr16_-_69351778 0.37 ENST00000288025.4
TMED6
transmembrane p24 trafficking protein 6
chr6_-_52087569 0.36 ENST00000340994.4
ENST00000371117.8
PKHD1
PKHD1 ciliary IPT domain containing fibrocystin/polyductin
chr9_+_79571767 0.34 ENST00000376544.7
TLE4
TLE family member 4, transcriptional corepressor
chr9_+_79571956 0.34 ENST00000376552.8
TLE4
TLE family member 4, transcriptional corepressor
chr20_+_44401397 0.33 ENST00000682427.1
ENST00000681977.1
ENST00000684136.1
ENST00000684046.1
ENST00000684476.1
ENST00000619550.5
ENST00000682169.1
HNF4A
hepatocyte nuclear factor 4 alpha
chr11_-_65381951 0.33 ENST00000526432.5
ENST00000527174.5
SLC25A45
solute carrier family 25 member 45
chr11_+_118533032 0.32 ENST00000526853.1
TMEM25
transmembrane protein 25
chr3_-_49429252 0.32 ENST00000615713.4
NICN1
nicolin 1
chr2_+_87748087 0.32 ENST00000359481.9
PLGLB2
plasminogen like B2
chr11_+_2384603 0.32 ENST00000527343.5
ENST00000464784.6
CD81
CD81 molecule
chr10_+_84173793 0.30 ENST00000372126.4
C10orf99
chromosome 10 open reading frame 99
chr2_-_88128049 0.30 ENST00000393750.3
ENST00000295834.8
FABP1
fatty acid binding protein 1
chr6_+_131250375 0.30 ENST00000474850.2
AKAP7
A-kinase anchoring protein 7
chr19_+_11239602 0.29 ENST00000252453.12
ANGPTL8
angiopoietin like 8
chr8_-_17895487 0.29 ENST00000427924.5
ENST00000381841.4
FGL1
fibrinogen like 1
chr3_-_161372821 0.28 ENST00000617024.1
ENST00000359175.8
SPTSSB
serine palmitoyltransferase small subunit B
chr11_-_117824734 0.27 ENST00000292079.7
FXYD2
FXYD domain containing ion transport regulator 2
chr12_+_25052732 0.27 ENST00000547044.5
IRAG2
inositol 1,4,5-triphosphate receptor associated 2
chr11_+_560956 0.26 ENST00000397582.7
ENST00000397583.8
RASSF7
Ras association domain family member 7
chr17_+_1742836 0.25 ENST00000324015.7
ENST00000450523.6
ENST00000453723.5
ENST00000453066.6
ENST00000382061.5
SERPINF2
serpin family F member 2
chr20_+_44401222 0.25 ENST00000316099.9
HNF4A
hepatocyte nuclear factor 4 alpha
chr12_-_8540873 0.25 ENST00000545274.5
ENST00000446457.6
ENST00000299663.8
CLEC4E
C-type lectin domain family 4 member E
chr17_+_37375974 0.25 ENST00000615133.2
ENST00000611038.4
C17orf78
chromosome 17 open reading frame 78
chr1_+_207104226 0.25 ENST00000367070.8
C4BPA
complement component 4 binding protein alpha
chr3_-_165078480 0.25 ENST00000264382.8
SI
sucrase-isomaltase
chr2_+_233617626 0.24 ENST00000373450.5
UGT1A8
UDP glucuronosyltransferase family 1 member A8
chr4_+_119135825 0.24 ENST00000307128.6
MYOZ2
myozenin 2
chr12_+_100503352 0.24 ENST00000551379.5
ENST00000188403.7
NR1H4
nuclear receptor subfamily 1 group H member 4
chr6_+_54308429 0.23 ENST00000259782.9
ENST00000370864.3
TINAG
tubulointerstitial nephritis antigen
chr12_+_100473708 0.23 ENST00000548884.5
ENST00000392986.8
NR1H4
nuclear receptor subfamily 1 group H member 4
chr6_-_160664270 0.22 ENST00000316300.10
LPA
lipoprotein(a)
chr1_+_119368773 0.22 ENST00000457318.5
ENST00000622548.4
ENST00000325945.4
HAO2
hydroxyacid oxidase 2
chr12_+_100473951 0.22 ENST00000648861.1
ENST00000546380.1
NR1H4
nuclear receptor subfamily 1 group H member 4
chr4_+_99574812 0.21 ENST00000422897.6
ENST00000265517.10
MTTP
microsomal triglyceride transfer protein
chr11_+_46719193 0.21 ENST00000311907.10
ENST00000530231.5
ENST00000442468.1
F2
coagulation factor II, thrombin
chr19_+_1205761 0.21 ENST00000326873.12
ENST00000586243.5
STK11
serine/threonine kinase 11
chr11_-_129024157 0.21 ENST00000392657.7
ARHGAP32
Rho GTPase activating protein 32
chr20_-_7940444 0.21 ENST00000378789.4
HAO1
hydroxyacid oxidase 1
chr8_-_86743626 0.20 ENST00000320005.6
CNGB3
cyclic nucleotide gated channel subunit beta 3
chr10_-_32378720 0.20 ENST00000375110.6
EPC1
enhancer of polycomb homolog 1
chr14_+_39233908 0.20 ENST00000280082.4
MIA2
MIA SH3 domain ER export factor 2
chr16_-_57797764 0.20 ENST00000465878.6
ENST00000561524.5
KIFC3
kinesin family member C3
chr6_-_116060859 0.19 ENST00000606080.2
FRK
fyn related Src family tyrosine kinase
chr7_-_155809072 0.19 ENST00000430104.5
SHH
sonic hedgehog signaling molecule
chr1_-_42164737 0.19 ENST00000357001.3
GUCA2A
guanylate cyclase activator 2A
chr3_+_186666003 0.18 ENST00000232003.5
HRG
histidine rich glycoprotein
chr10_-_126670686 0.18 ENST00000488181.3
C10orf90
chromosome 10 open reading frame 90
chr16_+_14708944 0.18 ENST00000526520.5
ENST00000531598.6
NPIPA3
nuclear pore complex interacting protein family member A3
chr15_+_86079863 0.18 ENST00000614907.3
ENST00000441037.7
AGBL1
ATP/GTP binding protein like 1
chr2_-_162074182 0.18 ENST00000360534.8
DPP4
dipeptidyl peptidase 4
chr10_+_110005804 0.17 ENST00000360162.7
ADD3
adducin 3
chr7_+_152759744 0.17 ENST00000377776.7
ENST00000256001.13
ENST00000397282.2
ACTR3B
actin related protein 3B
chr13_+_33016415 0.17 ENST00000380099.4
KL
klotho
chr2_-_162074394 0.17 ENST00000676810.1
DPP4
dipeptidyl peptidase 4
chr1_-_197067234 0.17 ENST00000367412.2
F13B
coagulation factor XIII B chain
chr19_-_49061997 0.17 ENST00000593537.1
NTF4
neurotrophin 4
chr1_+_84301694 0.17 ENST00000394834.8
ENST00000370669.5
SAMD13
sterile alpha motif domain containing 13
chr8_-_86230360 0.16 ENST00000419776.2
ENST00000297524.8
SLC7A13
solute carrier family 7 member 13
chr3_+_184230373 0.15 ENST00000426955.6
VWA5B2
von Willebrand factor A domain containing 5B2
chr9_+_137230757 0.15 ENST00000673865.1
ENST00000538474.5
ENST00000673835.1
ENST00000673953.1
ENST00000361134.2
SLC34A3
solute carrier family 34 member 3
chr22_+_32043253 0.15 ENST00000266088.9
SLC5A1
solute carrier family 5 member 1
chr6_-_25874212 0.15 ENST00000361703.10
ENST00000397060.8
SLC17A3
solute carrier family 17 member 3
chr7_-_128910676 0.14 ENST00000620378.1
ENST00000610776.4
ENST00000613019.4
KCP
kielin cysteine rich BMP regulator
chr3_-_142963663 0.14 ENST00000340634.6
PAQR9
progestin and adipoQ receptor family member 9
chr2_+_233760265 0.14 ENST00000305208.10
ENST00000360418.4
UGT1A1
UDP glucuronosyltransferase family 1 member A1
chr2_-_157444044 0.14 ENST00000264192.8
CYTIP
cytohesin 1 interacting protein
chr5_+_73813518 0.13 ENST00000296799.8
ARHGEF28
Rho guanine nucleotide exchange factor 28
chr12_+_69739370 0.12 ENST00000550536.5
ENST00000362025.9
RAB3IP
RAB3A interacting protein
chr16_-_20576277 0.12 ENST00000566384.5
ENST00000565232.5
ENST00000567001.5
ENST00000565322.5
ENST00000569344.5
ENST00000329697.10
ENST00000568882.1
ACSM2B
acyl-CoA synthetase medium chain family member 2B
chr14_+_24120956 0.12 ENST00000558325.2
ENSG00000259371.2
novel protein
chr10_-_70888546 0.12 ENST00000299299.4
PCBD1
pterin-4 alpha-carbinolamine dehydratase 1
chr3_-_138174879 0.12 ENST00000260803.9
DBR1
debranching RNA lariats 1
chr13_-_41019289 0.11 ENST00000239882.7
ELF1
E74 like ETS transcription factor 1
chr17_+_7407838 0.10 ENST00000302926.7
NLGN2
neuroligin 2
chr5_-_139383284 0.10 ENST00000353963.7
ENST00000348729.8
SLC23A1
solute carrier family 23 member 1
chr14_-_57493827 0.10 ENST00000526336.1
ENST00000216445.8
CCDC198
coiled-coil domain containing 198
chr7_-_88226987 0.10 ENST00000394641.7
SRI
sorcin
chr17_+_50746534 0.10 ENST00000511974.5
LUC7L3
LUC7 like 3 pre-mRNA splicing factor
chr11_+_20599602 0.10 ENST00000525748.6
SLC6A5
solute carrier family 6 member 5
chr16_+_20451596 0.10 ENST00000575690.5
ENST00000571894.1
ACSM2A
acyl-CoA synthetase medium chain family member 2A
chr7_-_88226965 0.10 ENST00000490437.5
ENST00000431660.5
SRI
sorcin
chr15_-_55408018 0.10 ENST00000569205.5
CCPG1
cell cycle progression 1
chr20_+_44401269 0.09 ENST00000443598.6
ENST00000415691.2
HNF4A
hepatocyte nuclear factor 4 alpha
chr10_-_37857582 0.09 ENST00000395867.8
ENST00000611278.4
ZNF248
zinc finger protein 248
chr16_+_20451563 0.09 ENST00000417235.6
ENST00000219054.10
ACSM2A
acyl-CoA synthetase medium chain family member 2A
chr22_-_38110675 0.09 ENST00000381669.8
BAIAP2L2
BAR/IMD domain containing adaptor protein 2 like 2
chr16_+_81238682 0.08 ENST00000258168.7
ENST00000564552.1
BCO1
beta-carotene oxygenase 1
chr3_+_180602156 0.08 ENST00000296015.9
ENST00000491380.5
ENST00000412756.6
ENST00000382584.8
TTC14
tetratricopeptide repeat domain 14
chr13_+_27251569 0.08 ENST00000272274.8
ENST00000319826.8
ENST00000326092.8
RPL21
ribosomal protein L21
chr7_+_33904911 0.08 ENST00000297161.6
BMPER
BMP binding endothelial regulator
chr11_+_64591214 0.08 ENST00000377574.6
ENST00000473690.5
SLC22A12
solute carrier family 22 member 12
chr11_-_83682414 0.08 ENST00000404783.7
DLG2
discs large MAGUK scaffold protein 2
chr5_+_141392616 0.07 ENST00000398604.3
PCDHGA8
protocadherin gamma subfamily A, 8
chr12_+_100473916 0.07 ENST00000549996.5
NR1H4
nuclear receptor subfamily 1 group H member 4
chr3_+_66220984 0.07 ENST00000354883.11
ENST00000336733.10
SLC25A26
solute carrier family 25 member 26
chr12_-_23949642 0.07 ENST00000537393.5
ENST00000451604.7
ENST00000381381.6
SOX5
SRY-box transcription factor 5
chr2_+_233729042 0.07 ENST00000482026.6
UGT1A3
UDP glucuronosyltransferase family 1 member A3
chr19_-_41627051 0.07 ENST00000221954.6
ENST00000600925.1
CEACAM4
CEA cell adhesion molecule 4
chr7_-_44541262 0.06 ENST00000289547.8
ENST00000546276.5
ENST00000423141.1
NPC1L1
NPC1 like intracellular cholesterol transporter 1
chr9_-_91950201 0.06 ENST00000375708.4
ROR2
receptor tyrosine kinase like orphan receptor 2
chr7_-_122304738 0.06 ENST00000442488.7
FEZF1
FEZ family zinc finger 1
chr4_+_73404255 0.06 ENST00000621628.4
ENST00000621085.4
ENST00000415165.6
ENST00000295897.9
ENST00000503124.5
ENST00000509063.5
ENST00000401494.7
ALB
albumin
chr12_-_76486061 0.05 ENST00000548341.5
OSBPL8
oxysterol binding protein like 8
chr19_-_11529094 0.05 ENST00000588998.5
ENST00000586149.1
ECSIT
ECSIT signaling integrator
chr6_+_160702238 0.05 ENST00000366924.6
ENST00000308192.14
ENST00000418964.1
PLG
plasminogen
chr10_-_50885656 0.05 ENST00000374001.6
ENST00000395489.6
ENST00000282641.6
ENST00000395495.5
ENST00000373995.7
ENST00000414883.1
A1CF
APOBEC1 complementation factor
chr19_-_11529116 0.05 ENST00000592312.5
ENST00000590480.1
ENST00000585318.5
ENST00000270517.12
ENST00000252440.11
ENST00000417981.6
ECSIT
ECSIT signaling integrator
chr6_+_167122742 0.05 ENST00000341935.9
ENST00000349984.6
CCR6
C-C motif chemokine receptor 6
chr17_+_50746614 0.05 ENST00000513969.5
ENST00000503728.1
LUC7L3
LUC7 like 3 pre-mRNA splicing factor
chr3_+_107599309 0.04 ENST00000406780.5
BBX
BBX high mobility group box domain containing
chr1_+_207089283 0.04 ENST00000391923.1
C4BPB
complement component 4 binding protein beta
chr1_+_207089233 0.03 ENST00000243611.9
ENST00000367076.7
C4BPB
complement component 4 binding protein beta
chr10_-_50885619 0.03 ENST00000373997.8
A1CF
APOBEC1 complementation factor
chr4_+_154563003 0.03 ENST00000302068.9
ENST00000509493.1
FGB
fibrinogen beta chain
chr2_+_233718734 0.03 ENST00000373409.8
UGT1A4
UDP glucuronosyltransferase family 1 member A4
chr12_+_69738853 0.03 ENST00000247833.12
ENST00000378815.10
ENST00000483530.6
RAB3IP
RAB3A interacting protein
chr2_-_74328166 0.03 ENST00000358683.8
SLC4A5
solute carrier family 4 member 5
chr6_+_25754699 0.03 ENST00000439485.6
ENST00000377905.9
SLC17A4
solute carrier family 17 member 4
chr2_-_162074050 0.03 ENST00000676768.1
DPP4
dipeptidyl peptidase 4
chr16_+_20763990 0.03 ENST00000289416.10
ACSM3
acyl-CoA synthetase medium chain family member 3
chr13_+_27251545 0.03 ENST00000311549.11
RPL21
ribosomal protein L21
chr21_-_18403754 0.03 ENST00000284885.8
TMPRSS15
transmembrane serine protease 15
chr5_+_141182369 0.03 ENST00000609684.3
ENST00000625044.1
ENST00000623407.1
ENST00000623884.1
PCDHB16
ENSG00000279068.1
protocadherin beta 16
novel transcript
chr12_-_56221701 0.03 ENST00000615206.4
ENST00000549038.5
ENST00000552244.5
RNF41
ring finger protein 41
chr2_+_233712905 0.02 ENST00000373414.4
UGT1A5
UDP glucuronosyltransferase family 1 member A5
chrX_-_124963768 0.02 ENST00000371130.7
ENST00000422452.2
TENM1
teneurin transmembrane protein 1
chr20_+_58839712 0.02 ENST00000313949.11
GNAS
GNAS complex locus

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
1.1 4.3 GO:0000023 maltose metabolic process(GO:0000023)
1.1 7.4 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.9 5.2 GO:0002005 angiotensin catabolic process in blood(GO:0002005) angiotensin-mediated drinking behavior(GO:0003051)
0.5 2.5 GO:0044245 polysaccharide digestion(GO:0044245)
0.5 1.4 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.4 1.2 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.4 4.5 GO:0006824 cobalt ion transport(GO:0006824)
0.3 0.9 GO:0035691 macrophage migration inhibitory factor signaling pathway(GO:0035691)
0.2 1.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.2 0.8 GO:0001080 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.2 0.8 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.2 1.8 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.2 2.3 GO:0006069 ethanol oxidation(GO:0006069)
0.1 0.4 GO:0034147 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
0.1 0.8 GO:0051958 methotrexate transport(GO:0051958)
0.1 0.5 GO:2000722 negative regulation of vascular smooth muscle cell differentiation(GO:1905064) regulation of cardiac vascular smooth muscle cell differentiation(GO:2000722)
0.1 0.2 GO:0060516 primary prostatic bud elongation(GO:0060516)
0.1 0.7 GO:1904970 brush border assembly(GO:1904970)
0.1 0.6 GO:0032431 diacylglycerol biosynthetic process(GO:0006651) activation of phospholipase A2 activity(GO:0032431)
0.1 0.5 GO:0070560 protein secretion by platelet(GO:0070560)
0.1 0.4 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 1.6 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 0.3 GO:0043126 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.1 0.5 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.2 GO:0048867 stem cell fate determination(GO:0048867)
0.1 0.4 GO:0051552 flavone metabolic process(GO:0051552)
0.1 0.3 GO:0051801 cytolysis in other organism involved in symbiotic interaction(GO:0051801)
0.1 0.5 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.3 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.0 0.3 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.2 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.7 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.3 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.4 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0 0.3 GO:1903027 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.0 0.1 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.0 0.1 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.5 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.1 GO:0036233 glycine import(GO:0036233)
0.0 0.2 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.1 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0 0.2 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.2 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.4 GO:0015866 ADP transport(GO:0015866)
0.0 1.7 GO:0010107 potassium ion import(GO:0010107)
0.0 0.3 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.2 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.8 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.9 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0016119 carotene metabolic process(GO:0016119) terpene metabolic process(GO:0042214)
0.0 0.1 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.0 1.2 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 2.5 GO:0030449 regulation of complement activation(GO:0030449)
0.0 0.7 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.4 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.0 0.1 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.0 0.6 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.2 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.6 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.2 GO:0034378 chylomicron assembly(GO:0034378)
0.0 0.1 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.1 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.0 1.1 GO:0006953 acute-phase response(GO:0006953)
0.0 0.2 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.3 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 1.8 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.0 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.0 GO:0033326 cerebrospinal fluid secretion(GO:0033326)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 7.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.6 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 0.4 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 0.7 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.2 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.5 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 4.3 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 1.1 GO:0031904 endosome lumen(GO:0031904)
0.0 0.3 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.3 GO:0045179 apical cortex(GO:0045179)
0.0 4.5 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.2 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.4 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 2.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.5 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.5 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.8 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 2.4 GO:0005902 microvillus(GO:0005902)
0.0 1.6 GO:0005771 multivesicular body(GO:0005771)
0.0 0.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 1.2 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 2.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 7.4 GO:0031750 D3 dopamine receptor binding(GO:0031750)
1.4 4.3 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
1.0 5.2 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
1.0 3.9 GO:0019770 IgG receptor activity(GO:0019770)
0.8 2.3 GO:0016160 amylase activity(GO:0016160)
0.7 3.6 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.3 4.5 GO:0031419 cobalamin binding(GO:0031419)
0.3 1.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.3 1.4 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.3 2.3 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.2 1.9 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.2 0.8 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.2 0.8 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.4 GO:0052854 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.1 0.8 GO:0015350 methotrexate transporter activity(GO:0015350)
0.1 1.6 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 0.6 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 1.8 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 1.2 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.4 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.1 0.2 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.1 0.8 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 1.8 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.1 0.2 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.1 0.5 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 0.3 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.2 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.3 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.3 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.2 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.1 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 3.2 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.5 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.1 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.2 GO:0051373 FATZ binding(GO:0051373)
0.0 0.4 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.2 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.7 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.3 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.2 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.5 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 1.0 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.8 GO:0008009 chemokine activity(GO:0008009)
0.0 0.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.6 GO:0004364 glutathione transferase activity(GO:0004364)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.6 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.1 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 1.2 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.7 PID CD40 PATHWAY CD40/CD40L signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 9.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.2 2.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.2 3.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 2.9 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 1.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 1.8 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.1 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 1.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.6 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.3 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.8 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation