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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for HNF4A

Z-value: 0.70

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Transcription factors associated with HNF4A

Gene Symbol Gene ID Gene Info
ENSG00000101076.18 HNF4A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HNF4Ahg38_v1_chr20_+_44355692_44355805-0.383.6e-02Click!

Activity profile of HNF4A motif

Sorted Z-values of HNF4A motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HNF4A

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr10_-_59753388 3.26 ENST00000430431.5
myoregulin
chr20_-_7940444 2.87 ENST00000378789.4
hydroxyacid oxidase 1
chr10_-_59753444 2.48 ENST00000594536.5
ENST00000414264.6
myoregulin
chr19_+_41088450 2.32 ENST00000330436.4
cytochrome P450 family 2 subfamily A member 13
chr12_+_55681647 1.97 ENST00000614691.1
methyltransferase like 7B
chr12_+_55681711 1.96 ENST00000394252.4
methyltransferase like 7B
chr2_-_27890348 1.80 ENST00000302188.8
ribokinase
chr6_+_116616467 1.67 ENST00000229554.10
ENST00000368581.8
ENST00000368580.4
radial spoke head component 4A
chr11_+_60699605 1.66 ENST00000300226.7
membrane spanning 4-domains A8
chr2_-_158456702 1.37 ENST00000409889.1
ENST00000283233.10
coiled-coil domain containing 148
chr1_+_61082702 1.24 ENST00000485903.6
ENST00000371185.6
ENST00000371184.6
nuclear factor I A
chr16_-_16223467 1.20 ENST00000575728.1
ENST00000574094.6
ENST00000205557.12
ATP binding cassette subfamily C member 6
chr9_+_128460559 1.18 ENST00000372807.9
ENST00000444119.6
outer dense fiber of sperm tails 2
chr5_-_16508788 1.15 ENST00000682142.1
reticulophagy regulator 1
chr10_-_17129786 1.14 ENST00000377833.10
cubilin
chr19_+_4639505 1.14 ENST00000327473.9
TNF alpha induced protein 8 like 1
chr5_-_16508990 1.13 ENST00000399793.6
reticulophagy regulator 1
chr17_-_37745018 1.03 ENST00000613727.4
ENST00000614313.4
ENST00000617811.5
ENST00000621123.4
HNF1 homeobox B
chr1_+_61082398 0.95 ENST00000664149.1
nuclear factor I A
chr17_+_7688427 0.95 ENST00000396463.7
ENST00000534050.5
WD repeat containing antisense to TP53
chr2_-_74421560 0.90 ENST00000612891.4
ENST00000640331.1
ENST00000684111.1
chromosome 2 open reading frame 81
chr16_+_19417875 0.90 ENST00000542583.7
transmembrane channel like 5
chr10_+_94762673 0.88 ENST00000480405.2
ENST00000371321.9
cytochrome P450 family 2 subfamily C member 19
chr12_-_39443390 0.87 ENST00000361961.7
kinesin family member 21A
chr14_+_22883220 0.85 ENST00000536884.1
ENST00000267396.9
RRAD and GEM like GTPase 2
chr1_-_197067234 0.84 ENST00000367412.2
coagulation factor XIII B chain
chr1_-_177970213 0.84 ENST00000464631.6
SEC16 homolog B, endoplasmic reticulum export factor
chr1_+_61082553 0.81 ENST00000403491.8
ENST00000371187.7
nuclear factor I A
chr16_+_66844408 0.72 ENST00000338437.7
carbonic anhydrase 7
chr10_+_94938649 0.69 ENST00000461906.1
ENST00000260682.8
cytochrome P450 family 2 subfamily C member 9
chr3_-_120682215 0.68 ENST00000283871.10
homogentisate 1,2-dioxygenase
chr2_+_74421721 0.63 ENST00000409791.5
ENST00000348227.4
WD repeat domain 54
chr5_+_90899183 0.62 ENST00000640815.1
adhesion G protein-coupled receptor V1
chr11_+_27055215 0.60 ENST00000525090.1
gamma-butyrobetaine hydroxylase 1
chr11_+_63369779 0.58 ENST00000279178.4
solute carrier family 22 member 9
chr5_-_42811884 0.57 ENST00000514985.6
ENST00000511224.5
ENST00000507920.5
ENST00000510965.1
selenoprotein P
chr11_+_1834804 0.57 ENST00000341958.3
synaptotagmin 8
chr2_+_240605417 0.53 ENST00000319838.10
ENST00000403859.1
G protein-coupled receptor 35
chr10_+_94683771 0.53 ENST00000339022.6
cytochrome P450 family 2 subfamily C member 18
chr7_-_78771265 0.53 ENST00000630991.2
ENST00000629359.2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr11_-_123885627 0.52 ENST00000528595.1
ENST00000375026.7
transmembrane protein 225
chr11_+_118998126 0.51 ENST00000334418.6
centrosomal AT-AC splicing factor
chr5_-_16508858 0.51 ENST00000684456.1
reticulophagy regulator 1
chr10_+_94683722 0.50 ENST00000285979.11
cytochrome P450 family 2 subfamily C member 18
chr1_-_43285559 0.49 ENST00000523677.6
chromosome 1 open reading frame 210
chr13_-_52011337 0.49 ENST00000400366.6
ENST00000400370.8
ENST00000634844.1
ENST00000673772.1
ENST00000418097.7
ENST00000242839.10
ENST00000344297.9
ENST00000448424.7
ATPase copper transporting beta
chr14_-_75980993 0.49 ENST00000556285.1
transforming growth factor beta 3
chr10_-_114684612 0.49 ENST00000533213.6
ENST00000369252.8
actin binding LIM protein 1
chr5_-_16508951 0.49 ENST00000682628.1
reticulophagy regulator 1
chr5_+_80654644 0.48 ENST00000265081.7
mutS homolog 3
chr5_-_16508812 0.48 ENST00000683414.1
reticulophagy regulator 1
chr16_+_66844914 0.47 ENST00000394069.3
carbonic anhydrase 7
chr14_+_77181780 0.46 ENST00000298351.5
ENST00000554346.5
transmembrane protein 63C
chr1_+_180632001 0.45 ENST00000367590.9
ENST00000367589.3
xenotropic and polytropic retrovirus receptor 1
chr6_+_46793379 0.44 ENST00000230588.9
ENST00000611727.2
meprin A subunit alpha
chr11_+_1834415 0.43 ENST00000381968.7
ENST00000381978.7
synaptotagmin 8
chr3_-_9878765 0.42 ENST00000430427.6
ENST00000383817.5
ENST00000679265.1
cell death inducing DFFA like effector c
chr7_+_120988683 0.40 ENST00000340646.9
ENST00000310396.10
cadherin like and PC-esterase domain containing 1
chr16_+_83998252 0.39 ENST00000564166.1
N-terminal EF-hand calcium binding protein 2
chr1_+_241532121 0.39 ENST00000366558.7
kynurenine 3-monooxygenase
chr3_-_194351290 0.39 ENST00000429275.1
ENST00000323830.4
carboxypeptidase N subunit 2
chr13_+_113105782 0.39 ENST00000541084.5
ENST00000346342.8
ENST00000375581.3
coagulation factor VII
chr2_+_61162185 0.38 ENST00000432605.3
ENST00000488469.4
chromosome 2 open reading frame 74
chr3_+_63912588 0.36 ENST00000522345.2
ataxin 7
chr2_-_62506136 0.35 ENST00000335390.6
transmembrane protein 17
chr19_-_48363914 0.34 ENST00000377431.6
ENST00000293261.8
transmembrane protein 143
chr14_+_100019375 0.33 ENST00000544450.6
Enah/Vasp-like
chr20_-_45857196 0.33 ENST00000457981.5
ENST00000426915.1
ENST00000217455.9
acyl-CoA thioesterase 8
chr15_+_51341648 0.33 ENST00000335449.11
ENST00000560215.5
gliomedin
chrX_-_53281524 0.33 ENST00000498281.2
IQ motif and Sec7 domain ArfGEF 2
chr12_+_108880085 0.32 ENST00000228476.8
ENST00000547768.5
D-amino acid oxidase
chr1_-_161223408 0.32 ENST00000491350.1
apolipoprotein A2
chr20_+_59300402 0.31 ENST00000311585.11
ENST00000371028.6
endothelin 3
chr2_+_119679184 0.31 ENST00000445518.1
ENST00000272521.7
ENST00000409951.1
transmembrane protein 177
chr6_+_30163541 0.31 ENST00000376694.9
tripartite motif containing 15
chr15_-_40828699 0.30 ENST00000299174.10
ENST00000427255.2
protein phosphatase 1 regulatory inhibitor subunit 14D
chr2_-_221572272 0.29 ENST00000409854.5
ENST00000443796.5
ENST00000281821.7
EPH receptor A4
chr3_+_108822759 0.29 ENST00000426646.1
T cell receptor associated transmembrane adaptor 1
chr19_+_44946043 0.29 ENST00000252490.7
ENST00000591597.5
apolipoprotein C2
chr3_+_108822778 0.29 ENST00000295756.11
T cell receptor associated transmembrane adaptor 1
chr17_+_29043124 0.29 ENST00000323372.9
pipecolic acid and sarcosine oxidase
chr1_-_177969907 0.29 ENST00000308284.10
SEC16 homolog B, endoplasmic reticulum export factor
chr11_-_10294194 0.29 ENST00000676387.1
ENST00000256190.13
ENST00000675281.1
SET binding factor 2
chr2_+_119679154 0.28 ENST00000401466.5
ENST00000424086.5
transmembrane protein 177
chr19_-_48364034 0.28 ENST00000435956.7
transmembrane protein 143
chr2_-_218568291 0.28 ENST00000418019.5
ENST00000454775.5
ENST00000338465.5
ENST00000415516.5
ENST00000258399.8
ubiquitin specific peptidase 37
chr22_+_24607638 0.27 ENST00000432867.5
gamma-glutamyltransferase 1
chr1_+_196888014 0.27 ENST00000367416.6
ENST00000608469.6
ENST00000251424.8
ENST00000367418.2
complement factor H related 4
chr6_+_143677935 0.27 ENST00000440869.6
ENST00000367582.7
ENST00000451827.6
phosphatase and actin regulator 2
chr1_-_15585015 0.27 ENST00000375826.4
agmatinase
chr17_+_4771878 0.26 ENST00000270560.4
transmembrane 4 L six family member 5
chr22_-_30667795 0.26 ENST00000404885.5
ENST00000403268.1
ENST00000407308.1
ENST00000334679.4
ENST00000342474.4
dual specificity phosphatase 18
chr20_+_57561103 0.26 ENST00000319441.6
phosphoenolpyruvate carboxykinase 1
chr11_-_74009077 0.24 ENST00000314032.9
ENST00000426995.2
uncoupling protein 3
chr16_+_24846231 0.24 ENST00000568579.5
ENST00000567758.5
ENST00000569071.1
solute carrier family 5 member 11
chr19_-_10577231 0.24 ENST00000589348.1
ENST00000592285.1
ENST00000587069.5
adaptor related protein complex 1 subunit mu 2
chr1_+_94418435 0.24 ENST00000647998.2
ATP binding cassette subfamily D member 3
chr2_+_10302867 0.23 ENST00000423674.5
ENST00000307845.8
hippocalcin like 1
chr2_+_218568558 0.23 ENST00000627282.2
ENST00000542068.5
CCR4-NOT transcription complex subunit 9
chr16_+_24845841 0.23 ENST00000347898.7
ENST00000545376.5
ENST00000449109.6
ENST00000424767.6
solute carrier family 5 member 11
chr16_+_24845987 0.22 ENST00000565769.5
ENST00000569520.5
solute carrier family 5 member 11
chr11_-_707063 0.22 ENST00000683307.1
DEAF1 transcription factor
chr7_-_78771108 0.22 ENST00000626691.2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr3_-_49813880 0.22 ENST00000333486.4
ubiquitin like modifier activating enzyme 7
chr17_+_43780425 0.21 ENST00000449302.8
CFAP97 domain containing 1
chr1_+_43389889 0.21 ENST00000562955.2
ENST00000634258.3
SZT2 subunit of KICSTOR complex
chr19_+_46303599 0.21 ENST00000300862.7
hypoxia inducible factor 3 subunit alpha
chr1_+_94418375 0.20 ENST00000370214.9
ATP binding cassette subfamily D member 3
chr16_+_81238682 0.20 ENST00000258168.7
ENST00000564552.1
beta-carotene oxygenase 1
chr18_+_56651335 0.20 ENST00000589935.1
ENST00000254442.8
ENST00000357574.7
WD repeat domain 7
chr3_+_63911929 0.20 ENST00000487717.5
ataxin 7
chr9_+_27109135 0.20 ENST00000519097.5
ENST00000615002.4
TEK receptor tyrosine kinase
chr10_-_95069489 0.20 ENST00000371270.6
ENST00000535898.5
ENST00000623108.3
cytochrome P450 family 2 subfamily C member 8
chrX_-_43882411 0.19 ENST00000378069.5
monoamine oxidase B
chr2_+_218568809 0.19 ENST00000273064.11
CCR4-NOT transcription complex subunit 9
chr2_+_44275457 0.19 ENST00000611973.4
ENST00000409387.5
solute carrier family 3 member 1
chr1_+_6448022 0.19 ENST00000416731.5
ENST00000461727.6
espin
chr5_-_35047935 0.18 ENST00000510428.1
ENST00000231420.11
alanine--glyoxylate aminotransferase 2
chr2_+_158456939 0.18 ENST00000389759.8
ENST00000628904.2
ENST00000389757.7
plakophilin 4
chr3_+_124094663 0.18 ENST00000460856.5
ENST00000240874.7
kalirin RhoGEF kinase
chr2_+_27890716 0.18 ENST00000344773.6
ENST00000379624.6
ENST00000342045.6
ENST00000379632.6
ENST00000361704.6
BRISC and BRCA1 A complex member 2
chr16_-_88686453 0.18 ENST00000332281.6
snail family transcriptional repressor 3
chr9_+_27109200 0.18 ENST00000380036.10
TEK receptor tyrosine kinase
chr6_+_79631322 0.17 ENST00000369838.6
SH3 domain binding glutamate rich protein like 2
chr6_-_29375291 0.17 ENST00000396806.3
olfactory receptor family 12 subfamily D member 3
chrX_+_118974608 0.17 ENST00000304778.11
ENST00000371628.8
LON peptidase N-terminal domain and ring finger 3
chr3_+_119782094 0.16 ENST00000393716.8
nuclear receptor subfamily 1 group I member 2
chr1_-_27366917 0.16 ENST00000357582.3
mitogen-activated protein kinase kinase kinase 6
chr17_+_75610690 0.16 ENST00000642007.1
myosin XVB
chr17_-_2711633 0.16 ENST00000435359.5
clustered mitochondria homolog
chr12_-_45990519 0.16 ENST00000266589.10
ENST00000369367.8
ENST00000395453.2
ENST00000395454.6
SR-related CTD associated factor 11
chr22_+_24607658 0.16 ENST00000451366.5
ENST00000428855.5
gamma-glutamyltransferase 1
chr19_-_14062028 0.16 ENST00000669674.2
paralemmin 3
chr19_+_39391323 0.15 ENST00000615911.4
ENST00000315588.11
ENST00000594368.5
ENST00000596297.1
mediator complex subunit 29
chr3_-_187291680 0.15 ENST00000425937.1
ENST00000337774.10
ENST00000296280.11
mannan binding lectin serine peptidase 1
chr3_+_124094696 0.15 ENST00000360013.7
ENST00000684186.1
ENST00000684276.1
kalirin RhoGEF kinase
chr20_+_59300547 0.15 ENST00000644821.1
endothelin 3
chr8_+_95024977 0.14 ENST00000396124.9
NADH:ubiquinone oxidoreductase complex assembly factor 6
chr14_+_23185316 0.14 ENST00000399910.5
ENST00000492621.5
ring finger protein 212B
chr17_+_28744034 0.14 ENST00000444415.7
ENST00000262396.10
TNF receptor associated factor 4
chr10_-_20897288 0.13 ENST00000377122.9
nebulette
chr1_+_241532370 0.13 ENST00000366559.9
ENST00000366557.8
kynurenine 3-monooxygenase
chr20_+_59300589 0.13 ENST00000337938.7
ENST00000371025.7
endothelin 3
chr3_-_9878488 0.13 ENST00000443115.1
cell death inducing DFFA like effector c
chr17_+_79730937 0.13 ENST00000328313.10
ectonucleotide pyrophosphatase/phosphodiesterase 7
chr3_-_124934735 0.13 ENST00000478191.1
ENST00000616727.4
mucin 13, cell surface associated
chr18_+_56651385 0.12 ENST00000615645.4
WD repeat domain 7
chr6_-_73520441 0.12 ENST00000615060.5
eukaryotic translation elongation factor 1 alpha 1
chr6_+_30163188 0.12 ENST00000619857.4
tripartite motif containing 15
chr15_-_73633310 0.12 ENST00000345330.9
neuroplastin
chr16_+_31033781 0.12 ENST00000613541.1
syntaxin 4
chr19_-_7632971 0.12 ENST00000598935.5
Purkinje cell protein 2
chr12_+_67269328 0.11 ENST00000545606.6
cullin associated and neddylation dissociated 1
chr6_-_149484965 0.11 ENST00000409806.8
zinc finger CCCH-type containing 12D
chr2_-_179049986 0.11 ENST00000409284.1
ENST00000443758.6
ENST00000446116.5
coiled-coil domain containing 141
chr15_+_81196871 0.11 ENST00000559383.5
ENST00000394660.6
ENST00000683961.1
interleukin 16
chr6_+_32014795 0.11 ENST00000435363.7
ENST00000425700.3
complement C4B (Chido blood group)
chr2_+_218270392 0.11 ENST00000248451.7
ENST00000273077.9
PNKD metallo-beta-lactamase domain containing
chr22_+_29767351 0.11 ENST00000330029.6
ENST00000401406.3
ubiquinol-cytochrome c reductase, complex III subunit X
chr6_+_31982057 0.10 ENST00000428956.7
ENST00000498271.1
complement C4A (Rodgers blood group)
chr22_+_24607602 0.10 ENST00000447416.5
gamma-glutamyltransferase 1
chr13_+_75760362 0.10 ENST00000534657.5
LIM domain 7
chr12_-_7018465 0.10 ENST00000261407.9
lysophosphatidylcholine acyltransferase 3
chr3_-_126056786 0.10 ENST00000383598.6
solute carrier family 41 member 3
chr9_-_136944725 0.10 ENST00000325285.8
F-box and WD repeat domain containing 5
chr9_+_137230757 0.09 ENST00000673865.1
ENST00000538474.5
ENST00000673835.1
ENST00000673953.1
ENST00000361134.2
solute carrier family 34 member 3
chr19_+_10086787 0.09 ENST00000590378.5
ENST00000397881.7
shiftless antiviral inhibitor of ribosomal frameshifting
chr17_+_45962338 0.09 ENST00000415613.6
ENST00000420682.6
ENST00000431008.7
ENST00000571987.5
ENST00000574436.5
microtubule associated protein tau
chr2_+_14632688 0.08 ENST00000331243.4
ENST00000295092.3
LRAT domain containing 1
chr11_-_45917867 0.08 ENST00000378750.10
peroxisomal biogenesis factor 16
chr10_-_102120246 0.08 ENST00000425280.2
LIM domain binding 1
chr20_-_3663399 0.08 ENST00000290417.7
ENST00000319242.8
GDNF family receptor alpha 4
chr9_-_113303271 0.08 ENST00000297894.5
ENST00000489339.2
ring finger protein 183
chr5_-_32444722 0.07 ENST00000265069.13
zinc finger RNA binding protein
chr3_-_42875871 0.07 ENST00000316161.6
ENST00000437102.1
cytochrome P450 family 8 subfamily B member 1
chr12_+_53103479 0.07 ENST00000301466.8
ENST00000551896.5
sterol O-acyltransferase 2
chr6_-_73520170 0.07 ENST00000678508.1
eukaryotic translation elongation factor 1 alpha 1
chr10_+_102644462 0.07 ENST00000643721.2
ENST00000302424.12
tripartite motif containing 8
chr12_-_51028234 0.07 ENST00000547688.7
ENST00000394904.9
solute carrier family 11 member 2
chr17_+_63477052 0.07 ENST00000290866.10
ENST00000428043.5
angiotensin I converting enzyme
chr15_-_99733339 0.07 ENST00000409796.5
ENST00000344791.6
ENST00000684762.1
ENST00000450512.1
ENST00000545021.2
ENST00000332728.8
LysM domain containing 4
chrX_+_154429092 0.06 ENST00000619046.5
ATPase H+ transporting accessory protein 1
chr20_+_38033719 0.06 ENST00000373433.9
regulation of nuclear pre-mRNA domain containing 1B
chr2_-_218270099 0.06 ENST00000248450.9
ENST00000444053.5
angio associated migratory cell protein
chr12_+_55720405 0.06 ENST00000548082.1
retinol dehydrogenase 5
chr7_-_15561986 0.06 ENST00000342526.8
alkylglycerol monooxygenase
chr14_+_64214136 0.05 ENST00000557084.1
ENST00000458046.6
spectrin repeat containing nuclear envelope protein 2
chr2_-_218269619 0.05 ENST00000447885.1
ENST00000420660.5
angio associated migratory cell protein
chr9_-_15307181 0.05 ENST00000506891.1
ENST00000512701.6
ENST00000380850.8
ENST00000297615.9
tetratricopeptide repeat domain 39B
chr18_+_59225492 0.05 ENST00000456142.3
ENST00000530323.1
gastrin releasing peptide
chr16_+_21233672 0.05 ENST00000311620.7
ankyrin repeat and sterile alpha motif domain containing 4B
chr5_+_73173186 0.05 ENST00000296776.6
transmembrane protein 174
chr14_+_23321446 0.05 ENST00000216727.9
ENST00000397276.6
poly(A) binding protein nuclear 1
chr6_+_31946086 0.04 ENST00000425368.7
complement factor B
chr6_-_31958852 0.04 ENST00000375425.9
ENST00000426722.5
negative elongation factor complex member E
chr14_+_22207502 0.04 ENST00000390461.2
T cell receptor alpha variable 34
chr20_+_59300703 0.04 ENST00000395654.3
endothelin 3
chr19_-_39391137 0.03 ENST00000595564.5
PAF1 homolog, Paf1/RNA polymerase II complex component
chr17_-_2711736 0.03 ENST00000651024.2
ENST00000576885.5
ENST00000574426.7
clustered mitochondria homolog
chr8_+_103819244 0.03 ENST00000262231.14
ENST00000507740.5
ENST00000408894.6
regulating synaptic membrane exocytosis 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 5.7 GO:1902081 regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.6 1.8 GO:0019303 D-ribose catabolic process(GO:0019303)
0.5 3.7 GO:0061709 reticulophagy(GO:0061709)
0.4 2.9 GO:0009441 glycolate metabolic process(GO:0009441)
0.3 2.1 GO:0009804 coumarin metabolic process(GO:0009804)
0.3 1.6 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.3 1.0 GO:0039020 pronephric nephron tubule development(GO:0039020) hepatoblast differentiation(GO:0061017)
0.2 1.2 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.2 0.8 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 0.5 GO:0060003 copper ion export(GO:0060003)
0.2 0.5 GO:0003032 detection of oxygen(GO:0003032)
0.1 0.4 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.1 0.9 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.1 0.3 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.1 0.5 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 0.4 GO:1904021 negative regulation of G-protein coupled receptor internalization(GO:1904021)
0.1 0.7 GO:0015798 myo-inositol transport(GO:0015798)
0.1 0.3 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.1 0.4 GO:0033594 response to hydroxyisoflavone(GO:0033594)
0.1 3.0 GO:0072189 ureter development(GO:0072189)
0.1 0.4 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 0.3 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
0.1 0.5 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.6 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.1 0.7 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 1.1 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.1 0.3 GO:0019474 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.1 1.2 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 0.3 GO:2000327 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.1 0.7 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.1 0.9 GO:0015889 cobalamin transport(GO:0015889)
0.1 0.6 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 0.6 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.6 GO:0015747 urate transport(GO:0015747)
0.1 0.5 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.1 0.2 GO:0016119 carotene metabolic process(GO:0016119)
0.0 0.4 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.6 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.2 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.0 0.3 GO:1901162 primary amino compound biosynthetic process(GO:1901162)
0.0 0.5 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.1 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.5 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 0.3 GO:0046959 habituation(GO:0046959) negative regulation of growth hormone secretion(GO:0060125)
0.0 0.3 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.0 0.2 GO:0014063 response to aluminum ion(GO:0010044) negative regulation of serotonin secretion(GO:0014063)
0.0 0.2 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.0 0.1 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.0 0.2 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.3 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 1.7 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.5 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.3 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 1.0 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.3 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.2 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.0 0.0 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.0 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.2 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.9 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.1 GO:0015692 lead ion transport(GO:0015692)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.2 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 0.2 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.0 0.0 GO:0034183 negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0001534 radial spoke(GO:0001534)
0.2 1.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 0.5 GO:0032302 MutSbeta complex(GO:0032302)
0.1 5.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 1.2 GO:0001520 outer dense fiber(GO:0001520)
0.1 4.2 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 3.7 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.6 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.6 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.9 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.2 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.2 GO:0070552 BRISC complex(GO:0070552)
0.0 0.6 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.5 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.1 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.3 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.2 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.9 GO:0005871 kinesin complex(GO:0005871)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0003973 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.3 5.1 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.2 0.6 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.2 0.5 GO:0004008 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.1 0.4 GO:0031687 A2A adenosine receptor binding(GO:0031687)
0.1 0.4 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.3 GO:0052815 medium-chain acyl-CoA hydrolase activity(GO:0052815) long-chain acyl-CoA hydrolase activity(GO:0052816)
0.1 0.6 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.5 GO:0000406 double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.1 0.7 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.3 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.1 0.5 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 1.1 GO:0031419 cobalamin binding(GO:0031419)
0.1 1.2 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.1 0.2 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 1.1 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.3 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1 0.9 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 0.7 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 0.6 GO:0008430 selenium binding(GO:0008430)
0.0 0.5 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.5 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 1.8 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.2 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.0 0.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.6 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.5 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.3 GO:0042731 PH domain binding(GO:0042731)
0.0 0.9 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.1 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.1 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.1 GO:0099609 microtubule lateral binding(GO:0099609)
0.0 0.5 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.2 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.5 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.1 GO:0015639 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.1 GO:0070573 tripeptidyl-peptidase activity(GO:0008240) peptidyl-dipeptidase activity(GO:0008241) bradykinin receptor binding(GO:0031711) metallodipeptidase activity(GO:0070573)
0.0 0.1 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 1.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.0 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 3.1 GO:0008168 methyltransferase activity(GO:0008168)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 4.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.2 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.5 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.9 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 1.1 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.8 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.9 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 1.6 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.9 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 4.9 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.6 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.5 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.3 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.6 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling