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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for HOXA1

Z-value: 0.74

Motif logo

Transcription factors associated with HOXA1

Gene Symbol Gene ID Gene Info
ENSG00000105991.10 HOXA1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXA1hg38_v1_chr7_-_27095972_27096039-0.193.1e-01Click!

Activity profile of HOXA1 motif

Sorted Z-values of HOXA1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr22_-_30470577 4.98 ENST00000435069.1
ENST00000540910.5
SEC14 like lipid binding 3
chr16_+_83968244 4.64 ENST00000305202.9
N-terminal EF-hand calcium binding protein 2
chr8_+_103140692 2.62 ENST00000438105.2
ENST00000309982.10
ENST00000297574.6
BAALC binder of MAP3K1 and KLF4
chrX_-_1212634 1.64 ENST00000381567.8
ENST00000381566.6
ENST00000400841.8
cytokine receptor like factor 2
chr1_+_85062304 1.39 ENST00000326813.12
ENST00000528899.5
ENST00000294664.11
dynein axonemal intermediate chain 3
chr3_-_112845950 1.36 ENST00000398214.5
CD200 receptor 1 like
chr15_-_93073111 1.24 ENST00000557420.1
ENST00000542321.6
repulsive guidance molecule BMP co-receptor a
chr3_+_98353854 1.13 ENST00000354924.2
olfactory receptor family 5 subfamily K member 4
chr10_-_27981805 0.98 ENST00000673512.1
ENST00000672877.1
ENST00000480504.1
outer dynein arm docking complex subunit 2
chr14_+_96482982 0.96 ENST00000554706.1
adenylate kinase 7
chr8_-_27258414 0.95 ENST00000523048.5
stathmin 4
chr8_-_27611325 0.92 ENST00000523500.5
clusterin
chr15_+_81299416 0.91 ENST00000558332.3
interleukin 16
chr8_-_27611424 0.85 ENST00000405140.7
clusterin
chr2_-_152098810 0.84 ENST00000636442.1
ENST00000638005.1
calcium voltage-gated channel auxiliary subunit beta 4
chrX_+_135309480 0.80 ENST00000635820.1
embryonic testis differentiation homolog C
chr1_+_18630839 0.78 ENST00000420770.7
paired box 7
chr17_+_70075215 0.76 ENST00000283936.5
ENST00000615244.4
ENST00000392671.6
potassium inwardly rectifying channel subfamily J member 16
chr13_+_35476740 0.74 ENST00000537702.5
neurobeachin
chr13_-_35476682 0.71 ENST00000379919.6
mab-21 like 1
chr19_-_54242751 0.71 ENST00000245621.6
ENST00000396365.6
leukocyte immunoglobulin like receptor A6
chr16_+_2988256 0.68 ENST00000573315.2
long intergenic non-protein coding RNA 514
chr6_-_31684040 0.66 ENST00000375863.7
lymphocyte antigen 6 family member G5C
chr9_+_36136416 0.66 ENST00000396613.7
GLI pathogenesis related 2
chr4_-_137532452 0.65 ENST00000412923.6
ENST00000511115.5
ENST00000344876.9
ENST00000507846.5
ENST00000510305.5
ENST00000611581.1
protocadherin 18
chr9_-_35563867 0.64 ENST00000399742.7
ENST00000619051.4
family with sequence similarity 166 member B
chr8_-_27605271 0.63 ENST00000522098.1
clusterin
chr22_+_25219633 0.62 ENST00000398215.3
crystallin beta B2
chr2_-_153478753 0.61 ENST00000325926.4
reprimo, TP53 dependent G2 arrest mediator homolog
chr1_+_3698027 0.60 ENST00000378290.4
tumor protein p73
chr11_-_5227063 0.60 ENST00000335295.4
ENST00000485743.1
ENST00000647020.1
hemoglobin subunit beta
chr5_-_134367144 0.59 ENST00000265334.9
cyclin dependent kinase like 3
chr16_-_67393486 0.57 ENST00000562206.1
ENST00000393957.7
ENST00000290942.9
tubulin polymerization promoting protein family member 3
chr12_+_8123899 0.56 ENST00000641376.1
C-type lectin domain family 4 member A
chrX_+_129779930 0.55 ENST00000356892.4
SAM and SH3 domain containing 3
chr12_-_101210232 0.53 ENST00000536262.3
solute carrier family 5 member 8
chr6_+_25754699 0.53 ENST00000439485.6
ENST00000377905.9
solute carrier family 17 member 4
chrX_+_15507302 0.52 ENST00000342014.6
BMX non-receptor tyrosine kinase
chr17_+_28473278 0.52 ENST00000444914.7
solute carrier family 13 member 2
chr10_-_87863533 0.49 ENST00000445946.5
killin, p53 regulated DNA replication inhibitor
chr9_-_5304713 0.46 ENST00000381627.4
relaxin 2
chr11_+_125904467 0.46 ENST00000263576.11
ENST00000530414.5
ENST00000530129.6
DEAD-box helicase 25
chr20_-_31870629 0.45 ENST00000375966.8
ENST00000278979.7
dual specificity phosphatase 15
chr7_-_117323041 0.45 ENST00000491214.1
ENST00000265441.8
Wnt family member 2
chr2_-_79086847 0.45 ENST00000454188.5
regenerating family member 1 beta
chr11_+_34438900 0.44 ENST00000241052.5
catalase
chr9_-_10612966 0.43 ENST00000381196.9
protein tyrosine phosphatase receptor type D
chr20_-_25058115 0.43 ENST00000323482.9
acyl-CoA synthetase short chain family member 1
chr10_+_7703340 0.42 ENST00000429820.5
ENST00000379587.4
inter-alpha-trypsin inhibitor heavy chain 2
chr10_+_7703300 0.42 ENST00000358415.9
inter-alpha-trypsin inhibitor heavy chain 2
chr11_-_40294089 0.42 ENST00000278198.2
leucine rich repeat containing 4C
chr16_+_25216943 0.41 ENST00000219660.6
aquaporin 8
chr7_-_137343688 0.41 ENST00000348225.7
pleiotrophin
chr7_-_137343752 0.41 ENST00000393083.2
pleiotrophin
chr15_-_52295792 0.41 ENST00000261839.12
myosin VC
chr5_-_137735997 0.39 ENST00000505853.1
kelch like family member 3
chr11_-_5441514 0.38 ENST00000380211.1
olfactory receptor family 51 subfamily I member 1
chr15_-_43220989 0.38 ENST00000540029.5
ENST00000441366.7
ENST00000648595.1
erythrocyte membrane protein band 4.2
chr13_+_111114550 0.38 ENST00000317133.9
Rho guanine nucleotide exchange factor 7
chr9_+_2717479 0.37 ENST00000382082.4
potassium voltage-gated channel modifier subfamily V member 2
chr7_+_120988683 0.36 ENST00000340646.9
ENST00000310396.10
cadherin like and PC-esterase domain containing 1
chr19_-_49020523 0.35 ENST00000637680.1
novel protein
chr17_+_62370218 0.35 ENST00000450662.7
EF-hand calcium binding domain 3
chr12_+_75334675 0.34 ENST00000312442.2
GLIPR1 like 1
chr1_-_91886144 0.33 ENST00000212355.9
transforming growth factor beta receptor 3
chr1_+_65264694 0.33 ENST00000263441.11
ENST00000395325.7
DnaJ heat shock protein family (Hsp40) member C6
chr22_-_38794111 0.33 ENST00000406622.5
ENST00000216068.9
ENST00000406199.3
Sad1 and UNC84 domain containing 2
dynein axonemal light chain 4
chr8_+_2045058 0.32 ENST00000523438.1
myomesin 2
chr1_-_7853054 0.32 ENST00000361696.10
urotensin 2
chr1_-_182672232 0.32 ENST00000508450.5
regulator of G protein signaling 8
chr12_+_75334655 0.32 ENST00000378695.9
GLIPR1 like 1
chr21_+_31873010 0.31 ENST00000270112.7
hormonally up-regulated Neu-associated kinase
chr5_+_134526100 0.30 ENST00000395003.5
jade family PHD finger 2
chr1_+_236394268 0.30 ENST00000334232.9
EDAR associated death domain
chr13_+_29428603 0.30 ENST00000380808.6
microtubule associated scaffold protein 2
chr8_-_113436883 0.30 ENST00000455883.2
ENST00000297405.10
CUB and Sushi multiple domains 3
chr17_-_40665121 0.30 ENST00000394052.5
keratin 222
chr12_-_86256267 0.29 ENST00000620241.4
MGAT4 family member C
chr17_-_48545077 0.29 ENST00000330070.6
homeobox B2
chr4_-_38804783 0.28 ENST00000308979.7
ENST00000505940.1
ENST00000515861.5
toll like receptor 1
chr1_-_13347134 0.28 ENST00000334600.7
PRAME family member 14
chr11_-_104164361 0.28 ENST00000302251.9
platelet derived growth factor D
chr20_+_9514562 0.27 ENST00000246070.3
lysosomal associated membrane protein family member 5
chr5_-_137736066 0.27 ENST00000309755.9
kelch like family member 3
chr11_-_40293102 0.27 ENST00000527150.5
leucine rich repeat containing 4C
chr2_-_49154507 0.27 ENST00000406846.7
follicle stimulating hormone receptor
chr17_-_63972918 0.26 ENST00000435607.3
sodium voltage-gated channel alpha subunit 4
chr1_-_203229660 0.26 ENST00000255427.7
ENST00000367229.6
chitinase 1
chr5_-_20575850 0.26 ENST00000507958.5
cadherin 18
chr14_+_99684283 0.26 ENST00000261835.8
cytochrome P450 family 46 subfamily A member 1
chr14_-_80941719 0.26 ENST00000557411.5
ENST00000555265.6
centrosomal protein 128
chr1_-_110519175 0.25 ENST00000369771.4
potassium voltage-gated channel subfamily A member 10
chr11_-_104164126 0.25 ENST00000393158.7
platelet derived growth factor D
chr2_-_49154433 0.25 ENST00000454032.5
ENST00000304421.8
follicle stimulating hormone receptor
chr20_+_2692736 0.25 ENST00000380648.9
ENST00000497450.5
EBF family member 4
chr11_+_2461432 0.24 ENST00000335475.6
potassium voltage-gated channel subfamily Q member 1
chr12_+_48183602 0.23 ENST00000316554.5
coiled-coil domain containing 184
chr5_-_42825884 0.23 ENST00000506577.5
selenoprotein P
chr20_+_31870628 0.23 ENST00000375938.8
tubulin tyrosine ligase like 9
chrX_-_43973382 0.23 ENST00000642620.1
ENST00000647044.1
norrin cystine knot growth factor NDP
chr9_-_21368057 0.23 ENST00000449498.2
interferon alpha 13
chr1_-_100178215 0.23 ENST00000370138.1
ENST00000370137.6
ENST00000342895.7
ENST00000620882.4
leucine rich repeat containing 39
chr9_+_61190003 0.23 ENST00000619167.1
SPATA31 subfamily A member 7
chr22_-_19431692 0.22 ENST00000340170.8
ENST00000263208.5
histone cell cycle regulator
chr16_+_28292485 0.22 ENST00000341901.5
SH3 domain binding kinase 1
chr17_-_44199834 0.22 ENST00000587097.6
ataxin 7 like 3
chr6_-_15586006 0.22 ENST00000462989.6
dystrobrevin binding protein 1
chr5_+_134525649 0.22 ENST00000282605.8
ENST00000681547.2
ENST00000361895.6
ENST00000402835.5
jade family PHD finger 2
chr12_-_95996302 0.21 ENST00000261208.8
ENST00000538703.5
ENST00000541929.5
histidine ammonia-lyase
chr2_+_70978380 0.21 ENST00000272421.10
ENST00000441349.5
ENST00000457410.5
ankyrin repeat domain 53
chr3_+_72888031 0.21 ENST00000389617.9
glucoside xylosyltransferase 2
chr11_+_31816266 0.20 ENST00000644607.1
ENST00000646221.1
ENST00000643671.1
ENST00000643931.1
ENST00000642614.1
ENST00000642818.1
ENST00000645848.1
ENST00000506388.2
ENST00000645824.1
ENST00000532942.5
PAX6 upstream antisense RNA
novel protein
chr6_+_89562308 0.20 ENST00000522441.5
ankyrin repeat domain 6
chr2_+_1484663 0.20 ENST00000446278.5
ENST00000469607.3
thyroid peroxidase
chr1_+_100345018 0.20 ENST00000635056.2
ENST00000647005.1
cell division cycle 14A
chr6_-_41154326 0.20 ENST00000426005.6
ENST00000437044.2
ENST00000373127.8
triggering receptor expressed on myeloid cells like 1
chr16_+_75222609 0.20 ENST00000495583.1
chymotrypsinogen B1
chr18_-_76495191 0.20 ENST00000443185.7
zinc finger protein 516
chr6_+_101393699 0.19 ENST00000369134.9
ENST00000684068.1
ENST00000683903.1
ENST00000681975.1
glutamate ionotropic receptor kainate type subunit 2
chr3_-_49929800 0.19 ENST00000455683.6
MON1 homolog A, secretory trafficking associated
chr3_+_49021605 0.19 ENST00000451378.2
NADH:ubiquinone oxidoreductase complex assembly factor 3
chr11_-_69819410 0.19 ENST00000334134.4
fibroblast growth factor 3
chr14_-_106235582 0.19 ENST00000390607.2
immunoglobulin heavy variable 3-21
chr1_+_19882374 0.19 ENST00000375120.4
OTU deubiquitinase 3
chr17_+_81528370 0.19 ENST00000417245.7
ENST00000334850.7
fascin actin-bundling protein 2, retinal
chr3_+_49022077 0.19 ENST00000326925.11
NADH:ubiquinone oxidoreductase complex assembly factor 3
chr5_-_134367070 0.19 ENST00000521118.5
cyclin dependent kinase like 3
chr2_-_60550900 0.19 ENST00000643222.1
ENST00000643459.1
ENST00000489516.7
BAF chromatin remodeling complex subunit BCL11A
chr1_+_43300971 0.19 ENST00000372476.8
ENST00000538015.1
tyrosine kinase with immunoglobulin like and EGF like domains 1
chr14_-_20305932 0.19 ENST00000258821.8
ENST00000553828.1
tetratricopeptide repeat domain 5
chr11_-_18791768 0.18 ENST00000358540.7
protein tyrosine phosphatase non-receptor type 5
chr6_+_13013513 0.18 ENST00000675203.1
phosphatase and actin regulator 1
chr12_+_124993633 0.18 ENST00000341446.9
ENST00000671775.2
BRI3 binding protein
chr7_-_99735093 0.18 ENST00000611620.4
ENST00000620220.6
ENST00000336374.4
CYP3A7-CYP3A51P readthrough
cytochrome P450 family 3 subfamily A member 7
chr11_+_18266254 0.18 ENST00000532858.5
ENST00000649195.1
ENST00000356524.9
ENST00000405158.2
serum amyloid A1
chr5_+_140834230 0.18 ENST00000356878.5
ENST00000525929.2
protocadherin alpha 7
chr11_+_63938971 0.18 ENST00000539656.5
ENST00000377793.9
N-alpha-acetyltransferase 40, NatD catalytic subunit
chr19_-_10587219 0.18 ENST00000591240.5
ENST00000589684.5
ENST00000591676.1
ENST00000250244.11
ENST00000590923.5
adaptor related protein complex 1 subunit mu 2
chr8_-_78805515 0.18 ENST00000379113.6
ENST00000541183.2
interleukin 7
chr8_-_78805306 0.18 ENST00000639719.1
ENST00000263851.9
interleukin 7
chr7_+_139829242 0.18 ENST00000455353.6
ENST00000458722.6
ENST00000448866.7
ENST00000411653.6
thromboxane A synthase 1
chr12_-_84912705 0.17 ENST00000679933.1
ENST00000680260.1
ENST00000551010.2
ENST00000679453.1
ENST00000681281.1
solute carrier family 6 member 15
chr3_+_111542178 0.17 ENST00000283285.10
ENST00000352690.9
CD96 molecule
chr11_-_116772972 0.17 ENST00000375445.7
ENST00000260210.5
BUD13 homolog
chr13_-_77919459 0.17 ENST00000643890.1
endothelin receptor type B
chr1_+_161153968 0.17 ENST00000368003.6
ubiquitin-fold modifier conjugating enzyme 1
chr9_+_60914407 0.17 ENST00000437823.5
SPATA31 subfamily A member 5
chrX_+_83508284 0.17 ENST00000644024.2
POU class 3 homeobox 4
chr3_+_44874606 0.17 ENST00000296125.9
transglutaminase 4
chr13_-_37598750 0.17 ENST00000379743.8
ENST00000379742.4
ENST00000379749.8
ENST00000379747.9
ENST00000541179.5
ENST00000541481.5
periostin
chr12_+_63779894 0.16 ENST00000261234.11
ribitol xylosyltransferase 1
chr17_-_28661897 0.16 ENST00000247020.9
stromal cell derived factor 2
chrX_+_8465426 0.16 ENST00000381029.4
variable charge X-linked 3B
chrM_+_9207 0.16 ENST00000362079.2
mitochondrially encoded cytochrome c oxidase III
chrX_-_10677720 0.16 ENST00000453318.6
midline 1
chr2_+_74458400 0.16 ENST00000393972.7
ENST00000233615.7
ENST00000409737.5
ENST00000428943.1
WW domain binding protein 1
chr3_+_133038366 0.16 ENST00000321871.11
ENST00000393130.7
ENST00000514894.5
ENST00000512662.5
transmembrane protein 108
chrY_-_13986473 0.16 ENST00000250825.5
variable charge Y-linked
chr4_-_144140683 0.16 ENST00000324022.14
glycophorin A (MNS blood group)
chr11_+_66480007 0.16 ENST00000531863.5
ENST00000532677.5
dipeptidyl peptidase 3
chr1_+_13171848 0.15 ENST00000415919.3
PRAME family member 9
chr1_-_44355061 0.15 ENST00000649995.1
ENST00000457571.1
ENST00000372257.7
ENST00000452396.5
ERI1 exoribonuclease family member 3
chr12_-_54984667 0.15 ENST00000524668.5
ENST00000533607.1
ENST00000449076.6
thymocyte expressed, positive selection associated 1
chr6_-_29005313 0.15 ENST00000377179.4
zinc finger protein 311
chr17_-_27893339 0.15 ENST00000460380.6
ENST00000379102.8
ENST00000508862.5
ENST00000582441.1
LYR motif containing 9
novel protein
chr8_+_42338477 0.15 ENST00000518925.5
ENST00000265421.9
DNA polymerase beta
chr16_+_21663968 0.15 ENST00000646100.2
otoancorin
chr8_-_118111806 0.15 ENST00000378204.7
exostosin glycosyltransferase 1
chr6_+_17393576 0.15 ENST00000229922.7
ENST00000611958.4
cyclase associated actin cytoskeleton regulatory protein 2
chr3_+_179604785 0.15 ENST00000611971.4
ENST00000493866.5
ENST00000259037.8
ENST00000472629.5
ENST00000482604.5
NADH:ubiquinone oxidoreductase subunit B5
chr19_+_48756067 0.15 ENST00000222157.5
fibroblast growth factor 21
chr1_-_100895132 0.15 ENST00000535414.5
exostosin like glycosyltransferase 2
chr6_+_17393505 0.14 ENST00000616440.4
cyclase associated actin cytoskeleton regulatory protein 2
chr17_-_3292600 0.14 ENST00000615105.1
olfactory receptor family 3 subfamily A member 1
chr7_-_50093204 0.14 ENST00000419417.5
ENST00000046087.7
zona pellucida binding protein
chr12_-_88029385 0.14 ENST00000298699.7
ENST00000550553.5
chromosome 12 open reading frame 50
chr13_+_113209597 0.14 ENST00000488558.2
ENST00000375440.9
cullin 4A
chr16_-_4752565 0.13 ENST00000588099.1
ENST00000588942.1
novel transcript
zinc finger protein 500
chr6_+_32024278 0.13 ENST00000647698.1
complement C4B (Chido blood group)
chr16_+_30378312 0.13 ENST00000528032.5
ENST00000622647.3
zinc finger protein 48
chr10_-_95693893 0.13 ENST00000371209.5
ENST00000680144.1
ENST00000430368.6
ENST00000371217.10
tectonic family member 3
chr11_+_4704782 0.13 ENST00000380390.6
matrix metallopeptidase 26
chr16_-_88686453 0.13 ENST00000332281.6
snail family transcriptional repressor 3
chr19_+_13764502 0.13 ENST00000040663.8
ENST00000319545.12
methylthioribose-1-phosphate isomerase 1
chr1_+_202203721 0.13 ENST00000255432.11
leucine rich repeat containing G protein-coupled receptor 6
chr6_-_168319691 0.13 ENST00000610183.1
ENST00000607983.1
dishevelled binding antagonist of beta catenin 2
chr12_-_21774688 0.13 ENST00000240662.3
potassium inwardly rectifying channel subfamily J member 8
chr3_-_71064964 0.13 ENST00000650387.1
forkhead box P1
chr2_+_64988469 0.13 ENST00000531327.5
solute carrier family 1 member 4
chr6_-_168319762 0.13 ENST00000366795.4
dishevelled binding antagonist of beta catenin 2
chr10_-_101839818 0.13 ENST00000348850.9
potassium voltage-gated channel interacting protein 2
chr1_-_23217482 0.12 ENST00000374619.2
5-hydroxytryptamine receptor 1D
chrX_+_54808334 0.12 ENST00000218439.8
MAGE family member D2
chr3_+_51829417 0.12 ENST00000440739.3
ENST00000444293.5
IQ motif containing F3
chr4_-_112636858 0.12 ENST00000503172.5
ENST00000505019.6
ENST00000309071.9
zinc finger GRF-type containing 1
chr20_+_31879798 0.12 ENST00000620043.4
tubulin tyrosine ligase like 9
chr3_-_150546403 0.12 ENST00000239944.7
ENST00000491660.1
ENST00000487153.1
stress associated endoplasmic reticulum protein 1
chr4_-_38782970 0.12 ENST00000502321.5
ENST00000308973.9
ENST00000613579.4
ENST00000361424.6
ENST00000622002.4
toll like receptor 10
chr5_-_151758639 0.12 ENST00000522710.1
antioxidant 1 copper chaperone
chr16_+_16379055 0.12 ENST00000530217.2
nuclear pore complex interacting protein family member A7

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.6 GO:1904021 negative regulation of G-protein coupled receptor internalization(GO:1904021)
0.5 2.4 GO:1902847 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.3 0.8 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.3 0.8 GO:0014813 skeletal muscle satellite cell commitment(GO:0014813)
0.2 0.6 GO:0030185 nitric oxide transport(GO:0030185)
0.2 0.5 GO:2000439 positive regulation of monocyte extravasation(GO:2000439)
0.2 0.7 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.2 0.5 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.1 0.4 GO:0019542 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate biosynthetic process(GO:0019542)
0.1 0.4 GO:0010193 response to ozone(GO:0010193)
0.1 0.3 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.1 0.3 GO:1990523 bone regeneration(GO:1990523)
0.1 0.3 GO:0042495 detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.1 0.3 GO:0034699 transforming growth factor beta receptor complex assembly(GO:0007181) response to luteinizing hormone(GO:0034699)
0.1 0.2 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.1 0.4 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 0.3 GO:0021569 rhombomere 3 development(GO:0021569)
0.1 0.3 GO:1900108 inner medullary collecting duct development(GO:0072061) negative regulation of nodal signaling pathway(GO:1900108)
0.1 1.2 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.1 0.5 GO:0060423 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.0 0.2 GO:1990167 protein K6-linked deubiquitination(GO:0044313) protein K27-linked deubiquitination(GO:1990167)
0.0 0.2 GO:1904799 negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.0 0.5 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.2 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.3 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.3 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.2 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.2 GO:0006288 base-excision repair, DNA ligation(GO:0006288)
0.0 0.9 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.3 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.5 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.1 GO:1904640 response to methionine(GO:1904640)
0.0 0.4 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.2 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.2 GO:0015680 intracellular copper ion transport(GO:0015680)
0.0 0.3 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.4 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.6 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:0002290 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.0 0.2 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.4 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.5 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.2 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.2 GO:1904396 regulation of neuromuscular junction development(GO:1904396)
0.0 0.2 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.2 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.0 0.5 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.5 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0 0.5 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.3 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 1.2 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.1 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.0 0.2 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.0 0.2 GO:0036309 protein localization to M-band(GO:0036309)
0.0 0.1 GO:2000819 regulation of nucleotide-excision repair(GO:2000819)
0.0 0.1 GO:1900110 negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939)
0.0 0.1 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.1 GO:0044691 tooth eruption(GO:0044691)
0.0 0.2 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.2 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.0 GO:0045554 TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556)
0.0 1.0 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.8 GO:0097484 dendrite extension(GO:0097484)
0.0 0.9 GO:0010107 potassium ion import(GO:0010107)
0.0 0.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.1 GO:0097623 potassium ion export across plasma membrane(GO:0097623)
0.0 0.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.8 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.4 GO:0006833 water transport(GO:0006833)
0.0 0.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.1 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.0 0.1 GO:0032490 detection of molecule of bacterial origin(GO:0032490)
0.0 0.1 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.1 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.2 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.5 GO:0048713 regulation of oligodendrocyte differentiation(GO:0048713)
0.0 0.1 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.7 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.0 0.7 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.1 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.1 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.0 0.1 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.4 GO:0097418 neurofibrillary tangle(GO:0097418)
0.1 0.6 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.3 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.1 0.3 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.6 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.3 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.4 GO:0000322 storage vacuole(GO:0000322)
0.0 0.5 GO:0033391 chromatoid body(GO:0033391)
0.0 0.1 GO:0033011 perinuclear theca(GO:0033011)
0.0 0.3 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 0.3 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.2 GO:0060091 kinocilium(GO:0060091)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0005960 glycine cleavage complex(GO:0005960)
0.0 0.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.3 GO:0032982 myosin filament(GO:0032982)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.6 GO:0031687 A2A adenosine receptor binding(GO:0031687)
0.2 0.8 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.2 0.5 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.2 1.0 GO:0004127 cytidylate kinase activity(GO:0004127)
0.1 0.4 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 2.4 GO:0051787 misfolded protein binding(GO:0051787)
0.1 0.5 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.1 0.3 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.1 0.6 GO:0030492 hemoglobin binding(GO:0030492)
0.1 1.2 GO:1990459 transferrin receptor binding(GO:1990459)
0.1 0.4 GO:0004096 catalase activity(GO:0004096)
0.1 0.2 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.1 0.5 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.2 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1 1.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.1 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.1 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.0 0.6 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.2 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.0 0.3 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.0 0.2 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.2 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.8 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.5 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 1.1 GO:0005549 odorant binding(GO:0005549)
0.0 0.2 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.3 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.3 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.0 0.1 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.1 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.5 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.4 GO:0015250 water channel activity(GO:0015250)
0.0 0.2 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.3 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.3 GO:0004568 chitinase activity(GO:0004568)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.0 0.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0008430 selenium binding(GO:0008430)
0.0 0.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.8 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.3 GO:0043495 protein anchor(GO:0043495)
0.0 0.4 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.3 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.7 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.4 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.1 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.2 PID BMP PATHWAY BMP receptor signaling
0.0 2.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.4 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.8 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.1 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.5 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.1 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones