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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for HOXA2_HOXB1

Z-value: 0.53

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Transcription factors associated with HOXA2_HOXB1

Gene Symbol Gene ID Gene Info
ENSG00000105996.7 HOXA2
ENSG00000120094.9 HOXB1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXA2hg38_v1_chr7_-_27102669_271026910.164.0e-01Click!
HOXB1hg38_v1_chr17_-_48530910_48531026-0.096.5e-01Click!

Activity profile of HOXA2_HOXB1 motif

Sorted Z-values of HOXA2_HOXB1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA2_HOXB1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr16_-_67393486 3.17 ENST00000562206.1
ENST00000393957.7
ENST00000290942.9
tubulin polymerization promoting protein family member 3
chr2_-_153478753 1.47 ENST00000325926.4
reprimo, TP53 dependent G2 arrest mediator homolog
chr15_-_93073111 1.35 ENST00000557420.1
ENST00000542321.6
repulsive guidance molecule BMP co-receptor a
chr13_+_42781547 1.13 ENST00000537894.5
family with sequence similarity 216 member B
chr13_+_42781578 1.12 ENST00000313851.3
family with sequence similarity 216 member B
chr1_-_66924791 0.88 ENST00000371023.7
ENST00000371022.3
ENST00000371026.8
dynein axonemal intermediate chain 4
chr6_+_151239951 0.86 ENST00000402676.7
A-kinase anchoring protein 12
chr2_+_26401909 0.74 ENST00000288710.7
dynein regulatory complex subunit 1
chr10_-_77637558 0.69 ENST00000372421.10
ENST00000639370.1
ENST00000640773.1
ENST00000638895.1
potassium calcium-activated channel subfamily M alpha 1
chr9_+_137241277 0.57 ENST00000340384.5
tubulin beta 4B class IVb
chr10_-_77637902 0.57 ENST00000286627.10
ENST00000639486.1
ENST00000640523.1
potassium calcium-activated channel subfamily M alpha 1
chrX_+_96684801 0.50 ENST00000324765.13
diaphanous related formin 2
chr22_-_30470577 0.48 ENST00000435069.1
ENST00000540910.5
SEC14 like lipid binding 3
chr10_-_77637444 0.45 ENST00000639205.1
ENST00000639498.1
ENST00000372408.7
ENST00000372403.9
ENST00000640626.1
ENST00000404857.6
ENST00000638252.1
ENST00000640029.1
ENST00000640934.1
ENST00000639823.1
ENST00000372437.6
ENST00000639344.1
potassium calcium-activated channel subfamily M alpha 1
chr12_-_14885845 0.42 ENST00000539261.6
ENST00000228938.5
matrix Gla protein
chrX_+_96684638 0.36 ENST00000355827.8
ENST00000373061.7
diaphanous related formin 2
chr6_+_122996227 0.32 ENST00000275162.10
clavesin 2
chr4_-_89836213 0.31 ENST00000618500.4
ENST00000508895.5
synuclein alpha
chr13_+_35476740 0.30 ENST00000537702.5
neurobeachin
chrX_+_96684712 0.29 ENST00000373049.8
diaphanous related formin 2
chr1_-_223363337 0.29 ENST00000608996.5
sushi domain containing 4
chr17_+_7855055 0.28 ENST00000574668.1
ENST00000301599.7
transmembrane protein 88
chr12_+_57216779 0.28 ENST00000349394.6
neurexophilin 4
chr9_+_26947039 0.26 ENST00000519968.5
ENST00000433700.5
intraflagellar transport 74
chr1_-_217076889 0.26 ENST00000493748.5
ENST00000463665.5
estrogen related receptor gamma
chr8_+_103140692 0.26 ENST00000438105.2
ENST00000309982.10
ENST00000297574.6
BAALC binder of MAP3K1 and KLF4
chr10_-_77637789 0.26 ENST00000481070.1
ENST00000640969.1
ENST00000286628.14
ENST00000638991.1
ENST00000639913.1
ENST00000480683.2
potassium calcium-activated channel subfamily M alpha 1
chr4_+_76435216 0.26 ENST00000296043.7
shroom family member 3
chr4_-_89835617 0.25 ENST00000611107.1
ENST00000345009.8
ENST00000505199.5
ENST00000502987.5
synuclein alpha
chr10_+_94089067 0.23 ENST00000371375.1
ENST00000675218.1
phospholipase C epsilon 1
chr3_-_51779187 0.22 ENST00000398780.5
ENST00000668964.1
ENST00000667863.2
ENST00000647442.1
IQ motif containing F6
chr10_+_94089034 0.22 ENST00000676102.1
ENST00000371385.8
phospholipase C epsilon 1
chr12_-_57078739 0.22 ENST00000379391.7
nuclear envelope integral membrane protein 1
chr8_-_142879820 0.22 ENST00000377675.3
ENST00000517471.5
ENST00000292427.10
cytochrome P450 family 11 subfamily B member 1
chrX_-_10677720 0.22 ENST00000453318.6
midline 1
chr2_-_212124901 0.22 ENST00000402597.6
erb-b2 receptor tyrosine kinase 4
chr14_-_21048431 0.22 ENST00000555026.5
NDRG family member 2
chr7_-_144259722 0.21 ENST00000493325.1
olfactory receptor family 2 subfamily A member 7
chr10_-_77637721 0.20 ENST00000638848.1
ENST00000639406.1
ENST00000618048.2
ENST00000639120.1
ENST00000640834.1
ENST00000639601.1
ENST00000638514.1
ENST00000457953.6
ENST00000639090.1
ENST00000639489.1
ENST00000372440.6
ENST00000404771.8
ENST00000638203.1
ENST00000638306.1
ENST00000638351.1
ENST00000638606.1
ENST00000639591.1
ENST00000640182.1
ENST00000640605.1
ENST00000640141.1
potassium calcium-activated channel subfamily M alpha 1
chr11_+_31816266 0.20 ENST00000644607.1
ENST00000646221.1
ENST00000643671.1
ENST00000643931.1
ENST00000642614.1
ENST00000642818.1
ENST00000645848.1
ENST00000506388.2
ENST00000645824.1
ENST00000532942.5
PAX6 upstream antisense RNA
novel protein
chr12_-_57078784 0.20 ENST00000300128.9
nuclear envelope integral membrane protein 1
chr18_+_59220149 0.19 ENST00000256857.7
ENST00000529320.2
ENST00000420468.6
gastrin releasing peptide
chr1_-_91886144 0.19 ENST00000212355.9
transforming growth factor beta receptor 3
chr1_-_182672232 0.19 ENST00000508450.5
regulator of G protein signaling 8
chr11_-_111911759 0.19 ENST00000650687.2
crystallin alpha B
chr1_-_107965009 0.18 ENST00000527011.5
ENST00000370056.9
vav guanine nucleotide exchange factor 3
chrX_+_126819720 0.18 ENST00000371125.4
proline rich 32
chr16_+_15502266 0.17 ENST00000452191.6
bMERB domain containing 1
chr1_-_182672882 0.16 ENST00000367557.8
ENST00000258302.8
regulator of G protein signaling 8
chr7_-_27130733 0.16 ENST00000428284.2
ENST00000360046.10
ENST00000610970.1
homeobox A4
chr17_-_1684807 0.16 ENST00000577001.1
ENST00000572621.5
ENST00000304992.11
pre-mRNA processing factor 8
chr17_-_44199206 0.15 ENST00000589805.1
ataxin 7 like 3
chr7_-_144410227 0.15 ENST00000467773.1
ENST00000483238.5
NOBOX oogenesis homeobox
chr13_-_77919459 0.15 ENST00000643890.1
endothelin receptor type B
chr3_+_156142962 0.15 ENST00000471742.5
potassium voltage-gated channel subfamily A member regulatory beta subunit 1
chr1_-_43367689 0.14 ENST00000621943.4
ELOVL fatty acid elongase 1
chr10_-_97185920 0.14 ENST00000371041.3
ENST00000266058.9
slit guidance ligand 1
chr5_+_167754918 0.14 ENST00000519204.5
teneurin transmembrane protein 2
chr12_+_56021005 0.14 ENST00000547167.6
IKAROS family zinc finger 4
chr10_+_24466487 0.14 ENST00000396446.5
ENST00000396445.5
ENST00000376451.4
KIAA1217
chr6_+_68635273 0.13 ENST00000370598.6
adhesion G protein-coupled receptor B3
chr7_-_78771265 0.13 ENST00000630991.2
ENST00000629359.2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr9_-_124507382 0.13 ENST00000373588.9
ENST00000620110.4
nuclear receptor subfamily 5 group A member 1
chr1_-_43368039 0.13 ENST00000413844.3
ELOVL fatty acid elongase 1
chr5_+_163437569 0.12 ENST00000512163.5
ENST00000393929.5
ENST00000510097.5
ENST00000340828.7
ENST00000511490.4
ENST00000510664.5
cyclin G1
chr1_-_43367956 0.12 ENST00000372458.8
ELOVL fatty acid elongase 1
chr6_+_33420052 0.12 ENST00000646630.1
ENST00000629380.3
synaptic Ras GTPase activating protein 1
chr7_-_78771108 0.12 ENST00000626691.2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr3_-_150546403 0.11 ENST00000239944.7
ENST00000491660.1
ENST00000487153.1
stress associated endoplasmic reticulum protein 1
chr10_-_77637633 0.11 ENST00000638223.1
ENST00000639544.1
ENST00000640807.1
ENST00000434208.6
ENST00000626620.3
ENST00000638575.1
ENST00000638759.1
potassium calcium-activated channel subfamily M alpha 1
chr3_+_148827800 0.11 ENST00000282957.9
ENST00000468341.1
carboxypeptidase B1
chr17_+_60677822 0.11 ENST00000407086.8
ENST00000589222.5
ENST00000626960.2
ENST00000390652.9
BCAS3 microtubule associated cell migration factor
chr6_+_33420201 0.10 ENST00000644458.1
ENST00000449372.7
ENST00000628646.2
ENST00000418600.7
synaptic Ras GTPase activating protein 1
chrX_+_77447387 0.09 ENST00000439435.3
fibroblast growth factor 16
chr16_-_49856105 0.09 ENST00000563137.7
zinc finger protein 423
chr4_-_5019437 0.09 ENST00000506508.1
ENST00000509419.1
ENST00000307746.9
cytokine like 1
chr17_+_45161864 0.09 ENST00000589230.6
ENST00000591576.5
ENST00000591070.6
ENST00000592695.1
HEXIM P-TEFb complex subunit 2
chr2_-_49154433 0.08 ENST00000454032.5
ENST00000304421.8
follicle stimulating hormone receptor
chr10_+_18400562 0.08 ENST00000377315.5
ENST00000650685.1
calcium voltage-gated channel auxiliary subunit beta 2
chr7_-_126533850 0.08 ENST00000444921.3
glutamate metabotropic receptor 8
chr16_+_30069539 0.08 ENST00000565355.1
aldolase, fructose-bisphosphate A
chr15_+_52019206 0.08 ENST00000681888.1
ENST00000261845.7
ENST00000680066.1
ENST00000680777.1
ENST00000680652.1
mitogen-activated protein kinase 6
chr2_-_49154507 0.08 ENST00000406846.7
follicle stimulating hormone receptor
chr6_-_131701401 0.08 ENST00000315453.4
olfactory receptor family 2 subfamily A member 4
chr7_-_27102669 0.07 ENST00000222718.7
homeobox A2
chr14_+_22516273 0.07 ENST00000390510.1
T cell receptor alpha joining 27
chr8_+_142449430 0.07 ENST00000643448.1
ENST00000517894.5
adhesion G protein-coupled receptor B1
chr17_-_48545077 0.07 ENST00000330070.6
homeobox B2
chr7_-_101237827 0.07 ENST00000611078.4
claudin 15
chr12_+_56007484 0.06 ENST00000262032.9
IKAROS family zinc finger 4
chr15_+_47717344 0.06 ENST00000558816.5
ENST00000536845.7
semaphorin 6D
chr2_-_152098810 0.06 ENST00000636442.1
ENST00000638005.1
calcium voltage-gated channel auxiliary subunit beta 4
chr17_-_39197696 0.06 ENST00000394310.7
ENST00000622445.4
ENST00000344140.5
calcium voltage-gated channel auxiliary subunit beta 1
chr7_+_33904911 0.05 ENST00000297161.6
BMP binding endothelial regulator
chr5_-_179617581 0.05 ENST00000523449.5
heterogeneous nuclear ribonucleoprotein H1
chr15_-_64381431 0.05 ENST00000558008.3
ENST00000300035.9
ENST00000559519.5
ENST00000380258.6
PCNA clamp associated factor
chr14_-_81427390 0.05 ENST00000555447.5
stonin 2
chr11_-_2140967 0.05 ENST00000381389.5
insulin like growth factor 2
chr7_-_13989658 0.04 ENST00000430479.6
ENST00000433547.1
ENST00000405192.6
ETS variant transcription factor 1
chr11_-_123058991 0.04 ENST00000526686.1
heat shock protein family A (Hsp70) member 8
chr18_-_55403682 0.04 ENST00000564228.5
ENST00000630828.2
transcription factor 4
chr6_-_32128191 0.04 ENST00000453203.2
ENST00000375203.8
ENST00000375201.8
activating transcription factor 6 beta
chr1_-_160579439 0.04 ENST00000368054.8
ENST00000368048.7
ENST00000311224.8
ENST00000368051.3
ENST00000534968.5
CD84 molecule
chr11_-_123059413 0.03 ENST00000524552.5
heat shock protein family A (Hsp70) member 8
chr7_-_120857124 0.03 ENST00000441017.5
ENST00000424710.5
ENST00000433758.5
tetraspanin 12
chr10_-_63269057 0.03 ENST00000542921.5
jumonji domain containing 1C
chr8_-_78805306 0.03 ENST00000639719.1
ENST00000263851.9
interleukin 7
chr9_+_110668854 0.03 ENST00000189978.10
ENST00000374440.7
muscle associated receptor tyrosine kinase
chr7_-_13989891 0.03 ENST00000405218.6
ETS variant transcription factor 1
chr1_+_243256034 0.03 ENST00000366541.8
SHH signaling and ciliogenesis regulator SDCCAG8
chr10_+_35175586 0.03 ENST00000494479.5
ENST00000463314.5
ENST00000342105.7
ENST00000495301.1
cAMP responsive element modulator
chr2_-_144520315 0.03 ENST00000465070.5
ENST00000465308.5
ENST00000636471.1
ENST00000629520.2
ENST00000675069.1
ENST00000636026.2
ENST00000444559.5
zinc finger E-box binding homeobox 2
chr4_-_108168919 0.03 ENST00000265165.6
lymphoid enhancer binding factor 1
chr17_-_39197652 0.03 ENST00000394303.8
calcium voltage-gated channel auxiliary subunit beta 1
chr9_+_110668779 0.03 ENST00000416899.7
ENST00000374448.9
muscle associated receptor tyrosine kinase
chr17_+_81528370 0.02 ENST00000417245.7
ENST00000334850.7
fascin actin-bundling protein 2, retinal
chr1_+_64470120 0.02 ENST00000651257.2
cache domain containing 1
chr8_-_78805515 0.02 ENST00000379113.6
ENST00000541183.2
interleukin 7
chr11_-_127000762 0.02 ENST00000525144.7
kirre like nephrin family adhesion molecule 3
chr12_-_88029385 0.02 ENST00000298699.7
ENST00000550553.5
chromosome 12 open reading frame 50
chr11_+_26188836 0.02 ENST00000672621.1
anoctamin 3
chr19_+_35358821 0.02 ENST00000594310.1
free fatty acid receptor 3
chr4_-_108168950 0.02 ENST00000379951.6
lymphoid enhancer binding factor 1
chrX_+_100644183 0.02 ENST00000640889.1
ENST00000373004.5
sushi repeat containing protein X-linked 2
chr12_+_57089094 0.01 ENST00000342556.6
ENST00000300131.8
NGFI-A binding protein 2
chrX_-_111412162 0.01 ENST00000637570.1
ENST00000356220.8
ENST00000636035.2
ENST00000637453.1
ENST00000635795.1
doublecortin
chr12_-_48999363 0.01 ENST00000421952.3
dendrin
chr7_+_20330893 0.01 ENST00000222573.5
integrin subunit beta 8
chr20_+_36154630 0.01 ENST00000338074.7
ENST00000636016.2
ENST00000373945.5
erythrocyte membrane protein band 4.1 like 1
chrX_+_48597482 0.01 ENST00000218056.9
ENST00000376729.10
WD repeat domain 13
chr3_+_189789672 0.01 ENST00000434928.5
tumor protein p63
chr1_-_109041986 0.01 ENST00000400794.7
ENST00000528747.1
ENST00000361054.7
WD repeat domain 47
chr21_+_18244828 0.00 ENST00000299295.7
chondrolectin
chr20_+_36214373 0.00 ENST00000432603.1
erythrocyte membrane protein band 4.1 like 1
chrX_-_66033664 0.00 ENST00000427538.5
V-set and immunoglobulin domain containing 4
chr17_+_39668447 0.00 ENST00000269582.3
ENST00000581428.1
phenylethanolamine N-methyltransferase
chr8_+_94641074 0.00 ENST00000423620.6
epithelial splicing regulatory protein 1
chr21_-_42010327 0.00 ENST00000398505.7
ENST00000449949.5
ENST00000310826.10
ENST00000398499.5
ENST00000398497.2
ENST00000398511.3
zinc finger and BTB domain containing 21
chrX_+_70062457 0.00 ENST00000338352.3
OTU deubiquitinase 6A

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.3 GO:0034465 response to carbon monoxide(GO:0034465)
0.1 0.6 GO:1903284 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1 0.2 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.1 0.5 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.7 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 1.3 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.1 0.2 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.0 0.2 GO:0034699 transforming growth factor beta receptor complex assembly(GO:0007181) response to luteinizing hormone(GO:0034699)
0.0 0.2 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 0.4 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0021569 rhombomere 3 development(GO:0021569)
0.0 0.1 GO:0099558 maintenance of synapse structure(GO:0099558)
0.0 0.1 GO:0007538 primary sex determination(GO:0007538)
0.0 3.9 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.2 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.2 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.3 GO:0045176 apical protein localization(GO:0045176)
0.0 0.4 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.4 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.1 GO:1902904 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 0.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:2000546 positive regulation of fat cell proliferation(GO:0070346) positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.0 0.2 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0035645 enteric smooth muscle cell differentiation(GO:0035645)
0.0 0.2 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 1.3 GO:0048477 oogenesis(GO:0048477)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.2 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 2.3 GO:0005901 caveola(GO:0005901)
0.0 0.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:0097512 cardiac myofibril(GO:0097512)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.3 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.6 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 1.3 GO:1990459 transferrin receptor binding(GO:1990459)
0.1 0.2 GO:0004507 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.1 0.2 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.1 0.2 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.7 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.4 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.3 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.6 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.2 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.2 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.1 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 PID BMP PATHWAY BMP receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.6 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs