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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for HOXB3

Z-value: 0.41

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Transcription factors associated with HOXB3

Gene Symbol Gene ID Gene Info
HOXB3
ENSG00000120093.12 HOXB3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXB3hg38_v1_chr17_-_48590231_485902580.057.9e-01Click!

Activity profile of HOXB3 motif

Sorted Z-values of HOXB3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB3

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr1_+_152514474 1.37 ENST00000368790.4
CRCT1
cysteine rich C-terminal 1
chr22_+_30396991 0.78 ENST00000617837.4
ENST00000615189.5
ENST00000405717.7
ENST00000402592.7
SEC14L2
SEC14 like lipid binding 2
chr4_+_85604146 0.74 ENST00000512201.5
ARHGAP24
Rho GTPase activating protein 24
chr5_-_22853320 0.66 ENST00000504376.6
ENST00000382254.6
CDH12
cadherin 12
chr3_+_122055355 0.61 ENST00000330540.7
ENST00000469710.5
ENST00000493101.5
CD86
CD86 molecule
chr2_+_113058637 0.57 ENST00000346807.7
IL36RN
interleukin 36 receptor antagonist
chr22_+_44026283 0.53 ENST00000619710.4
PARVB
parvin beta
chr2_+_113059194 0.51 ENST00000393200.7
IL36RN
interleukin 36 receptor antagonist
chr4_-_149815826 0.51 ENST00000636793.2
ENST00000636414.1
IQCM
IQ motif containing M
chr11_-_107858777 0.49 ENST00000525815.6
SLC35F2
solute carrier family 35 member F2
chrX_+_139530730 0.49 ENST00000218099.7
F9
coagulation factor IX
chr12_+_15546344 0.48 ENST00000674388.1
ENST00000542557.5
ENST00000445537.6
ENST00000544244.5
ENST00000442921.7
PTPRO
protein tyrosine phosphatase receptor type O
chr3_-_52535006 0.47 ENST00000307076.8
NT5DC2
5'-nucleotidase domain containing 2
chr17_+_42458844 0.47 ENST00000393829.6
ENST00000537728.5
ENST00000343619.9
ENST00000264649.10
ENST00000585525.5
ENST00000544137.5
ENST00000589727.5
ENST00000587824.5
ATP6V0A1
ATPase H+ transporting V0 subunit a1
chr11_+_33039996 0.46 ENST00000432887.5
ENST00000528898.1
ENST00000531632.6
TCP11L1
t-complex 11 like 1
chr8_+_27311471 0.44 ENST00000397501.5
PTK2B
protein tyrosine kinase 2 beta
chr9_+_72577369 0.43 ENST00000651183.1
TMC1
transmembrane channel like 1
chr12_-_10826358 0.42 ENST00000240619.2
TAS2R10
taste 2 receptor member 10
chr4_+_143433491 0.41 ENST00000512843.1
GAB1
GRB2 associated binding protein 1
chr11_-_124320197 0.41 ENST00000624618.2
OR8D2
olfactory receptor family 8 subfamily D member 2
chr3_+_136819069 0.39 ENST00000393079.3
ENST00000446465.3
SLC35G2
solute carrier family 35 member G2
chr5_+_151259793 0.39 ENST00000523004.1
GM2A
GM2 ganglioside activator
chr8_-_30812867 0.38 ENST00000518243.5
PPP2CB
protein phosphatase 2 catalytic subunit beta
chr2_+_44275457 0.38 ENST00000611973.4
ENST00000409387.5
SLC3A1
solute carrier family 3 member 1
chr12_-_122703346 0.37 ENST00000328880.6
HCAR2
hydroxycarboxylic acid receptor 2
chr22_-_29838227 0.35 ENST00000307790.8
ENST00000397771.6
ENST00000542393.5
ASCC2
activating signal cointegrator 1 complex subunit 2
chr3_-_185821092 0.34 ENST00000421047.3
IGF2BP2
insulin like growth factor 2 mRNA binding protein 2
chr12_+_20695553 0.33 ENST00000545102.1
SLCO1C1
solute carrier organic anion transporter family member 1C1
chr21_+_42403874 0.32 ENST00000319294.11
ENST00000398367.1
UBASH3A
ubiquitin associated and SH3 domain containing A
chr9_+_133061981 0.32 ENST00000372080.8
CEL
carboxyl ester lipase
chrX_+_111876177 0.32 ENST00000635763.2
TRPC5OS
TRPC5 opposite strand
chr8_-_48921419 0.32 ENST00000020945.4
SNAI2
snail family transcriptional repressor 2
chr12_-_122716790 0.32 ENST00000528880.3
HCAR3
hydroxycarboxylic acid receptor 3
chr9_+_122371036 0.31 ENST00000619306.5
ENST00000426608.6
ENST00000223423.8
PTGS1
prostaglandin-endoperoxide synthase 1
chr8_-_13276491 0.31 ENST00000512044.6
DLC1
DLC1 Rho GTPase activating protein
chr7_-_101217569 0.31 ENST00000223127.8
PLOD3
procollagen-lysine,2-oxoglutarate 5-dioxygenase 3
chr9_+_72577788 0.31 ENST00000645208.2
TMC1
transmembrane channel like 1
chr4_+_122378966 0.30 ENST00000446706.5
ENST00000296513.7
ADAD1
adenosine deaminase domain containing 1
chr11_-_118264445 0.30 ENST00000438295.2
MPZL2
myelin protein zero like 2
chr6_-_110179995 0.30 ENST00000392586.5
ENST00000419252.1
ENST00000359451.6
ENST00000392588.5
WASF1
WASP family member 1
chr12_-_52652207 0.29 ENST00000309680.4
KRT2
keratin 2
chr7_-_100167284 0.28 ENST00000413800.5
GAL3ST4
galactose-3-O-sulfotransferase 4
chr8_+_7926337 0.27 ENST00000400120.3
ZNF705B
zinc finger protein 705B
chr14_-_106038355 0.27 ENST00000390597.3
IGHV2-5
immunoglobulin heavy variable 2-5
chr15_+_71810539 0.27 ENST00000617575.5
ENST00000621098.1
NR2E3
nuclear receptor subfamily 2 group E member 3
chr2_+_90038848 0.27 ENST00000390270.2
IGKV3D-20
immunoglobulin kappa variable 3D-20
chr9_+_131289685 0.27 ENST00000372264.4
PLPP7
phospholipid phosphatase 7 (inactive)
chr6_-_116545658 0.27 ENST00000368602.4
TRAPPC3L
trafficking protein particle complex 3 like
chr2_+_27275429 0.26 ENST00000420191.5
ENST00000296097.8
DNAJC5G
DnaJ heat shock protein family (Hsp40) member C5 gamma
chr2_+_48314637 0.26 ENST00000413569.5
ENST00000340553.8
FOXN2
forkhead box N2
chr6_+_160121859 0.26 ENST00000324965.8
ENST00000457470.6
SLC22A1
solute carrier family 22 member 1
chr12_+_22625182 0.26 ENST00000538218.2
ETNK1
ethanolamine kinase 1
chr11_+_65787056 0.25 ENST00000335987.8
OVOL1
ovo like transcriptional repressor 1
chr6_+_54018910 0.25 ENST00000514921.5
ENST00000274897.9
ENST00000370877.6
MLIP
muscular LMNA interacting protein
chr6_+_160121809 0.25 ENST00000366963.9
SLC22A1
solute carrier family 22 member 1
chr8_+_22275309 0.25 ENST00000356766.11
ENST00000521356.5
PIWIL2
piwi like RNA-mediated gene silencing 2
chr8_+_12104389 0.25 ENST00000400085.7
ZNF705D
zinc finger protein 705D
chr14_-_24242320 0.24 ENST00000557921.2
TINF2
TERF1 interacting nuclear factor 2
chr2_+_29113989 0.23 ENST00000404424.5
CLIP4
CAP-Gly domain containing linker protein family member 4
chr1_-_66801276 0.23 ENST00000304526.3
INSL5
insulin like 5
chr20_-_56525925 0.23 ENST00000243913.8
GCNT7
glucosaminyl (N-acetyl) transferase family member 7
chr12_-_7936177 0.23 ENST00000544291.1
ENST00000075120.12
SLC2A3
solute carrier family 2 member 3
chr4_+_25160631 0.23 ENST00000510415.1
ENST00000507794.2
ENST00000512921.4
SEPSECS-AS1
PI4K2B
SEPSECS antisense RNA 1 (head to head)
phosphatidylinositol 4-kinase type 2 beta
chr1_+_15764419 0.22 ENST00000441801.6
FBLIM1
filamin binding LIM protein 1
chr6_+_26204552 0.22 ENST00000615164.2
H4C5
H4 clustered histone 5
chr7_-_111392915 0.22 ENST00000450877.5
IMMP2L
inner mitochondrial membrane peptidase subunit 2
chr19_+_7830188 0.22 ENST00000270530.8
EVI5L
ecotropic viral integration site 5 like
chr19_+_49766962 0.22 ENST00000354293.10
ENST00000359032.9
AP2A1
adaptor related protein complex 2 subunit alpha 1
chr6_-_127459364 0.21 ENST00000487331.2
ENST00000483725.8
KIAA0408
KIAA0408
chr14_+_56117702 0.21 ENST00000559044.5
PELI2
pellino E3 ubiquitin protein ligase family member 2
chr21_-_26051023 0.21 ENST00000415997.1
APP
amyloid beta precursor protein
chr14_+_32329341 0.21 ENST00000557354.5
ENST00000557102.1
ENST00000557272.1
AKAP6
A-kinase anchoring protein 6
chr7_+_120988683 0.21 ENST00000340646.9
ENST00000310396.10
CPED1
cadherin like and PC-esterase domain containing 1
chrX_+_43656289 0.21 ENST00000338702.4
MAOA
monoamine oxidase A
chr19_-_5286163 0.21 ENST00000592099.5
ENST00000588012.5
ENST00000262963.10
ENST00000587303.5
ENST00000590509.5
PTPRS
protein tyrosine phosphatase receptor type S
chr4_-_142846275 0.20 ENST00000513000.5
ENST00000509777.5
ENST00000503927.5
INPP4B
inositol polyphosphate-4-phosphatase type II B
chr8_+_144148027 0.20 ENST00000423230.6
MROH1
maestro heat like repeat family member 1
chr10_-_133565542 0.20 ENST00000303903.10
ENST00000343131.7
SYCE1
synaptonemal complex central element protein 1
chr6_+_130018565 0.20 ENST00000361794.7
ENST00000526087.5
ENST00000533560.5
L3MBTL3
L3MBTL histone methyl-lysine binding protein 3
chr9_+_122371014 0.20 ENST00000362012.7
PTGS1
prostaglandin-endoperoxide synthase 1
chr19_-_3557563 0.19 ENST00000389395.7
ENST00000355415.7
MFSD12
major facilitator superfamily domain containing 12
chr1_+_207053229 0.19 ENST00000367080.8
ENST00000367079.3
PFKFB2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr19_-_17255448 0.19 ENST00000594059.1
ENSG00000269095.1
novel protein
chr15_-_55270280 0.19 ENST00000564609.5
RAB27A
RAB27A, member RAS oncogene family
chr12_-_21910853 0.19 ENST00000544039.5
ABCC9
ATP binding cassette subfamily C member 9
chr18_-_46964408 0.18 ENST00000676383.1
ENSG00000288616.1
elongin A3 family member D
chr2_+_28395511 0.18 ENST00000436647.1
FOSL2
FOS like 2, AP-1 transcription factor subunit
chr18_+_58221535 0.18 ENST00000431212.6
ENST00000586268.5
ENST00000587190.5
NEDD4L
NEDD4 like E3 ubiquitin protein ligase
chrX_-_108736556 0.18 ENST00000372129.4
IRS4
insulin receptor substrate 4
chr15_+_78438279 0.18 ENST00000560440.5
IREB2
iron responsive element binding protein 2
chr2_+_88885397 0.18 ENST00000390243.2
IGKV4-1
immunoglobulin kappa variable 4-1
chr12_+_56128217 0.18 ENST00000267113.4
ENST00000394048.10
ESYT1
extended synaptotagmin 1
chr8_-_7385558 0.17 ENST00000400156.4
ZNF705G
zinc finger protein 705G
chr12_+_8157034 0.17 ENST00000396570.7
ZNF705A
zinc finger protein 705A
chr5_-_126595237 0.17 ENST00000637206.1
ENST00000553117.5
ALDH7A1
aldehyde dehydrogenase 7 family member A1
chr15_-_55270874 0.17 ENST00000567380.5
ENST00000565972.5
ENST00000569493.5
RAB27A
RAB27A, member RAS oncogene family
chr9_+_121567057 0.17 ENST00000394340.7
ENST00000436835.5
ENST00000259371.6
DAB2IP
DAB2 interacting protein
chr14_+_94174284 0.17 ENST00000304338.8
PPP4R4
protein phosphatase 4 regulatory subunit 4
chr19_-_14848922 0.16 ENST00000641129.1
OR7A10
olfactory receptor family 7 subfamily A member 10
chr18_-_24311495 0.16 ENST00000357041.8
OSBPL1A
oxysterol binding protein like 1A
chr6_-_110815408 0.16 ENST00000368911.8
CDK19
cyclin dependent kinase 19
chr12_-_11395556 0.16 ENST00000565533.1
ENST00000389362.6
ENST00000546254.3
PRB2
PRB1
proline rich protein BstNI subfamily 2
proline rich protein BstNI subfamily 1
chr16_+_6019016 0.16 ENST00000550418.6
RBFOX1
RNA binding fox-1 homolog 1
chr2_-_101308681 0.16 ENST00000295317.4
RNF149
ring finger protein 149
chr6_+_47698538 0.16 ENST00000327753.7
ADGRF4
adhesion G protein-coupled receptor F4
chr12_+_119668109 0.16 ENST00000229328.10
ENST00000630317.1
PRKAB1
protein kinase AMP-activated non-catalytic subunit beta 1
chr14_+_94174334 0.16 ENST00000328839.3
PPP4R4
protein phosphatase 4 regulatory subunit 4
chr22_+_22811737 0.15 ENST00000390315.3
IGLV3-10
immunoglobulin lambda variable 3-10
chr17_+_50547089 0.15 ENST00000619622.4
ENST00000356488.8
ENST00000006658.11
SPATA20
spermatogenesis associated 20
chr16_+_11965193 0.15 ENST00000053243.6
ENST00000396495.3
TNFRSF17
TNF receptor superfamily member 17
chr2_+_233636445 0.15 ENST00000344644.9
UGT1A10
UDP glucuronosyltransferase family 1 member A10
chr5_+_149357999 0.15 ENST00000274569.9
PCYOX1L
prenylcysteine oxidase 1 like
chr1_-_207052980 0.15 ENST00000367084.1
YOD1
YOD1 deubiquitinase
chr6_+_47698574 0.14 ENST00000283303.3
ADGRF4
adhesion G protein-coupled receptor F4
chr16_+_11965234 0.14 ENST00000562385.1
TNFRSF17
TNF receptor superfamily member 17
chr17_+_48892761 0.14 ENST00000355938.9
ENST00000393366.7
ENST00000503641.5
ENST00000514808.5
ENST00000506855.1
ATP5MC1
ATP synthase membrane subunit c locus 1
chr22_-_28711931 0.14 ENST00000434810.5
ENST00000456369.5
CHEK2
checkpoint kinase 2
chr2_+_64988469 0.14 ENST00000531327.5
SLC1A4
solute carrier family 1 member 4
chr2_-_199851114 0.14 ENST00000420128.5
ENST00000416668.5
ENST00000622774.2
FTCDNL1
formiminotransferase cyclodeaminase N-terminal like
chr17_-_59151794 0.14 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr16_+_6019071 0.14 ENST00000547605.5
ENST00000553186.5
RBFOX1
RNA binding fox-1 homolog 1
chr3_+_114294020 0.14 ENST00000383671.8
TIGIT
T cell immunoreceptor with Ig and ITIM domains
chr11_+_95789965 0.14 ENST00000537677.5
CEP57
centrosomal protein 57
chr12_-_118359639 0.13 ENST00000541786.5
ENST00000419821.6
ENST00000541878.5
TAOK3
TAO kinase 3
chr6_-_110815152 0.13 ENST00000413605.6
CDK19
cyclin dependent kinase 19
chr19_+_49487510 0.13 ENST00000679106.1
ENST00000621674.4
ENST00000391857.9
ENST00000678510.1
ENST00000467825.2
RPL13A
ribosomal protein L13a
chr2_+_233729042 0.13 ENST00000482026.6
UGT1A3
UDP glucuronosyltransferase family 1 member A3
chr18_+_63887698 0.13 ENST00000457692.5
ENST00000299502.9
ENST00000413956.5
SERPINB2
serpin family B member 2
chr13_+_45464901 0.13 ENST00000349995.10
COG3
component of oligomeric golgi complex 3
chr2_-_165203870 0.13 ENST00000639244.1
ENST00000409101.7
ENST00000668657.1
SCN3A
sodium voltage-gated channel alpha subunit 3
chr15_-_101294905 0.13 ENST00000560496.5
SNRPA1
small nuclear ribonucleoprotein polypeptide A'
chr11_+_24496988 0.13 ENST00000336930.11
LUZP2
leucine zipper protein 2
chrX_-_21658324 0.13 ENST00000379499.3
KLHL34
kelch like family member 34
chr14_-_94476240 0.12 ENST00000424550.6
ENST00000337425.10
ENST00000674164.1
ENST00000546329.2
SERPINA9
serpin family A member 9
chr19_+_48445961 0.12 ENST00000253237.10
GRWD1
glutamate rich WD repeat containing 1
chrX_+_86714623 0.12 ENST00000484479.1
DACH2
dachshund family transcription factor 2
chr12_-_91058016 0.12 ENST00000266719.4
KERA
keratocan
chr2_+_142877653 0.12 ENST00000375773.6
ENST00000409512.5
ENST00000264170.9
ENST00000410015.6
KYNU
kynureninase
chr1_-_51331315 0.12 ENST00000262676.9
TTC39A
tetratricopeptide repeat domain 39A
chr17_-_46361718 0.12 ENST00000575960.5
ENST00000575698.5
ENST00000571246.5
ENST00000434041.6
ENST00000656849.1
ENST00000570618.5
ENST00000450673.4
ENST00000622877.4
ARL17B
ADP ribosylation factor like GTPase 17B
chr6_-_169250825 0.12 ENST00000676869.1
ENST00000676760.1
THBS2
thrombospondin 2
chr4_-_68245683 0.12 ENST00000332644.6
TMPRSS11B
transmembrane serine protease 11B
chr8_+_7836433 0.11 ENST00000314265.3
DEFB104A
defensin beta 104A
chr1_-_197146620 0.11 ENST00000367409.9
ENST00000680265.1
ASPM
assembly factor for spindle microtubules
chr22_-_32255344 0.11 ENST00000266086.6
SLC5A4
solute carrier family 5 member 4
chr19_+_9185594 0.11 ENST00000344248.4
OR7D2
olfactory receptor family 7 subfamily D member 2
chr22_-_28712136 0.11 ENST00000464581.6
CHEK2
checkpoint kinase 2
chr21_+_46286623 0.11 ENST00000397691.1
YBEY
ybeY metalloendoribonuclease
chr1_-_89175997 0.11 ENST00000294671.3
ENST00000650452.1
GBP7
guanylate binding protein 7
chr4_-_110641920 0.11 ENST00000354925.6
ENST00000511990.1
ENST00000613094.4
ENST00000614423.4
ENST00000616641.4
ENST00000511837.5
PITX2
paired like homeodomain 2
chr2_-_88861258 0.11 ENST00000390240.2
IGKJ3
immunoglobulin kappa joining 3
chr3_-_165078480 0.11 ENST00000264382.8
SI
sucrase-isomaltase
chr2_+_86942118 0.10 ENST00000641458.2
RGPD1
RANBP2 like and GRIP domain containing 1
chr11_+_95790459 0.10 ENST00000325486.9
ENST00000325542.10
ENST00000544522.5
ENST00000541365.5
CEP57
centrosomal protein 57
chr1_-_153150884 0.10 ENST00000368748.5
SPRR2G
small proline rich protein 2G
chr12_-_10453330 0.10 ENST00000347831.9
ENST00000359151.8
KLRC1
killer cell lectin like receptor C1
chr6_+_127577168 0.10 ENST00000329722.8
C6orf58
chromosome 6 open reading frame 58
chr1_+_186296267 0.10 ENST00000533951.5
ENST00000367482.8
ENST00000635041.1
ENST00000367483.8
ENST00000367485.4
ENST00000445192.7
PRG4
proteoglycan 4
chr7_-_33062750 0.10 ENST00000610140.7
NT5C3A
5'-nucleotidase, cytosolic IIIA
chr3_+_43690880 0.10 ENST00000458276.7
ABHD5
abhydrolase domain containing 5, lysophosphatidic acid acyltransferase
chr14_-_24242600 0.10 ENST00000646753.1
ENST00000558566.1
ENST00000267415.12
ENST00000559019.1
ENST00000399423.8
ENST00000626689.2
TINF2
TERF1 interacting nuclear factor 2
chrX_+_13689116 0.10 ENST00000464506.2
ENST00000243325.6
RAB9A
RAB9A, member RAS oncogene family
chr1_+_34792990 0.10 ENST00000450137.1
ENST00000342280.5
GJA4
gap junction protein alpha 4
chr7_+_101218146 0.10 ENST00000305105.3
ZNHIT1
zinc finger HIT-type containing 1
chrX_+_91434829 0.10 ENST00000312600.4
PABPC5
poly(A) binding protein cytoplasmic 5
chr8_-_140800535 0.10 ENST00000521986.5
ENST00000523539.5
PTK2
protein tyrosine kinase 2
chr6_+_63571702 0.09 ENST00000672924.1
PTP4A1
protein tyrosine phosphatase 4A1
chr17_-_46579651 0.09 ENST00000573185.5
ENST00000570550.5
ENST00000445552.6
ENST00000329240.10
ENST00000622488.6
ENST00000336125.6
ARL17A
ADP ribosylation factor like GTPase 17A
chr12_+_107685759 0.09 ENST00000412830.8
ENST00000547995.5
PWP1
PWP1 homolog, endonuclein
chrX_+_37349287 0.09 ENST00000466533.5
ENST00000542554.5
ENST00000543642.5
ENST00000484460.5
ENST00000378628.9
ENST00000449135.6
ENST00000463135.1
ENST00000465127.1
PRRG1
ENSG00000250349.3
proline rich and Gla domain 1
novel proline rich Gla (G-carboxyglutamic acid) 1 (PRRG1) and tetraspanin 7 (TSPAN7) protein
chr9_+_12775012 0.09 ENST00000319264.4
LURAP1L
leucine rich adaptor protein 1 like
chr1_+_197268222 0.09 ENST00000367400.8
ENST00000638467.1
ENST00000367399.6
CRB1
crumbs cell polarity complex component 1
chr17_+_50548041 0.09 ENST00000634597.1
SPATA20
spermatogenesis associated 20
chr11_-_13496018 0.09 ENST00000529816.1
PTH
parathyroid hormone
chr1_-_201171545 0.09 ENST00000367333.6
TMEM9
transmembrane protein 9
chr2_+_11542662 0.09 ENST00000389825.7
ENST00000381483.6
GREB1
growth regulating estrogen receptor binding 1
chr11_+_24497155 0.09 ENST00000529015.5
ENST00000533227.5
LUZP2
leucine zipper protein 2
chr5_+_132873660 0.09 ENST00000296877.3
LEAP2
liver enriched antimicrobial peptide 2
chr2_+_233671879 0.09 ENST00000354728.5
UGT1A9
UDP glucuronosyltransferase family 1 member A9
chr1_+_197268204 0.09 ENST00000535699.5
ENST00000538660.5
CRB1
crumbs cell polarity complex component 1
chr1_+_161721563 0.09 ENST00000367948.6
FCRLB
Fc receptor like B
chr19_+_54137740 0.09 ENST00000644245.1
ENST00000646002.1
ENST00000221232.11
ENST00000440571.6
ENST00000617930.2
CNOT3
CCR4-NOT transcription complex subunit 3
chr3_+_122183664 0.09 ENST00000639785.2
CASR
calcium sensing receptor
chr19_+_49527988 0.09 ENST00000270645.8
RCN3
reticulocalbin 3
chr4_+_150078426 0.09 ENST00000296550.12
DCLK2
doublecortin like kinase 2
chrX_-_103502853 0.08 ENST00000372633.1
RAB40A
RAB40A, member RAS oncogene family
chr5_-_34043205 0.08 ENST00000382065.8
ENST00000231338.7
C1QTNF3
C1q and TNF related 3
chr8_-_42768602 0.08 ENST00000534622.5
CHRNA6
cholinergic receptor nicotinic alpha 6 subunit
chr12_-_50249883 0.08 ENST00000550592.1
LIMA1
LIM domain and actin binding 1
chr3_-_151329539 0.08 ENST00000325602.6
P2RY13
purinergic receptor P2Y13
chr14_+_21852457 0.08 ENST00000390435.1
TRAV8-3
T cell receptor alpha variable 8-3
chr14_-_54441325 0.08 ENST00000556113.1
ENST00000553660.5
ENST00000216416.9
ENST00000395573.8
ENST00000557690.5
CNIH1
cornichon family AMPA receptor auxiliary protein 1
chr2_+_186694007 0.08 ENST00000304698.10
FAM171B
family with sequence similarity 171 member B
chr10_-_114144599 0.08 ENST00000428953.1
CCDC186
coiled-coil domain containing 186
chr2_+_137964279 0.08 ENST00000329366.8
HNMT
histamine N-methyltransferase
chr19_-_3985451 0.08 ENST00000309311.7
EEF2
eukaryotic translation elongation factor 2
chr2_+_165239388 0.08 ENST00000424833.5
ENST00000375437.7
ENST00000631182.3
SCN2A
sodium voltage-gated channel alpha subunit 2
chr6_+_24667026 0.08 ENST00000537591.5
ENST00000230048.5
ACOT13
acyl-CoA thioesterase 13
chr3_+_98168700 0.08 ENST00000383696.4
OR5H15
olfactory receptor family 5 subfamily H member 15
chr6_-_118935114 0.08 ENST00000316068.7
MCM9
minichromosome maintenance 9 homologous recombination repair factor

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0043016 negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017)
0.1 0.4 GO:2000538 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.1 1.1 GO:0019732 antifungal humoral response(GO:0019732)
0.1 0.5 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.3 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.1 0.3 GO:1901993 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1 0.3 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.2 GO:0030718 germ-line stem cell population maintenance(GO:0030718) positive regulation of meiosis I(GO:0060903)
0.1 0.3 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.4 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.1 0.7 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.2 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.5 GO:0048241 epinephrine transport(GO:0048241)
0.1 0.3 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.1 0.5 GO:0015811 L-cystine transport(GO:0015811)
0.1 0.3 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.1 0.2 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.1 0.5 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 0.3 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.1 0.5 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.1 0.3 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.2 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.1 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.2 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.4 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.2 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.3 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.1 GO:0021763 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.0 0.1 GO:1990168 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.0 0.2 GO:0051563 microglia differentiation(GO:0014004) microglia development(GO:0014005) collateral sprouting in absence of injury(GO:0048669) smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563) cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.2 GO:0051552 flavone metabolic process(GO:0051552)
0.0 0.5 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.3 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.2 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.2 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.3 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.5 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.0 0.1 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.0 GO:0061760 antifungal innate immune response(GO:0061760)
0.0 0.3 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.2 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.1 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.0 0.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.2 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 0.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.2 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.1 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
0.0 0.0 GO:0001757 somite specification(GO:0001757)
0.0 0.2 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.1 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.4 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.0 0.0 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.1 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.3 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.3 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.0 GO:0032499 detection of peptidoglycan(GO:0032499) activation of MAPK activity involved in innate immune response(GO:0035419) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585) cellular response to muramyl dipeptide(GO:0071225) positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 0.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0042340 keratan sulfate catabolic process(GO:0042340)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.1 0.4 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.1 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.5 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.2 GO:1990032 parallel fiber(GO:1990032)
0.0 0.7 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.2 GO:0000801 central element(GO:0000801)
0.0 0.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.3 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:0097452 GAIT complex(GO:0097452)
0.0 0.2 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.1 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0008431 vitamin E binding(GO:0008431)
0.2 1.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.1 0.4 GO:0030290 sphingolipid activator protein activity(GO:0030290) beta-N-acetylgalactosaminidase activity(GO:0032428)
0.1 0.5 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.1 0.5 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.3 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.1 0.2 GO:0034584 piRNA binding(GO:0034584)
0.1 0.3 GO:0050211 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211)
0.1 0.2 GO:0030350 iron-responsive element binding(GO:0030350)
0.1 0.5 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.1 0.2 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 0.7 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.2 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.3 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.3 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.4 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.2 GO:0034597 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.6 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.2 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 0.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.0 0.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.2 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.1 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.0 0.1 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.0 0.1 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.4 GO:0005549 odorant binding(GO:0005549)
0.0 0.5 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.4 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.3 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.3 GO:0031489 myosin V binding(GO:0031489)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.4 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.6 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.5 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.4 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.6 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.5 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.8 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.2 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.4 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.2 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism